EP2085096A3
(en)
|
2002-09-11 |
2009-08-12 |
Genentech, Inc. |
Novel composition and methods for the treatment of immune related diseases
|
KR101855381B1
(ko)
|
2008-04-09 |
2018-05-09 |
제넨테크, 인크. |
면역 관련 질병의 치료를 위한 신규한 조성물 및 방법
|
US9650639B2
(en)
|
2008-05-19 |
2017-05-16 |
Advaxis, Inc. |
Dual delivery system for heterologous antigens
|
ES2741730T3
(es)
|
2008-05-19 |
2020-02-12 |
Advaxis Inc |
Sistema de administración doble para antígenos heterólogos que comprende una cepa de Listeria recombinante atenuada por la mutación de dal/dat y la deleción de ActA que comprende una molécula de ácido nucleico que codifica una proteína de fusión de listeriolisina O - antígeno prostático específico
|
US9017660B2
(en)
|
2009-11-11 |
2015-04-28 |
Advaxis, Inc. |
Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors
|
LT4209510T
(lt)
|
2008-12-09 |
2024-03-12 |
F. Hoffmann-La Roche Ag |
Anti-pd-l1 antikūnai ir jų panaudojimas t ląstelių funkcijos pagerinimui
|
US10016617B2
(en)
|
2009-11-11 |
2018-07-10 |
The Trustees Of The University Of Pennsylvania |
Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers
|
CN103282048B
(zh)
|
2010-10-01 |
2017-05-17 |
宾夕法尼亚大学理事会 |
李斯特菌疫苗载体用于在寄生虫感染的个体中扭转免疫无应答的用途
|
CN103687611A
(zh)
|
2011-03-11 |
2014-03-26 |
阿德瓦希斯公司 |
基于李斯特菌属的佐剂
|
DK2694075T3
(en)
|
2011-04-01 |
2016-08-01 |
Curis Inc |
Phosphoinositide 3-kinase inhibitor with zinc-binding moiety
|
US9945862B2
(en)
|
2011-06-03 |
2018-04-17 |
Eisai R&D Management Co., Ltd. |
Biomarkers for predicting and assessing responsiveness of thyroid and kidney cancer subjects to lenvatinib compounds
|
WO2013019906A1
(en)
|
2011-08-01 |
2013-02-07 |
Genentech, Inc. |
Methods of treating cancer using pd-1 axis binding antagonists and mek inhibitors
|
WO2013112942A1
(en)
|
2012-01-25 |
2013-08-01 |
Dna Trix, Inc. |
Biomarkers and combination therapies using oncolytic virus and immunomodulation
|
SG10201700392UA
(en)
|
2012-03-12 |
2017-03-30 |
Advaxis Inc |
Suppressor cell function inhibition following listeria vaccine treatment
|
CN112587658A
(zh)
*
|
2012-07-18 |
2021-04-02 |
博笛生物科技有限公司 |
癌症的靶向免疫治疗
|
US20150231241A1
(en)
|
2012-08-14 |
2015-08-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
US9302005B2
(en)
|
2013-03-14 |
2016-04-05 |
Mayo Foundation For Medical Education And Research |
Methods and materials for treating cancer
|
RU2015138576A
(ru)
*
|
2013-03-14 |
2017-04-19 |
Дженентек, Инк. |
Комбинации соединения ингибитора мек с соединением ингибитором her3/egfr и способы применения
|
PL2972373T3
(pl)
*
|
2013-03-15 |
2020-03-31 |
F. Hoffmann-La Roche Ag |
Biomarkery i sposoby leczenia stanów związanych z PD-1 i PD-L1
|
CN105073128A
(zh)
*
|
2013-04-03 |
2015-11-18 |
Ibc药品公司 |
用于诱导对疾病的免疫应答的组合疗法
|
US10010608B2
(en)
*
|
2013-05-31 |
2018-07-03 |
Merck Sharp & Dohme Corp. |
Combination therapies for cancer
|
CA2909052A1
(en)
|
2013-06-03 |
2014-12-11 |
Novartis Ag |
Combinations of an anti-pd-l1 antibody and a mek inhibitor and/or a braf inhibitor
|
WO2014204856A1
(en)
*
|
2013-06-17 |
2014-12-24 |
Catabasis Pharmaceuticals, Inc. |
Fatty acid anticancer derivatives and their uses
|
PT3021869T
(pt)
*
|
2013-07-16 |
2020-09-10 |
Hoffmann La Roche |
Métodos de tratamento do cancro com antagonistas da ligação ao eixo pd-1 e inibidores do tigit
|
AR097279A1
(es)
|
2013-08-09 |
2016-03-02 |
Actelion Pharmaceuticals Ltd |
Derivados de benzimidazolil-metil urea como agonistas del receptor de alx
|
CA2920113A1
(en)
*
|
2013-08-20 |
2015-02-26 |
Merck Sharp & Dohme Corp. |
Treating cancer with a combination of a pd-1 antagonist and dinaciclib
|
AR097306A1
(es)
|
2013-08-20 |
2016-03-02 |
Merck Sharp & Dohme |
Modulación de la inmunidad tumoral
|
AR097584A1
(es)
|
2013-09-12 |
2016-03-23 |
Hoffmann La Roche |
Terapia de combinación de anticuerpos contra el csf-1r humano y anticuerpos contra el pd-l1 humano
|
CN112457403B
(zh)
|
2013-09-13 |
2022-11-29 |
广州百济神州生物制药有限公司 |
抗pd1抗体及其作为治疗剂与诊断剂的用途
|
EP3757130A1
(en)
|
2013-09-26 |
2020-12-30 |
Costim Pharmaceuticals Inc. |
Methods for treating hematologic cancers
|
AR097791A1
(es)
*
|
2013-09-27 |
2016-04-13 |
Genentech Inc |
Formulaciones de anticuerpos anti-pdl1
|
US10259875B2
(en)
|
2013-10-01 |
2019-04-16 |
Mayo Foundation For Medical Education And Research |
Methods for treating cancer in patients with elevated levels of BIM
|
EP3079772B1
(en)
|
2013-12-10 |
2020-02-05 |
Merck Sharp & Dohme Corp. |
Immunohistochemical proximity assay for pd-1 positive cells and pd-ligand positive cells in tumor tissue
|
US10344090B2
(en)
|
2013-12-12 |
2019-07-09 |
Shanghai Hangrui Pharmaceutical Co., Ltd. |
PD-1 antibody, antigen-binding fragment thereof, and medical application thereof
|
US20160304969A1
(en)
|
2013-12-17 |
2016-10-20 |
Merck Sharp & Dohme Corp. |
Ifn-gamma gene signature biomarkers of tumor response to pd-1 antagonists
|
AU2014364601A1
(en)
*
|
2013-12-17 |
2016-07-07 |
Genentech, Inc. |
Methods of treating HER2-positive cancers using PD-1 axis binding antagonists and anti-HER2 antibodies
|
CA2934028A1
(en)
*
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
BR112016013741A2
(pt)
*
|
2013-12-17 |
2017-10-03 |
Genentech Inc |
Usos de antagonistas de ligação de eixo de pd-1 e um anticorpo de anti-cd20, e kit compreendendo os mesmos
|
AU2015205756A1
(en)
|
2014-01-10 |
2016-07-21 |
Birdie Biopharmaceuticals Inc. |
Compounds and compositions for treating EGFR expressing tumors
|
TWI681969B
(zh)
|
2014-01-23 |
2020-01-11 |
美商再生元醫藥公司 |
針對pd-1的人類抗體
|
TWI680138B
(zh)
|
2014-01-23 |
2019-12-21 |
美商再生元醫藥公司 |
抗pd-l1之人類抗體
|
JOP20200094A1
(ar)
|
2014-01-24 |
2017-06-16 |
Dana Farber Cancer Inst Inc |
جزيئات جسم مضاد لـ pd-1 واستخداماتها
|
JOP20200096A1
(ar)
|
2014-01-31 |
2017-06-16 |
Children’S Medical Center Corp |
جزيئات جسم مضاد لـ tim-3 واستخداماتها
|
KR20160108568A
(ko)
|
2014-02-04 |
2016-09-19 |
인사이트 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 ido1 억제제의 조합
|
US10899840B2
(en)
|
2014-02-04 |
2021-01-26 |
Pfizer Inc. |
Combination of a PD-1 antagonist and a 4-1BB agonist for treating cancer
|
SI3102605T1
(sl)
|
2014-02-04 |
2019-04-30 |
Pfizer Inc. |
Kombinacija PD-1 antagonista in VEGFR inhibitorja za zdravljenje raka
|
SG11201606577YA
(en)
|
2014-02-10 |
2016-09-29 |
Merck Patent Gmbh |
TARGETED TGFβ INHIBITION
|
BR112016018408A2
(pt)
|
2014-03-14 |
2017-12-26 |
Immutep Sas |
moléculas de anticorpo à lag-3 e usos das mesmas
|
ES2779149T3
(es)
*
|
2014-03-26 |
2020-08-13 |
Tocagen Inc |
Vector retroviral que tiene actividad inmunoestimuladora
|
RU2016142476A
(ru)
|
2014-03-31 |
2018-05-07 |
Дженентек, Инк. |
Комбинированная терапия, включающая антиангиогенезные агенты и агонисты, связывающие ох40
|
US10302653B2
(en)
|
2014-05-22 |
2019-05-28 |
Mayo Foundation For Medical Education And Research |
Distinguishing antagonistic and agonistic anti B7-H1 antibodies
|
CA2947939A1
(en)
|
2014-05-28 |
2015-12-03 |
Idenix Pharmaceuticals Llc |
Nucleoside derivatives for the treatment of cancer
|
KR101923326B1
(ko)
|
2014-06-06 |
2018-11-29 |
브리스톨-마이어스 스큅 컴퍼니 |
글루코코르티코이드-유도 종양 괴사 인자 수용체 (gitr)에 대한 항체 및 그의 용도
|
CN106604742B
(zh)
|
2014-07-03 |
2019-01-11 |
百济神州有限公司 |
抗pd-l1抗体及其作为治疗剂及诊断剂的用途
|
WO2016004876A1
(en)
|
2014-07-09 |
2016-01-14 |
Shanghai Birdie Biotech, Inc. |
Anti-pd-l1 combinations for treating tumors
|
CN105440135A
(zh)
*
|
2014-09-01 |
2016-03-30 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-pd-l1结合物
|
US20160009805A1
(en)
|
2014-07-11 |
2016-01-14 |
Genentech, Inc. |
Anti-pd-l1 antibodies and diagnostic uses thereof
|
EP3169361B1
(en)
*
|
2014-07-15 |
2019-06-19 |
F.Hoffmann-La Roche Ag |
Compositions for treating cancer using pd-1 axis binding antagonists and mek inhibitors
|
SG10201913696YA
(en)
|
2014-07-18 |
2020-03-30 |
Advaxis Inc |
Combination of a pd-1 antagonist and a listeria-based vaccine for treating prostate cancer
|
KR102524920B1
(ko)
|
2014-07-22 |
2023-04-25 |
아폴로믹스 인코포레이티드 |
항-pd-1 항체
|
US10517875B2
(en)
|
2014-07-23 |
2019-12-31 |
Mayo Foundation for Medical Engineering and Research |
Targeting DNA-PKcs and B7-H1 to treat cancer
|
US9982052B2
(en)
|
2014-08-05 |
2018-05-29 |
MabQuest, SA |
Immunological reagents
|
AU2015298356B2
(en)
|
2014-08-05 |
2020-11-19 |
MabQuest SA |
Immunological reagents binding to pd-1
|
JP6909153B2
(ja)
|
2014-08-05 |
2021-07-28 |
アポロミクス インコーポレイテッド |
抗pd−l1抗体
|
EP3177640B1
(en)
*
|
2014-08-08 |
2020-05-06 |
The Board of Trustees of the Leland Stanford Junior University |
High affinity pd-1 agents and methods of use
|
CN106573981A
(zh)
|
2014-08-12 |
2017-04-19 |
鳄鱼生物科学公司 |
利用抗cd40抗体的组合疗法
|
KR20170035945A
(ko)
*
|
2014-08-14 |
2017-03-31 |
에프. 호프만-라 로슈 아게 |
인간 cd40을 활성화시키는 항체 및 인간 pd-l1에 대한 항체의 병용 요법
|
EP3070102A1
(en)
*
|
2015-03-18 |
2016-09-21 |
F. Hoffmann-La Roche AG |
Combination therapy of antibodies human cd40 activating antibodies and anti human pld-1 antibodies
|
JP2017530950A
(ja)
|
2014-08-25 |
2017-10-19 |
ファイザー・インコーポレイテッド |
癌を処置するためのpd−1アンタゴニストおよびalk阻害剤の併用
|
MX2017001980A
(es)
|
2014-08-28 |
2017-05-04 |
Eisai R&D Man Co Ltd |
Derivado de quinolina muy puro y metodo para su produccion.
|
EP3186281B1
(en)
|
2014-08-28 |
2019-04-10 |
Halozyme, Inc. |
Combination therapy with a hyaluronan-degrading enzyme and an immune checkpoint inhibitor
|
US9535074B2
(en)
|
2014-09-08 |
2017-01-03 |
Merck Sharp & Dohme Corp. |
Immunoassay for soluble PD-L1
|
WO2016040882A1
(en)
*
|
2014-09-13 |
2016-03-17 |
Novartis Ag |
Combination therapies of egfr inhibitors
|
JP2017534577A
(ja)
*
|
2014-09-15 |
2017-11-24 |
ジェネンテック, インコーポレイテッド |
Pd−1軸結合拮抗薬及びil−17結合拮抗薬を使用したがんの治療方法
|
DK3193931T3
(da)
|
2014-09-16 |
2020-10-19 |
Innate Pharma |
Neutralisering af hæmmende veje i lymfocytter
|
EP3662903A3
(en)
|
2014-10-03 |
2020-10-14 |
Novartis AG |
Combination therapies
|
ES2821964T3
(es)
|
2014-10-10 |
2021-04-28 |
Innate Pharma |
Bloqueo de CD73
|
CN115040532A
(zh)
|
2014-10-10 |
2022-09-13 |
伊黛拉制药有限公司 |
使用tlr9激动剂与检查点抑制剂对癌症的治疗
|
CA2964317C
(en)
|
2014-10-14 |
2021-10-05 |
Halozyme, Inc. |
Compositions of adenosine deaminase-2 (ada2), variants thereof and methods of using same
|
SG11201702401RA
(en)
|
2014-10-14 |
2017-04-27 |
Novartis Ag |
Antibody molecules to pd-l1 and uses thereof
|
BR112017010198A2
(pt)
*
|
2014-11-17 |
2017-12-26 |
Genentech Inc |
terapia de combinação compreendendo agonistas de ligação a ox40 e antagonistas de ligação ao eixo de pd-1
|
EP4141032A1
(en)
*
|
2014-11-20 |
2023-03-01 |
F. Hoffmann-La Roche AG |
Combination therapy of t cell activating bispecific antigen binding molecules and pd-1 axis binding antagonists
|
CN105669862A
(zh)
*
|
2014-11-21 |
2016-06-15 |
上海中信国健药业股份有限公司 |
抗人pd-l1/kir双特异性抗体及其制备方法和应用
|
KR20170101925A
(ko)
*
|
2014-12-02 |
2017-09-06 |
셀진 코포레이션 |
병용 요법
|
WO2016089797A1
(en)
|
2014-12-05 |
2016-06-09 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
EP3226689B1
(en)
|
2014-12-05 |
2020-01-15 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
CN107206088A
(zh)
*
|
2014-12-05 |
2017-09-26 |
豪夫迈·罗氏有限公司 |
使用pd‑1轴拮抗剂和hpk1拮抗剂用于治疗癌症的方法和组合物
|
EP3226690B1
(en)
|
2014-12-05 |
2020-05-20 |
Merck Sharp & Dohme Corp. |
Novel tricyclic compounds as inhibitors of mutant idh enzymes
|
WO2016094377A1
(en)
|
2014-12-09 |
2016-06-16 |
Merck Sharp & Dohme Corp. |
System and methods for deriving gene signature biomarkers of response to pd-1 antagonists
|
WO2016100882A1
(en)
|
2014-12-19 |
2016-06-23 |
Novartis Ag |
Combination therapies
|
US20170363614A1
(en)
*
|
2014-12-22 |
2017-12-21 |
Enumeral Biomedical Holdings, Inc. |
Methods For Screening Therapeutic Compounds
|
WO2016109546A2
(en)
*
|
2014-12-30 |
2016-07-07 |
Genentech, Inc. |
Methods and compositions for prognosis and treatment of cancers
|
JP2016155776A
(ja)
*
|
2015-02-24 |
2016-09-01 |
学校法人兵庫医科大学 |
抗腫瘍効果増強剤および抗腫瘍剤
|
SG11201706630UA
(en)
|
2015-02-25 |
2017-09-28 |
Eisai R&D Man Co Ltd |
Method for suppressing bitterness of quinoline derivative
|
KR20170132171A
(ko)
|
2015-02-26 |
2017-12-01 |
메르크 파텐트 게엠베하 |
암 치료를 위한 pd1 / pdl1 저해제
|
AU2015384801B2
(en)
|
2015-03-04 |
2022-01-06 |
Eisai R&D Management Co., Ltd. |
Combination of a PD-1 antagonist and a VEGFR/FGFR/RET tyrosine kinase inhibitor for treating cancer
|
EP3265122B1
(en)
|
2015-03-04 |
2022-05-04 |
Merck Sharp & Dohme Corp. |
Combination of pembrolizumab and eribulin for treating triple-negative breast cancer
|
IL292449B2
(en)
|
2015-03-13 |
2024-02-01 |
Cytomx Therapeutics Inc |
Nucleic acids encoding antibodies against PDL1 and methods for their preparation
|
US10478494B2
(en)
|
2015-04-03 |
2019-11-19 |
Astex Therapeutics Ltd |
FGFR/PD-1 combination therapy for the treatment of cancer
|
EP3283882B1
(en)
|
2015-04-17 |
2020-12-16 |
Merck Sharp & Dohme Corp. |
Blood-based biomarkers of tumor sensitivity to pd-1 antagonists
|
US10702526B2
(en)
*
|
2015-04-20 |
2020-07-07 |
Effector Therapeutics Inc. |
Inhibitors of immune checkpoint modulators and related methods
|
WO2016179576A1
(en)
*
|
2015-05-07 |
2016-11-10 |
Bioxcel Corporation |
Novel immunomodulatory therapeutic strategies targeting tumors in cancer
|
US10881733B2
(en)
*
|
2015-05-22 |
2021-01-05 |
Translational Drug Development, Llc |
Benzamide and active compound compositions and methods of use
|
WO2016189055A1
(en)
|
2015-05-27 |
2016-12-01 |
Idenix Pharmaceuticals Llc |
Nucleotides for the treatment of cancer
|
KR20180014009A
(ko)
|
2015-05-29 |
2018-02-07 |
머크 샤프 앤드 돔 코포레이션 |
암을 치료하기 위한 pd-1 길항제 및 cpg-c 유형 올리고뉴클레오티드의 조합
|
AR105618A1
(es)
*
|
2015-05-29 |
2017-10-25 |
Genentech Inc |
Metilación del promotor del ligando al receptor de muerte programada (pd-l1) en cáncer
|
US20180258143A1
(en)
|
2015-05-30 |
2018-09-13 |
Molecular Templates, Inc. |
De-Immunized, Shiga Toxin A Subunit Scaffolds and Cell-Targeting Molecules Comprising the Same
|
WO2016196218A1
(en)
*
|
2015-05-31 |
2016-12-08 |
Curegenix Corporation |
Combination compositions for immunotherapy
|
JP6996983B2
(ja)
*
|
2015-06-16 |
2022-02-21 |
ジェネンテック, インコーポレイテッド |
抗cll-1抗体及び使用方法
|
KR20180018762A
(ko)
|
2015-06-16 |
2018-02-21 |
메르크 파텐트 게엠베하 |
Pd-l1 길항제 조합 치료
|
MX2017015896A
(es)
|
2015-06-16 |
2018-08-09 |
Eisai R&D Man Co Ltd |
Agente anticancerigeno.
|
WO2016205320A1
(en)
*
|
2015-06-17 |
2016-12-22 |
Genentech, Inc. |
Methods of treating locally advanced or metastatic breast cancers using pd-1 axis binding antagonists and taxanes
|
GB201511790D0
(en)
|
2015-07-06 |
2015-08-19 |
Iomet Pharma Ltd |
Pharmaceutical compound
|
CN114591433A
(zh)
|
2015-07-13 |
2022-06-07 |
西托姆克斯治疗公司 |
抗pd-1抗体、可活化抗pd-1抗体及其使用方法
|
CN108027373B
(zh)
*
|
2015-07-13 |
2021-04-09 |
佰欧迪塞克斯公司 |
受益于阻断t细胞程序性细胞死亡1(pd-1)检查点蛋白的配体活化的抗体药物的黑素瘤患者的预测性测试和分类器开发方法
|
US10786547B2
(en)
|
2015-07-16 |
2020-09-29 |
Biokine Therapeutics Ltd. |
Compositions, articles of manufacture and methods for treating cancer
|
BR112018000917A2
(pt)
|
2015-07-16 |
2018-09-11 |
Bioxcel Therapeutics Inc |
abordagem inovadora para o tratamento de câncer através da imunomodulação
|
US20180207273A1
(en)
|
2015-07-29 |
2018-07-26 |
Novartis Ag |
Combination therapies comprising antibody molecules to tim-3
|
EP3964528A1
(en)
|
2015-07-29 |
2022-03-09 |
Novartis AG |
Combination therapies comprising antibody molecules to lag-3
|
WO2017024465A1
(en)
*
|
2015-08-10 |
2017-02-16 |
Innovent Biologics (Suzhou) Co., Ltd. |
Pd-1 antibodies
|
WO2017027645A1
(en)
|
2015-08-13 |
2017-02-16 |
Merck Sharp & Dohme Corp. |
Cyclic di-nucleotide compounds as sting agonists
|
US11453697B1
(en)
|
2015-08-13 |
2022-09-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
WO2017040990A1
(en)
|
2015-09-03 |
2017-03-09 |
Aileron Therapeutics, Inc. |
Peptidomimetic macrocycles and uses thereof
|
TWI747841B
(zh)
|
2015-09-25 |
2021-12-01 |
美商建南德克公司 |
抗tigit抗體及使用方法
|
AR106188A1
(es)
|
2015-10-01 |
2017-12-20 |
Hoffmann La Roche |
Anticuerpos anti-cd19 humano humanizados y métodos de utilización
|
CA2992863A1
(en)
|
2015-10-02 |
2017-04-06 |
F. Hoffmann-La Roche Ag |
Bispecific antibodies specific for a costimulatory tnf receptor
|
AU2016334041B2
(en)
*
|
2015-10-08 |
2023-02-09 |
Macrogenics, Inc. |
Combination therapy for the treatment of cancer
|
WO2017064043A1
(en)
|
2015-10-12 |
2017-04-20 |
Innate Pharma |
Cd73 blocking agents
|
US10875923B2
(en)
|
2015-10-30 |
2020-12-29 |
Mayo Foundation For Medical Education And Research |
Antibodies to B7-H1
|
PE20181300A1
(es)
|
2015-11-02 |
2018-08-09 |
Five Prime Therapeutics Inc |
Polipeptidos del dominio extracelular de cd80 y su uso en el tratamiento del cancer
|
EP3370769A4
(en)
|
2015-11-03 |
2019-05-22 |
Janssen Biotech, Inc. |
SPECIFIC TO TIM-3 BINDING ANTIBODIES AND THEIR USE
|
RU2020113165A
(ru)
|
2015-12-03 |
2020-06-09 |
Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед |
Циклические пуриновые динуклеотиды в качестве модуляторов sting
|
WO2017098421A1
(en)
|
2015-12-08 |
2017-06-15 |
Glaxosmithkline Intellectual Property Development Limited |
Benzothiadiazine compounds
|
EP3389783A4
(en)
|
2015-12-15 |
2019-05-15 |
Merck Sharp & Dohme Corp. |
NOVEL COMPOUNDS THAN INDOLAMINE-2,3-DIOXYGENASE INHIBITORS
|
GB201522309D0
(en)
|
2015-12-17 |
2016-02-03 |
Photocure Asa |
Use
|
CN108495651A
(zh)
|
2015-12-17 |
2018-09-04 |
诺华股份有限公司 |
抗pd-1的抗体分子及其用途
|
GB201522311D0
(en)
|
2015-12-17 |
2016-02-03 |
Photocure Asa |
Use
|
CN106943598A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-her2组合
|
CN115554406A
(zh)
|
2016-01-07 |
2023-01-03 |
博笛生物科技有限公司 |
用于治疗肿瘤的抗-cd20组合
|
CN106943597A
(zh)
|
2016-01-07 |
2017-07-14 |
博笛生物科技(北京)有限公司 |
用于治疗肿瘤的抗-egfr组合
|
US10596257B2
(en)
*
|
2016-01-08 |
2020-03-24 |
Hoffmann-La Roche Inc. |
Methods of treating CEA-positive cancers using PD-1 axis binding antagonists and anti-CEA/anti-CD3 bispecific antibodies
|
CA3012055A1
(en)
|
2016-01-21 |
2017-07-27 |
Innate Pharma |
Neutralization of inhibitory pathways in lymphocytes
|
EP3405497A2
(en)
|
2016-01-22 |
2018-11-28 |
Mabquest SA |
Immunological reagents
|
US11214617B2
(en)
|
2016-01-22 |
2022-01-04 |
MabQuest SA |
Immunological reagents
|
WO2017136139A1
(en)
|
2016-02-01 |
2017-08-10 |
Biodesix, Inc. |
Predictive test for melanoma patient benefit from interleukin-2 (il2) therapy
|
KR102398425B1
(ko)
|
2016-03-08 |
2022-05-16 |
이나뜨 파르마 에스.에이. |
Siglec 중화 항체
|
WO2017153952A1
(en)
|
2016-03-10 |
2017-09-14 |
Glaxosmithkline Intellectual Property Development Limited |
5-sulfamoyl-2-hydroxybenzamide derivatives
|
WO2017160599A1
(en)
|
2016-03-14 |
2017-09-21 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Use of cd300b antagonists to treat sepsis and septic shock
|
CA3016474A1
(en)
|
2016-03-15 |
2017-09-21 |
Mersana Therapeutics, Inc. |
Napi2b-targeted antibody-drug conjugates and methods of use thereof
|
CA3016552A1
(en)
*
|
2016-03-15 |
2017-09-21 |
Genentech, Inc. |
Methods of treating cancers using pd-1 axis binding antagonists and anti-gpc3 antibodies
|
TW201735949A
(zh)
|
2016-03-24 |
2017-10-16 |
千禧製藥公司 |
治療抗ctla4及抗pd-1組合治療中的胃腸道免疫相關不良事件之方法
|
EP3433275A1
(en)
|
2016-03-24 |
2019-01-30 |
Millennium Pharmaceuticals, Inc. |
Methods of treating gastrointestinal immune-related adverse events in immune oncology treatments
|
WO2017167921A1
(en)
|
2016-03-30 |
2017-10-05 |
Centre Léon-Bérard |
Lymphocytes expressing cd73 in cancerous patient dictates therapy
|
MY189100A
(en)
|
2016-04-07 |
2022-01-25 |
Glaxosmithkline Ip Dev Ltd |
Heterocyclic amides useful as protein modulators
|
JP2019510802A
(ja)
|
2016-04-07 |
2019-04-18 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
タンパク質調節物質として有用な複素環アミド
|
KR102418766B1
(ko)
|
2016-04-12 |
2022-07-08 |
일라이 릴리 앤드 캄파니 |
암 치료에 사용하기 위한 Notch 및 PI3K/mTOR 억제제의 조합 요법
|
CN109154027A
(zh)
|
2016-04-15 |
2019-01-04 |
豪夫迈·罗氏有限公司 |
用于监测和治疗癌症的方法
|
US20200325234A1
(en)
*
|
2016-04-27 |
2020-10-15 |
Miradx |
Immune-based treatment of kras-variant cancer patients
|
US20190298824A1
(en)
|
2016-05-04 |
2019-10-03 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Serv |
Albumin-binding immunomodulatory compositions and methods of use thereof
|
WO2017191545A1
(en)
|
2016-05-05 |
2017-11-09 |
Glaxosmithkline Intellectual Property (No.2) Limited |
Enhancer of zeste homolog 2 inhibitors
|
TWI822521B
(zh)
|
2016-05-13 |
2023-11-11 |
美商再生元醫藥公司 |
藉由投予pd-1抑制劑治療皮膚癌之方法
|
ES2904880T3
(es)
|
2016-05-20 |
2022-04-06 |
Lilly Co Eli |
Terapia combinada con inhibidores de Notch y de PD-1 o PD-L1
|
US10851053B2
(en)
|
2016-06-08 |
2020-12-01 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
CA3026982A1
(en)
|
2016-06-08 |
2017-12-14 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as atf4 pathway inhibitors
|
JP6993056B2
(ja)
|
2016-07-05 |
2022-02-15 |
ベイジーン リミテッド |
癌治療のためのpd-1アンタゴニスト及びraf阻害剤の組合せ
|
WO2018014260A1
(en)
|
2016-07-20 |
2018-01-25 |
Nanjing Legend Biotech Co., Ltd. |
Multispecific antigen binding proteins and methods of use thereof
|
JP2019521166A
(ja)
|
2016-07-20 |
2019-07-25 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
Perk阻害剤としてのイソキノリン誘導体
|
CN109476748B
(zh)
*
|
2016-08-08 |
2023-05-23 |
豪夫迈·罗氏有限公司 |
用于癌症的治疗和诊断方法
|
CN110087680B
(zh)
|
2016-08-19 |
2024-03-19 |
百济神州有限公司 |
使用包含btk抑制剂的组合产品治疗癌症
|
EP3504239A1
(en)
|
2016-08-25 |
2019-07-03 |
H. Hoffnabb-La Roche Ag |
Intermittent dosing of an anti-csf-1r antibody in combination with macrophage activating agent
|
BR112019005815A2
(pt)
*
|
2016-09-29 |
2019-06-25 |
Genentech Inc |
métodos de tratamento de um indivíduo com câncer de mama, kit para o tratamento de câncer de mama e combinação de fármacos para terapia de câncer de mama
|
UA125223C2
(uk)
|
2016-10-04 |
2022-02-02 |
Мерк Шарп І Доум Корп. |
СПОЛУКИ БЕНЗО[b]ТІОФЕНУ ЯК АГОНІСТИ STING
|
US11274154B2
(en)
|
2016-10-06 |
2022-03-15 |
Pfizer Inc. |
Dosing regimen of avelumab for the treatment of cancer
|
WO2018068201A1
(en)
*
|
2016-10-11 |
2018-04-19 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against ctla-4
|
JP2019530706A
(ja)
|
2016-10-14 |
2019-10-24 |
メルク・シャープ・アンド・ドーム・コーポレーションMerck Sharp & Dohme Corp. |
尿路上皮がんを治療するための、pd−1アンタゴニスト及びエリブリンの組合せ
|
EP3535295A1
(en)
|
2016-11-02 |
2019-09-11 |
EngMab Sàrl |
Bispecific antibody against bcma and cd3 and an immunological drug for combined use in treating multiple myeloma
|
WO2018089293A2
(en)
|
2016-11-08 |
2018-05-17 |
Qilu Puget Sound Biotherapeutics Corporation |
Anti-pd1 and anti-ctla4 antibodies
|
WO2018091542A1
(en)
|
2016-11-21 |
2018-05-24 |
Idenix Pharmaceuticals Llc |
Cyclic phosphate substituted nucleoside derivatives for the treatment of liver diseases
|
US11135307B2
(en)
|
2016-11-23 |
2021-10-05 |
Mersana Therapeutics, Inc. |
Peptide-containing linkers for antibody-drug conjugates
|
MX2019006072A
(es)
|
2016-11-30 |
2019-08-14 |
Oncomed Pharm Inc |
Metodos para tratamiento de cancer que comprenden agentes de enlace al inmunoreceptor de celulas t con dominios ige itim (tigit).
|
EP3548069A1
(en)
|
2016-12-01 |
2019-10-09 |
GlaxoSmithKline Intellectual Property Development Limited |
Combination therapy
|
KR20190090823A
(ko)
|
2016-12-01 |
2019-08-02 |
글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 |
조합 요법
|
MX2019006331A
(es)
*
|
2016-12-12 |
2019-07-12 |
Genentech Inc |
Métodos para tratar el cáncer usando anticuerpos anti-pd-l1 y antiandrógenos.
|
CN110072553B
(zh)
|
2016-12-22 |
2023-09-15 |
豪夫迈·罗氏有限公司 |
在抗pd-l1/pd1治疗失败之后抗csf-1r抗体与抗pd-l1抗体组合对肿瘤的治疗
|
CN108239149B
(zh)
*
|
2016-12-25 |
2021-03-05 |
南京传奇生物科技有限公司 |
高亲和力、高特异性、多抗原识别表位的具有更高功能性的抗人pd-l1抗体
|
US20190315852A1
(en)
|
2017-01-05 |
2019-10-17 |
Netris Pharma |
Combined treatment with netrin-1 interfering drug and immune checkpoint inhibitors drugs
|
CN110383069A
(zh)
|
2017-01-05 |
2019-10-25 |
佰欧迪塞克斯公司 |
用于鉴定总体不良预后亚组中持久受益于免疫疗法的癌症患者的方法
|
WO2018137681A1
(en)
|
2017-01-25 |
2018-08-02 |
Beigene, Ltd. |
Crystalline forms of (s) -7- (1- (but-2-ynoyl) piperidin-4-yl) -2- (4-phenoxyphenyl) -4, 5, 6, 7-tetrahy dropyrazolo [1, 5-a] pyrimidine-3-carboxamide, preparation, and uses thereof
|
EP3573718B1
(en)
|
2017-01-27 |
2022-06-01 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
ES2891326T3
(es)
|
2017-01-27 |
2022-01-27 |
Janssen Biotech Inc |
Dinucleótidos cíclicos como agonistas de la STING
|
WO2018141959A1
(en)
|
2017-02-06 |
2018-08-09 |
Innate Pharma |
Immunomodulatory antibody drug conjugates binding to a human mica polypeptide
|
MA47604A
(fr)
|
2017-02-21 |
2020-01-01 |
Regeneron Pharma |
Anticorps anti-pd-1 pour le traitement du cancer du poumon
|
CN108503691B
(zh)
*
|
2017-02-25 |
2021-07-23 |
复旦大学 |
一种人pd-l1蛋白高亲和性肽及其应用
|
CN110573504A
(zh)
|
2017-02-27 |
2019-12-13 |
葛兰素史克知识产权开发有限公司 |
作为激酶抑制剂的杂环酰胺
|
WO2018160538A1
(en)
|
2017-02-28 |
2018-09-07 |
Mersana Therapeutics, Inc. |
Combination therapies of her2-targeted antibody-drug conjugates
|
WO2018167778A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of diagnosing and prognosing cancer
|
WO2018167780A1
(en)
|
2017-03-12 |
2018-09-20 |
Yeda Research And Development Co. Ltd. |
Methods of prognosing and treating cancer
|
KR102584011B1
(ko)
|
2017-03-16 |
2023-09-27 |
이나뜨 파르마 에스.에이. |
암 치료를 위한 조성물 및 방법
|
JP7166278B2
(ja)
|
2017-03-30 |
2022-11-07 |
メルク パテント ゲゼルシャフト ミット ベシュレンクテル ハフツング |
がんの治療のための抗pd-l1抗体およびdna-pkインヒビターの併用
|
US11603407B2
(en)
|
2017-04-06 |
2023-03-14 |
Regeneron Pharmaceuticals, Inc. |
Stable antibody formulation
|
CN108794467A
(zh)
|
2017-04-27 |
2018-11-13 |
博笛生物科技有限公司 |
2-氨基-喹啉衍生物
|
JP2020517913A
(ja)
|
2017-04-28 |
2020-06-18 |
ファイブ プライム セラピューティクス, インコーポレイテッド |
Cd80細胞外ドメインポリペプチドによる治療方法
|
US11466047B2
(en)
|
2017-05-12 |
2022-10-11 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
KR20200006115A
(ko)
|
2017-05-16 |
2020-01-17 |
브리스톨-마이어스 스큅 컴퍼니 |
항-gitr 효능제 항체에 의한 암의 치료
|
BR112019025188A2
(pt)
|
2017-06-01 |
2020-06-23 |
Cytomx Therapeutics, Inc. |
Anticorpos anti-pdl1 ativáveis e métodos de uso dos mesmos
|
WO2018225093A1
(en)
|
2017-06-07 |
2018-12-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds as atf4 pathway inhibitors
|
BR112019025325A2
(pt)
|
2017-06-09 |
2020-06-23 |
Glaxosmithkline Intellectual Property Development Limited |
Métodos para tratar câncer, para fabricar um anticorpo anti-icos ou porção de ligação a antígeno do mesmo, para fabricar um anticorpo anti-pd1 ou porção de ligação a antígeno do mesmo, para fabricar um anticorpo anti-pdl1 ou porção de ligação a antígeno do mesmo, anticorpo anti-icos ou fragmento de ligação a antígeno do mesmo e um anticorpo anti-pd1 ou fragmento de ligação a antígeno do mesmo, anticorpo anti-icos ou fragmento de ligação a antígeno do mesmo e um anticorpo anti-pd-l1 ou fragmento de ligação a antígeno do mesmo, uso de um anticorpo anti-icos ou porção de ligação a antígeno do mesmo e um anticorpo anti-pd1 ou porção de ligação a antígeno do mesmo, polinucleotídeo, vetor, e, célula hospedeira
|
JP2020523018A
(ja)
|
2017-06-09 |
2020-08-06 |
プロビデンス ヘルス アンド サービシーズ−オレゴン |
がんの処置のための腫瘍反応性ヒトt細胞の同定のためのcd39およびcd103の使用
|
BR112019027025A2
(pt)
|
2017-06-23 |
2020-06-30 |
Birdie Biopharmaceuticals, Inc. |
composições farmacêuticas
|
EP3645569A4
(en)
|
2017-06-26 |
2021-03-24 |
BeiGene, Ltd. |
IMMUNOTHERAPY FOR LIVER CELL CARCINOMA
|
US20210145771A1
(en)
|
2017-07-03 |
2021-05-20 |
Glaxosmithkline Intellectual Property Development Limited |
N-(3-(2-(4-chlorophenoxy)acetamido)bicyclo[1.1.1] pentan-1-yl)-2-cyclobutane-1- carboxamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases
|
US20200140383A1
(en)
|
2017-07-03 |
2020-05-07 |
Glaxosmithkline Intellectual Property Development Limited |
2-(4-chlorophenoxy)-n-((1 -(2-(4-chlorophenoxy)ethynazetidin-3-yl)methyl)acetamide derivatives and related compounds as atf4 inhibitors for treating cancer and other diseases
|
CA3066514A1
(en)
|
2017-07-10 |
2019-01-17 |
Innate Pharma |
Siglec-9-neutralizing antibodies
|
EP3655542A1
(en)
|
2017-07-18 |
2020-05-27 |
Institut Gustave Roussy |
Method for assessing the response to pd-1/pdl-1 targeting drugs
|
WO2019021208A1
(en)
|
2017-07-27 |
2019-01-31 |
Glaxosmithkline Intellectual Property Development Limited |
USEFUL INDAZOLE DERIVATIVES AS PERK INHIBITORS
|
RU2020109328A
(ru)
|
2017-08-04 |
2021-09-06 |
Мерк Шарп И Доум Корп. |
Комбинации антагонистов pd-1 и бензо[b]тиофеновых агонистов sting для лечения рака
|
US11285131B2
(en)
|
2017-08-04 |
2022-03-29 |
Merck Sharp & Dohme Corp. |
Benzo[b]thiophene STING agonists for cancer treatment
|
TW201922721A
(zh)
|
2017-09-07 |
2019-06-16 |
英商葛蘭素史克智慧財產發展有限公司 |
化學化合物
|
WO2019053617A1
(en)
|
2017-09-12 |
2019-03-21 |
Glaxosmithkline Intellectual Property Development Limited |
CHEMICAL COMPOUNDS
|
US11377440B2
(en)
|
2017-10-05 |
2022-07-05 |
Glaxosmithkline Intellectual Property Development Limited |
Modulators of stimulator of interferon genes (STING)
|
EP3692033A1
(en)
|
2017-10-05 |
2020-08-12 |
GlaxoSmithKline Intellectual Property Development Limited |
Modulators of stimulator of interferon genes (sting) useful in treating hiv
|
JP7274469B2
(ja)
|
2017-10-06 |
2023-05-16 |
イナート・ファルマ・ソシエテ・アノニム |
Cd39/cd73軸によるt細胞活性の回復
|
CN109663130B
(zh)
*
|
2017-10-13 |
2021-06-29 |
江苏恒瑞医药股份有限公司 |
Pd-1抗体和mek抑制剂联合在制备治疗肿瘤的药物中的用途
|
BR112020007046A2
(pt)
|
2017-10-19 |
2020-11-17 |
Debiopharm International S.A. |
produto de combinação para o tratamento do câncer
|
US20210179607A1
(en)
|
2017-11-01 |
2021-06-17 |
Merck Sharp & Dohme Corp. |
Novel substituted tetrahydroquinolin compounds as indoleamine 2,3-dioxygenase (ido) inhibitors
|
ES2948307T3
(es)
|
2017-11-14 |
2023-09-08 |
Merck Sharp & Dohme Llc |
Nuevos compuestos de biarilo sustituidos como inhibidores de indolamina 2,3-dioxigenasa (IDO)
|
US11498904B2
(en)
|
2017-11-14 |
2022-11-15 |
Merck Sharp & Dohme Llc |
Substituted biaryl compounds as indoleamine 2,3-dioxygenase (IDO) inhibitors
|
JP2021503478A
(ja)
|
2017-11-16 |
2021-02-12 |
ノバルティス アーゲー |
組み合わせ治療
|
WO2019104289A1
(en)
|
2017-11-27 |
2019-05-31 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
CN111801334B
(zh)
|
2017-11-29 |
2023-06-09 |
百济神州瑞士有限责任公司 |
使用包含btk抑制剂的组合治疗惰性或侵袭性b-细胞淋巴瘤
|
CN108165536A
(zh)
*
|
2017-12-11 |
2018-06-15 |
浙江大学 |
一种重组溶瘤痘苗病毒及其制备方法与应用
|
WO2019118839A1
(en)
|
2017-12-15 |
2019-06-20 |
Janssen Biotech, Inc. |
Cyclic dinucleotides as sting agonists
|
US11685761B2
(en)
|
2017-12-20 |
2023-06-27 |
Merck Sharp & Dohme Llc |
Cyclic di-nucleotide compounds as sting agonists
|
US20220305127A1
(en)
|
2017-12-21 |
2022-09-29 |
Mersana Therapeutics, Inc. |
Pyrrolobenzodiazepine antibody conjugates
|
EP3732202A4
(en)
|
2017-12-28 |
2022-06-15 |
Nanjing Legend Biotech Co., Ltd. |
SINGLE DOMAIN ANTIBODIES AND VARIANTS THEREOF AGAINST TIGIT
|
JP2021516215A
(ja)
*
|
2018-01-10 |
2021-07-01 |
アレイ・バイオファーマ・インコーポレーテッド |
癌を処置するための方法および併用療法
|
CA3084518A1
(en)
|
2018-01-15 |
2019-07-18 |
Nanjing Legend Biotech Co., Ltd. |
Single-domain antibodies and variants thereof against pd-1
|
MA54118A
(fr)
|
2018-01-31 |
2021-09-15 |
Celgene Corp |
Polythérapie utilisant une thérapie cellulaire adoptive et un inhibiteur de point de contrôle
|
US20210353614A1
(en)
|
2018-03-14 |
2021-11-18 |
Merck Patent Gmbh |
Compounds and uses thereof to treat tumors in a subject
|
EP3774765A4
(en)
|
2018-04-03 |
2021-12-29 |
Merck Sharp & Dohme Corp. |
Aza-benzothiophene compounds as sting agonists
|
CA3095646A1
(en)
|
2018-04-03 |
2019-10-10 |
Merck Sharp & Dohme Corp. |
Benzothiophenes and related compounds as sting agonists
|
WO2019193540A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Heteroaryl derivatives of formula (i) as atf4 inhibitors
|
WO2019193541A1
(en)
|
2018-04-06 |
2019-10-10 |
Glaxosmithkline Intellectual Property Development Limited |
Bicyclic aromatic ring derivatives of formula (i) as atf4 inhibitors
|
WO2019204179A1
(en)
|
2018-04-20 |
2019-10-24 |
Merck Sharp & Dohme Corp. |
Novel substituted rig-i agonists: compositions and methods thereof
|
AU2019264229A1
(en)
|
2018-05-04 |
2020-12-03 |
Merck Patent Gmbh |
Combined inhibition of PD-1/PD-L1, TGFβ and DNA-PK for the treatment of cancer
|
AU2019264232A1
(en)
|
2018-05-04 |
2020-11-12 |
Tollys |
TLR3 ligands that activate both epithelial and myeloid cells
|
BR112020022265A2
(pt)
*
|
2018-05-07 |
2021-02-23 |
Genmab A/S |
método para tratar câncer em um indivíduo, e, estojo.
|
GB201807924D0
(en)
|
2018-05-16 |
2018-06-27 |
Ctxt Pty Ltd |
Compounds
|
EA202092839A1
(ru)
|
2018-05-24 |
2021-02-12 |
Янссен Байотек, Инк. |
Агенты, связывающиеся с psma, и виды их применения
|
WO2019231870A1
(en)
|
2018-05-31 |
2019-12-05 |
Merck Sharp & Dohme Corp. |
Novel substituted [1.1.1] bicyclo compounds as indoleamine 2,3-dioxygenase inhibitors
|
US20210253614A1
(en)
|
2018-05-31 |
2021-08-19 |
Peloton Therapeutics, Inc. |
Compositions and methods for inhibiting cd73
|
CN112566938A
(zh)
|
2018-06-03 |
2021-03-26 |
拉姆卡普生物测试有限公司 |
针对ceacam5和cd47的双特异性抗体
|
WO2019242505A1
(zh)
|
2018-06-17 |
2019-12-26 |
上海健信生物医药科技有限公司 |
靶向cldn18.2的抗体、双特异性抗体、adc和car及其应用
|
EP3807316B1
(en)
|
2018-06-18 |
2024-05-01 |
Innate Pharma |
Compositions and methods for treating cancer
|
CN110669135B
(zh)
|
2018-07-03 |
2022-11-11 |
上海健信生物医药科技有限公司 |
一种双特异性抗体及其用途
|
JP2021529814A
(ja)
|
2018-07-09 |
2021-11-04 |
グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッドGlaxosmithkline Intellectual Property Development Limited |
化学化合物
|
AR116109A1
(es)
|
2018-07-10 |
2021-03-31 |
Novartis Ag |
Derivados de 3-(5-amino-1-oxoisoindolin-2-il)piperidina-2,6-diona y usos de los mismos
|
KR20210030973A
(ko)
|
2018-07-11 |
2021-03-18 |
액팀 테라퓨틱스, 인코퍼레이티드 |
조작된 면역자극성 박테리아 균주 및 이의 용도
|
WO2020023268A1
(en)
|
2018-07-24 |
2020-01-30 |
Amgen Inc. |
Combination of lilrb1/2 pathway inhibitors and pd-1 pathway inhibitors
|
WO2020031107A1
(en)
|
2018-08-08 |
2020-02-13 |
Glaxosmithkline Intellectual Property Development Limited |
Chemical compounds
|
WO2020044206A1
(en)
|
2018-08-29 |
2020-03-05 |
Glaxosmithkline Intellectual Property Development Limited |
Heterocyclic amides as kinase inhibitors for use in the treatment cancer
|
AU2019340376A1
(en)
|
2018-09-11 |
2021-04-08 |
Curis Inc. |
Combination therapy with a phosphoinositide 3-kinase inhibitor with a zinc binding moiety
|
WO2020064971A1
(en)
|
2018-09-26 |
2020-04-02 |
Merck Patent Gmbh |
Combination of a pd-1 antagonist, an atr inhibitor and a platinating agent for the treatment of cancer
|
IL308722A
(en)
|
2018-10-17 |
2024-01-01 |
Biolinerx Ltd |
Treatment of metastatic adenocarcinoma of the pancreas
|
BR112021007517A2
(pt)
|
2018-10-22 |
2021-10-26 |
Glaxosmithkline Intellectual Property Development Limited |
Dosagem
|
BR112021008012A2
(pt)
|
2018-10-29 |
2021-11-03 |
Mersana Therapeutics Inc |
Conjugados de anticorpo de cisteína engenheirada-fármaco com ligantes contendo peptídeo
|
WO2020092183A1
(en)
|
2018-11-01 |
2020-05-07 |
Merck Sharp & Dohme Corp. |
Novel substituted pyrazole compounds as indoleamine 2,3-dioxygenase inhibitors
|
WO2020096871A1
(en)
|
2018-11-06 |
2020-05-14 |
Merck Sharp & Dohme Corp. |
Novel substituted tricyclic compounds as indoleamine 2,3-dioxygenase inhibitors
|
BR112021007448A2
(pt)
*
|
2018-11-14 |
2021-10-26 |
Bayer Aktiengesellschaft |
Combinação farmacêutica de anticorpos anti-ceacam6 e anti-pd-1 ou anti-pd-l1 para o tratamento de câncer
|
MX2021005651A
(es)
|
2018-11-16 |
2021-09-10 |
Arqule Inc |
Combinacion farmaceutica para el tratamiento contra el cancer.
|
WO2020106560A1
(en)
|
2018-11-20 |
2020-05-28 |
Merck Sharp & Dohme Corp. |
Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use
|
WO2020106558A1
(en)
|
2018-11-20 |
2020-05-28 |
Merck Sharp & Dohme Corp. |
Substituted amino triazolopyrimidine and amino triazolopyrazine adenosine receptor antagonists, pharmaceutical compositions and their use
|
EP3886842A1
(en)
|
2018-11-26 |
2021-10-06 |
Debiopharm International SA |
Combination treatment of hiv infections
|
WO2020112581A1
(en)
|
2018-11-28 |
2020-06-04 |
Merck Sharp & Dohme Corp. |
Novel substituted piperazine amide compounds as indoleamine 2, 3-dioxygenase (ido) inhibitors
|
WO2020110056A1
(en)
|
2018-11-30 |
2020-06-04 |
Glaxosmithkline Intellectual Property Development Limited |
Compounds useful in hiv therapy
|
MA54298A
(fr)
|
2018-11-30 |
2022-03-09 |
Merck Sharp & Dohme |
Dérivés amino triazolo quinazoline 9-substitués utiles en tant qu'antagonistes du récepteur de l'adénosine, compositions pharmaceutiques et leur utilisation
|
CA3117710A1
(en)
|
2018-12-11 |
2020-06-18 |
Theravance Biopharma R&D Ip, Llc |
Alk5 inhibitors
|
WO2020128972A1
(en)
|
2018-12-20 |
2020-06-25 |
Novartis Ag |
Dosing regimen and pharmaceutical combination comprising 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives
|
WO2020128893A1
(en)
|
2018-12-21 |
2020-06-25 |
Pfizer Inc. |
Combination treatments of cancer comprising a tlr agonist
|
CA3124935A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
3-(1-oxo-5-(piperidin-4-yl)isoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
WO2020165834A1
(en)
|
2019-02-15 |
2020-08-20 |
Novartis Ag |
Substituted 3-(1-oxoisoindolin-2-yl)piperidine-2,6-dione derivatives and uses thereof
|
CN109879855B
(zh)
*
|
2019-03-26 |
2021-01-05 |
中国医学科学院医药生物技术研究所 |
靶向肿瘤细胞表面pd-l1分子的抑制剂及其应用
|
US20220177465A1
(en)
|
2019-04-04 |
2022-06-09 |
Merck Sharp & Dohme Corp. |
Inhibitors of histone deacetylase-3 useful for the treatment of cancer, inflammation, neurodegeneration diseases and diabetes
|
JP2022529985A
(ja)
|
2019-04-19 |
2022-06-27 |
ヤンセン バイオテツク,インコーポレーテツド |
抗psma/cd3抗体で前立腺癌を治療する方法
|
KR20220002959A
(ko)
|
2019-04-23 |
2022-01-07 |
이나뜨 파르마 에스.에이. |
Cd73 차단 항체
|
WO2020232375A1
(en)
|
2019-05-16 |
2020-11-19 |
Silicon Swat, Inc. |
Oxoacridinyl acetic acid derivatives and methods of use
|
EP3969452A1
(en)
|
2019-05-16 |
2022-03-23 |
Stingthera, Inc. |
Benzo[b][1,8]naphthyridine acetic acid derivatives and methods of use
|
US20220241412A1
(en)
|
2019-05-24 |
2022-08-04 |
Pfizer Inc. |
Combination therapies using cdk inhibitors
|
EP3990635A1
(en)
|
2019-06-27 |
2022-05-04 |
Rigontec GmbH |
Design method for optimized rig-i ligands
|
GB201910305D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
GB201910304D0
(en)
|
2019-07-18 |
2019-09-04 |
Ctxt Pty Ltd |
Compounds
|
EP3999534A4
(en)
*
|
2019-07-19 |
2023-02-08 |
Beijing Sinotau Bio-Pharmaceuticals Technology Co., Ltd. |
NEW ANTI-PD-L1 ANTIBODIES AGAINST CD98 AND USE THEREOF
|
US11083705B2
(en)
|
2019-07-26 |
2021-08-10 |
Eisai R&D Management Co., Ltd. |
Pharmaceutical composition for treating tumor
|
JP2022543086A
(ja)
|
2019-08-02 |
2022-10-07 |
メルサナ セラピューティクス インコーポレイテッド |
がんの処置用のSTING(インターフェロン遺伝子刺激因子)アゴニストとしてのビス-[N-((5-カルバモイル)-1H-ベンゾ[d]イミダゾール-2-イル)-ピラゾール-5-カルボキサミド]誘導体および関連化合物
|
WO2021024020A1
(en)
|
2019-08-06 |
2021-02-11 |
Astellas Pharma Inc. |
Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer
|
WO2021053587A1
(en)
|
2019-09-18 |
2021-03-25 |
Klaus Strein |
Bispecific antibodies against ceacam5 and cd3
|
AU2020350137A1
(en)
|
2019-09-20 |
2022-04-28 |
Merck Patent Gmbh |
Combination of a poxvirus encoding HPV polypeptides and IL-2 with an anti-PD-L1 antibody
|
CA3155173A1
(en)
|
2019-09-27 |
2021-04-01 |
Glaxosmithkline Intellectual Property Development Limited |
Antigen binding proteins
|
AU2020373913B2
(en)
|
2019-10-28 |
2024-04-18 |
Shanghai Institute Of Materia Medica, Chinese Academy Of Sciences |
Five-membered heterocyclic oxocarboxylic acid compound and medical use thereof
|
TW202137984A
(zh)
|
2019-10-29 |
2021-10-16 |
日商衛材R&D企管股份有限公司 |
用於治療癌症之PD-1拮抗劑、VEGFR/FGFR/RET酪胺酸激酶抑制劑及CBP/β-連環蛋白抑制劑之組合
|
CN114728941A
(zh)
|
2019-11-22 |
2022-07-08 |
施万生物制药研发Ip有限责任公司 |
作为alk5抑制剂的经取代的1,5-萘啶或喹啉
|
EP3831849A1
(en)
|
2019-12-02 |
2021-06-09 |
LamKap Bio beta AG |
Bispecific antibodies against ceacam5 and cd47
|
US20230074558A1
(en)
|
2019-12-06 |
2023-03-09 |
Mersana Therapeutics, Inc. |
Dimeric compounds as sting agonists
|
US20230056470A1
(en)
|
2019-12-20 |
2023-02-23 |
Novartis Ag |
Uses of anti-tgf-beta antibodies and checkpoint inhibitors for the treatment of proliferative diseases
|
TW202204339A
(zh)
|
2020-03-31 |
2022-02-01 |
美商施萬生物製藥研發 Ip有限責任公司 |
經取代的嘧啶及使用方法
|
US20230149543A1
(en)
|
2020-04-14 |
2023-05-18 |
Glaxosmithkline Intellectual Property Development Limited |
Combination treatment for cancer based upon an icos antbody and a pd-l1 antibody tgf-bets-receptor fusion protein
|
TW202206100A
(zh)
|
2020-04-27 |
2022-02-16 |
美商西健公司 |
癌症之治療
|
EP4146644A1
(en)
|
2020-05-06 |
2023-03-15 |
Merck Sharp & Dohme LLC |
Il4i1 inhibitors and methods of use
|
WO2021249969A1
(en)
|
2020-06-10 |
2021-12-16 |
Merck Patent Gmbh |
Combination product for the treatment of cancer diseases
|
TW202214623A
(zh)
|
2020-06-10 |
2022-04-16 |
美商施萬生物製藥研發 Ip有限責任公司 |
結晶型alk5抑制劑及其用途
|
MX2022016069A
(es)
|
2020-06-19 |
2023-02-02 |
Hoffmann La Roche |
Anticuerpos que se unen a cd3 y cd19.
|
JP2023531676A
(ja)
|
2020-06-23 |
2023-07-25 |
ノバルティス アーゲー |
3-(1-オキソイソインドリン-2-イル)ピぺリジン-2,6-ジオン誘導体を含む投与レジメン
|
US20230293530A1
(en)
|
2020-06-24 |
2023-09-21 |
Yeda Research And Development Co. Ltd. |
Agents for sensitizing solid tumors to treatment
|
WO2022003554A1
(en)
|
2020-07-01 |
2022-01-06 |
Pfizer Inc. |
Biomarkers for pd-1 axis binding antagonist therapy
|
CA3182579A1
(en)
|
2020-07-07 |
2022-01-13 |
Ugur Sahin |
Therapeutic rna for hpv-positive cancer
|
MX2023002570A
(es)
|
2020-09-02 |
2023-05-19 |
Pharmabcine Inc |
Terapia de combinacion de un antagonista de pd-1 y un antagonista para vegfr-2 para tratar a pacientes con cancer.
|
EP4055055B1
(en)
|
2020-12-18 |
2023-11-22 |
LamKap Bio beta AG |
Bispecific antibodies against ceacam5 and cd47
|
TW202245808A
(zh)
|
2020-12-21 |
2022-12-01 |
德商拜恩迪克公司 |
用於治療癌症之治療性rna
|
WO2022135667A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Therapeutic rna for treating cancer
|
WO2022135666A1
(en)
|
2020-12-21 |
2022-06-30 |
BioNTech SE |
Treatment schedule for cytokine proteins
|
US20240059789A1
(en)
|
2021-01-28 |
2024-02-22 |
Janssen Biotech, Inc. |
Psma binding proteins and uses thereof
|
CA3206906A1
(en)
|
2021-02-02 |
2022-08-11 |
Andras Herner |
Selective bcl-xl protac compounds and methods of use
|
IL305427A
(en)
|
2021-03-02 |
2023-10-01 |
Glaxosmithkline Ip Dev Ltd |
Substituted pyridines as DNMT1 inhibitors
|
WO2022195551A1
(en)
|
2021-03-18 |
2022-09-22 |
Novartis Ag |
Biomarkers for cancer and methods of use thereof
|
TW202304506A
(zh)
|
2021-03-25 |
2023-02-01 |
日商安斯泰來製藥公司 |
涉及抗claudin 18.2抗體的組合治療以治療癌症
|
EP4314060A1
(en)
|
2021-03-31 |
2024-02-07 |
GlaxoSmithKline Intellectual Property Development Limited |
Antigen binding proteins and combinations thereof
|
TW202304979A
(zh)
|
2021-04-07 |
2023-02-01 |
瑞士商諾華公司 |
抗TGFβ抗體及其他治療劑用於治療增殖性疾病之用途
|
AU2022254104A1
(en)
|
2021-04-08 |
2023-10-26 |
Nurix Therapeutics, Inc. |
Combination therapies with cbl-b inhibitor compounds
|
EP4320156A1
(en)
|
2021-04-09 |
2024-02-14 |
Ose Immunotherapeutics |
Scaffold for bifunctioanl molecules comprising pd-1 or cd28 and sirp binding domains
|
IL307419A
(en)
|
2021-04-09 |
2023-12-01 |
Ose Immunotherapeutics |
A new scaffold for bifunctional molecules with improved properties
|
WO2022227015A1
(en)
|
2021-04-30 |
2022-11-03 |
Merck Sharp & Dohme Corp. |
Il4i1 inhibitors and methods of use
|
AR125874A1
(es)
|
2021-05-18 |
2023-08-23 |
Novartis Ag |
Terapias de combinación
|
WO2022251359A1
(en)
|
2021-05-26 |
2022-12-01 |
Theravance Biopharma R&D Ip, Llc |
Bicyclic inhibitors of alk5 and methods of use
|
EP4351595A1
(en)
|
2021-06-07 |
2024-04-17 |
Providence Health & Services - Oregon |
Cxcr5, pd-1, and icos expressing tumor reactive cd4 t cells and their use
|
AU2022312698A1
(en)
|
2021-07-13 |
2024-01-25 |
BioNTech SE |
Multispecific binding agents against cd40 and cd137 in combination therapy for cancer
|
CA3227386A1
(en)
*
|
2021-07-28 |
2023-02-02 |
Jianing Huang |
Interleukin-2 muteins, fusion proteins, pharmaceutical compositions, and therapeutic applications
|
WO2023010080A1
(en)
|
2021-07-30 |
2023-02-02 |
Seagen Inc. |
Treatment for cancer
|
WO2023039583A1
(en)
*
|
2021-09-10 |
2023-03-16 |
Trustees Of Tufts College |
Anti-pd-1 immunoglobulin polypeptides and uses thereof
|
WO2023051926A1
(en)
|
2021-09-30 |
2023-04-06 |
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