DE59500788D1
(de)
*
|
1994-05-03 |
1997-11-20 |
Ciba Geigy Ag |
Pyrrolopyrimidinderivate mit antiproliferativer Wirkung
|
TW321649B
(de)
*
|
1994-11-12 |
1997-12-01 |
Zeneca Ltd |
|
GB9424233D0
(en)
*
|
1994-11-30 |
1995-01-18 |
Zeneca Ltd |
Quinazoline derivatives
|
GB9508565D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quiazoline derivative
|
GB9508535D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivative
|
GB9508537D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
GB9508538D0
(en)
*
|
1995-04-27 |
1995-06-14 |
Zeneca Ltd |
Quinazoline derivatives
|
EP0824525B1
(de)
*
|
1995-04-27 |
2001-06-13 |
AstraZeneca AB |
Chinazolin derivate
|
US6395733B1
(en)
*
|
1995-06-07 |
2002-05-28 |
Pfizer Inc |
Heterocyclic ring-fused pyrimidine derivatives
|
US6228871B1
(en)
|
1995-07-10 |
2001-05-08 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
GB9624482D0
(en)
*
|
1995-12-18 |
1997-01-15 |
Zeneca Phaema S A |
Chemical compounds
|
ES2177925T3
(es)
*
|
1996-01-23 |
2002-12-16 |
Novartis Ag |
Pirrolopirimidinas y procedimientos para su preparacion.
|
US6184225B1
(en)
|
1996-02-13 |
2001-02-06 |
Zeneca Limited |
Quinazoline derivatives as VEGF inhibitors
|
GB9603097D0
(en)
*
|
1996-02-14 |
1996-04-10 |
Zeneca Ltd |
Quinazoline compounds
|
DE69709319T2
(de)
|
1996-03-05 |
2002-08-14 |
Astrazeneca Ab |
4-anilinochinazolin derivate
|
GB9607729D0
(en)
*
|
1996-04-13 |
1996-06-19 |
Zeneca Ltd |
Quinazoline derivatives
|
GB9707800D0
(en)
|
1996-05-06 |
1997-06-04 |
Zeneca Ltd |
Chemical compounds
|
ES2297864T3
(es)
|
1996-08-23 |
2008-05-01 |
Novartis Ag |
Pirrolopirimidinas sustituidas y procesos para su preparacion.
|
AU733551B2
(en)
|
1996-09-25 |
2001-05-17 |
Astrazeneca Ab |
Qinoline derivatives inhibiting the effect of growth factors such as VEGF
|
GB9718972D0
(en)
|
1996-09-25 |
1997-11-12 |
Zeneca Ltd |
Chemical compounds
|
ATE291022T1
(de)
|
1996-10-02 |
2005-04-15 |
Novartis Pharma Gmbh |
Pyrimiderivate und verfahren zu ihrer herstellung
|
HUP9903330A2
(hu)
|
1996-11-19 |
2000-03-28 |
Amgen Inc. |
Gyulladásgátló hatású, aril- és heteroaril csoporttal szubsztituált kondenzált pirrolszármazékok, valamint ezeket tartalmazó gyógyászati készítmények
|
EP0946554A1
(de)
*
|
1996-11-27 |
1999-10-06 |
Pfizer Inc. |
Kondensierte bicyclische pyramidinderivate
|
US7863444B2
(en)
|
1997-03-19 |
2011-01-04 |
Abbott Laboratories |
4-aminopyrrolopyrimidines as kinase inhibitors
|
WO1998043973A1
(de)
*
|
1997-03-27 |
1998-10-08 |
Novartis Ag |
Zwischenprodukte und verfahren zur herstellung von pyrimidinderivaten
|
US6235741B1
(en)
|
1997-05-30 |
2001-05-22 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
EP0889127A1
(de)
*
|
1997-07-01 |
1999-01-07 |
Smithkline Beecham Corporation |
Serine/Threonine Protein Kinase (H-SGK2)
|
AU8816298A
(en)
|
1997-08-22 |
1999-03-16 |
Zeneca Limited |
Oxindolylquinazoline derivatives as angiogenesis inhibitors
|
US6465484B1
(en)
|
1997-09-26 |
2002-10-15 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
US6162804A
(en)
*
|
1997-09-26 |
2000-12-19 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
US6380203B1
(en)
|
1998-01-14 |
2002-04-30 |
Merck & Co., Inc. |
Angiogenesis inhibitors
|
US6423716B1
(en)
|
1998-03-31 |
2002-07-23 |
Kyowa Hakko Kogyo Co., Ltd. |
Nitrogenous heterocyclic compounds
|
US6878716B1
(en)
|
1998-06-02 |
2005-04-12 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A1 receptor and uses thereof
|
US6686366B1
(en)
|
1998-06-02 |
2004-02-03 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A3 receptor and uses thereof
|
ID27600A
(id)
|
1998-06-02 |
2001-04-12 |
Osi Pharm Inc |
KOMPOSISI PIROLO (2,3d) PIRIMIDIN DAN PENGGUNAANNYA
|
RS50087B
(sr)
|
1998-06-19 |
2009-01-22 |
Pfizer Products Inc., |
Pirolo (2,3-d) pirimidin jedinjenja
|
PA8474101A1
(es)
|
1998-06-19 |
2000-09-29 |
Pfizer Prod Inc |
Compuestos de pirrolo [2,3-d] pirimidina
|
US6017918A
(en)
*
|
1998-08-06 |
2000-01-25 |
Warner-Lambert Company |
Phenyl glycine compounds and methods of treating atherosclerosis and restenosis
|
US6284795B1
(en)
|
1998-09-04 |
2001-09-04 |
Warner-Lambert Company |
Sulfonamide compounds and methods of treating atherosclerosis and restenosis
|
US6713474B2
(en)
|
1998-09-18 |
2004-03-30 |
Abbott Gmbh & Co. Kg |
Pyrrolopyrimidines as therapeutic agents
|
CN1326457A
(zh)
*
|
1998-09-18 |
2001-12-12 |
巴斯福股份公司 |
作为激酶抑制剂的4-氨基吡咯并嘧啶
|
UA71945C2
(en)
*
|
1999-01-27 |
2005-01-17 |
Pfizer Prod Inc |
Substituted bicyclic derivatives being used as anticancer agents
|
MXPA01012899A
(es)
|
1999-06-21 |
2002-07-30 |
Boehringer Ingelheim Pharma |
Heterociclos biciclicos, medicamentos que contienen estos compuestos, su empleo y procedimientos para su preparacion.
|
GB9925958D0
(en)
|
1999-11-02 |
1999-12-29 |
Bundred Nigel J |
Therapeutic use
|
KR100849151B1
(ko)
|
1999-11-05 |
2008-07-30 |
아스트라제네카 아베 |
Vegf 억제제로서의 퀴나졸린 유도체
|
US6664252B2
(en)
|
1999-12-02 |
2003-12-16 |
Osi Pharmaceuticals, Inc. |
4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof
|
US7160890B2
(en)
|
1999-12-02 |
2007-01-09 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A3 receptor and uses thereof
|
US6680322B2
(en)
|
1999-12-02 |
2004-01-20 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A1 receptors and uses thereof
|
PT1382339E
(pt)
|
1999-12-10 |
2008-02-06 |
Pfizer Prod Inc |
Composições que contêm derivados de pirrolo[2,3-d]- pirimidina
|
OA12292A
(en)
|
2000-06-26 |
2003-11-11 |
Pfizer Prod Inc |
PyrroloÄ2,3-dÜpyrimidine compounds as immunosuppressive agents.
|
EP1170011A1
(de)
*
|
2000-07-06 |
2002-01-09 |
Boehringer Ingelheim International GmbH |
Neue Verwendung von Inhibitoren der Rezeptoren des epidermalen Wachstumsfaktors
|
US7776315B2
(en)
|
2000-10-31 |
2010-08-17 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Pharmaceutical compositions based on anticholinergics and additional active ingredients
|
ES2290199T3
(es)
*
|
2000-11-22 |
2008-02-16 |
Novartis Ag |
Mezcla que incluye un agente que reduce la actividad de fcve y un agente que reduce la actividad de fce.
|
US6680324B2
(en)
|
2000-12-01 |
2004-01-20 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A1 receptors and uses thereof
|
US6673802B2
(en)
|
2000-12-01 |
2004-01-06 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A3 receptor and uses thereof
|
US7019012B2
(en)
|
2000-12-20 |
2006-03-28 |
Boehringer Ingelheim International Pharma Gmbh & Co. Kg |
Quinazoline derivatives and pharmaceutical compositions containing them
|
CA2994779C
(en)
|
2001-02-19 |
2020-08-25 |
Novartis Ag |
Use of 40-o-(2-hydroxyethyl)-rapamycin for inhibiting growth of a solid tumour of the brain other than lymphatic cancer
|
CN1511036B
(zh)
*
|
2001-02-27 |
2010-05-05 |
诺瓦提斯公司 |
包含信号转导抑制剂和埃坡霉素衍生物的联合形式
|
BR0209647A
(pt)
|
2001-05-16 |
2004-07-27 |
Novartis Ag |
Combinação que compreende n-{5-[4-(4-metil-piperazino-metil)-benzoilamido]-2-metil fenil}-4-(3-piridil)-2-pirimidina-amina e um agente quimioterapêutico
|
US7301023B2
(en)
|
2001-05-31 |
2007-11-27 |
Pfizer Inc. |
Chiral salt resolution
|
US7323469B2
(en)
|
2001-08-07 |
2008-01-29 |
Novartis Ag |
7H-pyrrolo[2,3-d]pyrimidine derivatives
|
GB0119249D0
(en)
*
|
2001-08-07 |
2001-10-03 |
Novartis Ag |
Organic compounds
|
EP1435959A2
(de)
*
|
2001-10-09 |
2004-07-14 |
University of Cincinnati |
Egf rezeptor hemmer zur behandlung von schilddrüsentumoren
|
JP2005507424A
(ja)
*
|
2001-10-29 |
2005-03-17 |
ノバルティス アクチエンゲゼルシャフト |
固形腫瘍の処置における7H−ピロロ[2,3−d]ピリミジン誘導体の使用
|
US7504407B2
(en)
|
2001-11-30 |
2009-03-17 |
Osi Pharmaceuticals, Inc. |
Compounds specific to adenosine A1 and A3 receptors and uses thereof
|
CN1816551A
(zh)
|
2001-12-20 |
2006-08-09 |
Osi药物公司 |
吡咯并嘧啶A2b选择性拮抗剂化合物,它们的合成及用途
|
EA007468B1
(ru)
|
2001-12-20 |
2006-10-27 |
Оси Фармасьютикалз, Инк. |
Пиримидиновые соединения, относящиеся к a-селективным антагонистам, их синтез и применение
|
AU2002360774A1
(en)
*
|
2001-12-28 |
2003-07-24 |
Bayer Corporation |
4-substituted fused heteropyrimidines and fused hetero-4-pyrimidones
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
DE10221018A1
(de)
|
2002-05-11 |
2003-11-27 |
Boehringer Ingelheim Pharma |
Verwendung von Hemmern der EGFR-vermittelten Signaltransduktion zur Behandlung von gutartiger Prostatahyperplasie (BPH)/Prostatahypertrophie
|
PL372103A1
(en)
|
2002-05-16 |
2005-07-11 |
Novartis Ag |
Use of edg receptor binding agents in cancer
|
US20040048887A1
(en)
*
|
2002-07-09 |
2004-03-11 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Pharmaceutical compositions based on anticholinergics and EGFR kinase inhibitors
|
KR20050086784A
(ko)
|
2002-11-26 |
2005-08-30 |
화이자 프로덕츠 인크. |
이식 거부반응의 치료 방법
|
US7223749B2
(en)
|
2003-02-20 |
2007-05-29 |
Boehringer Ingelheim International Gmbh |
Bicyclic heterocycles, pharmaceutical compositions containing these compounds, their use and processes for preparing them
|
MY150088A
(en)
|
2003-05-19 |
2013-11-29 |
Irm Llc |
Immunosuppressant compounds and compositions
|
CL2004001120A1
(es)
|
2003-05-19 |
2005-04-15 |
Irm Llc |
Compuestos derivados de amina sustituidas con heterociclos, inmunosupresores; composicion farmaceutica; y uso para tratar enfermedades mediadas por interacciones de linfocito, tales como enfermedades autoinmunes, inflamatorias, infecciosas, cancer.
|
KR101126560B1
(ko)
|
2003-05-30 |
2012-04-05 |
도꾜 다이가꾸 |
약제 반응 예측 방법
|
AU2004268621C1
(en)
|
2003-08-29 |
2011-08-18 |
Exelixis, Inc. |
c-Kit modulators and methods of use
|
DE10349113A1
(de)
|
2003-10-17 |
2005-05-12 |
Boehringer Ingelheim Pharma |
Verfahren zur Herstellung von Aminocrotonylverbindungen
|
WO2005039588A2
(en)
*
|
2003-10-22 |
2005-05-06 |
Novartis Ag |
Methods for determining the risk of developing liver and lung toxicity
|
US20050239806A1
(en)
*
|
2004-01-13 |
2005-10-27 |
Ambit Biosciences Corporation |
Pyrrolopyrimidine derivatives and analogs and their use in the treatment and prevention of diseases
|
AU2005231956B2
(en)
|
2004-04-07 |
2009-11-05 |
Novartis Ag |
Inhibitors of IAP
|
US8080577B2
(en)
|
2004-05-06 |
2011-12-20 |
Bioresponse, L.L.C. |
Diindolylmethane formulations for the treatment of leiomyomas
|
RU2389731C2
(ru)
*
|
2004-06-02 |
2010-05-20 |
Такеда Фармасьютикал Компани Лимитед |
Конденсированное гетероциклическое соединение
|
GB0512324D0
(en)
|
2005-06-16 |
2005-07-27 |
Novartis Ag |
Organic compounds
|
EP1768982A2
(de)
|
2004-06-29 |
2007-04-04 |
Amgen Inc. |
Pyrolo[2,3-d] pyrimidine, die die ack1- und lck-aktivität modulieren
|
AR050365A1
(es)
*
|
2004-08-02 |
2006-10-18 |
Osi Pharm Inc |
Compuestos inhibidores de multi- quinasa pirrolopirimidina aril- amino sustituidos.
|
US20060035893A1
(en)
|
2004-08-07 |
2006-02-16 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for treatment of respiratory and gastrointestinal disorders
|
PE20060777A1
(es)
|
2004-12-24 |
2006-10-06 |
Boehringer Ingelheim Int |
Derivados de indolinona para el tratamiento o la prevencion de enfermedades fibroticas
|
EP1838303B1
(de)
|
2004-12-30 |
2011-02-09 |
Bioresponse LLC |
Verwendung von diindolylmethan-verwandten indolen zur behandlung und prävention von erkrankungen im zusammenhang mit dem respiratory syncytial virus
|
US20090155247A1
(en)
*
|
2005-02-18 |
2009-06-18 |
Ashkenazi Avi J |
Methods of Using Death Receptor Agonists and EGFR Inhibitors
|
CR9465A
(es)
*
|
2005-03-25 |
2008-06-19 |
Surface Logix Inc |
Compuestos mejorados farmacocineticamente
|
GB0510390D0
(en)
|
2005-05-20 |
2005-06-29 |
Novartis Ag |
Organic compounds
|
US20080227980A1
(en)
*
|
2005-08-05 |
2008-09-18 |
Novartis Ag |
Preparation of a 7H-Pyrrolo [2,3-D] Pyrimidine Derivative
|
US8119655B2
(en)
*
|
2005-10-07 |
2012-02-21 |
Takeda Pharmaceutical Company Limited |
Kinase inhibitors
|
WO2007054550A1
(en)
|
2005-11-11 |
2007-05-18 |
Boehringer Ingelheim International Gmbh |
Quinazoline derivatives for the treatment of cancer diseases
|
PT2275103E
(pt)
|
2005-11-21 |
2014-07-24 |
Novartis Ag |
Inibidores de mtor para o tratamento de tumores endócrinos
|
ES2700433T3
(es)
|
2005-12-13 |
2019-02-15 |
Incyte Holdings Corp |
Derivados de pirrolo[2,3-d]pirimidina como inhibidores de quinasas Janus
|
GB0605120D0
(en)
|
2006-03-14 |
2006-04-26 |
Novartis Ag |
Organic Compounds
|
EP2606890A1
(de)
|
2006-04-05 |
2013-06-26 |
Novartis AG |
Kombinationen aus BCR-ABL/C-KIT/PDGF-R TK-Hemmern zu Krebsbehandlung
|
US20090098137A1
(en)
|
2006-04-05 |
2009-04-16 |
Novartis Ag |
Combinations of therapeutic agents for treating cancer
|
CN101443002B
(zh)
|
2006-05-09 |
2012-03-21 |
诺瓦提斯公司 |
包含铁螯合剂和抗肿瘤药的组合及其用途
|
WO2008033747A2
(en)
*
|
2006-09-11 |
2008-03-20 |
Curis, Inc. |
Multi-functional small molecules as anti-proliferative agents
|
US20080161320A1
(en)
*
|
2006-09-11 |
2008-07-03 |
Xiong Cai |
Fused bicyclic pyrimidines as ptk inhibitors containing a zinc binding moiety
|
ATE522625T1
(de)
|
2006-09-12 |
2011-09-15 |
Genentech Inc |
Verfahren und zusammensetzungen zur diagnose und behandlung von lungenkrebs mittels pdgfra-, kit- oder kdg-gen als genmarker
|
EP2068880B1
(de)
|
2006-09-18 |
2012-04-11 |
Boehringer Ingelheim International GmbH |
Verfahren zur behandlung von tumoren mit egfr-mutationen
|
CA2664378A1
(en)
|
2006-09-29 |
2008-04-03 |
Novartis Ag |
Pyrazolopyrimidines as pi3k lipid kinase inhibitors
|
US8586621B2
(en)
|
2006-10-27 |
2013-11-19 |
Michael A. Zeligs |
Anti-parasitic methods and compositions utilizing diindolylmethane-related indoles
|
EP2120900A2
(de)
|
2007-02-15 |
2009-11-25 |
Novartis AG |
Kombinationen von lb589 mit anderen therapeutischen wirkstoffen zur krebsbehandlung
|
CL2008001709A1
(es)
|
2007-06-13 |
2008-11-03 |
Incyte Corp |
Compuestos derivados de pirrolo [2,3-b]pirimidina, moduladores de quinasas jak; composicion farmaceutica; y uso en el tratamiento de enfermedades tales como cancer, psoriasis, artritis reumatoide, entre otras.
|
HUE029236T2
(en)
|
2007-06-13 |
2017-02-28 |
Incyte Holdings Corp |
(R) -3- (4- (7H-Pyrrolo [2,3-d] pyrimidin-4-yl) -1H-pyrazol-1-yl) -3-cyclopentylpropanenitrile Crystalline salts of Janus kinase inhibitor
|
DE102007027800A1
(de)
|
2007-06-16 |
2008-12-18 |
Bayer Healthcare Ag |
Substituierte bicyclische Heteroaryl-Verbindungen und ihre Verwendung
|
WO2009004329A1
(en)
|
2007-07-02 |
2009-01-08 |
Cancer Research Technology Limited |
9h-pyrimido[4,5-b]indoles, 9h-pyrido[4',3':4,5]pyrrolo[2,3-d]pyridines, and 9h-1,3,6,9-tetraaza-fluorenes as chk1 kinase function inhibitors
|
WO2009067543A2
(en)
*
|
2007-11-19 |
2009-05-28 |
The Regents Of The University Of Colorado |
Treatment of histone deacetylase mediated disorders
|
NZ586642A
(en)
|
2008-01-11 |
2012-04-27 |
Natco Pharma Ltd |
Novel pyrazolo [3, 4 -d] pyrimidine derivatives as anti -cancer agents
|
TWI472339B
(zh)
|
2008-01-30 |
2015-02-11 |
Genentech Inc |
包含結合至her2結構域ii之抗體及其酸性變異體的組合物
|
DK2288610T3
(en)
|
2008-03-11 |
2016-11-28 |
Incyte Holdings Corp |
Azetidinesulfonic AND CYCLOBUTANDERIVATER AS JAK INHIBITORS
|
DE102008021699A1
(de)
*
|
2008-04-25 |
2009-10-29 |
Schebo Biotech Ag |
Neue Pyrrolopyrimidin-Derivate und deren Verwendung
|
KR101673621B1
(ko)
|
2008-03-24 |
2016-11-07 |
노파르티스 아게 |
아릴술폰아미드-계 매트릭스 메탈로프로테아제 억제제
|
EP2628726A1
(de)
|
2008-03-26 |
2013-08-21 |
Novartis AG |
Auf Hydroxamat basierende Hemmer von Deacetylasen B
|
ME01269B
(me)
|
2008-08-20 |
2013-06-20 |
Zoetis Services Llc |
Jedinjenja pirolo (2,3-d) pirimidina
|
ES2704986T3
(es)
|
2008-10-16 |
2019-03-21 |
Celator Pharmaceuticals Inc |
Combinaciones de una camptotecina liposomal soluble en agua con cetuximab o bevacizumab
|
US8710104B2
(en)
|
2008-11-07 |
2014-04-29 |
Triact Therapeutics, Inc. |
Catecholic butanes and use thereof for cancer therapy
|
KR101703941B1
(ko)
*
|
2008-11-10 |
2017-02-07 |
내셔날 헬스 리서치 인스티튜트 |
티로신 키나아제 억제제로서의 접합 이환 및 삼환 피리미딘 화합물
|
RU2011129230A
(ru)
|
2008-12-18 |
2013-01-27 |
Новартис Аг |
Новая полиморфная форма 1-[4-[1-(4-циклогексил-3-трифторметилбензилоксиимино)этил]-2-этилбензил]азетидин-3-карбоновой кислоты
|
CN103204794A
(zh)
|
2008-12-18 |
2013-07-17 |
诺瓦提斯公司 |
新的盐
|
UY32330A
(es)
|
2008-12-18 |
2010-07-30 |
Novartis Ag |
Novedosa forma de sal de ácido 1-(4-{1-[e-4-ciclohexil-3-trifluoro-metil-benciloxi-imino]-etil}-2-etil-bencil)-azetidin-3-carboxílico, formas polimórficas, composiciones farmacéuticas conteniéndolas, procesos de preparación y aplicaciones
|
WO2010083617A1
(en)
|
2009-01-21 |
2010-07-29 |
Oncalis Ag |
Pyrazolopyrimidines as protein kinase inhibitors
|
TW201031406A
(en)
|
2009-01-29 |
2010-09-01 |
Novartis Ag |
Substituted benzimidazoles for the treatment of astrocytomas
|
US20120189641A1
(en)
|
2009-02-25 |
2012-07-26 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
US20110171124A1
(en)
|
2009-02-26 |
2011-07-14 |
Osi Pharmaceuticals, Inc. |
In situ methods for monitoring the EMT status of tumor cells in vivo
|
US8642834B2
(en)
|
2009-02-27 |
2014-02-04 |
OSI Pharmaceuticals, LLC |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
EP2401613A2
(de)
|
2009-02-27 |
2012-01-04 |
OSI Pharmaceuticals, LLC |
Verfahren zur identifizierung von mesenchymähnlichen tumorzellen oder deren bildung hemmenden stoffen
|
WO2010099138A2
(en)
|
2009-02-27 |
2010-09-02 |
Osi Pharmaceuticals, Inc. |
Methods for the identification of agents that inhibit mesenchymal-like tumor cells or their formation
|
JP2012520893A
(ja)
|
2009-03-18 |
2012-09-10 |
オーエスアイ・ファーマシューティカルズ,エルエルシー |
Egfr阻害薬及びigf−1r阻害剤の投与を含む組み合わせ癌治療
|
TW201544123A
(zh)
|
2009-03-20 |
2015-12-01 |
Genentech Inc |
抗-her抗體
|
WO2010135650A1
(en)
|
2009-05-22 |
2010-11-25 |
Incyte Corporation |
N-(HETERO)ARYL-PYRROLIDINE DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AND PYRROL-3-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS
|
WO2010135621A1
(en)
|
2009-05-22 |
2010-11-25 |
Incyte Corporation |
3-[4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl]octane- or heptane-nitrile as jak inhibitors
|
UA105794C2
(uk)
|
2009-06-26 |
2014-06-25 |
Новартіс Аг |
1,3-ДИЗАМІЩЕНІ ПОХІДНІ ІМІДАЗОЛІДИН-2-ОНУ ЯК ІНГІБІТОРИ Cyp17
|
EP2451445B1
(de)
|
2009-07-06 |
2019-04-03 |
Boehringer Ingelheim International GmbH |
Verfahren zur trocknung von bibw2992, seiner salze und fester pharmazeutischer formulierungen mit diesem wirkstoff
|
CA2768821A1
(en)
*
|
2009-07-28 |
2011-02-03 |
Ube Industries, Ltd. |
Pyrrolo[2,3-d]pyrimidine derivative
|
US8389526B2
(en)
|
2009-08-07 |
2013-03-05 |
Novartis Ag |
3-heteroarylmethyl-imidazo[1,2-b]pyridazin-6-yl derivatives
|
AU2010283806A1
(en)
|
2009-08-12 |
2012-03-01 |
Novartis Ag |
Heterocyclic hydrazone compounds and their uses to treat cancer and inflammation
|
MX2012002066A
(es)
|
2009-08-17 |
2012-03-29 |
Intellikine Inc |
Compuestos heterociclicos y usos de los mismos.
|
JP5775871B2
(ja)
|
2009-08-20 |
2015-09-09 |
ノバルティス アーゲー |
ヘテロ環式オキシム化合物
|
EP2470502A1
(de)
|
2009-08-26 |
2012-07-04 |
Novartis AG |
Tetra-substituierte heteroarylverbindungen und ihre verwendung als mdm2- und/oder mdm4-modulatoren
|
TW201113285A
(en)
|
2009-09-01 |
2011-04-16 |
Incyte Corp |
Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
|
IN2012DN02139A
(de)
|
2009-09-10 |
2015-08-07 |
Novartis Ag |
|
EP2486041B1
(de)
|
2009-10-09 |
2013-08-14 |
Incyte Corporation |
Hydroxyl-, keto-,und glucuronidderivate aus 3-(4-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)-1h-pyrazol-1-yl)-3-cyclopentylpropannitril
|
AU2010317167B2
(en)
|
2009-11-04 |
2012-11-29 |
Novartis Ag |
Heterocyclic sulfonamide derivatives useful as MEK inhibitors
|
RU2012124093A
(ru)
|
2009-11-12 |
2013-12-20 |
Дженентек, Инк. |
Способ увеличения плотности дендритных шипиков
|
WO2011058164A1
(en)
|
2009-11-13 |
2011-05-19 |
Pangaea Biotech, S.A. |
Molecular biomarkers for predicting response to tyrosine kinase inhibitors in lung cancer
|
JP6220126B2
(ja)
|
2009-11-23 |
2017-10-25 |
セルリアン・ファーマ・インコーポレイテッド |
治療的送達のためのシクロデキストリンに基づく重合体
|
US20120289501A1
(en)
|
2009-11-25 |
2012-11-15 |
Novartis Ag |
Benzene-fused 6-membered oxygen-containing heterocyclic derivatives of bicyclic heteroaryls
|
EP2509964B1
(de)
|
2009-12-08 |
2014-04-30 |
Novartis AG |
Heterocyclische Sulfonamidderivate
|
US8440693B2
(en)
|
2009-12-22 |
2013-05-14 |
Novartis Ag |
Substituted isoquinolinones and quinazolinones
|
CU24130B1
(es)
|
2009-12-22 |
2015-09-29 |
Novartis Ag |
Isoquinolinonas y quinazolinonas sustituidas
|
CA2781578A1
(en)
|
2010-01-12 |
2011-07-21 |
F. Hoffmann-La Roche Ag |
Tricyclic heterocyclic compounds, compositions and methods of use thereof
|
US20110178287A1
(en)
|
2010-01-19 |
2011-07-21 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for therapeutic delivery
|
US9556249B2
(en)
|
2010-02-18 |
2017-01-31 |
Genentech, Inc. |
Neuregulin antagonists and use thereof in treating cancer
|
ES2662588T3
(es)
|
2010-03-10 |
2018-04-09 |
Incyte Holdings Corporation |
Derivados de piperidin-4-IL azetidina como inhibidores de JAK1
|
MX2012010265A
(es)
|
2010-03-17 |
2012-10-01 |
Hoffmann La Roche |
Compuestos de imidazopiridina, composiciones y metodos de uso.
|
US20110237686A1
(en)
|
2010-03-26 |
2011-09-29 |
Cerulean Pharma Inc |
Formulations and methods of use
|
JP2013528787A
(ja)
|
2010-04-16 |
2013-07-11 |
ジェネンテック, インコーポレイテッド |
Pi3k/aktキナーゼ経路インヒビターの効果の予測バイオマーカーとしてのfox03a
|
EP2582680A1
(de)
|
2010-06-17 |
2013-04-24 |
Novartis AG |
Biphenyl-substituierte 1,3-dihydro-benzoimidazol-2-ylidenamidderivate
|
JP2013532149A
(ja)
|
2010-06-17 |
2013-08-15 |
ノバルティス アーゲー |
ピペリジニル置換1,3−ジヒドロ−ベンゾイミダゾール−2−イリデンアミン誘導体
|
UA112517C2
(uk)
|
2010-07-06 |
2016-09-26 |
Новартіс Аг |
Тетрагідропіридопіримідинові похідні
|
DK2612151T3
(en)
|
2010-08-31 |
2017-10-02 |
Genentech Inc |
BIOMARKETS AND METHODS OF TREATMENT
|
RU2013114352A
(ru)
|
2010-09-15 |
2014-10-20 |
Ф. Хоффманн-Ля Рош Аг |
Азабензотиазолы, композиции и способы применения
|
US8946260B2
(en)
|
2010-09-16 |
2015-02-03 |
Novartis Ag |
17α-hydroxylase/C17,20-lyase inhibitors
|
AU2011329734B2
(en)
|
2010-11-19 |
2015-05-28 |
Incyte Holdings Corporation |
Cyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors
|
WO2012068440A1
(en)
|
2010-11-19 |
2012-05-24 |
Incyte Corporation |
Heterocyclic-substituted pyrrolopyridines and pyrrolopyrimidines as jak inhibitors
|
MX2013005445A
(es)
|
2010-11-19 |
2013-07-29 |
Hoffmann La Roche |
Pirazolopiridinas y el uso de pirazolopiridinas como inhibidores de tirosina cinasa 2 (tyk2).
|
BR112013015449A2
(pt)
|
2010-12-21 |
2016-09-20 |
Novartis Ag |
compostos de bi-heteroarila como inibidores de vps23
|
EP2468883A1
(de)
|
2010-12-22 |
2012-06-27 |
Pangaea Biotech S.L. |
Molekulare Biomarker zur Vorhersage der Reaktion auf Tyrosinkinaseinhibitoren bei Lungenkrebs
|
WO2012085176A1
(en)
|
2010-12-23 |
2012-06-28 |
F. Hoffmann-La Roche Ag |
Tricyclic pyrazinone compounds, compositions and methods of use thereof as janus kinase inhibitors
|
US9134297B2
(en)
|
2011-01-11 |
2015-09-15 |
Icahn School Of Medicine At Mount Sinai |
Method and compositions for treating cancer and related methods
|
US20130324526A1
(en)
|
2011-02-10 |
2013-12-05 |
Novartis Ag |
[1,2,4] triazolo [4,3-b] pyridazine compounds as inhibitors of the c-met tyrosine kinase
|
EP2492688A1
(de)
|
2011-02-23 |
2012-08-29 |
Pangaea Biotech, S.A. |
Molekulare Biomarker zur Vorhersage der Reaktion auf die Antitumorbehandlung bei Lungenkrebs
|
JP5808826B2
(ja)
|
2011-02-23 |
2015-11-10 |
インテリカイン, エルエルシー |
複素環化合物およびその使用
|
KR102061743B1
(ko)
|
2011-03-04 |
2020-01-03 |
뉴젠 세러퓨틱스 인코포레이티드 |
알킨 치환된 퀴나졸린 화합물 및 그것의 사용 방법
|
WO2012120469A1
(en)
|
2011-03-08 |
2012-09-13 |
Novartis Ag |
Fluorophenyl bicyclic heteroaryl compounds
|
TWI527818B
(zh)
*
|
2011-03-15 |
2016-04-01 |
特留斯治療學有限公司 |
三環旋轉酶抑制劑
|
WO2012129145A1
(en)
|
2011-03-18 |
2012-09-27 |
OSI Pharmaceuticals, LLC |
Nscle combination therapy
|
WO2012149014A1
(en)
|
2011-04-25 |
2012-11-01 |
OSI Pharmaceuticals, LLC |
Use of emt gene signatures in cancer drug discovery, diagnostics, and treatment
|
KR20140025492A
(ko)
|
2011-04-28 |
2014-03-04 |
노파르티스 아게 |
17α-히드록실라제/C17,20-리아제 억제제
|
EA201391820A1
(ru)
|
2011-06-09 |
2014-12-30 |
Новартис Аг |
Гетероциклические сульфонамидные производные
|
MY165963A
(en)
|
2011-06-20 |
2018-05-18 |
Incyte Holdings Corp |
Azetidinyl phenyl, pyridyl or pyrazinyl carboxamide derivatives as jak inhibitors
|
US8859586B2
(en)
|
2011-06-20 |
2014-10-14 |
Novartis Ag |
Cyclohexyl isoquinolinone compounds
|
US8859535B2
(en)
|
2011-06-20 |
2014-10-14 |
Novartis Ag |
Hydroxy substituted isoquinolinone derivatives
|
EA201490164A1
(ru)
|
2011-06-27 |
2014-04-30 |
Новартис Аг |
Твердые формы и соли производных тетрагидропиридопиримидина
|
WO2013007765A1
(en)
|
2011-07-13 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Fused tricyclic compounds for use as inhibitors of janus kinases
|
WO2013007768A1
(en)
|
2011-07-13 |
2013-01-17 |
F. Hoffmann-La Roche Ag |
Tricyclic heterocyclic compounds, compositions and methods of use thereof as jak inhibitors
|
CA2843499A1
(en)
|
2011-08-12 |
2013-02-21 |
F. Hoffmann-La Roche Ag |
Indazole compounds, compositions and methods of use
|
CN103890007A
(zh)
|
2011-08-17 |
2014-06-25 |
霍夫曼-拉罗奇有限公司 |
神经调节蛋白抗体及其用途
|
TW201313721A
(zh)
|
2011-08-18 |
2013-04-01 |
Incyte Corp |
作為jak抑制劑之環己基氮雜環丁烷衍生物
|
EP2751285B2
(de)
|
2011-08-31 |
2020-04-01 |
Genentech, Inc. |
Methode zur bestimmung der empfindlichkeit eines tumors für egfr kinase-inhibitoren
|
UA111854C2
(uk)
|
2011-09-07 |
2016-06-24 |
Інсайт Холдінгс Корпорейшн |
Способи і проміжні сполуки для отримання інгібіторів jak
|
WO2013038362A1
(en)
|
2011-09-15 |
2013-03-21 |
Novartis Ag |
6 - substituted 3 - (quinolin- 6 - ylthio) - [1,2,4] triazolo [4, 3 -a] pyradines as tyrosine kinase
|
BR112014006643A2
(pt)
|
2011-09-20 |
2017-04-04 |
Hoffmann La Roche |
compostos de imidazopiridina, composições e métodos de uso dos mesmos
|
KR20140066783A
(ko)
|
2011-09-30 |
2014-06-02 |
제넨테크, 인크. |
종양 또는 종양 세포에서의 상피 또는 중간엽 표현형 및 egfr 키나제 억제제에 대한 반응의 진단 메틸화 마커
|
BR112014010938A2
(pt)
|
2011-11-09 |
2017-05-16 |
Cancer Res Tech Ltd |
compostos de 5-(piridin-2-il-amino)-pirazina-2-carbonitrila e seu uso terapêutico
|
US8969341B2
(en)
|
2011-11-29 |
2015-03-03 |
Novartis Ag |
Pyrazolopyrrolidine compounds
|
WO2013081645A2
(en)
|
2011-11-30 |
2013-06-06 |
Genentech, Inc. |
Erbb3 mutations in cancer
|
US9408885B2
(en)
|
2011-12-01 |
2016-08-09 |
Vib Vzw |
Combinations of therapeutic agents for treating melanoma
|
WO2013093850A1
(en)
|
2011-12-22 |
2013-06-27 |
Novartis Ag |
Quinoline derivatives
|
SI2794600T1
(en)
|
2011-12-22 |
2018-03-30 |
Novartis Ag |
2,3-Dihydro-benzo (1,4) oxazine derivatives and related compounds as phosphoinositide-3 kinase inhibitors (PI3K) for the treatment, e.g. rheumatoid arthritis
|
CA2859869A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
BR112014015308A2
(pt)
|
2011-12-23 |
2017-06-13 |
Novartis Ag |
compostos para inibição da interação de bcl2 com contrapartes de ligação
|
US20130178520A1
(en)
|
2011-12-23 |
2013-07-11 |
Duke University |
Methods of treatment using arylcyclopropylamine compounds
|
WO2013096051A1
(en)
|
2011-12-23 |
2013-06-27 |
Novartis Ag |
Compounds for inhibiting the interaction of bcl2 with binding partners
|
BR112014015274A8
(pt)
|
2011-12-23 |
2017-06-13 |
Novartis Ag |
compostos e composições para inibição da interação de bcl2 com parceiros de ligação
|
AU2012355624A1
(en)
|
2011-12-23 |
2014-07-17 |
Novartis Ag |
Compounds for inhibiting the interaction of BCL2 with binding partners
|
UY34591A
(es)
|
2012-01-26 |
2013-09-02 |
Novartis Ag |
Compuestos de imidazopirrolidinona
|
SG11201404241SA
(en)
|
2012-01-27 |
2014-08-28 |
Univ Montreal |
Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells
|
RU2014136886A
(ru)
|
2012-03-27 |
2016-05-20 |
Дженентек, Инк. |
Диагностика и виды лечения, связанные с ингибиторами her3
|
CN104245701A
(zh)
|
2012-04-03 |
2014-12-24 |
诺华有限公司 |
有酪氨酸激酶抑制剂的组合产品和其应用
|
WO2013152252A1
(en)
|
2012-04-06 |
2013-10-10 |
OSI Pharmaceuticals, LLC |
Combination anti-cancer therapy
|
EP2855448B1
(de)
|
2012-05-15 |
2017-02-08 |
Cancer Research Technology Ltd |
5-[[4-[[morpholin-2-yl]methylamino]-5-(trifluormethyl)-2-pyridyl]amino]pyrazin-2-carbonitril und therapeutische verwendungen davon
|
US9193733B2
(en)
|
2012-05-18 |
2015-11-24 |
Incyte Holdings Corporation |
Piperidinylcyclobutyl substituted pyrrolopyridine and pyrrolopyrimidine derivatives as JAK inhibitors
|
US9365576B2
(en)
|
2012-05-24 |
2016-06-14 |
Novartis Ag |
Pyrrolopyrrolidinone compounds
|
WO2013188763A1
(en)
|
2012-06-15 |
2013-12-19 |
The Brigham And Women's Hospital, Inc. |
Compositions for treating cancer and methods for making the same
|
WO2013190089A1
(en)
|
2012-06-21 |
2013-12-27 |
Pangaea Biotech, S.L. |
Molecular biomarkers for predicting outcome in lung cancer
|
US9738643B2
(en)
|
2012-08-06 |
2017-08-22 |
Duke University |
Substituted indazoles for targeting Hsp90
|
WO2014064131A2
(en)
*
|
2012-10-26 |
2014-05-01 |
F. Hoffmann-La Roche Ag |
Inhibitors of bruton's tyrosine kinase
|
WO2014071402A1
(en)
|
2012-11-05 |
2014-05-08 |
Dana-Farber Cancer Institute, Inc. |
Xbp1, cd138, and cs1, pharmaceutical compositions that include the peptides, and methods of using such petides and compositions
|
CN102936251A
(zh)
*
|
2012-11-05 |
2013-02-20 |
上海毕得医药科技有限公司 |
一种吡咯并[2,3-d]嘧啶衍生物的制备方法
|
EA201590930A1
(ru)
|
2012-11-15 |
2015-08-31 |
Инсайт Корпорейшн |
Лекарственные формы руксолитиниба с замедленным высвобождением
|
TW201422625A
(zh)
|
2012-11-26 |
2014-06-16 |
Novartis Ag |
二氫-吡啶并-□衍生物之固體形式
|
EP2948451B1
(de)
|
2013-01-22 |
2017-07-12 |
Novartis AG |
Substituierte purinonverbindungen
|
WO2014115080A1
(en)
|
2013-01-22 |
2014-07-31 |
Novartis Ag |
Pyrazolo[3,4-d]pyrimidinone compounds as inhibitors of the p53/mdm2 interaction
|
EP3626741A1
(de)
|
2013-02-20 |
2020-03-25 |
The Trustees Of The University Of Pennsylvania |
Behandlung von krebs mit humanisiertem chimärem anti-egfrviii-antigenrezeptor
|
WO2014128612A1
(en)
|
2013-02-20 |
2014-08-28 |
Novartis Ag |
Quinazolin-4-one derivatives
|
CN104994879A
(zh)
|
2013-02-22 |
2015-10-21 |
霍夫曼-拉罗奇有限公司 |
治疗癌症和预防药物抗性的方法
|
AU2014223548A1
(en)
|
2013-02-26 |
2015-10-15 |
Triact Therapeutics, Inc. |
Cancer therapy
|
JP2016510751A
(ja)
|
2013-03-06 |
2016-04-11 |
ジェネンテック, インコーポレイテッド |
抗がん剤耐性を治療及び予防する方法
|
CN105189509B
(zh)
|
2013-03-06 |
2017-12-19 |
因赛特公司 |
用于制备jak抑制剂的方法及中间体
|
US10035801B2
(en)
|
2013-03-13 |
2018-07-31 |
Genentech, Inc. |
Pyrazolo compounds and uses thereof
|
BR112015022604A2
(pt)
|
2013-03-14 |
2017-10-24 |
Genentech Inc |
usos de um modulador de modificador de cromatina e um antagonista de egfr
|
CA2903480A1
(en)
|
2013-03-14 |
2014-09-25 |
Genentech, Inc. |
Combinations of a mek inhibitor compound with an her3/egfr inhibitor compound and methods of use
|
CN105246482A
(zh)
|
2013-03-15 |
2016-01-13 |
因特利凯有限责任公司 |
激酶抑制剂的组合及其用途
|
EP2968537A1
(de)
|
2013-03-15 |
2016-01-20 |
Genentech, Inc. |
Verfahren zur behandlung von krebs und prävention einer antikrebsmittelresistenz
|
EP2976085A1
(de)
|
2013-03-21 |
2016-01-27 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Verfahren und pharmazeutische zusammensetzung zur verwendung bei der behandlung von chronischen lebererkrankungen im zusammenhang mit einer niedrigen hepcidinexpression
|
WO2014155268A2
(en)
|
2013-03-25 |
2014-10-02 |
Novartis Ag |
Fgf-r tyrosine kinase activity inhibitors - use in diseases associated with lack of or reduced snf5 activity
|
KR20160061911A
(ko)
|
2013-04-08 |
2016-06-01 |
데니스 엠. 브라운 |
최적하 투여된 화학 화합물의 치료 효과
|
US20150018376A1
(en)
|
2013-05-17 |
2015-01-15 |
Novartis Ag |
Pyrimidin-4-yl)oxy)-1h-indole-1-carboxamide derivatives and use thereof
|
UY35675A
(es)
|
2013-07-24 |
2015-02-27 |
Novartis Ag |
Derivados sustituidos de quinazolin-4-ona
|
SI3030227T1
(sl)
|
2013-08-07 |
2020-08-31 |
Incyte Corporation |
Dozirne oblike s podaljšanim sproščanjem za inhibitor JAK1
|
WO2015022663A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
US9227969B2
(en)
|
2013-08-14 |
2016-01-05 |
Novartis Ag |
Compounds and compositions as inhibitors of MEK
|
WO2015022664A1
(en)
|
2013-08-14 |
2015-02-19 |
Novartis Ag |
Compounds and compositions as inhibitors of mek
|
RU2016112568A
(ru)
|
2013-09-05 |
2017-10-06 |
Дженентек, Инк. |
Антипролиферативные соединения
|
CA2923667A1
(en)
|
2013-09-09 |
2015-03-12 |
Triact Therapeutics, Inc. |
Cancer therapy
|
RU2675105C9
(ru)
|
2013-09-22 |
2019-01-09 |
Саншайн Лейк Фарма Ко., Лтд. |
Замещенные аминопиримидиновые соединения и способы их использования
|
TW201605857A
(zh)
|
2013-10-03 |
2016-02-16 |
赫孚孟拉羅股份公司 |
Cdk8之醫療性抑制劑及其用途
|
KR20160070136A
(ko)
|
2013-10-18 |
2016-06-17 |
제넨테크, 인크. |
항-rspo2 및/또는 항-rspo3 항체 및 그의 용도
|
WO2015084804A1
(en)
|
2013-12-03 |
2015-06-11 |
Novartis Ag |
Combination of mdm2 inhibitor and braf inhibitor and their use
|
NZ720515A
(en)
|
2013-12-17 |
2022-12-23 |
Genentech Inc |
Methods of treating cancers using pd-1 axis binding antagonists and taxanes
|
CA2934028A1
(en)
|
2013-12-17 |
2015-06-25 |
Genentech, Inc. |
Combination therapy comprising ox40 binding agonists and pd-1 axis binding antagonists
|
US9242965B2
(en)
|
2013-12-31 |
2016-01-26 |
Boehringer Ingelheim International Gmbh |
Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors
|
MA39776A
(fr)
|
2014-03-24 |
2017-02-01 |
Hoffmann La Roche |
Traitement du cancer avec des antagonistes de c-met et corrélation de ces derniers avec l'expression de hgf
|
WO2015148714A1
(en)
|
2014-03-25 |
2015-10-01 |
Duke University |
Heat shock protein 70 (hsp-70) receptor ligands
|
WO2015145388A2
(en)
|
2014-03-27 |
2015-10-01 |
Novartis Ag |
Methods of treating colorectal cancers harboring upstream wnt pathway mutations
|
US9394281B2
(en)
|
2014-03-28 |
2016-07-19 |
Calitor Sciences, Llc |
Substituted heteroaryl compounds and methods of use
|
RU2016142476A
(ru)
|
2014-03-31 |
2018-05-07 |
Дженентек, Инк. |
Комбинированная терапия, включающая антиангиогенезные агенты и агонисты, связывающие ох40
|
MA51552A
(fr)
|
2014-03-31 |
2021-03-24 |
Hoffmann La Roche |
Anticorps anti-ox40 et procédés d'utilisation
|
AU2015241198A1
(en)
|
2014-04-03 |
2016-11-17 |
Invictus Oncology Pvt. Ltd. |
Supramolecular combinatorial therapeutics
|
US20170027940A1
(en)
|
2014-04-10 |
2017-02-02 |
Stichting Het Nederlands Kanker Instituut |
Method for treating cancer
|
WO2015184305A1
(en)
|
2014-05-30 |
2015-12-03 |
Incyte Corporation |
TREATMENT OF CHRONIC NEUTROPHILIC LEUKEMIA (CNL) AND ATYPICAL CHRONIC MYELOID LEUKEMIA (aCML) BY INHIBITORS OF JAK1
|
WO2016011658A1
(en)
|
2014-07-25 |
2016-01-28 |
Novartis Ag |
Combination therapy
|
US10414733B2
(en)
|
2014-07-31 |
2019-09-17 |
Basf Se |
Process for preparing pyrazoles
|
JP6526789B2
(ja)
|
2014-07-31 |
2019-06-05 |
ノバルティス アーゲー |
組み合わせ療法
|
WO2016036873A1
(en)
|
2014-09-05 |
2016-03-10 |
Genentech, Inc. |
Therapeutic compounds and uses thereof
|
EP3193866A1
(de)
|
2014-09-19 |
2017-07-26 |
Genentech, Inc. |
Verwendung von cbp/ep300- und bet-inhibitoren zur behandlung von krebs
|
CN107912040B
(zh)
|
2014-10-10 |
2021-04-06 |
基因泰克公司 |
作为组蛋白脱甲基酶抑制剂的吡咯烷酰胺化合物
|
CN107109484B
(zh)
|
2014-11-03 |
2021-12-14 |
豪夫迈·罗氏有限公司 |
用于ox40激动剂治疗的功效预测和评估的方法和生物标志物
|
CN106796235B
(zh)
|
2014-11-03 |
2021-01-29 |
豪夫迈·罗氏有限公司 |
用于检测t细胞免疫子集的测定法及其使用方法
|
CN107073126A
(zh)
|
2014-11-06 |
2017-08-18 |
豪夫迈·罗氏有限公司 |
包含ox40结合激动剂和tigit抑制剂的组合疗法
|
EP3218376B1
(de)
|
2014-11-10 |
2019-12-25 |
Genentech, Inc. |
Bromodomaininhibitoren und deren verwendung
|
MA40940A
(fr)
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
|
MA40943A
(fr)
|
2014-11-10 |
2017-09-19 |
Constellation Pharmaceuticals Inc |
Pyrrolopyridines substituées utilisées en tant qu'inhibiteurs de bromodomaines
|
BR112017010198A2
(pt)
|
2014-11-17 |
2017-12-26 |
Genentech Inc |
terapia de combinação compreendendo agonistas de ligação a ox40 e antagonistas de ligação ao eixo de pd-1
|
WO2016086200A1
(en)
|
2014-11-27 |
2016-06-02 |
Genentech, Inc. |
4,5,6,7-tetrahydro-1 h-pyrazolo[4,3-c]pyridin-3-amine compounds as cbp and/or ep300 inhibitors
|
JP2018508183A
(ja)
|
2014-12-23 |
2018-03-29 |
ジェネンテック, インコーポレイテッド |
化学療法耐性癌を治療及び診断する組成物及び方法
|
CN107223163A
(zh)
|
2014-12-24 |
2017-09-29 |
豪夫迈·罗氏有限公司 |
用于膀胱癌症的治疗,诊断和预后方法
|
JP2018503373A
(ja)
|
2014-12-30 |
2018-02-08 |
ジェネンテック, インコーポレイテッド |
がんの予後診断及び治療のための方法及び組成物
|
CN107406418B
(zh)
|
2015-01-09 |
2021-10-29 |
基因泰克公司 |
4,5-二氢咪唑衍生物及其作为组蛋白脱甲基酶(kdm2b)抑制剂的用途
|
JP6659703B2
(ja)
|
2015-01-09 |
2020-03-04 |
ジェネンテック, インコーポレイテッド |
ピリダジノン誘導体および癌の処置におけるそれらの使用
|
JP6855379B2
(ja)
|
2015-01-09 |
2021-04-07 |
ジェネンテック, インコーポレイテッド |
癌の処置のためのヒストンデメチラーゼkdm2bのインヒビターとしての(ピペリジン−3−イル)(ナフタレン−2−イル)メタノン誘導体および関連化合物
|
WO2016123391A1
(en)
|
2015-01-29 |
2016-08-04 |
Genentech, Inc. |
Therapeutic compounds and uses thereof
|
CN107438593B
(zh)
|
2015-01-30 |
2020-10-30 |
基因泰克公司 |
治疗化合物及其用途
|
MA41598A
(fr)
|
2015-02-25 |
2018-01-02 |
Constellation Pharmaceuticals Inc |
Composés thérapeutiques de pyridazine et leurs utilisations
|
MX2017012805A
(es)
|
2015-04-07 |
2018-04-11 |
Genentech Inc |
Complejo de unión a antígenos con actividad agonista y métodos de uso.
|
US10584102B2
(en)
*
|
2015-05-11 |
2020-03-10 |
Basf Se |
Process for preparing 4-amino-pyridazines
|
JP7048319B2
(ja)
|
2015-05-12 |
2022-04-05 |
ジェネンテック, インコーポレイテッド |
癌のための治療方法及び診断方法
|
JP7144935B2
(ja)
|
2015-05-29 |
2022-09-30 |
ジェネンテック, インコーポレイテッド |
癌のための治療方法及び診断方法
|
KR102278306B1
(ko)
|
2015-06-05 |
2021-07-15 |
헤마-퀘벡 |
조혈 줄기세포를 전구 세포로 배양 및/또는 분화시키는 방법 및 그의 용도
|
MX2017014740A
(es)
|
2015-06-08 |
2018-08-15 |
Genentech Inc |
Métodos de tratamiento del cáncer con anticuerpos anti-ox40.
|
MX2017015937A
(es)
|
2015-06-08 |
2018-12-11 |
Genentech Inc |
Métodos de tratamiento del cáncer con anticuerpos anti-ox40 y antagonistas de unión al eje de pd-1.
|
EP3310815A1
(de)
|
2015-06-17 |
2018-04-25 |
F. Hoffmann-La Roche AG |
Verfahren zur behandlung von lokal fortgeschrittenen oder metastatischen brustkrebsen unter verwendung von pd-1-achse-bindenden antagonisten und taxanen
|
FR3037959B1
(fr)
|
2015-06-23 |
2017-08-04 |
Servier Lab |
Nouveaux derives bicycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
EP3341376B1
(de)
|
2015-08-26 |
2020-12-23 |
Fundación del Sector Público Estatal Centro Nacional de Investigaciones Oncológicas Carlos III (F.S.P. CNIO) |
Kondensierte tricyclische verbindungen als hemmer von protein kinase
|
WO2017044434A1
(en)
|
2015-09-11 |
2017-03-16 |
Sunshine Lake Pharma Co., Ltd. |
Substituted heteroaryl compounds and methods of use
|
AU2016369528B2
(en)
|
2015-12-16 |
2021-04-22 |
Genentech, Inc. |
Process for the preparation of tricyclic PI3K inhibitor compounds and methods for using the same for the treatment of cancer
|
ES2837428T3
(es)
|
2016-01-08 |
2021-06-30 |
Hoffmann La Roche |
Procedimientos de tratamiento de cánceres positivos para CEA usando antagonistas de unión al eje PD-1 y anticuerpos biespecíficos anti-CEA/anti-CD3
|
JP6821693B2
(ja)
|
2016-02-29 |
2021-01-27 |
ジェネンテック, インコーポレイテッド |
がんのための治療方法及び診断方法
|
US20170319688A1
(en)
|
2016-04-14 |
2017-11-09 |
Genentech, Inc. |
Anti-rspo3 antibodies and methods of use
|
KR20190003958A
(ko)
|
2016-04-15 |
2019-01-10 |
제넨테크, 인크. |
암의 치료 및 모니터링 방법
|
KR20180134347A
(ko)
|
2016-04-15 |
2018-12-18 |
제넨테크, 인크. |
암의 진단 및 치료 방법
|
WO2017181079A2
(en)
|
2016-04-15 |
2017-10-19 |
Genentech, Inc. |
Methods for monitoring and treating cancer
|
US11261187B2
(en)
|
2016-04-22 |
2022-03-01 |
Duke University |
Compounds and methods for targeting HSP90
|
JP7160688B2
(ja)
|
2016-05-24 |
2022-10-25 |
ジェネンテック, インコーポレイテッド |
Cbp/ep300の複素環式インヒビターおよびがんの処置におけるそれらの使用
|
CN109476663B
(zh)
|
2016-05-24 |
2021-11-09 |
基因泰克公司 |
用于治疗癌症的吡唑并吡啶衍生物
|
US20200129519A1
(en)
|
2016-06-08 |
2020-04-30 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
EP3494139B1
(de)
|
2016-08-05 |
2022-01-12 |
F. Hoffmann-La Roche AG |
Multivalente und multiepitopische anitikörper mit agonistischer wirkung und verfahren zur verwendung
|
CN109476748B
(zh)
|
2016-08-08 |
2023-05-23 |
豪夫迈·罗氏有限公司 |
用于癌症的治疗和诊断方法
|
WO2018039203A1
(en)
|
2016-08-23 |
2018-03-01 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating multiple myeloma
|
US20190209669A1
(en)
|
2016-08-23 |
2019-07-11 |
Oncopep, Inc. |
Peptide vaccines and durvalumab for treating breast cancer
|
CA3035080A1
(en)
|
2016-09-27 |
2018-04-05 |
Cero Therapeutics, Inc. |
Chimeric engulfment receptor molecules
|
US10207998B2
(en)
|
2016-09-29 |
2019-02-19 |
Duke University |
Substituted benzimidazole and substituted benzothiazole inhibitors of transforming growth factor-β kinase and methods of use thereof
|
US10927083B2
(en)
|
2016-09-29 |
2021-02-23 |
Duke University |
Substituted benzimidazoles as inhibitors of transforming growth factor-β kinase
|
EP3523451A1
(de)
|
2016-10-06 |
2019-08-14 |
Genentech, Inc. |
Therapeutische und diagnostische verfahren für krebs
|
JP2019535250A
(ja)
|
2016-10-29 |
2019-12-12 |
ジェネンテック, インコーポレイテッド |
抗mic抗体及び使用方法
|
BR112019012976A2
(pt)
|
2016-12-22 |
2019-12-31 |
Amgen Inc |
inibidores de kras g12c e métodos de uso dos mesmos
|
MX2019010295A
(es)
|
2017-03-01 |
2019-11-21 |
Genentech Inc |
Métodos de diagnóstico y terapéuticos para el cáncer.
|
AU2018250875A1
(en)
|
2017-04-13 |
2019-10-03 |
F. Hoffmann-La Roche Ag |
An interleukin-2 immunoconjugate, a CD40 agonist, and optionally a PD-1 axis binding antagonist for use in methods of treating cancer
|
JOP20190272A1
(ar)
|
2017-05-22 |
2019-11-21 |
Amgen Inc |
مثبطات kras g12c وطرق لاستخدامها
|
AU2018304458B2
(en)
|
2017-07-21 |
2021-12-09 |
Foundation Medicine, Inc. |
Therapeutic and diagnostic methods for cancer
|
MX2020000903A
(es)
|
2017-08-11 |
2020-07-22 |
Genentech Inc |
Anticuerpos anti-cd8 y usos de los mismos.
|
IL293443A
(en)
|
2017-09-08 |
2022-07-01 |
Amgen Inc |
kras g12c inhibitors and methods of using them
|
EP3679159A1
(de)
|
2017-09-08 |
2020-07-15 |
H. Hoffnabb-La Roche Ag |
Diagnose- und therapieverfahren für krebs
|
CA3073421A1
(en)
|
2017-09-26 |
2019-04-04 |
Daniel Mark COREY |
Chimeric engulfment receptor molecules and methods of use
|
WO2019083960A1
(en)
|
2017-10-24 |
2019-05-02 |
Oncopep, Inc. |
PEPTIDE VACCINES AND HDAC INHIBITORS FOR THE TREATMENT OF MULTIPLE MYELOMA
|
JP2021500409A
(ja)
|
2017-10-24 |
2021-01-07 |
オンコペップ, インコーポレイテッド |
乳がんを処置するためのペプチドワクチンおよびペムブロリズマブ
|
MX2020004567A
(es)
|
2017-11-06 |
2020-08-13 |
Genentech Inc |
Metodos diagnosticos y terapeuticos para el cancer.
|
JP7254076B2
(ja)
|
2017-11-19 |
2023-04-07 |
サンシャイン・レイク・ファーマ・カンパニー・リミテッド |
置換ヘテロアリール化合物及び使用方法
|
EP3730483B1
(de)
|
2017-12-21 |
2023-08-30 |
Hefei Institutes of Physical Science, Chinese Academy of Sciences |
Klasse von pyrimidinderivaten als kinaseinhibitoren
|
AU2019209960B2
(en)
|
2018-01-20 |
2023-11-23 |
Sunshine Lake Pharma Co., Ltd. |
Substituted aminopyrimidine compounds and methods of use
|
US20200399376A1
(en)
|
2018-02-26 |
2020-12-24 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
EP3774804A1
(de)
|
2018-03-26 |
2021-02-17 |
Novartis AG |
N-(3-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)benzamid-derivate
|
WO2019186358A1
(en)
|
2018-03-26 |
2019-10-03 |
Novartis Ag |
3-hydroxy-n-(3-(7h-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)pyrrolidine-1-carboxamide derivatives
|
CA3093969A1
(en)
|
2018-03-28 |
2019-10-03 |
Cero Therapeutics, Inc. |
Expression vectors for chimeric engulfment receptors, genetically modified host cells, and uses thereof
|
RU2020135107A
(ru)
|
2018-03-28 |
2022-04-29 |
Серо Терапьютикс, Инк. |
Клеточные иммунотерапевтические композиции и их применения
|
WO2019191334A1
(en)
|
2018-03-28 |
2019-10-03 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
CA3099118A1
(en)
|
2018-05-04 |
2019-11-07 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
WO2019213516A1
(en)
|
2018-05-04 |
2019-11-07 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
CA3099045A1
(en)
|
2018-05-10 |
2019-11-14 |
Amgen Inc. |
Kras g12c inhibitors for the treatment of cancer
|
AU2019275404A1
(en)
|
2018-05-21 |
2020-12-03 |
Nanostring Technologies, Inc. |
Molecular gene signatures and methods of using same
|
US11096939B2
(en)
|
2018-06-01 |
2021-08-24 |
Amgen Inc. |
KRAS G12C inhibitors and methods of using the same
|
AU2019284472A1
(en)
|
2018-06-11 |
2020-11-26 |
Amgen Inc. |
KRAS G12C inhibitors for treating cancer
|
WO2020050890A2
(en)
|
2018-06-12 |
2020-03-12 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
BR112020026384A2
(pt)
|
2018-06-23 |
2021-03-30 |
Genentech, Inc. |
Métodos para tratar um indivíduo com câncer de pulmão e para tratar um indivíduo com câncer de pulmão de pequenas células, kits, anticorpo anti-pd-l1 e composição
|
CA3104147A1
(en)
|
2018-07-18 |
2020-01-23 |
Genentech, Inc. |
Methods of treating lung cancer with a pd-1 axis binding antagonist, an antimetabolite, and a platinum agent
|
EP3826988A4
(de)
|
2018-07-24 |
2023-03-22 |
Hygia Pharmaceuticals, LLC |
Verbindungen, derivate und analoga für krebs
|
WO2020051099A1
(en)
|
2018-09-03 |
2020-03-12 |
Genentech, Inc. |
Carboxamide and sulfonamide derivatives useful as tead modulators
|
WO2020061060A1
(en)
|
2018-09-19 |
2020-03-26 |
Genentech, Inc. |
Therapeutic and diagnostic methods for bladder cancer
|
EP4249917A3
(de)
|
2018-09-21 |
2023-11-08 |
F. Hoffmann-La Roche AG |
Diagnosemethoden für dreifach-negativen brustkrebs
|
CN113194954A
(zh)
|
2018-10-04 |
2021-07-30 |
国家医疗保健研究所 |
用于治疗角皮病的egfr抑制剂
|
EP3867646A1
(de)
|
2018-10-18 |
2021-08-25 |
F. Hoffmann-La Roche AG |
Diagnostische und therapeutische verfahren für sarkomatoiden nierenkrebs
|
JP2020090482A
(ja)
|
2018-11-16 |
2020-06-11 |
アムジエン・インコーポレーテツド |
Kras g12c阻害剤化合物の重要な中間体の改良合成法
|
WO2020106640A1
(en)
|
2018-11-19 |
2020-05-28 |
Amgen Inc. |
Kras g12c inhibitors and methods of using the same
|
JP7377679B2
(ja)
|
2018-11-19 |
2023-11-10 |
アムジエン・インコーポレーテツド |
がん治療のためのkrasg12c阻害剤及び1種以上の薬学的に活性な追加の薬剤を含む併用療法
|
EP3898626A1
(de)
|
2018-12-19 |
2021-10-27 |
Array Biopharma, Inc. |
Substituierte pyrazolo[1,5-a]pyridin-verbindungen als inhibitoren von fgfr-tyrosinkinasen
|
WO2020131674A1
(en)
|
2018-12-19 |
2020-06-25 |
Array Biopharma Inc. |
7-((3,5-dimethoxyphenyl)amino)quinoxaline derivatives as fgfr inhibitors for treating cancer
|
MX2021007158A
(es)
|
2018-12-20 |
2021-08-16 |
Amgen Inc |
Heteroarilamidas utiles como inhibidores de kif18a.
|
TW202034924A
(zh)
|
2018-12-20 |
2020-10-01 |
美商安進公司 |
Kif18a 抑制劑
|
US20220002311A1
(en)
|
2018-12-20 |
2022-01-06 |
Amgen Inc. |
Kif18a inhibitors
|
WO2020132651A1
(en)
|
2018-12-20 |
2020-06-25 |
Amgen Inc. |
Kif18a inhibitors
|
AR117472A1
(es)
|
2018-12-21 |
2021-08-11 |
Celgene Corp |
Inhibidores de tienopiridina de ripk2
|
CN113396230A
(zh)
|
2019-02-08 |
2021-09-14 |
豪夫迈·罗氏有限公司 |
癌症的诊断和治疗方法
|
US20220146495A1
(en)
|
2019-02-27 |
2022-05-12 |
Epiaxis Therapeutics Pty Ltd |
Methods and agents for assessing t-cell function and predicting response to therapy
|
JP2022521773A
(ja)
|
2019-02-27 |
2022-04-12 |
ジェネンテック, インコーポレイテッド |
抗tigit抗体と抗cd20抗体又は抗cd38抗体とによる処置のための投薬
|
EP3931195A1
(de)
|
2019-03-01 |
2022-01-05 |
Revolution Medicines, Inc. |
Bicyclische heteroarylverbindungen und verwendungen davon
|
KR20210146288A
(ko)
|
2019-03-01 |
2021-12-03 |
레볼루션 메디슨즈, 인크. |
이환식 헤테로사이클릴 화합물 및 이의 용도
|
WO2020223233A1
(en)
|
2019-04-30 |
2020-11-05 |
Genentech, Inc. |
Prognostic and therapeutic methods for colorectal cancer
|
EP3962947A2
(de)
|
2019-05-03 |
2022-03-09 |
F. Hoffmann-La Roche AG |
Verfahren zur behandlung von krebs mit einem anti-pd-l1-antikörper
|
WO2020231990A1
(en)
|
2019-05-13 |
2020-11-19 |
Relay Therapeutics, Inc. |
Fgfr inhibitors and methods of use thereof
|
EP3738593A1
(de)
|
2019-05-14 |
2020-11-18 |
Amgen, Inc |
Dosierung von kras-inhibitor zur behandlung von krebserkrankungen
|
JOP20210310A1
(ar)
|
2019-05-21 |
2023-01-30 |
Amgen Inc |
أشكال الحالة الصلبة
|
CN112300279A
(zh)
|
2019-07-26 |
2021-02-02 |
上海复宏汉霖生物技术股份有限公司 |
针对抗cd73抗体和变体的方法和组合物
|
CN114401953A
(zh)
|
2019-08-02 |
2022-04-26 |
美国安进公司 |
Kif18a抑制剂
|
MX2022001302A
(es)
|
2019-08-02 |
2022-03-02 |
Amgen Inc |
Inhibidores de kif18a.
|
MX2022001295A
(es)
|
2019-08-02 |
2022-02-22 |
Amgen Inc |
Inhibidores de kif18a.
|
MX2022001181A
(es)
|
2019-08-02 |
2022-02-22 |
Amgen Inc |
Inhibidores de kif18a.
|
TW202124439A
(zh)
|
2019-09-04 |
2021-07-01 |
美商建南德克公司 |
Cd8結合劑及其用途
|
JP2022548978A
(ja)
|
2019-09-27 |
2022-11-22 |
ジェネンテック, インコーポレイテッド |
薬抗tigit及び抗pd-l1アンタゴニスト抗体を用いた処置のための投薬
|
EP4038097A1
(de)
|
2019-10-03 |
2022-08-10 |
Cero Therapeutics, Inc. |
Chimäre tim4-rezeptoren und verwendungen davon
|
MX2022004656A
(es)
|
2019-10-24 |
2022-05-25 |
Amgen Inc |
Derivados de piridopirimidina utiles como inhibidores de kras g12c y kras g12d en el tratamiento del cancer.
|
CN114728936A
(zh)
|
2019-10-29 |
2022-07-08 |
豪夫迈·罗氏有限公司 |
用于治疗癌症的双功能化合物
|
US11739074B2
(en)
|
2019-11-04 |
2023-08-29 |
Revolution Medicines, Inc. |
Ras inhibitors
|
AU2020379734A1
(en)
|
2019-11-04 |
2022-05-05 |
Revolution Medicines, Inc. |
Ras inhibitors
|
CA3160142A1
(en)
|
2019-11-04 |
2021-05-14 |
Revolution Medicines, Inc. |
Ras inhibitors
|
MX2022005400A
(es)
|
2019-11-06 |
2022-05-24 |
Genentech Inc |
Metodos de diagnostico y terapeuticos para el tratamiento de canceres hematologicos.
|
AU2020380315A1
(en)
|
2019-11-08 |
2022-05-26 |
Revolution Medicines, Inc. |
Bicyclic heteroaryl compounds and uses thereof
|
CA3155989A1
(en)
|
2019-11-13 |
2021-05-20 |
Jason Robert ZBIEG |
Therapeutic compounds and methods of use
|
CN114728960A
(zh)
|
2019-11-14 |
2022-07-08 |
美国安进公司 |
Kras g12c抑制剂化合物的改善的合成
|
AU2020383535A1
(en)
|
2019-11-14 |
2022-05-05 |
Amgen Inc. |
Improved synthesis of KRAS G12C inhibitor compound
|
US20220395553A1
(en)
|
2019-11-14 |
2022-12-15 |
Cohbar, Inc. |
Cxcr4 antagonist peptides
|
CN114980976A
(zh)
|
2019-11-27 |
2022-08-30 |
锐新医药公司 |
共价ras抑制剂及其用途
|
AU2020403145A1
(en)
|
2019-12-13 |
2022-07-07 |
Genentech, Inc. |
Anti-Ly6G6D antibodies and methods of use
|
AU2020408562A1
(en)
|
2019-12-20 |
2022-06-23 |
Erasca, Inc. |
Tricyclic pyridones and pyrimidones
|
WO2021142026A1
(en)
|
2020-01-07 |
2021-07-15 |
Revolution Medicines, Inc. |
Shp2 inhibitor dosing and methods of treating cancer
|
WO2021194481A1
(en)
|
2020-03-24 |
2021-09-30 |
Genentech, Inc. |
Dosing for treatment with anti-tigit and anti-pd-l1 antagonist antibodies
|
TW202142230A
(zh)
|
2020-01-27 |
2021-11-16 |
美商建南德克公司 |
用於以抗tigit拮抗體抗體治療癌症之方法
|
WO2021177980A1
(en)
|
2020-03-06 |
2021-09-10 |
Genentech, Inc. |
Combination therapy for cancer comprising pd-1 axis binding antagonist and il6 antagonist
|
WO2021233534A1
(en)
|
2020-05-20 |
2021-11-25 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
WO2021185844A1
(en)
|
2020-03-16 |
2021-09-23 |
Pvac Medical Technologies Ltd |
Use of substance and pharmaceutical composition thereof, and medical treatments or uses thereof
|
CN115698717A
(zh)
|
2020-04-03 |
2023-02-03 |
基因泰克公司 |
癌症的治疗和诊断方法
|
WO2021222167A1
(en)
|
2020-04-28 |
2021-11-04 |
Genentech, Inc. |
Methods and compositions for non-small cell lung cancer immunotherapy
|
US11833155B2
(en)
|
2020-06-03 |
2023-12-05 |
Incyte Corporation |
Combination therapy for treatment of myeloproliferative neoplasms
|
KR20230025691A
(ko)
|
2020-06-16 |
2023-02-22 |
제넨테크, 인크. |
삼중 음성 유방암을 치료하기 위한 방법과 조성물
|
WO2021257124A1
(en)
|
2020-06-18 |
2021-12-23 |
Genentech, Inc. |
Treatment with anti-tigit antibodies and pd-1 axis binding antagonists
|
WO2021257736A1
(en)
|
2020-06-18 |
2021-12-23 |
Revolution Medicines, Inc. |
Methods for delaying, preventing, and treating acquired resistance to ras inhibitors
|
US11787775B2
(en)
|
2020-07-24 |
2023-10-17 |
Genentech, Inc. |
Therapeutic compounds and methods of use
|
JP2023536602A
(ja)
|
2020-08-03 |
2023-08-28 |
ジェネンテック, インコーポレイテッド |
リンパ腫のための診断及び治療方法
|
JP2023536346A
(ja)
|
2020-08-05 |
2023-08-24 |
エリプシーズ ファーマ リミテッド |
シクロデキストリン含有ポリマートポイソメラーゼ阻害剤コンジュゲートおよびparp阻害剤を用いた癌の処置
|
WO2022036146A1
(en)
|
2020-08-12 |
2022-02-17 |
Genentech, Inc. |
Diagnostic and therapeutic methods for cancer
|
WO2022036285A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Compositions and methods for treating cancer with chimeric tim receptors in combination with inhibitors of poly (adp-ribose) polymerase
|
WO2022036265A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Chimeric tim receptors and uses thereof
|
WO2022036287A1
(en)
|
2020-08-14 |
2022-02-17 |
Cero Therapeutics, Inc. |
Anti-cd72 chimeric receptors and uses thereof
|
CN116209438A
(zh)
|
2020-09-03 |
2023-06-02 |
锐新医药公司 |
使用sos1抑制剂治疗具有shp2突变的恶性疾病
|
CN116457358A
(zh)
|
2020-09-15 |
2023-07-18 |
锐新医药公司 |
作为ras抑制剂以治疗癌症的吲哚衍生物
|
MX2023003338A
(es)
|
2020-09-23 |
2023-06-14 |
Erasca Inc |
Piridonas y pirimidonas tricíclicas.
|
EP4221753A1
(de)
*
|
2020-10-02 |
2023-08-09 |
Mitokinin, Inc. |
Zusammensetzungen und verfahren zur behandlung von nierenerkrankung und fibrose
|
CA3193952A1
(en)
|
2020-10-05 |
2022-04-14 |
Bernard Martin Fine |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
TW202237638A
(zh)
|
2020-12-09 |
2022-10-01 |
日商武田藥品工業股份有限公司 |
烏苷酸環化酶c(gcc)抗原結合劑之組成物及其使用方法
|
US20230107642A1
(en)
|
2020-12-18 |
2023-04-06 |
Erasca, Inc. |
Tricyclic pyridones and pyrimidones
|
CA3203111A1
(en)
|
2020-12-22 |
2022-06-30 |
Kailiang Wang |
Sos1 inhibitors and uses thereof
|
AU2022221124A1
(en)
|
2021-02-12 |
2023-08-03 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydroazepine derivatives for the treatment of cancer
|
IL305411A
(en)
|
2021-02-26 |
2023-10-01 |
Kelonia Therapeutics Inc |
Lymphocyte-targeted lentiviral vectors
|
EP4334324A1
(de)
|
2021-05-05 |
2024-03-13 |
Revolution Medicines, Inc. |
Kovalente ras-inhibitoren und verwendungen davon
|
WO2022235870A1
(en)
|
2021-05-05 |
2022-11-10 |
Revolution Medicines, Inc. |
Ras inhibitors for the treatment of cancer
|
EP4334321A1
(de)
|
2021-05-05 |
2024-03-13 |
Revolution Medicines, Inc. |
Ras-inhibitoren
|
KR20240026948A
(ko)
|
2021-05-25 |
2024-02-29 |
에라스카, 아이엔씨. |
황 함유 헤테로방향족 트리사이클릭 kras 억제제
|
WO2022266206A1
(en)
|
2021-06-16 |
2022-12-22 |
Erasca, Inc. |
Kras inhibitor conjugates
|
WO2023010097A1
(en)
|
2021-07-28 |
2023-02-02 |
Cero Therapeutics, Inc. |
Chimeric tim4 receptors and uses thereof
|
TW202321261A
(zh)
|
2021-08-10 |
2023-06-01 |
美商伊瑞斯卡公司 |
選擇性kras抑制劑
|
AR127308A1
(es)
|
2021-10-08 |
2024-01-10 |
Revolution Medicines Inc |
Inhibidores ras
|
WO2023097195A1
(en)
|
2021-11-24 |
2023-06-01 |
Genentech, Inc. |
Therapeutic indazole compounds and methods of use in the treatment of cancer
|
TW202340212A
(zh)
|
2021-11-24 |
2023-10-16 |
美商建南德克公司 |
治療性化合物及其使用方法
|
WO2023114954A1
(en)
|
2021-12-17 |
2023-06-22 |
Genzyme Corporation |
Pyrazolopyrazine compounds as shp2 inhibitors
|
EP4227307A1
(de)
|
2022-02-11 |
2023-08-16 |
Genzyme Corporation |
Pyrazolopyrazinverbindungen als shp2-inhibitoren
|
WO2023172940A1
(en)
|
2022-03-08 |
2023-09-14 |
Revolution Medicines, Inc. |
Methods for treating immune refractory lung cancer
|
WO2023191816A1
(en)
|
2022-04-01 |
2023-10-05 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2023219613A1
(en)
|
2022-05-11 |
2023-11-16 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2023240058A2
(en)
|
2022-06-07 |
2023-12-14 |
Genentech, Inc. |
Prognostic and therapeutic methods for cancer
|
WO2023240263A1
(en)
|
2022-06-10 |
2023-12-14 |
Revolution Medicines, Inc. |
Macrocyclic ras inhibitors
|
WO2024015897A1
(en)
|
2022-07-13 |
2024-01-18 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024020432A1
(en)
|
2022-07-19 |
2024-01-25 |
Genentech, Inc. |
Dosing for treatment with anti-fcrh5/anti-cd3 bispecific antibodies
|
WO2024030441A1
(en)
|
2022-08-02 |
2024-02-08 |
National University Corporation Hokkaido University |
Methods of improving cellular therapy with organelle complexes
|
WO2024033388A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024033458A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydroazepine derivatives
|
WO2024033389A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024033457A1
(en)
|
2022-08-11 |
2024-02-15 |
F. Hoffmann-La Roche Ag |
Bicyclic tetrahydrothiazepine derivatives
|
WO2024041440A1
(en)
*
|
2022-08-24 |
2024-02-29 |
Danatlas Pharmaceuticals Co., Ltd. |
Tricyclic heterocyclic derivatives, compositions and uses thereof
|
US11945823B1
(en)
|
2023-09-14 |
2024-04-02 |
King Faisal University |
Substituted pyrrolo[2,3-d]pyrimidines as CK2 inhibitors
|