NO996178D0 - 4-aminopyrrol(3,2-d)pyrimidiner som neuropeptid y- reseptorantagonister - Google Patents

4-aminopyrrol(3,2-d)pyrimidiner som neuropeptid y- reseptorantagonister

Info

Publication number
NO996178D0
NO996178D0 NO996178A NO996178A NO996178D0 NO 996178 D0 NO996178 D0 NO 996178D0 NO 996178 A NO996178 A NO 996178A NO 996178 A NO996178 A NO 996178A NO 996178 D0 NO996178 D0 NO 996178D0
Authority
NO
Norway
Prior art keywords
aminopyrrole
neuropeptide
pyrimidines
receptor antagonists
antagonists
Prior art date
Application number
NO996178A
Other languages
English (en)
Other versions
NO996178L (no
Inventor
Robert Lee Dow
Marlys Hammond
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of NO996178D0 publication Critical patent/NO996178D0/no
Publication of NO996178L publication Critical patent/NO996178L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Child & Adolescent Psychology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO996178A 1997-08-05 1999-12-14 4-aminopyrrol(3,2-d)pyrimidiner som neuropeptid y- reseptorantagonister NO996178L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5473497P 1997-08-05 1997-08-05
PCT/IB1998/001053 WO1999007703A1 (en) 1997-08-05 1998-07-10 4-AMINOPYRROLE(3,2-d) PYRIMIDINES AS NEUROPEPTIDE Y RECEPTOR ANTAGONISTS

Publications (2)

Publication Number Publication Date
NO996178D0 true NO996178D0 (no) 1999-12-14
NO996178L NO996178L (no) 2000-02-14

Family

ID=21993163

Family Applications (1)

Application Number Title Priority Date Filing Date
NO996178A NO996178L (no) 1997-08-05 1999-12-14 4-aminopyrrol(3,2-d)pyrimidiner som neuropeptid y- reseptorantagonister

Country Status (32)

Country Link
US (1) US6187778B1 (no)
EP (1) EP1003744B1 (no)
JP (1) JP3711238B2 (no)
KR (1) KR20010022583A (no)
CN (1) CN1264381A (no)
AP (1) AP9801312A0 (no)
AT (1) ATE296825T1 (no)
AU (1) AU7927498A (no)
BG (1) BG104107A (no)
BR (1) BR9811844A (no)
CA (1) CA2293621C (no)
CO (1) CO4960634A1 (no)
DE (1) DE69830409T2 (no)
EA (1) EA200000098A1 (no)
ES (1) ES2241146T3 (no)
GT (1) GT199800114A (no)
HR (1) HRP980434A2 (no)
HU (1) HUP0002956A3 (no)
ID (1) ID24300A (no)
IL (1) IL133430A0 (no)
IS (1) IS5294A (no)
MA (1) MA24629A1 (no)
NO (1) NO996178L (no)
OA (1) OA11277A (no)
PA (1) PA8456601A1 (no)
PE (1) PE106199A1 (no)
PL (1) PL338575A1 (no)
SA (1) SA98190435A (no)
TN (1) TNSN98148A1 (no)
TR (1) TR200000333T2 (no)
WO (1) WO1999007703A1 (no)
ZA (1) ZA986968B (no)

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PL354982A1 (en) * 1999-09-30 2004-03-22 Neurogen Corporation Amino substituted pyrazolo[1,5,-a]-1,5-pyrimidines and pyrazolo[1,5-a]-1,3,5-triazines
IL150388A0 (en) * 1999-12-24 2002-12-01 Aventis Pharma Ltd Azaindoles
GB0117396D0 (en) 2001-07-17 2001-09-05 Glaxo Group Ltd Chemical compounds
GB0308208D0 (en) 2003-04-09 2003-05-14 Glaxo Group Ltd Chemical compounds
RU2389731C2 (ru) 2004-06-02 2010-05-20 Такеда Фармасьютикал Компани Лимитед Конденсированное гетероциклическое соединение
MXPA06014798A (es) 2004-06-17 2007-06-22 Wyeth Corp Antagonistas del receptor de hormona para liberar gonadotropina.
RU2007101509A (ru) 2004-06-17 2008-07-27 Уайт (Us) Способ получения антагонистов рецепторов гормона, высвобождающего гонадотропин
TW200615268A (en) * 2004-08-02 2006-05-16 Osi Pharm Inc Aryl-amino substituted pyrrolopyrimidine multi-kinase inhibiting compounds
MY179032A (en) 2004-10-25 2020-10-26 Cancer Research Tech Ltd Ortho-condensed pyridine and pyrimidine derivatives (e.g.purines) as protein kinase inhibitors
KR20060087386A (ko) 2005-01-28 2006-08-02 주식회사 대웅제약 신규 벤조이미다졸 유도체 및 이를 함유하는 약제학적조성물
PL1861387T3 (pl) * 2005-01-28 2014-08-29 Dae Woong Pharma Pochodne benzoimidazolu i ich kompozycje farmaceutyczne
US7534796B2 (en) 2005-02-18 2009-05-19 Wyeth Imidazo[4,5-b]pyridine antagonists of gonadotropin releasing hormone receptor
US7538113B2 (en) 2005-02-18 2009-05-26 Wyeth 4-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
US7582634B2 (en) 2005-02-18 2009-09-01 Wyeth 7-substituted imidazo[4,5-c]pyridine antagonists of gonadotropin releasing hormone receptor
EP1877076A4 (en) * 2005-04-15 2012-02-01 Regenertech Pty Ltd USE OF NEUROPEPTIDES Y (NPY) AND AGONIST OF ANTAGONISTS THEREOF FOR REGENERATING TISSUES
US7531542B2 (en) 2005-05-18 2009-05-12 Wyeth Benzooxazole and benzothiazole antagonists of gonadotropin releasing hormone receptor
US7582636B2 (en) 2005-05-26 2009-09-01 Wyeth Piperazinylimidazopyridine and piperazinyltriazolopyridine antagonists of Gonadotropin Releasing Hormone receptor
AU2006267338B2 (en) * 2005-07-13 2012-08-16 Msd K.K. Heterocycle-substituted benzimidazole derivative
AR057525A1 (es) * 2005-10-03 2007-12-05 Astrazeneca Ab Compuestos inhibidores selectivos de gsk3 y un proceso para su preparacion
AR055669A1 (es) * 2005-10-03 2007-08-29 Astrazeneca Ab Derivados de 3h - imidazo[4, 5 -b]piridina como inhibidores selectivos de gsk3, metodos e internediarios para su preparacion, composiciones farmaceuticas que los contienen y su uso para la elaboracion de un medicamento para el tratamiento de enfermedades neurodegenerativas y mentales.
WO2007067537A1 (en) * 2005-12-07 2007-06-14 Osi Pharmaceuticals, Inc. Pyrrolopyridine kinase inhibiting compounds
WO2007072017A2 (en) * 2005-12-22 2007-06-28 The Institute Of Cancer Research Enzyme inhibitors
CA2640672A1 (en) 2006-02-17 2007-08-23 Pfizer Limited 3 -deazapurine derivatives as tlr7 modulators
DK3421471T3 (da) 2006-04-25 2021-06-14 Astex Therapeutics Ltd Purin- og deazapurinderivater som farmaceutiske forbindelser
KR101134239B1 (ko) 2006-07-11 2012-04-10 주식회사 대웅제약 신규한 바이아릴 벤조이미다졸 유도체 및 이를 함유하는 약학 조성물
WO2008007900A1 (en) * 2006-07-11 2008-01-17 Daewoong Pharmaceutical Co., Ltd. Novel biaryl benzoimidazole derivatives and pharmaceutical composition comprising the same
CL2007002617A1 (es) 2006-09-11 2008-05-16 Sanofi Aventis Compuestos derivados de pirrolo[2,3-b]pirazin-6-ilo; composicion farmaceutica que comprende a dichos compuestos; y su uso para tratar inflamacion de las articulaciones, artritis reumatoide, tumores, linfoma de las celulas del manto.
WO2008121064A1 (en) * 2007-03-30 2008-10-09 Astrazeneca Ab New imidazo[4,5-b]pyridine-6-halo-7-aryl/heteroaryl compounds 705
DE102007027800A1 (de) 2007-06-16 2008-12-18 Bayer Healthcare Ag Substituierte bicyclische Heteroaryl-Verbindungen und ihre Verwendung
AU2008309383B2 (en) 2007-10-11 2012-04-19 Astrazeneca Ab Pyrrolo [2, 3 -D] pyrimidin derivatives as protein kinase B inhibitors
WO2009098715A2 (en) 2008-01-11 2009-08-13 Natco Pharma Limited Novel pyrazolo [3, 4 -d] pyrimidine derivatives as anti -cancer agents
SG193505A1 (en) 2011-04-01 2013-10-30 Astrazeneca Ab Therapeutic treatment
AU2012321110B2 (en) 2011-11-30 2014-10-23 Astrazeneca Ab Combination treatment
AU2013204533B2 (en) 2012-04-17 2017-02-02 Astrazeneca Ab Crystalline forms

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DE2818676A1 (de) * 1978-04-27 1979-11-08 Troponwerke Gmbh & Co Kg Substituierte 5,6-dimethylpyrrolo 2,3-d pyrimidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
GB9022644D0 (en) * 1990-10-18 1990-11-28 Ici Plc Heterocyclic compounds
US5877178A (en) * 1991-04-08 1999-03-02 Duquesne University Of The Holy Ghost Pyrimidine derivatives and methods of making and using these derivatives
US5235053A (en) * 1992-06-22 1993-08-10 Eli Lilly And Company Process for the synthesis of 4-hydroxy-5-halopyrrold[2,3-d]pyrimidine intermediates
US5284971A (en) 1992-07-16 1994-02-08 Syntex (U.S.A.) Inc. 4-(3-cyclohexyl-4-hydroxy or-methoxy phenylsulfonyl) 3,5 dibromo phenyl acetic thyromimetic cholesterol-lowering agents
DK0580550T3 (da) 1992-07-21 1998-02-02 Ciba Geigy Ag Oxamidsyrederivater som hypercholesterolæmiske midler
DK0682027T3 (da) * 1994-05-03 1998-05-04 Ciba Geigy Ag Pyrrolopyrimidinderivater med antiproliferativ virkning
AU694801B2 (en) * 1994-09-29 1998-07-30 Novartis Ag Pyrrolo(2,3-d)pyrimidines and their use
US6562862B1 (en) 1994-10-20 2003-05-13 Eli Lilly And Company Methods of inhibiting physiological conditions associated with an excess of neuropeptide Y
BR9509610A (pt) 1994-11-07 1997-10-28 Pfizer Ligandos específicos de neuropeptideo Y1
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EP0759441A3 (en) 1995-06-30 1999-06-30 Eli Lilly And Company Methods of treating neuropeptide Y-associated conditions
JP2000501107A (ja) 1996-01-09 2000-02-02 イーライ・リリー・アンド・カンパニー ベンズイミダゾリル神経ペプチドｙ受容体アンタゴニスト

Also Published As

Publication number Publication date
AP9801312A0 (en) 2000-01-30
WO1999007703A1 (en) 1999-02-18
PL338575A1 (en) 2000-11-06
OA11277A (en) 2003-07-29
CA2293621A1 (en) 1999-02-18
JP2001512729A (ja) 2001-08-28
CN1264381A (zh) 2000-08-23
BR9811844A (pt) 2000-08-08
AU7927498A (en) 1999-03-01
BG104107A (bg) 2000-08-31
HUP0002956A3 (en) 2002-01-28
NO996178L (no) 2000-02-14
IS5294A (is) 1999-12-10
PE106199A1 (es) 1999-11-02
JP3711238B2 (ja) 2005-11-02
IL133430A0 (en) 2001-04-30
SA98190435A (ar) 2005-12-03
ZA986968B (en) 2000-02-04
CA2293621C (en) 2003-12-30
PA8456601A1 (es) 2000-05-24
HUP0002956A2 (hu) 2001-08-28
KR20010022583A (ko) 2001-03-26
DE69830409D1 (de) 2005-07-07
DE69830409T2 (de) 2006-01-26
HRP980434A2 (en) 1999-04-30
EP1003744A1 (en) 2000-05-31
EP1003744B1 (en) 2005-06-01
EA200000098A1 (ru) 2000-08-28
TNSN98148A1 (fr) 2005-03-15
US6187778B1 (en) 2001-02-13
GT199800114A (es) 2000-01-18
CO4960634A1 (es) 2000-09-25
MA24629A1 (fr) 1999-04-01
TR200000333T2 (tr) 2000-05-22
ES2241146T3 (es) 2005-10-16
ATE296825T1 (de) 2005-06-15
ID24300A (id) 2000-07-13

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