ITTO930346A0 - Procedimento per la preparazione di derivati taurocolanici. - Google Patents

Procedimento per la preparazione di derivati taurocolanici.

Info

Publication number
ITTO930346A0
ITTO930346A0 ITTO930346A ITTO930346A ITTO930346A0 IT TO930346 A0 ITTO930346 A0 IT TO930346A0 IT TO930346 A ITTO930346 A IT TO930346A IT TO930346 A ITTO930346 A IT TO930346A IT TO930346 A0 ITTO930346 A0 IT TO930346A0
Authority
IT
Italy
Prior art keywords
taurocholane
derivatives
procedure
preparation
taurocholane derivatives
Prior art date
Application number
ITTO930346A
Other languages
English (en)
Inventor
Roberto Arosio
Vittorio Rossetti
Original Assignee
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Elf filed Critical Sanofi Elf
Publication of ITTO930346A0 publication Critical patent/ITTO930346A0/it
Priority to ITTO930346A priority Critical patent/IT1270853B/it
Priority to ES94401103T priority patent/ES2117223T3/es
Priority to DE69408599T priority patent/DE69408599T2/de
Priority to EP94401103A priority patent/EP0629634B1/fr
Priority to DK94401103T priority patent/DK0629634T3/da
Priority to AT94401103T priority patent/ATE163423T1/de
Priority to JP6105262A priority patent/JPH0717997A/ja
Priority to US08/246,148 priority patent/US5508453A/en
Publication of ITTO930346A1 publication Critical patent/ITTO930346A1/it
Priority to US08/458,618 priority patent/US5565587A/en
Application granted granted Critical
Publication of IT1270853B publication Critical patent/IT1270853B/it
Priority to GR980400795T priority patent/GR3026599T3/el

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J9/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C07J41/0061Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
ITTO930346A 1993-05-20 1993-05-20 Procedimento per la preparazione di derivati taurocolanici IT1270853B (it)

Priority Applications (10)

Application Number Priority Date Filing Date Title
ITTO930346A IT1270853B (it) 1993-05-20 1993-05-20 Procedimento per la preparazione di derivati taurocolanici
DK94401103T DK0629634T3 (da) 1993-05-20 1994-05-18 Fremgangsmåde til fremstilling af taurocholansyrer
DE69408599T DE69408599T2 (de) 1993-05-20 1994-05-18 Verfahren zur Herstellung von Taurocholansäure
EP94401103A EP0629634B1 (fr) 1993-05-20 1994-05-18 Procédé pour la préparation d'acides taurocholaniques
ES94401103T ES2117223T3 (es) 1993-05-20 1994-05-18 Procedimiento para la preparacion de acidos taurocolanicos.
AT94401103T ATE163423T1 (de) 1993-05-20 1994-05-18 Verfahren zur herstellung von taurocholansäure
JP6105262A JPH0717997A (ja) 1993-05-20 1994-05-19 タウロコラン酸の製造方法
US08/246,148 US5508453A (en) 1993-05-20 1994-05-19 Intermediate for use in the preparation of taurocholanic acids
US08/458,618 US5565587A (en) 1993-05-20 1995-06-02 Process for the preparation of taurocholanic acids
GR980400795T GR3026599T3 (en) 1993-05-20 1998-04-10 Process for the preparation of taurocholic acids.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITTO930346A IT1270853B (it) 1993-05-20 1993-05-20 Procedimento per la preparazione di derivati taurocolanici

Publications (3)

Publication Number Publication Date
ITTO930346A0 true ITTO930346A0 (it) 1993-05-20
ITTO930346A1 ITTO930346A1 (it) 1994-11-20
IT1270853B IT1270853B (it) 1997-05-13

Family

ID=11411490

Family Applications (1)

Application Number Title Priority Date Filing Date
ITTO930346A IT1270853B (it) 1993-05-20 1993-05-20 Procedimento per la preparazione di derivati taurocolanici

Country Status (9)

Country Link
US (2) US5508453A (it)
EP (1) EP0629634B1 (it)
JP (1) JPH0717997A (it)
AT (1) ATE163423T1 (it)
DE (1) DE69408599T2 (it)
DK (1) DK0629634T3 (it)
ES (1) ES2117223T3 (it)
GR (1) GR3026599T3 (it)
IT (1) IT1270853B (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1270853B (it) * 1993-05-20 1997-05-13 Sanofi Elf Procedimento per la preparazione di derivati taurocolanici
DE4432708A1 (de) * 1994-09-14 1996-03-21 Hoechst Ag Modifizierte Gallensäuren, Verfahren zu ihrer Herstellung und ihre Verwendung
JP2002543216A (ja) 1999-04-30 2002-12-17 アーチ ディベロップメント コーポレイション ステロイド誘導体
RU2196914C2 (ru) * 2001-02-02 2003-01-20 Захаров Евгений Николаевич Силовая установка летательного аппарата
EP1385868A4 (en) * 2001-02-08 2004-12-08 Univ Chicago STEROID DERIVATIVE
ATE375994T1 (de) * 2001-05-03 2007-11-15 Univ Chicago Leber x rezeptoragonisten
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
EP1494533A2 (en) * 2002-04-12 2005-01-12 The University of Chicago Farnesoid x-activated receptor agonists
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
US7584924B2 (en) * 2006-04-11 2009-09-08 Go Aircraft Ltd. High speed vertical take-off and land aircraft with active fan balancing system
EP1985622A1 (en) * 2007-04-23 2008-10-29 Prodotti Chimici E Alimentari Spa Process for the preparation of tauroursodesoxycholic acid
CA2769203A1 (en) * 2009-07-29 2011-02-03 University Of Chicago Liver x receptor agonists
CN102477059B (zh) * 2010-11-22 2014-07-30 成都国为医药科技有限公司 一种高纯度牛磺熊去氧胆酸及其制备方法
US10260905B2 (en) 2016-06-08 2019-04-16 Allegro Microsystems, Llc Arrangements for magnetic field sensors to cancel offset variations
WO2020117945A1 (en) 2018-12-04 2020-06-11 President And Fellows Of Harvard College Synthetic derivatives of cholic acid 7-sulfate and uses thereof
IT201900005906A1 (it) 2019-04-16 2020-10-16 Dipharma Francis Srl Procedimento di preparazione di coniugati di un acido colanico
CA3137308A1 (en) * 2019-05-10 2020-11-19 Abigail Sloan Devlin Small molecule modulators of gut bacterial bile acid metabolism
IT201900018110A1 (it) * 2019-10-07 2021-04-07 Dipharma Francis Srl Sintesi di derivati glicoconiugati di un acido biliare

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3622669A (en) * 1967-10-23 1971-11-23 Merck & Co Inc 5{62 -taurocholenic acids and 5{62 -taurocholadienic acids in compositions for reducing the concentration of cholesterol and liads in blood serum
US4088760A (en) * 1976-06-23 1978-05-09 Richardson-Merrell Inc. Testosterone 5α-reductase inhibitors
US4104285A (en) * 1977-04-22 1978-08-01 Hoffmann-La Roche Inc. Taurine and glycine derivatives
IT1212835B (it) * 1983-08-18 1989-11-30 Lehner Ag Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT1197330B (it) * 1986-10-03 1988-11-30 Prodotti Chimici Alimentari Procedimento per la sintesi di acido tauroursodesossicolico biidrato
HU206367B (en) * 1988-04-30 1992-10-28 Sandoz Ag Process for producing acid addition salts of steroid carboxylic acid-amidated taurine and glycine, as well as pharmaceutical compositions comprising such salts
IT1230796B (it) * 1989-05-30 1991-10-29 Prodotti Chimici Alimentari Procedimento per la preparazione di acido tauroursodesossicolico biidrato.
IT1247489B (it) * 1991-04-17 1994-12-17 Prodotti Chimici Alimentari Acido metiltauroursodesossicolico e suoi derivati terapeuticamente attivi procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
US5352682A (en) * 1993-03-08 1994-10-04 Digestive Care Inc. Compositions containing salts of bile acid-aminosalicylate conjugates
IT1270853B (it) * 1993-05-20 1997-05-13 Sanofi Elf Procedimento per la preparazione di derivati taurocolanici

Also Published As

Publication number Publication date
EP0629634A2 (fr) 1994-12-21
IT1270853B (it) 1997-05-13
DE69408599T2 (de) 1998-09-24
JPH0717997A (ja) 1995-01-20
US5508453A (en) 1996-04-16
ATE163423T1 (de) 1998-03-15
EP0629634A3 (fr) 1995-12-27
EP0629634B1 (fr) 1998-02-25
ITTO930346A1 (it) 1994-11-20
GR3026599T3 (en) 1998-07-31
ES2117223T3 (es) 1998-08-01
DE69408599D1 (de) 1998-04-02
DK0629634T3 (da) 1998-09-28
US5565587A (en) 1996-10-15

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Legal Events

Date Code Title Description
0001 Granted
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970530