DK3328419T3 - Pd-1-bindingsmolekyler og fremgangsmåder til anvendelse deraf - Google Patents

Pd-1-bindingsmolekyler og fremgangsmåder til anvendelse deraf Download PDF

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Publication number
DK3328419T3
DK3328419T3 DK16831339.3T DK16831339T DK3328419T3 DK 3328419 T3 DK3328419 T3 DK 3328419T3 DK 16831339 T DK16831339 T DK 16831339T DK 3328419 T3 DK3328419 T3 DK 3328419T3
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methods
binding molecules
molecules
binding
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DK16831339.3T
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Danish (da)
English (en)
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Kalpana Shah
Douglas H Smith
Motte-Mohs Ross La
Leslie S Johnson
Paul A Moore
Ezio Bonvini
Scott Koenig
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Macrogenics Inc
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • G—PHYSICS
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    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
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    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577—Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6872—Intracellular protein regulatory factors and their receptors, e.g. including ion channels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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    • C07—ORGANIC CHEMISTRY
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
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DK16831339.3T 2015-07-30 2016-07-28 Pd-1-bindingsmolekyler og fremgangsmåder til anvendelse deraf DK3328419T3 (da)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201562198867P 2015-07-30 2015-07-30
US201562239559P 2015-10-09 2015-10-09
US201562255140P 2015-11-13 2015-11-13
US201662322974P 2016-04-15 2016-04-15
PCT/US2016/044430 WO2017019846A1 (en) 2015-07-30 2016-07-28 Pd-1-binding molecules and methods use thereof

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DK3328419T3 true DK3328419T3 (da) 2021-10-11

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DK16831339.3T DK3328419T3 (da) 2015-07-30 2016-07-28 Pd-1-bindingsmolekyler og fremgangsmåder til anvendelse deraf
DK18199685.1T DK3456346T3 (da) 2015-07-30 2016-07-28 Pd-1- og lag-3-bindingsmolekyler og fremgangsmåder til anvendelse deraf
DK21191711.7T DK3981792T3 (da) 2015-07-30 2016-07-28 PD-1-bindende molekyler og fremgangsmåder til anvendelse deraf

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DK18199685.1T DK3456346T3 (da) 2015-07-30 2016-07-28 Pd-1- og lag-3-bindingsmolekyler og fremgangsmåder til anvendelse deraf
DK21191711.7T DK3981792T3 (da) 2015-07-30 2016-07-28 PD-1-bindende molekyler og fremgangsmåder til anvendelse deraf

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US (3) US10577422B2 (OSRAM)
EP (4) EP4450088A3 (OSRAM)
JP (5) JP6959907B2 (OSRAM)
KR (3) KR20250020718A (OSRAM)
CN (4) CN107847574B (OSRAM)
AU (5) AU2016298227B9 (OSRAM)
CA (1) CA2993948A1 (OSRAM)
CL (1) CL2018000254A1 (OSRAM)
CO (1) CO2018000867A2 (OSRAM)
CR (3) CR20220194A (OSRAM)
CY (3) CY1124634T1 (OSRAM)
DK (3) DK3328419T3 (OSRAM)
EA (1) EA201890296A1 (OSRAM)
EC (1) ECSP18006831A (OSRAM)
ES (3) ES2898958T3 (OSRAM)
FI (2) FI3981792T3 (OSRAM)
FR (1) FR24C1033I2 (OSRAM)
GE (3) GEP20227419B (OSRAM)
HR (3) HRP20241289T1 (OSRAM)
HU (4) HUE068868T2 (OSRAM)
IL (4) IL297090B2 (OSRAM)
JO (2) JO3736B1 (OSRAM)
LT (4) LT3981792T (OSRAM)
MA (2) MA58293B1 (OSRAM)
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NL (1) NL301287I2 (OSRAM)
PE (3) PE20231958A1 (OSRAM)
PH (1) PH12018500232A1 (OSRAM)
PL (3) PL3328419T3 (OSRAM)
PT (3) PT3328419T (OSRAM)
RS (3) RS62374B1 (OSRAM)
SG (2) SG10202010506TA (OSRAM)
SI (3) SI3328419T1 (OSRAM)
SM (3) SMT202100610T1 (OSRAM)
TW (5) TWI886756B (OSRAM)
UA (1) UA127372C2 (OSRAM)
WO (1) WO2017019846A1 (OSRAM)
ZA (2) ZA201800500B (OSRAM)

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RU2718692C2 (ru) * 2014-05-29 2020-04-13 Мэкроудженикс, Инк. Триспецифичные связывающие молекулы, которые специфически связывают антигены множества злокачественных опухолей, и способы их применения
TWI693232B (zh) * 2014-06-26 2020-05-11 美商宏觀基因股份有限公司 與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
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