ATE111073T1 - Neue zwischenprodukte, ihre herstellung und verwendung. - Google Patents

Neue zwischenprodukte, ihre herstellung und verwendung.

Info

Publication number
ATE111073T1
ATE111073T1 AT90917427T AT90917427T ATE111073T1 AT E111073 T1 ATE111073 T1 AT E111073T1 AT 90917427 T AT90917427 T AT 90917427T AT 90917427 T AT90917427 T AT 90917427T AT E111073 T1 ATE111073 T1 AT E111073T1
Authority
AT
Austria
Prior art keywords
pct
stands
sec
aryl
hydrogen
Prior art date
Application number
AT90917427T
Other languages
English (en)
Inventor
Frantz Johannes Lund
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Application granted granted Critical
Publication of ATE111073T1 publication Critical patent/ATE111073T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C329/00—Thiocarbonic acids; Halides, esters or anhydrides thereof
    • C07C329/02—Monothiocarbonic acids; Derivatives thereof
    • C07C329/04—Esters of monothiocarbonic acids
    • C07C329/06—Esters of monothiocarbonic acids having sulfur atoms of thiocarbonic groups bound to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/96—Esters of carbonic or haloformic acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT90917427T 1990-01-22 1990-11-28 Neue zwischenprodukte, ihre herstellung und verwendung. ATE111073T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909001405A GB9001405D0 (en) 1990-01-22 1990-01-22 New intermediates,their production and use

Publications (1)

Publication Number Publication Date
ATE111073T1 true ATE111073T1 (de) 1994-09-15

Family

ID=10669692

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90917427T ATE111073T1 (de) 1990-01-22 1990-11-28 Neue zwischenprodukte, ihre herstellung und verwendung.

Country Status (13)

Country Link
US (1) US5401868A (de)
EP (1) EP0541550B1 (de)
JP (1) JP3025532B2 (de)
AT (1) ATE111073T1 (de)
AU (1) AU6883191A (de)
CA (1) CA2064872C (de)
DE (1) DE69012351T2 (de)
DK (1) DK0541550T3 (de)
ES (1) ES2061077T3 (de)
GB (1) GB9001405D0 (de)
HU (1) HUT60459A (de)
IE (1) IE64470B1 (de)
WO (1) WO1991010639A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001005768A1 (fr) 1999-07-19 2001-01-25 Shionogi & Co., Ltd. Composes tricycliques porteurs de pendants acyloxymethoxycarbonyle
JP2004501067A (ja) * 2000-01-28 2004-01-15 ローム　アンド　ハース　カンパニー 高められた特性をもつ医薬
US6376548B1 (en) 2000-01-28 2002-04-23 Rohm And Haas Company Enhanced propertied pesticides
US6818787B2 (en) * 2001-06-11 2004-11-16 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
US7232924B2 (en) * 2001-06-11 2007-06-19 Xenoport, Inc. Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
US7186855B2 (en) 2001-06-11 2007-03-06 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
EP1404324B2 (de) * 2001-06-11 2011-04-06 XenoPort, Inc. Prodrugs von gaba-analoga, zusammensetzungen und ihre verwendungszwecke
US8048917B2 (en) 2005-04-06 2011-11-01 Xenoport, Inc. Prodrugs of GABA analogs, compositions and uses thereof
WO2003077902A1 (en) * 2002-02-19 2003-09-25 Xenoport, Inc. Methods for synthesis of prodrugs from 1-acyl-alkyl derivatives and compositions thereof
PA8579701A1 (es) * 2002-08-23 2005-05-24 Pfizer Prod Inc Profarmaco inhibidor de beta-lactamasa
EP1636240A1 (de) * 2003-06-05 2006-03-22 Pfizer Products Inc. Beta-lactamasehemmer prodrug
US7662987B2 (en) * 2003-07-15 2010-02-16 Xenoport, Inc. Methods for synthesis of acyloxyalkyl compounds
KR20110097942A (ko) * 2003-08-20 2011-08-31 제노포트 인코포레이티드 아실옥시알킬 카르바메이트 프로드러그, 합성 및 사용 방법
CN1902175B (zh) * 2003-12-30 2012-08-22 什诺波特有限公司 酰氧基烃基氨基甲酸酯前药及其中间体的合成
JP4927563B2 (ja) * 2003-12-30 2012-05-09 ゼノポート，インコーポレイティド アシルオキシアルキルカルバメートプロドラッグ及び中間体の合成
AU2006262386B2 (en) 2005-06-20 2012-02-02 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs of tranexamic acid, methods of synthesis and use
TW200820963A (en) * 2006-07-28 2008-05-16 Xenoport Inc Acyloxyalkyl carbamate prodrugs of α-amino acids, methods of synthesis and use
US20090318728A1 (en) * 2008-06-24 2009-12-24 Teva Pharmaceutical Industries Ltd. Processes for preparing prodrugs of gabapentin and intermediates thereof
WO2011028234A1 (en) * 2009-09-04 2011-03-10 Xenoport, Inc. Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
JP6105207B2 (ja) * 2012-03-30 2017-03-29 美津濃株式会社 ラケットフレーム
US20140024621A1 (en) 2012-07-23 2014-01-23 Ms Therapeutics Limited Aminopyridine compounds and their uses
US20230000812A1 (en) * 2020-08-13 2023-01-05 Nanjing Heron Pharmaceutical Science And Technology Co., Ltd. Ibuprofen ester prodrug, pharmaceutical composition, preparation method and application

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3479328A (en) * 1966-11-18 1969-11-18 Ashland Oil Inc Novel monomers and polymers
US3769271A (en) * 1971-04-15 1973-10-30 Lilly Co Eli N-protected amino acids and peptides
FR2363546A1 (fr) * 1976-09-07 1978-03-31 Poudres & Explosifs Ste Nale Monomeres mixtes allyliques-acryliques, leur preparation et polymeres en derivant
DE2939660A1 (de) * 1979-09-29 1981-04-16 Basf Ag, 6700 Ludwigshafen Neue carbamate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen
JPS58189186A (ja) * 1982-04-30 1983-11-04 Takeda Chem Ind Ltd セフアロスポリン誘導体
IL67445A (en) * 1982-12-09 1985-11-29 Teva Pharma Ethoxycarbonyloxy ethyl esters of non-steroidal anti-inflammatory carboxylic acids
DE3301670A1 (de) * 1983-01-20 1984-07-26 Bayer Ag, 5090 Leverkusen Leimungsmittel
US5221754A (en) * 1989-06-09 1993-06-22 Research Corporation Technologies, Inc. Reagents for rapid peptide synthesis

Also Published As

Publication number Publication date
DK0541550T3 (da) 1994-10-17
IE904309A1 (en) 1991-07-31
JPH05503925A (ja) 1993-06-24
IE64470B1 (en) 1995-08-09
WO1991010639A1 (en) 1991-07-25
CA2064872A1 (en) 1991-07-23
DE69012351T2 (de) 1995-02-09
CA2064872C (en) 2002-01-22
DE69012351D1 (de) 1994-10-13
JP3025532B2 (ja) 2000-03-27
EP0541550A1 (de) 1993-05-19
HUT60459A (en) 1992-09-28
HU9200477D0 (en) 1992-08-28
US5401868A (en) 1995-03-28
GB9001405D0 (en) 1990-03-21
ES2061077T3 (es) 1994-12-01
AU6883191A (en) 1991-08-05
EP0541550B1 (de) 1994-09-07

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Legal Events

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