IL99552A0 - Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof - Google Patents

Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof

Info

Publication number
IL99552A0
IL99552A0 IL99552A IL9955291A IL99552A0 IL 99552 A0 IL99552 A0 IL 99552A0 IL 99552 A IL99552 A IL 99552A IL 9955291 A IL9955291 A IL 9955291A IL 99552 A0 IL99552 A0 IL 99552A0
Authority
IL
Israel
Prior art keywords
dna sequences
coexpression
kit
preparation
methods
Prior art date
Application number
IL99552A
Other languages
English (en)
Original Assignee
Ixsys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24361342&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL99552(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ixsys Inc filed Critical Ixsys Inc
Publication of IL99552A0 publication Critical patent/IL99552A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B40/00Libraries per se, e.g. arrays, mixtures
    • C40B40/02Libraries contained in or displayed by microorganisms, e.g. bacteria or animal cells; Libraries contained in or displayed by vectors, e.g. plasmids; Libraries containing only microorganisms or vectors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/44Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material not provided for elsewhere, e.g. haptens, metals, DNA, RNA, amino acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1034Isolating an individual clone by screening libraries
    • C12N15/1037Screening libraries presented on the surface of microorganisms, e.g. phage display, E. coli display
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/65Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/735Fusion polypeptide containing domain for protein-protein interaction containing a domain for self-assembly, e.g. a viral coat protein (includes phage display)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2795/00Bacteriophages
    • C12N2795/00011Details
    • C12N2795/14011Details ssDNA Bacteriophages
    • C12N2795/14022New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Steroid Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
IL99552A 1990-09-28 1991-09-24 Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof IL99552A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59021990A 1990-09-28 1990-09-28

Publications (1)

Publication Number Publication Date
IL99552A0 true IL99552A0 (en) 1992-08-18

Family

ID=24361342

Family Applications (1)

Application Number Title Priority Date Filing Date
IL99552A IL99552A0 (en) 1990-09-28 1991-09-24 Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof

Country Status (11)

Country Link
EP (1) EP0550645B1 (da)
JP (1) JP3373510B2 (da)
AT (1) ATE204607T1 (da)
AU (1) AU667291B2 (da)
CA (1) CA2092802A1 (da)
DE (1) DE69132700T2 (da)
IE (1) IE63054B1 (da)
IL (1) IL99552A0 (da)
NZ (1) NZ239988A (da)
TW (1) TW314553B (da)
WO (1) WO1992006204A1 (da)

Families Citing this family (842)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
US7413537B2 (en) 1989-09-01 2008-08-19 Dyax Corp. Directed evolution of disulfide-bonded micro-proteins
US5498538A (en) * 1990-02-15 1996-03-12 The University Of North Carolina At Chapel Hill Totally synthetic affinity reagents
US5747334A (en) * 1990-02-15 1998-05-05 The University Of North Carolina At Chapel Hill Random peptide library
US5427908A (en) * 1990-05-01 1995-06-27 Affymax Technologies N.V. Recombinant library screening methods
GB9015198D0 (en) * 1990-07-10 1990-08-29 Brien Caroline J O Binding substance
GB9206318D0 (en) * 1992-03-24 1992-05-06 Cambridge Antibody Tech Binding substances
US7063943B1 (en) 1990-07-10 2006-06-20 Cambridge Antibody Technology Methods for producing members of specific binding pairs
US6916605B1 (en) 1990-07-10 2005-07-12 Medical Research Council Methods for producing members of specific binding pairs
US6172197B1 (en) 1991-07-10 2001-01-09 Medical Research Council Methods for producing members of specific binding pairs
EP1820858B1 (en) 1991-03-01 2009-08-12 Dyax Corporation Chimeric protein comprising micro-protein having two or more disulfide bonds and embodiments thereof
ATE414768T1 (de) * 1991-04-10 2008-12-15 Scripps Research Inst Bibliotheken heterodimerer rezeptoren mittels phagemiden
US5962255A (en) * 1992-03-24 1999-10-05 Cambridge Antibody Technology Limited Methods for producing recombinant vectors
US6492160B1 (en) 1991-05-15 2002-12-10 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
DE69230142T2 (de) 1991-05-15 2000-03-09 Cambridge Antibody Technology Ltd. Verfahren zur herstellung von spezifischen bindungspaargliedern
US6225447B1 (en) 1991-05-15 2001-05-01 Cambridge Antibody Technology Ltd. Methods for producing members of specific binding pairs
US5858657A (en) * 1992-05-15 1999-01-12 Medical Research Council Methods for producing members of specific binding pairs
US5733731A (en) * 1991-10-16 1998-03-31 Affymax Technologies N.V. Peptide library and screening method
US5270170A (en) * 1991-10-16 1993-12-14 Affymax Technologies N.V. Peptide library and screening method
PT1024191E (pt) 1991-12-02 2008-12-22 Medical Res Council Produção de auto-anticorpos a partir de reportórios de segmentos de anticorpo e exibidos em fagos
US5733743A (en) * 1992-03-24 1998-03-31 Cambridge Antibody Technology Limited Methods for producing members of specific binding pairs
US5770356A (en) * 1992-09-04 1998-06-23 The Scripps Research Institute Phagemids coexpressing a surface receptor and a surface heterologous protein
WO1994011496A1 (en) * 1992-11-10 1994-05-26 Ixsys, Inc. Soluble peptides having constrained, secondary conformation in solution and method of making same
ZA938243B (en) * 1992-11-12 1995-05-04 Hybritech Inc Altered affinity polypeptides of metal chelate binding antibodies
US6955900B1 (en) 1993-02-02 2005-10-18 The Scripps Research Institute Methods for producing polypeptide binding sites, monoclonal antibodies and compositions thereof
IT1270939B (it) * 1993-05-11 1997-05-26 Angeletti P Ist Richerche Bio Procedimento per la preparazione di immunogeni e reagenti diagnostici,e immunogeni e reagenti diagnostici cosi' ottenibili.
US6010861A (en) * 1994-08-03 2000-01-04 Dgi Biotechnologies, Llc Target specific screens and their use for discovering small organic molecular pharmacophores
US7368111B2 (en) 1995-10-06 2008-05-06 Cambridge Antibody Technology Limited Human antibodies specific for TGFβ2
US6537776B1 (en) 1999-06-14 2003-03-25 Diversa Corporation Synthetic ligation reassembly in directed evolution
US6096548A (en) 1996-03-25 2000-08-01 Maxygen, Inc. Method for directing evolution of a virus
IL129222A0 (en) 1996-10-01 2000-02-17 Geron Corp Telomerase reverse transcriptase
EP2339002A1 (en) 1996-10-16 2011-06-29 ZymoGenetics, Inc. Fibroblast growth factor homologs
US6310191B1 (en) 1998-02-02 2001-10-30 Cosmix Molecular Biologicals Gmbh Generation of diversity in combinatorial libraries
DK0968283T3 (da) * 1997-01-31 2003-08-25 Cosmix Molecular Biolog Gmbh Dannelse af diversitet i kombinatoriske biblioteker
US6057098A (en) * 1997-04-04 2000-05-02 Biosite Diagnostics, Inc. Polyvalent display libraries
US6555310B1 (en) 1997-04-04 2003-04-29 Biosite Diagnostics, Inc. Polyclonal libraries
EP1030861A4 (en) 1997-10-31 2001-09-05 Maxygen Inc MODIFICATION OF VIRUSTROPISMIUS AND THE ECONOMIC SPECTRUM BY VIRAL GENOM MIXING
US7390619B1 (en) 1998-02-11 2008-06-24 Maxygen, Inc. Optimization of immunomodulatory properties of genetic vaccines
DE19816129A1 (de) * 1998-04-09 1999-10-14 Dolores Schendel T-Zellrezeptor-Expressionskassette
BRPI9911086B1 (pt) 1998-06-10 2016-08-02 Novozymes As composição de limpeza, processo para tratar tecidos a máquina, e uso de uma mananase
US6190908B1 (en) * 1998-08-12 2001-02-20 The Scripps Research Institute Modulation of polypeptide display on modified filamentous phage
DK1137773T3 (da) 1998-12-07 2008-12-08 Zymogenetics Inc Væsktfaktorhomolog ZVEGF3
SI1642972T1 (sl) 1999-01-07 2010-05-31 Zymogenetics Inc Terapevtske uporabe BR X topnih receptorjev
AU3391900A (en) 1999-03-05 2000-09-21 Maxygen, Inc. Encryption of traits using split gene sequences
KR100743640B1 (ko) 1999-03-09 2007-07-27 지모제넥틱스, 인코포레이티드 신규한 사이토킨 zalpha 11 리간드
US6492497B1 (en) 1999-04-30 2002-12-10 Cambridge Antibody Technology Limited Specific binding members for TGFbeta1
EP2241623A3 (en) 1999-07-07 2010-12-01 ZymoGenetics, Inc. Monoclonal antibody against a human cytokine receptor
US7135287B1 (en) 1999-10-02 2006-11-14 Biosite, Inc. Human antibodies
US6794132B2 (en) 1999-10-02 2004-09-21 Biosite, Inc. Human antibodies
US6680209B1 (en) 1999-12-06 2004-01-20 Biosite, Incorporated Human antibodies as diagnostic reagents
AU2292601A (en) 1999-12-23 2001-07-03 Zymogenetics Inc. Novel cytokine zcyto18
ES2279809T3 (es) 2000-04-05 2007-09-01 Zymogenetics, Inc. Receptores de citoquina zalfa11 solubles.
EP1278852B1 (en) 2000-05-11 2010-07-07 ZymoGenetics, Inc. Zsig33-like peptides
CA2412239C (en) 2000-06-26 2013-05-28 Zymogenetics, Inc. Cytokine receptor zcytor17
EP1399553A2 (en) 2000-12-12 2004-03-24 The University of Connecticut Polynucleotides encoding cellular transporters and methods of use therof
US7309783B2 (en) 2001-05-09 2007-12-18 The University Of Connecticut Mammalian early developmental regulator gene
ES2521615T3 (es) 2001-06-06 2014-11-13 Novozymes A/S Endo-beta-1,4-glucanasa
ES2334338T3 (es) 2001-11-05 2010-03-09 Zymogenetics, Inc. Antagonistas de il-21.
EP2840089A1 (en) 2002-01-18 2015-02-25 ZymoGenetics, Inc. Cytokine receptor zcytor17 multimers
DK1961811T3 (da) 2002-01-18 2010-11-08 Zymogenetics Inc Cytokinligand til behandling af asthma og luftvejs-hyper-responsivitet
US7094579B2 (en) 2002-02-13 2006-08-22 Xoma Technology Ltd. Eukaryotic signal sequences for prokaryotic expression
CN1659274A (zh) 2002-04-19 2005-08-24 津莫吉尼蒂克斯公司 细胞因子受体
DK1531850T3 (da) 2002-06-07 2012-06-04 Zymogenetics Inc Anvendelse af 1L-21 og monoklonalt antistof til behandling af solide cancere
AU2003274463B2 (en) 2002-06-10 2009-10-29 University Of Rochester Gene differentially expressed in breast and bladder cancer and encoded polypeptides
AU2003282724B2 (en) 2002-10-02 2010-03-04 Catalyst Biosciences, Inc. Methods of generating and screening for proteases with altered specificity
US7939304B2 (en) 2002-10-02 2011-05-10 Catalyst Biosciences, Inc. Mutant MT-SP1 proteases with altered substrate specificity or activity
EP1947116B1 (en) 2003-02-10 2017-06-21 2-BBB Medicines B.V. Differentially expressed nucleic acids in the blood-brain barrier under inflammatory conditions
ES2393058T3 (es) 2003-05-02 2012-12-18 Novozymes Inc. Variantes de beta-glucosidasa
US9708410B2 (en) 2003-05-30 2017-07-18 Janssen Biotech, Inc. Anti-tissue factor antibodies and compositions
WO2005014028A1 (en) 2003-08-08 2005-02-17 Novo Nordisk A/S Interleukin-20 for treating and diagnosing conditions associated with neovascularisation
WO2005030926A2 (en) 2003-08-25 2005-04-07 Novozymes Inc. Variants of glycoside hydrolases
EP2641611A3 (en) 2003-10-17 2013-12-18 Novo Nordisk A/S Combination therapy
DK1682656T3 (da) 2003-10-28 2013-11-18 Novozymes Inc Polypeptider med beta-glucosidaseaktivitet og polynukleotider, der koder for dem
ES2469840T3 (es) 2004-01-30 2014-06-20 Novozymes Inc. Polip�ptidos con actividad de mejora celulol�tica y polinucle�tidos que los codifican
WO2006078256A2 (en) 2004-02-12 2006-07-27 Novozymes, Inc. Polypeptides having xylanase activity and polynucleotides encoding same
JP5629423B2 (ja) 2004-04-12 2014-11-19 カタリスト バイオサイエンシーズ, インコーポレイテッド 野生型及び変異型mt−sp1による、vegf及びvegf受容体の切断
US9045748B2 (en) 2004-05-27 2015-06-02 Novozymes, Inc. Methods for transforming and expression screening of filamentous fungal cells with a DNA library
EP1769070A4 (en) 2004-06-29 2007-12-12 Novozymes Inc POLYPEPTIDES WITH ALPHA-GLUCOSIDASE ACTIVITY AND POLYNUCLEOTIDES THAT CODE
EP2298872A3 (en) 2004-09-30 2011-08-10 Novozymes A/S Polypeptides having lipase activity and polynucleotides encoding same
MX285771B (es) 2004-10-04 2011-04-07 Novozymes As Polipeptidos que tienen avtividad de fitasa y polinucleotidos queridos mama y papa: codifican los mismos.
AR050895A1 (es) 2004-10-04 2006-11-29 Novozymes As Polipeptidos que tienen actividad de fitasa y polinucleotidos que los codifican
WO2006053565A2 (en) 2004-11-19 2006-05-26 Novozymes A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
EP1831384B1 (en) 2004-12-22 2015-08-12 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
EP1856156A2 (en) 2005-02-08 2007-11-21 ZymoGenetics, Inc. Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation
EP1863836B1 (en) 2005-03-18 2012-07-11 Novozymes Adenium Biotech A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
CA2601400A1 (en) 2005-03-19 2006-09-28 Medical Research Council Improvements in or relating to treatment and prevention of viral infections
CN101253263B (zh) 2005-04-27 2014-07-02 诺维信股份有限公司 具有内切葡聚糖酶活性的多肽和编码该多肽的多核苷酸
EP1891107B1 (en) 2005-05-12 2011-07-06 ZymoGenetics, Inc. Compositions and methods for modulating immune responses
EP3263581B2 (en) 2005-05-17 2025-07-09 University of Connecticut Compositions and methods for immunomodulation in an organism
WO2007023163A1 (en) 2005-08-26 2007-03-01 Novozymes A/S Polypeptides having antimicrobial activity and polynucleotides encoding same
EP1941023B1 (en) 2005-09-30 2017-04-05 Novozymes Inc. Methods for enhancing the degradation or conversion of cellulosic material
ES2368608T3 (es) 2006-03-20 2011-11-18 Novozymes, Inc. Polipéptidos con actividad endoglucanasa y polinucleótidos codifcando los polipéptidos.
WO2007115201A2 (en) 2006-03-30 2007-10-11 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US8106013B2 (en) 2006-05-19 2012-01-31 Georgia Tech Research Corporation ABC transporter ligand GATX1
EP2035452B1 (en) 2006-06-22 2012-04-25 Novo Nordisk A/S Soluble heterodimeric receptors and uses thereof
EP2049138A4 (en) 2006-07-14 2011-11-09 Georgia Tech Res Inst CLC KANALLIGAND
US20100040595A1 (en) 2006-09-29 2010-02-18 Novozymes A/S Xylanses for animal feed
US20100064393A1 (en) 2006-11-29 2010-03-11 Novozymes, Inc. Bacillus liceniformis chromosome
US7820408B2 (en) 2006-11-29 2010-10-26 Novozymes, Inc. Methods of improving the introduction of DNA into bacterial cells
HUE041957T2 (hu) 2006-12-01 2019-06-28 Novartis Ag Anti-P-szelektin antitestek és eljárások azok alkalmazására gyulladásos betegségek kezelésére
PL2129781T3 (pl) 2007-03-26 2014-07-31 Novozymes As Fitaza z Hafnia
DE102007016139A1 (de) 2007-03-30 2008-10-02 Jenabios Gmbh Verfahren zur regioselektiven Oxygenierung von N-Heterozyklen
EP2193195B1 (en) 2007-09-18 2014-12-17 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
CN102099055A (zh) 2007-10-04 2011-06-15 津莫吉尼蒂克斯公司 B7家族成员zB7H6及相关的组合物和方法
WO2009065415A1 (en) 2007-11-21 2009-05-28 Roskilde Universitet Polypeptides comprising an ice-binding activity
DK2215224T3 (da) 2007-11-27 2014-01-27 Novozymes As Polypeptider med alfa-glucuronidaseaktivitet og polynukleotider, der koder for dem
US20100267067A1 (en) 2007-11-29 2010-10-21 Novozymes A/S Synthase Inhibitor Screening Method
WO2009073709A1 (en) 2007-12-06 2009-06-11 Novozymes A/S Polypeptides having acetylxylan esterase activity and polynucleotides encoding same
NZ598403A (en) 2007-12-19 2012-07-27 Novozymes As Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CA2710680C (en) 2007-12-26 2018-10-16 Vaccinex, Inc. Anti-c35 antibody combination therapies and methods
KR101720760B1 (ko) 2008-01-25 2017-03-28 오르후스 우니베르시테트 Igfbp-4에 대한 papp-a 활성의 선택적 엑소사이트 억제
MX2010011145A (es) 2008-04-11 2011-04-11 Merrimack Pharmaceuticals Inc Enlazadores de la albumina de suero humana y conjugados de la misma.
RU2545721C2 (ru) 2008-06-06 2015-04-10 Новозимс А/С Варианты семейства, состоящего из 44 ксилоглюканаз
PL3404088T3 (pl) 2008-06-06 2025-04-28 The Procter & Gamble Company Kompozycja detergentu zawierająca odmianę z grupy 44 ksyloglukanazy
CN102083451A (zh) 2008-06-12 2011-06-01 赛恩泰新公司 癌症的抑制
CA2727082C (en) 2008-06-12 2019-02-26 Syntaxin Limited Fusion proteins for use in suppression of acromegaly
EP2623112B1 (en) 2008-06-27 2015-03-04 Zymogenetics, Inc. Soluble hybrid Fc gamma receptors and related methods
SG172709A1 (en) 2008-07-18 2011-07-28 Novozymes Adenium Biotech As Treatment of inflammatory bowel diseases with mammal beta defensins
KR20160116056A (ko) 2008-08-14 2016-10-06 테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 항-il-12/il-23 항체
GB0820970D0 (en) 2008-11-17 2008-12-24 Syntaxin Ltd Suppression of cancer
EP2857515B1 (en) 2008-11-20 2018-02-21 Novozymes Inc. Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
US7771983B2 (en) 2008-12-04 2010-08-10 Novozymos, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US9493759B2 (en) 2008-12-12 2016-11-15 Novozymes, Inc. Polypeptides having aspartic endopeptidase activity and polynucleotides encoding same
US20110296557A1 (en) 2008-12-12 2011-12-01 Novozymes, Inc. Polypeptides Having Lipase Activity And Polynucleotides Encoding Same
US20110269206A1 (en) 2008-12-15 2011-11-03 Novozymes, Inc Polypeptides Having Catalase Activity And Polynucleotides Encoding Same
CA2746757A1 (en) 2008-12-16 2010-07-08 Novozymes, Inc. Polypeptides having alpha-mannosidase activity and polynucleotides encoding same
WO2010074955A1 (en) 2008-12-16 2010-07-01 Novozymes, Inc. Polypeptides having carboxypeptidase activity and polynucleotides encoding same
EP2379729A2 (en) 2008-12-19 2011-10-26 Novozymes A/S Use of enzymes having silicase activity
AU2010206181B2 (en) 2009-01-21 2015-01-15 Novozymes A/S Polypeptides having esterase activity and nucleic acids encoding the same
EP2391715A1 (en) 2009-01-28 2011-12-07 Novozymes Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
WO2010088463A2 (en) 2009-01-30 2010-08-05 Novozymes, Inc. Polypeptides having expansin activity and polynucleotides encoding same
WO2010087702A1 (en) 2009-01-30 2010-08-05 Stichting Katholieke Universiteit TET2 gene as a marker for diagnosing a myelodysuplastic syndrome (MDS) or an acute myeloid leukemia (AML) and determining the prognosis in a subject
WO2010088447A1 (en) 2009-01-30 2010-08-05 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
WO2010091221A1 (en) 2009-02-06 2010-08-12 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
WO2010089302A1 (en) 2009-02-06 2010-08-12 University Of Chile Protein and dna sequence encoding a cold adapted xylanase
KR101722961B1 (ko) 2009-02-11 2017-04-04 알부메딕스 에이/에스 알부민 변이체 및 접합체
CN102414317B (zh) 2009-02-27 2014-11-05 诺维信公司 具有减少的金属肽酶表达、适于重组多肽产生的突变细胞
WO2010106068A1 (en) 2009-03-17 2010-09-23 Novozymes A/S Polypeptides having tyrosinase activity and polynucleotides encoding same
WO2010108918A1 (en) 2009-03-24 2010-09-30 Novozymes A/S Polypeptides having acetyl xylan esterase activity and polynucleotides encoding same
EP2248893A1 (en) 2009-05-06 2010-11-10 Novozymes A/S DFPase Enzymes from Octopus Vulgaris
CA2763031A1 (en) 2009-05-29 2010-12-02 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
EP2438163B1 (en) 2009-06-02 2015-01-21 Novozymes Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
CN102712919B (zh) 2009-06-26 2017-06-23 诺维信北美公司 热稳定性碳酸酐酶及其用途
US8143021B2 (en) 2009-07-07 2012-03-27 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
MX2012001060A (es) 2009-07-24 2012-03-14 Novozymes As Carbohidrato-oxidasas.
WO2011014458A1 (en) 2009-07-28 2011-02-03 Novozymes, Inc. Polypeptides having phytase activity and polynucleotides encoding same
MX2012002095A (es) 2009-08-21 2012-04-10 Novozymes As Polipeptidos que tienen actividad de isoamilasa y polinucleotidos que codifican los mismos.
AU2010289725A1 (en) 2009-09-01 2012-04-05 Novozymes, Inc. Methods for improving malic acid production in filamentous fungi
WO2011034421A1 (en) 2009-09-16 2011-03-24 Stichting Het Nederlands Kanker Instituut Fra-1 target genes as drug targets for treating cancer
WO2011035027A2 (en) 2009-09-17 2011-03-24 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2011035029A1 (en) 2009-09-18 2011-03-24 Novozymes, Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
EP2305717A1 (en) 2009-09-21 2011-04-06 Koninklijke Nederlandse Akademie van Wetenschappen Inhibiting TNIK for treating colon cancer
CN102648273B (zh) 2009-09-25 2017-04-26 诺维信公司 枯草蛋白酶变体
US9598692B2 (en) 2009-09-25 2017-03-21 University Of Oslo Multivalent phage display systems and methods
CN102648277B (zh) 2009-09-25 2015-05-20 诺维信公司 蛋白酶变体的用途
DK2483295T3 (da) 2009-09-29 2016-02-22 Novozymes Inc Polypeptider med cellulolytisk forbedrende aktivitet og polynukleotider, der koder for dem
CA2775347A1 (en) 2009-09-29 2011-04-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
CN102695720B (zh) 2009-09-30 2018-02-16 诺维信股份有限公司 具有纤维素分解增强活性的多肽和编码该多肽的多核苷酸
US8586829B2 (en) 2009-09-30 2013-11-19 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
BR112012006873A2 (pt) 2009-10-23 2015-09-08 Novozymes Inc variante isolada, polinucleotideo isolado, metodo para produzir uma variante, planta transgenica, parte de planta ou celula d eplanta, e, metodos para degradar ou converter um materialcelulósico, para produzir um produto de fermentação, e, para fermentar um material celulósico.
US20120260371A1 (en) 2009-10-29 2012-10-11 Novozymes A/S Polypeptides Having Cellobiohydrolase Activity and Polynucleotides Encoding Same
EP2493921B1 (en) 2009-10-30 2018-09-26 Albumedix Ltd Albumin variants
US9267125B2 (en) 2009-11-06 2016-02-23 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2011057083A1 (en) 2009-11-06 2011-05-12 Novozymes, Inc. Polypeptides having xylanase activity and polynucleotides encoding same
EP2325311A1 (en) 2009-11-18 2011-05-25 Pierre Fabre Medicament Novel phage display vector
AU2010276468B2 (en) 2009-11-30 2015-05-14 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
ES2534066T3 (es) 2009-11-30 2015-04-17 Novozymes A/S Polipéptidos que tienen actividad de glucoamilasa y polinucleótidos que codifican los mismos
MX2012006176A (es) 2009-12-01 2012-06-25 Novozymes North America Inc Polipeptidos que tienen actividad de glucoamilasa y polinucleotidos que codifican los mismos.
TW201125577A (en) 2009-12-02 2011-08-01 Novozymes As Use of defensins for treatment of infective endocarditis
EP2507369A1 (en) 2009-12-03 2012-10-10 Novozymes A/S Variants of a polypeptide with lipolytic activity and improved stability
AU2010329917B2 (en) 2009-12-09 2014-12-04 Novozymes A/S Methods of producing GH8 xylanase variants
US8653024B2 (en) 2009-12-11 2014-02-18 Adenium Biotech Aps Use of AMPs for treatment of UTI/cystitis
EP2501792A2 (en) 2009-12-29 2012-09-26 Novozymes A/S Gh61 polypeptides having detergency enhancing effect
WO2011080353A1 (en) 2010-01-04 2011-07-07 Novozymes A/S Stabilization of alpha-amylases towards calcium depletion and acidic ph
EP2354244A1 (en) 2010-02-04 2011-08-10 Stichting Top Institute Food and Nutrition MBL2 as a marker of liver-specific insulin resistance
EP2354245A1 (en) 2010-02-04 2011-08-10 Stichting Top Institute Food and Nutrition MBL2 as a marker of hepatic PPAR- activity
WO2011104284A1 (en) 2010-02-25 2011-09-01 Novozymes A/S Polypeptides having antimicrobial activity
WO2011104339A1 (en) 2010-02-25 2011-09-01 Novozymes A/S Variants of a lysozyme and polynucleotides encoding same
WO2011109524A2 (en) 2010-03-03 2011-09-09 Novozymes, Inc. Xylanase variants and polynucleotides encoding same
US9222109B2 (en) 2010-03-28 2015-12-29 Novozymes A/S Enzymatic hydroxylation of aliphatic hydrocarbon
EP3070171B1 (en) 2010-03-30 2018-06-13 Novozymes A/S Process for enhancing by-products from fermentation processes
CN102918151B (zh) 2010-03-31 2015-09-09 诺维信股份有限公司 纤维二糖水解酶变体及编码其的多核苷酸
WO2011127802A1 (en) 2010-04-14 2011-10-20 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
BR112012027464A2 (pt) 2010-06-04 2019-09-24 Novozymes Inc célula hospedeira, método para produzir um ácido dicarboxílico c4, e, método para aumentar a produção de ácido dicarboxílico c4.
US8822642B2 (en) 2010-06-09 2014-09-02 Zymogenetics, Inc. Dimeric fusion proteins and related compositions and methods
US9499813B2 (en) 2010-06-10 2016-11-22 President And Fellows Of Harvard College Systems and methods for amplification and phage display
US8835604B2 (en) 2010-06-12 2014-09-16 Adenium Biotech Aos Antimicrobial peptide variants and polynucleotides encoding same
CN102947458B (zh) 2010-06-21 2016-05-04 诺维信股份有限公司 用于丝状真菌中c4-二羧酸的改善的产生的方法
WO2011163269A1 (en) 2010-06-21 2011-12-29 Novozymes, Inc. Aspergillus aculeatus derived polypeptides having c4-dicarboxylic acid transporter activity and polynucleotides encoding same
EP2588604B1 (en) 2010-06-30 2016-06-29 Novozymes, Inc. Polypeptides having beta-glucosidase activity and polynucleotides encoding same
BR112013002979A2 (pt) 2010-08-12 2016-06-07 Novozymes Inc composição, e, método para degradar ou converter um material celulósico, para produzir um produto de fermentação, e para fermentar um material celulósico.
AU2011292497B2 (en) 2010-08-17 2015-10-15 PRRIL Holding B.V. A novel method for diagnosing Q-fever using a cellular immunological test
CN103180438A (zh) 2010-08-24 2013-06-26 诺维信公司 热稳定性Persephonella碳酸酐酶及其用途
US8624082B2 (en) 2010-08-30 2014-01-07 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
US20130212746A1 (en) 2010-08-30 2013-08-15 Novoyzmes A/S Polypeptides Having Hemicellulolytic Activity And Polynucleotides Encoding Same
DK2735611T3 (da) 2010-08-30 2019-01-28 Novozymes As Polypeptider med cellulolyseforøgende aktivitet og polynukleotider, som koder for dem
WO2012030845A2 (en) 2010-08-30 2012-03-08 Novozymes A/S Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
US9267126B2 (en) 2010-08-30 2016-02-23 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US9187742B2 (en) 2010-08-30 2015-11-17 Novozymes, Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2012035103A1 (en) 2010-09-16 2012-03-22 Novozymes A/S Lysozymes
CA2811678C (en) 2010-09-21 2019-10-01 Stichting Katholieke Universiteit Novel method for diagnosing lyme disease using a cellular immunological test
US10246691B2 (en) 2010-09-30 2019-04-02 Novozymes, Inc. Variants of polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
US9816082B2 (en) 2010-09-30 2017-11-14 Novozymes, Inc. Variants of polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
ES2563209T3 (es) 2010-10-01 2016-03-11 Novozymes, Inc. Variantes de beta-glucosidasa y polinucleótidos que codifican las mismas
JP5944908B2 (ja) 2010-10-01 2016-07-05 ノボザイムス アクティーゼルスカブ エンドペプチダーゼ活性を有するポリペプチド及びそれをコードするポリヌクレオチド
GB201016742D0 (en) 2010-10-05 2010-11-17 Health Prot Agency Clostridium difficile antigens
BR112013009817B1 (pt) 2010-10-26 2020-02-04 Novozymes As métodos de degradar ou converter refugo de cana de açúcar, de produzir um produto de fermentação, e, de fermentar refugo de cana de açúcar
CN103282376A (zh) 2010-10-29 2013-09-04 诺维信公司 具有琥珀酰CoA:乙酰乙酸转移酶活性的多肽及其编码多核苷酸
EP2633030A1 (en) 2010-10-29 2013-09-04 Novozymes A/S Recombinant n-propanol and isopropanol production
WO2012061517A1 (en) 2010-11-02 2012-05-10 Novozymes, Inc. Methods of pretreating cellulosic material with a gh61 polypeptide
EP2635594B1 (en) 2010-11-04 2017-01-11 Novozymes Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
ES2605235T3 (es) 2010-11-08 2017-03-13 Novozymes A/S Polipéptidos que tienen actividad de glucoamilasa y polinucleótidos que codifican los mismos
ES2649555T3 (es) 2010-11-08 2018-01-12 Novozymes A/S Polipéptidos con actividad glucoamilasa y polinucleótidos que los codifican
BR112013009026A2 (pt) 2010-11-12 2016-07-12 Novozymes Inc polipeptídeo isolado, célula hospedeira recombinante, métodos para produzir um polipeptídeo, um mutante de uma célula precursora, uma proteína, e um produto de fermentação, para inibir a expressão de um polipeptídeo, para degradar ou converter um material celulósico, e método para fermentar um material celulósico, planta transgênica, parte de planta ou célula de planta, molécula de rna inibidora de filamento duplo, polinucleotídeo isolado, e, formulação de caldo integral ou composição de cultura de célula
MX356647B (es) 2010-11-12 2018-06-07 Novozymes As Polipeptidos que tienen actividad de fosfolipasa c y polinucleotidos que codifican los mismos.
WO2012068509A1 (en) 2010-11-18 2012-05-24 Novozymes, Inc. Chimeric polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2649188A1 (en) 2010-12-06 2013-10-16 Novozymes North America, Inc. Methods of hydrolyzing oligomers in hemicellulosic liquor
EP2465928A1 (en) 2010-12-16 2012-06-20 Academisch Medisch Centrum bij de Universiteit van Amsterdam Treatment of Th17-mediated diseases
MX2013007720A (es) 2011-01-26 2013-08-09 Novozymes As Polipeptidos que tienen actividad celobiohidrolasa y polinucleotidos que codifican para los mismos.
EP2668270B1 (en) 2011-01-26 2018-11-21 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
EP2668269B1 (en) 2011-01-26 2018-01-03 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
US8759023B2 (en) 2011-01-26 2014-06-24 Novozymes Inc. Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
WO2012103322A1 (en) 2011-01-26 2012-08-02 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
US9434972B2 (en) 2011-01-31 2016-09-06 Novozymes North America, Inc. Processes for enzymatic refining of pretreated cellulosic material for saccharification
EP2675883A2 (en) 2011-02-16 2013-12-25 Novozymes A/S Detergent compositions comprising metalloproteases
JP2014511409A (ja) 2011-02-16 2014-05-15 ノボザイムス アクティーゼルスカブ 金属プロテアーゼを含む洗剤組成物
MX2013009177A (es) 2011-02-16 2013-08-29 Novozymes As Composiciones detergentes que comprenden metaloproteasas de m7 o m35.
CN103384678B (zh) 2011-02-23 2017-01-18 诺维信股份有限公司 具有纤维素水解增强活性的多肽及其编码多核苷酸
WO2012118848A1 (en) 2011-02-28 2012-09-07 Novozymes, Inc. Microorganism for c4-dicarboxylic acid production
CN103608461B (zh) 2011-03-09 2016-08-03 诺维信公司 增加多肽的纤维素分解增强活性的方法
WO2012122477A1 (en) 2011-03-10 2012-09-13 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
CN103443278B (zh) 2011-03-23 2017-07-04 诺维信公司 生产分泌型多肽的方法
WO2012127002A1 (en) 2011-03-23 2012-09-27 Novozymes A/S Sweet-tasting polypeptide from gram-positive bacteria
US9879294B2 (en) 2011-03-25 2018-01-30 Novozymes A/S Methods for degrading or converting cellulosic material
US20140080182A1 (en) 2011-03-31 2014-03-20 Novozymes, Inc. Cellulose Binding Domain Variants and Polynucleotides Encoding Same
WO2012135659A2 (en) 2011-03-31 2012-10-04 Novozymes A/S Methods for enhancing the degradation or conversion of cellulosic material
EP2702153B1 (en) 2011-04-28 2018-12-12 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
DK2702162T3 (da) 2011-04-29 2020-05-18 Novozymes Inc Fremgangsmåder til forbedring af nedbrydningen eller omdannelsen af celluloseholdigt materiale
CA2830660A1 (en) 2011-05-05 2012-11-08 Novozymes Biopharma Dk A/S Albumin variants
GB201108108D0 (en) 2011-05-16 2011-06-29 Syntaxin Ltd Therapeutic fusion proteins
WO2012159007A1 (en) 2011-05-19 2012-11-22 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
US8993286B2 (en) 2011-05-19 2015-03-31 Novozymes, Inc. Methods for enhancing the degradation of cellulosic material with chitin binding proteins
EP2527432A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Bi-directional cytosine deaminase-encoding selection marker
EP2527448A1 (en) 2011-05-23 2012-11-28 Novozymes A/S Simultaneous site-specific integrations of multiple gene-copies in filamentous fungi
MX349517B (es) 2011-06-24 2017-08-02 Novozymes As Polipeptidos que tienen actividad de proteasa y polinucleotidos que codifican los mismos.
BR122020009747B1 (pt) 2011-06-30 2021-07-20 Novozymes A/S Polipeptídeo e alfa-amilase variantes, composição detergente, e, utilização de uma alfa- amilase variante
EP2540824A1 (en) 2011-06-30 2013-01-02 The Procter & Gamble Company Cleaning compositions comprising amylase variants reference to a sequence listing
US9434932B2 (en) 2011-06-30 2016-09-06 Novozymes A/S Alpha-amylase variants
CA2840962C (en) 2011-07-06 2021-04-13 Novozymes A/S Alpha amylase variants and polynucleotides encoding same
WO2013004639A2 (en) 2011-07-07 2013-01-10 Novozymes A/S Enzymatic preparation of diols
JP6219277B2 (ja) 2011-07-08 2017-10-25 ディフェンシン セラピューティクス アンパルトセルスカブDefensin Therapeutics Aps 炎症性腸疾患の経口治療
CN103827298A (zh) 2011-07-15 2014-05-28 诺维信公司 脂肪酶变体及其编码多核苷酸
EP2734633B1 (en) 2011-07-22 2019-05-01 Novozymes North America, Inc. Processes for pretreating cellulosic material and improving hydrolysis thereof
EP3091073B2 (en) 2011-08-04 2023-03-08 Novozymes Inc. Polypeptides having xylanase activity and polynucleotides encoding same
CA2838758A1 (en) 2011-08-04 2013-02-07 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2013021064A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021061A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021059A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021060A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013021062A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
CN103732740B (zh) 2011-08-10 2018-07-31 诺维信公司 具有过氧化酶活性的多肽及编码该多肽的多核苷酸
WO2013021065A1 (en) 2011-08-10 2013-02-14 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
JP2014531895A (ja) 2011-08-15 2014-12-04 ノボザイムス アクティーゼルスカブ セルラーゼ活性を有するポリペプチドおよびそれをコードするポリヌクレオチド
US20130052213A1 (en) 2011-08-19 2013-02-28 Novozymes A/S Novel immunomodulatory peptide
WO2013026796A1 (en) 2011-08-19 2013-02-28 Novozymes A/S Polypeptides having protease activity
BR112014003444A2 (pt) 2011-08-19 2017-03-14 Novozymes Inc célula hospedeira recombinante, e, método para produzir um ácido c4-dicarboxílico
EP2748188A4 (en) 2011-08-26 2015-03-18 Novozymes As POLYPEPTIDES WITH GLUCCOAMYLASE ACTIVITY AND THESE CODING POLYNUCLEOTIDES
GB201115214D0 (en) 2011-09-02 2011-10-19 Health Prot Agency Influenza virus antibody compositions
CN103930543B (zh) 2011-09-06 2020-11-27 诺维信公司 葡糖淀粉酶变体和编码它们的多核苷酸
CA2847236A1 (en) 2011-09-09 2013-03-14 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
EP2753749B1 (en) 2011-09-09 2019-03-27 Novozymes A/S Improving properties of paper materials
CN103930555A (zh) 2011-09-13 2014-07-16 诺维信北美公司 水解和发酵纤维素材料的方法
US20140308705A1 (en) 2011-09-20 2014-10-16 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
US20140227738A1 (en) 2011-09-22 2014-08-14 Novozymes A/S Polypeptides Having Protease Activity and Polynucleotides Encoding Same
BR112014006807B1 (pt) 2011-09-23 2021-11-09 Novozymes A/S Método para modificação de cor de têxtil
CA2850070A1 (en) 2011-09-30 2013-04-04 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
CA2849303C (en) 2011-09-30 2019-09-17 Novozymes, Inc. Dehydrogenase variants and polynucleotides encoding same
CA2853000C (en) 2011-10-11 2022-03-15 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
CN103857794B (zh) 2011-10-17 2018-03-20 诺维信公司 α‑淀粉酶变体以及编码它们的多核苷酸
EP3495479B1 (en) 2011-10-17 2025-08-06 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2013064075A1 (en) 2011-10-31 2013-05-10 Novozymes, Inc. Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2013064195A1 (en) 2011-11-04 2013-05-10 Enel Ingegneria E Ricerca S.P.A. A new heat-stable carbonic anhydrase and uses thereof
WO2013068309A1 (en) 2011-11-08 2013-05-16 Novozymes A/S Methods for production of archeae protease in yeast
EP2780364A2 (en) 2011-11-18 2014-09-24 Eleven Biotherapeutics, Inc. Proteins with improved half-life and other properties
EP2780449B1 (en) 2011-11-18 2018-04-11 Novozymes, Inc. Polypeptides having beta-glucosidase activity, beta-xylosidase activity, or beta-glucosidase and beta-xylosidase activity and polynucleotides encoding same
US10351834B2 (en) 2011-11-21 2019-07-16 Novozymes, Inc. GH61 polypeptide variants and polynucleotides encoding same
WO2013075644A1 (en) 2011-11-22 2013-05-30 Novozymes, Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
CN103957929B (zh) 2011-11-25 2017-06-30 诺维信公司 具有溶菌酶活性的多肽和编码所述多肽的多核苷酸
WO2013076269A1 (en) 2011-11-25 2013-05-30 Novozymes A/S Subtilase variants and polynucleotides encoding same
US9624481B2 (en) 2011-12-01 2017-04-18 Novozymes, Inc. Polypeptides having beta-xylosidase activity and polynucleotides encoding same
WO2013079533A1 (en) 2011-12-02 2013-06-06 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
WO2013079531A2 (en) 2011-12-02 2013-06-06 Novozymes A/S Polypeptides having peroxygenase activity and polynucleotides encoding same
EP3272862A1 (en) 2011-12-16 2018-01-24 Novozymes, Inc. Polypeptides having laccase activity and polynucleotides encoding same
BR112014014697A2 (pt) 2011-12-19 2020-10-27 Novozymes, Inc. polipeptídeo isolado, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, métodos para produzir um polipeptídeo e uma proteína, para gerar oxigênio molecular, e para remover peróxido de hidrogênio do tecido, processos para degradar ou converter um material celulósico, e para produzir um produto de fermentação, e, formulação de caldo integral ou composição de cultura de células
JP2015504660A (ja) 2011-12-20 2015-02-16 ノボザイムス アクティーゼルスカブ サブチラーゼ変異体およびそれをコードするポリヌクレオチド
EP2607468A1 (en) 2011-12-20 2013-06-26 Henkel AG & Co. KGaA Detergent compositions comprising subtilase variants
CA2878019A1 (en) 2011-12-20 2013-06-27 Novozymes, Inc. Cellobiohydrolase variants and polynucleotides encoding same
AU2012360992B2 (en) 2011-12-28 2018-08-09 Novozymes A/S Polypeptides having protease activity
CN104350149A (zh) 2012-01-26 2015-02-11 诺维信公司 具有蛋白酶活性的多肽在动物饲料和洗涤剂中的用途
BR112014019142A2 (pt) 2012-02-03 2017-06-27 Procter & Gamble composições e métodos para tratamento de superfícies com lipases
CN104080908B (zh) 2012-02-03 2018-02-06 诺维信公司 脂肪酶变体以及编码它们的多核苷酸
EP2628785B1 (en) 2012-02-17 2016-05-18 Henkel AG & Co. KGaA Detergent compositions comprising subtilase variants
WO2013120948A1 (en) 2012-02-17 2013-08-22 Novozymes A/S Subtilisin variants and polynucleotides encoding same
EP2817325B1 (en) 2012-02-20 2019-06-26 Novozymes A/S Polypeptides having endoglucanase activity and polynucleotides encoding same
DK2825556T3 (da) 2012-03-16 2018-04-16 Albumedix As Albuminvarianter
WO2013144105A1 (en) 2012-03-31 2013-10-03 Novozymes A/S Epoxidation using peroxygenase
CN107988181A (zh) 2012-04-02 2018-05-04 诺维信公司 脂肪酶变体以及编码其的多核苷酸
US9394556B2 (en) 2012-04-23 2016-07-19 Novozymes A/S Polypeptides having glucuronyl esterase activity and polynucleotides encoding same
CN104245929A (zh) 2012-04-23 2014-12-24 诺维信公司 具有α-葡糖醛酸糖苷酶活性的多肽以及编码其的多核苷酸
WO2013160370A1 (en) 2012-04-25 2013-10-31 Novozymes A/S Method of baking
US10227579B2 (en) 2012-04-27 2019-03-12 Novozymes A/S GH61 polypeptide variants and polynucleotides encoding same
AR090971A1 (es) 2012-05-07 2014-12-17 Novozymes As Polipeptidos que tienen actividad de degradacion de xantano y polinucleotidos que los codifican
WO2013173711A1 (en) 2012-05-18 2013-11-21 Novozymes A/S Bacterial mutants with improved transformation efficiency
WO2013178699A1 (en) 2012-05-31 2013-12-05 Novozymes A/S Isopropanol production by bacterial hosts
US9512413B2 (en) 2012-05-31 2016-12-06 Novozymes A/S Polypeptides having organophosphorous hydrolase activity
EP2861749A1 (en) 2012-06-19 2015-04-22 Novozymes Bioag A/S Enzymatic reduction of hydroperoxides
BR112014031882A2 (pt) 2012-06-20 2017-08-01 Novozymes As uso de um polipeptídeo isolado, polipeptídeo, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira de expressão recombinante, métodos para produção de um polipeptídeo, para melhoria do valor nutricional de uma ração animal, e para o tratamento de proteínas, uso de pelo menos um polipeptídeo, aditivo de ração animal, ração animal, e, composição detergente
CN104471048B (zh) 2012-07-12 2018-11-16 诺维信公司 具有脂肪酶活性的多肽及编码它的多核苷酸
EP2875179B1 (en) 2012-07-18 2018-02-21 Novozymes A/S Method of treating polyester textile
CN104781412A (zh) 2012-07-20 2015-07-15 诺维信公司 5-羟甲基糠醛及其衍生物的酶氧化
PT3553172T (pt) 2012-08-16 2023-01-27 Novozymes As Método para tratamento de tecido com endoglucanase
MX2015001969A (es) 2012-08-17 2015-05-15 Novozymes As Variantes de asparaginasa termoestables y polinucleotidos que las codifican.
MX357022B (es) 2012-08-22 2018-06-25 Novozymes As Metaloproteasas de alicyclobacillus sp.
US20160145540A1 (en) 2012-08-22 2016-05-26 Novozymes A/S Detergent Compositions Comprising Metalloproteases
US20150203793A1 (en) 2012-08-22 2015-07-23 Novozymes A/S Metalloprotease from Exiguobacterium
AU2013311668B2 (en) 2012-09-05 2019-02-28 Novozymes A/S Polypeptides having protease activity
WO2014092832A2 (en) 2012-09-19 2014-06-19 Novozymes, Inc. Methods for enhancing the degradation or conversion of cellulosic material
CN104619721A (zh) 2012-09-27 2015-05-13 诺维信股份有限公司 具有改进的转化效率的细菌突变体
EP2904099B1 (en) 2012-10-05 2018-12-19 Novozymes A/S Preventing adhesion of bacteria
EP3586610B1 (en) 2012-10-08 2024-09-25 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
EP2906688B1 (en) 2012-10-12 2018-08-29 Novozymes A/S Polypeptides having peroxygenase activity
CN104704116B (zh) 2012-10-12 2018-09-28 诺维信公司 具有过氧合酶活性的多肽
US9534208B2 (en) 2012-10-12 2017-01-03 Novozymes A/S Polypeptides having peroxygenase activity
CN104718288B (zh) 2012-10-12 2018-11-16 诺维信公司 具有过氧合酶活性的多肽
US9453207B2 (en) 2012-10-12 2016-09-27 Novozymes A/S Polypeptides having peroxygenase activity
US9458435B2 (en) 2012-10-12 2016-10-04 Novozymes A/S Polypeptides having peroxygenase activity
WO2014056927A2 (en) 2012-10-12 2014-04-17 Novozymes A/S Polypeptides having peroxygenase activity
WO2014066141A2 (en) 2012-10-24 2014-05-01 Novozymes A/S Polypeptides having cellulolytic enhancing activity and polynucleotides encoding same
WO2014068010A1 (en) 2012-10-31 2014-05-08 Novozymes A/S Isopropanol production by bacterial hosts
MX2015005363A (es) 2012-11-08 2015-11-06 Novozymes Biopharma Dk As Variantes de albumina.
WO2014076232A2 (en) 2012-11-19 2014-05-22 Novozymes A/S Isopropanol production by recombinant hosts using an hmg-coa intermediate
CN105209626B (zh) 2012-11-30 2019-09-03 诺维信股份有限公司 通过重组酵母生产3-羟基丙酸
TR201910918T4 (tr) 2012-12-07 2019-08-21 Novozymes As Bakterilerin yapışmasının önlenmesi.
EP2740840A1 (en) 2012-12-07 2014-06-11 Novozymes A/S Improving drainage of paper pulp
CN104837993A (zh) 2012-12-07 2015-08-12 诺维信公司 用于在丝状真菌中产生位点特异性突变的方法
CN112852777A (zh) 2012-12-11 2021-05-28 诺维信公司 具有磷脂酶c活性的多肽以及对其进行编码的多核苷酸
BR112015013421A2 (pt) 2012-12-14 2017-11-14 Novozymes As E Novozymes Inc célula hospedeira microbiana transgênica, polipeptídeo isolado, métodos de produção de um polipeptídeo e de uma proteína, processos de degradação de um material celulósico, de produção de um produto de fermentação e de fermentação de um material celulósico, construção de ácido nucleico ou vetor de expressão, polipeptídeo isolado, e polinucleotídeo isolado
WO2014090940A1 (en) 2012-12-14 2014-06-19 Novozymes A/S Removal of skin-derived body soils
DK2935574T3 (da) 2012-12-17 2020-02-03 Novozymes As Alfaamylaser og polynukleotider, som koder for dem
US20150337280A1 (en) 2012-12-19 2015-11-26 Novozymes A/S Polypeptides Having Cellulolytic Enhancing Activity And Polynucleotides Encoding Same
EP2934177B1 (en) 2012-12-21 2017-10-25 Novozymes A/S Polypeptides having protease activiy and polynucleotides encoding same
BR112015014624A2 (pt) 2012-12-24 2017-10-10 Novozymes As polipeptídeo isolado, composição, polinucleotídeo isolado, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, e, método para tratamento de têxtil
EP2941485B1 (en) 2013-01-03 2018-02-21 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2014122109A1 (en) 2013-02-05 2014-08-14 Novozymes A/S Enzymatic preparation of indigo dyes and intermediates
US9441215B2 (en) 2013-02-06 2016-09-13 Novozymes A/S Polypeptides having protease activity
CN105164254B (zh) 2013-03-08 2019-06-28 诺维信公司 纤维二糖水解酶变体和编码它们的多核苷酸
WO2014142646A1 (en) 2013-03-13 2014-09-18 Stichting Katholieke Universiteit Q-fever diagnostic
WO2014147127A1 (en) 2013-03-21 2014-09-25 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
CN105073985B (zh) 2013-03-21 2025-05-23 诺维信公司 具有磷脂酶a活性的多肽与对其进行编码的多核苷酸
TR201819061T4 (tr) 2013-04-18 2019-01-21 Novozymes As Proteaz Aktivitesine Sahip Polipeptitler Ve Bunları Kodlayan Polinükleotitler
WO2014173980A2 (en) 2013-04-23 2014-10-30 Novozymes A/S Liquid automatic dish washing detergent compositions
US9963690B2 (en) 2013-04-30 2018-05-08 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
ES2674701T3 (es) 2013-04-30 2018-07-03 Novozymes A/S Variantes de glucoamilasa y polinucleótidos que las codifican
CN105308460A (zh) 2013-05-02 2016-02-03 天主教大学基金会 个性化药物
WO2014177709A1 (en) 2013-05-03 2014-11-06 Novozymes A/S Microencapsulation of detergent enzymes
DK2994529T3 (da) 2013-05-10 2019-03-04 Novozymes As Polypeptider med xylanaseaktivitet og polynukleotider, som koder for dem
EP4717756A2 (en) 2013-05-14 2026-04-01 Novozymes A/S Lipase variants and detergent compositions
CN105209613A (zh) 2013-05-17 2015-12-30 诺维信公司 具有α淀粉酶活性的多肽
EP3004315A2 (en) 2013-06-06 2016-04-13 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2014202089A2 (en) 2013-06-18 2014-12-24 Roskilde Universitet Variants of anti-freeze polypeptides
JP2016521579A (ja) 2013-06-21 2016-07-25 ノボザイムス アクティーゼルスカブ バチルス属(Bacillus)における分泌シグナルを含まないポリペプチドの生成
US20160145596A1 (en) 2013-06-27 2016-05-26 Novozymes A/S Subtilase Variants and Polynucleotides Encoding Same
US10378001B2 (en) 2013-06-27 2019-08-13 Novozymes A/S Subtilase variants and compositions comprising same
RU2015156280A (ru) 2013-07-04 2017-08-09 Новозимс А/С Полипептиды, обладающие эффектом против переосаждения, и полинуклеотиды, кодирующие их
WO2015004102A1 (en) 2013-07-09 2015-01-15 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
EP3022300B1 (en) 2013-07-17 2018-07-11 Novozymes A/S Pullulanase chimeras and polynucleotides encoding same
CN105358686A (zh) 2013-07-29 2016-02-24 诺维信公司 蛋白酶变体以及对其进行编码的多核苷酸
EP2832853A1 (en) 2013-07-29 2015-02-04 Henkel AG&Co. KGAA Detergent composition comprising protease variants
WO2015014803A1 (en) 2013-07-29 2015-02-05 Novozymes A/S Protease variants and polynucleotides encoding same
US9845484B2 (en) 2013-07-31 2017-12-19 Novozymes A/S 3-hydroxypropionic acid production by recombinant yeasts expressing an insect aspartate 1-decarboxylase
WO2015022429A1 (en) 2013-08-15 2015-02-19 Novozymes A/S Polypeptides having beta-1,3-galactanase activity and polynucleotides encoding same
WO2015049370A1 (en) 2013-10-03 2015-04-09 Novozymes A/S Detergent composition and use of detergent composition
WO2015059133A1 (en) 2013-10-22 2015-04-30 Novozymes A/S Cellobiose dehydrogenase variants and polynucleotides encoding same
EP2876156A1 (en) 2013-11-26 2015-05-27 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzymes and method for preparing hydroxylated L-lysine or L-ornithine and analogs thereof
WO2015079064A2 (en) 2013-11-29 2015-06-04 Novozymes A/S Peroxygenase variants
PT3080254T (pt) 2013-12-11 2024-07-30 Novozymes As Variantes cutinase e polinucleótidos que codificam o mesmo
EP2886656A1 (en) 2013-12-18 2015-06-24 Commissariat A L'energie Atomique Et Aux Energies Alternatives New enzyme and method for preparing 4-hydroxyl benzyl alcohol and derivatives thereof
EP3453757B1 (en) 2013-12-20 2020-06-17 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
US10208297B2 (en) 2014-01-22 2019-02-19 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same for cleaning
EP3097192B1 (en) 2014-01-22 2018-07-25 Novozymes A/S Pullulanase variants and polynucleotides encoding same
EP3521434A1 (en) 2014-03-12 2019-08-07 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
WO2015143144A1 (en) 2014-03-19 2015-09-24 Novozymes A/S Method for enhancing activity of an x143 polypeptide
EP4696776A3 (en) 2014-03-19 2026-04-22 Novozymes A/S Polypeptides having phospholipase c activity and polynucleotides encoding same
US20170015950A1 (en) 2014-04-01 2017-01-19 Novozymes A/S Polypeptides having alpha amylase activity
EP3129478B1 (en) 2014-04-10 2019-03-27 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
MX376770B (es) 2014-04-11 2025-03-07 Novozymes As Composición detergente.
WO2015158237A1 (en) 2014-04-15 2015-10-22 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
AU2015248807B2 (en) 2014-04-17 2021-07-22 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell for expressing proteins of interest
CN106661541B (zh) 2014-04-17 2021-09-03 贝林格尔·英格海姆Rcv两合公司 被工程化为过表达辅助蛋白的重组宿主细胞
WO2017186943A1 (en) 2016-04-29 2017-11-02 Novozymes A/S Detergent compositions and uses thereof
CN106459934A (zh) 2014-05-15 2017-02-22 诺维信公司 包括具有磷脂酶c活性的多肽的组合物及其应用
AR100606A1 (es) 2014-05-27 2016-10-19 Novozymes As Variantes de lipasas y polinucleótidos que las codifican
CA2950273C (en) 2014-05-30 2022-06-21 Novozymes A/S Variants of gh family 11 xylanase and polynucleotides encoding same
EP2952584A1 (en) 2014-06-04 2015-12-09 Boehringer Ingelheim RCV GmbH & Co KG Improved protein production
WO2015189371A1 (en) 2014-06-12 2015-12-17 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2015200659A1 (en) 2014-06-25 2015-12-30 Novozymes A/S Xylanase variants and polynucleotides encoding same
CN106471110A (zh) 2014-07-03 2017-03-01 诺维信公司 改进的非蛋白酶类酶稳定化
EP3739029A1 (en) 2014-07-04 2020-11-18 Novozymes A/S Subtilase variants and polynucleotides encoding same
US10550381B2 (en) 2014-07-04 2020-02-04 Novozymes A/S Variant proteases and amylases having enhanced storage stability
EP3183339A1 (en) 2014-08-20 2017-06-28 Novozymes A/S Xyloglucan endotransglycosylase variants and polynucleotides encoding same
EP3594335B1 (en) 2014-09-05 2024-05-01 Novozymes A/S Carbohydrate binding module variants and polynucleotides encoding same
WO2016062875A2 (en) 2014-10-23 2016-04-28 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
BR112017009320A2 (pt) 2014-11-04 2017-12-19 Novozymes As ração animal ou aditivo de ração animal, uso de ração animal ou aditivo de ração animal, e, métodos para preparação de uma ração animal, para melhoria do valor nutricional de uma ração animal, para tratamento de proteínas aumento da digestibilidade e/ou solubilidade da proteína, para melhoria de um ou mais parâmetros de desempenho em um animal e para produção de um polipeptídeo.
WO2016073610A1 (en) 2014-11-07 2016-05-12 Novozymes A/S Xylanase based bleach boosting
WO2016079305A1 (en) 2014-11-20 2016-05-26 Novozymes A/S Alicyclobacillus variants and polynucleotides encoding same
WO2016087327A1 (en) 2014-12-01 2016-06-09 Novozymes A/S Polypeptides having pullulanase activity comprising the x25, x45 and cbm41 domains
WO2016090059A1 (en) 2014-12-02 2016-06-09 Novozymes A/S Laccase variants and polynucleotides encoding same
CA2963331C (en) 2014-12-04 2024-09-10 Novozymes A/S VARIANTS OF SUBTILASE AND THE POLYNUCLEOTIDES CODING FOR THESE
US10260024B2 (en) 2014-12-04 2019-04-16 Novozymes A/S Liquid cleaning compositions comprising protease variants
WO2016087401A1 (en) 2014-12-05 2016-06-09 Novozymes A/S Lipase variants and polynucleotides encoding same
CN107002049A (zh) 2014-12-16 2017-08-01 诺维信公司 具有n‑乙酰基葡萄糖胺氧化酶活性的多肽
WO2016100910A1 (en) 2014-12-19 2016-06-23 Novozymes A/S Recombinant host cells for the production of 3-hydroxypropionic acid
MX383142B (es) 2014-12-19 2025-03-13 Novozymes As Composiciones que comprenden polipéptidos que tienen actividad xilanasa y polipéptidos que tienen actividad arabinofuranosidasa.
US11518987B2 (en) 2014-12-19 2022-12-06 Novozymes A/S Protease variants and polynucleotides encoding same
US10400230B2 (en) 2014-12-19 2019-09-03 Novozymes A/S Protease variants and polynucleotides encoding same
US10557127B2 (en) 2015-02-24 2020-02-11 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
US10294466B2 (en) 2015-02-25 2019-05-21 Danisco Us Inc. Alpha-glucosidase, compositions and methods
CN107406821B (zh) 2015-02-27 2021-10-15 诺维信公司 用于生产3-羟基丙酸的突变宿主细胞
BR112017020007B1 (pt) 2015-03-19 2022-09-20 Novozymes A/S Método para preparar um mosto com um nível aumentado de nitrogênio livre aminado (fan) e uso de uma protease
US20180112156A1 (en) 2015-04-10 2018-04-26 Novozymes A/S Laundry method, use of polypeptide and detergent composition
CN107636134A (zh) 2015-04-10 2018-01-26 诺维信公司 洗涤剂组合物
EP3283512A4 (en) 2015-04-17 2018-10-03 Distributed Bio Inc Method for mass humanization of non-human antibodies
US11685773B2 (en) 2015-04-30 2023-06-27 Abcheck S.R.O. Method for mass humanization of rabbit antibodies
AU2016259703B2 (en) 2015-05-08 2021-12-23 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
WO2016180749A1 (en) 2015-05-08 2016-11-17 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
EP3294883A1 (en) 2015-05-08 2018-03-21 Novozymes A/S Alpha-amylase variants having improved performance and stability
BR112017021489A2 (pt) 2015-05-27 2018-07-03 Novozymes A/S polipeptídeo tendo atividade de celobio-hidrolase, composição, formulação de caldo inteiro ou composição de cultura de células, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, célula hospedeira recombinante, métodos de produção do polipeptídeo.
WO2016196202A1 (en) 2015-05-29 2016-12-08 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
US10450539B2 (en) 2015-06-04 2019-10-22 Novozymes A/S Use of M4 metalloprotease in wort production
US10858637B2 (en) 2015-06-16 2020-12-08 Novozymes A/S Polypeptides with lipase activity and polynucleotides encoding same
CA2981342A1 (en) 2015-06-18 2016-12-22 Novozymes A/S Polypeptides having trehalase activity and the use thereof in process of producing fermentation products
EP4071244A1 (en) 2015-06-18 2022-10-12 Novozymes A/S Subtilase variants and polynucleotides encoding same
BR112017028063B1 (pt) 2015-06-26 2022-05-17 Novozymes A/S Método para produção de um extrato de café
WO2016207373A1 (en) 2015-06-26 2016-12-29 Novozymes A/S Polypeptides having peroxygenase activity
US10392742B2 (en) 2015-06-26 2019-08-27 Novozymes A/S Biofinishing system
MX394221B (es) 2015-07-01 2025-03-24 Novozymes As Metodos de reduccion de olor.
MX387681B (es) 2015-07-02 2025-03-18 Novozymes As Composiciones de pienso para animales y uso de las mismas.
EP3950939A3 (en) 2015-07-06 2022-06-08 Novozymes A/S Lipase variants and polynucleotides encoding same
US10577594B2 (en) 2015-07-24 2020-03-03 Novozymes, Inc. Polypeptides having arabinofuranosidase activity and polynucleotides encoding same
US20180216089A1 (en) 2015-07-24 2018-08-02 Novozymes, Inc. Polypeptides Having Beta-Xylosidase Activity And Polynucleotides Encoding Same
JP7007261B2 (ja) 2015-08-20 2022-01-24 アルブミディクス リミティド アルブミン変異体及びコンジュゲート
EP3341475A1 (en) 2015-08-24 2018-07-04 Novozymes A/S Beta-alanine aminotransferases for the production of 3-hydroxypropionic acid
BR112018003782A2 (pt) 2015-08-27 2018-09-25 Ipsen Pharma Sas composições e métodos para o tratamento da dor
US10479984B2 (en) 2015-09-22 2019-11-19 Novozymes A/S Polypeptides having cellobiohydrolase activity and polynucleotides encoding same
GB201517450D0 (en) 2015-10-02 2015-11-18 Ipsen Biopharm Ltd Method
WO2017060662A1 (en) 2015-10-07 2017-04-13 The Secretary Of State For Health Method for providing a control for use in a screen for pathogenic virus
EP3359657B1 (en) 2015-10-07 2020-04-01 Novozymes A/S Polypeptides
US10494685B2 (en) 2015-10-14 2019-12-03 Novozymes A/S Glucoamylase variants and polynucleotides encoding same
EP4324919A3 (en) 2015-10-14 2024-05-29 Novozymes A/S Polypeptide variants
EP3362558A1 (en) 2015-10-14 2018-08-22 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
JP2018531783A (ja) 2015-10-14 2018-11-01 ノボザイムス アクティーゼルスカブ 水濾過膜の洗浄
WO2017070219A1 (en) 2015-10-20 2017-04-27 Novozymes A/S Lytic polysaccharide monooxygenase (lpmo) variants and polynucleotides encoding same
CN108291178B (zh) 2015-10-28 2020-08-04 诺维信公司 包含淀粉酶变体和蛋白酶变体的洗涤剂组合物
WO2017089366A1 (en) 2015-11-24 2017-06-01 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
WO2017093318A1 (en) 2015-12-01 2017-06-08 Novozymes A/S Methods for producing lipases
US10035995B2 (en) 2015-12-07 2018-07-31 Eastman Chemical Company CALB variants
ES2932192T3 (es) 2015-12-07 2023-01-16 Henkel Ag & Co Kgaa Composiciones para el lavado de vajilla que comprenden polipéptidos que tienen actividad beta-glucanasa y sus usos
EP3394243A1 (en) 2015-12-22 2018-10-31 Albumedix Ltd. Improved protein expression strains
JP7146637B2 (ja) 2015-12-22 2022-10-04 アルブミディクス リミティド 改善されたタンパク質発現株
US11407986B2 (en) 2015-12-30 2022-08-09 Novozymes A/S Enzyme variants and polynucleotides encoding same
MX2018008051A (es) 2016-01-29 2018-08-23 Novozymes As Variantes de beta-glucanasa y polinucleotidos que las codifican.
WO2017140807A1 (en) 2016-02-16 2017-08-24 Monaghan Mushrooms Group Fungal polypeptides having lysozyme activity
BR112018067371A2 (pt) 2016-03-02 2019-01-15 Novozymes As variante de celobio-hidrolase, composição de enzimas, formulação de caldo inteiro ou composição de cultura de células, polinucleotídeo, célula hospedeira recombinante, planta, parte de planta ou célula de planta transgênica, métodos para produção e para obtenção de uma variante de celobio-hidrolase, planta trangênica, e, processos para degradação de um material celulósico, para produção de um produto de fermentação e para fermentação de um material celulósico
US11965189B2 (en) 2016-03-24 2024-04-23 Novozymes A/S Cellobiohydrolase variants and polynucleotides encoding same
CN109414474B (zh) 2016-04-29 2024-07-02 诺维信公司 肝脏、胆道和胰腺障碍的治疗
CN109415421B (zh) 2016-05-03 2023-02-28 诺维信公司 α-淀粉酶变体以及编码它们的多核苷酸
CN109312319B (zh) 2016-05-09 2023-05-16 诺维信公司 具有改善的性能的变体多肽及其用途
EP3246401A1 (en) 2016-05-20 2017-11-22 Commissariat À L'Énergie Atomique Et Aux Énergies Alternatives New fatty acid decarboxylase and its uses
BR112018073890A2 (pt) 2016-05-24 2019-02-26 Novozymes As composição, grânulo, aditivo de ração para animal, ração para animal, formulação líquida, uso da composição, do grânulo, do aditivo de ração para animal ou da formulação líquida, polipeptídeo isolado, métodos para liberar galactose de material à base de planta, para melhorar um ou mais parâmetros de desempenho de um animal e para produzir o polipeptídeo, polinucleotídeo, construto de ácido nucleico ou vetor de expressão, e, célula hospedeira recombinante.
US10808268B2 (en) 2016-05-24 2020-10-20 Novozymes A/S Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
CN109196098A (zh) 2016-05-24 2019-01-11 诺维信公司 包含具有半乳聚糖酶活性的多肽和具有β-半乳糖苷酶活性的多肽的组合物
WO2017202979A1 (en) 2016-05-24 2017-11-30 Novozymes A/S Polypeptides having alpha-galactosidase activity and polynucleotides encoding same
WO2017205535A1 (en) 2016-05-27 2017-11-30 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
WO2017210188A1 (en) 2016-05-31 2017-12-07 Novozymes A/S Stabilized liquid peroxide compositions
CN109715792A (zh) 2016-06-03 2019-05-03 诺维信公司 枯草杆菌酶变体和对其进行编码的多核苷酸
WO2017211803A1 (en) 2016-06-07 2017-12-14 Novozymes A/S Co-expression of heterologous polypeptides to increase yield
US11203732B2 (en) 2016-06-30 2021-12-21 Novozymes A/S Lipase variants and compositions comprising surfactant and lipase variant
WO2018002379A2 (en) 2016-07-01 2018-01-04 Novozymes A/S Enzymatic preparation of indigo dyes and in situ dyeing process
WO2018002261A1 (en) 2016-07-01 2018-01-04 Novozymes A/S Detergent compositions
US10662417B2 (en) 2016-07-05 2020-05-26 Novozymes A/S Pectate lyase variants and polynucleotides encoding same
WO2018007153A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Polypeptides having xylanase activity and polynucleotides encoding same
CA3029113A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Xylanase variants and polynucleotides encoding same
WO2018007573A1 (en) 2016-07-08 2018-01-11 Novozymes A/S Detergent compositions with galactanase
CA3027272C (en) 2016-07-13 2022-06-21 The Procter & Gamble Company Bacillus cibi dnase variants and uses thereof
EP3485008B1 (en) 2016-07-18 2024-01-31 Novozymes A/S Lipase variants, polynucleotides encoding same and the use thereof
CN109477083B (zh) 2016-07-20 2023-06-06 诺维信公司 热稳定性宏基因组碳酸酐酶及其用途
EP3487995B1 (en) 2016-07-21 2021-05-26 Novozymes A/S Serine protease variants and polynucleotides encoding same
EP3487996B1 (en) 2016-07-21 2024-04-10 Novozymes A/S Serine protease variants and polynucleotides encoding same
WO2018015444A1 (en) 2016-07-22 2018-01-25 Novozymes A/S Crispr-cas9 genome editing with multiple guide rnas in filamentous fungi
WO2018026868A1 (en) 2016-08-01 2018-02-08 Novozymes, Inc. Polypeptides having endoglucanase activity and polynucleotides encoding same
US11512300B2 (en) 2016-08-24 2022-11-29 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
WO2018037065A1 (en) 2016-08-24 2018-03-01 Henkel Ag & Co. Kgaa Detergent composition comprising gh9 endoglucanase variants i
CN109563498A (zh) 2016-08-24 2019-04-02 汉高股份有限及两合公司 包含黄原胶裂解酶变体i的洗涤剂组合物
CA3031609A1 (en) 2016-08-24 2018-03-01 Novozymes A/S Gh9 endoglucanase variants and polynucleotides encoding same
WO2018060475A1 (en) 2016-09-29 2018-04-05 Novozymes A/S Spore containing granule
US20210284933A1 (en) 2016-10-25 2021-09-16 Novozymes A/S Detergent compositions
WO2018085370A1 (en) 2016-11-02 2018-05-11 Novozymes A/S Processes for reducing production of primeverose during enzymatic saccharification of lignocellulosic material
US11208474B2 (en) 2016-11-16 2021-12-28 Janssen Biotech, Inc. Method of treating psoriasis with anti-IL23 specific antibody
WO2018094181A1 (en) 2016-11-21 2018-05-24 Novozymes A/S Yeast cell extract assisted construction of dna molecules
CN110072997A (zh) 2016-11-23 2019-07-30 诺维信公司 具有蛋白酶活性的多肽和编码其的多核苷酸
EP3548615A1 (en) 2016-11-29 2019-10-09 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
US11229214B2 (en) 2016-11-30 2022-01-25 Novozymes A/S Method of baking
EP3551759A1 (en) 2016-12-06 2019-10-16 Novozymes A/S Improved processes for production of ethanol from xylose-containing cellulosic substrates using engineered yeast strains
MX2019006848A (es) 2016-12-13 2019-10-07 Defensin Therapeutics Aps Metodos para tratar condiciones inflamatorias de los pulmones.
EP4624568A3 (en) 2016-12-20 2025-10-22 Novozymes A/S Recombinant yeast strains for pentose fermentation
US10986850B2 (en) 2016-12-21 2021-04-27 Novozymes A/S Polypeptides having lysozyme activity, polynucleotides encoding same and uses and compositions thereof
WO2018140121A1 (en) 2017-01-30 2018-08-02 Janssen Biotech, Inc. Anti-tnf antibodies, compositions, and methods for the treatment of active psoriatic arthritis
US12071643B2 (en) 2017-02-01 2024-08-27 Novozymes A/S Alpha-amylase variants
ES2965826T3 (es) 2017-02-01 2024-04-17 Procter & Gamble Composiciones limpiadoras que comprenden variantes de amilasa
MX2019009377A (es) 2017-02-07 2019-12-11 Janssen Biotech Inc Anticuerpos anti-tnf, composiciones y metodos para el tratamiento de la espondilitis anquilosante activa.
BR112019017271A2 (pt) 2017-02-20 2020-04-14 Novozymes As enzima lipolítica para uso em panificação
CA3055530A1 (en) 2017-03-07 2018-09-13 Danisco Us Inc. Thermostable glucoamylase and methods of use, thereof
CA3056920A1 (en) 2017-03-29 2018-10-04 Boehringer Ingelheim Rcv Gmbh & Co Kg Recombinant host cell with altered membrane lipid composition
US11149233B2 (en) 2017-03-31 2021-10-19 Novozymes A/S Polypeptides having RNase activity
WO2018177936A1 (en) 2017-03-31 2018-10-04 Novozymes A/S Polypeptides having dnase activity
US11208639B2 (en) 2017-03-31 2021-12-28 Novozymes A/S Polypeptides having DNase activity
CN110651040A (zh) 2017-03-31 2020-01-03 诺维信公司 具有dna酶活性的多肽
CN114480034A (zh) 2017-04-04 2022-05-13 诺维信公司 糖基水解酶
EP3607039A1 (en) 2017-04-04 2020-02-12 Novozymes A/S Polypeptides
EP3607040A1 (en) 2017-04-04 2020-02-12 Novozymes A/S Polypeptide compositions and uses thereof
BR112019021223A2 (pt) 2017-04-11 2020-04-28 Novozymes A/S variante de glucoamilase, métodos para aumentar a atividade de hidrólise de amido em bruto de uma glucoamilase e para produzir uma variante de glucoamilase, composição, uso de uma variante de glucoamilase, processos para produzir um produto de fermentação e para produzir um produto de xarope, polinucleotídeo codificando a variante de glucoamilase, construto de ácido nucleico, vetor de expressão, e, célula hospedeira.
WO2018202846A1 (en) 2017-05-05 2018-11-08 Novozymes A/S Compositions comprising lipase and sulfite
CA3058092A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2018206302A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Mannanase variants and polynucleotides encoding same
EP3401385A1 (en) 2017-05-08 2018-11-14 Henkel AG & Co. KGaA Detergent composition comprising polypeptide comprising carbohydrate-binding domain
WO2018206535A1 (en) 2017-05-08 2018-11-15 Novozymes A/S Carbohydrate-binding domain and polynucleotides encoding the same
US11091753B2 (en) 2017-05-31 2021-08-17 Novozymes A/S Xylose fermenting yeast strains and processes thereof for ethanol production
CN110730824A (zh) 2017-06-02 2020-01-24 诺维信公司 用于乙醇生产的改善的酵母
WO2018224544A1 (en) 2017-06-08 2018-12-13 Novozymes A/S Compositions comprising polypeptides having cellulase activity and amylase activity, and uses thereof in cleaning and detergent compositions
WO2018224035A1 (en) 2017-06-09 2018-12-13 Novozymes A/S Polypeptide, use and method for hydrolysing protein
US11130979B2 (en) 2017-06-20 2021-09-28 Albumedix Ltd Protein expression strains
US11499144B2 (en) 2017-06-22 2022-11-15 Novozymes A/S Xylanase variants and polynucleotides encoding same
US11584783B2 (en) 2017-06-28 2023-02-21 Novozymes A/S Processes for producing a fermentation product
EP3645692B1 (en) 2017-06-30 2025-12-31 Novozymes A/S ENZYMATIC SUSPENSION COMPOSITION
EP3658610B1 (en) 2017-07-24 2023-10-25 Novozymes A/S Gh5 and gh30 in wet milling
US11220679B2 (en) 2017-08-08 2022-01-11 Novozymes A/S Polypeptides having trehalase activity
US11624059B2 (en) 2017-08-24 2023-04-11 Henkel Ag & Co. Kgaa Detergent compositions comprising GH9 endoglucanase variants II
US11359188B2 (en) 2017-08-24 2022-06-14 Novozymes A/S Xanthan lyase variants and polynucleotides encoding same
CA3070749A1 (en) 2017-08-24 2019-02-28 Novozymes A/S Gh9 endoglucanase variants and polynucleotides encoding same
US20210130744A1 (en) 2017-08-24 2021-05-06 Henkel Ag & Co. Kgaa Detergent composition comprising xanthan lyase variants ii
AU2018322748B2 (en) 2017-08-29 2024-05-02 Novozymes A/S Baker's yeast expressing anti-staling/freshness amylases
EP4603591A3 (en) 2017-08-31 2025-10-22 Novozymes A/S Polypeptides having d-psicose 3-epimerase activity and polynucleotides encoding same
WO2019046703A1 (en) 2017-09-01 2019-03-07 Novozymes A/S METHODS OF ENHANCING GENOME EDITION IN FUNGI
EP4501130A3 (en) 2017-09-01 2025-04-23 Novozymes A/S Animal feed additives comprising a polypeptide having protease activity and uses thereof
AU2018322865B2 (en) 2017-09-01 2023-11-09 Novozymes A/S Animal feed additives comprising polypeptide having protease activity and uses thereof
WO2019047199A1 (en) 2017-09-11 2019-03-14 Danisco Us Inc. GLUCOAMYLASE AND METHODS OF USE THEREOF
TW201922780A (zh) 2017-09-25 2019-06-16 美商健生生物科技公司 以抗il12/il23抗體治療狼瘡之安全且有效之方法
JP7114697B2 (ja) 2017-09-27 2022-08-08 ザ プロクター アンド ギャンブル カンパニー リパーゼを含む洗剤組成物
EP4567094A3 (en) 2017-09-27 2026-01-07 Novozymes A/S Lipase variants and microcapsule compositions comprising such lipase variants
US11746310B2 (en) 2017-10-02 2023-09-05 Novozymes A/S Polypeptides having mannanase activity and polynucleotides encoding same
CN111373036A (zh) 2017-10-02 2020-07-03 诺维信公司 具有甘露聚糖酶活性的多肽和编码它们的多核苷酸
CN111148830A (zh) 2017-10-04 2020-05-12 诺维信公司 具有蛋白酶活性的多肽和编码其的多核苷酸
CN111417726A (zh) 2017-10-23 2020-07-14 诺维信公司 通过与前肽共表达改善蛋白酶的表达
HUE057832T2 (hu) 2017-10-27 2022-06-28 Procter & Gamble Polipeptid-variánsokat tartalmazó mosószerkészítmények
EP3701017A1 (en) 2017-10-27 2020-09-02 Novozymes A/S Dnase variants
DE102017125558A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine i enthalten
DE102017125559A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine ii enthalten
DE102017125560A1 (de) 2017-11-01 2019-05-02 Henkel Ag & Co. Kgaa Reinigungszusammensetzungen, die dispersine iii enthalten
JP2021502349A (ja) 2017-11-06 2021-01-28 ヤンセン バイオテツク,インコーポレーテツド 抗il23特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法
EP3707252A1 (en) 2017-11-10 2020-09-16 Novozymes A/S Temperature-sensitive cas9 protein
MX2020004863A (es) 2017-11-10 2020-10-14 Defensin Therapeutics Aps Maduracion de la defensa de la mucosa y/o funcion intestinal/pulmonar en el bebe prematuro.
EP3710580A1 (en) 2017-11-14 2020-09-23 Danisco US Inc. Alpha-amylase, composition and method
WO2019096903A1 (en) 2017-11-20 2019-05-23 Novozymes A/S New galactanases (ec 3.2.1.89) for use in soy processing
PL3713590T3 (pl) 2017-11-24 2025-09-15 Defensin Therapeutics Aps Ludzka beta 2 defensyna do stosowania w zapobieganiu i leczeniu choroby przeszczep przeciwko gospodarzowi
CN111670248A (zh) 2017-12-04 2020-09-15 诺维信公司 脂肪酶变体以及编码其的多核苷酸
DK3720955T5 (da) 2017-12-08 2024-08-26 Novozymes As Alfa-amylasevarianter og polynukleotider, der koder for dem
BR112020011173A2 (pt) 2017-12-08 2020-11-17 Novozymes A/S variante de alfa-amilase, polinucleotídeo, composição, construto de ácido nucleico, vetor de expressão, célula hospedeira, método de produção de uma variante de alfa-amilase, uso da variante, e, processo para produção de um xarope a partir de material contendo amido.
EP3728574A1 (en) 2017-12-20 2020-10-28 Basf Se Nucleases and methods for making and using them
CA3083854A1 (en) 2017-12-22 2019-06-27 Novozymes A/S Wheat milling process and gh8 xylanases
EP3746545A1 (en) 2018-01-29 2020-12-09 Novozymes A/S Microorganisms with improved nitrogen utilization for ethanol production
EP3749759A1 (en) 2018-02-08 2020-12-16 Novozymes A/S Lipase variants and compositions thereof
WO2019154951A1 (en) 2018-02-08 2019-08-15 Novozymes A/S Lipases, lipase variants and compositions thereof
CN111684056A (zh) 2018-02-28 2020-09-18 宝洁公司 清洁方法
MX2020009265A (es) 2018-03-05 2020-10-01 Janssen Biotech Inc Metodos para tratar la enfermedad de crohn con un anticuerpo especifico anti-il23.
CA3093378A1 (en) 2018-03-09 2019-09-12 Danisco Us Inc Glucoamylases and methods of use thereof
US20210002588A1 (en) 2018-03-13 2021-01-07 Novozymes A/S Microencapsulation Using Amino Sugar Oligomers
EP3775190A1 (en) 2018-03-29 2021-02-17 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2019197318A1 (en) 2018-04-09 2019-10-17 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
CN118460512A (zh) 2018-04-19 2024-08-09 诺维信公司 稳定化的纤维素酶变体
EP3781680A1 (en) 2018-04-19 2021-02-24 Novozymes A/S Stabilized cellulase variants
CN112165955A (zh) 2018-05-21 2021-01-01 益普生生物制药有限公司 抑制骨癌引起的异常性疼痛
BR112020022593A2 (pt) 2018-05-31 2021-02-09 Novozymes A/S método para tratar polpa de dissolução, polpa de dissolução, fibra têxtil ou celulose derivatizada, e, uso de uma monoxigenase lítica de polissacarídeo.
GB201809135D0 (en) 2018-06-04 2018-07-18 Sec Dep For Health Methods for detecting anitviral-drug resistant virus
WO2019243376A1 (en) 2018-06-18 2019-12-26 Ipsen Biopharm Limited Intramuscular injection of botulinum toxin for the treatment of vulvodynia
JP7645076B2 (ja) 2018-06-27 2025-03-13 ベーリンガー インゲルハイム エルツェーファウ ゲゼルシャフト ミット ベシュレンクテル ハフツング ウント コンパニー コマンディトゲゼルシャフト 転写因子の使用によってタンパク質発現を増加させるための手段及び方法
WO2020002575A1 (en) 2018-06-28 2020-01-02 Novozymes A/S Polypeptides having pectin lyase activity and polynucleotides encoding same
CA3105609A1 (en) 2018-07-04 2020-01-09 Danisco Us Inc Glucoamylases and methods of use, thereof
US20200025776A1 (en) 2018-07-18 2020-01-23 Janssen Biotech, Inc. Sustained Response Predictors After Treatment With Anti-IL23 Specific Antibody
MX2021000893A (es) 2018-07-25 2021-03-31 Novozymes As Levadura que expresa enzimas para la producción de etanol.
GB201812261D0 (en) 2018-07-27 2018-09-12 Micropharm Ltd Therapies for treating oral mucositis
GB201812262D0 (en) 2018-07-27 2018-09-12 Micropharm Ltd Therapies for treating proctitis
GB201813884D0 (en) 2018-08-24 2018-10-10 Sec Dep For Health Culture media
US11473076B2 (en) 2018-08-31 2022-10-18 Novozymes A/S Animal feed additives and compositions comprising an S8 serine protease
IL326284A (en) 2018-09-24 2026-04-01 Janssen Biotech Inc A safe and effective method for treating ulcerative colitis with an anti-IL12/IL23 antibody
GB201815817D0 (en) 2018-09-28 2018-11-14 Ispen Biopharm Ltd Clostridial neurotoxins comprising and exogenous activation loop
GB201815844D0 (en) 2018-09-28 2018-11-14 Ipsen Biopharm Ltd Therapeutic & comestic uses of botulinum neurotoxin serotype e
CA3111674A1 (en) 2018-09-28 2020-04-02 Ipsen Biopharm Limited Cell-based clostridal neurotoxin assays
WO2020070199A1 (en) 2018-10-03 2020-04-09 Novozymes A/S Polypeptides having alpha-mannan degrading activity and polynucleotides encoding same
WO2020070461A1 (en) 2018-10-04 2020-04-09 Secretary of State for Health and Social Care Immunoassay for detection of streptococcus pneumoniae serotypes
CN113286889A (zh) 2018-10-08 2021-08-20 诺维信公司 用于生产乙醇的表达酶的酵母
EP3874051A1 (en) 2018-10-31 2021-09-08 Novozymes A/S Genome editing by guided endonuclease and single-stranded oligonucleotide
IL283192B2 (en) 2018-11-20 2025-10-01 Janssen Biotech Inc A safe and effective method for treating psoriasis with a specific anti-IL-23 antibody
US20220016221A1 (en) 2018-12-05 2022-01-20 Ipsen Biopharm Limited Treatment of symptoms of traumatic brain injury
BR112021011384A2 (pt) 2018-12-12 2022-05-17 Novozymes As Polipeptídeo isolado, composição de enzimas, formulação de caldo inteiro ou composição de cultura de células, polinucleotídeo isolado, célula hospedeira recombinante, método de produção de um polipeptídeo, planta, parte da planta ou célula da planta transgênica, e, processos para degradação de um material celulósico ou hemicelulósico, para produção de um produto de fermentação e de fermentação de um material celulósico ou hemicelulósico
MA54562A (fr) 2018-12-18 2021-10-27 Janssen Biotech Inc Méthode sûre et efficace de traitement du lupus avec un anticorps anti-il12/il23
CN113366103A (zh) 2018-12-21 2021-09-07 诺维信公司 具有肽聚糖降解活性的多肽以及编码其的多核苷酸
GB201900621D0 (en) 2019-01-16 2019-03-06 Ipsen Biopharm Ltd Labelled polypeptides
BR112021014873A2 (pt) 2019-01-31 2021-10-05 Novozymes A/S Polipeptídeo, combinação de enzimas, polinucleotídeo, construto de ácido nucleico ou vetor de expressão recombinante, célula hospedeira recombinante, método de produção de um polipeptídeo, e, processo de produção de um produto de fermentação
EP3938384A4 (en) 2019-03-14 2022-12-28 Janssen Biotech, Inc. PREPARATION PROCEDURES FOR THE PREPARATION OF ANTI-IL12/IL23 ANTIBODY COMPOSITIONS
KR20210141998A (ko) 2019-03-14 2021-11-23 얀센 바이오테크 인코포레이티드 항-tnf 항체 조성물의 제조 방법
WO2020183269A1 (en) 2019-03-14 2020-09-17 Janssen Biotech, Inc. Manufacturing methods for producing anti-tnf antibody compositions
EA202192505A1 (ru) 2019-03-14 2022-03-29 Янссен Байотек, Инк. Способы получения композиций антитела к фно
JP2022526493A (ja) 2019-03-18 2022-05-25 ヤンセン バイオテツク,インコーポレーテツド 抗il12/il23抗体を用いた小児被験者の乾癬の治療方法
JP7725365B2 (ja) 2019-03-21 2025-08-19 ノボザイムス アクティーゼルスカブ α-アミラーゼ変異体及びこれをコードするポリヌクレオチド
CN114096559B (zh) 2019-03-27 2026-03-20 蒂嘉特克斯公司 工程化iga抗体及其使用方法
WO2020201403A1 (en) 2019-04-03 2020-10-08 Novozymes A/S Polypeptides having beta-glucanase activity, polynucleotides encoding same and uses thereof in cleaning and detergent compositions
US12247237B2 (en) 2019-04-10 2025-03-11 Novozymes A/S Polypeptide variants
WO2020208056A1 (en) 2019-04-12 2020-10-15 Novozymes A/S Stabilized glycoside hydrolase variants
CN113939588A (zh) 2019-05-15 2022-01-14 诺维信公司 温度敏感性的rna指导的内切核酸酶
GB201907016D0 (en) 2019-05-17 2019-07-03 Ipsen Biopharm Ltd Screening method to determine suitability for participation in a clinical trial
JP7805788B2 (ja) 2019-05-23 2026-01-26 ヤンセン バイオテツク,インコーポレーテツド Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
MA56124A (fr) 2019-06-04 2022-04-13 Janssen Biotech Inc Méthode sûre et efficace de traitement de l'arthrite psoriasique au moyen d'un anticorps spécifique anti-il23
GB201908155D0 (en) 2019-06-07 2019-07-24 Univ Warwick Leader sequence
WO2020260223A1 (en) 2019-06-24 2020-12-30 Novozymes A/S Alpha-amylase variants
MX2021015382A (es) 2019-06-24 2022-01-24 Procter & Gamble Composiciones de limpieza que comprenden variantes de amilasa.
EP3994255A1 (en) 2019-07-02 2022-05-11 Novozymes A/S Lipase variants and compositions thereof
GB201909619D0 (en) 2019-07-04 2019-08-21 Univ Oxford Innovation Ltd Methods for diagnosing multiple sclerosis
CN114391038A (zh) 2019-07-25 2022-04-22 诺维信公司 丝状真菌表达系统
WO2021021458A1 (en) 2019-07-26 2021-02-04 Novozymes A/S Microorganisms with improved nitrogen transport for ethanol production
BR112022001394A2 (pt) 2019-07-26 2022-03-22 Novozymes As Tratamento enzimático de polpa de papel
GB201911064D0 (en) 2019-08-02 2019-09-18 Tarian Biologics Ltd Therapy
GB201911063D0 (en) 2019-08-02 2019-09-18 Tarian Biologics Ltd Formulations
MX2021015818A (es) 2019-08-06 2022-02-03 Novozymes As Proteinas de fusion para mejorar la expresion de enzimas.
CN114364795A (zh) 2019-08-22 2022-04-15 巴斯夫欧洲公司 淀粉酶变体
EP4031661A1 (en) 2019-09-16 2022-07-27 Novozymes A/S Polypeptides having beta-glucanase activity and polynucleotides encoding same
GB201913804D0 (en) 2019-09-25 2019-11-06 Prostate Cancer Res Centre Fusion polypeptides
GB201914034D0 (en) 2019-09-30 2019-11-13 Ipsen Biopharm Ltd Treatment of neurological disorders
WO2021064068A1 (en) 2019-10-03 2021-04-08 Novozymes A/S Polypeptides comprising at least two carbohydrate binding domains
CA3158982A1 (en) 2019-12-10 2021-06-17 Monica TASSONE Microorganism for improved pentose fermentation
GB201918313D0 (en) 2019-12-12 2020-01-29 Lift Biosciences Ltd Cells for treating cancer
GB201918341D0 (en) 2019-12-12 2020-01-29 Lift Biosciences Ltd Cells for treating infections
CN115023422A (zh) 2019-12-12 2022-09-06 德国费森尤斯卡比有限公司 糖基化多肽
JP2023506305A (ja) 2019-12-19 2023-02-15 ノボザイムス アクティーゼルスカブ キシラナーゼバリアント及びそれをコードするポリヌクレオチド
WO2021123184A2 (en) 2019-12-19 2021-06-24 Novozymes A/S Alpha-amylase variants
CA3160401C (en) 2019-12-19 2025-06-10 The Procter & Gamble Company CLEANING COMPOSITIONS COMPRISING POLYPEPTIDES HAVING ALPHA-AMYLASE ACTIVITY
US20220411773A1 (en) 2019-12-20 2022-12-29 Novozymes A/S Polypeptides having proteolytic activity and use thereof
WO2021148278A1 (en) 2020-01-24 2021-07-29 Novozymes A/S Mutants of a filamentous fungal cell having increased productivity in the production of a polypeptide
EP4097227A1 (en) 2020-01-31 2022-12-07 Novozymes A/S Mannanase variants and polynucleotides encoding same
GB202001353D0 (en) 2020-01-31 2020-03-18 Ipsen Biopharm Ltd Treatment of skin conditions
WO2021152120A1 (en) 2020-01-31 2021-08-05 Novozymes A/S Mannanase variants and polynucleotides encoding same
EP4103709A2 (en) 2020-02-10 2022-12-21 Novozymes A/S Polypeptides having alpha-amylase activity and polynucleotides encoding same
US20230235367A1 (en) 2020-02-10 2023-07-27 Novozymes A/S Process for producing ethanol from raw starch using alpha-amylase variants
US20230142991A1 (en) 2020-02-10 2023-05-11 Novozymes A/S Alpha-amylase variants and polynucleotides encoding same
GB2594683A (en) 2020-02-17 2021-11-10 Vaxbio Ltd Vaccine
EP4110909A1 (en) 2020-02-26 2023-01-04 Novozymes A/S Polypeptide variants
GB202003611D0 (en) 2020-03-12 2020-04-29 Univ Oxford Innovation Ltd Stabilised viral fusion proteins
TWI825396B (zh) 2020-03-16 2023-12-11 英商艾普森生物製藥有限公司 肢體痙攣之治療
GB202003813D0 (en) 2020-03-16 2020-04-29 Ipsen Biopharm Ltd Treatment of upper facial lines
WO2021204838A1 (en) 2020-04-08 2021-10-14 Novozymes A/S Carbohydrate binding module variants
CN115867651A (zh) 2020-04-17 2023-03-28 丹尼斯科美国公司 葡糖淀粉酶及其使用方法
US20230167384A1 (en) 2020-04-21 2023-06-01 Novozymes A/S Cleaning compositions comprising polypeptides having fructan degrading activity
US20210347880A1 (en) 2020-05-05 2021-11-11 Janssen Biotech, Inc. Methods of Treating Crohn's Disease with Anti-IL23 Specific Antibody
GB202006803D0 (en) 2020-05-07 2020-06-24 Imperial College Innovations Ltd Method for identifying RNA binding protein binding sites on RNA
IL298389A (en) 2020-05-21 2023-01-01 Janssen Biotech Inc Method of treating inflammatory bowel disease with a combination therapy of antibodies to il-23 and tnf alpha
WO2021260193A1 (en) 2020-06-25 2021-12-30 Medimmune Limited Prevention of axonal damage using antibody binding to amyloid beta 1-42
GB2596820A (en) 2020-07-07 2022-01-12 Spicona Inc Combination vaccine
WO2022013745A1 (en) 2020-07-13 2022-01-20 Janssen Biotech, Inc. Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody
GB202010934D0 (en) 2020-07-15 2020-08-26 Ipsen Biopharm Ltd Controlling operation of a bioreactor vessel
GB202011055D0 (en) 2020-07-17 2020-09-02 Ipsen Bioinnovation Ltd Treatment of post-operative pain
WO2022013574A1 (en) 2020-07-17 2022-01-20 Imperial College Innovations Limited Hybrid double antigen sars-cov-2 antibody detection assay
US20220073603A1 (en) 2020-07-30 2022-03-10 Janssen Biotech, Inc. Method of Treating Psoriasis in Pediatric Subjects with Anti-IL12/IL23 Antibody
GB202011902D0 (en) 2020-07-30 2020-09-16 Imperial College Innovations Ltd Antinobacillus pleuropneumoniae vaccines
US20230313209A1 (en) 2020-08-18 2023-10-05 Novozymes A/S Dispersins expressed with amylase signal peptides
EP4204551B1 (en) 2020-08-25 2025-09-17 Novozymes A/S Variants of a family 44 xyloglucanase
WO2022043563A1 (en) 2020-08-28 2022-03-03 Novozymes A/S Polyester degrading protease variants
WO2022049403A1 (en) 2020-09-07 2022-03-10 Imperial College Innovations Limited Sars-cov-2 antibody detection assay
BR112023004415A2 (pt) 2020-09-11 2023-05-09 Medimmune Ltd Moléculas terapêuticas de ligação a b7-h4
JP2023540630A (ja) 2020-09-14 2023-09-25 アエスクルス バイオ エーピーエス 薬物耐性微生物の処置のためのデフェンシン断片由来のリポペプチド
JP2023541632A (ja) 2020-09-15 2023-10-03 インペリアル・カレッジ・イノベーションズ・リミテッド 特発性肺線維症の処置
GB202015618D0 (en) 2020-10-01 2020-11-18 Ipsen Biopharm Ltd Method for producing beta-trypsin
US20250346879A1 (en) 2020-10-07 2025-11-13 Novozymes A/S Alpha-amylase variants
EP4229189A1 (en) 2020-10-13 2023-08-23 Novozymes A/S Glycosyltransferase variants for improved protein production
GB202016349D0 (en) 2020-10-15 2020-12-02 Imp College Innovations Ltd Proteome analysis in pulmonary hypertension
WO2022090320A1 (en) 2020-10-28 2022-05-05 Novozymes A/S Use of lipoxygenase
JP2023547450A (ja) 2020-10-29 2023-11-10 ノボザイムス アクティーゼルスカブ リパーゼ変異体及びそのようなリパーゼ変異体を含む組成物
CN116438309A (zh) 2020-11-02 2023-07-14 诺维信公司 葡糖淀粉酶变体和编码它们的多核苷酸
WO2022090555A1 (en) 2020-11-02 2022-05-05 Novozymes A/S Leader peptides and polynucleotides encoding the same
GB202017673D0 (en) 2020-11-09 2020-12-23 Imperial College Innovations Ltd Treatment of pulmonary arterial hypertensive
WO2022106404A1 (en) 2020-11-18 2022-05-27 Novozymes A/S Combination of proteases
WO2022106400A1 (en) 2020-11-18 2022-05-27 Novozymes A/S Combination of immunochemically different proteases
CN116710471A (zh) 2020-12-15 2023-09-05 诺维信公司 具有减少的细胞运动的突变的宿主细胞
WO2023288294A1 (en) 2021-07-16 2023-01-19 Novozymes A/S Compositions and methods for improving the rainfastness of proteins on plant surfaces
GB202100566D0 (en) 2021-01-15 2021-03-03 Ipsen Biopharm Ltd Treatment of brain damage
US20240124805A1 (en) 2021-01-28 2024-04-18 Novozymes A/S Lipase with low malodor generation
EP4291646A2 (en) 2021-02-12 2023-12-20 Novozymes A/S Alpha-amylase variants
WO2022175440A1 (en) 2021-02-18 2022-08-25 Novozymes A/S Inactive heme polypeptides
EP4047088A1 (en) 2021-02-22 2022-08-24 Basf Se Amylase variants
MX2023009756A (es) 2021-02-22 2023-09-04 Basf Se Variantes de amilasa.
GB202102832D0 (en) 2021-02-26 2021-04-14 Ip2Ipo Innovations Ltd Retroviral vectors
GB202103372D0 (en) 2021-03-11 2021-04-28 Ipsen Biopharm Ltd Modified clostridial neurotoxins
EP4305146A1 (en) 2021-03-12 2024-01-17 Novozymes A/S Polypeptide variants
EP4060036A1 (en) 2021-03-15 2022-09-21 Novozymes A/S Polypeptide variants
WO2022194673A1 (en) 2021-03-15 2022-09-22 Novozymes A/S Dnase variants
EP4060010A3 (en) 2021-03-15 2022-12-07 The Procter & Gamble Company Cleaning compositions containing polypeptide variants
IL305690B2 (en) 2021-03-18 2025-10-01 Medimmune Ltd A therapeutic binding molecule that binds to CCR9
GB202104294D0 (en) 2021-03-26 2021-05-12 Ipsen Biopharm Ltd Clostridial neurotoxins comprising an exogenous activation loop
WO2022199418A1 (en) 2021-03-26 2022-09-29 Novozymes A/S Detergent composition with reduced polymer content
KR20230155007A (ko) 2021-03-30 2023-11-09 입센 바이오팜 리미티드 통증 & 염증성 장애의 치료를 위한 촉매 불활성 클로스트리디움 신경독소
JP2024513191A (ja) 2021-03-30 2024-03-22 イプセン バイオファーム リミテッド 疼痛及び炎症性障害の処置
US20240180197A1 (en) 2021-04-12 2024-06-06 Novozymes A/S Method for producing a meat analogue product
GB202105278D0 (en) 2021-04-13 2021-05-26 Imperial College Innovations Ltd Cell therapy
GB202105277D0 (en) 2021-04-13 2021-05-26 Imperial College Innovations Ltd Signal peptides
GB202105276D0 (en) 2021-04-13 2021-05-26 Imperial College Innovations Ltd Delivery of gene therapy vectors
US20250011809A1 (en) 2021-05-27 2025-01-09 Cell Therapy Catapult Limited Viral vector production
WO2022251056A1 (en) 2021-05-27 2022-12-01 Novozymes A/S Transcriptional regulators and polynucleotides encoding the same
AU2022288057A1 (en) 2021-06-07 2023-12-21 Novozymes A/S Engineered microorganism for improved ethanol fermentation
EP4355868A1 (en) 2021-06-16 2024-04-24 Novozymes A/S Method for controlling slime in a pulp or paper making process
US12534524B2 (en) 2021-07-09 2026-01-27 Janssen Biotech, Inc. Manufacturing methods for producing anti-TNF antibody compositions
EP4370534A1 (en) 2021-07-13 2024-05-22 Novozymes A/S Recombinant cutinase expression
EP4401759B1 (en) 2021-09-16 2026-02-18 Ipsen Biopharm Limited Modified bont/a for use in the treatment of cervical dystonia
EP4404955A1 (en) 2021-09-23 2024-07-31 Ipsen Biopharm Limited Modified bont/a for use in the treatment of a disorder affecting an eyelid muscle of a subject
GB202113602D0 (en) 2021-09-23 2021-11-10 Ipsen Biopharm Ltd Treatment of a disorder affecting an eyelid muscle of a subject
EP4416257A1 (en) 2021-10-12 2024-08-21 Novozymes A/S Endoglucanase with improved stability
US20250236858A1 (en) 2021-10-15 2025-07-24 Danisco Us Inc. Glucoamylase variants and methods for use thereof
US20250000816A1 (en) 2021-11-11 2025-01-02 Nutri-Gentix Limited Nutritional compositions
WO2023089343A1 (en) 2021-11-22 2023-05-25 Ipsen Biopharm Limited Treatment of pain
GB202116795D0 (en) 2021-11-22 2022-01-05 Ipsen Biopharm Ltd Treatment of visceral pain
EP4444859A1 (en) 2021-12-10 2024-10-16 Novozymes A/S Improved protein production in recombinant bacteria
AU2022422579A1 (en) 2021-12-21 2024-08-08 Imperial College Innovations Limited Pseudotyped lentiviral vectors
EP4451889A1 (en) 2021-12-22 2024-10-30 Novozymes A/S Method of producing a milk-based product
WO2023118565A1 (en) 2021-12-23 2023-06-29 Novozymes A/S Reduction of residual dna in microbial fermentation products
EP4475850A1 (en) 2022-02-09 2024-12-18 Imperial College Innovations Limited Treatment of telangiectasia
EP4476240A1 (en) 2022-02-10 2024-12-18 Novozymes A/S Improved expression of recombinant proteins
US20250161187A1 (en) 2022-02-22 2025-05-22 Novozymes A/S Oral care composition comprising enzymes
US20250179393A1 (en) 2022-03-02 2025-06-05 Novozymes A/S Use of xyloglucanase for improvement of sustainability of detergents
US20250215412A1 (en) 2022-03-08 2025-07-03 Novozymes A/S Fusion Polypeptides with Deamidase Inhibitor and Deamidase Domains
EP4242303A1 (en) 2022-03-08 2023-09-13 Novozymes A/S Fusion polypeptides with deamidase inhibitor and deamidase domains
EP4489859A1 (en) 2022-03-09 2025-01-15 Astrazeneca AB Binding molecules against fr alpha
KR20240162086A (ko) 2022-03-11 2024-11-14 아스트라제네카 아베 항-FRα 항체-약물 접합체 치료법에 대한 점수 산정 방법
CN119137279A (zh) 2022-04-11 2024-12-13 Ip2Ipo创新有限公司 组合治疗
GB202206353D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of cervical dystonia
GB202206362D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of upper facial lines
GB202206361D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of a facial dystonia
GB202206348D0 (en) 2022-04-29 2022-06-15 Ipsen Biopharm Ltd Treatment of limb spasticity
EP4525615A2 (en) 2022-05-14 2025-03-26 Novozymes A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections
WO2023222648A2 (en) 2022-05-17 2023-11-23 Novozymes A/S Process for reducing free fatty acids
WO2023247348A1 (en) 2022-06-21 2023-12-28 Novozymes A/S Mannanase variants and polynucleotides encoding same
WO2023247514A1 (en) 2022-06-22 2023-12-28 Novozymes A/S Recombinant mannanase expression
EP4544015A2 (en) 2022-06-24 2025-04-30 Novozymes A/S Lipase variants and compositions comprising such lipase variants
WO2024003143A1 (en) 2022-06-30 2024-01-04 Novozymes A/S Mutanases and oral care compositions comprising same
JP2025525309A (ja) 2022-07-15 2025-08-05 ノボザイムス アクティーゼルスカブ デアミダーゼ阻害剤活性を有するポリペプチド
WO2024033133A2 (en) 2022-08-11 2024-02-15 Basf Se Enzyme compositions comprising an amylase
JP2025526654A (ja) 2022-08-11 2025-08-15 ビーエーエスエフ ソシエタス・ヨーロピア プロテアーゼ、マンナナーゼ及び/又はセルラーゼを含む酵素組成物
GB202212472D0 (en) 2022-08-26 2022-10-12 Ip2Ipo Innovations Ltd Retroviral vectors
GB202213479D0 (en) 2022-09-14 2022-10-26 Ipsen Biopharm Ltd Cell-free clostridial neurotoxin assays
WO2024056643A1 (en) 2022-09-15 2024-03-21 Novozymes A/S Fungal signal peptides
GB202213936D0 (en) 2022-09-23 2022-11-09 Imperial College Innovations Ltd Introns
GB202214232D0 (en) 2022-09-28 2022-11-09 Ispen Biopharm Ltd Clostridial neurotoxins comprising an activating exogenous protease cleavage site
GB202214229D0 (en) 2022-09-28 2022-11-09 Ipsen Biopharm Ltd Clostridial neurotoxins comprising an activating endosomal protease cleavage site
GB202214445D0 (en) 2022-09-30 2022-11-16 Imp College Innovations Ltd Gene therapy
JP2025534349A (ja) 2022-09-30 2025-10-15 イプセン バイオファーム リミテッド 膀胱痛症候群の治療
GB202214720D0 (en) 2022-10-06 2022-11-23 Path Spray Ltd Compositions for detecting biological agents
AU2023400641A1 (en) 2022-11-30 2025-05-01 Novozymes A/S Carbonic anhydrase variants and polynucleotides encoding same
CN120265779A (zh) 2022-12-05 2025-07-04 诺维信公司 经修饰的rna聚合酶活性
JP2026508744A (ja) 2022-12-05 2026-03-12 ノボザイムス アクティーゼルスカブ プロテアーゼバリアント、及びそれをコードするポリヌクレオチド
CN120456823A (zh) 2022-12-06 2025-08-08 诺维信公司 涉及蛋白质-脱酰胺酶的肉类类似物产品的生产方法
EP4629838A1 (en) 2022-12-08 2025-10-15 Novozymes A/S Polypeptide having lysozyme activity and polynucleotides encoding same
WO2024121357A1 (en) 2022-12-08 2024-06-13 Novozymes A/S Fiber-degrading enzymes for animal feed comprising an oil seed material
CN120265743A (zh) 2022-12-14 2025-07-04 诺维信公司 改善的脂肪酶(gcl1)变体
CN120322453A (zh) 2022-12-14 2025-07-15 诺维信公司 高强度液体蛋白酶配制品
EP4634389A1 (en) 2022-12-16 2025-10-22 Boehringer Ingelheim RCV GmbH & Co KG Means and methods for increased protein expression by use of a combination of transport proteins and either chaperones or transcription factors
KR20250124113A (ko) 2022-12-16 2025-08-19 바스프 에스이 신규한 에틸렌디아민-n,n'-디숙신산 (edds) 신타아제
EP4638724A1 (en) 2022-12-19 2025-10-29 Novozymes A/S Carbohydrate esterase family 1 (ce1) polypeptides having ferulic acid esterase and/or acetyl xylan esterase activity and polynucleotides encoding same
EP4638768A2 (en) 2022-12-19 2025-10-29 Novozymes A/S Processes for producing fermentation products using fiber-degrading enzymes with engineered yeast
EP4638725A1 (en) 2022-12-19 2025-10-29 Novozymes A/S Carbohydrate esterase family 3 (ce3) polypeptides having acetyl xylan esterase activity and polynucleotides encoding same
EP4389864A1 (en) 2022-12-20 2024-06-26 Basf Se Cutinases
EP4639551A1 (en) 2022-12-20 2025-10-29 Novozymes A/S A method for providing a candidate biological sequence and related electronic device
CN120476196A (zh) 2022-12-21 2025-08-12 诺维信公司 用于细胞分离的微生物蛋白酶
EP4389865A1 (en) 2022-12-21 2024-06-26 Novozymes A/S Recombinant protease for cell detachment
EP4638684A1 (en) 2022-12-21 2025-10-29 Novozymes A/S Recombinant protease for cell detachment
EP4389886A1 (en) 2022-12-22 2024-06-26 Novozymes A/S Lactase enzymes and method of producing a milk-based product
EP4655371A1 (en) 2023-01-23 2025-12-03 Novozymes A/S Cleaning compositions and uses thereof
CN120936382A (zh) 2023-02-16 2025-11-11 阿斯利康(瑞典)有限公司 采用治疗性结合分子治疗癌症的组合疗法
WO2024175631A1 (en) 2023-02-22 2024-08-29 Novozymes A/S Oral care composition comprising invertase
GB202303328D0 (en) 2023-03-07 2023-04-19 Imperial College Innovations Ltd Synthetic promoters
GB202304385D0 (en) 2023-03-24 2023-05-10 Prostate Cancer Res Combinatorial IL-15 therapy
GB202307439D0 (en) 2023-05-18 2023-07-05 Ipsen Biopharm Ltd Treatment of a headache disorder with botylinum neurotoxin a
WO2024258820A2 (en) 2023-06-13 2024-12-19 Novozymes A/S Processes for producing fermentation products using engineered yeast expressing a beta-xylosidase
WO2025002934A1 (en) 2023-06-28 2025-01-02 Novozymes A/S Detergent composition comprising lipases
WO2025008283A1 (en) 2023-07-05 2025-01-09 Novozymes A/S Foamable dairy products
AU2024290001A1 (en) 2023-07-05 2025-12-04 Novozymes A/S Methods for obtaining plant-based ready-to-drink coffee or tea beverages
EP4273249A3 (en) 2023-07-07 2024-05-22 Novozymes A/S Improved expression of recombinant proteins
CN121464215A (zh) 2023-07-10 2026-02-03 诺维信公司 人工信号肽
AU2024321426A1 (en) 2023-08-09 2026-01-29 Novozymes A/S Methods for obtaining a plant-based food ingredient
AU2024325961A1 (en) 2023-08-15 2026-01-29 Novozymes A/S Polypeptides having alkaline phosphatase activity for animal feed
WO2025046141A1 (en) 2023-09-01 2025-03-06 Novozymes A/S Stabilized liquid deamidase compositions
CN121666449A (zh) 2023-09-13 2026-03-13 诺维信公司 稳定的脱酰胺酶组合物
WO2025061262A1 (en) 2023-09-19 2025-03-27 Novozymes A/S Methods for evaluating protein substrate gelling by microbial transglutaminase
CN121925177A (zh) 2023-09-26 2026-04-24 诺维信公司 在获得具有改善的稳定性的种子基乳制品替代性饮料的工艺中使用蛋白质脱酰胺酶
CN121925476A (zh) 2023-09-29 2026-04-24 诺维信公司 基于液滴的筛选方法
WO2025088003A1 (en) 2023-10-24 2025-05-01 Novozymes A/S Use of xyloglucanase for replacement of optical brightener
WO2025093845A1 (en) 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of high dose chimeric botulinum toxin a for the treatment of upper facial lines
WO2025093844A1 (en) 2023-11-01 2025-05-08 Ipsen Biopharm Limited Use of chimeric botulinum toxin a for treating blepharospasm and hemifacial spasm
WO2025103765A1 (en) 2023-11-17 2025-05-22 Novozymes A/S Lytic polysaccharide monooxygenases and their use in detergent
WO2025111274A2 (en) 2023-11-20 2025-05-30 Novozymes A/S Epimerase variants and polynucleotides encoding same
AU2024391409A1 (en) 2023-11-30 2026-04-23 Novozymes A/S Oral care composition comprising peptidase or lactonase
GB202318884D0 (en) 2023-12-11 2024-01-24 Ipsen Biopharm Ltd Formulation
WO2025132872A1 (en) 2023-12-20 2025-06-26 Novozymes A/S Modified leguminous protein with improved colloidal stability
WO2025133162A1 (en) 2023-12-20 2025-06-26 Novozymes A/S Recombinant protein expression
WO2025132815A1 (en) 2023-12-20 2025-06-26 Novozymes A/S Novel cas nucleases and polynucleotides encoding the same
WO2025132905A1 (en) 2023-12-22 2025-06-26 Novozymes A/S Fermentation method
WO2025140303A1 (en) 2023-12-28 2025-07-03 Novozymes A/S Enzymatic treatment of a material comprising corn protein
GB202320108D0 (en) 2023-12-28 2024-02-14 Ipsen Biopharm Ltd Biosensor
WO2025168806A1 (en) 2024-02-08 2025-08-14 Novozymes A/S Polypeptides having carbonic anhydrase activity and polynucleotides encoding same
WO2025191164A2 (en) 2024-03-12 2025-09-18 Novozymes A/S Use of chymopapain in cell detachment
GB202404021D0 (en) 2024-03-20 2024-05-01 Ipsen Biopharm Ltd Cell-based neurotoxin assay
WO2025196175A1 (en) 2024-03-22 2025-09-25 Novozymes A/S Oral care compositions comprising dnases
WO2025217017A1 (en) 2024-04-08 2025-10-16 Novozymes A/S Compositions and methods for increasing phosphorous availability
WO2025226596A1 (en) 2024-04-24 2025-10-30 Novozymes A/S Methods for producing secreted polypeptides
WO2025229230A1 (en) 2024-05-03 2025-11-06 Novozymes A/S Combined carbon capture and soda ash process
WO2025233391A1 (en) 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
WO2025233389A1 (en) 2024-05-09 2025-11-13 Novozymes A/S Stabilized liquid deamidase compositions
EP4650443A1 (en) 2024-05-13 2025-11-19 Novozymes A/S Stabilized liquid deamidase compositions
WO2025242320A1 (en) 2024-05-21 2025-11-27 Novozymes A/S Stabilized ready-to-drink coffee beverages
WO2025247765A1 (en) 2024-05-30 2025-12-04 Chr. Hansen A/S Non-heated fermented meat analogue product prepared with vegetable protein transglutaminase and pediococcus strains
WO2025257254A1 (en) 2024-06-12 2025-12-18 Novozymes A/S Lipases and lipase variants and the use thereof
WO2026017381A1 (en) 2024-07-17 2026-01-22 Novozymes A/S Optimized bacillus host cells
WO2024254620A2 (en) 2024-08-01 2024-12-12 Novozymes A/S Protease for diagnostics
WO2026057740A1 (en) 2024-09-12 2026-03-19 Astrazeneca Ab Treatment of cancer with therapeutic binding molecules
WO2026062399A1 (en) 2024-09-19 2026-03-26 Lift Biosciences Ltd Granulocytes and granulocyte precursors
WO2026068782A1 (en) 2024-09-30 2026-04-02 Novozymes A/S Protease variants and polynucleotides encoding same
WO2026076952A1 (en) 2024-10-08 2026-04-16 Novozymes A/S Processes for obtaining dairy protein-based ready-to-drink beverages

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE114723T1 (de) * 1987-03-02 1994-12-15 Enzon Lab Inc Organismus als träger für ''single chain antibody domain (scad)''.
ATE243754T1 (de) * 1987-05-21 2003-07-15 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung
WO1989001526A1 (en) * 1987-08-07 1989-02-23 Genelabs Incorporated Coincidence cloning method and library
CA2016841C (en) * 1989-05-16 1999-09-21 William D. Huse A method for producing polymers having a preselected activity
AU652539B2 (en) * 1989-05-16 1994-09-01 Medical Research Council Co-expression of heteromeric receptors
CA2016842A1 (en) * 1989-05-16 1990-11-16 Richard A. Lerner Method for tapping the immunological repertoire

Also Published As

Publication number Publication date
IE63054B1 (en) 1995-03-22
EP0550645A4 (en) 1993-09-01
JPH06505145A (ja) 1994-06-16
TW314553B (da) 1997-09-01
JP3373510B2 (ja) 2003-02-04
DE69132700T2 (de) 2001-12-06
ATE204607T1 (de) 2001-09-15
NZ239988A (en) 1995-06-27
IE913425A1 (en) 1992-04-08
AU667291B2 (en) 1996-03-21
EP0550645B1 (en) 2001-08-22
WO1992006204A1 (en) 1992-04-16
AU8731891A (en) 1992-04-28
EP0550645A1 (en) 1993-07-14
DE69132700D1 (de) 2001-09-27
CA2092802A1 (en) 1992-03-29

Similar Documents

Publication Publication Date Title
IL99552A0 (en) Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DK217683A (da) Pyrrolo-(3,4-c)-pyrroler samt deres fremstilling og anvendelse som pigmenter
DE68911033D1 (de) Alkoxy-1,2,4-triazolo (1,5-c) pyrimidine-2-sulfonamide, Verfahren zu ihrer Herstellung und Zwischenprodukte.
DE3884626D1 (de) Polyurethanpulver-beschichtungszusammensetzung.
AU1642192A (en) Non-azeotropic refrigerant compositions comprising difluoromethane; 1,1,1-trifluoroethane; or propane
DE3852571D1 (de) Reinigungsmittelzusammensetzung für harte Oberflächen.
IL52549A (en) 1-phenoxy-1-imidazolo(or 1,2,4-triazolo)-4-halo-butan-2-ones(oles),process for their preparation and fungicidal compositions containing them
BR8900382A (pt) Composicao cremosa para desengorduramento,contendo abrasivo
DE69004798D1 (de) Handgriff für skistock.
IL85840A (en) Substituted 2-phenylimidazo(1,2-a)pyridine-3-acetamides and pharmaceutical compositions containing them
EP0426974A3 (en) Composition containing acetaminophen
ZA892869B (en) 5-fluoromethyl-1,2,4-triazolo(1,5-a)-pyrimidine-2-sulfonamides,process for their preparation and composition for their use as herbicides
DE69017368D1 (de) Aromatische Polysulfon-Harzzusammensetzung.
DE69013015D1 (de) Protein aus dem Cytosol, das FK-506 binden kann.
EP0413352A3 (en) Solvent based coating composition
DE69110220D1 (de) Harzmischung zum Beschichten und Elektroabscheidungsbeschichtungszusammensetzung, welche diese enthält.
DE69019186D1 (de) N-substituierte-3-(Stickstoff-enthaltende 5-Ring)-Benzensulfonamid-Derivate, Verfahren zu ihrer Herstellung und Herbizid-Zusammensetzungen.
IL90004A (en) 5-fluoromethyl-1,2,4-triazolo (1,5-a)-pyrinidine-2- sulfonamides, process for their preparation and compositions for their use as herbicides
GB8911669D0 (en) Chemically-curing,two-part polyurethane composition
IL88136A0 (en) Compounds containing triazole groups,use thereof as fungicides and preparative processes
ZA79615B (en) 1,1-disubstituted octahydro-indolo(2,3-a)quinolizines,process for the preparation thereof and composition containing same
GB2225944B (en) Stable biocide composition for industrial use
SE9002213D0 (sv) Albumin binding proteins
NZ235526A (en) Lepidopteran allatostatin-like polypeptides; dna encoding them; baculovirus containing the dna; and insecticidal compositions containing the virus
SU834585A1 (ru) Цифровой анализатор