PE20110426A1 - Polipeptidos g-csf bovinos modificados - Google Patents

Polipeptidos g-csf bovinos modificados

Info

Publication number
PE20110426A1
PE20110426A1 PE2011000065A PE2011000065A PE20110426A1 PE 20110426 A1 PE20110426 A1 PE 20110426A1 PE 2011000065 A PE2011000065 A PE 2011000065A PE 2011000065 A PE2011000065 A PE 2011000065A PE 20110426 A1 PE20110426 A1 PE 20110426A1
Authority
PE
Peru
Prior art keywords
polypeptide
csf
substitute
hydrazide
refers
Prior art date
Application number
PE2011000065A
Other languages
English (en)
Spanish (es)
Inventor
Putnam Anna-Maria A Hays
Nick Knudsen
Thea Norman
Vadim Kraynov
Lillian Ho
Peter Connor Canning
Alan Koder
Original Assignee
Ambrx Inc
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambrx Inc, Lilly Co Eli filed Critical Ambrx Inc
Publication of PE20110426A1 publication Critical patent/PE20110426A1/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/16Central respiratory analeptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/04Immunostimulants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/193Colony stimulating factors [CSF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyamides (AREA)
PE2011000065A 2008-07-23 2009-07-22 Polipeptidos g-csf bovinos modificados PE20110426A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8313208P 2008-07-23 2008-07-23

Publications (1)

Publication Number Publication Date
PE20110426A1 true PE20110426A1 (es) 2011-07-01

Family

ID=41570844

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2011000065A PE20110426A1 (es) 2008-07-23 2009-07-22 Polipeptidos g-csf bovinos modificados

Country Status (23)

Country Link
US (3) US10138283B2 (enExample)
EP (2) EP3225248B1 (enExample)
JP (2) JP5680534B2 (enExample)
KR (1) KR101726884B1 (enExample)
CN (2) CN106928339A (enExample)
AR (1) AR072967A1 (enExample)
AU (1) AU2009274076C1 (enExample)
BR (1) BRPI0916515B8 (enExample)
CA (1) CA2729851C (enExample)
CL (1) CL2011000013A1 (enExample)
CO (1) CO6351745A2 (enExample)
EA (1) EA019968B1 (enExample)
ES (2) ES2963062T3 (enExample)
IL (1) IL210265A (enExample)
MX (1) MX2011000859A (enExample)
NZ (2) NZ591235A (enExample)
PA (1) PA8836801A1 (enExample)
PE (1) PE20110426A1 (enExample)
PL (2) PL3225248T3 (enExample)
PT (1) PT2318029T (enExample)
UA (2) UA103774C2 (enExample)
WO (1) WO2010011735A2 (enExample)
ZA (1) ZA201101166B (enExample)

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BRPI0919403A2 (pt) 2008-09-26 2017-09-26 Ambrx Inc polipeptídeos modificados de eritropoetina animal e seus usos
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KR101963460B1 (ko) 2010-08-17 2019-03-28 암브룩스, 인코포레이티드 변형된 릴랙신 폴리펩타이드 및 그것의 용도
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
CN102380090A (zh) * 2010-08-31 2012-03-21 健能隆医药技术(上海)有限公司 G-csf二聚体在治疗嗜中性粒细胞减少症中的应用
AR083006A1 (es) 2010-09-23 2013-01-23 Lilly Co Eli Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
US9642917B2 (en) 2011-07-25 2017-05-09 Generon (Shanghai) Corporation, Ltd. Use of G-CSF dimer in preparation of medicament for treatment of neurodegenerative diseases
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WO2013130917A1 (en) * 2012-02-29 2013-09-06 Ambrx, Inc. Interleukin-3 polypeptide conjugates their uses
CN103479574A (zh) * 2013-09-12 2014-01-01 华南农业大学 一种用于防治干奶期奶牛乳房炎的乳房注入剂及其制备方法
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CA3018204A1 (en) * 2016-03-22 2017-09-28 Advanced Animal Diagnostics, Inc. Methods and compositions for reducing antibiotic administration to farm animals
JP2019521083A (ja) * 2016-05-02 2019-07-25 レトロトップ、 インコーポレイテッドRetrotope, Inc. 同位体修飾された組成物およびその治療的使用
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BR112019002984A2 (pt) 2016-08-22 2019-05-14 Ambrx Inc fator de crescimento de fibroblasto 21 bovino e cetose em gado leiteiro
US11129906B1 (en) 2016-12-07 2021-09-28 David Gordon Bermudes Chimeric protein toxins for expression by therapeutic bacteria
MX2019008449A (es) 2017-02-08 2019-09-09 Bristol Myers Squibb Co Polipetidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos.
WO2019075053A1 (en) * 2017-10-11 2019-04-18 Elanco Us Inc. PORCINE G-CSF VARIANTS AND USES THEREOF
LT3773910T (lt) 2018-03-29 2024-09-25 Ambrx, Inc. Humanizuoto antikūno prieš prostatai specifinį membraninį antigeną (psma) konjugatai su vaistu
IL323061A (en) 2018-04-11 2025-10-01 Inhibrx Biosciences Inc Multispecific polypeptide constructs with forced CD3 binding and related methods and uses
CN119410679A (zh) 2018-05-01 2025-02-11 Ambrx公司 一种用于优化抗体表达的方法
US11562806B2 (en) * 2018-05-09 2023-01-24 Shenzhen Jingtai Technology Co., Ltd. Drug crystal structure landscape analysis system and landscape analysis method thereof
SG11202107201YA (en) * 2018-12-28 2021-07-29 Coherus Biosciences Inc Process for producing, isolating, and purifying modified recombinant proteins
CN110320296A (zh) * 2019-07-04 2019-10-11 公安部物证鉴定中心 一种3,4-亚甲二氧基乙卡西酮的检测方法
MX2023014212A (es) * 2021-06-02 2024-01-24 Elanco Us Inc Metodos para inhibir la mastitis bovina durante el periodo seco.
EP4503923A1 (en) 2022-04-04 2025-02-12 The Regents of the University of California Genetic complementation compositions and methods
EP4598586A1 (en) 2022-10-07 2025-08-13 Ambrx, Inc. Drug linkers and antibody conjugates thereof
KR20250134670A (ko) 2023-01-16 2025-09-11 암브룩스, 인코포레이티드 항-cd70 항체-약물 접합체
WO2024178310A1 (en) 2023-02-23 2024-08-29 Ambrx, Inc. Trop2-directed antibody-drug conjugates and uses thereof
WO2024241086A1 (en) 2023-05-24 2024-11-28 Ambrx, Inc. Pegylated bovine interferon lambda and methods of use thereof
WO2025041055A1 (en) 2023-08-22 2025-02-27 Ambrx, Inc. Anti-psma adc conjugate compositions and methods of use thereof

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