BRPI0415448A8 - método de alvejar populações de célula específica empregando-se conjugados de maytansinoid de agente de ligação celular ligados por meio de um ligante não-clivável, os referidos conjugados, e métodos de preparação dos referidos conjugados - Google Patents

método de alvejar populações de célula específica empregando-se conjugados de maytansinoid de agente de ligação celular ligados por meio de um ligante não-clivável, os referidos conjugados, e métodos de preparação dos referidos conjugados Download PDF

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Publication number
BRPI0415448A8
BRPI0415448A8 BRPI0415448A BRPI0415448A BRPI0415448A8 BR PI0415448 A8 BRPI0415448 A8 BR PI0415448A8 BR PI0415448 A BRPI0415448 A BR PI0415448A BR PI0415448 A BRPI0415448 A BR PI0415448A BR PI0415448 A8 BRPI0415448 A8 BR PI0415448A8
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BR
Brazil
Prior art keywords
conjugates
preparing
methods
maytansinoid
targeting specific
Prior art date
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BRPI0415448A
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English (en)
Portuguese (pt)
Inventor
Chari Ravi
Steeves Rita
Blattler Walter
Widdison Wayne
Original Assignee
Immunogen Inc
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Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34467962&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0415448(A8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunogen Inc filed Critical Immunogen Inc
Publication of BRPI0415448A publication Critical patent/BRPI0415448A/pt
Publication of BRPI0415448A8 publication Critical patent/BRPI0415448A8/pt

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
    • C—CHEMISTRY; METALLURGY
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BRPI0415448A 2003-10-10 2004-10-12 método de alvejar populações de célula específica empregando-se conjugados de maytansinoid de agente de ligação celular ligados por meio de um ligante não-clivável, os referidos conjugados, e métodos de preparação dos referidos conjugados BRPI0415448A8 (pt)

Applications Claiming Priority (3)

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US50990103P 2003-10-10 2003-10-10
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