LT3463B - Process for preparing pure isoflavone derivatives - Google Patents

Process for preparing pure isoflavone derivatives Download PDF

Info

Publication number
LT3463B
LT3463B LTIP779A LTIP779A LT3463B LT 3463 B LT3463 B LT 3463B LT IP779 A LTIP779 A LT IP779A LT IP779 A LTIP779 A LT IP779A LT 3463 B LT3463 B LT 3463B
Authority
LT
Lithuania
Prior art keywords
general formula
product
vii
given above
formula
Prior art date
Application number
LTIP779A
Other languages
English (en)
Lithuanian (lt)
Inventor
Tamas Kallay
Gyorgy Lanyi
Laszlo Ledniczky
Lajos Imrei
Gyorgy Hoffmann
Maria Sziladi
Eva Somfai
Tibor Montay
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of LTIP779A publication Critical patent/LTIP779A/xx
Publication of LT3463B publication Critical patent/LT3463B/lt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C07D311/26Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3
    • C07D311/34Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only
    • C07D311/36Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4 with aromatic rings attached in position 2 or 3 with aromatic rings attached in position 3 only not hydrogenated in the hetero ring, e.g. isoflavones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Train Traffic Observation, Control, And Security (AREA)
LTIP779A 1990-04-06 1993-07-13 Process for preparing pure isoflavone derivatives LT3463B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/HU1990/000023 WO1991015483A1 (en) 1990-04-06 1990-04-06 An improved process for the preparation of substituted isoflavone derivatives

Publications (2)

Publication Number Publication Date
LTIP779A LTIP779A (en) 1995-01-31
LT3463B true LT3463B (en) 1995-10-25

Family

ID=10980899

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP779A LT3463B (en) 1990-04-06 1993-07-13 Process for preparing pure isoflavone derivatives

Country Status (14)

Country Link
US (1) US5247102A (de)
EP (1) EP0478558B1 (de)
JP (1) JPH089610B2 (de)
KR (1) KR0149172B1 (de)
AT (1) ATE101143T1 (de)
AU (1) AU631860B2 (de)
CA (1) CA2058619C (de)
DE (1) DE69006502T2 (de)
DK (1) DK0478558T3 (de)
FI (1) FI915741A7 (de)
LT (1) LT3463B (de)
NO (1) NO300733B1 (de)
RU (1) RU2036918C1 (de)
WO (1) WO1991015483A1 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5002603A (en) * 1989-12-04 1991-03-26 Board Of Trustees Operating Michigan State University Method and compositions for stimulating vesicular-arbuscular mycorrhizal fungi
US5204369A (en) * 1991-07-01 1993-04-20 The Endowment For Research In Human Biology Method for the inhibition of aldh-i useful in the treatment of alcohol dependence or alcohol abuse
FR2689127B1 (fr) * 1992-03-31 1994-05-06 Adir Cie Nouvelles 3', 5' -ditertbutyl-4'-hydroxy flavones, leur procede de preparation et les compositions pharmaceutiques les renfermant.
EP1477178A3 (de) * 1992-05-19 2005-02-16 KELLY, Graham Edmund Nahrungsergänzungsmittel mit Phyto-Oestrogenen, Analogen oder Metaboliten davon
HUT68558A (en) * 1993-07-20 1995-06-28 Chinoin Gyogyszer Es Vegyeszet Method for preparing isoflavon derivatives
US5670632A (en) * 1996-01-18 1997-09-23 Acds Technologies, Ltd. Process for obtaining an isoflavone concentrate from a soybean extract
US5691275A (en) * 1996-01-29 1997-11-25 Board Of Trustees Operating Michigan State University Alkali metal formononetin and method of mycorrhizal stimulation
AUPO203996A0 (en) * 1996-08-30 1996-09-26 Novogen Research Pty Ltd Therapeutic uses
US6146668A (en) 1997-04-28 2000-11-14 Novogen, Inc. Preparation of isoflavones from legumes
US6255497B1 (en) 1997-04-29 2001-07-03 The Endowment For Research In Human Biology, Inc. Method for the inhibition of ALDH-I useful in the treatment of alcohol dependence or alcohol abuse
WO1998050026A1 (en) * 1997-05-01 1998-11-12 Novogen Inc Treatment or prevention of menopausal symptoms and osteoporosis
AUPP112497A0 (en) * 1997-12-24 1998-01-22 Novogen Research Pty Ltd Compositions and method for protecting skin from UV induced immunosupression and skin damage
IT1298619B1 (it) * 1998-03-10 2000-01-12 Erregierre Spa Processo di preparazione dell'epriflavone
AUPP260798A0 (en) * 1998-03-26 1998-04-23 Novogen Research Pty Ltd Treatment of medical related conditions with isoflavone containing extracts of clover
AUPQ266199A0 (en) * 1999-09-06 1999-09-30 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
US20090233999A1 (en) * 1999-09-06 2009-09-17 Novogen Research Pty Ltd Compositions and therapeutic methods involving isoflavones and analogues thereof
AUPQ520300A0 (en) * 2000-01-21 2000-02-17 Novogen Research Pty Ltd Food product and process
AUPR363301A0 (en) * 2001-03-08 2001-04-05 Novogen Research Pty Ltd Dimeric isoflavones
US20050119301A1 (en) * 2001-03-16 2005-06-02 Alan Husband Treatment of restenosis
US6818668B2 (en) 2002-04-12 2004-11-16 Biotest Laboratories, Llc 5-alkyl-7-alkylcarbonate-isoflavone ester and related method
KR20060011785A (ko) 2002-06-27 2006-02-03 디 인다우먼트 포 리써치 인 휴먼 바이올로지, 인크. Aldh 억제에 유용한 화합물
AU2003255232A1 (en) * 2002-08-07 2004-02-25 University Of Mississippi Antigiardial agents and use thereof
US8158810B2 (en) 2006-07-27 2012-04-17 Gilead Sciences, Inc. ALDH-2 inhibitors in the treatment of addiction
TWI365071B (en) * 2008-02-26 2012-06-01 Univ Kaohsiung Medical Isoxazole derivatives and pharmaceutical compositions comprising the same
TWI324514B (en) * 2008-02-26 2010-05-11 Univ Kaohsiung Medical Isoflavone derivatives and pharmaceutical compositions comprising the same
CN103145673B (zh) * 2011-12-06 2015-05-20 安徽贝克生物制药有限公司 黄豆苷元衍生物及其药学上可接受的盐

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA193010A (en) 1919-04-02 1919-09-30 Alvin A. Ritcheson Motor vehicle
CA201219A (en) 1920-06-22 Hippolyte Louis Sizaire Maurice Lubricating vehicle spring

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU162377B (de) * 1970-05-27 1973-02-28
GB1495305A (en) * 1975-09-12 1977-12-14 Pfizer Ltd 3-phenyl-4-oxo-4h-benzopyran derivatives
GB1495189A (en) * 1975-09-12 1977-12-14 Pfizer Ltd 4-oxo-4h-benzopyran derivatives and process for their preparation
JPS60132976A (ja) * 1983-12-21 1985-07-16 Takeda Chem Ind Ltd 新規3−フエニル−4h−1−ベンゾピラン−4−オン誘導体
US4644012A (en) * 1983-12-21 1987-02-17 Takeda Chemical Industries, Ltd. Treatment for osteoporosis
US5002603A (en) * 1989-12-04 1991-03-26 Board Of Trustees Operating Michigan State University Method and compositions for stimulating vesicular-arbuscular mycorrhizal fungi

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA201219A (en) 1920-06-22 Hippolyte Louis Sizaire Maurice Lubricating vehicle spring
CA193010A (en) 1919-04-02 1919-09-30 Alvin A. Ritcheson Motor vehicle

Also Published As

Publication number Publication date
HK1003995A1 (en) 1998-11-13
AU5427490A (en) 1991-10-30
RU2036918C1 (ru) 1995-06-09
KR920701192A (ko) 1992-08-11
CA2058619A1 (en) 1991-10-07
NO914786L (no) 1991-12-05
DE69006502D1 (de) 1994-03-17
EP0478558A1 (de) 1992-04-08
JPH04507085A (ja) 1992-12-10
NO914786D0 (no) 1991-12-05
US5247102A (en) 1993-09-21
LTIP779A (en) 1995-01-31
NO300733B1 (no) 1997-07-14
JPH089610B2 (ja) 1996-01-31
KR0149172B1 (ko) 1998-10-15
DK0478558T3 (da) 1994-05-02
FI915741A0 (fi) 1991-12-05
EP0478558B1 (de) 1994-02-02
CA2058619C (en) 1999-05-04
WO1991015483A1 (en) 1991-10-17
ATE101143T1 (de) 1994-02-15
DE69006502T2 (de) 1994-05-19
AU631860B2 (en) 1992-12-10
FI915741A7 (fi) 1991-12-05

Similar Documents

Publication Publication Date Title
LT3463B (en) Process for preparing pure isoflavone derivatives
JP3421354B2 (ja) 結晶性セフジニルアミン塩
EP0283055B1 (de) 10-Dihydro-10-deoxo-11-azaerythronolid-A-Verbindungen,Verfahren und Zwischenprodukte zu ihrer Herstellung und ihre Verwendung in Arzneimitteln und in deren Herstellung
EP1844036B1 (de) Verfahren zur Herstellung von Aripiprazol
JP3067878B2 (ja) 2−(2’,4’−ジヒドロキシフェニル)−4,6−ジアリール−s−トリアジンの製造方法
CS228520B2 (en) Method for the production of 4-hydroxy-2-methyl-n-2-pyridyl-2h-1,2-benzothiazin-3-carboxamid-1,1-dioxide
HUP0200839A2 (en) Novel synthesis and crystallization of piperazine ring-containing compounds and pharmaceutical compositions containing them
CN112272665B (zh) 制备立他司特的方法
RU2049778C1 (ru) Способ получения производного 8-хлорхинолона
KR20020041423A (ko) 나프티리딘-3-카르복실산 유도체의 제조를 위한 중간체
US6576764B2 (en) Synthesis and crystallization of piperazine ring-containing compounds
US4894457A (en) 7-bromo-beta-carboline compound and method for producing same
KR102522458B1 (ko) 날트렉손의 분리 및 정제 방법
US6610738B2 (en) N-disubstituted carbamoyloxy flavones
US4231933A (en) Novel 3-hydroxy-pyrrolin-2-one derivatives
RU2034842C1 (ru) Производные хинолина и способ их получения
HK1003995B (en) An improved process for the preparation of substituted isoflavone derivatives
US20040158077A1 (en) Process for preparation of imidazolyl compounds
EP1565445B1 (de) Verfahren zur herstellung von imidazolverbindungen
SU282173A1 (de)
Salih et al. Pyrimidines, Part XXXI. Synthesis, reactions and properties of 6‐acyl‐1, 3‐dimethylpyrrolo [2, 3‐d] pyrimidine‐2, 4‐diones
WO2012001357A1 (en) Crystalline form of prulifloxacin and processes for its preparation
HU224817B1 (en) New process for producing 17-betha-hydroxy-17-alpha-methyl-2-oxa-5-alpha-androstan-3-on and intermediate thereof
CN107098901A (zh) 具有抗惊厥活性的化合物及其制备方法和应用
HU193186B (en) Process for producing benzothiazine derivative