JP2015532307A5 - - Google Patents

Download PDF

Info

Publication number
JP2015532307A5
JP2015532307A5 JP2015536187A JP2015536187A JP2015532307A5 JP 2015532307 A5 JP2015532307 A5 JP 2015532307A5 JP 2015536187 A JP2015536187 A JP 2015536187A JP 2015536187 A JP2015536187 A JP 2015536187A JP 2015532307 A5 JP2015532307 A5 JP 2015532307A5
Authority
JP
Japan
Prior art keywords
factor vii
polypeptide
polypeptide according
polymer
asn
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2015536187A
Other languages
English (en)
Japanese (ja)
Other versions
JP2015532307A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/EP2013/071510 external-priority patent/WO2014060401A1/en
Publication of JP2015532307A publication Critical patent/JP2015532307A/ja
Publication of JP2015532307A5 publication Critical patent/JP2015532307A5/ja
Withdrawn legal-status Critical Current

Links

JP2015536187A 2012-10-15 2013-10-15 凝固因子viiポリペプチド Withdrawn JP2015532307A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP12188473 2012-10-15
EP12188473.8 2012-10-15
US201261715920P 2012-10-19 2012-10-19
US61/715,920 2012-10-19
PCT/EP2013/071510 WO2014060401A1 (en) 2012-10-15 2013-10-15 Coagulation factor vii polypeptides

Publications (2)

Publication Number Publication Date
JP2015532307A JP2015532307A (ja) 2015-11-09
JP2015532307A5 true JP2015532307A5 (enExample) 2016-12-01

Family

ID=47022566

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015536187A Withdrawn JP2015532307A (ja) 2012-10-15 2013-10-15 凝固因子viiポリペプチド

Country Status (5)

Country Link
US (1) US20150307865A1 (enExample)
EP (1) EP2906693A1 (enExample)
JP (1) JP2015532307A (enExample)
CN (1) CN104704118A (enExample)
WO (1) WO2014060401A1 (enExample)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI465247B (zh) 2008-04-11 2014-12-21 Catalyst Biosciences Inc 經修飾的因子vii多肽和其用途
WO2011075185A1 (en) 2009-12-18 2011-06-23 Oligasis Targeted drug phosphorylcholine polymer conjugates
US20150259665A1 (en) 2012-10-15 2015-09-17 Novo Nordisk Health Care Ag Factor vii conjugates
WO2015035342A2 (en) 2013-09-08 2015-03-12 Oligasis Llc Factor viii zwitterionic polymer conjugates
KR20160065925A (ko) * 2013-10-15 2016-06-09 노보 노르디스크 헬스 케어 악티엔게젤샤프트 응고 인자 vii 폴리펩티드
US9840553B2 (en) 2014-06-28 2017-12-12 Kodiak Sciences Inc. Dual PDGF/VEGF antagonists
JP6849590B2 (ja) 2014-10-17 2021-03-24 コディアック サイエンシーズ インコーポレイテッドKodiak Sciences Inc. ブチリルコリンエステラーゼ両性イオン性ポリマーコンジュゲート
BR112018013407A2 (en) 2015-12-30 2018-12-18 Kodiak Sciences Inc. antibodies and conjugates thereof
BR112019000610A2 (pt) 2016-07-11 2019-07-02 Opko Biologics Ltd fator vii de coagulação de longa ação e métodos de produção do mesmo
CN106279436B (zh) * 2016-08-19 2017-10-31 安源医药科技(上海)有限公司 活化的人凝血因子vii融合蛋白及其制备方法与用途
CN107102125B (zh) * 2017-04-17 2019-07-09 中国科学院苏州生物医学工程技术研究所 血栓弹力图仪的校准方法
SG11202008242XA (en) 2018-03-02 2020-09-29 Kodiak Sciences Inc Il-6 antibodies and fusion constructs and conjugates thereof
CN110218258A (zh) * 2019-06-12 2019-09-10 福建农林大学 融合三肽囊素的克隆表达及应用
US20210069306A1 (en) * 2019-08-15 2021-03-11 Catalyst Biosciences, Inc. Modified factor vii polypeptides for subcutaneous administration and on-demand treatment
US11912784B2 (en) 2019-10-10 2024-02-27 Kodiak Sciences Inc. Methods of treating an eye disorder

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4203570A (en) 1978-08-23 1980-05-20 The Western States Machine Company Power-operated loading gate for centrifugal machines incorporating an auxiliary drive device
US4873191A (en) 1981-06-12 1989-10-10 Ohio University Genetic transformation of zygotes
US4456591A (en) 1981-06-25 1984-06-26 Baxter Travenol Laboratories, Inc. Therapeutic method for activating factor VII
US4546082A (en) 1982-06-17 1985-10-08 Regents Of The Univ. Of California E. coli/Saccharomyces cerevisiae plasmid cloning vector containing the alpha-factor gene for secretion and processing of hybrid proteins
US4599311A (en) 1982-08-13 1986-07-08 Kawasaki Glenn H Glycolytic promotersfor regulated protein expression: protease inhibitor
US4713339A (en) 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
WO1984004330A1 (en) 1983-04-22 1984-11-08 Amgen Secretion of exogenous polypeptides from yeast
NZ207926A (en) 1983-04-25 1988-04-29 Genentech Inc Use of yeast #a#-factor to assist in expression of proteins heterologus to yeast
US4745051A (en) 1983-05-27 1988-05-17 The Texas A&M University System Method for producing a recombinant baculovirus expression vector
US4870008A (en) 1983-08-12 1989-09-26 Chiron Corporation Secretory expression in eukaryotes
US4879236A (en) 1984-05-16 1989-11-07 The Texas A&M University System Method for producing a recombinant baculovirus expression vector
US4931373A (en) 1984-05-25 1990-06-05 Zymogenetics, Inc. Stable DNA constructs for expression of α-1 antitrypsin
DK58285D0 (da) 1984-05-30 1985-02-08 Novo Industri As Peptider samt fremstilling og anvendelse deraf
US4766073A (en) 1985-02-25 1988-08-23 Zymogenetics Inc. Expression of biologically active PDGF analogs in eucaryotic cells
US4885249A (en) 1984-12-05 1989-12-05 Allelix, Inc. Aspergillus niger transformation system
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
GR860984B (en) 1985-04-17 1986-08-18 Zymogenetics Inc Expression of factor vii and ix activities in mammalian cells
DE3650202T3 (de) 1985-08-29 2004-06-03 Genencor International, Inc., South San Francisco Expression von heterologen Polypeptiden in filamentösen Pilzen, Verfahren zu deren Herstellung und Vektoren zu deren Herstellung.
UA41863C2 (uk) 1985-10-25 2001-10-15 Займодженетікс Інк. Спосіб одержання гетерологічного поліпептиду в еукаріотичних мікроорганізмах
US4882279A (en) 1985-10-25 1989-11-21 Phillips Petroleum Company Site selective genomic modification of yeast of the genus pichia
US4935349A (en) 1986-01-17 1990-06-19 Zymogenetics, Inc. Expression of higher eucaryotic genes in aspergillus
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
GB8610600D0 (en) 1986-04-30 1986-06-04 Novo Industri As Transformation of trichoderma
GB8615942D0 (en) 1986-06-30 1986-08-06 Animal & Food Research Council Peptide production
NZ221259A (en) 1986-07-31 1990-05-28 Calgene Inc Seed specific transcriptional regulation
EP0832981A1 (en) 1987-02-17 1998-04-01 Pharming B.V. DNA sequences to target proteins to the mammary gland for efficient secretion
US4873316A (en) 1987-06-23 1989-10-10 Biogen, Inc. Isolation of exogenous recombinant proteins from the milk of transgenic mammals
DE3856247T2 (de) 1987-07-24 1999-04-29 Chiron Corp., Emeryville, Calif. Züchtung von insektenzellen mit airlift-reaktoren
US5024947A (en) 1987-07-24 1991-06-18 Cetus Corporation Serum free media for the growth on insect cells and expression of products thereby
US5004697A (en) 1987-08-17 1991-04-02 Univ. Of Ca Cationized antibodies for delivery through the blood-brain barrier
WO1989001969A1 (en) 1987-09-04 1989-03-09 Novo-Nordisk A/S Process for the production of protein products in aspergillus and promoters for use in aspergillus
DK463887D0 (da) 1987-09-07 1987-09-07 Novo Industri As Gaerleader
US5037743A (en) 1988-08-05 1991-08-06 Zymogenetics, Inc. BAR1 secretion signal
GB8826446D0 (en) 1988-11-11 1988-12-14 Agricultural & Food Res Peptide production
WO1990005783A1 (en) 1988-11-18 1990-05-31 Cetus Corporation Insect signal peptide mediated secretion of recombinant proteins
GB8910962D0 (en) 1989-05-12 1989-06-28 Natural Environment Res Novel baculovirus expression vectors and use thereof in the expression of foreign proteins in insects or insect cells
US5162222A (en) 1989-07-07 1992-11-10 Guarino Linda A Use of baculovirus early promoters for expression of foreign genes in stably transformed insect cells or recombinant baculoviruses
US5077214A (en) 1989-07-07 1991-12-31 The Texas A&M University System Use of baculovirus early promoters for expression of foreign genes in stably transformed insect cells
US5023328A (en) 1989-08-04 1991-06-11 The Texas A&M University System Lepidopteran AKH signal sequence
US5073964A (en) 1989-08-04 1991-12-17 Aware, Inc. Signal processing device and method
US5155037A (en) 1989-08-04 1992-10-13 The Texas A&M University System Insect signal sequences useful to improve the efficiency of processing and secretion of foreign genes in insect systems
DK300090D0 (da) 1990-12-19 1990-12-19 Novo Nordisk As Fremgangsmaade til fremstilling af leadersekvenser
AU1228592A (en) 1991-01-11 1992-08-17 American Red Cross Expression of active human protein c in mammary tissue of transgenic animals
PL204285B1 (pl) * 2000-02-11 2009-12-31 Bayer Healthcare Llc Koniugat polipeptydowy, polipeptyd, sekwencja nukleotydowa, wektor ekspresyjny, komórka gospodarz, sposób wytwarzania koniugatu polipeptydowego, środek farmaceutyczny i zastosowanie koniugatu polipeptydowego
CZ2003611A3 (cs) * 2000-09-13 2003-08-13 Novo Nordisk A/S Varianty lidského koagulačního faktoru VII
CZ20032454A3 (en) 2001-03-22 2004-03-17 Novo Nordisk Health Care Ag Coagulation factor vii derivative
EP2305312B1 (en) 2001-10-10 2015-03-04 ratiopharm GmbH Remodelling and glycoconjugation of follicle-stimulating hormone (FSH)
WO2006134174A2 (en) * 2005-06-17 2006-12-21 Novo Nordisk Health Care Ag Dimeric and multimeric fviia compound
JP5690047B2 (ja) 2005-09-14 2015-03-25 ノボ ノルディスク ヘルス ケア アーゲー ヒト凝固第vii因子ポリペプチド
ATE485052T1 (de) 2006-04-07 2010-11-15 Novo Nordisk Healthcare Ag Kovalenter faktor vii-gewebefaktor-komplex
US9687559B2 (en) 2008-03-19 2017-06-27 The Board Of Regents Of The University Of Oklahoma Heparosan polymers and methods of making and using same for the enhancement of therapeutics
TWI465247B (zh) 2008-04-11 2014-12-21 Catalyst Biosciences Inc 經修飾的因子vii多肽和其用途
CA2773755C (en) * 2008-09-09 2017-04-25 The Board Of Regents Of The University Of Oklahoma Heparosan polymers and methods of making and using same for the enhancement of therapeutics

Similar Documents

Publication Publication Date Title
JP2015532307A5 (enExample)
US12303550B2 (en) Neuroprotective peptides
JP2015502991A5 (enExample)
EA202192588A1 (ru) Фармацевтическая композиция, включающая вариант ph20 гиалуронидазы человека, и лекарственное средство для подкожного введения
HRP20140616T1 (hr) Peptidni analog oksintomodulina
TW201613958A (en) MIC-1 fusion proteins and uses thereof
JP2018522563A5 (enExample)
JP2014526441A5 (enExample)
JP2011523935A5 (enExample)
BR112019002394A2 (pt) citocina fundida com fc heterodimérico e composição farmacêutica compreendendo o mesmo
JP2013533273A5 (enExample)
AR064555A1 (es) Peptido wt1 restringido a hla-a*1101 y composicion farmaceutica que comprende el mismo
RU2008141280A (ru) Агонисты рецептора нейромедина u и их применение
CN101588820A (zh) α-乳清蛋白组合物
RU2013139651A (ru) Новые соединения, влияющие на пищевое поведение
JP2019533722A5 (enExample)
CN103097405B (zh) 用于伤口愈合的新型肽
JP2015512927A5 (enExample)
JP2016536357A5 (enExample)
MY190257A (en) Optimised subcutaneous therapeutic agents
JP2009533355A5 (enExample)
JP2013531651A5 (enExample)
JP2016520620A5 (enExample)
RU2011133224A (ru) Новые фармацевтические композиции
AR061825A1 (es) Analogos del peptido intestinal vasoactivo (vip)