GR3026599T3 - Process for the preparation of taurocholic acids. - Google Patents

Process for the preparation of taurocholic acids.

Info

Publication number
GR3026599T3
GR3026599T3 GR980400795T GR980400795T GR3026599T3 GR 3026599 T3 GR3026599 T3 GR 3026599T3 GR 980400795 T GR980400795 T GR 980400795T GR 980400795 T GR980400795 T GR 980400795T GR 3026599 T3 GR3026599 T3 GR 3026599T3
Authority
GR
Greece
Prior art keywords
preparation
acids
intermediates
taurocholic acids
taurocholic
Prior art date
Application number
GR980400795T
Other languages
English (en)
Inventor
Roberto Arosio
Vittorio Rossetti
Original Assignee
Sanofi Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Sa filed Critical Sanofi Sa
Publication of GR3026599T3 publication Critical patent/GR3026599T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • C07J9/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane containing a carboxylic function directly attached or attached by a chain containing only carbon atoms to the cyclopenta[a]hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • C07J41/0061—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives one of the carbon atoms being part of an amide group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
GR980400795T 1993-05-20 1998-04-10 Process for the preparation of taurocholic acids. GR3026599T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITTO930346A IT1270853B (it) 1993-05-20 1993-05-20 Procedimento per la preparazione di derivati taurocolanici

Publications (1)

Publication Number Publication Date
GR3026599T3 true GR3026599T3 (en) 1998-07-31

Family

ID=11411490

Family Applications (1)

Application Number Title Priority Date Filing Date
GR980400795T GR3026599T3 (en) 1993-05-20 1998-04-10 Process for the preparation of taurocholic acids.

Country Status (9)

Country Link
US (2) US5508453A (el)
EP (1) EP0629634B1 (el)
JP (1) JPH0717997A (el)
AT (1) ATE163423T1 (el)
DE (1) DE69408599T2 (el)
DK (1) DK0629634T3 (el)
ES (1) ES2117223T3 (el)
GR (1) GR3026599T3 (el)
IT (1) IT1270853B (el)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1270853B (it) * 1993-05-20 1997-05-13 Sanofi Elf Procedimento per la preparazione di derivati taurocolanici
DE4432708A1 (de) * 1994-09-14 1996-03-21 Hoechst Ag Modifizierte Gallensäuren, Verfahren zu ihrer Herstellung und ihre Verwendung
CN1187364C (zh) 1999-04-30 2005-02-02 亚其发展公司 类固醇衍生物
EP1385868A4 (en) * 2001-02-08 2004-12-08 Univ Chicago STEROID DERIVATIVES
US7078396B2 (en) * 2001-05-03 2006-07-18 Arch Development Corporation Method of treating disorder related to high cholesterol concentration
US20070197484A1 (en) * 2001-05-03 2007-08-23 Ching Song Method of treating disorder related to high cholesterol concentration
ES2296928T3 (es) * 2001-05-03 2008-05-01 The University Of Chicago Receptores x hepaticos.
WO2003086303A2 (en) * 2002-04-12 2003-10-23 The University Of Chicago Farnesoid x-activated receptor agonists
US20070032464A1 (en) * 2004-10-08 2007-02-08 Shutsung Liao Methods of treating cancers
US7584924B2 (en) * 2006-04-11 2009-09-08 Go Aircraft Ltd. High speed vertical take-off and land aircraft with active fan balancing system
EP1985622A1 (en) * 2007-04-23 2008-10-29 Prodotti Chimici E Alimentari Spa Process for the preparation of tauroursodesoxycholic acid
EP2459581A4 (en) * 2009-07-29 2012-12-26 Univ Chicago LIVER X RECEPTOR AGONISTS
CN102477059B (zh) * 2010-11-22 2014-07-30 成都国为医药科技有限公司 一种高纯度牛磺熊去氧胆酸及其制备方法
US10260905B2 (en) 2016-06-08 2019-04-16 Allegro Microsystems, Llc Arrangements for magnetic field sensors to cancel offset variations
IT201900005906A1 (it) 2019-04-16 2020-10-16 Dipharma Francis Srl Procedimento di preparazione di coniugati di un acido colanico
IT201900018110A1 (it) * 2019-10-07 2021-04-07 Dipharma Francis Srl Sintesi di derivati glicoconiugati di un acido biliare

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3622669A (en) * 1967-10-23 1971-11-23 Merck & Co Inc 5{62 -taurocholenic acids and 5{62 -taurocholadienic acids in compositions for reducing the concentration of cholesterol and liads in blood serum
US4088760A (en) * 1976-06-23 1978-05-09 Richardson-Merrell Inc. Testosterone 5α-reductase inhibitors
US4104285A (en) * 1977-04-22 1978-08-01 Hoffmann-La Roche Inc. Taurine and glycine derivatives
IT1212835B (it) * 1983-08-18 1989-11-30 Lehner Ag Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche.
IT1197330B (it) * 1986-10-03 1988-11-30 Prodotti Chimici Alimentari Procedimento per la sintesi di acido tauroursodesossicolico biidrato
HU206367B (en) * 1988-04-30 1992-10-28 Sandoz Ag Process for producing acid addition salts of steroid carboxylic acid-amidated taurine and glycine, as well as pharmaceutical compositions comprising such salts
IT1230796B (it) * 1989-05-30 1991-10-29 Prodotti Chimici Alimentari Procedimento per la preparazione di acido tauroursodesossicolico biidrato.
IT1247489B (it) * 1991-04-17 1994-12-17 Prodotti Chimici Alimentari Acido metiltauroursodesossicolico e suoi derivati terapeuticamente attivi procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
US5352682A (en) * 1993-03-08 1994-10-04 Digestive Care Inc. Compositions containing salts of bile acid-aminosalicylate conjugates
IT1270853B (it) * 1993-05-20 1997-05-13 Sanofi Elf Procedimento per la preparazione di derivati taurocolanici

Also Published As

Publication number Publication date
ATE163423T1 (de) 1998-03-15
DK0629634T3 (da) 1998-09-28
JPH0717997A (ja) 1995-01-20
DE69408599T2 (de) 1998-09-24
US5565587A (en) 1996-10-15
EP0629634A2 (fr) 1994-12-21
US5508453A (en) 1996-04-16
ITTO930346A0 (it) 1993-05-20
EP0629634A3 (fr) 1995-12-27
ITTO930346A1 (it) 1994-11-20
IT1270853B (it) 1997-05-13
EP0629634B1 (fr) 1998-02-25
DE69408599D1 (de) 1998-04-02
ES2117223T3 (es) 1998-08-01

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