ATE186907T1 - Optisch aktives 1-phenylpyrrolidonderivat und dessen herstellung - Google Patents
Optisch aktives 1-phenylpyrrolidonderivat und dessen herstellungInfo
- Publication number
- ATE186907T1 ATE186907T1 AT93919628T AT93919628T ATE186907T1 AT E186907 T1 ATE186907 T1 AT E186907T1 AT 93919628 T AT93919628 T AT 93919628T AT 93919628 T AT93919628 T AT 93919628T AT E186907 T1 ATE186907 T1 AT E186907T1
- Authority
- AT
- Austria
- Prior art keywords
- optically active
- production
- synthesis
- inhibit
- activity
- Prior art date
Links
- JMVIVASFFKKFQK-UHFFFAOYSA-N 1-phenylpyrrolidin-2-one Chemical class O=C1CCCN1C1=CC=CC=C1 JMVIVASFFKKFQK-UHFFFAOYSA-N 0.000 title 1
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 abstract 2
- 238000003786 synthesis reaction Methods 0.000 abstract 2
- 208000031226 Hyperlipidaemia Diseases 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 235000012000 cholesterol Nutrition 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 235000014113 dietary fatty acids Nutrition 0.000 abstract 1
- 229930195729 fatty acid Natural products 0.000 abstract 1
- 239000000194 fatty acid Substances 0.000 abstract 1
- 150000004665 fatty acids Chemical class 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 238000001308 synthesis method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pyrrole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP24288792 | 1992-09-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE186907T1 true ATE186907T1 (de) | 1999-12-15 |
Family
ID=17095708
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98203959T ATE309212T1 (de) | 1992-09-11 | 1993-09-08 | Optisch aktive 1-phenylpyrrolidonderivate |
| AT93919628T ATE186907T1 (de) | 1992-09-11 | 1993-09-08 | Optisch aktives 1-phenylpyrrolidonderivat und dessen herstellung |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT98203959T ATE309212T1 (de) | 1992-09-11 | 1993-09-08 | Optisch aktive 1-phenylpyrrolidonderivate |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5475118A (de) |
| EP (2) | EP0627419B1 (de) |
| JP (1) | JP2724634B2 (de) |
| KR (1) | KR0141657B1 (de) |
| AT (2) | ATE309212T1 (de) |
| AU (1) | AU663233B2 (de) |
| CA (1) | CA2122705C (de) |
| DE (2) | DE69333903T2 (de) |
| DK (1) | DK0627419T3 (de) |
| ES (2) | ES2139670T3 (de) |
| FI (2) | FI107605B (de) |
| HU (1) | HU215598B (de) |
| NO (1) | NO300130B1 (de) |
| WO (1) | WO1994006767A1 (de) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69928749T2 (de) * | 1998-02-24 | 2006-06-29 | Taiho Pharmaceutical Co. Ltd. | Lp(a)-Senkendes Mittel und die Apolipoprotein(a)-Bildung unterdrückendes Mittel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69025418T2 (de) * | 1989-04-19 | 1996-11-14 | Otsuka Pharma Co Ltd | Phenylcarbonsäurederivate mit einem Heterocyclus |
| JPH06192221A (ja) * | 1992-12-25 | 1994-07-12 | Taiho Yakuhin Kogyo Kk | 光学活性な１−（４−ｔ−ブチルフェニル）−５−オキソ−３−ピロリジンカルボン酸の製造方法 |
-
1993
- 1993-09-08 JP JP6507962A patent/JP2724634B2/ja not_active Expired - Lifetime
- 1993-09-08 US US08/211,950 patent/US5475118A/en not_active Expired - Fee Related
- 1993-09-08 DE DE69333903T patent/DE69333903T2/de not_active Expired - Fee Related
- 1993-09-08 ES ES93919628T patent/ES2139670T3/es not_active Expired - Lifetime
- 1993-09-08 DE DE69327092T patent/DE69327092T2/de not_active Expired - Fee Related
- 1993-09-08 DK DK93919628T patent/DK0627419T3/da active
- 1993-09-08 EP EP93919628A patent/EP0627419B1/de not_active Expired - Lifetime
- 1993-09-08 HU HU9401470A patent/HU215598B/hu not_active IP Right Cessation
- 1993-09-08 AT AT98203959T patent/ATE309212T1/de not_active IP Right Cessation
- 1993-09-08 EP EP98203959A patent/EP0916657B9/de not_active Expired - Lifetime
- 1993-09-08 ES ES98203959T patent/ES2247657T3/es not_active Expired - Lifetime
- 1993-09-08 AT AT93919628T patent/ATE186907T1/de not_active IP Right Cessation
- 1993-09-08 WO PCT/JP1993/001274 patent/WO1994006767A1/ja not_active Ceased
- 1993-09-08 CA CA002122705A patent/CA2122705C/en not_active Expired - Fee Related
- 1993-09-08 KR KR1019940701558A patent/KR0141657B1/ko not_active Expired - Fee Related
- 1993-09-08 AU AU49832/93A patent/AU663233B2/en not_active Ceased
-
1994
- 1994-05-10 FI FI942167A patent/FI107605B/fi active
- 1994-05-10 NO NO941757A patent/NO300130B1/no unknown
-
2000
- 2000-08-28 FI FI20001893A patent/FI108130B/fi active
Also Published As
| Publication number | Publication date |
|---|---|
| EP0916657B1 (de) | 2005-11-09 |
| FI107605B (fi) | 2001-09-14 |
| EP0627419A4 (de) | 1995-02-08 |
| KR0141657B1 (ko) | 1998-06-01 |
| FI942167A0 (fi) | 1994-05-10 |
| JP2724634B2 (ja) | 1998-03-09 |
| EP0916657A1 (de) | 1999-05-19 |
| FI108130B (fi) | 2001-11-30 |
| DE69327092T2 (de) | 2000-05-25 |
| NO300130B1 (no) | 1997-04-14 |
| US5475118A (en) | 1995-12-12 |
| HUT70219A (en) | 1995-09-28 |
| EP0627419A1 (de) | 1994-12-07 |
| DE69333903D1 (de) | 2005-12-15 |
| WO1994006767A1 (fr) | 1994-03-31 |
| AU663233B2 (en) | 1995-09-28 |
| DK0627419T3 (da) | 2000-04-25 |
| FI20001893L (fi) | 2000-08-28 |
| CA2122705A1 (en) | 1994-03-31 |
| EP0627419B1 (de) | 1999-11-24 |
| DE69327092D1 (de) | 1999-12-30 |
| ATE309212T1 (de) | 2005-11-15 |
| NO941757D0 (no) | 1994-05-10 |
| HU9401470D0 (en) | 1994-08-29 |
| AU4983293A (en) | 1994-04-12 |
| DE69333903T2 (de) | 2006-07-27 |
| HU215598B (hu) | 1999-01-28 |
| NO941757L (no) | 1994-05-10 |
| ES2247657T3 (es) | 2006-03-01 |
| FI942167L (fi) | 1994-07-08 |
| ES2139670T3 (es) | 2000-02-16 |
| EP0916657B9 (de) | 2006-05-17 |
| CA2122705C (en) | 1997-11-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |