ATE138571T1 - Verwendung von dioxabicyclo (3.3.0>octane derivaten zur herstellung eines arzneimittels zur hemmung des cholesterinmetabolismus. - Google Patents
Verwendung von dioxabicyclo (3.3.0>octane derivaten zur herstellung eines arzneimittels zur hemmung des cholesterinmetabolismus.Info
- Publication number
- ATE138571T1 ATE138571T1 AT91309685T AT91309685T ATE138571T1 AT E138571 T1 ATE138571 T1 AT E138571T1 AT 91309685 T AT91309685 T AT 91309685T AT 91309685 T AT91309685 T AT 91309685T AT E138571 T1 ATE138571 T1 AT E138571T1
- Authority
- AT
- Austria
- Prior art keywords
- dioxabicyclo
- drug
- production
- cholesterol metabolism
- inhibiting cholesterol
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 230000002401 inhibitory effect Effects 0.000 title abstract 2
- 230000004060 metabolic process Effects 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- TVMXDCGIABBOFY-UHFFFAOYSA-N octane Chemical class CCCCCCCC TVMXDCGIABBOFY-UHFFFAOYSA-N 0.000 title 1
- XNWFXTOHNKPYMK-UHFFFAOYSA-N 3,3a,4,5,6,6a-hexahydrocyclopenta[c]dioxole Chemical class C1OOC2CCCC21 XNWFXTOHNKPYMK-UHFFFAOYSA-N 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 125000000816 ethylene group Chemical group [H]C([H])([*:1])C([H])([H])[*:2] 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000001570 methylene group Chemical group [H]C([H])([*:1])[*:2] 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
- A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Medicines Containing Plant Substances (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28183990A JP3183664B2 (ja) | 1990-10-22 | 1990-10-22 | コレステロール及び胆汁酸の代謝阻害剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE138571T1 true ATE138571T1 (de) | 1996-06-15 |
Family
ID=17644733
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT91309685T ATE138571T1 (de) | 1990-10-22 | 1991-10-21 | Verwendung von dioxabicyclo (3.3.0>octane derivaten zur herstellung eines arzneimittels zur hemmung des cholesterinmetabolismus. |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5270335A (de) |
| EP (1) | EP0488513B1 (de) |
| JP (1) | JP3183664B2 (de) |
| AT (1) | ATE138571T1 (de) |
| CA (1) | CA2053820C (de) |
| DE (1) | DE69119875T2 (de) |
| DK (1) | DK0488513T3 (de) |
| ES (1) | ES2087252T3 (de) |
| GR (1) | GR3020682T3 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3283274B2 (ja) * | 1991-06-15 | 2002-05-20 | サントリー株式会社 | 新規組成物 |
| JPH06227977A (ja) * | 1993-02-01 | 1994-08-16 | Suntory Ltd | 活性酸素消去剤 |
| JPH10500937A (ja) * | 1994-02-25 | 1998-01-27 | ニュー イングランド ディーコネス ホスピタル コーポレイション | セサミン系リグナンの抗炎症及び感染防護効果 |
| US5397778A (en) * | 1994-02-25 | 1995-03-14 | New England Deaconess Hospital Corporation | Enteral formulations for treatment of inflammation and infection |
| JP3818680B2 (ja) * | 1994-05-12 | 2006-09-06 | サントリー株式会社 | アレルギー症状の予防又は改善剤 |
| DK0782827T3 (da) * | 1995-07-04 | 2004-02-09 | Suntory Ltd | Anvendelse af et afbalanceringsmiddel til omega-6- og omega-3-umættede fedtsyrer |
| JPH11246427A (ja) * | 1998-03-04 | 1999-09-14 | Kadoya Sesami Mills Inc | 糖・脂質代謝活性化剤 |
| KR100352269B1 (ko) * | 1999-10-08 | 2002-09-12 | 한국생명공학연구원 | 저밀도 지질 단백질에 대해 항산화 활성을 갖는 리그난계 화합물 |
| JP4388248B2 (ja) * | 2001-10-29 | 2009-12-24 | 株式会社日立製作所 | 最適ポートフォリオ決定方法および装置 |
| US7081260B2 (en) * | 2002-10-29 | 2006-07-25 | Council Of Scientific And Industrial Research | α-Glucosidase inhibitors from a natural source |
| CA2603347C (en) * | 2005-03-31 | 2014-06-17 | Suntory Limited | Oil-in-water emulsions of lignans that exhibit improved absorption rate |
| WO2007037385A1 (ja) | 2005-09-30 | 2007-04-05 | Suntory Limited | エピセサミン高含有組成物の製造方法及び装置 |
| US9408803B2 (en) | 2006-03-31 | 2016-08-09 | Suntory Holdings Limited | Compositions containing lignan-class compounds |
| AU2007305614B2 (en) | 2006-10-04 | 2012-08-23 | Suntory Holdings Limited | O/W/O emulsion containing lignan compounds and composition containing the same |
| JP5051878B2 (ja) * | 2007-03-02 | 2012-10-17 | 竹本油脂株式会社 | 高濃度セサミノール含有物の製造方法 |
| SG10201510301UA (en) | 2007-09-19 | 2016-01-28 | Suntory Holdings Ltd | Compositions incorporating sesamin-class compounds and vitamin b1 class compounds |
| JP7366991B2 (ja) * | 2019-02-28 | 2023-10-23 | 株式会社えがお | 体重増加抑制・低減用組成物 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2235205T3 (es) * | 1989-07-21 | 2005-07-01 | Suntory Limited | Capsula que contiene compuestos de dioxabiciclo (3.3.0)octano. |
-
1990
- 1990-10-22 JP JP28183990A patent/JP3183664B2/ja not_active Expired - Lifetime
-
1991
- 1991-10-21 DK DK91309685.5T patent/DK0488513T3/da active
- 1991-10-21 DE DE69119875T patent/DE69119875T2/de not_active Expired - Lifetime
- 1991-10-21 CA CA002053820A patent/CA2053820C/en not_active Expired - Lifetime
- 1991-10-21 EP EP91309685A patent/EP0488513B1/de not_active Expired - Lifetime
- 1991-10-21 US US07/779,998 patent/US5270335A/en not_active Expired - Lifetime
- 1991-10-21 AT AT91309685T patent/ATE138571T1/de not_active IP Right Cessation
- 1991-10-21 ES ES91309685T patent/ES2087252T3/es not_active Expired - Lifetime
-
1996
- 1996-07-31 GR GR960402040T patent/GR3020682T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| ES2087252T3 (es) | 1996-07-16 |
| DE69119875D1 (de) | 1996-07-04 |
| EP0488513A3 (de) | 1992-06-17 |
| EP0488513A2 (de) | 1992-06-03 |
| DE69119875T2 (de) | 1996-10-02 |
| US5270335A (en) | 1993-12-14 |
| CA2053820C (en) | 1997-02-04 |
| EP0488513B1 (de) | 1996-05-29 |
| DK0488513T3 (da) | 1996-06-17 |
| CA2053820A1 (en) | 1992-04-23 |
| JPH04159221A (ja) | 1992-06-02 |
| GR3020682T3 (en) | 1996-10-31 |
| JP3183664B2 (ja) | 2001-07-09 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |