HUP9903971A1 - Izoflavonok alkalmazása klimax elleni gyógyszerkészítmények előállítására - Google Patents

Izoflavonok alkalmazása klimax elleni gyógyszerkészítmények előállítására

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Publication number
HUP9903971A1
HUP9903971A1 HU9903971A HUP9903971A HUP9903971A1 HU P9903971 A1 HUP9903971 A1 HU P9903971A1 HU 9903971 A HU9903971 A HU 9903971A HU P9903971 A HUP9903971 A HU P9903971A HU P9903971 A1 HUP9903971 A1 HU P9903971A1
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HU
Hungary
Prior art keywords
group
hydrogen atom
same
defined above
alkyl
Prior art date
Application number
HU9903971A
Other languages
English (en)
Inventor
George Eustace Joannou
Graham Edmund Kelly
Original Assignee
Novogen Research Pty.Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Novogen Research Pty.Ltd. filed Critical Novogen Research Pty.Ltd.
Publication of HUP9903971A1 publication Critical patent/HUP9903971A1/hu
Publication of HUP9903971A3 publication Critical patent/HUP9903971A3/hu

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    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
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Abstract

A találmány tárgyát (I) általános képlettel leírható izoflavonvegyületek, - amely képletben Z jelentése hidrogénatom, R1 jelentésehidrogénatom, vagy RACO csoport, ahol RA jelentése 1-10 szénatomszámúalkilcsoport vagy aminosav csoport, R2 jelentése hidrogénatom, OHcsoport vagy ORB csoport, ahol RB jelentése aminosav csoport vagy CORAcsoport, ahol RA jelentése azonos a fentiekben definiáltakkal, Wjelentése hidrogénatom, A jelentése hidrogénatom vagy OH csoport,valamint B az (a), (b) és (c) csoportok közül kerül kiválasztásra;vagy W jelentése hidrogénatom, valamint A és B együttesen egy hattagból álló gyűrűs csoportot képez; vagy W, A és B a hozzájukkapcsolódó csoportokkal együtt egy heteroaromás csoportot; vagy W és Aa hozzájuk kapcsolódó csoportokkal együtt egy heteroaromás csoportotalkot; R3 jelentése hidrogénatom, CORA csoport, ahol RA jelentéseazonos a fentiekben definiáltakkal, CO2RC csoport, ahol RC jelentése1-10 szénatomszámú alkilcsoport vagy CORB csoport, ahol RB jelentéseazonos a fentiekben definiáltakkal, R4 jelentése hidrogénatom, CORDcsoport, ahol RD jelentése hidrogénatom, OH csoport, 1-10szénatomszámú alkilcsoport vagy aminosav csoport, CO2RC csoport, aholRC jelentése azonos a fentiekben definiáltakkal, CORE csoport, ahol REjelentése hidrogénatom, 1-10 szénatomszámú alkilcsoport vagy aminosavcsoport, COOH csoport, CORC csoport, ahol RC jelentése azonos afentiekben definiáltakkal vagy CONHRE csoport, ahol RE jelentéseazonos a fentiekben definiáltakkal, R5 jelentése hidrogénatom, CO2RCcsoport, ahol RC jelentése azonos a fentiekben definiáltakkal vagyCORCORE csoport, ahol RC és RE jelentése azonos a fentiekbendefiniáltakkal és ahol a két R5 csoport - legyen ugyanaz vagykülönböző - ugyanahhoz a csoporthoz kapcsolódik, R6 jelentésehidrogénatom vagy hidroxi-(1-10 szénatomszámú alkil)csoport, Xjelentése előnyösen oxigénatom, de lehet nitrogénatom vagy kénatom is,valamint Y jelentése egy -OR7 csoporttal szubsztituált fenil-csoport,ahol az R7 jelentése hidrogénatom vagy alkilcsoport; alkalmazása aklimax tünetegyüttese elleni gyógyszerkészítmények előállítására,valamint ezeket a vegyületeket tartalmazó gyógyszerkészítményekképezik. Ó
HU9903971A 1996-08-30 1997-08-29 Use of isoflavones for producing pharmaceutical compositions against menopausal syndrome HUP9903971A3 (en)

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AUPO2039A AUPO203996A0 (en) 1996-08-30 1996-08-30 Therapeutic uses
PCT/AU1997/000563 WO1998008503A1 (en) 1996-08-30 1997-08-29 Therapeutic methods and compositions involving isoflavones

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HU (1) HUP9903971A3 (hu)
IL (3) IL128765A0 (hu)
NO (3) NO325681B1 (hu)
NZ (2) NZ334025A (hu)
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