SE9001402D0 - Process for the preparation of quinazoline dervatives - Google Patents
Process for the preparation of quinazoline dervativesInfo
- Publication number
- SE9001402D0 SE9001402D0 SE9001402A SE9001402A SE9001402D0 SE 9001402 D0 SE9001402 D0 SE 9001402D0 SE 9001402 A SE9001402 A SE 9001402A SE 9001402 A SE9001402 A SE 9001402A SE 9001402 D0 SE9001402 D0 SE 9001402D0
- Authority
- SE
- Sweden
- Prior art keywords
- general formula
- lower alkyl
- preparation
- group
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU193089A HU203333B (en) | 1989-04-21 | 1989-04-21 | Process for producing n-cyano-carboxamidine derivatives |
| HU193189A HU203342B (en) | 1989-04-21 | 1989-04-21 | Process for producing quinazoline deivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE9001402D0 true SE9001402D0 (sv) | 1990-04-20 |
| SE9001402L SE9001402L (sv) | 1990-10-22 |
Family
ID=26317437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9001402A SE9001402L (sv) | 1989-04-21 | 1990-04-20 | Foerfarande foer framstaellning av kinazolinderivattives |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPH02292282A (sv) |
| KR (1) | KR900016194A (sv) |
| AT (1) | AT398075B (sv) |
| BG (1) | BG91821A (sv) |
| CA (2) | CA2028953A1 (sv) |
| CH (1) | CH681300A5 (sv) |
| DK (1) | DK99090A (sv) |
| ES (1) | ES2019826A6 (sv) |
| FI (1) | FI902002A0 (sv) |
| GB (1) | GB2231571B (sv) |
| GR (1) | GR900100294A (sv) |
| IT (1) | IT1241128B (sv) |
| PL (1) | PL162976B1 (sv) |
| RU (1) | RU1838309C (sv) |
| SE (1) | SE9001402L (sv) |
| YU (1) | YU70890A (sv) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2077252C (en) * | 1992-08-31 | 2001-04-10 | Khashayar Karimian | Methods of making ureas and guanidines, and intermediates therefor |
| ES2096518B1 (es) * | 1994-03-28 | 1997-12-01 | Grupo Farmaceutico Almirall S | Nuevas anilinas. |
| WO2008015525A2 (en) * | 2006-07-31 | 2008-02-07 | Orchid Chemicals & Pharmaceuticals Limited | An improved process for the preparation of alfuzosin hydrochloride |
| EP2152697A2 (en) | 2007-05-04 | 2010-02-17 | Actavis Group PTC EHF | Process for the preparation of alfuzosin and salts thereof |
| NZ582950A (en) | 2007-08-02 | 2011-06-30 | Cipla Ltd | Process for the preparation of alfuzosin hydrochloride |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4026894A (en) * | 1975-10-14 | 1977-05-31 | Abbott Laboratories | Antihypertensive agents |
| US4044135A (en) * | 1975-10-14 | 1977-08-23 | Abbott Laboratories | Antihypertensive agents |
| GB1591490A (en) * | 1977-08-04 | 1981-06-24 | Abbott Lab | 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate |
| US4138561A (en) * | 1977-09-30 | 1979-02-06 | Bristol-Myers Company | Cyanocarboxamidines and quinazoline process |
| FI57751C (fi) * | 1977-10-25 | 1980-10-10 | Fermion Oy | Foerfarande foer framstaellning av 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner med blodtryckssaenkande verkan |
| FI56836C (fi) * | 1977-10-25 | 1980-04-10 | Fermion Oy | 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner |
| FR2421888A1 (fr) * | 1978-02-06 | 1979-11-02 | Synthelabo | Amides d'alkylene-diamines et leur application en therapeutique |
| FI59800C (fi) * | 1979-01-10 | 1981-10-12 | Fermion Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(furo-2-yl)-piperazin-1-yl)-kinazolin |
| FI67699C (fi) * | 1979-01-31 | 1985-05-10 | Orion Yhtymae Oy | Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan |
| ATE32074T1 (de) * | 1983-11-22 | 1988-02-15 | Heumann Ludwig & Co Gmbh | Verfahren zur herstellung von 4-amino-6,7dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)chinazolin und dessen physiologisch annehmbarer salze. |
-
1990
- 1990-04-11 YU YU00708/90A patent/YU70890A/xx unknown
- 1990-04-19 GR GR900100294A patent/GR900100294A/el unknown
- 1990-04-20 GB GB9008941A patent/GB2231571B/en not_active Expired - Lifetime
- 1990-04-20 CA CA002028953A patent/CA2028953A1/en not_active Abandoned
- 1990-04-20 DK DK099090A patent/DK99090A/da not_active Application Discontinuation
- 1990-04-20 IT IT20092A patent/IT1241128B/it active IP Right Grant
- 1990-04-20 CA CA2015066A patent/CA2015066A1/xx active Pending
- 1990-04-20 AT AT0093190A patent/AT398075B/de not_active IP Right Cessation
- 1990-04-20 JP JP2103239A patent/JPH02292282A/ja active Pending
- 1990-04-20 FI FI902002A patent/FI902002A0/fi not_active IP Right Cessation
- 1990-04-20 BG BG091821A patent/BG91821A/bg unknown
- 1990-04-20 RU SU904743794A patent/RU1838309C/ru active
- 1990-04-20 ES ES9001130A patent/ES2019826A6/es not_active Expired - Lifetime
- 1990-04-20 KR KR1019900005608A patent/KR900016194A/ko not_active Application Discontinuation
- 1990-04-20 SE SE9001402A patent/SE9001402L/sv not_active Application Discontinuation
- 1990-04-20 CH CH1348/90A patent/CH681300A5/de not_active IP Right Cessation
- 1990-04-20 PL PL28486090A patent/PL162976B1/pl unknown
Also Published As
| Publication number | Publication date |
|---|---|
| PL284860A1 (en) | 1991-03-11 |
| GB2231571A (en) | 1990-11-21 |
| SE9001402L (sv) | 1990-10-22 |
| AT398075B (de) | 1994-09-26 |
| PL162976B1 (pl) | 1994-01-31 |
| GB2231571B (en) | 1992-09-16 |
| BG91821A (bg) | 1993-12-24 |
| JPH02292282A (ja) | 1990-12-03 |
| CA2028953A1 (en) | 1990-10-22 |
| RU1838309C (ru) | 1993-08-30 |
| KR900016194A (ko) | 1990-11-12 |
| ATA93190A (de) | 1994-01-15 |
| GR900100294A (el) | 1991-09-27 |
| FI902002A0 (fi) | 1990-04-20 |
| CH681300A5 (sv) | 1993-02-26 |
| DK99090D0 (da) | 1990-04-20 |
| DK99090A (da) | 1990-10-22 |
| YU70890A (en) | 1992-05-28 |
| IT9020092A0 (it) | 1990-04-20 |
| ES2019826A6 (es) | 1991-07-01 |
| CA2015066A1 (en) | 1990-10-21 |
| GB9008941D0 (en) | 1990-06-20 |
| IT1241128B (it) | 1993-12-29 |
| IT9020092A1 (it) | 1991-10-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NAV | Patent application has lapsed |
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