PT865293E - Bloqueio da regulação negativa dos linfócitos t associada à sinalização por ctla-4 - Google Patents

Bloqueio da regulação negativa dos linfócitos t associada à sinalização por ctla-4 Download PDF

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Publication number
PT865293E
PT865293E PT96942901T PT96942901T PT865293E PT 865293 E PT865293 E PT 865293E PT 96942901 T PT96942901 T PT 96942901T PT 96942901 T PT96942901 T PT 96942901T PT 865293 E PT865293 E PT 865293E
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PT
Portugal
Prior art keywords
ctla
cells
antibody
cell
tumor
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PT96942901T
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English (en)
Portuguese (pt)
Inventor
James Patrick Allison
Dana R Leach
Matthew F Krummel
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Univ California
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27074292&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT865293(E) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/566,853 external-priority patent/US5855887A/en
Application filed by Univ California filed Critical Univ California
Publication of PT865293E publication Critical patent/PT865293E/pt

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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/70521CD28, CD152
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P13/00Drugs for disorders of the urinary system
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
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    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55522Cytokines; Lymphokines; Interferons
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S424/00Drug, bio-affecting and body treating compositions
    • Y10S424/81Drug, bio-affecting and body treating compositions involving autoimmunity, allergy, immediate hypersensitivity, delayed hypersensitivity, immunosuppression, immunotolerance, or anergy

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  • Gastroenterology & Hepatology (AREA)
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  • Microbiology (AREA)
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  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
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  • Cell Biology (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Virology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Radiation-Therapy Devices (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
PT96942901T 1995-12-04 1996-12-04 Bloqueio da regulação negativa dos linfócitos t associada à sinalização por ctla-4 PT865293E (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/566,853 US5855887A (en) 1995-07-25 1995-12-04 Blockade of lymphocyte down-regulation associated with CTLA-4 signaling
US08/646,605 US5811097A (en) 1995-07-25 1996-05-08 Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling

Publications (1)

Publication Number Publication Date
PT865293E true PT865293E (pt) 2009-03-06

Family

ID=27074292

Family Applications (2)

Application Number Title Priority Date Filing Date
PT101800324T PT2332561E (pt) 1995-12-04 1996-12-04 Utilização combinada de agente de bloqueio de ctla-4 e terapia linfotóxica no tratamento de tumores
PT96942901T PT865293E (pt) 1995-12-04 1996-12-04 Bloqueio da regulação negativa dos linfócitos t associada à sinalização por ctla-4

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PT101800324T PT2332561E (pt) 1995-12-04 1996-12-04 Utilização combinada de agente de bloqueio de ctla-4 e terapia linfotóxica no tratamento de tumores

Country Status (12)

Country Link
US (1) US5811097A (enExample)
EP (3) EP0865293B1 (enExample)
JP (2) JP4477701B2 (enExample)
AT (1) ATE415172T1 (enExample)
AU (1) AU730500B2 (enExample)
CA (2) CA2239448C (enExample)
DE (2) DE69637762D1 (enExample)
DK (2) DK2332561T3 (enExample)
ES (2) ES2579277T3 (enExample)
LU (1) LU91927I2 (enExample)
PT (2) PT2332561E (enExample)
WO (1) WO1997020574A1 (enExample)

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