EP1368024A4 - TREATMENT OF RESTENOSIS - Google Patents

TREATMENT OF RESTENOSIS

Info

Publication number
EP1368024A4
EP1368024A4 EP02707999A EP02707999A EP1368024A4 EP 1368024 A4 EP1368024 A4 EP 1368024A4 EP 02707999 A EP02707999 A EP 02707999A EP 02707999 A EP02707999 A EP 02707999A EP 1368024 A4 EP1368024 A4 EP 1368024A4
Authority
EP
European Patent Office
Prior art keywords
restenosis
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP02707999A
Other languages
German (de)
French (fr)
Other versions
EP1368024A1 (en
Inventor
Alan Husband
Graham Edmund Kelly
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Marshall Edwards Inc
Original Assignee
Novogen Research Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPR3770A external-priority patent/AUPR377001A0/en
Priority claimed from AUPR5926A external-priority patent/AUPR592601A0/en
Application filed by Novogen Research Pty Ltd filed Critical Novogen Research Pty Ltd
Publication of EP1368024A1 publication Critical patent/EP1368024A1/en
Publication of EP1368024A4 publication Critical patent/EP1368024A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
EP02707999A 2001-03-16 2002-03-15 TREATMENT OF RESTENOSIS Withdrawn EP1368024A4 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AUPR3770A AUPR377001A0 (en) 2001-03-16 2001-03-16 Treatment of restenosis
AUPR377001 2001-03-16
AUPR5926A AUPR592601A0 (en) 2001-06-26 2001-06-26 Treatment of restenosis
AUPR592601 2001-06-26
PCT/AU2002/000288 WO2002074307A1 (en) 2001-03-16 2002-03-15 Treatment of restenosis

Publications (2)

Publication Number Publication Date
EP1368024A1 EP1368024A1 (en) 2003-12-10
EP1368024A4 true EP1368024A4 (en) 2009-03-18

Family

ID=25646619

Family Applications (1)

Application Number Title Priority Date Filing Date
EP02707999A Withdrawn EP1368024A4 (en) 2001-03-16 2002-03-15 TREATMENT OF RESTENOSIS

Country Status (3)

Country Link
EP (1) EP1368024A4 (en)
JP (2) JP4256679B2 (en)
WO (1) WO2002074307A1 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR363301A0 (en) 2001-03-08 2001-04-05 Novogen Research Pty Ltd Dimeric isoflavones
US7338971B2 (en) * 2001-08-30 2008-03-04 El-Naggar Mawaheb M Treatment of inflammatory, cancer, and thrombosis disorders
AUPR846401A0 (en) * 2001-10-25 2001-11-15 Novogen Research Pty Ltd 6-Hydroxy isoflavones, derivatives and medicaments involving same
JP2005528391A (en) * 2002-04-09 2005-09-22 ノボゲン リサーチ ピーティーワイ リミテッド Therapeutic methods and compositions comprising isoflav-3-ene and isoflavan structures
ES2360130T3 (en) * 2005-03-24 2011-06-01 Novogen Research Pty. Ltd. DIMMERS OF ISOFLAVONOIDS.
US20100068238A1 (en) * 2005-07-15 2010-03-18 Nandkishore Managoli Implantable Medical Devices Comprising a Flavonoid or Derivative Thereof for Prevention of Restenosis
EP2314295B1 (en) * 2005-07-29 2015-01-28 Resverlogix, Inc Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
AU2007345526B2 (en) 2007-02-01 2013-02-28 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular diseases
TWI366565B (en) 2007-06-06 2012-06-21 Otsuka Pharma Co Ltd Quinolone compound and pharmaceutical composition
US8114995B2 (en) 2008-06-26 2012-02-14 Resverlogix Corp. Methods of preparing quinazolinone derivatives
EP2362773A4 (en) * 2008-10-22 2012-05-09 Novogen Res Pty Ltd METHODS OF CAUSING PROGRAMMED CELL DEATH
TWI492943B (en) 2008-12-05 2015-07-21 大塚製藥股份有限公司 Quinolone compound and pharmaceutical composition
WO2010079431A2 (en) 2009-01-08 2010-07-15 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
AU2010224523B2 (en) 2009-03-18 2014-05-08 Resverlogix Corp. Novel anti-inflammatory agents
EP2421533B1 (en) 2009-04-22 2018-10-17 Resverlogix Corp. Novel anti-inflammatory agents
PT2773354T (en) 2011-11-01 2019-07-17 Resverlogix Corp Oral immediate release formulations for substituted quinazolinones
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
CA2895905A1 (en) 2012-12-21 2014-06-26 Zenith Epigenetics Corp. Novel heterocyclic compounds as bromodomain inhibitors
ES2643407T3 (en) 2014-02-07 2017-11-22 Novogen Ltd. Functionalized benzopyran compounds and their use
WO2016147053A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
KR102005237B1 (en) * 2017-02-28 2019-07-30 서울대학교산학협력단 Recombinant e.coli producing equol derivatives and method for producing equol derivatives using thereof
MY208662A (en) 2018-04-18 2025-05-22 Constellation Pharmaceuticals Inc Modulators of methyl modifying enzymes, compositions and uses thereof
CN120097995A (en) 2018-05-21 2025-06-06 星座制药公司 Regulators of methyl modification enzymes, compositions and uses thereof
WO2021016414A1 (en) 2019-07-24 2021-01-28 Constellation Pharmaceuticals, Inc. Crystalline forms of 7-chloro-2-(4-(3-methoxyazetidin-1-yl)cyclohexyl)-2,4-dimethyl-n-((6-methyl-4-(methylthio)-2-oxo-1,2-dihydropyridin-3-yl)methyl)benzo[d][1,3]dioxole-5-carboxamide

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2190411A1 (en) * 1972-06-27 1974-02-01 Blaise Rolland Derivs of 7-hydroxy isoflavones - vascular protectors, antiphlogistics and anti-allergics, prepd from a halocarboxylic acid and a 7-hydroxy isoflavone
WO1996031206A2 (en) * 1995-04-07 1996-10-10 Warner-Lambert Company Flavones and coumarins as agents for the treatment of atherosclerosis
US5855892A (en) * 1997-09-19 1999-01-05 Potter; Susan M. Method for decreasing LDL-cholesterol concentration and increasing HDL-cholesterol concentration in the blood to reduce the risk of atherosclerosis and vascular disease
WO2000030665A1 (en) * 1998-11-25 2000-06-02 Nutri Pharma Asa Composition comprising soy protein, dietary fibres and a phytoestrogen compound and use thereof in the prevention and/or treatment of cardiovascular diseases
WO2001017986A1 (en) * 1999-09-06 2001-03-15 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPO203996A0 (en) * 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
AU5440799A (en) * 1998-09-17 2000-04-10 Guido Schnyder Method and drug for the treatment of coronary heart disease and for the prevention of restenosis after percutaneous transluminal coronary angioplasty
US6413546B1 (en) * 1999-03-18 2002-07-02 Indena, S.P.A. Tablets incorporating isoflavone plant extracts and methods of manufacturing them
AUPQ008399A0 (en) * 1999-04-28 1999-05-27 Novogen Research Pty Ltd Cariovascular applications
AUPQ008299A0 (en) * 1999-04-30 1999-05-27 G.J. Consultants Pty Ltd Isoflavone metabolites

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2190411A1 (en) * 1972-06-27 1974-02-01 Blaise Rolland Derivs of 7-hydroxy isoflavones - vascular protectors, antiphlogistics and anti-allergics, prepd from a halocarboxylic acid and a 7-hydroxy isoflavone
WO1996031206A2 (en) * 1995-04-07 1996-10-10 Warner-Lambert Company Flavones and coumarins as agents for the treatment of atherosclerosis
US5855892A (en) * 1997-09-19 1999-01-05 Potter; Susan M. Method for decreasing LDL-cholesterol concentration and increasing HDL-cholesterol concentration in the blood to reduce the risk of atherosclerosis and vascular disease
WO2000030665A1 (en) * 1998-11-25 2000-06-02 Nutri Pharma Asa Composition comprising soy protein, dietary fibres and a phytoestrogen compound and use thereof in the prevention and/or treatment of cardiovascular diseases
WO2001017986A1 (en) * 1999-09-06 2001-03-15 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HUANG HUEI-CHEN ET AL: "Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell", EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER BV, NL, vol. 251, no. 1, 1 January 1994 (1994-01-01), pages 91 - 93, XP002349489, ISSN: 0014-2999 *
See also references of WO02074307A1 *
TRAXLER P ET AL: "STRATEGIES TOWARD THE DESIGN OF NOVEL AND SELECTIVE PROTEIN TYROSINE KINASE INHIBITORS", PHARMACOLOGY AND THERAPEUTICS, ELSEVIER, GB, vol. 82, no. 2/03, 10 June 1999 (1999-06-10), pages 195 - 206, XP000985237, ISSN: 0163-7258 *
TRIEU V N ET AL: "EGF-GENISTEIN INHIBITS NEOINTIMAL HYPERPLASIA AFTER VASCULAR INJURY IN A EXPERIMENTAL RESTENOSIS MODEL", JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, NEW YORK, NY, vol. 35, no. 4, 1 April 2000 (2000-04-01), pages 595 - 605, XP001011807, ISSN: 0160-2446 *

Also Published As

Publication number Publication date
JP2009143908A (en) 2009-07-02
WO2002074307A1 (en) 2002-09-26
JP2004529907A (en) 2004-09-30
EP1368024A1 (en) 2003-12-10
JP4256679B2 (en) 2009-04-22

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 20030911

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Effective date: 20090213

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Effective date: 20091120

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Owner name: MARSHALL EDWARDS, INC.

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Effective date: 20120308