AR080301A1 - Anticuerpos e inmunoconjugados del receptor 1 de folato y sus usos - Google Patents

Anticuerpos e inmunoconjugados del receptor 1 de folato y sus usos

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Publication number
AR080301A1
AR080301A1 ARP110100569A AR080301A1 AR 080301 A1 AR080301 A1 AR 080301A1 AR P110100569 A ARP110100569 A AR P110100569A AR 080301 A1 AR080301 A1 AR 080301A1
Authority
AR
Argentina
Prior art keywords
num
sec
ident
antibodies
immunoconjugados
Prior art date
Application number
Other languages
English (en)
Original Assignee
Immunogen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immunogen Inc filed Critical Immunogen Inc
Publication of AR080301A1 publication Critical patent/AR080301A1/es

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    • C—CHEMISTRY; METALLURGY
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    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/537—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines spiro-condensed or forming part of bridged ring systems
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Abstract

Se proporcionan agentes contra el cáncer, que incluyen, pero sin limitarse a, anticuerpos e inmunoconjugados, que se unen al receptor 1 de folato humano. Los métodos de usar los agentes, anticuerpos, o inmunoconjugados, tales como los métodos de inhibir el crecimiento se proporcionan también. Reivindicacion 1: Un agente de union al receptor 1 de folato humano que comprende una secuencia de aminoácido seleccionada del grupo consistente de sec. con num. ident. :4, sec. con num. ident.:42, sec. con num. ident.:97, sec. con num. ident.:99, sec. con num. ident.:101, y sec. con num. ident.:103.
ARP110100569 2010-02-24 2011-02-24 Anticuerpos e inmunoconjugados del receptor 1 de folato y sus usos AR080301A1 (es)

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