EA201691974A1 - Антитела против ox40 и способы их применения - Google Patents

Антитела против ox40 и способы их применения

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Publication number
EA201691974A1
EA201691974A1 EA201691974A EA201691974A EA201691974A1 EA 201691974 A1 EA201691974 A1 EA 201691974A1 EA 201691974 A EA201691974 A EA 201691974A EA 201691974 A EA201691974 A EA 201691974A EA 201691974 A1 EA201691974 A1 EA 201691974A1
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EA
Eurasian Patent Office
Prior art keywords
methods
antibodies against
application
relates
antibodies
Prior art date
Application number
EA201691974A
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English (en)
Inventor
Чанчунь Ду
Дзеонг Ким
Цзин Чжу
Джек Беверс III
Кевин Уолш
Патрисия Де Алмейда
Джеймс Эндья
Е Шэнь
Original Assignee
Дженентек, Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=52829446&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA201691974(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Дженентек, Инк. filed Critical Дженентек, Инк.
Publication of EA201691974A1 publication Critical patent/EA201691974A1/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732—Antibody-dependent cellular cytotoxicity [ADCC]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/94—Stability, e.g. half-life, pH, temperature or enzyme-resistance

Abstract

Данное изобретение относится к антителам против OX40 и способам их применения.
EA201691974A 2014-03-31 2015-03-30 Антитела против ox40 и способы их применения EA201691974A1 (ru)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201461973193P 2014-03-31 2014-03-31
US201461989448P 2014-05-06 2014-05-06
US201462073873P 2014-10-31 2014-10-31
US201462080171P 2014-11-14 2014-11-14
PCT/US2015/023432 WO2015153513A1 (en) 2014-03-31 2015-03-30 Anti-ox40 antibodies and methods of use

Publications (1)

Publication Number Publication Date
EA201691974A1 true EA201691974A1 (ru) 2017-04-28

Family

ID=52829446

Family Applications (1)

Application Number Title Priority Date Filing Date
EA201691974A EA201691974A1 (ru) 2014-03-31 2015-03-30 Антитела против ox40 и способы их применения

Country Status (29)

Country Link
EP (2) EP3632934A1 (ru)
JP (2) JP6637439B2 (ru)
KR (1) KR20160145624A (ru)
CN (1) CN106103486B (ru)
AU (1) AU2015241037B2 (ru)
BR (1) BR112016022658A2 (ru)
CA (1) CA2943262A1 (ru)
CL (1) CL2016002462A1 (ru)
CR (1) CR20160500A (ru)
DK (1) DK3126394T3 (ru)
EA (1) EA201691974A1 (ru)
ES (1) ES2763898T3 (ru)
HR (1) HRP20192285T1 (ru)
HU (1) HUE046767T2 (ru)
IL (1) IL247898A0 (ru)
LT (1) LT3126394T (ru)
MA (2) MA40682B1 (ru)
MX (1) MX2016012781A (ru)
PE (2) PE20161571A1 (ru)
PH (1) PH12016501894B1 (ru)
PL (1) PL3126394T3 (ru)
PT (1) PT3126394T (ru)
RS (1) RS59738B1 (ru)
SG (1) SG11201607969XA (ru)
SI (1) SI3126394T1 (ru)
TW (1) TWI680985B (ru)
UA (1) UA121112C2 (ru)
WO (1) WO2015153513A1 (ru)
ZA (1) ZA201606630B (ru)

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