AU4158396A - Methods for inhibiting graft versus host disease in bone marrow transplantation - Google Patents

Methods for inhibiting graft versus host disease in bone marrow transplantation

Info

Publication number
AU4158396A
AU4158396A AU41583/96A AU4158396A AU4158396A AU 4158396 A AU4158396 A AU 4158396A AU 41583/96 A AU41583/96 A AU 41583/96A AU 4158396 A AU4158396 A AU 4158396A AU 4158396 A AU4158396 A AU 4158396A
Authority
AU
Australia
Prior art keywords
methods
bone marrow
host disease
versus host
graft versus
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU41583/96A
Inventor
Gary S. Gray
John G Gribben
Lee M Nadler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Repligen Corp
Dana Farber Cancer Institute Inc
Original Assignee
Repligen Corp
Dana Farber Cancer Institute Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Repligen Corp, Dana Farber Cancer Institute Inc filed Critical Repligen Corp
Publication of AU4158396A publication Critical patent/AU4158396A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/1774—Immunoglobulin superfamily (e.g. CD2, CD4, CD8, ICAM molecules, B7 molecules, Fc-receptors, MHC-molecules)

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AU41583/96A 1994-11-10 1995-11-09 Methods for inhibiting graft versus host disease in bone marrow transplantation Abandoned AU4158396A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33796094A 1994-11-10 1994-11-10
US337960 1994-11-10
PCT/US1995/014774 WO1996014865A1 (en) 1994-11-10 1995-11-09 Methods for inhibiting graft versus host disease in bone marrow transplantation

Publications (1)

Publication Number Publication Date
AU4158396A true AU4158396A (en) 1996-06-06

Family

ID=23322778

Family Applications (1)

Application Number Title Priority Date Filing Date
AU41583/96A Abandoned AU4158396A (en) 1994-11-10 1995-11-09 Methods for inhibiting graft versus host disease in bone marrow transplantation

Country Status (2)

Country Link
AU (1) AU4158396A (en)
WO (1) WO1996014865A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6887471B1 (en) 1991-06-27 2005-05-03 Bristol-Myers Squibb Company Method to inhibit T cell interactions with soluble B7
US5397703A (en) * 1992-07-09 1995-03-14 Cetus Oncology Corporation Method for generation of antibodies to cell surface molecules
US5811097A (en) * 1995-07-25 1998-09-22 The Regents Of The University Of California Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
US6051227A (en) 1995-07-25 2000-04-18 The Regents Of The University Of California, Office Of Technology Transfer Blockade of T lymphocyte down-regulation associated with CTLA-4 signaling
US5855887A (en) * 1995-07-25 1999-01-05 The Regents Of The University Of California Blockade of lymphocyte down-regulation associated with CTLA-4 signaling
CA2194814A1 (en) 1997-01-10 1998-07-10 Terry L. Delovitch Stimulation of protective t cells to prevent autoimmune disease
AU8800598A (en) * 1997-06-20 1999-01-04 Innogenetics N.V. B7-binding molecules for treating immune diseases
MXPA01008098A (en) 1999-02-12 2002-10-23 Inst Genetics Llc Humanized immunoglobulin reactive with b7 molecules and methods of treatment therewith.
US6972125B2 (en) 1999-02-12 2005-12-06 Genetics Institute, Llc Humanized immunoglobulin reactive with B7-2 and methods of treatment therewith
US7605238B2 (en) 1999-08-24 2009-10-20 Medarex, Inc. Human CTLA-4 antibodies and their uses
US7094874B2 (en) 2000-05-26 2006-08-22 Bristol-Myers Squibb Co. Soluble CTLA4 mutant molecules
US20040022787A1 (en) 2000-07-03 2004-02-05 Robert Cohen Methods for treating an autoimmune disease using a soluble CTLA4 molecule and a DMARD or NSAID
SI1935427T1 (en) 2000-07-03 2018-05-31 Bristol-Myers Squibb Company Uses of soluble CTLA4 mutant molecules
PT1397153E (en) 2001-05-23 2008-06-12 Bristol Myers Squibb Co Methods for protecting allogeneic islet transplant using soluble ctla4 mutant molecules
DE10131971A1 (en) * 2001-07-02 2003-01-30 Cytonet Gmbh & Co Kg Preparation of hematopoietic stem cell preparations, useful in transplants for treating leukemia and viral infections, does not induce graft versus host disease
NZ568016A (en) 2005-12-07 2011-12-22 Medarex Inc CTLA-4 antibody dosage escalation regimens
WO2020172391A1 (en) * 2019-02-22 2020-08-27 The Children's Medical Center Methods and compositions relating to the treatment of gvhd

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09500788A (en) * 1993-07-26 1997-01-28 ダナ・ファーバー・キャンサー・インスティテュート・インコーポレイテッド B7-2: CTLA4 / CD28 counter receptor
AU2701895A (en) * 1994-06-07 1996-01-05 Regents Of The University Of Minnesota Methods for inhibiting antigen specific t cell responses

Also Published As

Publication number Publication date
WO1996014865A1 (en) 1996-05-23

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