|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
HRP20050089B1
(hr)
|
2002-07-29 |
2015-06-19 |
Rigel Pharmaceuticals |
Upotreba 2,4 pirimidindiaminskog spoja za proizvodnju lijeka za lijeäśenje ili sprjeäśavanje autoimunosne bolesti
|
|
CA2500727A1
(en)
*
|
2002-10-03 |
2004-04-15 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
|
US20050282814A1
(en)
*
|
2002-10-03 |
2005-12-22 |
Targegen, Inc. |
Vasculostatic agents and methods of use thereof
|
|
JP4886511B2
(ja)
*
|
2003-07-30 |
2012-02-29 |
ライジェル ファーマシューティカルズ, インコーポレイテッド |
2,4−ピリミジンジアミン化合物による自己免疫疾患の治療または予防方法
|
|
EP2543376A1
(en)
|
2004-04-08 |
2013-01-09 |
Targegen, Inc. |
Benzotriazine inhibitors of kinases
|
|
AU2005276974B2
(en)
*
|
2004-08-25 |
2012-08-02 |
Targegen, Inc. |
Heterocyclic compounds and methods of use
|
|
CN101115761B
(zh)
|
2005-01-19 |
2012-07-18 |
里格尔药品股份有限公司 |
2,4-嘧啶二胺化合物的前药及其应用
|
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
JP2008543775A
(ja)
*
|
2005-06-08 |
2008-12-04 |
ターゲジェン インコーポレーティッド |
眼の障害を治療するための方法および組成物
|
|
AU2006254840B2
(en)
|
2005-06-08 |
2012-08-02 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
|
US8604042B2
(en)
*
|
2005-11-01 |
2013-12-10 |
Targegen, Inc. |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
|
NZ567851A
(en)
|
2005-11-01 |
2011-09-30 |
Targegen Inc |
Bi-aryl meta-pyrimidine inhibitors of kinases
|
|
US8133900B2
(en)
|
2005-11-01 |
2012-03-13 |
Targegen, Inc. |
Use of bi-aryl meta-pyrimidine inhibitors of kinases
|
|
US20070161645A1
(en)
*
|
2005-11-02 |
2007-07-12 |
Targegen, Inc. |
Thiazole inhibitors targeting resistant kinase mutations
|
|
TWI630207B
(zh)
|
2005-12-13 |
2018-07-21 |
英塞特控股公司 |
作為傑納斯激酶(JANUS KINASE)抑制劑之經雜芳基取代之吡咯并〔2,3-b〕吡啶及吡咯并〔2,3-b〕嘧啶
|
|
ES2622493T3
(es)
|
2006-02-24 |
2017-07-06 |
Rigel Pharmaceuticals, Inc. |
Composiciones y métodos para la inhibición de la ruta de JAK
|
|
US7691858B2
(en)
*
|
2006-04-25 |
2010-04-06 |
Targegen, Inc. |
Kinase inhibitors and methods of use thereof
|
|
WO2008008234A1
(en)
*
|
2006-07-07 |
2008-01-17 |
Targegen, Inc. |
2-amino-5-substituted pyrimidine inhibitors
|
|
EP2222647B1
(en)
|
2006-10-23 |
2015-08-05 |
Cephalon, Inc. |
Fused bicyclic derivatives of 2,4-diaminopyrimidine as alk and c-met inhibitors
|
|
WO2008077810A2
(en)
|
2006-12-22 |
2008-07-03 |
F. Hoffmann-La Roche Ag |
Spiro-piperidine derivatives
|
|
TW200840581A
(en)
*
|
2007-02-28 |
2008-10-16 |
Astrazeneca Ab |
Novel pyrimidine derivatives
|
|
KR20090129434A
(ko)
*
|
2007-03-01 |
2009-12-16 |
수퍼젠, 인크. |
피리미딘-2,4-디아민 유도체 및 jak2 키나제 억제제로서의 이의 용도
|
|
US7947698B2
(en)
|
2007-03-23 |
2011-05-24 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
|
EP3070090B1
(en)
|
2007-06-13 |
2018-12-12 |
Incyte Holdings Corporation |
Use of salts of the janus kinase inhibitor (r)-3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h- pyrazol-1-yl)-3- cyclopentylpropanenitrile
|
|
WO2009010789A2
(en)
*
|
2007-07-16 |
2009-01-22 |
Astrazeneca Ab |
Pyrimidine derivatives 934
|
|
AU2008275918B2
(en)
|
2007-07-17 |
2014-01-30 |
Rigel Pharmaceuticals, Inc. |
Cyclic amine substituted pyrimidinediamines as PKC inhibitors
|
|
MX2010002336A
(es)
|
2007-08-28 |
2010-03-25 |
Irm Llc |
Derivados de 2-bifenil-amino-4-amino-pirimidina como inhibidores de cinasa.
|
|
US8415361B2
(en)
|
2007-11-09 |
2013-04-09 |
The Salk Institute For Biological Studies |
Use of TAM receptor inhibitors as antimicrobials
|
|
WO2009073575A2
(en)
*
|
2007-11-30 |
2009-06-11 |
Oregon Health & Science University |
Methods for treating induced cellular proliferative disorders
|
|
WO2009087127A1
(en)
|
2008-01-11 |
2009-07-16 |
F. Hoffmann-La Roche Ag |
Modulators for amyloid beta
|
|
LT2252300T
(lt)
*
|
2008-02-22 |
2017-02-10 |
Rigel Pharmaceuticals, Inc. |
2,4-pirimidindiaminų panaudojimas aterosklerozės gydymui
|
|
KR101247840B1
(ko)
|
2008-02-22 |
2013-03-26 |
에프. 호프만-라 로슈 아게 |
아밀로이드 베타 조절제
|
|
MX2010012080A
(es)
*
|
2008-05-05 |
2011-04-11 |
Univ Winthrop Hospital |
Metodo para mejorar el perfil de riesgo cardiovascular de los inhibidores de cox.
|
|
MX2010012703A
(es)
|
2008-05-21 |
2010-12-21 |
Ariad Pharma Inc |
Derivados fosforosos como inhibidores de cinasa.
|
|
US9273077B2
(en)
|
2008-05-21 |
2016-03-01 |
Ariad Pharmaceuticals, Inc. |
Phosphorus derivatives as kinase inhibitors
|
|
PE20100087A1
(es)
|
2008-06-25 |
2010-02-08 |
Irm Llc |
Compuestos y composiciones como inhibidores de cinasa
|
|
US8338439B2
(en)
*
|
2008-06-27 |
2012-12-25 |
Celgene Avilomics Research, Inc. |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
SG10201510696RA
(en)
*
|
2008-06-27 |
2016-01-28 |
Celgene Avilomics Res Inc |
Heteroaryl compounds and uses thereof
|
|
US11351168B1
(en)
|
2008-06-27 |
2022-06-07 |
Celgene Car Llc |
2,4-disubstituted pyrimidines useful as kinase inhibitors
|
|
WO2010011349A2
(en)
*
|
2008-07-25 |
2010-01-28 |
Supergen, Inc. |
Pyrimidine-2,4-diamine jak2 kinase inhibiting anti-inflammation use
|
|
CA2732791A1
(en)
*
|
2008-08-05 |
2010-02-11 |
Targegen, Inc. |
Methods of treating thalassemia
|
|
CL2009001884A1
(es)
*
|
2008-10-02 |
2010-05-14 |
Incyte Holdings Corp |
Uso de 3-ciclopentil-3-[4-(7h-pirrolo[2,3-d]pirimidin-4-il)-1h-pirazol-1-il)propanonitrilo, inhibidor de janus quinasa, y uso de una composición que lo comprende para el tratamiento del ojo seco.
|
|
JP5502089B2
(ja)
|
2008-10-09 |
2014-05-28 |
エフ.ホフマン−ラ ロシュ アーゲー |
アミロイドβのモジュレーター
|
|
WO2010052199A1
(en)
|
2008-11-10 |
2010-05-14 |
F. Hoffmann-La Roche Ag |
Heterocyclic gamma secretase modulators
|
|
US20110245156A1
(en)
*
|
2008-12-09 |
2011-10-06 |
Cytokine Pharmasciences, Inc. |
Novel antiviral compounds, compositions, and methods of use
|
|
CA2752150A1
(en)
|
2009-02-11 |
2010-08-19 |
Reaction Biology Corp. |
Selective kinase inhibitors
|
|
WO2010112210A1
(en)
*
|
2009-04-03 |
2010-10-07 |
Cellzome Ag |
Methods for the identification of kinase interacting molecules and for the purification of kinase proteins
|
|
EP2419423A1
(en)
*
|
2009-04-14 |
2012-02-22 |
Cellzome Limited |
Fluoro substituted pyrimidine compounds as jak3 inhibitors
|
|
JP5918693B2
(ja)
|
2009-05-05 |
2016-05-18 |
ダナ ファーバー キャンサー インスティテュート インコーポレイテッド |
Egfr阻害剤及び疾患の治療方法
|
|
AR076550A1
(es)
*
|
2009-05-06 |
2011-06-22 |
Portola Pharm Inc |
Inhibidores de la janus tirosina kinasa (jak)
|
|
EP3643312A1
(en)
|
2009-05-22 |
2020-04-29 |
Incyte Holdings Corporation |
3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors
|
|
AR076794A1
(es)
|
2009-05-22 |
2011-07-06 |
Incyte Corp |
Derivados de n-(hetero)aril-pirrolidina de pirazol-4-il-pirrolo [2,3-d]pirimidinas y pirrol-3-il-pirrolo [2,3-d ]pirimidinas como inhibidores de la quinasa janus y composiciones farmaceuticas que los contienen
|
|
EP2448938B9
(en)
|
2009-06-29 |
2015-06-10 |
Incyte Corporation |
Pyrimidinones as pi3k inhibitors
|
|
JP2012197231A
(ja)
*
|
2009-08-06 |
2012-10-18 |
Oncotherapy Science Ltd |
Ttk阻害作用を有するピリジンおよびピリミジン誘導体
|
|
AR078012A1
(es)
|
2009-09-01 |
2011-10-05 |
Incyte Corp |
Derivados heterociclicos de las pirazol-4-il- pirrolo (2,3-d) pirimidinas como inhibidores de la quinasa janus
|
|
CA2771822C
(en)
*
|
2009-09-04 |
2020-08-11 |
Daniel A. Erlanson |
Bruton's tyrosine kinase inhibitors
|
|
CA2771675A1
(en)
*
|
2009-09-11 |
2011-03-17 |
Cellzome Limited |
Ortho substituted pyrimidine compounds as jak inhibitors
|
|
IN2012DN02534A
(enExample)
|
2009-09-16 |
2015-08-28 |
Avila Therapeutics Inc |
|
|
EA201290147A1
(ru)
*
|
2009-10-15 |
2012-11-30 |
Пфайзер Инк. |
Пирроло[2,3-d]пиримидиновые соединения
|
|
WO2011056739A1
(en)
*
|
2009-11-03 |
2011-05-12 |
Glaxosmithkline Llc |
Compounds and methods
|
|
CN102711474B
(zh)
|
2009-11-03 |
2014-09-10 |
葛兰素史密斯克莱有限责任公司 |
喹唑啉化合物
|
|
WO2011073119A1
(en)
*
|
2009-12-14 |
2011-06-23 |
N.V. Organon |
Mk2 inhibitors
|
|
WO2011075334A1
(en)
|
2009-12-18 |
2011-06-23 |
Pfizer Inc. |
Pyrrolo[2,3-d]pyrimidine compounds
|
|
WO2011075643A1
(en)
|
2009-12-18 |
2011-06-23 |
Incyte Corporation |
Substituted heteroaryl fused derivatives as pi3k inhibitors
|
|
EP2516420B8
(en)
*
|
2009-12-23 |
2018-10-17 |
Medicis Pharmaceutical Corporation |
Aminoalkylpyrimidine derivatives as histamine h4 receptor antagonists
|
|
US20110269244A1
(en)
|
2009-12-30 |
2011-11-03 |
Petter Russell C |
Ligand-directed covalent modification of protein
|
|
SG182351A1
(en)
*
|
2010-01-13 |
2012-08-30 |
Glaxosmithkline Llc |
Compounds and methods
|
|
US8486967B2
(en)
|
2010-02-17 |
2013-07-16 |
Hoffmann-La Roche Inc. |
Heteroaryl substituted piperidines
|
|
EP3050882B1
(en)
|
2010-03-10 |
2018-01-31 |
Incyte Holdings Corporation |
Piperidin-4-yl azetidine derivatives as jak1 inhibitors
|
|
BR112012024585A2
(pt)
|
2010-03-30 |
2016-05-31 |
Novartis Ag |
inibidores de pkc para o tratamento de linfomade células b tendo sinalização do receptor de células b ativas crônicas
|
|
EP2558463A1
(en)
|
2010-04-14 |
2013-02-20 |
Incyte Corporation |
Fused derivatives as i3 inhibitors
|
|
US8981083B2
(en)
|
2010-05-14 |
2015-03-17 |
Dana Farber Cancer Institute, Inc. |
Compositions and methods for treating neoplasia, inflammatory disease and other disorders
|
|
MX373121B
(es)
|
2010-05-14 |
2020-04-30 |
Dana Farber Cancer Inst Inc |
Composiciones y metodos para el tratamiento de leucemia.
|
|
CA2799381A1
(en)
|
2010-05-14 |
2011-11-17 |
Dana-Farber Cancer Institute, Inc. |
Male contraceptive compositions and methods of use
|
|
CN103003264B
(zh)
|
2010-05-21 |
2014-08-06 |
切米利亚股份公司 |
嘧啶衍生物
|
|
SG10201503983QA
(en)
|
2010-05-21 |
2015-06-29 |
Incyte Corp |
Topical Formulation for a JAK Inhibitor
|
|
WO2011149827A1
(en)
*
|
2010-05-24 |
2011-12-01 |
Glaxosmithkline Llc |
Compounds and methods
|
|
MY160734A
(en)
|
2010-08-10 |
2017-03-15 |
Celgene Avilomics Res Inc |
Besylate salt of a btk inhibitor
|
|
WO2012061303A1
(en)
|
2010-11-01 |
2012-05-10 |
Avila Therapeutics, Inc. |
Heteroaryl compounds and uses thereof
|
|
NZ710636A
(en)
|
2010-11-01 |
2017-02-24 |
Celgene Avilomics Res Inc |
Heterocyclic compounds and uses thereof
|
|
WO2012060847A1
(en)
*
|
2010-11-07 |
2012-05-10 |
Targegen, Inc. |
Compositions and methods for treating myelofibrosis
|
|
WO2012064706A1
(en)
|
2010-11-10 |
2012-05-18 |
Avila Therapeutics, Inc. |
Mutant-selective egfr inhibitors and uses thereof
|
|
CN103415515B
(zh)
|
2010-11-19 |
2015-08-26 |
因塞特公司 |
作为jak抑制剂的环丁基取代的吡咯并吡啶和吡咯并嘧啶衍生物
|
|
US9034884B2
(en)
|
2010-11-19 |
2015-05-19 |
Incyte Corporation |
Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as JAK inhibitors
|
|
TW201249844A
(en)
|
2010-12-20 |
2012-12-16 |
Incyte Corp |
N-(1-(substituted-phenyl)ethyl)-9H-purin-6-amines as PI3K inhibitors
|
|
WO2012088266A2
(en)
|
2010-12-22 |
2012-06-28 |
Incyte Corporation |
Substituted imidazopyridazines and benzimidazoles as inhibitors of fgfr3
|
|
WO2012125629A1
(en)
*
|
2011-03-14 |
2012-09-20 |
Incyte Corporation |
Substituted diamino-pyrimidine and diamino-pyridine derivatives as pi3k inhibitors
|
|
CA2830129C
(en)
|
2011-03-24 |
2016-07-19 |
Chemilia Ab |
Novel pyrimidine derivatives
|
|
US9126948B2
(en)
*
|
2011-03-25 |
2015-09-08 |
Incyte Holdings Corporation |
Pyrimidine-4,6-diamine derivatives as PI3K inhibitors
|
|
US9249124B2
(en)
|
2011-03-30 |
2016-02-02 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Aurora kinase inhibitors and methods of making and using thereof
|
|
WO2012135801A1
(en)
|
2011-04-01 |
2012-10-04 |
University Of Utah Research Foundation |
Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors
|
|
ES2759615T3
(es)
*
|
2011-04-01 |
2020-05-11 |
Univ Utah Res Found |
Análogos de N-fenilpirimidina-2-amina sustituidos como inhibidores de la quinasa AXL
|
|
BR112013027734A2
(pt)
|
2011-05-04 |
2017-08-08 |
Ariad Pharma Inc |
compostos para a inibição de proliferação celular em cânceres impulsionados pelo egfr, método e composição farmacêutica
|
|
PE20140832A1
(es)
|
2011-06-20 |
2014-07-14 |
Incyte Corp |
Derivados de azetidinil fenil, piridil o pirazinil carboxamida como inhibidores de jak
|
|
TW201313721A
(zh)
|
2011-08-18 |
2013-04-01 |
Incyte Corp |
作為jak抑制劑之環己基氮雜環丁烷衍生物
|
|
KR102030609B1
(ko)
|
2011-09-02 |
2019-10-11 |
인사이트 홀딩스 코포레이션 |
Pi3k 억제제로서 헤테로시클릴아민
|
|
UA111854C2
(uk)
|
2011-09-07 |
2016-06-24 |
Інсайт Холдінгс Корпорейшн |
Способи і проміжні сполуки для отримання інгібіторів jak
|
|
WO2013059548A1
(en)
|
2011-10-19 |
2013-04-25 |
Sanofi |
Compositions and methods for treating cancer using jak2 inhibitor
|
|
CA2853498A1
(en)
|
2011-10-28 |
2013-05-02 |
Celgene Avilomics Research, Inc. |
Methods of treating a bruton's tyrosine kinase disease or disorder
|
|
CN102429901B
(zh)
*
|
2011-11-03 |
2013-11-06 |
合肥博太医药生物技术发展有限公司 |
吲哚-3-甲醇、二吲哚甲烷及其衍生物在制备防治肾纤维化药物中的应用
|
|
SMT201800571T1
(it)
|
2012-03-15 |
2019-01-11 |
Celgene Car Llc |
Sali di un inibitore di chinasi del recettore del fattore di crescita dell’epidermide
|
|
BR112014022789B1
(pt)
|
2012-03-15 |
2022-04-19 |
Celgene Car Llc |
Formas sólidas de um inibidor de quinase de receptor do fator de crescimento epidérmico, composição farmacêutica e usos do mesmo
|
|
AR090548A1
(es)
|
2012-04-02 |
2014-11-19 |
Incyte Corp |
Azaheterociclobencilaminas biciclicas como inhibidores de pi3k
|
|
AU2013204563B2
(en)
|
2012-05-05 |
2016-05-19 |
Takeda Pharmaceutical Company Limited |
Compounds for inhibiting cell proliferation in EGFR-driven cancers
|
|
TW201406761A
(zh)
|
2012-05-18 |
2014-02-16 |
Incyte Corp |
做爲jak抑制劑之哌啶基環丁基取代之吡咯并吡啶及吡咯并嘧啶衍生物
|
|
US9353087B2
(en)
|
2012-06-08 |
2016-05-31 |
Biogen Ma Inc. |
Inhibitors of Bruton's tyrosine kinase
|
|
AR091273A1
(es)
*
|
2012-06-08 |
2015-01-21 |
Biogen Idec Inc |
Inhibidores de pirimidinil tirosina quinasa
|
|
US9611267B2
(en)
|
2012-06-13 |
2017-04-04 |
Incyte Holdings Corporation |
Substituted tricyclic compounds as FGFR inhibitors
|
|
CA2880896C
(en)
|
2012-06-26 |
2021-11-16 |
Del Mar Pharmaceuticals |
Methods for treating tyrosine-kinase-inhibitor-resistant malignancies in patients with genetic polymorphisms or ahi1 dysregulations or mutations employing dianhydrogalactitol, diacetyldianhydrogalactitol, dibromodulcitol, or analogs or derivatives thereof
|
|
US9388185B2
(en)
|
2012-08-10 |
2016-07-12 |
Incyte Holdings Corporation |
Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
|
|
CA2887465A1
(en)
|
2012-10-04 |
2014-04-10 |
University Of Utah Research Foundation |
Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors
|
|
EP2903972B1
(en)
|
2012-10-04 |
2019-12-04 |
University of Utah Research Foundation |
Substituted n-(3-(pyrimidin-4-yl)phenyl)acrylamide analogs as tyrosine receptor kinase btk inhibitors
|
|
PL2919766T3
(pl)
|
2012-11-15 |
2021-10-04 |
Incyte Holdings Corporation |
Postacie dawkowania ruksolitynibu o przedłużonym uwalnianiu
|
|
US9266892B2
(en)
|
2012-12-19 |
2016-02-23 |
Incyte Holdings Corporation |
Fused pyrazoles as FGFR inhibitors
|
|
US9126950B2
(en)
|
2012-12-21 |
2015-09-08 |
Celgene Avilomics Research, Inc. |
Heteroaryl compounds and uses thereof
|
|
US9561228B2
(en)
|
2013-02-08 |
2017-02-07 |
Celgene Avilomics Research, Inc. |
ERK inhibitors and uses thereof
|
|
CN105189509B
(zh)
|
2013-03-06 |
2017-12-19 |
因赛特公司 |
用于制备jak抑制剂的方法及中间体
|
|
RU2693480C2
(ru)
|
2013-03-14 |
2019-07-03 |
Толеро Фармасьютикалз, Инк. |
Ингибиторы jak2 и alk2 и способы их использования
|
|
US9714946B2
(en)
|
2013-03-14 |
2017-07-25 |
Dana-Farber Cancer Institute, Inc. |
Bromodomain binding reagents and uses thereof
|
|
WO2014151761A1
(en)
*
|
2013-03-15 |
2014-09-25 |
Ariad Pharmaceuticals, Inc. |
Novel choline kinase inhibitors
|
|
US9611283B1
(en)
|
2013-04-10 |
2017-04-04 |
Ariad Pharmaceuticals, Inc. |
Methods for inhibiting cell proliferation in ALK-driven cancers
|
|
US9210831B2
(en)
|
2013-04-15 |
2015-12-08 |
International Business Machines Corporation |
Separable and integrated heat sinks facilitating cooling multi-compnent electronic assembly
|
|
TWI649318B
(zh)
|
2013-04-19 |
2019-02-01 |
英塞特控股公司 |
作為fgfr抑制劑之雙環雜環
|
|
ES2665421T3
(es)
*
|
2013-06-04 |
2018-04-25 |
Acturum Real Estate Ab |
Compuestos de pirimidina y su uso como moduladores de la gamma secretasa
|
|
BR112016001457A2
(pt)
|
2013-07-25 |
2017-08-29 |
Dana Farber Cancer Inst Inc |
Inibidores de fatores de transcrição e usos dos mesmos
|
|
EP3030241A4
(en)
*
|
2013-08-06 |
2019-06-19 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
INHIBITORS OF ACK1 / TNK2.TYROSINE KINASE
|
|
SG10201912203XA
(en)
|
2013-08-07 |
2020-02-27 |
Incyte Corp |
Sustained release dosage forms for a jak1 inhibitor
|
|
US9492471B2
(en)
|
2013-08-27 |
2016-11-15 |
Celgene Avilomics Research, Inc. |
Methods of treating a disease or disorder associated with Bruton'S Tyrosine Kinase
|
|
KR20160072261A
(ko)
|
2013-11-08 |
2016-06-22 |
다나-파버 캔서 인스티튜트 인크. |
브로모도메인 및 엑스트라-말단 (bet) 단백질 저해제를 이용한 암 치료를 위한 조합 요법
|
|
SG11201604595VA
(en)
|
2013-12-11 |
2016-07-28 |
Biogen Ma Inc |
Biaryl compounds useful for the treatment of human diseases in oncology, neurology and immunology
|
|
US9415049B2
(en)
|
2013-12-20 |
2016-08-16 |
Celgene Avilomics Research, Inc. |
Heteroaryl compounds and uses thereof
|
|
WO2015117087A1
(en)
|
2014-01-31 |
2015-08-06 |
Dana-Farber Cancer Institute, Inc. |
Uses of diazepane derivatives
|
|
KR20160111036A
(ko)
|
2014-01-31 |
2016-09-23 |
다나-파버 캔서 인스티튜트 인크. |
디아제판 유도체 및 그의 용도
|
|
MX2016009974A
(es)
|
2014-01-31 |
2016-10-31 |
Dana Farber Cancer Inst Inc |
Derivados de diaminopirimidina bencensulfona y sus usos.
|
|
EP4019518A1
(en)
|
2014-02-28 |
2022-06-29 |
Nimbus Lakshmi, Inc. |
Tyk2 inhibitors and uses thereof
|
|
RU2722179C2
(ru)
|
2014-02-28 |
2020-05-28 |
Тэнша Терапеутикс, Инк. |
Лечение состояний, ассоциированных с гиперинсулинемией
|
|
WO2015184305A1
(en)
|
2014-05-30 |
2015-12-03 |
Incyte Corporation |
TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1
|
|
WO2015191677A1
(en)
|
2014-06-11 |
2015-12-17 |
Incyte Corporation |
Bicyclic heteroarylaminoalkyl phenyl derivatives as pi3k inhibitors
|
|
WO2016022460A1
(en)
|
2014-08-03 |
2016-02-11 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
Potent dual brd4-kinase inhibitors as cancer therapeutics
|
|
WO2016022970A1
(en)
|
2014-08-08 |
2016-02-11 |
Dana-Farber Cancer Institute, Inc. |
Dihydropteridinone derivatives and uses thereof
|
|
EP3177626A4
(en)
|
2014-08-08 |
2017-12-27 |
Dana Farber Cancer Institute, Inc. |
Diazepane derivatives and uses thereof
|
|
EP4578865A3
(en)
|
2014-08-12 |
2025-07-30 |
Monash University |
Lymph directing prodrugs
|
|
US10005760B2
(en)
|
2014-08-13 |
2018-06-26 |
Celgene Car Llc |
Forms and compositions of an ERK inhibitor
|
|
TWI679205B
(zh)
*
|
2014-09-02 |
2019-12-11 |
日商日本新藥股份有限公司 |
吡唑并噻唑化合物及醫藥
|
|
US10851105B2
(en)
|
2014-10-22 |
2020-12-01 |
Incyte Corporation |
Bicyclic heterocycles as FGFR4 inhibitors
|
|
UA122130C2
(uk)
|
2014-10-27 |
2020-09-25 |
Тенша Терапеутікс, Інк. |
Інгібітори бромодомену
|
|
CN107076638B
(zh)
|
2014-10-28 |
2019-10-25 |
康明斯排放处理公司 |
Scr转化效率诊断
|
|
RS61853B1
(sr)
|
2014-10-29 |
2021-06-30 |
Bicyclerd Ltd |
Biciklični peptidni ligandi specifični za mt1-mmp
|
|
AU2016219822B2
(en)
|
2015-02-20 |
2020-07-09 |
Incyte Holdings Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
|
WO2016134294A1
(en)
|
2015-02-20 |
2016-08-25 |
Incyte Corporation |
Bicyclic heterocycles as fgfr4 inhibitors
|
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
|
TWI788655B
(zh)
|
2015-02-27 |
2023-01-01 |
美商林伯士拉克許米公司 |
酪胺酸蛋白質激酶2(tyk2)抑制劑及其用途
|
|
DK3831833T3
(da)
|
2015-02-27 |
2022-11-14 |
Incyte Holdings Corp |
Fremgangsmåder til fremstillingen af en pi3k-inhibitor
|
|
US9732097B2
(en)
|
2015-05-11 |
2017-08-15 |
Incyte Corporation |
Process for the synthesis of a phosphoinositide 3-kinase inhibitor
|
|
WO2016183063A1
(en)
|
2015-05-11 |
2016-11-17 |
Incyte Corporation |
Crystalline forms of a pi3k inhibitor
|
|
US10702527B2
(en)
|
2015-06-12 |
2020-07-07 |
Dana-Farber Cancer Institute, Inc. |
Combination therapy of transcription inhibitors and kinase inhibitors
|
|
WO2017004134A1
(en)
|
2015-06-29 |
2017-01-05 |
Nimbus Iris, Inc. |
Irak inhibitors and uses thereof
|
|
RU2732576C2
(ru)
*
|
2015-07-21 |
2020-09-21 |
Гуанчжоу Максиновел Фармасьютикалс Ко., Лтд. |
Пиримидиновое соединение с конденсированными кольцами, его промежуточное соединение, способ получения, композиция и применение
|
|
JP6802263B2
(ja)
|
2015-09-02 |
2020-12-16 |
ニンバス ラクシュミ, インコーポレイテッド |
Tyk2阻害剤およびその使用
|
|
JP7118888B2
(ja)
|
2015-09-08 |
2022-08-16 |
モナッシュ ユニバーシティ |
リンパ指向性プロドラッグ
|
|
JP2018526424A
(ja)
|
2015-09-11 |
2018-09-13 |
ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド |
アセトアミドチエノトリアゾロジアゼピンおよびこれらの使用
|
|
WO2017044720A1
(en)
|
2015-09-11 |
2017-03-16 |
Navitor Pharmaceuticals, Inc. |
Rapamycin analogs and uses thereof
|
|
US11306105B2
(en)
|
2015-09-11 |
2022-04-19 |
Dana-Farber Cancer Institute, Inc. |
Cyano thienotriazolodiazepines and uses thereof
|
|
US10738016B2
(en)
|
2015-10-13 |
2020-08-11 |
H. Lee Moffitt Cancer Center And Research Institute, Inc. |
BRD4-kinase inhibitors as cancer therapeutics
|
|
SI3364958T1
(sl)
|
2015-10-23 |
2023-05-31 |
Navitor Pharmaceuticals, Inc. |
Modulatorji interakcije sestrina in gator2 ter njihova uporaba
|
|
US10045981B2
(en)
|
2015-11-24 |
2018-08-14 |
Jakpharm, Llc |
Selective kinase inhibitors
|
|
CR20180336A
(es)
|
2015-11-25 |
2018-08-06 |
Dana Farber Cancer Inst Inc |
Inhibidores de bromodominio bivalentes y usos de los mismos
|
|
GB201521919D0
(en)
|
2015-12-11 |
2016-01-27 |
Electrophoretics Ltd |
Isobaric mass labels
|
|
EP3389664A4
(en)
|
2015-12-14 |
2020-01-08 |
Raze Therapeutics Inc. |
MTHFD2 CAFFEIN INHIBITORS AND USES THEREOF
|
|
EP4234552A3
(en)
|
2016-03-09 |
2023-10-18 |
Raze Therapeutics, Inc. |
3-phosphoglycerate dehydrogenase inhibitors and uses thereof
|
|
PL3884939T3
(pl)
|
2016-03-09 |
2024-02-26 |
Raze Therapeutics, Inc. |
Inhibitory dehydrogenazy 3-fosfoglicerynianowej i ich zastosowania
|
|
US11337969B2
(en)
|
2016-04-08 |
2022-05-24 |
X4 Pharmaceuticals, Inc. |
Methods for treating cancer
|
|
KR102571679B1
(ko)
*
|
2016-04-15 |
2023-08-29 |
에피자임, 인코포레이티드 |
Ehmt1 및 ehmt2 저해제로서의 아민-치환된 아릴 또는 헤테로아릴 화합물
|
|
US10988465B2
(en)
|
2016-06-21 |
2021-04-27 |
X4 Pharmaceuticals, Inc. |
CXCR4 inhibitors and uses thereof
|
|
JP7054529B2
(ja)
|
2016-06-21 |
2022-04-14 |
エックス4 ファーマシューティカルズ, インコーポレイテッド |
Cxcr4阻害剤およびその使用
|
|
US11332470B2
(en)
|
2016-06-21 |
2022-05-17 |
X4 Pharmaceuticals, Inc. |
CXCR4 inhibitors and uses thereof
|
|
JP7214632B2
(ja)
|
2016-07-21 |
2023-01-30 |
バイオジェン エムエー インク. |
ブルトン型チロシンキナーゼ阻害剤のコハク酸塩形態および組成物
|
|
CN115448916A
(zh)
|
2016-10-14 |
2022-12-09 |
林伯士拉克许米公司 |
Tyk2抑制剂及其用途
|
|
AU2017345736B2
(en)
|
2016-10-21 |
2022-04-07 |
Takeda Pharmaceutical Company Limited |
TYK2 inhibitors and uses thereof
|
|
WO2018089499A1
(en)
|
2016-11-08 |
2018-05-17 |
Navitor Pharmaceuticals, Inc. |
PHENYL AMINO PIPERIDINE mTORC INHIBITORS AND USES THEREOF
|
|
WO2018102397A1
(en)
|
2016-11-29 |
2018-06-07 |
PureTech Health LLC |
Exosomes for delivery of therapeutic agents
|
|
US11091451B2
(en)
|
2016-12-05 |
2021-08-17 |
Raze Therapeutics, Inc. |
SHMT inhibitors and uses thereof
|
|
US11730819B2
(en)
|
2016-12-23 |
2023-08-22 |
Bicycletx Limited |
Peptide derivatives having novel linkage structures
|
|
WO2018127699A1
(en)
|
2017-01-06 |
2018-07-12 |
Bicyclerd Limited |
Compounds for treating cancer
|
|
CA3055209A1
(en)
|
2017-03-08 |
2018-09-13 |
Nimbus Lakshmi, Inc. |
Tyk2 inhibitors, uses, and methods for production thereof
|
|
EP3375778A1
(en)
|
2017-03-14 |
2018-09-19 |
Artax Biopharma Inc. |
Aryl-piperidine derivatives
|
|
EP3375784A1
(en)
|
2017-03-14 |
2018-09-19 |
Artax Biopharma Inc. |
Aza-dihydro-acridone derivatives
|
|
US10342766B2
(en)
*
|
2017-03-23 |
2019-07-09 |
North Carolina Agricultural And Technical State University |
6-shogaol derivatives and activities thereof
|
|
WO2018191146A1
(en)
|
2017-04-10 |
2018-10-18 |
Navitor Pharmaceuticals, Inc. |
Heteroaryl rheb inhibitors and uses thereof
|
|
CN118021814A
(zh)
|
2017-04-21 |
2024-05-14 |
Epizyme股份有限公司 |
用ehmt2抑制剂进行的组合疗法
|
|
ES3040534T3
(en)
|
2017-04-26 |
2025-11-03 |
Navitor Pharm Inc |
Modulator of sestrin-gator2 interaction for use in the treatment of treatment-resistant depression
|
|
EP3615550A1
(en)
|
2017-04-27 |
2020-03-04 |
BicycleTx Limited |
Bicyclic peptide ligands and uses thereof
|
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
|
EP3645549A1
(en)
|
2017-06-26 |
2020-05-06 |
BicycleRD Limited |
Bicyclic peptide ligands with detectable moieties and uses thereof
|
|
JP7216705B2
(ja)
|
2017-07-28 |
2023-02-02 |
ニンバス ラクシュミ, インコーポレイテッド |
Tyk2阻害剤およびその使用方法
|
|
JP7670481B2
(ja)
|
2017-08-04 |
2025-04-30 |
バイスクルテクス・リミテッド |
Cd137に対して特異的な二環式ペプチドリガンド
|
|
US20200283482A1
(en)
|
2017-08-14 |
2020-09-10 |
Bicyclerd Limited |
Bicyclic peptide ligand prr-a conjugates and uses thereof
|
|
US20200291096A1
(en)
|
2017-08-14 |
2020-09-17 |
Bicyclerd Limited |
Bicyclic peptide ligand sting conjugates and uses thereof
|
|
US11883497B2
(en)
|
2017-08-29 |
2024-01-30 |
Puretech Lyt, Inc. |
Lymphatic system-directing lipid prodrugs
|
|
EP3675838A4
(en)
|
2017-08-29 |
2021-04-21 |
PureTech LYT, Inc. |
LIPID PRODRUGS DIRECTED TO THE LYMPHATIC SYSTEM
|
|
US11358948B2
(en)
|
2017-09-22 |
2022-06-14 |
Kymera Therapeutics, Inc. |
CRBN ligands and uses thereof
|
|
WO2019060742A1
(en)
|
2017-09-22 |
2019-03-28 |
Kymera Therapeutics, Inc |
AGENTS FOR DEGRADING PROTEINS AND USES THEREOF
|
|
AU2018353122B2
(en)
*
|
2017-10-18 |
2023-11-23 |
Epizyme, Inc. |
Amine-substituted heterocyclic compounds as EHMT2 inhibitors, salts thereof, and methods of synthesis thereof
|
|
WO2019113487A1
(en)
|
2017-12-08 |
2019-06-13 |
Incyte Corporation |
Low dose combination therapy for treatment of myeloproliferative neoplasms
|
|
WO2019126378A1
(en)
|
2017-12-19 |
2019-06-27 |
Ariya Therapeutics, Inc. |
Lipid prodrugs of mycophenolic acid and uses thereof
|
|
TWI825046B
(zh)
|
2017-12-19 |
2023-12-11 |
英商拜西可泰克斯有限公司 |
Epha2特用之雙環胜肽配位基
|
|
US11304954B2
(en)
|
2017-12-19 |
2022-04-19 |
Puretech Lyt, Inc. |
Lipid prodrugs of mycophenolic acid and uses thereof
|
|
GB201721265D0
(en)
|
2017-12-19 |
2018-01-31 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for EphA2
|
|
US11608345B1
(en)
|
2017-12-19 |
2023-03-21 |
Puretech Lyt, Inc. |
Lipid prodrugs of rapamycin and its analogs and uses thereof
|
|
IL315310A
(en)
|
2017-12-26 |
2024-10-01 |
Kymera Therapeutics Inc |
Irak degraders and uses thereof
|
|
WO2019140387A1
(en)
|
2018-01-12 |
2019-07-18 |
Kymera Therapeutics, Inc. |
Crbn ligands and uses thereof
|
|
US11485743B2
(en)
|
2018-01-12 |
2022-11-01 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
CN109232440B
(zh)
*
|
2018-01-16 |
2020-09-11 |
深圳市塔吉瑞生物医药有限公司 |
用于抑制激酶活性的二苯氨基嘧啶类化合物
|
|
JP7229257B2
(ja)
|
2018-01-29 |
2023-02-28 |
メルク パテント ゲーエムベーハー |
Gcn2阻害剤およびその使用
|
|
KR20200115620A
(ko)
|
2018-01-29 |
2020-10-07 |
메르크 파텐트 게엠베하 |
Gcn2 억제제 및 이의 용도
|
|
EP3746429B1
(en)
|
2018-01-30 |
2022-03-09 |
Incyte Corporation |
Processes for preparing (1-(3-fluoro-2-(trifluoromethyl)isonicotinyl)piperidine-4-one)
|
|
EP3746430A4
(en)
*
|
2018-02-02 |
2021-11-03 |
Padforward LLC |
INHIBITORS OF PROTEIN ARGININE DEIMINASES
|
|
KR20200128518A
(ko)
|
2018-02-23 |
2020-11-13 |
바이사이클티엑스 리미티드 |
다량체성 비사이클릭 펩타이드 리간드
|
|
US10696663B2
(en)
|
2018-02-27 |
2020-06-30 |
Artax Biopharma Inc. |
Chromene derivatives as inhibitors of TCR-NCK interaction
|
|
PT3773593T
(pt)
|
2018-03-30 |
2024-06-25 |
Incyte Corp |
Tratamento da hidradenite supurativa com inibidores de jak
|
|
EP3773591A4
(en)
|
2018-04-05 |
2021-12-22 |
Sumitomo Dainippon Pharma Oncology, Inc. |
AXL KINASE INHIBITORS AND THEIR USE
|
|
KR102063155B1
(ko)
|
2018-04-11 |
2020-01-08 |
한국과학기술연구원 |
우수한 카이네이즈 저해 활성을 보이는 다양한 치환기를 갖는 피리미딘 유도체
|
|
EP4043460B1
(en)
|
2018-04-24 |
2024-06-05 |
Merck Patent GmbH |
Antiproliferation compounds and uses thereof
|
|
ES2969982T3
(es)
|
2018-04-24 |
2024-05-23 |
Vertex Pharma |
Compuestos de pteridinona y usos de los mismos
|
|
TW201946630A
(zh)
|
2018-05-04 |
2019-12-16 |
美商英塞特公司 |
Fgfr抑制劑之鹽
|
|
ES2991427T3
(es)
|
2018-05-04 |
2024-12-03 |
Incyte Corp |
Formas sólidas de un inhibidor de FGFR y procedimientos para preparar las mismas
|
|
CN119258070A
(zh)
|
2018-06-01 |
2025-01-07 |
因赛特公司 |
治疗pi3k相关病症的给药方案
|
|
BR112020025283A2
(pt)
|
2018-06-15 |
2021-03-09 |
Navitor Pharmaceuticals, Inc. |
Análogos de rapamicina e usos dos mesmos
|
|
GB201810316D0
(en)
|
2018-06-22 |
2018-08-08 |
Bicyclerd Ltd |
Peptide ligands for binding to EphA2
|
|
US11180531B2
(en)
|
2018-06-22 |
2021-11-23 |
Bicycletx Limited |
Bicyclic peptide ligands specific for Nectin-4
|
|
WO2020010227A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Protein degraders and uses thereof
|
|
WO2020010177A1
(en)
|
2018-07-06 |
2020-01-09 |
Kymera Therapeutics, Inc. |
Tricyclic crbn ligands and uses thereof
|
|
CA3103995A1
(en)
|
2018-07-26 |
2020-01-30 |
Sumitomo Dainippon Pharma Oncology, Inc. |
Methods for treating diseases associated with abnormal acvr1 expression and acvr1 inhibitors for use in the same
|
|
US10548889B1
(en)
|
2018-08-31 |
2020-02-04 |
X4 Pharmaceuticals, Inc. |
Compositions of CXCR4 inhibitors and methods of preparation and use
|
|
US12030875B2
(en)
|
2018-09-07 |
2024-07-09 |
PIC Therapeutics, Inc. |
EIF4E inhibitors and uses thereof
|
|
KR20250164332A
(ko)
|
2018-09-25 |
2025-11-24 |
임팩트 바이오메디신스, 인코포레이티드 |
골수증식성 장애를 치료하는 방법
|
|
US11414431B2
(en)
|
2018-10-15 |
2022-08-16 |
Nimbus Lakshmi, Inc. |
Substituted pyrazolo[1,5-a]pyrimidines as TYK2 inhibitors
|
|
CN112955459A
(zh)
|
2018-10-23 |
2021-06-11 |
拜斯科技术开发有限公司 |
双环肽配体和其用途
|
|
CA3117336A1
(en)
|
2018-10-24 |
2020-04-30 |
Navitor Pharmaceuticals, Inc. |
Polymorphs of (s)-2-amino-5,5-difluoro-4,4-dimethylpentanoic acid for use in modulating mtorc1
|
|
WO2020092015A1
(en)
|
2018-11-02 |
2020-05-07 |
University Of Rochester |
Therapeutic mitigation of epithelial infection
|
|
CA3120866A1
(en)
|
2018-11-30 |
2020-06-04 |
Nimbus Lakshmi, Inc. |
Tyk2 inhibitors and uses thereof
|
|
CA3119773A1
(en)
|
2018-11-30 |
2020-06-04 |
Kymera Therapeutics, Inc. |
Irak degraders and uses thereof
|
|
GB201820325D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for psma
|
|
GB201820295D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicyclerd Ltd |
Bicyclic peptide ligands specific for MT1-MMP
|
|
GB201820288D0
(en)
|
2018-12-13 |
2019-01-30 |
Bicycle Tx Ltd |
Bicycle peptide ligaands specific for MT1-MMP
|
|
EP3670659A1
(en)
|
2018-12-20 |
2020-06-24 |
Abivax |
Biomarkers, and uses in treatment of viral infections, inflammations, or cancer
|
|
WO2020128527A1
(en)
|
2018-12-21 |
2020-06-25 |
Bicyclerd Limited |
Bicyclic peptide ligands specific for pd-l1
|
|
CN113474045A
(zh)
|
2018-12-21 |
2021-10-01 |
拜斯科技术开发有限公司 |
Pd-l1特异性的双环肽配体
|
|
CN111362922A
(zh)
*
|
2018-12-26 |
2020-07-03 |
上海喆邺生物科技有限公司 |
2,4-二氨基嘧啶衍生物及其用途
|
|
US11174264B2
(en)
|
2019-01-23 |
2021-11-16 |
Nimbus Lakshmi, Inc. |
TYK2 inhibitors and uses thereof
|
|
WO2020167845A1
(en)
|
2019-02-12 |
2020-08-20 |
Impact Biomedicines, Inc. |
Crystalline forms of a jak2 inhibitor
|
|
FR3092581A1
(fr)
*
|
2019-02-12 |
2020-08-14 |
Impact Biomedicines, Inc |
Formes cristallines d'un inhibiteur de jak2
|
|
WO2020165600A1
(en)
|
2019-02-14 |
2020-08-20 |
Bicycletx Limited |
Bicyclic peptide ligand sting conjugates and uses thereof
|
|
US11628162B2
(en)
|
2019-03-08 |
2023-04-18 |
Incyte Corporation |
Methods of treating cancer with an FGFR inhibitor
|
|
US12187722B2
(en)
*
|
2019-03-15 |
2025-01-07 |
The General Hospital Corporation |
Small molecule inhibitors of TEAD transcription factors
|
|
AU2020253990A1
(en)
|
2019-04-02 |
2021-10-28 |
Bicycletx Limited |
Bicycle toxin conjugates and uses thereof
|
|
JP2022527114A
(ja)
|
2019-04-05 |
2022-05-30 |
カイメラ セラピューティクス, インコーポレイテッド |
分解剤およびそれらの使用
|
|
TW202108559A
(zh)
|
2019-05-31 |
2021-03-01 |
美商醫肯納腫瘤學公司 |
Tead抑制劑及其用途
|
|
US12521438B2
(en)
|
2019-06-10 |
2026-01-13 |
Kymera Therapeutics, Inc. |
SMARCA degraders and uses thereof
|
|
WO2021091535A1
(en)
|
2019-11-05 |
2021-05-14 |
Constellation Pharmaceuticals, Inc. |
Treating myeloproliferative disorders with cpi-0610 and a jak inhibitor
|
|
WO2020256739A1
(en)
|
2019-06-21 |
2020-12-24 |
Constellation Pharmaceuticals, Inc. |
Methods of treating myeloproliferative disorders
|
|
WO2020257644A1
(en)
|
2019-06-21 |
2020-12-24 |
Constellation Pharmaceuticals, Inc. |
Methods of treating myeloproliferative disorders
|
|
MX2021015995A
(es)
|
2019-06-28 |
2022-03-11 |
Kymera Therapeutics Inc |
Degradadores de cinasas asociadas al receptor de interleucina-1 (irak) y usos de los mismos.
|
|
WO2021007269A1
(en)
|
2019-07-09 |
2021-01-14 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
US12558427B2
(en)
|
2019-07-17 |
2026-02-24 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
|
TWI862640B
(zh)
|
2019-07-30 |
2024-11-21 |
英商拜西可泰克斯有限公司 |
異質雙環肽複合物
|
|
JP2022548594A
(ja)
|
2019-09-11 |
2022-11-21 |
ビンシア・バイオサイエンシーズ・インコーポレイテッド |
Usp30阻害剤及びその使用
|
|
CN119874700A
(zh)
|
2019-09-13 |
2025-04-25 |
林伯士萨顿公司 |
Hpk1拮抗剂和其用途
|
|
US20220372135A1
(en)
|
2019-09-27 |
2022-11-24 |
Disc Medicine, Inc. |
Methods for treating myelofibrosis and related conditions
|
|
WO2021067374A1
(en)
|
2019-10-01 |
2021-04-08 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
GEAP202415945A
(en)
|
2019-10-14 |
2024-04-25 |
Incyte Corp |
Bicyclic heterocycles as fgfr inhibitors
|
|
WO2021076728A1
(en)
|
2019-10-16 |
2021-04-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
US11306062B2
(en)
|
2019-10-29 |
2022-04-19 |
Johnson Matthey Public Limited |
Forms of fedratinib dihydrochloride
|
|
IL292612A
(en)
|
2019-11-01 |
2022-07-01 |
Navitor Pharm Inc |
Treatment methods using mtorc1 modulator
|
|
CA3163875A1
(en)
|
2019-12-04 |
2021-06-10 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
AU2020395185A1
(en)
|
2019-12-04 |
2022-06-02 |
Incyte Corporation |
Derivatives of an FGFR inhibitor
|
|
AU2020397938A1
(en)
|
2019-12-05 |
2022-06-23 |
Janssen Pharmaceutica Nv |
Rapamycin analogs and uses thereof
|
|
US12551564B2
(en)
|
2019-12-10 |
2026-02-17 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
|
US11591332B2
(en)
|
2019-12-17 |
2023-02-28 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
|
CN115052627A
(zh)
|
2019-12-17 |
2022-09-13 |
凯麦拉医疗公司 |
Irak降解剂和其用途
|
|
BR112022012410A2
(pt)
|
2019-12-23 |
2022-08-30 |
Kymera Therapeutics Inc |
Degradadores smarca e usos dos mesmos
|
|
US12569485B2
(en)
|
2019-12-23 |
2026-03-10 |
Kymera Therapeutics, Inc. |
SMARCA inhibitors and uses thereof
|
|
WO2021146424A1
(en)
|
2020-01-15 |
2021-07-22 |
Incyte Corporation |
Bicyclic heterocycles as fgfr inhibitors
|
|
CN111423419B
(zh)
*
|
2020-01-17 |
2021-12-17 |
温州医科大学 |
一种小分子化合物cyy-260及其在制备抗肿瘤药物中的应用
|
|
CA3166908A1
(en)
|
2020-02-05 |
2021-08-12 |
Daniel Kenneth BONNER |
Lipid prodrugs of neurosteroids
|
|
AU2021230289A1
(en)
|
2020-03-03 |
2022-09-29 |
PIC Therapeutics, Inc. |
eIF4E inhibitors and uses thereof
|
|
MX2022011602A
(es)
|
2020-03-19 |
2023-01-04 |
Kymera Therapeutics Inc |
Degradadores de la proteína de homólogo de ratón de minuto 2 (mdm2) y usos de los mismos.
|
|
CA3177830A1
(en)
|
2020-05-13 |
2021-11-18 |
Maria BECONI |
Anti-hemojuvelin (hjv) antibodies for treating myelofibrosis
|
|
TW202210483A
(zh)
|
2020-06-03 |
2022-03-16 |
美商凱麥拉醫療公司 |
Irak降解劑之結晶型
|
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
|
EP4161521A4
(en)
|
2020-06-03 |
2024-07-10 |
Kymera Therapeutics, Inc. |
DEUTERED IRAQ DEGRADERS AND USES THEREOF
|
|
CN113754591B
(zh)
*
|
2020-06-05 |
2024-01-05 |
山东大学 |
一种hdac、jak和bet三靶点抑制剂及其制备方法和应用
|
|
EP3944859A1
(en)
|
2020-07-30 |
2022-02-02 |
Assistance Publique Hôpitaux de Paris |
Method for treating immune toxicities induced by immune checkpoint inhibitors
|
|
KR20230074119A
(ko)
|
2020-08-03 |
2023-05-26 |
바이사이클티엑스 리미티드 |
펩타이드 기반 링커
|
|
EP4196792A1
(en)
|
2020-08-17 |
2023-06-21 |
BicycleTX Limited |
Bicycle conjugates specific for nectin-4 and uses thereof
|
|
CN112225703B
(zh)
*
|
2020-09-28 |
2022-03-11 |
广州智睿医药科技有限公司 |
一种治疗或预防与lrrk2激酶或异常lrrk2突变激酶活性相关疾病的药物
|
|
EP4232425A4
(en)
|
2020-10-23 |
2024-07-24 |
Nimbus Clotho, Inc. |
Ctps1 inhibitors and uses thereof
|
|
KR20230091150A
(ko)
*
|
2020-10-29 |
2023-06-22 |
수저우 야바오 파마슈티걸 알앤디 컴퍼니 리미티드 |
치환된 디아릴아민 화합물 및 이의 약학적 조성물, 제조 방법과 용도
|
|
TWI750905B
(zh)
*
|
2020-11-19 |
2021-12-21 |
財團法人國家衛生研究院 |
噻唑化合物作為蛋白質激酶抑制劑
|
|
CN117015531A
(zh)
|
2020-12-02 |
2023-11-07 |
医肯纳肿瘤学公司 |
Tead抑制剂及其用途
|
|
WO2022120353A1
(en)
|
2020-12-02 |
2022-06-09 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
TW202237119A
(zh)
|
2020-12-10 |
2022-10-01 |
美商住友製藥腫瘤公司 |
Alk﹘5抑制劑和彼之用途
|
|
AU2021401681A1
(en)
|
2020-12-16 |
2023-06-22 |
Impact Biomedicines, Inc. |
Dosing of fedratinib
|
|
WO2022143628A1
(zh)
*
|
2020-12-29 |
2022-07-07 |
上海岸阔医药科技有限公司 |
预防或治疗抗肿瘤剂相关疾病或病症的方法
|
|
CA3202360A1
(en)
|
2020-12-30 |
2022-07-07 |
Nello Mainolfi |
Irak degraders and uses thereof
|
|
CN112778282B
(zh)
*
|
2021-01-06 |
2022-07-22 |
温州医科大学 |
一种嘧啶类小分子化合物及其应用
|
|
MX2023009059A
(es)
|
2021-02-02 |
2023-09-15 |
Liminal Biosciences Ltd |
Antagonistas de gpr84 y usos de estos.
|
|
CN117098757A
(zh)
|
2021-02-02 |
2023-11-21 |
里米诺生物科学有限公司 |
Gpr84拮抗剂和其用途
|
|
US12252488B2
(en)
|
2021-02-12 |
2025-03-18 |
Nimbus Saturn, Inc. |
HPK1 antagonists and uses thereof
|
|
US11773103B2
(en)
|
2021-02-15 |
2023-10-03 |
Kymera Therapeutics, Inc. |
IRAK4 degraders and uses thereof
|
|
CA3207049A1
(en)
|
2021-02-15 |
2022-08-18 |
Jared Gollob |
Irak4 degraders and uses thereof
|
|
KR20230148208A
(ko)
|
2021-02-25 |
2023-10-24 |
임팩트 바이오메디신스, 인코포레이티드 |
골수섬유증과 같은 혈액 악성종양을 치료하기 위한 bet 억제제 단독 또는 페드라티닙 또는 룩솔리티닙과의 조합물의 용도
|
|
US11926625B2
(en)
|
2021-03-05 |
2024-03-12 |
Nimbus Saturn, Inc. |
HPK1 antagonists and uses thereof
|
|
CN117355304A
(zh)
*
|
2021-03-26 |
2024-01-05 |
住友制药肿瘤公司 |
Alk-5抑制剂及其用途
|
|
WO2022203466A1
(ko)
*
|
2021-03-26 |
2022-09-29 |
주식회사 스탠다임 |
Lrrk2에 대해 저해 활성을 갖는 신규한 페닐아미노피리미딘 화합물 및 이의 용도
|
|
US20240197729A1
(en)
*
|
2021-03-26 |
2024-06-20 |
Sumitomo Pharma Oncology, Inc. |
ALK-5 Inhibitors and Uses Thereof
|
|
JP2024513011A
(ja)
|
2021-03-29 |
2024-03-21 |
ニンバス サターン, インコーポレイテッド |
Hpk1アンタゴニスト及びその使用
|
|
US12325697B2
(en)
|
2021-04-09 |
2025-06-10 |
Nimbus Clio, Inc. |
CBL-B modulators and uses thereof
|
|
EP4323405A1
(en)
|
2021-04-12 |
2024-02-21 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a nectin-4 targeting agent
|
|
KR20230172548A
(ko)
|
2021-04-16 |
2023-12-22 |
이케나 온콜로지, 인코포레이티드 |
Mek 억제제 및 이의 용도
|
|
KR20240020735A
(ko)
|
2021-05-07 |
2024-02-15 |
카이메라 쎄라퓨틱스 인코포레이티드 |
Cdk2 분해제 및 그 용도
|
|
AR126101A1
(es)
|
2021-06-09 |
2023-09-13 |
Incyte Corp |
Heterociclos tricíclicos como inhibidores de fgfr
|
|
CA3220274A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
|
CN118019739A
(zh)
|
2021-08-25 |
2024-05-10 |
皮克医疗公司 |
Eif4e抑制剂及其用途
|
|
JP2024534127A
(ja)
|
2021-08-25 |
2024-09-18 |
ピク セラピューティクス, インコーポレイテッド |
eIF4E阻害剤及びその使用
|
|
US20240358722A1
(en)
|
2021-09-14 |
2024-10-31 |
Impact Biomedicines, Inc. |
Methods of administering fedratinib
|
|
EP4401735A4
(en)
*
|
2021-09-16 |
2025-07-16 |
Lomond Therapeutics Inc |
COMPOUNDS COMPRISING N-ARYLPYRIMIDIN-2-AMINE DERIVATIVES AS THERAPEUTIC AGENTS
|
|
CA3236265A1
(en)
|
2021-10-29 |
2023-05-04 |
William Leong |
Irak4 degraders and synthesis thereof
|
|
WO2023114984A1
(en)
|
2021-12-17 |
2023-06-22 |
Ikena Oncology, Inc. |
Tead inhibitors and uses thereof
|
|
US12091411B2
(en)
|
2022-01-31 |
2024-09-17 |
Kymera Therapeutics, Inc. |
IRAK degraders and uses thereof
|
|
EP4238564A1
(en)
*
|
2022-03-02 |
2023-09-06 |
Bash Biotech Inc |
New treatments of renal cell carcinoma
|
|
WO2023173057A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023173053A1
(en)
|
2022-03-10 |
2023-09-14 |
Ikena Oncology, Inc. |
Mek inhibitors and uses thereof
|
|
WO2023211889A1
(en)
|
2022-04-25 |
2023-11-02 |
Ikena Oncology, Inc. |
Polymorphic compounds and uses thereof
|
|
TW202404581A
(zh)
|
2022-05-25 |
2024-02-01 |
美商醫肯納腫瘤學公司 |
Mek抑制劑及其用途
|
|
KR20250056924A
(ko)
|
2022-08-02 |
2025-04-28 |
리미널 바이오사이언시스 리미티드 |
치환된 피리돈 gpr84 길항제 및 이의 용도
|
|
EP4565568A1
(en)
|
2022-08-02 |
2025-06-11 |
Liminal Biosciences Limited |
Heteroaryl carboxamide and related gpr84 antagonists and uses thereof
|
|
CN119894873A
(zh)
|
2022-08-02 |
2025-04-25 |
里米诺生物科学有限公司 |
芳基三唑基和相关gpr84拮抗剂及其用途
|
|
CN115745896B
(zh)
*
|
2022-11-18 |
2024-08-06 |
合肥医工医药股份有限公司 |
一种jak2激酶选择性抑制剂及其制备方法和用途
|
|
WO2024112894A1
(en)
|
2022-11-22 |
2024-05-30 |
PIC Therapeutics, Inc. |
Eif4e inhibitors and uses thereof
|
|
EP4673149A1
(en)
*
|
2023-03-02 |
2026-01-07 |
Trustlife Global Inc. |
New compounds and treatment of renal cell carcinoma
|
|
CN120379669A
(zh)
|
2023-06-23 |
2025-07-25 |
凯麦拉医疗公司 |
Irak降解剂及其用途
|
|
WO2025062372A1
(en)
|
2023-09-21 |
2025-03-27 |
Takeda Pharmaceutical Company Limited |
Tyk2 inhibitors for use in the treatment of inflammatory bowel disease
|