JP2017513470A5 - - Google Patents
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- JP2017513470A5 JP2017513470A5 JP2016561659A JP2016561659A JP2017513470A5 JP 2017513470 A5 JP2017513470 A5 JP 2017513470A5 JP 2016561659 A JP2016561659 A JP 2016561659A JP 2016561659 A JP2016561659 A JP 2016561659A JP 2017513470 A5 JP2017513470 A5 JP 2017513470A5
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Applications Claiming Priority (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201461977751P | 2014-04-10 | 2014-04-10 | |
| US61/977,751 | 2014-04-10 | ||
| US201461986479P | 2014-04-30 | 2014-04-30 | |
| US61/986,479 | 2014-04-30 | ||
| US201462058973P | 2014-10-02 | 2014-10-02 | |
| US62/058,973 | 2014-10-02 | ||
| US201462088363P | 2014-12-05 | 2014-12-05 | |
| US62/088,363 | 2014-12-05 | ||
| US201462089730P | 2014-12-09 | 2014-12-09 | |
| US62/089,730 | 2014-12-09 | ||
| US201462090845P | 2014-12-11 | 2014-12-11 | |
| US62/090,845 | 2014-12-11 | ||
| PCT/US2015/024947 WO2015157432A1 (en) | 2014-04-10 | 2015-04-08 | Drug related transgene expression |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020155809A Division JP7093385B2 (ja) | 2014-04-10 | 2020-09-16 | 薬物制御による導入遺伝子の発現 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2017513470A JP2017513470A (ja) | 2017-06-01 |
| JP2017513470A5 true JP2017513470A5 (enExample) | 2018-05-24 |
| JP6765968B2 JP6765968B2 (ja) | 2020-10-07 |
Family
ID=54288361
Family Applications (12)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016561722A Active JP6772068B2 (ja) | 2014-04-10 | 2015-04-08 | 導入遺伝子の遺伝子タグおよびその使用方法 |
| JP2017504604A Active JP6788573B6 (ja) | 2014-04-10 | 2015-04-08 | メトトレキサートによる選択と組み合わせたＳｌｅｅｐｉｎｇ Ｂｅａｕｔｙトランスポゾンによる遺伝子改変Ｔ細胞の製造 |
| JP2016561839A Pending JP2017515464A (ja) | 2014-04-10 | 2015-04-08 | 細胞免疫療法のための方法および組成物 |
| JP2016561659A Active JP6765968B2 (ja) | 2014-04-10 | 2015-04-08 | 薬物制御による導入遺伝子の発現 |
| JP2016561635A Active JP6765967B2 (ja) | 2014-04-10 | 2015-04-08 | 特定の組成を有する遺伝子により改変されたｔ細胞製剤 |
| JP2020105133A Active JP7062720B2 (ja) | 2014-04-10 | 2020-06-18 | 細胞免疫療法のための方法および組成物 |
| JP2020155429A Active JP7148580B2 (ja) | 2014-04-10 | 2020-09-16 | 特定の組成を有する遺伝子により改変されたｔ細胞製剤 |
| JP2020155809A Active JP7093385B2 (ja) | 2014-04-10 | 2020-09-16 | 薬物制御による導入遺伝子の発現 |
| JP2020164326A Active JP7106610B2 (ja) | 2014-04-10 | 2020-09-30 | 導入遺伝子の遺伝子タグおよびその使用方法 |
| JP2022069142A Active JP7542270B2 (ja) | 2014-04-10 | 2022-04-20 | 細胞免疫療法のための方法および組成物 |
| JP2022112278A Active JP7402933B2 (ja) | 2014-04-10 | 2022-07-13 | 導入遺伝子の遺伝子タグおよびその使用方法 |
| JP2022150928A Active JP7508516B2 (ja) | 2014-04-10 | 2022-09-22 | 特定の組成を有する遺伝子により改変されたｔ細胞製剤 |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016561722A Active JP6772068B2 (ja) | 2014-04-10 | 2015-04-08 | 導入遺伝子の遺伝子タグおよびその使用方法 |
| JP2017504604A Active JP6788573B6 (ja) | 2014-04-10 | 2015-04-08 | メトトレキサートによる選択と組み合わせたＳｌｅｅｐｉｎｇ Ｂｅａｕｔｙトランスポゾンによる遺伝子改変Ｔ細胞の製造 |
| JP2016561839A Pending JP2017515464A (ja) | 2014-04-10 | 2015-04-08 | 細胞免疫療法のための方法および組成物 |
Family Applications After (8)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016561635A Active JP6765967B2 (ja) | 2014-04-10 | 2015-04-08 | 特定の組成を有する遺伝子により改変されたｔ細胞製剤 |
| JP2020105133A Active JP7062720B2 (ja) | 2014-04-10 | 2020-06-18 | 細胞免疫療法のための方法および組成物 |
| JP2020155429A Active JP7148580B2 (ja) | 2014-04-10 | 2020-09-16 | 特定の組成を有する遺伝子により改変されたｔ細胞製剤 |
| JP2020155809A Active JP7093385B2 (ja) | 2014-04-10 | 2020-09-16 | 薬物制御による導入遺伝子の発現 |
| JP2020164326A Active JP7106610B2 (ja) | 2014-04-10 | 2020-09-30 | 導入遺伝子の遺伝子タグおよびその使用方法 |
| JP2022069142A Active JP7542270B2 (ja) | 2014-04-10 | 2022-04-20 | 細胞免疫療法のための方法および組成物 |
| JP2022112278A Active JP7402933B2 (ja) | 2014-04-10 | 2022-07-13 | 導入遺伝子の遺伝子タグおよびその使用方法 |
| JP2022150928A Active JP7508516B2 (ja) | 2014-04-10 | 2022-09-22 | 特定の組成を有する遺伝子により改変されたｔ細胞製剤 |
Country Status (19)
| Country | Link |
|---|---|
| US (12) | US10865242B2 (enExample) |
| EP (8) | EP4056201A1 (enExample) |
| JP (12) | JP6772068B2 (enExample) |
| KR (8) | KR102463529B1 (enExample) |
| CN (7) | CN112877291A (enExample) |
| AU (8) | AU2015243849B2 (enExample) |
| BR (3) | BR112016023517A2 (enExample) |
| CA (5) | CA2945308C (enExample) |
| ES (2) | ES2867224T3 (enExample) |
| IL (5) | IL297591B2 (enExample) |
| MX (6) | MX389797B (enExample) |
| MY (4) | MY186846A (enExample) |
| NZ (3) | NZ739448A (enExample) |
| PH (4) | PH12016502010B1 (enExample) |
| RU (5) | RU2729112C2 (enExample) |
| SA (1) | SA516380056B1 (enExample) |
| SG (8) | SG11201608392WA (enExample) |
| WO (5) | WO2015157432A1 (enExample) |
| ZA (3) | ZA201607061B (enExample) |
Families Citing this family (200)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN100548667C (zh) * | 2003-01-20 | 2009-10-14 | 日本瑞翁株式会社 | 层合件及其制造方法 |
| ES2776698T3 (es) | 2012-12-20 | 2020-07-31 | Purdue Research Foundation | Células T que expresan un receptor antigénico quimérico como terapia contra el cáncer |
| PL3071223T3 (pl) * | 2013-11-21 | 2021-08-16 | Autolus Limited | Komórka |
| ES2867224T3 (es) | 2014-04-10 | 2021-10-20 | Seattle Childrens Hospital Dba Seattle Childrens Res Inst | Etiquetas genéticas transgénicas y métodos de uso |
| PT4219687T (pt) | 2014-04-23 | 2024-10-02 | Juno Therapeutics Inc | Métodos para isolamento, cultura, e manipulação genetica de populações de células imunes para terapêutica adotiva |
| GB2540694A (en) | 2014-04-29 | 2017-01-25 | Seattle Children's Hospital (Dba Seattle Children's Res Institute) | CCR5 disruption of cells expressing anti-hiv chimeric antigen receptor (CAR) derived from broadly neutralizing antibodies |
| CN107106610A (zh) | 2014-10-20 | 2017-08-29 | 朱诺治疗学股份有限公司 | 用于过继细胞治疗中的给药的组合物和方法 |
| AU2015339744B2 (en) | 2014-10-31 | 2021-03-25 | The Trustees Of The University Of Pennsylvania | Altering gene expression in CART cells and uses thereof |
| KR101697473B1 (ko) | 2014-11-26 | 2017-01-18 | 주식회사 녹십자랩셀 | T 세포를 이용한 자연살해세포의 배양방법 |
| EP3766895B1 (en) | 2014-12-03 | 2024-07-10 | Juno Therapeutics, Inc. | Methods and compositions for adoptive cell therapy |
| BR112017011914A2 (pt) | 2014-12-05 | 2018-02-27 | Memorial Sloan-Kettering Cancer Center | ?antígeno de maturação de célula b de direcionamento de anticorpos e métodos de uso? |
| FI3240805T3 (fi) | 2014-12-15 | 2025-02-17 | Univ California | Cd19- ja cd20-vasteellinen bispesifinen tai-veräjän kimeerinen antigeenireseptori |
| MA41346A (fr) | 2015-01-12 | 2017-11-21 | Juno Therapeutics Inc | Eléments régulateurs post-transcriptionnels d'hépatite modifiée |
| KR20170128234A (ko) | 2015-01-16 | 2017-11-22 | 주노 쎄러퓨티크스 인코퍼레이티드 | Ror1에 특이적인 항체 및 키메라 항원 수용체 |
| JP6947647B2 (ja) * | 2015-02-24 | 2021-10-13 | ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System | 遺伝子改変ｔ細胞の選択方法 |
| EP4091616A1 (en) | 2015-02-27 | 2022-11-23 | iCell Gene Therapeutics LLC | Chimeric antigen receptors (car) targeting hematologic malignancies, compositions and methods of use thereof |
| CA2981751A1 (en) * | 2015-04-08 | 2016-10-13 | Novartis Ag | Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car)- expressing cell |
| IL287718B2 (en) | 2015-06-25 | 2025-05-01 | Icell Gene Therapeutics Llc | Chimeric antigen receptors (CARs), compositions and methods for using them |
| US11173179B2 (en) | 2015-06-25 | 2021-11-16 | Icell Gene Therapeutics Llc | Chimeric antigen receptor (CAR) targeting multiple antigens, compositions and methods of use thereof |
| JP7162530B2 (ja) | 2015-08-07 | 2022-10-28 | シアトル チルドレンズ ホスピタル （ディービーエイ シアトル チルドレンズ リサーチ インスティテュート） | 固形腫瘍を標的とする二重特異性ｃａｒ ｔ細胞 |
| CN108601849A (zh) * | 2015-09-22 | 2018-09-28 | 尤利乌斯·马克西米利安维尔茨堡大学 | 一种在淋巴细胞中高水平的和稳定的基因转移的方法 |
| BR112018006991A2 (en) | 2015-10-06 | 2018-10-16 | City Of Hope | psca-targeted chimeric antigen receptors |
| EP3364987A4 (en) * | 2015-10-23 | 2019-05-15 | The Regents of the University of Colorado, a Body Corporate | FORECAST AND TREATMENT OF DISCONTINUED CARCINOMENAS |
| KR20180069067A (ko) | 2015-10-30 | 2018-06-22 | 엔비이-테라퓨틱스 아게 | 안티-ror1 항체 |
| WO2017079703A1 (en) * | 2015-11-05 | 2017-05-11 | Juno Therapeutics, Inc. | Vectors and genetically engineered immune cells expressing metabolic pathway modulators and uses in adoptive cell therapy |
| CN108603200B (zh) * | 2015-11-23 | 2022-08-19 | 诺华股份有限公司 | 优化的慢病毒转移载体及其用途 |
| CA3004665C (en) * | 2015-12-14 | 2021-08-24 | GenomeFrontier Therapeutics, Inc. | Transposon system, kit comprising the same, and uses thereof |
| WO2017112877A1 (en) * | 2015-12-22 | 2017-06-29 | Icell Gene Therapeutics, Llc | Chimeric antigen receptors and enhancement of anti-tumor activity |
| CN108848669B (zh) | 2016-01-20 | 2022-06-07 | 斯克利普斯研究所 | Ror1抗体组合物和相关方法 |
| EP3202783A1 (en) * | 2016-02-02 | 2017-08-09 | Ecole Polytechnique Fédérale de Lausanne (EPFL) | Engineered antigen presenting cells and uses thereof |
| EP3430549A1 (en) | 2016-03-16 | 2019-01-23 | Juno Therapeutics, Inc. | Methods for adaptive design of a treatment regimen and related treatments |
| WO2017177149A2 (en) | 2016-04-08 | 2017-10-12 | Purdue Research Foundation | Methods and compositions for car t cell therapy |
| US12060394B2 (en) | 2016-04-28 | 2024-08-13 | The Trustees Of Dartmouth College | Nucleic acid constructs for co-expression of chimeric antigen receptor and transcription factor, cells containing and therapeutic use thereof |
| US12048718B2 (en) * | 2016-06-07 | 2024-07-30 | Max-Delbrück-Centrum für Molekulare Medizin in der Helmholtz-Geminschaft | Chimeric antigen receptor and CAR-T cells that bind BCMA |
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| WO2018075941A1 (en) * | 2016-10-21 | 2018-04-26 | Washington University | Ap4 and methods of promoting t cell activation |
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| BR112019017767A2 (pt) | 2017-02-27 | 2020-04-07 | Juno Therapeutics Inc | composições, artigos de fabricação e métodos relacionados à dosagem em terapia celular |
| CN110582288B (zh) | 2017-02-28 | 2024-09-20 | 恩多塞特公司 | 用于car t细胞疗法的组合物和方法 |
| KR20250029276A (ko) | 2017-03-14 | 2025-03-04 | 주노 쎄러퓨티크스 인코퍼레이티드 | 극저온 보관 방법 |
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