ATE260674T1 - Stabilisierte proteinzusammensetzung - Google Patents

Stabilisierte proteinzusammensetzung

Info

Publication number
ATE260674T1
ATE260674T1 AT99306262T AT99306262T ATE260674T1 AT E260674 T1 ATE260674 T1 AT E260674T1 AT 99306262 T AT99306262 T AT 99306262T AT 99306262 T AT99306262 T AT 99306262T AT E260674 T1 ATE260674 T1 AT E260674T1
Authority
AT
Austria
Prior art keywords
protein composition
stabilized protein
stabilized
composition
protein
Prior art date
Application number
AT99306262T
Other languages
English (en)
Inventor
Peter Connor Canning
Barbara Jean Kamicker
Kasra Kasraian
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Application granted granted Critical
Publication of ATE260674T1 publication Critical patent/ATE260674T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Dermatology (AREA)
  • Endocrinology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT99306262T 1998-08-17 1999-08-06 Stabilisierte proteinzusammensetzung ATE260674T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US9687698P 1998-08-17 1998-08-17

Publications (1)

Publication Number Publication Date
ATE260674T1 true ATE260674T1 (de) 2004-03-15

Family

ID=22259521

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99306262T ATE260674T1 (de) 1998-08-17 1999-08-06 Stabilisierte proteinzusammensetzung

Country Status (17)

Country Link
US (1) US20050232898A1 (de)
EP (1) EP0988861B1 (de)
JP (1) JP3641170B2 (de)
CN (1) CN1250282C (de)
AR (1) AR016504A1 (de)
AT (1) ATE260674T1 (de)
AU (2) AU767431B2 (de)
BR (1) BR9904150A (de)
CA (1) CA2280449A1 (de)
DE (1) DE69915204T2 (de)
DK (1) DK0988861T3 (de)
ES (1) ES2216447T3 (de)
HK (1) HK1026151A1 (de)
NZ (2) NZ337258A (de)
PT (1) PT988861E (de)
TW (1) TWI221773B (de)
ZA (1) ZA995201B (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60103940T2 (de) * 2000-02-29 2005-07-28 Pfizer Products Inc., Groton Stabilisierter Granulozyten-Kolonie-stimulierender Faktor
EP1391209A4 (de) * 2001-05-30 2009-12-16 Chugai Pharmaceutical Co Ltd Proteinzubereitung
ITMI20021684A1 (it) * 2002-07-29 2004-01-29 Therapicon Srl Composizione farmaceutica di peptide nasale
ITBA20020032A1 (it) * 2002-09-24 2004-03-25 Bio D Soc Metodo per stabilizzare le proteine per la conservazione ad alte temperature.
MXPA05012099A (es) * 2003-05-09 2006-02-08 Schering Ag Tratamiento de enfermedades respiratorias inflamatorias.
US7585496B2 (en) 2003-11-04 2009-09-08 Lek Pharmaceuticals D.D. Stable pharmaceutical composition granulocyte-colony stimulating factor
EP1537876A1 (de) * 2003-12-01 2005-06-08 BioGeneriX AG Formulierung einer Erythropoietin Lösung
AU2004305535A1 (en) * 2003-12-09 2005-07-07 Alcon, Inc. Use of organic buffering agents to enhance the antimicrobial activity of pharmaceutical compositions
EP1817048B1 (de) * 2004-11-12 2014-02-12 Novo Nordisk A/S Stabile formulierungen insulinoptropischer peptide
EP1787658B1 (de) * 2005-11-10 2012-03-14 CHEMI S.p.A. Formulierungen mit verzögerter Freisetzung, die Somatostatin-analoge Wachstumshormoninhibitoren enthalten
DE202006020194U1 (de) 2006-03-01 2007-12-06 Bioceuticals Arzneimittel Ag G-CSF-Flüssigformulierung
EP2094247B1 (de) 2006-10-20 2022-06-29 Amgen Inc. Stabile polypeptid-formulierungen
AU2008291309B2 (en) 2007-08-27 2013-10-17 Ratiopharm Gmbh Liquid formulation of G-CSF
AU2008311244C1 (en) * 2007-10-09 2013-11-07 Solenis Technologies Cayman, L.P. Crosslinker-containing adhesive compositions
UA103774C2 (uk) * 2008-07-23 2013-11-25 Амбркс, Інк. Модифіковані поліпептиди бичачого гранулоцитарного колонієстимулювального фактора (g-csf) та їх застосування
TWI480288B (zh) * 2010-09-23 2015-04-11 Lilly Co Eli 牛顆粒細胞群落刺激因子及其變體之調配物
ITMI20120338A1 (it) * 2012-03-06 2013-09-07 Dr Andrea Bignotti Preparato terapeutico e procedimento di preparazione di detto preparato terapeutico
GB2516808A (en) * 2013-05-31 2015-02-11 Innova Biosciences Ltd Antibody composition and buffer system therefor
US11464831B2 (en) 2015-01-05 2022-10-11 Cornell University Compositions and methods using IL-8 for improving health of mammals
EP3242675B1 (de) 2015-01-05 2022-11-30 Cornell University Zusammensetzungen und verfahren mit il-8 zur verbesserung der milchproduktion und fortpflanzungsgesundheit bei säugetieren
ES2952744T3 (es) 2016-12-15 2023-11-03 Nestle Sa Composiciones y procedimientos que modulan los glóbulos blancos o los neutrófilos en un animal de compañía
EP3771463A1 (de) 2019-07-29 2021-02-03 Ludwig-Maximilians-Universität München Stabilisierung therapeutischer proteine mit piperazin- oder morpholinhaltigen zwitterionischen puffersubstanzen
CN116836920B (zh) * 2023-08-21 2024-05-24 广东横琴粤澳深度合作区齐美国际干细胞医院有限公司 一种无血清培养基及其制备间充质干细胞的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3273597D1 (en) * 1981-11-28 1986-11-06 Sunstar Kk Pharmaceutical composition containing interferon in stable state
JPS6069037A (ja) * 1983-09-26 1985-04-19 Sunstar Inc エリテマト−デス治療用外用剤
US4605555A (en) * 1984-09-20 1986-08-12 Sun Star Kabushiki Kaisha Composition and method for treating keratosic disorder of skin and mucosa
JPH0618781B2 (ja) * 1986-10-18 1994-03-16 中外製薬株式会社 感染症治療剤
EP0347041A3 (de) * 1988-05-13 1990-11-22 Amgen Inc. Zusammensetzungen und Verfahren zur Behandlung oder Verhütung von Infektionen bei Tieren
US5013714A (en) * 1988-12-15 1991-05-07 Lindstrom Richard L Viscoelastic solution
US6066469A (en) * 1990-03-08 2000-05-23 Ferro Dynamics, Inc. Cloning, expression, and uses of human lactoferrin
DE4242919A1 (de) * 1992-12-18 1994-06-23 Boehringer Mannheim Gmbh Verfahren zur Herstellung von lagerstabilen wässrigen pharmazeutischen Zubereitungen von G-CSF
US5580856A (en) * 1994-07-15 1996-12-03 Prestrelski; Steven J. Formulation of a reconstituted protein, and method and kit for the production thereof

Also Published As

Publication number Publication date
DE69915204T2 (de) 2004-07-29
AR016504A1 (es) 2001-07-04
CN1250282C (zh) 2006-04-12
EP0988861B1 (de) 2004-03-03
BR9904150A (pt) 2000-12-26
TWI221773B (en) 2004-10-11
PT988861E (pt) 2004-06-30
DE69915204D1 (de) 2004-04-08
EP0988861A1 (de) 2000-03-29
NZ510140A (en) 2005-01-28
HK1026151A1 (en) 2000-12-08
AU767431B2 (en) 2003-11-13
AU2004200568A1 (en) 2004-03-11
JP2000063264A (ja) 2000-02-29
US20050232898A1 (en) 2005-10-20
ZA995201B (en) 2001-02-16
DK0988861T3 (da) 2004-04-19
CA2280449A1 (en) 2000-02-17
NZ337258A (en) 2001-04-27
AU4450199A (en) 2000-03-09
CN1250668A (zh) 2000-04-19
JP3641170B2 (ja) 2005-04-20
ES2216447T3 (es) 2004-10-16

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