BRPI0916515B8 - polipeptídeo de fator estimulante de colônias de granulócitos bovino (bg-csf), formulação farmacêutica e composição compreendendo o mesmo - Google Patents

polipeptídeo de fator estimulante de colônias de granulócitos bovino (bg-csf), formulação farmacêutica e composição compreendendo o mesmo

Info

Publication number
BRPI0916515B8
BRPI0916515B8 BRPI0916515A BRPI0916515A BRPI0916515B8 BR PI0916515 B8 BRPI0916515 B8 BR PI0916515B8 BR PI0916515 A BRPI0916515 A BR PI0916515A BR PI0916515 A BRPI0916515 A BR PI0916515A BR PI0916515 B8 BRPI0916515 B8 BR PI0916515B8
Authority
BR
Brazil
Prior art keywords
csf
composition
same
pharmaceutical formulation
stimulating factor
Prior art date
Application number
BRPI0916515A
Other languages
English (en)
Inventor
Koder Alan
Maria A Hays Putnam Anna-
Ho Lillian
Knudsen Nick
C Canning Peter
Norman Thea
Kraynov Vadim
Original Assignee
Ambrx Inc
Elanco Us Inc
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ambrx Inc, Elanco Us Inc, Lilly Co Eli filed Critical Ambrx Inc
Publication of BRPI0916515A2 publication Critical patent/BRPI0916515A2/pt
Publication of BRPI0916515B1 publication Critical patent/BRPI0916515B1/pt
Publication of BRPI0916515B8 publication Critical patent/BRPI0916515B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Rheumatology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polyamides (AREA)

Abstract

polipeptídeos de g-csf bovinos modificados e usos dos mesmos. polipeptídeos de g-csf bovinos modificados e usos mesmos são fornecidos.
BRPI0916515A 2008-07-23 2009-07-22 polipeptídeo de fator estimulante de colônias de granulócitos bovino (bg-csf), formulação farmacêutica e composição compreendendo o mesmo BRPI0916515B8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8313208P 2008-07-23 2008-07-23
US61/083.132 2008-07-23
PCT/US2009/051388 WO2010011735A2 (en) 2008-07-23 2009-07-22 Modified bovine g-csf polypeptides and their uses

Publications (3)

Publication Number Publication Date
BRPI0916515A2 BRPI0916515A2 (pt) 2018-03-13
BRPI0916515B1 BRPI0916515B1 (pt) 2021-03-16
BRPI0916515B8 true BRPI0916515B8 (pt) 2021-07-27

Family

ID=41570844

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0916515A BRPI0916515B8 (pt) 2008-07-23 2009-07-22 polipeptídeo de fator estimulante de colônias de granulócitos bovino (bg-csf), formulação farmacêutica e composição compreendendo o mesmo

Country Status (23)

Country Link
US (3) US10138283B2 (pt)
EP (2) EP2318029B1 (pt)
JP (2) JP5680534B2 (pt)
KR (1) KR101726884B1 (pt)
CN (2) CN102159230A (pt)
AR (1) AR072967A1 (pt)
AU (1) AU2009274076C1 (pt)
BR (1) BRPI0916515B8 (pt)
CA (1) CA2729851C (pt)
CL (1) CL2011000013A1 (pt)
CO (1) CO6351745A2 (pt)
EA (1) EA019968B1 (pt)
ES (2) ES2654387T3 (pt)
IL (1) IL210265A (pt)
MX (1) MX2011000859A (pt)
NZ (2) NZ600382A (pt)
PA (1) PA8836801A1 (pt)
PE (1) PE20110426A1 (pt)
PL (2) PL2318029T3 (pt)
PT (1) PT2318029T (pt)
UA (2) UA118536C2 (pt)
WO (1) WO2010011735A2 (pt)
ZA (1) ZA201101166B (pt)

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AU2009296397B2 (en) 2008-09-26 2012-11-08 Ambrx Inc. Modified animal erythropoietin polypeptides and their uses
CN102260343A (zh) 2010-05-25 2011-11-30 健能隆医药技术（上海）有限公司 重组人g-csf二聚体在治疗神经损伤疾病中的用途
US9567386B2 (en) 2010-08-17 2017-02-14 Ambrx, Inc. Therapeutic uses of modified relaxin polypeptides
AU2011291943B2 (en) 2010-08-17 2015-01-22 Ambrx, Inc. Modified relaxin polypeptides and their uses
CN102380090A (zh) * 2010-08-31 2012-03-21 健能隆医药技术（上海）有限公司 G-csf二聚体在治疗嗜中性粒细胞减少症中的应用
AR083006A1 (es) * 2010-09-23 2013-01-23 Lilly Co Eli Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas
US9642917B2 (en) 2011-07-25 2017-05-09 Generon (Shanghai) Corporation, Ltd. Use of G-CSF dimer in preparation of medicament for treatment of neurodegenerative diseases
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WO2013130917A1 (en) * 2012-02-29 2013-09-06 Ambrx, Inc. Interleukin-3 polypeptide conjugates their uses
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AR113756A1 (es) * 2017-10-11 2020-06-10 Ambrx Inc Variantes porcinas de g-csf y sus usos
SG11202009670RA (en) 2018-03-29 2020-10-29 Ambrx Inc Humanized anti-prostate-specific membrane antigen (psma) antibody drug conjugates
SG11202010439VA (en) 2018-05-01 2020-11-27 Ambrx Inc A method for optimizing antibody expression
US11562806B2 (en) * 2018-05-09 2023-01-24 Shenzhen Jingtai Technology Co., Ltd. Drug crystal structure landscape analysis system and landscape analysis method thereof
EP3902820A2 (en) * 2018-12-28 2021-11-03 Coherus Biosciences, Inc. Process for producing, isolating, and purifying modified recombinant proteins
CN110320296A (zh) * 2019-07-04 2019-10-11 公安部物证鉴定中心 一种3,4-亚甲二氧基乙卡西酮的检测方法
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WO2024077277A1 (en) 2022-10-07 2024-04-11 Ambrx, Inc. Drug linkers and antibody conjugates thereof

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