MX2011000859A - Polipeptidos g-csf bovinos modificados y sus usos. - Google Patents
Polipeptidos g-csf bovinos modificados y sus usos.Info
- Publication number
- MX2011000859A MX2011000859A MX2011000859A MX2011000859A MX2011000859A MX 2011000859 A MX2011000859 A MX 2011000859A MX 2011000859 A MX2011000859 A MX 2011000859A MX 2011000859 A MX2011000859 A MX 2011000859A MX 2011000859 A MX2011000859 A MX 2011000859A
- Authority
- MX
- Mexico
- Prior art keywords
- csf
- amino acid
- polypeptide
- group
- csf polypeptide
- Prior art date
Links
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/53—Colony-stimulating factor [CSF]
- C07K14/535—Granulocyte CSF; Granulocyte-macrophage CSF
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P15/14—Drugs for genital or sexual disorders; Contraceptives for lactation disorders, e.g. galactorrhoea
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- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
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- A—HUMAN NECESSITIES
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- A—HUMAN NECESSITIES
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- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| CN102260343A (zh) | 2010-05-25 | 2011-11-30 | 健能隆医药技术（上海）有限公司 | 重组人g-csf二聚体在治疗神经损伤疾病中的用途 |
| KR101963460B1 (ko) | 2010-08-17 | 2019-03-28 | 암브룩스, 인코포레이티드 | 변형된 릴랙신 폴리펩타이드 및 그것의 용도 |
| US9567386B2 (en) | 2010-08-17 | 2017-02-14 | Ambrx, Inc. | Therapeutic uses of modified relaxin polypeptides |
| CN102380090A (zh) * | 2010-08-31 | 2012-03-21 | 健能隆医药技术（上海）有限公司 | G-csf二聚体在治疗嗜中性粒细胞减少症中的应用 |
| AR083006A1 (es) | 2010-09-23 | 2013-01-23 | Lilly Co Eli | Formulaciones para el factor estimulante de colonias de granulocitos (g-csf) bovino y variantes de las mismas |
| US9642917B2 (en) | 2011-07-25 | 2017-05-09 | Generon (Shanghai) Corporation, Ltd. | Use of G-CSF dimer in preparation of medicament for treatment of neurodegenerative diseases |
| WO2013022328A1 (en) * | 2011-08-09 | 2013-02-14 | Uab Profarma | Derivatives of recombinant proteins, homo-multimers of granulocyte colony-stimulating factor and method of preparation thereof |
| WO2013130917A1 (en) * | 2012-02-29 | 2013-09-06 | Ambrx, Inc. | Interleukin-3 polypeptide conjugates their uses |
| CN103479574A (zh) * | 2013-09-12 | 2014-01-01 | 华南农业大学 | 一种用于防治干奶期奶牛乳房炎的乳房注入剂及其制备方法 |
| EP3283508B1 (en) | 2015-04-17 | 2021-03-17 | Alpine Immune Sciences, Inc. | Immunomodulatory proteins with tunable affinities |
| CA3018204A1 (en) * | 2016-03-22 | 2017-09-28 | Advanced Animal Diagnostics, Inc. | Methods and compositions for reducing antibiotic administration to farm animals |
| JP2019521083A (ja) * | 2016-05-02 | 2019-07-25 | レトロトップ、 インコーポレイテッドＲｅｔｒｏｔｏｐｅ， Ｉｎｃ． | 同位体修飾された組成物およびその治療的使用 |
| WO2017222940A1 (en) | 2016-06-20 | 2017-12-28 | Eli Lilly And Company | Pegylated porcine interferon and methods of use thereof |
| BR112019002984A2 (pt) | 2016-08-22 | 2019-05-14 | Ambrx Inc | fator de crescimento de fibroblasto 21 bovino e cetose em gado leiteiro |
| US11129906B1 (en) | 2016-12-07 | 2021-09-28 | David Gordon Bermudes | Chimeric protein toxins for expression by therapeutic bacteria |
| MX2019008449A (es) | 2017-02-08 | 2019-09-09 | Bristol Myers Squibb Co | Polipetidos de relaxina modificada que comprenden un mejorador farmacocinetico y sus usos. |
| WO2019075053A1 (en) * | 2017-10-11 | 2019-04-18 | Elanco Us Inc. | PORCINE G-CSF VARIANTS AND USES THEREOF |
| LT3773910T (lt) | 2018-03-29 | 2024-09-25 | Ambrx, Inc. | Humanizuoto antikūno prieš prostatai specifinį membraninį antigeną (psma) konjugatai su vaistu |
| IL323061A (en) | 2018-04-11 | 2025-10-01 | Inhibrx Biosciences Inc | Multispecific polypeptide constructs with forced CD3 binding and related methods and uses |
| CN119410679A (zh) | 2018-05-01 | 2025-02-11 | Ambrx公司 | 一种用于优化抗体表达的方法 |
| US11562806B2 (en) * | 2018-05-09 | 2023-01-24 | Shenzhen Jingtai Technology Co., Ltd. | Drug crystal structure landscape analysis system and landscape analysis method thereof |
| SG11202107201YA (en) * | 2018-12-28 | 2021-07-29 | Coherus Biosciences Inc | Process for producing, isolating, and purifying modified recombinant proteins |
| CN110320296A (zh) * | 2019-07-04 | 2019-10-11 | 公安部物证鉴定中心 | 一种3,4-亚甲二氧基乙卡西酮的检测方法 |
| MX2023014212A (es) * | 2021-06-02 | 2024-01-24 | Elanco Us Inc | Metodos para inhibir la mastitis bovina durante el periodo seco. |
| EP4503923A1 (en) | 2022-04-04 | 2025-02-12 | The Regents of the University of California | Genetic complementation compositions and methods |
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| KR20250134670A (ko) | 2023-01-16 | 2025-09-11 | 암브룩스, 인코포레이티드 | 항-cd70 항체-약물 접합체 |
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| WO2025041055A1 (en) | 2023-08-22 | 2025-02-27 | Ambrx, Inc. | Anti-psma adc conjugate compositions and methods of use thereof |
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