JP2016508134A5 - - Google Patents
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- JP2016508134A5 JP2016508134A5 JP2015549669A JP2015549669A JP2016508134A5 JP 2016508134 A5 JP2016508134 A5 JP 2016508134A5 JP 2015549669 A JP2015549669 A JP 2015549669A JP 2015549669 A JP2015549669 A JP 2015549669A JP 2016508134 A5 JP2016508134 A5 JP 2016508134A5
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- JP
- Japan
- Prior art keywords
- hiv
- pharmaceutical composition
- pharmaceutically acceptable
- composition according
- acceptable salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 239000008194 pharmaceutical composition Substances 0.000 claims 6
- 208000005721 HIV Infections Diseases 0.000 claims 4
- 201000001820 human immunodeficiency virus infectious disease Diseases 0.000 claims 4
- 150000003839 salts Chemical class 0.000 claims 4
- 239000011780 sodium chloride Substances 0.000 claims 4
- 150000001875 compounds Chemical class 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 3
- 239000003112 inhibitor Substances 0.000 claims 3
- 230000002401 inhibitory effect Effects 0.000 claims 3
- 102000015084 HIV Reverse Transcriptase Human genes 0.000 claims 2
- 108010078851 HIV Reverse Transcriptase Proteins 0.000 claims 2
- 239000002777 nucleoside Substances 0.000 claims 2
- 150000003833 nucleoside derivatives Chemical class 0.000 claims 2
- 108010092799 EC 2.7.7.49 Proteins 0.000 claims 1
- 102000033147 ERVK-25 Human genes 0.000 claims 1
- 241000580858 Simian-Human immunodeficiency virus Species 0.000 claims 1
- 239000002259 anti human immunodeficiency virus agent Substances 0.000 claims 1
- 239000003085 diluting agent Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 239000004030 hiv protease inhibitor Substances 0.000 claims 1
- 239000000203 mixture Substances 0.000 claims 1
- 239000002773 nucleotide Substances 0.000 claims 1
- 125000003729 nucleotide group Chemical group 0.000 claims 1
- 238000002560 therapeutic procedure Methods 0.000 claims 1
- SOLUWJRYJLAZCX-LYOVBCGYSA-N OC1=C(C(N2[C@@H](C3)O[C@H]4C[C@@H]2CC4)=O)N3C=C(C(NCc(c(F)cc(F)c2)c2F)=O)C1=O Chemical compound OC1=C(C(N2[C@@H](C3)O[C@H]4C[C@@H]2CC4)=O)N3C=C(C(NCc(c(F)cc(F)c2)c2F)=O)C1=O SOLUWJRYJLAZCX-LYOVBCGYSA-N 0.000 description 1
Claims (9)
- 請求項1に記載の化合物またはその薬学的に受容可能な塩、および薬学的に受容可能なキャリア、希釈剤または賦形剤を含有する、薬学的組成物。
- 1種または1種より多くのさらなる治療剤をさらに含有する、請求項2に記載の薬学的組成物。
- 前記1種または1種より多くのさらなる治療剤は、抗HIV剤である、請求項3に記載の薬学的組成物。
- 前記1種または1種より多くのさらなる治療剤は、HIVプロテアーゼ阻害剤、逆転写酵素のHIV非ヌクレオシド阻害剤、逆転写酵素のHIVヌクレオシド阻害剤、逆転写酵素のHIVヌクレオチド阻害剤、およびこれらの組み合わせからなる群より選択される、請求項4に記載の薬学的組成物。
- HIV感染を有するか、またはHIV感染を有する危険があるヒトにおいて、HIV感染を処置する方法に使用するための、請求項1に記載の化合物またはその薬学的に受容可能な塩。
- HIV感染を有するか、またはHIV感染を有する危険があるヒトにおいて、HIV感染を処置する方法に使用するための、請求項2〜5のいずれか1項に記載の薬学的組成物。
- 医学治療において使用するための、請求項1に記載の化合物またはその薬学的に受容可能な塩。
- 医学治療において使用するための、請求項2〜5のいずれか1項に記載の薬学的組成物。
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201261745375P | 2012-12-21 | 2012-12-21 | |
US61/745,375 | 2012-12-21 | ||
US201361788397P | 2013-03-15 | 2013-03-15 | |
US61/788,397 | 2013-03-15 | ||
US201361845803P | 2013-07-12 | 2013-07-12 | |
US61/845,803 | 2013-07-12 | ||
PCT/US2013/076367 WO2014100323A1 (en) | 2012-12-21 | 2013-12-19 | Polycyclic-carbamoylpyridone compounds and their pharmaceutical use |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016122743A Division JP6411409B2 (ja) | 2012-12-21 | 2016-06-21 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
Publications (3)
Publication Number | Publication Date |
---|---|
JP2016508134A JP2016508134A (ja) | 2016-03-17 |
JP2016508134A5 true JP2016508134A5 (ja) | 2016-08-12 |
JP6028105B2 JP6028105B2 (ja) | 2016-11-16 |
Family
ID=49917297
Family Applications (6)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2015549669A Active JP6028105B2 (ja) | 2012-12-21 | 2013-12-19 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
JP2016122743A Active JP6411409B2 (ja) | 2012-12-21 | 2016-06-21 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
JP2018179844A Active JP6571256B2 (ja) | 2012-12-21 | 2018-09-26 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
JP2019145317A Active JP6933690B2 (ja) | 2012-12-21 | 2019-08-07 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
JP2021134172A Active JP7301918B2 (ja) | 2012-12-21 | 2021-08-19 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
JP2023101636A Pending JP2023134483A (ja) | 2012-12-21 | 2023-06-21 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
Family Applications After (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2016122743A Active JP6411409B2 (ja) | 2012-12-21 | 2016-06-21 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
JP2018179844A Active JP6571256B2 (ja) | 2012-12-21 | 2018-09-26 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
JP2019145317A Active JP6933690B2 (ja) | 2012-12-21 | 2019-08-07 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
JP2021134172A Active JP7301918B2 (ja) | 2012-12-21 | 2021-08-19 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
JP2023101636A Pending JP2023134483A (ja) | 2012-12-21 | 2023-06-21 | 多環式カルバモイルピリドン化合物およびその薬学的用途 |
Country Status (41)
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