MA51552A - Anticorps anti-ox40 et procédés d'utilisation - Google Patents
Anticorps anti-ox40 et procédés d'utilisationInfo
- Publication number
- MA51552A MA51552A MA051552A MA51552A MA51552A MA 51552 A MA51552 A MA 51552A MA 051552 A MA051552 A MA 051552A MA 51552 A MA51552 A MA 51552A MA 51552 A MA51552 A MA 51552A
- Authority
- MA
- Morocco
- Prior art keywords
- antibodies
- methods
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
- C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201461973193P | 2014-03-31 | 2014-03-31 | |
US201461989448P | 2014-05-06 | 2014-05-06 | |
US201462073873P | 2014-10-31 | 2014-10-31 | |
US201462080171P | 2014-11-14 | 2014-11-14 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA51552A true MA51552A (fr) | 2021-03-24 |
Family
ID=52829446
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA40682A MA40682B1 (fr) | 2014-03-31 | 2015-03-30 | Anticorps anti-ox40 et procédés d'utilisation correspondants |
MA051552A MA51552A (fr) | 2014-03-31 | 2015-03-30 | Anticorps anti-ox40 et procédés d'utilisation |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA40682A MA40682B1 (fr) | 2014-03-31 | 2015-03-30 | Anticorps anti-ox40 et procédés d'utilisation correspondants |
Country Status (29)
Country | Link |
---|---|
EP (2) | EP3632934A1 (fr) |
JP (2) | JP6637439B2 (fr) |
KR (1) | KR20160145624A (fr) |
CN (1) | CN106103486B (fr) |
AU (1) | AU2015241037B2 (fr) |
BR (1) | BR112016022658A2 (fr) |
CA (1) | CA2943262A1 (fr) |
CL (1) | CL2016002462A1 (fr) |
CR (1) | CR20160500A (fr) |
DK (1) | DK3126394T3 (fr) |
EA (1) | EA201691974A1 (fr) |
ES (1) | ES2763898T3 (fr) |
HR (1) | HRP20192285T1 (fr) |
HU (1) | HUE046767T2 (fr) |
IL (1) | IL247898A0 (fr) |
LT (1) | LT3126394T (fr) |
MA (2) | MA40682B1 (fr) |
MX (1) | MX2016012781A (fr) |
PE (2) | PE20161571A1 (fr) |
PH (1) | PH12016501894B1 (fr) |
PL (1) | PL3126394T3 (fr) |
PT (1) | PT3126394T (fr) |
RS (1) | RS59738B1 (fr) |
SG (1) | SG11201607969XA (fr) |
SI (1) | SI3126394T1 (fr) |
TW (1) | TWI680985B (fr) |
UA (1) | UA121112C2 (fr) |
WO (1) | WO2015153513A1 (fr) |
ZA (1) | ZA201606630B (fr) |
Families Citing this family (82)
Publication number | Priority date | Publication date | Assignee | Title |
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EP1539228B1 (fr) | 2002-09-11 | 2010-12-29 | Genentech, Inc. | Nouvelles composition et methodes servant au traitement de maladies associees au systeme immunitaire |
KR101924831B1 (ko) | 2008-04-09 | 2018-12-05 | 제넨테크, 인크. | 면역 관련 질병의 치료를 위한 신규한 조성물 및 방법 |
LT2976361T (lt) | 2013-03-18 | 2018-10-25 | Biocerox Products B.V. | Humanizuoti antikūnai prieš receptorių cd134 (ox40) ir jų naudojimas |
KR20160030936A (ko) | 2013-07-16 | 2016-03-21 | 제넨테크, 인크. | Pd-1 축 결합 길항제 및 tigit 억제제를 사용한 암을 치료하는 방법 |
CN106132439A (zh) | 2014-03-31 | 2016-11-16 | 豪夫迈·罗氏有限公司 | 包含抗血管发生剂和ox40结合激动剂的组合疗法 |
SG11201703521UA (en) | 2014-11-03 | 2017-05-30 | Genentech Inc | Methods and biomarkers for predicting efficacy and evaluation of an ox40 agonist treatment |
BR112017009151A2 (pt) | 2014-11-03 | 2018-03-06 | Genentech, Inc. | ensaios para detectar subgrupos imunológicos de célula t e métodos de uso dos mesmos |
KR20170072343A (ko) * | 2014-11-06 | 2017-06-26 | 제넨테크, 인크. | Ox40 결합 효능제 및 tigit 억제제를 포함하는 병용 요법 |
MX2017014188A (es) | 2015-05-07 | 2018-04-10 | Agenus Inc | Anticuerpos anti-ox40 y metodos para su uso. |
PL3303396T3 (pl) | 2015-05-29 | 2023-03-06 | Bristol-Myers Squibb Company | Przeciwciała przeciwko ox40 i ich zastosowanie |
WO2016200836A1 (fr) * | 2015-06-08 | 2016-12-15 | Genentech, Inc. | Méthodes de traitement du cancer au moyen d'anticorps anti-ox40 |
KR20230125094A (ko) | 2015-09-25 | 2023-08-28 | 제넨테크, 인크. | 항-tigit 항체 및 이의 이용 방법 |
AU2016329120B2 (en) | 2015-10-02 | 2023-04-13 | F. Hoffmann-La Roche Ag | Bispecific antibodies specific for a costimulatory TNF receptor |
WO2017063162A1 (fr) * | 2015-10-15 | 2017-04-20 | 苏州丁孚靶点生物技术有限公司 | Anticorps anti-ox40 et son application |
MA45488A (fr) | 2015-10-22 | 2018-08-29 | Juno Therapeutics Gmbh | Procédés, kits et appareil de culture de cellules |
SG11201804265XA (en) * | 2015-12-02 | 2018-06-28 | Agenus Inc | Antibodies and methods of use thereof |
WO2017096182A1 (fr) * | 2015-12-03 | 2017-06-08 | Agenus Inc. | Anticorps anti-ox40 et leurs procédés d'utilisation |
DE102016105069A1 (de) * | 2016-03-18 | 2017-09-21 | Eberhard Karls Universität Tübingen Medizinische Fakultät | Antivirale Immuntherapie durch Membranrezeptorligation |
MX2018013683A (es) | 2016-05-10 | 2019-06-17 | Genentech Inc | Métodos para disminuir los enlaces de trisulfuro durante la producción recombinante de polipéptidos. |
TW201803905A (zh) | 2016-06-20 | 2018-02-01 | 克馬伯有限公司 | 用於免疫腫瘤學之多重專一性抗體 |
WO2018027204A1 (fr) * | 2016-08-05 | 2018-02-08 | Genentech, Inc. | Anticorps multivalents et multiépitopiques ayant une activité agoniste et procédés d'utilisation |
US10781260B2 (en) | 2016-08-08 | 2020-09-22 | Sorrento Therapeutics, Inc. | Anti-OX40 binding proteins |
WO2018041119A1 (fr) | 2016-08-31 | 2018-03-08 | Beijing Biocytogen Co., Ltd | Animal non humain génétiquement modifié à ox40 humain ou chimérique |
CN107815465B (zh) | 2016-08-31 | 2021-03-16 | 百奥赛图(北京)医药科技股份有限公司 | 人源化基因改造动物模型的制备方法及应用 |
MA46770A (fr) | 2016-11-09 | 2019-09-18 | Agenus Inc | Anticorps anti-ox40, anticorps anti-gitr, et leurs procédés d'utilisation |
CA3047059A1 (fr) | 2016-12-19 | 2018-06-28 | Glenmark Pharmaceuticals S.A. | Nouveaux agonistes de tnfr et leurs utilisations |
US20190375847A1 (en) | 2017-02-15 | 2019-12-12 | Glaxosmithkline Intellectual Property Development Limited | Combination treatment for cancer |
CN108623686A (zh) | 2017-03-25 | 2018-10-09 | 信达生物制药(苏州)有限公司 | 抗ox40抗体及其用途 |
WO2019089921A1 (fr) | 2017-11-01 | 2019-05-09 | Bristol-Myers Squibb Company | Anticorps agonistes immunostimulateurs destinés à être utilisés dans le traitement du cancer |
WO2019106605A1 (fr) | 2017-12-01 | 2019-06-06 | Board Of Regents, The University Of Texas System | Polythérapie pour le traitement du cancer |
US11142579B2 (en) | 2017-12-06 | 2021-10-12 | Sorrento Therapeutics, Inc. | Variant antibodies that bind OX40 |
CN115925943A (zh) | 2017-12-27 | 2023-04-07 | 信达生物制药(苏州)有限公司 | 抗pd-l1抗体及其用途 |
WO2019129136A1 (fr) | 2017-12-27 | 2019-07-04 | 信达生物制药(苏州)有限公司 | Anticorps anti-pd-l1 et ses applications |
CN109970856B (zh) | 2017-12-27 | 2022-08-23 | 信达生物制药(苏州)有限公司 | 抗lag-3抗体及其用途 |
WO2019129137A1 (fr) | 2017-12-27 | 2019-07-04 | 信达生物制药(苏州)有限公司 | Anticorps anti-lag-3 et utilisations associées |
CN108218990B (zh) * | 2017-12-29 | 2021-03-02 | 南京优迈生物科技有限公司 | 分离的抗体或其抗原结合片段及其在肿瘤治疗中的应用 |
AU2018394939B2 (en) | 2017-12-29 | 2022-02-24 | Ap Biosciences, Inc. | Monospecific and bispecific proteins with immune checkpoint regulation for cancer therapy |
CN110092832B (zh) * | 2018-01-29 | 2020-03-31 | 康源博创生物科技(北京)有限公司 | 抗ox40抗体及其用途 |
TW202003555A (zh) | 2018-03-07 | 2020-01-16 | 英商葛蘭素史克智慧財產發展有限公司 | 用於純化重組多肽之方法 |
PE20210665A1 (es) | 2018-03-23 | 2021-03-31 | Bristol Myers Squibb Co | Anticuerpos contra mica y/o micb y sus usos |
CN111918873A (zh) | 2018-03-27 | 2020-11-10 | 百时美施贵宝公司 | 使用紫外线信号实时监测滴度 |
CN111936625A (zh) | 2018-03-29 | 2020-11-13 | 豪夫迈·罗氏有限公司 | 调节哺乳动物细胞中的生乳活性 |
JP7411575B2 (ja) | 2018-05-11 | 2024-01-11 | ウーシー・バイオロジクス・(シャンハイ)・カンパニー・リミテッド | Ox40に対する完全ヒト抗体、それを調製する方法、およびその使用 |
US20210277135A1 (en) | 2018-07-13 | 2021-09-09 | Bristol-Myers Squibb Company | Ox-40 agonist, pd-1 pathway inhibitor and ctla-4 inhibitor combination for use in a method of treating a cancer or a solid tumor |
KR20210040827A (ko) | 2018-07-25 | 2021-04-14 | 이노벤트 바이오로직스 (쑤저우) 컴퍼니, 리미티드 | 항 tigit 항체 및 그 용도 |
JP2022502417A (ja) | 2018-09-26 | 2022-01-11 | 江蘇恒瑞医薬股▲ふん▼有限公司 | 抗ox40抗体、その抗原結合フラグメント、および医薬用途 |
EP3889180A4 (fr) * | 2018-11-26 | 2023-01-04 | Nanjing GenScript Biotech Co., Ltd. | Anticorps monoclonal humanisé anti-ox40, son procédé de préparation et son utilisation |
US20220017632A1 (en) * | 2018-12-25 | 2022-01-20 | Hanx Biopharmaceutics, Inc | Anti-ox40 monoclonal antibody and application thereof |
US10442866B1 (en) | 2019-01-23 | 2019-10-15 | Beijing Mabworks Biotech Co. Ltd | Antibodies binding OX40 and uses thereof |
WO2020172658A1 (fr) | 2019-02-24 | 2020-08-27 | Bristol-Myers Squibb Company | Procédés d'isolement d'une protéine |
WO2020237221A1 (fr) | 2019-05-23 | 2020-11-26 | Bristol-Myers Squibb Company | Méthodes de surveillance de milieu |
US20220233691A1 (en) | 2019-05-30 | 2022-07-28 | Bristol-Myers Squibb Company | Cell localization signature and combination therapy |
WO2020243568A1 (fr) | 2019-05-30 | 2020-12-03 | Bristol-Myers Squibb Company | Procédés d'identification d'un sujet approprié pour une thérapie d'immuno-oncologie (i-o) |
CN114174538A (zh) | 2019-05-30 | 2022-03-11 | 百时美施贵宝公司 | 适合于免疫肿瘤学疗法的多肿瘤基因特征 |
CN110172090B (zh) * | 2019-06-03 | 2020-04-03 | 中山标佳生物科技有限公司 | Cd134单克隆抗体及其制备方法和癌症治疗中的应用 |
CN114040776B (zh) * | 2019-06-28 | 2024-05-14 | 江苏恒瑞医药股份有限公司 | Tlr激动剂与抗ox40抗体或其抗原结合片段联合在制备治疗肿瘤的药物中的用途 |
WO2021098749A1 (fr) * | 2019-11-21 | 2021-05-27 | Beigene (Beijing) Co., Ltd. | Méthodes de traitement du cancer associant un anticorps anti-ox40 et la radiothérapie |
WO2021098777A1 (fr) * | 2019-11-21 | 2021-05-27 | Beigene, Ltd. | Procédés de traitement du cancer utilisant des anticorps anti-ox40 en combinaison avec des inhibiteurs de pi3 kinase delta |
AU2020407208A1 (en) | 2019-12-17 | 2022-06-02 | Amgen Inc. | Dual interleukin-2 /tnf receptor agonist for use in therapy |
WO2021190582A1 (fr) * | 2020-03-25 | 2021-09-30 | 江苏恒瑞医药股份有限公司 | Composition pharmaceutique d'anticorps anti-ox40 et son utilisation |
US20210309989A1 (en) | 2020-03-26 | 2021-10-07 | Genentech, Inc. | Modified mammalian cells |
AR121706A1 (es) | 2020-04-01 | 2022-06-29 | Hoffmann La Roche | Moléculas de unión a antígeno biespecíficas dirigidas a ox40 y fap |
TW202144424A (zh) | 2020-04-17 | 2021-12-01 | 大陸商和記黃埔醫藥(上海)有限公司 | 抗ox40抗體及其用途 |
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JP2023539201A (ja) | 2020-08-28 | 2023-09-13 | ジェネンテック, インコーポレイテッド | 宿主細胞タンパク質のCRISPR/Cas9マルチプレックスノックアウト |
IL300916A (en) | 2020-08-31 | 2023-04-01 | Bristol Myers Squibb Co | Cell localization signature and immunotherapy |
EP4225770A1 (fr) | 2020-10-05 | 2023-08-16 | Bristol-Myers Squibb Company | Procédés pour concentrer des protéines |
WO2022079036A1 (fr) * | 2020-10-13 | 2022-04-21 | Almirall, S.A. | Molécules bispécifiques et procédés de traitement les utilisant |
WO2022120179A1 (fr) | 2020-12-03 | 2022-06-09 | Bristol-Myers Squibb Company | Signatures géniques multi-tumorales et leurs utilisations |
EP4267172A1 (fr) | 2020-12-28 | 2023-11-01 | Bristol-Myers Squibb Company | Administration sous-cutanée d'anticorps pd1/pd-l1 |
IL303648A (en) | 2020-12-28 | 2023-08-01 | Bristol Myers Squibb Co | Antibody preparations and methods of using them |
EP4289865A1 (fr) | 2021-02-04 | 2023-12-13 | Innovent Biologics (Suzhou) Co., Ltd. | Anticorps anti-tnfr2 et son utilisation |
WO2022212876A1 (fr) | 2021-04-02 | 2022-10-06 | The Regents Of The University Of California | Anticorps dirigés contre un cdcp1 clivé et leurs utilisations |
EP4326855A1 (fr) | 2021-04-19 | 2024-02-28 | Genentech, Inc. | Cellules mammifères modifiées |
JP2024521107A (ja) | 2021-05-21 | 2024-05-28 | ジェネンテック, インコーポレイテッド | 目的の組換え産物を産生するための修飾細胞 |
CN115403670A (zh) | 2021-05-26 | 2022-11-29 | 安徽瀚海博兴生物技术有限公司 | 抗cd40抗体及其用途 |
CN115611983A (zh) | 2021-07-14 | 2023-01-17 | 三优生物医药(上海)有限公司 | Cldn18.2结合分子及其用途 |
TW202323280A (zh) * | 2021-10-15 | 2023-06-16 | 新加坡商創響私人有限公司 | 包含抗-ox40單株抗體的藥物製劑 |
WO2023173011A1 (fr) | 2022-03-09 | 2023-09-14 | Bristol-Myers Squibb Company | Expression transitoire de protéines thérapeutiques |
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