IT9020092A0 - Procedimento per la preparazione di derivati chinazolinici - Google Patents

Procedimento per la preparazione di derivati chinazolinici

Info

Publication number
IT9020092A0
IT9020092A0 IT9020092A IT2009290A IT9020092A0 IT 9020092 A0 IT9020092 A0 IT 9020092A0 IT 9020092 A IT9020092 A IT 9020092A IT 2009290 A IT2009290 A IT 2009290A IT 9020092 A0 IT9020092 A0 IT 9020092A0
Authority
IT
Italy
Prior art keywords
procedure
preparation
quinazoline derivatives
quinazoline
derivatives
Prior art date
Application number
IT9020092A
Other languages
English (en)
Other versions
IT1241128B (it
IT9020092A1 (it
Inventor
Jozsef Reiter
Lazzlo Pongo
Frigyes Gorgenyi
Marton Fekete
Margit Csorgo
Ilona Sztuhar
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from HU193189A external-priority patent/HU203342B/hu
Priority claimed from HU193089A external-priority patent/HU203333B/hu
Application filed by Egyt Gyogyszervegyeszeti Gyar filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of IT9020092A0 publication Critical patent/IT9020092A0/it
Publication of IT9020092A1 publication Critical patent/IT9020092A1/it
Application granted granted Critical
Publication of IT1241128B publication Critical patent/IT1241128B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/24Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IT20092A 1989-04-21 1990-04-20 Procedimento per la preparazione di derivati chinazolinici IT1241128B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU193189A HU203342B (en) 1989-04-21 1989-04-21 Process for producing quinazoline deivatives
HU193089A HU203333B (en) 1989-04-21 1989-04-21 Process for producing n-cyano-carboxamidine derivatives

Publications (3)

Publication Number Publication Date
IT9020092A0 true IT9020092A0 (it) 1990-04-20
IT9020092A1 IT9020092A1 (it) 1991-10-20
IT1241128B IT1241128B (it) 1993-12-29

Family

ID=26317437

Family Applications (1)

Application Number Title Priority Date Filing Date
IT20092A IT1241128B (it) 1989-04-21 1990-04-20 Procedimento per la preparazione di derivati chinazolinici

Country Status (16)

Country Link
JP (1) JPH02292282A (it)
KR (1) KR900016194A (it)
AT (1) AT398075B (it)
BG (1) BG91821A (it)
CA (2) CA2028953A1 (it)
CH (1) CH681300A5 (it)
DK (1) DK99090A (it)
ES (1) ES2019826A6 (it)
FI (1) FI902002A0 (it)
GB (1) GB2231571B (it)
GR (1) GR900100294A (it)
IT (1) IT1241128B (it)
PL (1) PL162976B1 (it)
RU (1) RU1838309C (it)
SE (1) SE9001402L (it)
YU (1) YU70890A (it)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
ES2096518B1 (es) * 1994-03-28 1997-12-01 Grupo Farmaceutico Almirall S Nuevas anilinas.
WO2008015525A2 (en) * 2006-07-31 2008-02-07 Orchid Chemicals & Pharmaceuticals Limited An improved process for the preparation of alfuzosin hydrochloride
WO2008152514A2 (en) 2007-05-04 2008-12-18 Actavis Group Ptc Ehf Process for the preparation of alfuzosin and salts thereof
KR20100044239A (ko) 2007-08-02 2010-04-29 시플라 리미티드 알푸조신 염산염의 제조방법

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4044135A (en) * 1975-10-14 1977-08-23 Abbott Laboratories Antihypertensive agents
US4026894A (en) * 1975-10-14 1977-05-31 Abbott Laboratories Antihypertensive agents
GB1591490A (en) * 1977-08-04 1981-06-24 Abbott Lab 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-tetrahydrofuroyl)piperazine hydrochloride dihydrate
US4138561A (en) * 1977-09-30 1979-02-06 Bristol-Myers Company Cyanocarboxamidines and quinazoline process
FI56836C (fi) * 1977-10-25 1980-04-10 Fermion Oy 4-substituerade piperazin-1-(n-aryl-n'-cyano)-karboximidamider som aer mellanprodukter vid framstaellningen av farmakologiskt vaerdefulla 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner
FI57751C (fi) * 1977-10-25 1980-10-10 Fermion Oy Foerfarande foer framstaellning av 6,7-dimetoxi- eller 6,7,8-trimetoxi-4-amino-2-(4-substituerade-piperazin-1-yl)-kinazoliner med blodtryckssaenkande verkan
FR2421888A1 (fr) * 1978-02-06 1979-11-02 Synthelabo Amides d'alkylene-diamines et leur application en therapeutique
FI59800C (fi) * 1979-01-10 1981-10-12 Fermion Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(furo-2-yl)-piperazin-1-yl)-kinazolin
FI67699C (fi) * 1979-01-31 1985-05-10 Orion Yhtymae Oy Foerfarande foer framstaellning av 6,7-dimetoxi-4-amino-2-(4-(2-furoyl)-1-piperazinyl)kinazolinhydroklorid med blodtryckssaenkande verkan
ATE32074T1 (de) * 1983-11-22 1988-02-15 Heumann Ludwig & Co Gmbh Verfahren zur herstellung von 4-amino-6,7dimethoxy-2-(4-(furo-2-yl)-piperazin-1-yl)chinazolin und dessen physiologisch annehmbarer salze.

Also Published As

Publication number Publication date
DK99090D0 (da) 1990-04-20
ES2019826A6 (es) 1991-07-01
BG91821A (bg) 1993-12-24
ATA93190A (de) 1994-01-15
KR900016194A (ko) 1990-11-12
CA2015066A1 (en) 1990-10-21
SE9001402L (sv) 1990-10-22
FI902002A0 (fi) 1990-04-20
GB2231571B (en) 1992-09-16
PL162976B1 (pl) 1994-01-31
JPH02292282A (ja) 1990-12-03
IT1241128B (it) 1993-12-29
GB9008941D0 (en) 1990-06-20
GR900100294A (el) 1991-09-27
GB2231571A (en) 1990-11-21
DK99090A (da) 1990-10-22
YU70890A (en) 1992-05-28
IT9020092A1 (it) 1991-10-20
AT398075B (de) 1994-09-26
PL284860A1 (en) 1991-03-11
CH681300A5 (it) 1993-02-26
CA2028953A1 (en) 1990-10-22
RU1838309C (ru) 1993-08-30
SE9001402D0 (sv) 1990-04-20

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940428