ATE340571T1 - Pharmazeutische zubereitungen enthaltend beta- turn peptidomimetische zyklische substanzen - Google Patents
Pharmazeutische zubereitungen enthaltend beta- turn peptidomimetische zyklische substanzenInfo
- Publication number
- ATE340571T1 ATE340571T1 AT01942551T AT01942551T ATE340571T1 AT E340571 T1 ATE340571 T1 AT E340571T1 AT 01942551 T AT01942551 T AT 01942551T AT 01942551 T AT01942551 T AT 01942551T AT E340571 T1 ATE340571 T1 AT E340571T1
- Authority
- AT
- Austria
- Prior art keywords
- trka
- turn
- beta
- extracellular domain
- peptidomimmetic
- Prior art date
Links
- 239000000825 pharmaceutical preparation Substances 0.000 title 1
- 239000000126 substance Substances 0.000 title 1
- 101150111783 NTRK1 gene Proteins 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 4
- 102000007339 Nerve Growth Factor Receptors Human genes 0.000 abstract 2
- 108010032605 Nerve Growth Factor Receptors Proteins 0.000 abstract 2
- 239000003446 ligand Substances 0.000 abstract 2
- 230000001537 neural effect Effects 0.000 abstract 2
- 239000000816 peptidomimetic Substances 0.000 abstract 2
- 102000004022 Protein-Tyrosine Kinases Human genes 0.000 abstract 1
- 108090000412 Protein-Tyrosine Kinases Proteins 0.000 abstract 1
- 239000000556 agonist Substances 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 230000004069 differentiation Effects 0.000 abstract 1
- 239000002831 pharmacologic agent Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 150000003384 small molecules Chemical class 0.000 abstract 1
- 230000008685 targeting Effects 0.000 abstract 1
- 230000001228 trophic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US17648200P | 2000-01-18 | 2000-01-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE340571T1 true ATE340571T1 (de) | 2006-10-15 |
Family
ID=22644525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT01942551T ATE340571T1 (de) | 2000-01-18 | 2001-01-18 | Pharmazeutische zubereitungen enthaltend beta- turn peptidomimetische zyklische substanzen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6881719B2 (de) |
| EP (1) | EP1265605B1 (de) |
| AT (1) | ATE340571T1 (de) |
| AU (1) | AU2001228212A1 (de) |
| CA (1) | CA2397670C (de) |
| DE (1) | DE60123399T2 (de) |
| DK (1) | DK1265605T3 (de) |
| ES (1) | ES2273849T3 (de) |
| WO (1) | WO2001052843A1 (de) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7923216B2 (en) * | 1997-08-14 | 2011-04-12 | Institut Pasteur | In vivo modulation of neuronal transport |
| US7923015B2 (en) | 1997-08-14 | 2011-04-12 | Institut Pasteur | Methods for direct visualization of active synapses |
| US7566765B2 (en) * | 2000-03-06 | 2009-07-28 | Rigel Pharmaceuticals, Inc. | Heterocyclic compounds containing a nine-membered carbon-nitrogen ring |
| AU2002259305A1 (en) | 2001-05-25 | 2002-12-09 | Cornell Research Foundation, Inc. | High affinity ligand for p75 neurotrophin receptor |
| AUPR604401A0 (en) * | 2001-06-29 | 2001-07-26 | University Of Wollongong, The | Peptoid compounds |
| ES2357948T3 (es) | 2002-10-08 | 2011-05-04 | Rinat Neuroscience Corp. | Procedimientos para tratar dolor postquirúrgico mediante la administración de un anticuerpo frente al factor de crecimiento nervioso y composiciones que contienen el mismo. |
| WO2005000194A2 (en) | 2002-10-08 | 2005-01-06 | Rinat Neuroscience Corp. | Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody and compositions containing the same |
| US7569364B2 (en) | 2002-12-24 | 2009-08-04 | Pfizer Inc. | Anti-NGF antibodies and methods using same |
| US9498530B2 (en) | 2002-12-24 | 2016-11-22 | Rinat Neuroscience Corp. | Methods for treating osteoarthritis pain by administering a nerve growth factor antagonist and compositions containing the same |
| CA2511598C (en) | 2002-12-24 | 2016-09-13 | Rinat Neuroscience Corp. | Anti-ngf antibodies and methods using same |
| PL378582A1 (pl) | 2003-03-19 | 2006-05-02 | Biogen Idec Ma Inc. | Białko wiążące receptor Nogo |
| EP2210612B1 (de) | 2003-06-18 | 2016-10-05 | Ocera Therapeutics, Inc. | Makrozyklische Motilin Rezeptorantagonisten |
| ITRM20030601A1 (it) * | 2003-12-24 | 2005-06-25 | Lay Line Genomics Spa | Metodo per l'umanizzazione di anticorpi e anticorpi umanizzati con esso ottenuti. |
| DK2206728T3 (en) | 2004-04-07 | 2018-04-23 | Rinat Neuroscience Corp | METHODS OF TREATING BONE CANCER PAIN BY SUBMITTING A NERVOUS FACTOR-ANTAGONISTIC ANTIBODY |
| EP2474317A1 (de) | 2004-06-24 | 2012-07-11 | Biogen Idec MA Inc. | Behandlung von Zuständen einhergehend mit Demyelisation |
| US8637464B2 (en) | 2004-07-14 | 2014-01-28 | Janssen Pharmaceutica N.V. | P75NTR screening assay |
| EP1810028A2 (de) * | 2004-10-14 | 2007-07-25 | Rigel Pharmaceuticals, Inc. | Heterocyklische inhibitoren von ires-vermittelter translation und verwendungverfahren damit |
| US20110230479A1 (en) * | 2005-04-15 | 2011-09-22 | Longo Frank M | Neurotrophin mimetics and uses thereof |
| US7723328B2 (en) * | 2005-04-15 | 2010-05-25 | The University Of North Carolina At Chapel Hill | Methods of facilitating cell survival using neurotrophin mimetics |
| ITRM20050290A1 (it) * | 2005-06-07 | 2006-12-08 | Lay Line Genomics Spa | Uso di molecole in grado di inibire il legame tra ngf e il suo recettore trka come analgesici ad effetto prolungato. |
| US8686045B2 (en) | 2005-06-08 | 2014-04-01 | The University Of North Carolina At Chapel Hill | Methods of facilitating neural cell survival using non-peptide and peptide BDNF neurotrophin mimetics |
| ES2434470T3 (es) | 2005-07-08 | 2013-12-16 | Biogen Idec Ma Inc. | Anticuerpos SP35 y usos de éstos |
| EP2068866A4 (de) | 2006-07-24 | 2010-04-07 | Biogen Idec Inc | Verfahren zur förderung von myelinisierung, neuronalem überleben und oligodendrozytendifferenzierung mittels verabreichung von sp35- bzw. trka-antagonisten |
| AU2011253937B2 (en) * | 2006-12-05 | 2012-09-27 | The Royal Institution For The Advancement Of Learning/ Mcgill University | Methods of use of TRK receptor modulators |
| CN101657212B (zh) * | 2006-12-05 | 2014-03-19 | 皇家学习促进会/麦吉尔大学 | Trk受体调节剂的使用方法 |
| EP2205071B1 (de) * | 2007-10-11 | 2015-07-22 | Biogen MA Inc. | Lingo-1-antagonisten und trkb-agonisten zur verwendung zur behandlung von glaukom |
| US20110123553A1 (en) * | 2007-11-08 | 2011-05-26 | Biogen Idec Ma Inc. | Use of LINGO-4 Antagonists in the Treatment of Conditions Involving Demyelination |
| EP2271337B1 (de) | 2008-04-04 | 2014-09-03 | Mimetogen Pharmaceuticals Inc. | Beta-turn-peptidomimetische zyklische verbindungen zur behandlung von trockenen augen |
| NZ590605A (en) | 2008-07-09 | 2012-11-30 | Biogen Idec Inc | Compositions comprising antibodies to lingo or fragments thereof |
| CN102333537B (zh) * | 2009-02-27 | 2014-08-13 | 米梅托根药物公司 | 用于治疗色素性视网膜炎的模拟肽环状化合物 |
| US10273219B2 (en) | 2009-11-12 | 2019-04-30 | Pharmatrophix, Inc. | Crystalline forms of neurotrophin mimetic compounds and their salts |
| CN102740856B (zh) | 2009-11-12 | 2015-02-18 | 特罗菲克斯制药股份有限公司 | 神经营养蛋白模拟化合物及其盐的晶型 |
| KR102142161B1 (ko) | 2012-05-14 | 2020-08-06 | 바이오젠 엠에이 인코포레이티드 | 운동 뉴런 관련 병태 치료용 lingo-2 길항제 |
| US9115179B2 (en) | 2012-06-22 | 2015-08-25 | Mimetogen Pharmaceuticals Inc. | Synthesis of beta-turn peptidomimetic cyclic compounds |
| EP2970098B1 (de) | 2013-03-15 | 2020-01-08 | Pharmatrophix Inc. | Nichtpeptidische bdnf-neurotrophin-mimetika |
| AU2014228017B2 (en) | 2013-03-15 | 2018-08-30 | Pharmatrophix, Inc. | Non-peptide BDNF Neurotrophin mimetics |
| US9657059B2 (en) | 2013-09-09 | 2017-05-23 | Canimguide Therapeutics Ab | Immune system modulators |
| US10435467B2 (en) | 2015-01-08 | 2019-10-08 | Biogen Ma Inc. | LINGO-1 antagonists and uses for treatment of demyelinating disorders |
| ES2853582T3 (es) | 2015-03-06 | 2021-09-16 | Canimguide Therapeutics Ab | Moduladores del sistema inmune y composiciones |
| KR102056257B1 (ko) | 2015-07-09 | 2019-12-16 | 미메토젠 파르마슈티칼스 인크. | 베타-턴 펩티도미메틱 사이클릭 염의 용액상 합성 및 결정화 |
| US20230312651A1 (en) * | 2020-07-10 | 2023-10-05 | The University Of Tokyo | Cyclic Peptide, Peptide Complex, and Drug Composition Containing Said Cyclic Peptide and/or Said Peptide Complex |
| AU2022283808A1 (en) * | 2021-06-02 | 2023-12-07 | The Texas A&M University System | Selective small molecule agonists and partial agonists of trk receptors |
| JP2025527299A (ja) * | 2022-08-05 | 2025-08-20 | ザ テキサス エーアンドエム ユニバーシティ システム | 医療用途のための色素結合環化ペプチドのための組成物および方法 |
| FR3148027A1 (fr) * | 2023-04-24 | 2024-10-25 | Peptinov | Composition vaccinale anti-ngf |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5034224A (en) * | 1989-05-30 | 1991-07-23 | American Cyanamid Company | Method and composition for treating protozoal infections |
| DE69110906T2 (de) * | 1990-12-21 | 1995-11-16 | Hsc Research Dev Ltd Partnersh | Verwendung von Wirtszellphospholipiden zur Hemmung bakterieller Besiedlung. |
| GB9402331D0 (en) * | 1994-02-07 | 1994-03-30 | Univ Mcgill | Nerve growth factor structural analogs and their uses |
-
2001
- 2001-01-18 AT AT01942551T patent/ATE340571T1/de not_active IP Right Cessation
- 2001-01-18 AU AU2001228212A patent/AU2001228212A1/en not_active Abandoned
- 2001-01-18 CA CA2397670A patent/CA2397670C/en not_active Expired - Lifetime
- 2001-01-18 EP EP01942551A patent/EP1265605B1/de not_active Expired - Lifetime
- 2001-01-18 DK DK01942551T patent/DK1265605T3/da active
- 2001-01-18 DE DE60123399T patent/DE60123399T2/de not_active Expired - Lifetime
- 2001-01-18 ES ES01942551T patent/ES2273849T3/es not_active Expired - Lifetime
- 2001-01-18 WO PCT/CA2001/000043 patent/WO2001052843A1/en not_active Ceased
- 2001-01-18 US US10/181,546 patent/US6881719B2/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US20030211982A1 (en) | 2003-11-13 |
| CA2397670C (en) | 2010-06-08 |
| WO2001052843A1 (en) | 2001-07-26 |
| EP1265605B1 (de) | 2006-09-27 |
| CA2397670A1 (en) | 2001-07-26 |
| DK1265605T3 (da) | 2007-02-12 |
| DE60123399T2 (de) | 2007-08-23 |
| ES2273849T3 (es) | 2007-05-16 |
| DE60123399D1 (de) | 2006-11-09 |
| EP1265605A1 (de) | 2002-12-18 |
| AU2001228212A1 (en) | 2001-07-31 |
| US6881719B2 (en) | 2005-04-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |