ATE125256T1 - Zwischenprodukte der mureidomycin-gruppe, ihre herstellung und verwendung. - Google Patents
Zwischenprodukte der mureidomycin-gruppe, ihre herstellung und verwendung.Info
- Publication number
- ATE125256T1 ATE125256T1 AT92202494T AT92202494T ATE125256T1 AT E125256 T1 ATE125256 T1 AT E125256T1 AT 92202494 T AT92202494 T AT 92202494T AT 92202494 T AT92202494 T AT 92202494T AT E125256 T1 ATE125256 T1 AT E125256T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- carbon atoms
- mureidomycin
- compound
- tetrahydroisoquinolin
- Prior art date
Links
- 229930186802 Mureidomycin Natural products 0.000 title abstract 4
- 239000013067 intermediate product Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 150000001875 compounds Chemical class 0.000 abstract 5
- -1 8-hydroxy-1,2,3,4-tetrahydroisoquinolin-3-yl Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 2
- 229940088710 antibiotic agent Drugs 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 208000035143 Bacterial infection Diseases 0.000 abstract 1
- LLINEOOFHRQODR-UHFFFAOYSA-N Mureidomycin A Natural products CSCCC(NC(=O)NC(Cc1cccc(O)c1)C(=O)O)C(=O)NC(C(C)N(C)C(=O)C(N)Cc2cccc(O)c2)C(=O)NC=C/3CC(O)C(O3)N4C=CC(=O)NC4=O LLINEOOFHRQODR-UHFFFAOYSA-N 0.000 abstract 1
- LLINEOOFHRQODR-QQCWUGGYSA-N Mureidomycin A Chemical compound C=1C=CC(O)=CC=1CC(N)C(=O)N(C)C(C)C(C(=O)N\C=C\1O[C@H]([C@H](O)C/1)N1C(NC(=O)C=C1)=O)NC(=O)C(CCSC)NC(=O)NC(C(O)=O)CC1=CC=CC(O)=C1 LLINEOOFHRQODR-QQCWUGGYSA-N 0.000 abstract 1
- RFAFKGRDICXXEY-UHFFFAOYSA-N Mureidomycin E Natural products CSCCC(NC(=O)NC(Cc1cccc(O)c1)C(=O)O)C(=O)NC(C(C)N(C)C(=O)C2Cc3cccc(O)c3CN2)C(=O)NC=C/4CC(O)C(O4)N5C=CC(=O)NC5=O RFAFKGRDICXXEY-UHFFFAOYSA-N 0.000 abstract 1
- 241000187747 Streptomyces Species 0.000 abstract 1
- 241000958209 Streptomyces flavidovirens Species 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 125000002485 formyl group Chemical class [H]C(*)=O 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/0217—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -C(=O)-C-N-C(=O)-N-C-C(=O)-
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Compounds Of Unknown Constitution (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP29335287 | 1987-11-20 | ||
| JP29335387 | 1987-11-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE125256T1 true ATE125256T1 (de) | 1995-08-15 |
Family
ID=26559375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT92202494T ATE125256T1 (de) | 1987-11-20 | 1988-11-16 | Zwischenprodukte der mureidomycin-gruppe, ihre herstellung und verwendung. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5041423A (de) |
| EP (2) | EP0317292B1 (de) |
| KR (2) | KR0137779B1 (de) |
| AT (1) | ATE125256T1 (de) |
| CA (1) | CA1339595C (de) |
| DE (2) | DE3880092T2 (de) |
| ES (2) | ES2077345T3 (de) |
| HK (2) | HK1003573A1 (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0487756A1 (de) * | 1990-11-26 | 1992-06-03 | Hoechst Aktiengesellschaft | Antibiotika-Napsamycin A-D, deren Herstellung und pharmazeutische Verwendung |
| US6228842B1 (en) | 1998-11-06 | 2001-05-08 | Microcide Pharmaceuticals, Inc. | Pacidamycins produced by Streptomyces coeruleorubidus |
| US6482921B1 (en) * | 1999-01-28 | 2002-11-19 | Essential Therapeutics, Inc. | Uridyl peptide antibiotic (UPA) derivatives, their synthesis and use |
| IL161079A0 (en) * | 2001-09-27 | 2004-08-31 | Biocon Ltd | A strain of streptomyces flavidovirens and process for the manufacture of pravastatin utilizing the same |
| KR102302414B1 (ko) | 2014-06-20 | 2021-09-16 | 주식회사 만도 | 임피던스 저감을 위한 피씨비와 섀시간의 그라운드 결합구조 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3341571A1 (de) * | 1983-11-17 | 1985-05-30 | Bayer Ag, 5090 Leverkusen | Neue antibiotika, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel und zwischenprodukte zu ihrer herstellung |
| GB8421279D0 (en) * | 1984-08-22 | 1984-09-26 | Baldwin J E | Antibiotics |
| IT1184164B (it) * | 1985-03-19 | 1987-10-22 | Eniricerche Spa | Triptidi ad azione ipotensiva e procedimento per la loro sintesi |
| CA1339467C (en) * | 1986-05-20 | 1997-09-16 | Keiko Shimizu | New antibiotics called "mureidomycins a, b, c and d", a process for their preparation and their therapeutic use |
-
1988
- 1988-11-16 AT AT92202494T patent/ATE125256T1/de not_active IP Right Cessation
- 1988-11-16 ES ES92202494T patent/ES2077345T3/es not_active Expired - Lifetime
- 1988-11-16 DE DE88310822T patent/DE3880092T2/de not_active Expired - Fee Related
- 1988-11-16 ES ES88310822T patent/ES2054829T3/es not_active Expired - Lifetime
- 1988-11-16 DE DE3854205T patent/DE3854205T2/de not_active Expired - Fee Related
- 1988-11-16 EP EP88310822A patent/EP0317292B1/de not_active Expired - Lifetime
- 1988-11-16 EP EP92202494A patent/EP0517345B1/de not_active Expired - Lifetime
- 1988-11-17 US US07/273,199 patent/US5041423A/en not_active Expired - Fee Related
- 1988-11-19 KR KR1019880015272A patent/KR0137779B1/ko not_active Expired - Fee Related
- 1988-11-21 CA CA000583649A patent/CA1339595C/en not_active Expired - Fee Related
-
1997
- 1997-10-13 KR KR1019970056329A patent/KR0137675B1/ko not_active Expired - Fee Related
-
1998
- 1998-03-30 HK HK98102695A patent/HK1003573A1/en not_active IP Right Cessation
- 1998-06-03 HK HK98104839A patent/HK1005736A1/en not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0517345A1 (de) | 1992-12-09 |
| DE3854205D1 (de) | 1995-08-24 |
| EP0317292A3 (en) | 1990-07-25 |
| KR0137675B1 (ko) | 1998-05-15 |
| ES2054829T3 (es) | 1994-08-16 |
| EP0317292A2 (de) | 1989-05-24 |
| DE3854205T2 (de) | 1996-04-04 |
| KR890008130A (ko) | 1989-07-08 |
| DE3880092T2 (de) | 1993-11-25 |
| EP0517345B1 (de) | 1995-07-19 |
| ES2077345T3 (es) | 1995-11-16 |
| HK1003573A1 (en) | 1998-10-30 |
| KR0137779B1 (ko) | 1998-05-15 |
| HK1005736A1 (en) | 1999-01-22 |
| EP0317292B1 (de) | 1993-04-07 |
| CA1339595C (en) | 1997-12-23 |
| US5041423A (en) | 1991-08-20 |
| DE3880092D1 (de) | 1993-05-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |