DK1758565T4 - Fremgangsmåde til identifikation af GLP-1-sekretionsfremkaldende stoffer. - Google Patents

Fremgangsmåde til identifikation af GLP-1-sekretionsfremkaldende stoffer.

Info

Publication number
DK1758565T4
DK1758565T4 DK06717678.4T DK06717678T DK1758565T4 DK 1758565 T4 DK1758565 T4 DK 1758565T4 DK 06717678 T DK06717678 T DK 06717678T DK 1758565 T4 DK1758565 T4 DK 1758565T4
Authority
DK
Denmark
Prior art keywords
identifying glp
inducers
secretion
secretion inducers
glp
Prior art date
Application number
DK06717678.4T
Other languages
Danish (da)
English (en)
Other versions
DK1758565T3 (da
Inventor
James N Leonard
Hussien A Al-Shamma
Robert M Jones
Zhi-Liang Chu
Original Assignee
Arena Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36570727&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK1758565(T4) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Arena Pharm Inc filed Critical Arena Pharm Inc
Application granted granted Critical
Publication of DK1758565T3 publication Critical patent/DK1758565T3/da
Publication of DK1758565T4 publication Critical patent/DK1758565T4/da

Links

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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A—HUMAN NECESSITIES
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
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    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
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    • G01N2800/28—Neurological disorders
    • G01N2800/2871—Cerebrovascular disorders, e.g. stroke, cerebral infarct, cerebral haemorrhage, transient ischemic event

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Food Science & Technology (AREA)
  • Cardiology (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biotechnology (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Reproductive Health (AREA)
  • Psychology (AREA)
DK06717678.4T 2005-01-10 2006-01-09 Fremgangsmåde til identifikation af GLP-1-sekretionsfremkaldende stoffer. DK1758565T4 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US64308605P 2005-01-10 2005-01-10
US68317205P 2005-05-19 2005-05-19
US72688005P 2005-10-14 2005-10-14
PCT/US2006/000510 WO2006076231A2 (en) 2005-01-10 2006-01-09 Combination therapy for the treatment of diabetes and conditions related thereto and for the treatment of conditions ameliorated by increasing a blood glp-1 level

Publications (2)

Publication Number Publication Date
DK1758565T3 DK1758565T3 (da) 2009-09-07
DK1758565T4 true DK1758565T4 (da) 2013-02-04

Family

ID=36570727

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06717678.4T DK1758565T4 (da) 2005-01-10 2006-01-09 Fremgangsmåde til identifikation af GLP-1-sekretionsfremkaldende stoffer.
DK07004743T DK1808168T3 (da) 2005-01-10 2006-01-09 Kombinationsterapi til behandling af diabetes og tilstande relateret hertil og til behandling af tilstande, der lindres ved at öge et blod-GLP-1-niveau

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK07004743T DK1808168T3 (da) 2005-01-10 2006-01-09 Kombinationsterapi til behandling af diabetes og tilstande relateret hertil og til behandling af tilstande, der lindres ved at öge et blod-GLP-1-niveau

Country Status (35)

Country Link
US (12) US20060154866A1 (enExample)
EP (9) EP2322151A3 (enExample)
JP (8) JP4118323B1 (enExample)
KR (5) KR101016890B1 (enExample)
CN (2) CN102218141A (enExample)
AR (1) AR052082A1 (enExample)
AT (2) ATE431139T1 (enExample)
AU (3) AU2006205164B2 (enExample)
BR (1) BRPI0606727A (enExample)
CA (2) CA2593427C (enExample)
CL (1) CL2010000565A1 (enExample)
CR (1) CR9220A (enExample)
CY (2) CY1109260T1 (enExample)
DE (2) DE602006006765D1 (enExample)
DK (2) DK1758565T4 (enExample)
DO (2) DOP2006000008A (enExample)
EA (1) EA011883B1 (enExample)
ES (2) ES2327872T3 (enExample)
GT (1) GT200600004A (enExample)
HN (1) HN2006000971A (enExample)
HR (2) HRP20090403T4 (enExample)
IL (1) IL184364A0 (enExample)
MX (1) MX2007008376A (enExample)
NI (1) NI200700174A (enExample)
NO (2) NO331089B1 (enExample)
NZ (4) NZ556219A (enExample)
PA (1) PA8659301A1 (enExample)
PE (2) PE20100398A1 (enExample)
PL (2) PL1758565T5 (enExample)
PT (2) PT1758565E (enExample)
RS (2) RS51127B (enExample)
SG (2) SG158876A1 (enExample)
SI (2) SI1758565T1 (enExample)
TW (1) TW200637534A (enExample)
WO (1) WO2006076231A2 (enExample)

Families Citing this family (98)

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CZ305402B6 (cs) * 2001-02-24 2015-09-02 Boehringer Ingelheim Pharma Gmbh & Co. Kg Xanthinové deriváty, jejich výroba a použití v kombinační terapii
EP2022505B1 (en) 2001-07-31 2011-12-14 The Government of the United States of America, as represented by the Secretary of the Department of Health and Human Services GLP-1, exendin-4, peptide analogs and uses thereof
US7407955B2 (en) 2002-08-21 2008-08-05 Boehringer Ingelheim Pharma Gmbh & Co., Kg 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions
PT1599468E (pt) 2003-01-14 2008-01-14 Arena Pharm Inc Derivados de arilo e heteroarilo 1,2,3.-trissubstituídos comomoduladores do metabolismo, e profilaxia e tratamento dedesordens relacionadas tais como diabetes e hiperglicemia
AR045047A1 (es) * 2003-07-11 2005-10-12 Arena Pharm Inc Derivados arilo y heteroarilo trisustituidos como moduladores del metabolismo y de la profilaxis y tratamiento de desordenes relacionados con los mismos
EP2287165A3 (en) 2003-07-14 2011-06-22 Arena Pharmaceuticals, Inc. Fused-aryl and heteroaryl derivatives as modulators of metabolism and the prophylaxis and treatment of disorders related thereto
US7501426B2 (en) 2004-02-18 2009-03-10 Boehringer Ingelheim International Gmbh 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions
DE102004054054A1 (de) 2004-11-05 2006-05-11 Boehringer Ingelheim Pharma Gmbh & Co. Kg Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine
NZ556017A (en) * 2004-12-24 2009-10-30 Prosidion Ltd G-protein coupled receptor (gpr116) agonists and use thereof for treating obesity and diabetes
MY148521A (en) * 2005-01-10 2013-04-30 Arena Pharm Inc Substituted pyridinyl and pyrimidinyl derivatives as modulators of metabolism and the treatment of disorders related thereto
DOP2006000008A (es) * 2005-01-10 2006-08-31 Arena Pharm Inc Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1
CN101166527A (zh) 2005-04-27 2008-04-23 艾尼纳制药公司 用于治疗肥胖症和糖尿病以及其相关病况和用于治疗可通过增加血液glp-1含量改善的病况的组合疗法
MX2007016508A (es) * 2005-06-30 2008-03-04 Prosidion Ltd Agonistas del receptor acoplado a la proteina g.
DE102005035891A1 (de) 2005-07-30 2007-02-08 Boehringer Ingelheim Pharma Gmbh & Co. Kg 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel
US20070179123A1 (en) * 2005-11-08 2007-08-02 Chiang Peter K Methods and compositions for treating diseases associated with pathogenic proteins
DK1971862T3 (da) * 2006-04-11 2011-02-14 Arena Pharm Inc Fremgangsmåder til anvendelse af GPR119-receptor til identificering af forbindelser anvendelige til øgning af knoglemasse hos en person
PE20071221A1 (es) * 2006-04-11 2007-12-14 Arena Pharm Inc Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas
EA030606B1 (ru) 2006-05-04 2018-08-31 Бёрингер Ингельхайм Интернациональ Гмбх Способы приготовления лекарственного средства, содержащего полиморфы
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