ES2087252T3 - Uso de derivados de dioxabiciclo(3.3.0)octano para la preparacion de un medicamento para inhibir el metabolismo del colesterol. - Google Patents

Uso de derivados de dioxabiciclo(3.3.0)octano para la preparacion de un medicamento para inhibir el metabolismo del colesterol.

Info

Publication number
ES2087252T3
ES2087252T3 ES91309685T ES91309685T ES2087252T3 ES 2087252 T3 ES2087252 T3 ES 2087252T3 ES 91309685 T ES91309685 T ES 91309685T ES 91309685 T ES91309685 T ES 91309685T ES 2087252 T3 ES2087252 T3 ES 2087252T3
Authority
ES
Spain
Prior art keywords
cholesterol
metabolism
dioxabiciclo
octano
medication
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91309685T
Other languages
English (en)
Inventor
Kengo Akimoto
Sumio Asami
Michihiro Sugano
Nobuaki Hirose
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Suntory Ltd
Original Assignee
Suntory Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=17644733&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2087252(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Suntory Ltd filed Critical Suntory Ltd
Application granted granted Critical
Publication of ES2087252T3 publication Critical patent/ES2087252T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A61K31/36—Compounds containing methylenedioxyphenyl groups, e.g. sesamin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE DESCRIBE UN METODO PARA INHIBIR EL METABOLISMO DEL COLESTEROL, QUE CONSISTE EN LA ADMINISTRACION AL SUJETO DE UNA COMPOSICION FARMACOLOGICA QUE COMPRENDE UN DERIVADO DEL DIOXABICICLO[3.3.0]OCTANO REPRESENTADO POR LA SIGUIENTE FORMULA GENERAL (I): DONDE R ELEVADO 1, R (AL CUADRADO) , R ELEVADO 3, R ELEVADO 4 Y R ELEVADO 5 INDEPENDIENTEMENTE REPRESENTAN UN ATOMO DE HIDROGENO O UN GRUPO ALQUILO QUE TIENE DE 1 A 3 ATOMOS DE CARBONO, O R ELEVADO 1 Y R (AL CUADRADO) Y/O R ELEVADO 4 Y R ELEVADO 5 CONJUNTAMENTE FORMAN UN GRUPO METILENO O UN GRUPO ETILENO, Y N, M Y L SON 0 O 1.
ES91309685T 1990-10-22 1991-10-21 Uso de derivados de dioxabiciclo(3.3.0)octano para la preparacion de un medicamento para inhibir el metabolismo del colesterol. Expired - Lifetime ES2087252T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP28183990A JP3183664B2 (ja) 1990-10-22 1990-10-22 コレステロール及び胆汁酸の代謝阻害剤

Publications (1)

Publication Number Publication Date
ES2087252T3 true ES2087252T3 (es) 1996-07-16

Family

ID=17644733

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91309685T Expired - Lifetime ES2087252T3 (es) 1990-10-22 1991-10-21 Uso de derivados de dioxabiciclo(3.3.0)octano para la preparacion de un medicamento para inhibir el metabolismo del colesterol.

Country Status (9)

Country Link
US (1) US5270335A (es)
EP (1) EP0488513B1 (es)
JP (1) JP3183664B2 (es)
AT (1) ATE138571T1 (es)
CA (1) CA2053820C (es)
DE (1) DE69119875T2 (es)
DK (1) DK0488513T3 (es)
ES (1) ES2087252T3 (es)
GR (1) GR3020682T3 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3283274B2 (ja) * 1991-06-15 2002-05-20 サントリー株式会社 新規組成物
JPH06227977A (ja) * 1993-02-01 1994-08-16 Suntory Ltd 活性酸素消去剤
US5397778A (en) * 1994-02-25 1995-03-14 New England Deaconess Hospital Corporation Enteral formulations for treatment of inflammation and infection
AU1928295A (en) * 1994-02-25 1995-09-11 New England Deaconess Hospital Corporation Anti-inflammatory and infection protective effects of sesamin-based lignans
JP3818680B2 (ja) * 1994-05-12 2006-09-06 サントリー株式会社 アレルギー症状の予防又は改善剤
CN1073825C (zh) * 1995-07-04 2001-10-31 三得利公司 二氧杂二环[3.3.0]辛烷衍生物的新用途
JPH11246427A (ja) * 1998-03-04 1999-09-14 Kadoya Sesami Mills Inc 糖・脂質代謝活性化剤
KR100352269B1 (ko) * 1999-10-08 2002-09-12 한국생명공학연구원 저밀도 지질 단백질에 대해 항산화 활성을 갖는 리그난계 화합물
JP4388248B2 (ja) * 2001-10-29 2009-12-24 株式会社日立製作所 最適ポートフォリオ決定方法および装置
US7081260B2 (en) * 2002-10-29 2006-07-25 Council Of Scientific And Industrial Research α-Glucosidase inhibitors from a natural source
CA2603347C (en) 2005-03-31 2014-06-17 Suntory Limited Oil-in-water emulsions of lignans that exhibit improved absorption rate
JP5091680B2 (ja) 2005-09-30 2012-12-05 サントリーホールディングス株式会社 エピセサミン高含有組成物の製造方法及び装置
WO2007114013A1 (ja) 2006-03-31 2007-10-11 Suntory Limited リグナン類化合物含有組成物
ES2424167T3 (es) 2006-10-04 2013-09-27 Suntory Holdings Limited Emulsión de aceite/agua/aceite que contiene un compuesto de lignano, y composición que contiene la anterior
JP5051878B2 (ja) * 2007-03-02 2012-10-17 竹本油脂株式会社 高濃度セサミノール含有物の製造方法
EP2189160A4 (en) 2007-09-19 2010-10-13 Suntory Holdings Ltd COMPOSITION WITH A SESAMINE COMPONENT AND A VITAMIN B1 COMPONENT
CN113490422A (zh) * 2019-02-28 2021-10-08 株式会社笑颜 用于抑制/减少体重增加的组合物

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01104062A (ja) * 1987-10-16 1989-04-21 Taisho Pharmaceut Co Ltd テトラヒドロフラン誘導体
DK0409654T3 (da) * 1989-07-21 2001-12-27 Suntory Ltd Leverfunktionsforbedrende middel

Also Published As

Publication number Publication date
JPH04159221A (ja) 1992-06-02
EP0488513A3 (en) 1992-06-17
DE69119875T2 (de) 1996-10-02
EP0488513B1 (en) 1996-05-29
DK0488513T3 (da) 1996-06-17
JP3183664B2 (ja) 2001-07-09
DE69119875D1 (de) 1996-07-04
GR3020682T3 (en) 1996-10-31
EP0488513A2 (en) 1992-06-03
CA2053820A1 (en) 1992-04-23
CA2053820C (en) 1997-02-04
US5270335A (en) 1993-12-14
ATE138571T1 (de) 1996-06-15

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