NO324264B1 - Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmate samt medikament for medisinsk bruk. - Google Patents

Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmate samt medikament for medisinsk bruk. Download PDF

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Publication number
NO324264B1
NO324264B1 NO19994869A NO994869A NO324264B1 NO 324264 B1 NO324264 B1 NO 324264B1 NO 19994869 A NO19994869 A NO 19994869A NO 994869 A NO994869 A NO 994869A NO 324264 B1 NO324264 B1 NO 324264B1
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NO
Norway
Prior art keywords
antibody
vegf
seq
human
antibody according
Prior art date
Application number
NO19994869A
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English (en)
Norwegian (no)
Other versions
NO994869D0 (no
NO994869L (no
Inventor
Leonard G Presta
Manuel Baca
James A Wells
Henry B Lowman
Yvonne Man-Yee Chen
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27125626&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO324264(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US08/908,469 external-priority patent/US6884879B1/en
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of NO994869D0 publication Critical patent/NO994869D0/no
Publication of NO994869L publication Critical patent/NO994869L/no
Publication of NO324264B1 publication Critical patent/NO324264B1/no

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/22Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/005Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/55Fab or Fab'
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/569Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/90Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Air Bags (AREA)
  • Steering Control In Accordance With Driving Conditions (AREA)
NO19994869A 1997-04-07 1999-10-06 Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmate samt medikament for medisinsk bruk. NO324264B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83350497A 1997-04-07 1997-04-07
US08/908,469 US6884879B1 (en) 1997-04-07 1997-08-06 Anti-VEGF antibodies
PCT/US1998/006604 WO1998045331A2 (en) 1997-04-07 1998-04-03 Anti-vegf antibodies

Publications (3)

Publication Number Publication Date
NO994869D0 NO994869D0 (no) 1999-10-06
NO994869L NO994869L (no) 1999-12-06
NO324264B1 true NO324264B1 (no) 2007-09-17

Family

ID=27125626

Family Applications (3)

Application Number Title Priority Date Filing Date
NO19994869A NO324264B1 (no) 1997-04-07 1999-10-06 Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmate samt medikament for medisinsk bruk.
NO2007015C NO2007015I1 (no) 1997-04-07 2007-12-20 Ranibizumab
NO2007014C NO2007014I2 (no) 1997-04-07 2007-12-20 Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmåte samt medikament for medisinsk bruk

Family Applications After (2)

Application Number Title Priority Date Filing Date
NO2007015C NO2007015I1 (no) 1997-04-07 2007-12-20 Ranibizumab
NO2007014C NO2007014I2 (no) 1997-04-07 2007-12-20 Anti-VEGF-antistoff, sammensetning, nukleinsyre, vektor, vertcelle, fremgangsmåte samt medikament for medisinsk bruk

Country Status (26)

Country Link
US (2) US7060269B1 (zh)
EP (4) EP1787999B1 (zh)
JP (1) JP3957765B2 (zh)
KR (2) KR100870353B1 (zh)
CN (1) CN100480269C (zh)
AT (2) ATE349470T1 (zh)
AU (1) AU743758B2 (zh)
BR (1) BRPI9809387B8 (zh)
CA (1) CA2286330C (zh)
CY (3) CY2005008I2 (zh)
DE (5) DE69829891T2 (zh)
DK (2) DK1325932T5 (zh)
ES (2) ES2236634T3 (zh)
FR (2) FR05C0020I2 (zh)
GE (1) GEP20105118B (zh)
HK (2) HK1023577A1 (zh)
IL (1) IL132240A0 (zh)
LT (1) LTPA2005005I1 (zh)
LU (2) LU91167I2 (zh)
NL (2) NL300193I2 (zh)
NO (3) NO324264B1 (zh)
NZ (1) NZ500078A (zh)
PT (1) PT1325932E (zh)
SI (1) SI1325932T1 (zh)
TR (1) TR199903123T2 (zh)
WO (1) WO1998045331A2 (zh)

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