MX362412B - Inhibidores de biaril meta-pirimidina de cinasas. - Google Patents

Inhibidores de biaril meta-pirimidina de cinasas.

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Publication number
MX362412B
MX362412B MX2010010772A MX2010010772A MX362412B MX 362412 B MX362412 B MX 362412B MX 2010010772 A MX2010010772 A MX 2010010772A MX 2010010772 A MX2010010772 A MX 2010010772A MX 362412 B MX362412 B MX 362412B
Authority
MX
Mexico
Prior art keywords
kinases
meta
pyrimidine inhibitors
aryl meta
pyrimidine
Prior art date
Application number
MX2010010772A
Other languages
English (en)
Inventor
Richard M Soll
Joel Renick
John Hood
Jon Jianguo Cao
Dan Lohse
Chi Ching Mak
Pherson Andrew Mc
Glenn Noronha
Ved PATHAK
Binqi Zeng
Original Assignee
Targegen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Targegen Inc filed Critical Targegen Inc
Publication of MX362412B publication Critical patent/MX362412B/es

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    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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  • Vascular Medicine (AREA)

Abstract

La invención provee compuestos de biaril-meta-pirimidina que tiene la estructura general (A); (Ver fórmula A) los compuestos de pirimidina de la invención son capaces de inhibir cinasas, tales como miembros de la familia Jak de la cinasa, y algunas otras cinasas específicas de receptor y que no son de receptor.
MX2010010772A 2005-11-01 2006-10-26 Inhibidores de biaril meta-pirimidina de cinasas. MX362412B (es)

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