EP1368024A4 - Behandlung von restenose - Google Patents
Behandlung von restenoseInfo
- Publication number
- EP1368024A4 EP1368024A4 EP02707999A EP02707999A EP1368024A4 EP 1368024 A4 EP1368024 A4 EP 1368024A4 EP 02707999 A EP02707999 A EP 02707999A EP 02707999 A EP02707999 A EP 02707999A EP 1368024 A4 EP1368024 A4 EP 1368024A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- restenosis
- treatment
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Epidemiology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyrane Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPR3770A AUPR377001A0 (en) | 2001-03-16 | 2001-03-16 | Treatment of restenosis |
AUPR377001 | 2001-03-16 | ||
AUPR5926A AUPR592601A0 (en) | 2001-06-26 | 2001-06-26 | Treatment of restenosis |
AUPR592601 | 2001-06-26 | ||
PCT/AU2002/000288 WO2002074307A1 (en) | 2001-03-16 | 2002-03-15 | Treatment of restenosis |
Publications (2)
Publication Number | Publication Date |
---|---|
EP1368024A1 EP1368024A1 (de) | 2003-12-10 |
EP1368024A4 true EP1368024A4 (de) | 2009-03-18 |
Family
ID=25646619
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP02707999A Withdrawn EP1368024A4 (de) | 2001-03-16 | 2002-03-15 | Behandlung von restenose |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1368024A4 (de) |
JP (2) | JP4256679B2 (de) |
WO (1) | WO2002074307A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7338971B2 (en) * | 2001-08-30 | 2008-03-04 | El-Naggar Mawaheb M | Treatment of inflammatory, cancer, and thrombosis disorders |
AUPR846401A0 (en) * | 2001-10-25 | 2001-11-15 | Novogen Research Pty Ltd | 6-Hydroxy isoflavones, derivatives and medicaments involving same |
WO2003086386A1 (en) * | 2002-04-09 | 2003-10-23 | Novogen Research Pty Ltd | Therapeutic methods and compositions involving isoflav-3-ene and isoflavan structures |
NZ561574A (en) * | 2005-03-24 | 2010-03-26 | Novogen Res Pty Ltd | Anti-inflammatory modalities for use against pain, oedema, and erythema (benzotetrahydropyrans, benzopyran derivatives, isoflavonoid derivatives) |
GB2443576A (en) * | 2005-07-15 | 2008-05-07 | Sahajanand Biotech Private Ltd | Implantable medical devices comprising a flavonoid or derivative thereof for prevention of restenosis |
WO2007016525A2 (en) * | 2005-07-29 | 2007-02-08 | Resverlogix Corp. | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
ES2454966T3 (es) | 2007-02-01 | 2014-04-14 | Resverlogix Corp. | Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares |
TWI366565B (en) | 2007-06-06 | 2012-06-21 | Otsuka Pharma Co Ltd | Quinolone compound and pharmaceutical composition |
US8114995B2 (en) | 2008-06-26 | 2012-02-14 | Resverlogix Corp. | Methods of preparing quinazolinone derivatives |
WO2010045674A1 (en) * | 2008-10-22 | 2010-04-29 | Novogen Research Pty Ltd | Methods for inducing programmed cell death |
TWI472525B (zh) | 2008-12-05 | 2015-02-11 | Otsuka Pharma Co Ltd | 喹啉酮化合物及藥學組成物 |
ES2542835T3 (es) | 2009-01-08 | 2015-08-12 | Resverlogix Corporation | Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares |
CA3146333A1 (en) | 2009-03-18 | 2010-09-23 | Resverlogix Corp. | Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents |
ES2821018T3 (es) | 2009-04-22 | 2021-04-23 | Resverlogix Corp | Nuevos agentes antiinflamatorios |
RS58911B1 (sr) | 2011-11-01 | 2019-08-30 | Resverlogix Corp | Oralne formulacije sa trenutnim otpuštanjem za supstituisane hinazolinone |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
US9073878B2 (en) | 2012-11-21 | 2015-07-07 | Zenith Epigenetics Corp. | Cyclic amines as bromodomain inhibitors |
US9271978B2 (en) | 2012-12-21 | 2016-03-01 | Zenith Epigenetics Corp. | Heterocyclic compounds as bromodomain inhibitors |
NZ711603A (en) | 2014-02-07 | 2017-05-26 | Novogen ltd | Functionalised benzopyran compounds and use thereof |
CA2977308A1 (en) | 2015-03-13 | 2016-09-22 | Resverlogix Corp. | Compositions and therapeutic methods for the treatment of complement-associated diseases |
KR102005237B1 (ko) * | 2017-02-28 | 2019-07-30 | 서울대학교산학협력단 | 에쿠올 유도체를 생산하는 재조합 대장균 및 이를 이용한 에쿠올 유도체 합성 방법 |
SG11202009438UA (en) | 2018-04-18 | 2020-11-27 | Constellation Pharmaceuticals Inc | Modulators of methyl modifying enzymes, compositions and uses thereof |
EP3797108B1 (de) | 2018-05-21 | 2022-07-20 | Constellation Pharmaceuticals, Inc. | Modulatoren von methyl modifizierenden enzyme, zusammensetzungen und ihre verwendung |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2190411A1 (en) * | 1972-06-27 | 1974-02-01 | Blaise Rolland | Derivs of 7-hydroxy isoflavones - vascular protectors, antiphlogistics and anti-allergics, prepd from a halocarboxylic acid and a 7-hydroxy isoflavone |
WO1996031206A2 (en) * | 1995-04-07 | 1996-10-10 | Warner-Lambert Company | Flavones and coumarins as agents for the treatment of atherosclerosis |
US5855892A (en) * | 1997-09-19 | 1999-01-05 | Potter; Susan M. | Method for decreasing LDL-cholesterol concentration and increasing HDL-cholesterol concentration in the blood to reduce the risk of atherosclerosis and vascular disease |
WO2000030665A1 (en) * | 1998-11-25 | 2000-06-02 | Nutri Pharma Asa | Composition comprising soy protein, dietary fibres and a phytoestrogen compound and use thereof in the prevention and/or treatment of cardiovascular diseases |
WO2001017986A1 (en) * | 1999-09-06 | 2001-03-15 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AUPO203996A0 (en) * | 1996-08-30 | 1996-09-26 | Novogen Research Pty Ltd | Therapeutic uses |
WO2000016759A2 (en) * | 1998-09-17 | 2000-03-30 | Guido Schnyder | Genistein for the treatment of coronary heart disease and for the prevention of restenosis after percutaneous transluminal coronary angioplasty |
US6413546B1 (en) * | 1999-03-18 | 2002-07-02 | Indena, S.P.A. | Tablets incorporating isoflavone plant extracts and methods of manufacturing them |
AUPQ008399A0 (en) * | 1999-04-28 | 1999-05-27 | Novogen Research Pty Ltd | Cariovascular applications |
AUPQ008299A0 (en) * | 1999-04-30 | 1999-05-27 | G.J. Consultants Pty Ltd | Isoflavone metabolites |
-
2002
- 2002-03-15 EP EP02707999A patent/EP1368024A4/de not_active Withdrawn
- 2002-03-15 JP JP2002573014A patent/JP4256679B2/ja not_active Expired - Fee Related
- 2002-03-15 WO PCT/AU2002/000288 patent/WO2002074307A1/en active Application Filing
-
2008
- 2008-12-05 JP JP2008311048A patent/JP2009143908A/ja active Pending
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2190411A1 (en) * | 1972-06-27 | 1974-02-01 | Blaise Rolland | Derivs of 7-hydroxy isoflavones - vascular protectors, antiphlogistics and anti-allergics, prepd from a halocarboxylic acid and a 7-hydroxy isoflavone |
WO1996031206A2 (en) * | 1995-04-07 | 1996-10-10 | Warner-Lambert Company | Flavones and coumarins as agents for the treatment of atherosclerosis |
US5855892A (en) * | 1997-09-19 | 1999-01-05 | Potter; Susan M. | Method for decreasing LDL-cholesterol concentration and increasing HDL-cholesterol concentration in the blood to reduce the risk of atherosclerosis and vascular disease |
WO2000030665A1 (en) * | 1998-11-25 | 2000-06-02 | Nutri Pharma Asa | Composition comprising soy protein, dietary fibres and a phytoestrogen compound and use thereof in the prevention and/or treatment of cardiovascular diseases |
WO2001017986A1 (en) * | 1999-09-06 | 2001-03-15 | Novogen Research Pty Ltd | Compositions and therapeutic methods involving isoflavones and analogues thereof |
Non-Patent Citations (4)
Title |
---|
HUANG HUEI-CHEN ET AL: "Antiproliferative effect of baicalein, a flavonoid from a Chinese herb, on vascular smooth muscle cell", EUROPEAN JOURNAL OF PHARMACOLOGY, ELSEVIER BV, NL, vol. 251, no. 1, 1 January 1994 (1994-01-01), pages 91 - 93, XP002349489, ISSN: 0014-2999 * |
See also references of WO02074307A1 * |
TRAXLER P ET AL: "STRATEGIES TOWARD THE DESIGN OF NOVEL AND SELECTIVE PROTEIN TYROSINE KINASE INHIBITORS", PHARMACOLOGY AND THERAPEUTICS, ELSEVIER, GB, vol. 82, no. 2/03, 10 June 1999 (1999-06-10), pages 195 - 206, XP000985237, ISSN: 0163-7258 * |
TRIEU V N ET AL: "EGF-GENISTEIN INHIBITS NEOINTIMAL HYPERPLASIA AFTER VASCULAR INJURY IN A EXPERIMENTAL RESTENOSIS MODEL", JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, NEW YORK, NY, vol. 35, no. 4, 1 April 2000 (2000-04-01), pages 595 - 605, XP001011807, ISSN: 0160-2446 * |
Also Published As
Publication number | Publication date |
---|---|
EP1368024A1 (de) | 2003-12-10 |
JP2009143908A (ja) | 2009-07-02 |
WO2002074307A1 (en) | 2002-09-26 |
JP2004529907A (ja) | 2004-09-30 |
JP4256679B2 (ja) | 2009-04-22 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
|
17P | Request for examination filed |
Effective date: 20030911 |
|
AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LI LU MC NL PT SE TR |
|
AX | Request for extension of the european patent |
Extension state: AL LT LV MK RO SI |
|
A4 | Supplementary search report drawn up and despatched |
Effective date: 20090213 |
|
17Q | First examination report despatched |
Effective date: 20091120 |
|
RAP1 | Party data changed (applicant data changed or rights of an application transferred) |
Owner name: MARSHALL EDWARDS, INC. |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
|
18D | Application deemed to be withdrawn |
Effective date: 20120308 |