ATE101143T1 - Verbessertes verfahren zur darstellung substituierter isoflavonderivate. - Google Patents

Verbessertes verfahren zur darstellung substituierter isoflavonderivate.

Info

Publication number
ATE101143T1
ATE101143T1 AT90906260T AT90906260T ATE101143T1 AT E101143 T1 ATE101143 T1 AT E101143T1 AT 90906260 T AT90906260 T AT 90906260T AT 90906260 T AT90906260 T AT 90906260T AT E101143 T1 ATE101143 T1 AT E101143T1
Authority
AT
Austria
Prior art keywords
pct
improved method
isoflavone derivatives
preparing substituted
sec
Prior art date
Application number
AT90906260T
Other languages
English (en)
Inventor
Tamas Kallay
Gyoergy Lanyi
Laszlo Ledniczky
Lajos Imrei
Gyoergy Hoffmann
Maria Sziladi
Eva Somfai
Tibor Montay
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Application granted granted Critical
Publication of ATE101143T1 publication Critical patent/ATE101143T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT90906260T 1990-04-06 1990-04-06 Verbessertes verfahren zur darstellung substituierter isoflavonderivate. ATE101143T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/HU1990/000023 WO1991015483A1 (en) 1990-04-06 1990-04-06 An improved process for the preparation of substituted isoflavone derivatives

Publications (1)

Publication Number Publication Date
ATE101143T1 true ATE101143T1 (de) 1994-02-15

Family

ID=10980899

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90906260T ATE101143T1 (de) 1990-04-06 1990-04-06 Verbessertes verfahren zur darstellung substituierter isoflavonderivate.

Country Status (15)

Country Link
US (1) US5247102A (de)
EP (1) EP0478558B1 (de)
JP (1) JPH089610B2 (de)
KR (1) KR0149172B1 (de)
AT (1) ATE101143T1 (de)
AU (1) AU631860B2 (de)
CA (1) CA2058619C (de)
DE (1) DE69006502T2 (de)
DK (1) DK0478558T3 (de)
FI (1) FI915741A0 (de)
HK (1) HK1003995A1 (de)
LT (1) LT3463B (de)
NO (1) NO300733B1 (de)
RU (1) RU2036918C1 (de)
WO (1) WO1991015483A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002603A (en) * 1989-12-04 1991-03-26 Board Of Trustees Operating Michigan State University Method and compositions for stimulating vesicular-arbuscular mycorrhizal fungi
US5204369A (en) * 1991-07-01 1993-04-20 The Endowment For Research In Human Biology Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse
FR2689127B1 (fr) * 1992-03-31 1994-05-06 Adir Cie Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant.
EP0656786B2 (de) 1992-05-19 2014-04-23 Novogen Research Pty Ltd Verwendung von isoflavon phyto-östrogen extrakten von soja oder klee
HUT68558A (en) * 1993-07-20 1995-06-28 Chinoin Gyogyszer Es Vegyeszet Method for preparing isoflavon derivatives
US5670632A (en) * 1996-01-18 1997-09-23 Acds Technologies, Ltd. Process for obtaining an isoflavone concentrate from a soybean extract
AUPO203996A0 (en) * 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
US6146668A (en) 1997-04-28 2000-11-14 Novogen, Inc. Preparation of isoflavones from legumes
US6255497B1 (en) 1997-04-29 2001-07-03 The Endowment For Research In Human Biology, Inc. Method for the inhibition of ALDH-I useful in the treatment of alcohol dependence or alcohol abuse
EP0979074A4 (de) * 1997-05-01 2003-07-09 Novogen Inc Behandlung oder vorbeugung klimakteriumsymptomen und der osteoporose
AUPP112497A0 (en) * 1997-12-24 1998-01-22 Novogen Research Pty Ltd Compositions and method for protecting skin from UV induced immunosupression and skin damage
IT1298619B1 (it) * 1998-03-10 2000-01-12 Erregierre Spa Processo di preparazione dell'epriflavone
AUPP260798A0 (en) * 1998-03-26 1998-04-23 Novogen Research Pty Ltd Treatment of medical related conditions with isoflavone containing extracts of clover
AUPQ266199A0 (en) * 1999-09-06 1999-09-30 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
US20090233999A1 (en) * 1999-09-06 2009-09-17 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
AUPQ520300A0 (en) * 2000-01-21 2000-02-17 Novogen Research Pty Ltd Food product and process
AUPR363301A0 (en) * 2001-03-08 2001-04-05 Novogen Research Pty Ltd Dimeric isoflavones
US20050119301A1 (en) * 2001-03-16 2005-06-02 Alan Husband Treatment of restenosis
US6818668B2 (en) 2002-04-12 2004-11-16 Biotest Laboratories, Llc 5-alkyl-7-alkylcarbonate-isoflavone ester and related method
CA2491089A1 (en) 2002-06-27 2004-01-08 The Endowment For Research In Human Biology, Inc. Compounds useful for the inhibition of aldh
AU2003255232A1 (en) 2002-08-07 2004-02-25 University Of Mississippi Antigiardial agents and use thereof
US8158810B2 (en) 2006-07-27 2012-04-17 Gilead Sciences, Inc. ALDH-2 inhibitors in the treatment of addiction
TWI324514B (en) 2008-02-26 2010-05-11 Univ Kaohsiung Medical Isoflavone derivatives and pharmaceutical compositions comprising the same
TWI365071B (en) 2008-02-26 2012-06-01 Univ Kaohsiung Medical Isoxazole derivatives and pharmaceutical compositions comprising the same
CN103145673B (zh) * 2011-12-06 2015-05-20 安徽贝克生物制药有限公司 黄豆苷元衍生物及其药学上可接受的盐

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA201219A (en) 1920-06-22 Hippolyte Louis Sizaire Maurice Lubricating vehicle spring
CA193010A (en) 1919-04-02 1919-09-30 Alvin A. Ritcheson Motor vehicle
HU162377B (de) * 1970-05-27 1973-02-28
GB1495305A (en) * 1975-09-12 1977-12-14 Pfizer Ltd 3-phenyl-4-oxo-4h-benzopyran derivatives
GB1495189A (en) * 1975-09-12 1977-12-14 Pfizer Ltd 4-oxo-4h-benzopyran derivatives and process for their preparation
JPS60132976A (ja) * 1983-12-21 1985-07-16 Takeda Chem Ind Ltd 新規３−フエニル−４ｈ−１−ベンゾピラン−４−オン誘導体
US4644012A (en) * 1983-12-21 1987-02-17 Takeda Chemical Industries, Ltd. Treatment for osteoporosis
US5002603A (en) * 1989-12-04 1991-03-26 Board Of Trustees Operating Michigan State University Method and compositions for stimulating vesicular-arbuscular mycorrhizal fungi

Also Published As

Publication number Publication date
KR920701192A (ko) 1992-08-11
DE69006502D1 (de) 1994-03-17
WO1991015483A1 (en) 1991-10-17
KR0149172B1 (ko) 1998-10-15
EP0478558A1 (de) 1992-04-08
CA2058619A1 (en) 1991-10-07
NO300733B1 (no) 1997-07-14
LT3463B (en) 1995-10-25
LTIP779A (en) 1995-01-31
HK1003995A1 (en) 1998-11-13
RU2036918C1 (ru) 1995-06-09
AU5427490A (en) 1991-10-30
EP0478558B1 (de) 1994-02-02
US5247102A (en) 1993-09-21
CA2058619C (en) 1999-05-04
AU631860B2 (en) 1992-12-10
DK0478558T3 (da) 1994-05-02
NO914786D0 (no) 1991-12-05
JPH089610B2 (ja) 1996-01-31
NO914786L (no) 1991-12-05
JPH04507085A (ja) 1992-12-10
DE69006502T2 (de) 1994-05-19
FI915741A0 (fi) 1991-12-05

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee