HK1221415A1 - 用於糖尿病治療的可注射納米網絡凝膠 - Google Patents

用於糖尿病治療的可注射納米網絡凝膠

Info

Publication number
HK1221415A1
HK1221415A1 HK16109650.4A HK16109650A HK1221415A1 HK 1221415 A1 HK1221415 A1 HK 1221415A1 HK 16109650 A HK16109650 A HK 16109650A HK 1221415 A1 HK1221415 A1 HK 1221415A1
Authority
HK
Hong Kong
Prior art keywords
diabetes treatment
network gels
injectable nano
injectable
nano
Prior art date
Application number
HK16109650.4A
Other languages
English (en)
Inventor
G Anderson Daniel
Gu Zhen
Arthur Aimetti Alex
S Langer Robert
Original Assignee
Massachusetts Inst Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology filed Critical Massachusetts Inst Technology
Publication of HK1221415A1 publication Critical patent/HK1221415A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/44—Oxidoreductases (1)
    • A61K38/443—Oxidoreductases (1) acting on CH-OH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/513—Organic macromolecular compounds; Dendrimers
    • A61K9/5161—Polysaccharides, e.g. alginate, chitosan, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y40/00—Manufacture or treatment of nanostructures

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nanotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
HK16109650.4A 2013-04-30 2016-08-12 用於糖尿病治療的可注射納米網絡凝膠 HK1221415A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361817752P 2013-04-30 2013-04-30
US201361864069P 2013-08-09 2013-08-09
PCT/US2014/035927 WO2014179344A1 (en) 2013-04-30 2014-04-29 Injectable nano-network gels for diabetes treatment

Publications (1)

Publication Number Publication Date
HK1221415A1 true HK1221415A1 (zh) 2017-06-02

Family

ID=51843897

Family Applications (2)

Application Number Title Priority Date Filing Date
HK16109650.4A HK1221415A1 (zh) 2013-04-30 2016-08-12 用於糖尿病治療的可注射納米網絡凝膠
HK16110684.2A HK1222546A1 (zh) 2013-04-30 2016-09-08 用於糖尿病治療的可注射納米網絡凝膠

Family Applications After (1)

Application Number Title Priority Date Filing Date
HK16110684.2A HK1222546A1 (zh) 2013-04-30 2016-09-08 用於糖尿病治療的可注射納米網絡凝膠

Country Status (11)

Country Link
US (1) US20160067190A1 (zh)
EP (1) EP2991673A4 (zh)
JP (1) JP2016517885A (zh)
KR (1) KR20160024853A (zh)
CN (1) CN105813652A (zh)
AU (1) AU2014260024B2 (zh)
BR (1) BR112015027561A8 (zh)
HK (2) HK1221415A1 (zh)
MX (1) MX2015015079A (zh)
RU (1) RU2015151135A (zh)
WO (1) WO2014179344A1 (zh)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2874562T3 (es) * 2014-12-19 2021-11-05 Kemin Ind Inc Suministro intraocular de moléculas bioactivas mediante el uso de iontoforesis
CN104740641B (zh) * 2015-04-08 2019-02-01 烟台大学 一种糖敏感的缓控释微球组合物及其制备方法
CN107530296B (zh) * 2015-04-21 2021-06-22 北卡罗来纳州立大学 使用缺氧敏感性纳米复合材料的葡萄糖响应性胰岛素递送系统
CA3026561C (en) * 2016-07-21 2021-10-26 Boston Scientific Scimed, Inc. Injectable compositions
US11351230B2 (en) 2016-11-07 2022-06-07 North Carolina State University Patch loaded with dual-sensitive vesicles for enhanced glucose-responsive insulin delivery
CA3045882A1 (en) 2016-12-05 2018-06-14 North Carolina State University Core-shell microneedle devices and uses thereof
CN106668840B (zh) * 2017-02-10 2020-02-14 南通大学 一种胰岛素控释药物及其制备方法与应用
WO2019055594A1 (en) * 2017-09-13 2019-03-21 North Carolina State University BRUSHING ADIPOSE TISSUE INDUCED LOCALLY BY MICRO-NEEDLE STAMPS FOR THE TREATMENT OF OBESITY
WO2019104006A1 (en) * 2017-11-21 2019-05-31 North Carolina State University Charge-switchable polymeric depot for glucose-triggered insulin delivery with ultrafast response
EP3735262A4 (en) * 2018-01-03 2021-09-29 Penn State Research Foundation GLUCOSE OXIDASE COMPOSITIONS USED AS AN ANTI-CONVULSIVER IN NEWBORNS
CN111195238A (zh) * 2018-10-31 2020-05-26 南方医科大学 一种用于胰岛素口服递送的聚电解质复合物
US20220204654A1 (en) * 2019-04-25 2022-06-30 Massachusetts Institute Of Technology Cyclodextrin supramolecular scaffolds and uses thereof
CN116474162A (zh) * 2023-04-28 2023-07-25 吉林大学 一种用于糖尿病慢性创伤修复的自修复水凝胶的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5359030A (en) * 1993-05-10 1994-10-25 Protein Delivery, Inc. Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
WO1998000170A1 (en) * 1996-07-01 1998-01-08 Universiteit Utrecht Hydrolysable hydrogels for controlled release
AU2003301064A1 (en) * 2002-12-17 2004-07-14 Massachusetts Institute Of Technology Stimuli-responsive systems for controlled drug delivery
WO2006088473A2 (en) * 2004-04-23 2006-08-24 Panduranga Rao Koritala Microcapsules and nanocapsules for the transmucosal delivery of therapeutic and diagnostic agents
EP1595534A1 (en) * 2004-05-13 2005-11-16 Universiteit Utrecht Holding B.V. Gel composition comprising charged polymers
TWI394580B (zh) * 2008-04-28 2013-05-01 Halozyme Inc 超快起作用胰島素組成物
US20110189299A1 (en) * 2008-07-01 2011-08-04 Nitto Denko Corporation Pharmaceutical composition containing surface-coated microparticles

Also Published As

Publication number Publication date
AU2014260024B2 (en) 2016-09-15
BR112015027561A8 (pt) 2019-12-24
US20160067190A1 (en) 2016-03-10
EP2991673A1 (en) 2016-03-09
RU2015151135A (ru) 2017-06-02
MX2015015079A (es) 2016-07-05
AU2014260024A1 (en) 2015-11-19
KR20160024853A (ko) 2016-03-07
WO2014179344A1 (en) 2014-11-06
BR112015027561A2 (pt) 2017-07-25
HK1222546A1 (zh) 2017-07-07
JP2016517885A (ja) 2016-06-20
CN105813652A (zh) 2016-07-27
EP2991673A4 (en) 2016-12-21

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