HRP20210011T1 - Metoda i pripravci za staničnu imunoterapiju - Google Patents

Metoda i pripravci za staničnu imunoterapiju Download PDF

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Publication number
HRP20210011T1
HRP20210011T1 HRP20210011TT HRP20210011T HRP20210011T1 HR P20210011 T1 HRP20210011 T1 HR P20210011T1 HR P20210011T T HRP20210011T T HR P20210011TT HR P20210011 T HRP20210011 T HR P20210011T HR P20210011 T1 HRP20210011 T1 HR P20210011T1
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HR
Croatia
Prior art keywords
nucleic acid
chimeric receptor
host cell
seq
cells
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Application number
HRP20210011TT
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English (en)
Croatian (hr)
Inventor
Stanley R. Riddell
Michael Hudecek
Michael Jensen
Original Assignee
Fred Hutchinson Cancer Research Center
Seattle Children's Hospital, Dba Seattle Children's Research Institute
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49054932&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HRP20210011(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fred Hutchinson Cancer Research Center, Seattle Children's Hospital, Dba Seattle Children's Research Institute filed Critical Fred Hutchinson Cancer Research Center
Publication of HRP20210011T1 publication Critical patent/HRP20210011T1/hr

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    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7151—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for tumor necrosis factor [TNF], for lymphotoxin [LT]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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    • C—CHEMISTRY; METALLURGY
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    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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    • C—CHEMISTRY; METALLURGY
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    • C07K2317/622—Single chain antibody (scFv)
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
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    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
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    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction

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HRP20210011TT 2012-08-20 2013-08-20 Metoda i pripravci za staničnu imunoterapiju HRP20210011T1 (hr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261691117P 2012-08-20 2012-08-20
EP13753495.4A EP2884999B2 (en) 2012-08-20 2013-08-20 Method and compositions for cellular immunotherapy
PCT/US2013/055862 WO2014031687A1 (en) 2012-08-20 2013-08-20 Method and compositions for cellular immunotherapy

Publications (1)

Publication Number Publication Date
HRP20210011T1 true HRP20210011T1 (hr) 2021-04-30

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Application Number Title Priority Date Filing Date
HRP20210011TT HRP20210011T1 (hr) 2012-08-20 2013-08-20 Metoda i pripravci za staničnu imunoterapiju
HRP20250397TT HRP20250397T1 (hr) 2012-08-20 2013-08-20 Postupak i sastavi za staničnu imunoterapiju

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HRP20250397TT HRP20250397T1 (hr) 2012-08-20 2013-08-20 Postupak i sastavi za staničnu imunoterapiju

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US (5) US10780118B2 (enExample)
EP (3) EP3824905B1 (enExample)
JP (4) JP6574381B2 (enExample)
KR (4) KR102135239B1 (enExample)
CN (1) CN104780939B (enExample)
AU (4) AU2013305838A1 (enExample)
BR (3) BR122020002988A8 (enExample)
CA (2) CA2881981A1 (enExample)
CY (1) CY1123959T1 (enExample)
DK (2) DK2884999T4 (enExample)
ES (2) ES3015267T3 (enExample)
FI (2) FI2884999T4 (enExample)
HR (2) HRP20210011T1 (enExample)
HU (2) HUE053439T2 (enExample)
IL (3) IL293944A (enExample)
LT (2) LT3824905T (enExample)
MX (3) MX380109B (enExample)
PH (2) PH12019550223A1 (enExample)
PL (2) PL3824905T3 (enExample)
PT (2) PT2884999T (enExample)
RS (2) RS66657B1 (enExample)
RU (2) RU2700765C2 (enExample)
SG (2) SG10201701339RA (enExample)
SI (2) SI3824905T1 (enExample)
SM (2) SMT202100005T1 (enExample)
WO (1) WO2014031687A1 (enExample)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013035099A1 (en) 2011-09-08 2013-03-14 Yeda Research And Development Co. Ltd. Anti third party central memory t cells, methods of producing same and use of same in transplantation and disease treatment
RU2746407C1 (ru) 2012-02-23 2021-04-13 Стейдж Селл Терапеутикс Гмбх Хроматографическое выделение клеток и других сложных биологических материалов
IL293944A (en) 2012-08-20 2022-08-01 Hutchinson Fred Cancer Res Method and preparations for cellular immunotherapy
EP2934532B1 (en) 2012-12-20 2019-10-23 Purdue Research Foundation Chimeric antigen receptor-expressing t cells as anti-cancer therapeutics
WO2014130657A1 (en) 2013-02-20 2014-08-28 The Trustees Of The University Of Pennsylvania Treatment of cancer using humanized anti-egfrviii chimeric antigen receptor
EP3744736A1 (en) 2013-02-20 2020-12-02 Novartis AG Effective targeting of primary human leukemia using anti-cd123 chimeric antigen receptor engineered t cells
ES2769574T3 (es) 2013-03-15 2020-06-26 Michael C Milone Reconocimiento de células citotóxicas con receptores quiméricos para inmunoterapia adoptiva
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
EP4026909A1 (en) 2013-12-19 2022-07-13 Novartis AG Human mesothelin chimeric antigen receptors and uses thereof
EP3087101B1 (en) 2013-12-20 2024-06-05 Novartis AG Regulatable chimeric antigen receptor
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