ATE405253T1 - Gelzusammensetzung mit geladenen polymeren - Google Patents

Gelzusammensetzung mit geladenen polymeren

Info

Publication number
ATE405253T1
ATE405253T1 AT05745554T AT05745554T ATE405253T1 AT E405253 T1 ATE405253 T1 AT E405253T1 AT 05745554 T AT05745554 T AT 05745554T AT 05745554 T AT05745554 T AT 05745554T AT E405253 T1 ATE405253 T1 AT E405253T1
Authority
AT
Austria
Prior art keywords
microparticles
gel composition
charged polymers
charged microparticles
gels
Prior art date
Application number
AT05745554T
Other languages
English (en)
Inventor
Tomme Sophie Van
Steenbergen Marinus Van
Nostrum Cornelis Van
Wilhelmus Hennink
Original Assignee
Univ Utrecht Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utrecht Holding Bv filed Critical Univ Utrecht Holding Bv
Application granted granted Critical
Publication of ATE405253T1 publication Critical patent/ATE405253T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1635—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/20—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Resins Obtained By Reactions Not Involving Carbon-To-Carbon Unsaturated Bonds (AREA)
AT05745554T 2004-05-13 2005-05-13 Gelzusammensetzung mit geladenen polymeren ATE405253T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP04076424A EP1595534A1 (de) 2004-05-13 2004-05-13 Gelzusammensetzung enthaltend geladenepolymere

Publications (1)

Publication Number Publication Date
ATE405253T1 true ATE405253T1 (de) 2008-09-15

Family

ID=34928217

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05745554T ATE405253T1 (de) 2004-05-13 2005-05-13 Gelzusammensetzung mit geladenen polymeren

Country Status (7)

Country Link
US (1) US20080226722A1 (de)
EP (3) EP1595534A1 (de)
JP (1) JP2007537249A (de)
AT (1) ATE405253T1 (de)
DE (1) DE602005009175D1 (de)
ES (1) ES2313346T3 (de)
WO (1) WO2005110377A1 (de)

Families Citing this family (35)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080131512A1 (en) * 1996-07-01 2008-06-05 Wilhelmus Everhardus Hennink Biodegradable hydrogels
DE102005050895A1 (de) * 2005-10-21 2007-04-26 Martin-Luther-Universität Halle-Wittenberg Polyelektrolytkomplexe zur Herstellung fester Arzneiformen und Verfahren zu ihrer Herstellung
US20080102123A1 (en) 2006-10-27 2008-05-01 Schachter Deborah M Self-gelling tunable drug delivery system
EP2025334A1 (de) * 2007-07-25 2009-02-18 OctoPlus Sciences B.V. Wirkstofffreisetzungssystem mit verzögerter Freisetzung für wiederholte Verabreichung
WO2010009510A1 (en) * 2008-07-24 2010-01-28 Anzon Australia Pty Limited A tool and method
WO2010074675A1 (en) * 2008-12-23 2010-07-01 Board Of Regents Of The University Of Texas System Inflammation targeting particles
EP2305717A1 (de) 2009-09-21 2011-04-06 Koninklijke Nederlandse Akademie van Wetenschappen Hemmung von TNIK zur Behandlung von Darmkrebs
US8975387B1 (en) * 2010-03-22 2015-03-10 North Carolina State University Modified carbohydrate-chitosan compounds, methods of making the same and methods of using the same
PT105058B (pt) * 2010-04-21 2013-04-17 Hovione Farmaciencia S A Processo para processamento de partículas de ingredientes activos farmacêuticos
EP2465928A1 (de) 2010-12-16 2012-06-20 Academisch Medisch Centrum bij de Universiteit van Amsterdam Behandlung von Th17-vermittelten Krankheiten
US8709466B2 (en) 2011-03-31 2014-04-29 International Business Machines Corporation Cationic polymers for antimicrobial applications and delivery of bioactive materials
US8642086B2 (en) 2011-03-31 2014-02-04 International Business Machines Corporation Antimicrobial compositions, methods of preparation thereof, and uses thereof
EP2700407A1 (de) * 2011-04-18 2014-02-26 Idemitsu Kosan Co., Ltd Granulate in flüssiger dosierungsform
CN102258808B (zh) * 2011-07-08 2013-08-14 西安交通大学 促视网膜色素上皮细胞扩增的水凝胶细胞支架的制备方法
HK1221415A1 (zh) * 2013-04-30 2017-06-02 Massachusetts Institute Of Technology 用於糖尿病治疗的可注射纳米网络凝胶
WO2015187631A1 (en) 2014-06-02 2015-12-10 Tethis, Inc. Modified biopolymers and methods of producing and using the same
WO2016049360A1 (en) * 2014-09-24 2016-03-31 Massachusetts Institute Of Technology Shear-thinning self-healing networks
EP3231433B1 (de) 2014-12-12 2023-12-27 Motejo. Ltd Mittel für subkutane injektion
JP5797864B1 (ja) * 2015-06-26 2015-10-21 ジーンメディカル株式会社 皮下注射用剤
JP5774190B1 (ja) * 2014-12-12 2015-09-09 ジーンメディカル株式会社 皮下注射用剤及び皮下注射用剤を含有する注射器の製造方法
CA3004346A1 (en) 2015-11-23 2017-06-01 Tethis, Inc. Coated particles and methods of making and using the same
US10590257B2 (en) 2016-09-26 2020-03-17 The Board Of Trustees Of The Leland Stanford Junior University Biomimetic, moldable, self-assembled cellulose silica-based trimeric hydrogels and their use as viscosity modifying carriers in industrial applications
EP3895742A1 (de) * 2016-10-13 2021-10-20 Allergan, Inc. Koazervat-hyaluronan-hydrogele für dermale füllstoffanwendungen
US11975123B2 (en) 2018-04-02 2024-05-07 The Board Of Trustees Of The Leland Stanford Junior University Adhesion prevention with shear-thinning polymeric hydrogels
US11969526B2 (en) 2017-04-03 2024-04-30 The Board Of Trustees Of The Leland Stanford Junior University Adhesion prevention with shear-thinning polymeric hydrogels
EP3581168A1 (de) * 2018-06-15 2019-12-18 Universiteit Utrecht Holding B.V. Zusammensetzung mit verzögerter freisetzung
WO2020072495A1 (en) 2018-10-01 2020-04-09 The Board Of Trustees Of The Leland Stanford Junior University Injectable hydrogels for controlled release of immunomodulatory compounds
CN111068111B (zh) * 2018-10-19 2022-03-22 胡尚秀 可注射型自组装微球凝胶、其用途及制备方法
TWI673103B (zh) 2018-10-19 2019-10-01 國立清華大學 可注射型自組裝微球凝膠、其用途及可注射型自組裝微球凝膠的製備方法
CN110713608A (zh) * 2019-09-17 2020-01-21 长春工业大学 一种核苷酸驱动的粘韧水凝胶的制备方法
CN111096924A (zh) * 2020-02-20 2020-05-05 山东大学 一种水包水防晒乳液及制备方法及应用
CN114652895A (zh) * 2020-12-23 2022-06-24 上海其胜生物制剂有限公司 一种可注射组织再生型壳聚糖复合凝胶支架的制备方法
JP2021072906A (ja) * 2021-01-18 2021-05-13 アラーガン、インコーポレイテッドＡｌｌｅｒｇａｎ，Ｉｎｃｏｒｐｏｒａｔｅｄ 皮膚充填剤用途のためのコアセルベートヒアルロナンヒドロゲル
CN118899557B (zh) * 2024-10-08 2025-04-18 河南师范大学 一种水凝胶电解质及其制备方法和应用
US12303604B1 (en) 2024-10-16 2025-05-20 Currax Pharmaceuticals Llc Pharmaceutical formulations comprising naltrexone and/or bupropion

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663286A (en) * 1984-02-13 1987-05-05 Damon Biotech, Inc. Encapsulation of materials
JPH01156341A (ja) * 1987-12-12 1989-06-19 Kanebo Ltd ポリイオンコンプレックスゲルの製造法
CA2121129A1 (en) * 1991-10-29 1993-05-13 Patrick Soon-Shiong Crosslinkable polysaccharides, polycations and lipids useful for encapsulation and drug release
AU7342296A (en) * 1995-10-25 1997-05-15 Octoplus Bv Cationic polyacrylates and poly(alkyl) acrylates or the corresponding acrylamides for use in synthetic transfection or blocking systems
WO1998000170A1 (en) * 1996-07-01 1998-01-08 Universiteit Utrecht Hydrolysable hydrogels for controlled release
US6060534A (en) * 1996-07-11 2000-05-09 Scimed Life Systems, Inc. Medical devices comprising ionically and non-ionically crosslinked polymer hydrogels having improved mechanical properties
US6395302B1 (en) 1996-11-19 2002-05-28 Octoplus B.V. Method for the preparation of microspheres which contain colloidal systems
AU5069798A (en) 1996-11-19 1998-06-10 Octoplus Bv Process for the preparation of a controlled release system
US6200595B1 (en) * 1998-04-24 2001-03-13 Kuraray Co., Ltd. Medical adhesive
JP3955160B2 (ja) * 1998-10-21 2007-08-08 独立行政法人科学技術振興機構 ポリイオンコンプレックスから成る分子応答性ゲル
US6713293B1 (en) * 1999-02-08 2004-03-30 Friedrich Grummt Encapsulated cells containing an amplified expression vector as a drug delivery device
ATE264669T1 (de) * 1999-02-19 2004-05-15 Univ Utrecht Stereokomplexe hydrogele
JP4149098B2 (ja) * 1999-09-13 2008-09-10 株式会社クラレ 水膨潤性医療用高分子ゲルの製造法及び水膨潤性医療用高分子ゲル
EP1184032A1 (de) 2000-08-31 2002-03-06 OctoPlus B.V. Dextranhydrogele
DE60132094T3 (de) 2001-10-26 2012-02-02 Octoplus Polyactive Sciences B.V. Verfahren zur Herstellung von gereinigten Partikeln
GB0130518D0 (en) * 2001-12-21 2002-02-06 Univ Gent Pulsed bio-agent delivery systems based on degradable polymer solutions or hydrogels
JP4321007B2 (ja) * 2002-04-25 2009-08-26 凸版印刷株式会社 多糖類複合体及びその製造方法
JP4583777B2 (ja) * 2003-06-30 2010-11-17 レンゴー株式会社 ポリイオンコンプレックス微粒子分散液及びポリイオンコンプレックス微粒子
JP4470410B2 (ja) * 2003-07-04 2010-06-02 凸版印刷株式会社 多糖類複合体

Also Published As

Publication number Publication date
EP1982700A1 (de) 2008-10-22
EP1595534A1 (de) 2005-11-16
WO2005110377A1 (en) 2005-11-24
DE602005009175D1 (de) 2008-10-02
EP1750679B1 (de) 2008-08-20
ES2313346T3 (es) 2009-03-01
US20080226722A1 (en) 2008-09-18
JP2007537249A (ja) 2007-12-20
EP1750679A1 (de) 2007-02-14

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