NO20030270L - Prodroger av fosfonatnukleotidanaloger, og fremgangsmåter for utvelgelse ogfremstilling av disse - Google Patents

Prodroger av fosfonatnukleotidanaloger, og fremgangsmåter for utvelgelse ogfremstilling av disse

Info

Publication number
NO20030270L
NO20030270L NO20030270A NO20030270A NO20030270L NO 20030270 L NO20030270 L NO 20030270L NO 20030270 A NO20030270 A NO 20030270A NO 20030270 A NO20030270 A NO 20030270A NO 20030270 L NO20030270 L NO 20030270L
Authority
NO
Norway
Prior art keywords
prodrugs
preparing
selecting
methods
nucleotide analogs
Prior art date
Application number
NO20030270A
Other languages
English (en)
Other versions
NO336718B1 (no
NO20030270D0 (no
Inventor
Mark W Becker
Harlan H Chapman
Tomas Cihlar
Eugene J Eisenberg
Gong-Xin He
Michael R Kernan
William A Lee
Ernest J Prisbe
John C Rohloff
Mark L Sparacino
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22821718&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NO20030270(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of NO20030270D0 publication Critical patent/NO20030270D0/no
Publication of NO20030270L publication Critical patent/NO20030270L/no
Publication of NO336718B1 publication Critical patent/NO336718B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
NO20030270A 2000-07-21 2003-01-20 Prodroger av fosfonatnukleotidanaloger, preparat derav og dets anvendelse til terapeutisk og profylaktisk behandling av virusinfeksjoner NO336718B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22002100P 2000-07-21 2000-07-21
PCT/US2001/023104 WO2002008241A2 (en) 2000-07-21 2001-07-20 Prodrugs of phosphonate nucleotide analogues and methods for selecting and making same

Publications (3)

Publication Number Publication Date
NO20030270D0 NO20030270D0 (no) 2003-01-20
NO20030270L true NO20030270L (no) 2003-03-20
NO336718B1 NO336718B1 (no) 2015-10-26

Family

ID=22821718

Family Applications (6)

Application Number Title Priority Date Filing Date
NO20030270A NO336718B1 (no) 2000-07-21 2003-01-20 Prodroger av fosfonatnukleotidanaloger, preparat derav og dets anvendelse til terapeutisk og profylaktisk behandling av virusinfeksjoner
NO20120466A NO20120466L (no) 2000-07-21 2012-04-23 Prodroger av fosfonatnukleotidanaloger, og fremgangsmater for utvelgelse og fremstilling av disse
NO20131717A NO20131717L (no) 2000-07-21 2013-12-20 Prodroger av fosfonatnukleotidanaloger, og fremgangsmåter for utvelgelse og fremstilling av disse
NO20150909A NO20150909L (no) 2000-07-21 2015-07-10 Prodroger av fosfonatnukleotidanaloger, og fremgangsmåter for utvelgelse og fremstilling av disse
NO2016006C NO2016006I1 (no) 2000-07-21 2016-04-19 Prodroger av fosfonatnukleotidanaloger,preparat derav og dets anvendelse til terapeutisk og profylaktisk behandling av virusinfeksjoner
NO2023006C NO2023006I1 (no) 2000-07-21 2023-02-03 Tenofovir alafenamide or a salt or solvate thereof, especially tenofovir alafenamide fumarate - forlengelse

Family Applications After (5)

Application Number Title Priority Date Filing Date
NO20120466A NO20120466L (no) 2000-07-21 2012-04-23 Prodroger av fosfonatnukleotidanaloger, og fremgangsmater for utvelgelse og fremstilling av disse
NO20131717A NO20131717L (no) 2000-07-21 2013-12-20 Prodroger av fosfonatnukleotidanaloger, og fremgangsmåter for utvelgelse og fremstilling av disse
NO20150909A NO20150909L (no) 2000-07-21 2015-07-10 Prodroger av fosfonatnukleotidanaloger, og fremgangsmåter for utvelgelse og fremstilling av disse
NO2016006C NO2016006I1 (no) 2000-07-21 2016-04-19 Prodroger av fosfonatnukleotidanaloger,preparat derav og dets anvendelse til terapeutisk og profylaktisk behandling av virusinfeksjoner
NO2023006C NO2023006I1 (no) 2000-07-21 2023-02-03 Tenofovir alafenamide or a salt or solvate thereof, especially tenofovir alafenamide fumarate - forlengelse

Country Status (37)

Country Link
US (10) US20040018150A1 (no)
EP (3) EP2682397B1 (no)
JP (4) JP4651264B2 (no)
KR (2) KR100767432B1 (no)
CN (2) CN1291994C (no)
AP (1) AP1466A (no)
AU (3) AU2001282941C1 (no)
BE (1) BE2016C018I2 (no)
BG (1) BG66037B1 (no)
BR (1) BRPI0112646B8 (no)
CA (3) CA2893174A1 (no)
CY (2) CY2016008I2 (no)
CZ (2) CZ304734B6 (no)
DK (2) DK1301519T4 (no)
EA (1) EA004926B1 (no)
EE (1) EE05366B1 (no)
ES (2) ES2627903T3 (no)
FR (1) FR16C0013I2 (no)
HK (2) HK1054238A1 (no)
HR (2) HRP20160074B1 (no)
HU (2) HU230960B1 (no)
IL (1) IL153658A0 (no)
IS (1) IS2985B (no)
LT (2) LT2682397T (no)
LU (1) LU93029I2 (no)
MX (1) MXPA03000587A (no)
NL (1) NL300803I2 (no)
NO (6) NO336718B1 (no)
NZ (3) NZ535408A (no)
OA (1) OA12393A (no)
PL (1) PL213214B1 (no)
PT (2) PT1301519E (no)
SI (2) SI2682397T1 (no)
TR (1) TR200300055T2 (no)
UA (1) UA75889C2 (no)
WO (1) WO2002008241A2 (no)
ZA (1) ZA200210271B (no)

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