|
US3159547A
(en)
|
1963-06-28 |
1964-12-01 |
Abbott Lab |
Method of lowering blood pressure with 4-(2-amino-4-pyrimidylamino)-benzene-sulfonamide
|
|
US3320256A
(en)
|
1965-04-09 |
1967-05-16 |
Hoffmann La Roche |
Fluorinated imidazoo[1, 2-c]pyrimidines and pyrimido[1, 2-c]pyrimidines
|
|
US4166452A
(en)
|
1976-05-03 |
1979-09-04 |
Generales Constantine D J Jr |
Apparatus for testing human responses to stimuli
|
|
US4256108A
(en)
|
1977-04-07 |
1981-03-17 |
Alza Corporation |
Microporous-semipermeable laminated osmotic system
|
|
US4265874A
(en)
|
1980-04-25 |
1981-05-05 |
Alza Corporation |
Method of delivering drug with aid of effervescent activity generated in environment of use
|
|
JPS5845466A
(ja)
|
1981-09-10 |
1983-03-16 |
松下電器産業株式会社 |
空気調和機
|
|
GR80171B
(en)
|
1983-08-29 |
1985-01-02 |
Ciba Geigy Ag |
N-(2-nitrophenyl)-4-aminopyrimidine derivatives process for the preparation thereof and use
|
|
HU192875B
(en)
|
1984-10-05 |
1987-07-28 |
Richter Gedeon Vegyeszet |
Process for preparing 2-pyridinethiol derivatives
|
|
US4866048A
(en)
|
1985-08-02 |
1989-09-12 |
Leo Pharmaceutical Products Ltd. |
Novel vitamin D analogues
|
|
DE3618353A1
(de)
|
1986-05-31 |
1987-12-03 |
Hoechst Ag |
Schaedlingsbekaempfungsmittel auf der basis von aminopyrimidin-derivaten sowie neue aminopyrimidin-verbindungen
|
|
US4968781A
(en)
|
1987-04-02 |
1990-11-06 |
Ciba-Geigy Corporation |
Fiber-reactive dyes comprising a halopyrimidine for which a vinylsulfonyl or the like moiety is attached via a bridge member
|
|
SU1499883A1
(ru)
|
1987-11-24 |
1991-10-23 |
Научно-исследовательский институт фармакологии АМН СССР |
Дихлоргидрат 2,4-бис-(п-трет-бутиланилино)-5-окси-6-метилпиримидина, обладающий анальгетической и противовоспалительной активностью
|
|
KR0144358B1
(ko)
|
1988-04-21 |
1998-07-15 |
피. 라이달 크리스텐슨 |
비타민 d 동족체
|
|
HU206337B
(en)
|
1988-12-29 |
1992-10-28 |
Mitsui Petrochemical Ind |
Process for producing pyrimidine derivatives and pharmaceutical compositions
|
|
US4969781A
(en)
*
|
1989-04-07 |
1990-11-13 |
The B. F. Goodrich Company |
Blind fastener hand tool
|
|
IE63502B1
(en)
|
1989-04-21 |
1995-05-03 |
Zeneca Ltd |
Aminopyrimidine derivatives useful for treating cardiovascular disorders
|
|
US4983608A
(en)
*
|
1989-09-05 |
1991-01-08 |
Hoechst-Roussell Pharmaceuticals, Inc. |
N-substituted-4-pyrimidinamines and pyrimidinediamines
|
|
US5179204A
(en)
|
1989-09-05 |
1993-01-12 |
Hoechst-Roussel Pharmaceuticals Incorporated |
N-substituted-4-pyrimidinamines and pyrimidinediamines
|
|
JPH03127790A
(ja)
|
1989-10-11 |
1991-05-30 |
Morishita Pharmaceut Co Ltd |
Ｎ―（１ｈ―テトラゾール―５―イル）―２―アニリノ―５―ピリミジンカルボキシアミド類及びその合成中間体
|
|
TW224941B
(https=)
|
1989-11-08 |
1994-06-11 |
Yamanouchi Pharma Co Ltd |
|
|
US5532228A
(en)
|
1990-02-06 |
1996-07-02 |
Schering Aktiengesellschaft |
Side-chain homologous vitamin D derivatives, process for their production, pharmaceutical preparations containing these derivatives and their use as pharmaceutical agents
|
|
DE4011682A1
(de)
|
1990-04-06 |
1991-10-10 |
Schering Ag |
24-oxa-derivate in der vitamin d-reihe
|
|
GB9012592D0
(en)
|
1990-06-06 |
1990-07-25 |
Smithkline Beecham Intercredit |
Compounds
|
|
DE4029650A1
(de)
|
1990-09-19 |
1992-03-26 |
Hoechst Ag |
2-anilino-pyrimidine, verfahren zu ihrer herstellung, sie enthaltene mittel und ihre verwendung als fungizide
|
|
JPH04178385A
(ja)
|
1990-11-09 |
1992-06-25 |
Yamanouchi Pharmaceut Co Ltd |
ジケトピリドピラジン誘導体
|
|
DE69219354T2
(de)
|
1991-05-10 |
1997-10-23 |
Takeda Chemical Industries Ltd |
Pyridinderivate, deren Herstellung und Anwendung
|
|
US5200400A
(en)
|
1991-07-12 |
1993-04-06 |
New England Deaconess Hospital Corporation |
Method for inhibiting allograft rejection using photoactivatable nucleotides or nucleosides
|
|
CA2074864A1
(en)
|
1991-07-30 |
1993-01-31 |
Carmen Almansa |
Tetralones with pharmacological activity
|
|
US5728536A
(en)
|
1993-07-29 |
1998-03-17 |
St. Jude Children's Research Hospital |
Jak kinases and regulation of Cytokine signal transduction
|
|
DE4141746A1
(de)
|
1991-12-13 |
1993-06-17 |
Schering Ag |
20-methyl-substituierte vitamin d-derivate
|
|
US5521184A
(en)
|
1992-04-03 |
1996-05-28 |
Ciba-Geigy Corporation |
Pyrimidine derivatives and processes for the preparation thereof
|
|
US5194431A
(en)
|
1992-07-08 |
1993-03-16 |
Wisconsin Alumni Research Foundation |
24-cyclopropane vitamin D derivatives
|
|
TW287160B
(https=)
|
1992-12-10 |
1996-10-01 |
Hoffmann La Roche |
|
|
PL313973A1
(en)
|
1993-10-12 |
1996-08-05 |
Du Pont Merck Pharma |
1 n-alkyl-n-arylopyrimidin amines and their derivatives
|
|
IL112290A
(en)
|
1994-01-12 |
1999-01-26 |
Novartis Ag |
Transformed aryl and the troiryl pyrimidines and herbicides containing them
|
|
CA2150609C
(en)
|
1994-06-01 |
1998-12-08 |
Mikiro Yanaka |
Pyrimidine derivatives and pharmaceutical composition
|
|
US5733932A
(en)
|
1995-01-06 |
1998-03-31 |
The Picower Institute For Medical Research |
Compounds and methods of use to derivatize neighboring lysine residues in proteins under physiological conditions
|
|
US6242434B1
(en)
|
1997-08-08 |
2001-06-05 |
Bone Care International, Inc. |
24-hydroxyvitamin D, analogs and uses thereof
|
|
US5700904A
(en)
|
1995-06-07 |
1997-12-23 |
Eli Lilly And Company |
Preparation of an acylated protein powder
|
|
US6316635B1
(en)
|
1995-06-07 |
2001-11-13 |
Sugen, Inc. |
2-indolinone derivatives as modulators of protein kinase activity
|
|
GB9516121D0
(en)
|
1995-08-05 |
1995-10-04 |
Pfizer Ltd |
Organometallic addition to ketones
|
|
US6069144A
(en)
|
1995-08-24 |
2000-05-30 |
Basf Aktiengesellschaft |
N-heterocyclic compounds, intermediate products used to prepare them, agents containing them and their use in antifungal applications
|
|
GB9523675D0
(en)
*
|
1995-11-20 |
1996-01-24 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
JP4058129B2
(ja)
|
1996-03-18 |
2008-03-05 |
株式会社資生堂 |
ピリジン誘導体及び抗潰瘍剤、抗菌剤
|
|
TW440563B
(en)
|
1996-05-23 |
2001-06-16 |
Hoffmann La Roche |
Aryl pyrimidine derivatives and a pharmaceutical composition thereof
|
|
US6696448B2
(en)
|
1996-06-05 |
2004-02-24 |
Sugen, Inc. |
3-(piperazinylbenzylidenyl)-2-indolinone compounds and derivatives as protein tyrosine kinase inhibitors
|
|
GB9619284D0
(en)
|
1996-09-16 |
1996-10-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
US6004985A
(en)
*
|
1996-10-09 |
1999-12-21 |
Berlex Laboratories, Inc. |
Thio acid derived monocylic N-heterocyclics as anticoagulants
|
|
ES2301194T3
(es)
|
1997-02-05 |
2008-06-16 |
Warner-Lambert Company Llc |
Pirido 2,3-d pirimidinas y 4-aminopirimidinas como inhibidores de la proliferacion celular.
|
|
GB9705361D0
(en)
*
|
1997-03-14 |
1997-04-30 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
US6486185B1
(en)
|
1997-05-07 |
2002-11-26 |
Sugen, Inc. |
3-heteroarylidene-2-indolinone protein kinase inhibitors
|
|
US6316429B1
(en)
|
1997-05-07 |
2001-11-13 |
Sugen, Inc. |
Bicyclic protein kinase inhibitors
|
|
US6987113B2
(en)
|
1997-06-11 |
2006-01-17 |
Sugen, Inc. |
Tyrosine kinase inhibitors
|
|
SE9702401D0
(sv)
|
1997-06-19 |
1997-06-19 |
Astra Ab |
Pharmaceutical use
|
|
GB9718913D0
(en)
|
1997-09-05 |
1997-11-12 |
Glaxo Group Ltd |
Substituted oxindole derivatives
|
|
US6133305A
(en)
|
1997-09-26 |
2000-10-17 |
Sugen, Inc. |
3-(substituted)-2-indolinones compounds and use thereof as inhibitors of protein kinase activity
|
|
US6093820A
(en)
|
1997-10-02 |
2000-07-25 |
Taro Pharmaceutical Industries Ltd. |
Method and reagents for N-alkylating ureides
|
|
US6022884A
(en)
*
|
1997-11-07 |
2000-02-08 |
Amgen Inc. |
Substituted pyridine compounds and methods of use
|
|
GB9723859D0
(en)
|
1997-11-12 |
1998-01-07 |
Zeneca Ltd |
Compound,composition and use
|
|
DE19750701A1
(de)
|
1997-11-15 |
1999-05-20 |
Dystar Textilfarben Gmbh & Co |
Verfahren zur Umsetzung von fluorsubstituierten Heterocyclen mit Aminen in Gegenwart von Phasentransfer-Katalysatoren
|
|
AU1507199A
(en)
|
1997-12-15 |
1999-07-05 |
Yamanouchi Pharmaceutical Co., Ltd. |
Novel pyrimidine-5-carboxamide derivatives
|
|
KR20010033811A
(ko)
|
1997-12-31 |
2001-04-25 |
토마스 안 빅토리아 |
2차 및 3차 아민을 함유하는 약제의 물에 용해가능한프로드럭 및 그것의 제조방법
|
|
US6069141A
(en)
|
1998-02-13 |
2000-05-30 |
Pharmacia & Upjohn Company |
Substituted aminophenyl isoxazoline derivatives useful as antimicrobials
|
|
BR9908004A
(pt)
|
1998-02-17 |
2001-12-18 |
Tularik Inc |
Composto, composição e método para prevençãoou supressão de uma infecção viral
|
|
EP1064289A1
(en)
|
1998-03-18 |
2001-01-03 |
Ariad Pharmaceuticals, Inc. |
Heterocyclic signal transduction inhibitors, compositions containing them
|
|
CZ299380B6
(cs)
|
1998-03-27 |
2008-07-09 |
Janssen Pharmaceutica N. V. |
Pyrimidinová sloucenina, použití této slouceniny pro prípravu léciva, farmaceutický prostredek tutoslouceninu obsahující, zpusob prípravy tohoto prostredku a uvedené slouceniny a kombinace a produktuvedenou slouceninu obsahující
|
|
BRPI9909191B8
(pt)
|
1998-03-27 |
2021-07-06 |
Janssen Pharmaceutica Nv |
derivados de pirimidina inibidores do hiv, seu uso e composição farmacêutica que os compreende
|
|
GB9806739D0
(en)
|
1998-03-28 |
1998-05-27 |
Univ Newcastle Ventures Ltd |
Cyclin dependent kinase inhibitors
|
|
CA2333927A1
(en)
*
|
1998-04-01 |
1999-10-07 |
Dupont Pharmaceuticals Company |
Pyrimidines and triazines as integrin antagonists
|
|
WO1999052942A2
(en)
|
1998-04-15 |
1999-10-21 |
Genset |
Genomic sequence of the 5-lipoxygenase-activating protein (flap), polymorphic markers thereof and methods for detection of asthma
|
|
CN1548436A
(zh)
|
1998-05-22 |
2004-11-24 |
ʷ��˿�������ȳ�ķ����˾ |
新的2-烷基取代咪唑化合物
|
|
WO2000000202A1
(en)
|
1998-06-30 |
2000-01-06 |
Parker Hughes Institute |
Method for inhibiting c-jun expression using jak-3 inhibitors
|
|
US6313129B1
(en)
|
1998-08-21 |
2001-11-06 |
Hughes Institute |
Therapeutic compounds
|
|
ES2274634T3
(es)
|
1998-08-29 |
2007-05-16 |
Astrazeneca Ab |
Compuestos de pirimidina.
|
|
DE19851421A1
(de)
|
1998-11-07 |
2000-05-11 |
Boehringer Ingelheim Pharma |
Neue Pyrimidine, deren Herstellung und Verwendung
|
|
HRP20080359B1
(hr)
|
1998-11-10 |
2016-01-01 |
Janssen Pharmaceutica N.V. |
PIRIMIDINI KOJI INHIBIRAJU REPLIKACIJU HIV-a
|
|
JP2002529444A
(ja)
|
1998-11-12 |
2002-09-10 |
アリアド・ファーマシューティカルズ・インコーポレイテッド |
二環式シグナル伝達阻害剤、それを含む組成物とその用途
|
|
US6127376A
(en)
|
1998-12-04 |
2000-10-03 |
Berlex Laboratories, Inc. |
Aryl and heterocyclyl substituted pyrimidine derivatives as anti-coagulants
|
|
GB9828511D0
(en)
*
|
1998-12-24 |
1999-02-17 |
Zeneca Ltd |
Chemical compounds
|
|
US6841567B1
(en)
|
1999-02-12 |
2005-01-11 |
Cephalon, Inc. |
Cyclic substituted fused pyrrolocarbazoles and isoindolones
|
|
US6673908B1
(en)
|
1999-02-22 |
2004-01-06 |
Nuvelo, Inc. |
Tumor necrosis factor receptor 2
|
|
GB9904995D0
(en)
|
1999-03-04 |
1999-04-28 |
Glaxo Group Ltd |
Substituted aza-oxindole derivatives
|
|
US6624171B1
(en)
|
1999-03-04 |
2003-09-23 |
Smithkline Beecham Corporation |
Substituted aza-oxindole derivatives
|
|
US6080747A
(en)
|
1999-03-05 |
2000-06-27 |
Hughes Institute |
JAK-3 inhibitors for treating allergic disorders
|
|
SE9901079D0
(sv)
|
1999-03-23 |
1999-03-23 |
Astra Ab |
Novel compounds
|
|
US6518286B1
(en)
|
1999-03-26 |
2003-02-11 |
Astrazeneca Ab |
Compounds
|
|
GB9907658D0
(en)
|
1999-04-06 |
1999-05-26 |
Zeneca Ltd |
Chemical compounds
|
|
AU4198400A
(en)
|
1999-04-06 |
2000-10-23 |
Krenitsky Pharmaceuticals Inc. |
Neurotrophic thio substituted pyrimidines
|
|
US7125875B2
(en)
|
1999-04-15 |
2006-10-24 |
Bristol-Myers Squibb Company |
Cyclic protein tyrosine kinase inhibitors
|
|
DE19917785A1
(de)
|
1999-04-20 |
2000-10-26 |
Bayer Ag |
2,4-Diamino-pyrimidin-Derivate
|
|
WO2000076980A1
(en)
|
1999-06-10 |
2000-12-21 |
Yamanouchi Pharmaceutical Co., Ltd. |
Novel nitrogen-contaiing heterocyclic derivatives or salts thereof
|
|
GB9914258D0
(en)
|
1999-06-18 |
1999-08-18 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
AU5636900A
(en)
|
1999-06-30 |
2001-01-31 |
Merck & Co., Inc. |
Src kinase inhibitor compounds
|
|
TWI262914B
(en)
|
1999-07-02 |
2006-10-01 |
Agouron Pharma |
Compounds and pharmaceutical compositions for inhibiting protein kinases
|
|
GB9918035D0
(en)
|
1999-07-30 |
1999-09-29 |
Novartis Ag |
Organic compounds
|
|
EP1409487A1
(en)
|
1999-09-15 |
2004-04-21 |
Warner-Lambert Company Llc |
Pteridinones as kinase inhibitors
|
|
DE19945982A1
(de)
|
1999-09-24 |
2001-03-29 |
Knoll Ag |
Geschwindigkeitsbestimmte Partikel
|
|
CA2384188C
(en)
|
1999-09-24 |
2008-06-17 |
Janssen Pharmaceutica N.V. |
Antiviral compositions
|
|
IL148903A0
(en)
|
1999-09-30 |
2002-09-12 |
Neurogen Corp |
Certain alkylene diamine-substituted heterocycles
|
|
KR100317935B1
(ko)
|
1999-10-20 |
2001-12-22 |
유승필 |
대사성 골질환 치료용 약제조성물 및 이의 제조방법
|
|
GB9924862D0
(en)
|
1999-10-20 |
1999-12-22 |
Celltech Therapeutics Ltd |
Chemical compounds
|
|
AU1026901A
(en)
|
1999-10-29 |
2001-05-08 |
Syngenta Participations Ag |
Novel herbicides
|
|
JP2003518023A
(ja)
|
1999-11-30 |
2003-06-03 |
パーカー ヒューズ インスティテュート |
トロンビン誘導血小板凝集の阻害剤
|
|
EP1382339B1
(en)
|
1999-12-10 |
2007-12-05 |
Pfizer Products Inc. |
Compositions containing pyrrolo ¬2,3-d pyrimidine derivatives
|
|
WO2001046196A1
(en)
|
1999-12-21 |
2001-06-28 |
Sugen, Inc. |
4-substituted 7-aza-indolin-2-ones and their use as protein kinase inhibitors
|
|
US20020065270A1
(en)
|
1999-12-28 |
2002-05-30 |
Moriarty Kevin Joseph |
N-heterocyclic inhibitors of TNF-alpha expression
|
|
CA2394727A1
(en)
|
1999-12-28 |
2001-07-05 |
Pharmacopeia, Inc. |
Pyrimidine and triazine kinase inhibitors
|
|
US6362172B2
(en)
|
2000-01-20 |
2002-03-26 |
Bristol-Myers Squibb Company |
Water soluble prodrugs of azole compounds
|
|
IL150763A0
(en)
|
2000-01-24 |
2003-02-12 |
Genzyme Corp |
Jak/stat inhibitors and pharmaceutical compositions containing the same
|
|
CA2369076A1
(en)
|
2000-02-05 |
2001-08-09 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compositions useful as inhibitors of erk
|
|
HUP0202332A2
(en)
|
2000-02-05 |
2002-10-28 |
Vertex Pharma |
Pyrazole compositions useful as inhibitors of erk
|
|
EP1257546A1
(en)
|
2000-02-17 |
2002-11-20 |
Amgen Inc. |
Kinase inhibitors
|
|
GB0004890D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
GB0004886D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
GB0004888D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
GB0004887D0
(en)
|
2000-03-01 |
2000-04-19 |
Astrazeneca Uk Ltd |
Chemical compounds
|
|
US6525051B2
(en)
|
2000-03-27 |
2003-02-25 |
Schering Aktiengesellschaft |
N-heterocyclic derivatives as NOS inhibitors
|
|
AR028261A1
(es)
|
2000-03-28 |
2003-04-30 |
Wyeth Corp |
Inhibidores triciclicos de la proteina quinasa
|
|
US6608048B2
(en)
|
2000-03-28 |
2003-08-19 |
Wyeth Holdings |
Tricyclic protein kinase inhibitors
|
|
WO2001085700A2
(en)
|
2000-05-08 |
2001-11-15 |
Janssen Pharmaceutica N.V. |
Hiv replication inhibiting pyrimidines and triazines
|
|
JP4969010B2
(ja)
|
2000-05-08 |
2012-07-04 |
ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ |
Ｈｉｖ複製阻害性ピリミジンのプロドラッグ
|
|
IL152771A0
(en)
|
2000-06-26 |
2003-06-24 |
Pfizer Prod Inc |
PYRROLO(2,3-d) PYRIMIDINE COMPOUNDS AS IMMUNOSUPPRESSIVE AGENTS
|
|
GB0016877D0
(en)
|
2000-07-11 |
2000-08-30 |
Astrazeneca Ab |
Chemical compounds
|
|
US20050009876A1
(en)
|
2000-07-31 |
2005-01-13 |
Bhagwat Shripad S. |
Indazole compounds, compositions thereof and methods of treatment therewith
|
|
AU2001283381A1
(en)
|
2000-08-18 |
2002-03-04 |
3M Innovative Properties Company |
Fluoroalkyl (meth)acrylate copolymer coating compositions
|
|
EP1317450B1
(en)
|
2000-09-15 |
2006-11-22 |
Vertex Pharmaceuticals Incorporated |
Pyrazole compounds useful as protein kinase inhibitors
|
|
JP4269144B2
(ja)
|
2000-10-02 |
2009-05-27 |
エモリー ユニバーシティ |
自己免疫疾患および炎症障害の処置のためのトリプトリドアナログ
|
|
US6448401B1
(en)
|
2000-11-20 |
2002-09-10 |
Bristol-Myers Squibb Company |
Process for water soluble azole compounds
|
|
AU2001229722A1
(en)
|
2000-11-29 |
2002-06-11 |
Parker Hughes Institute |
Inhibitors of thrombin induced platelet aggregation
|
|
US20020137755A1
(en)
|
2000-12-04 |
2002-09-26 |
Bilodeau Mark T. |
Tyrosine kinase inhibitors
|
|
US20020115173A1
(en)
|
2000-12-11 |
2002-08-22 |
Children's Medical Center Corporation |
Short peptides from the 'A-region' of protein kinases which selectively modulate protein kinase activity
|
|
AU2002228922A1
(en)
|
2000-12-12 |
2002-06-24 |
Cytovia, Inc. |
Substituted 2-aryl-4-arylaminopyrimidines and analogs as activators of caspases and inducers of apoptosis and the use thereof
|
|
EP1349852A2
(en)
|
2000-12-20 |
2003-10-08 |
Sugen, Inc. |
4-(hetero)aryl substituted indolinones
|
|
EP1343782B1
(en)
|
2000-12-21 |
2009-05-06 |
SmithKline Beecham Corporation |
Pyrimidineamines as angiogenesis modulators
|
|
NZ526472A
(en)
|
2000-12-21 |
2004-04-30 |
Vertex Pharma |
Pyrazole compounds useful as protein kinase inhibitors
|
|
US20040102455A1
(en)
|
2001-01-30 |
2004-05-27 |
Burns Christopher John |
Method of inhibiting kinases
|
|
AUPR279101A0
(en)
|
2001-01-30 |
2001-02-22 |
Cytopia Pty Ltd |
Protein kinase signalling
|
|
AU2002258400A1
(en)
|
2001-02-16 |
2002-08-28 |
Tularik Inc. |
Methods of using pyrimidine-based antiviral agents
|
|
GB0103926D0
(en)
|
2001-02-17 |
2001-04-04 |
Astrazeneca Ab |
Chemical compounds
|
|
EP1423388B1
(en)
|
2001-02-20 |
2008-12-03 |
AstraZeneca AB |
2-arylamino-pyrimidines for the treatment of gsk3-related disorders
|
|
GB2373186A
(en)
|
2001-02-23 |
2002-09-18 |
Astrazeneca Ab |
Pharmaceutical combinations of a CCR3 antagonist and a compound which is usefulreatment of asthma, allergic disease or inflammation
|
|
PL364625A1
(en)
|
2001-02-23 |
2004-12-13 |
Merck & Co, Inc. |
N-substituted nonaryl-heterocyclic nmda/nr2b antagonists
|
|
DE60239097D1
(de)
|
2001-03-02 |
2011-03-17 |
Gpc Biotech Ag |
Drei-hybrid-assaysystem
|
|
KR100874791B1
(ko)
|
2001-05-29 |
2008-12-18 |
바이엘 쉐링 파마 악티엔게젤샤프트 |
Ｃｄｋ-억제 피리미딘, 그의 제조방법 및 약제로서의 용도
|
|
US6762179B2
(en)
|
2001-05-31 |
2004-07-13 |
Vertex Pharmaceuticals Incorporated |
Thiazole compounds useful as inhibitors of protein kinase
|
|
US7301023B2
(en)
|
2001-05-31 |
2007-11-27 |
Pfizer Inc. |
Chiral salt resolution
|
|
CA2446756C
(en)
|
2001-06-01 |
2011-03-08 |
Vertex Pharmaceuticals Incorporated |
Thiazole compounds useful as inhibitors of protein kinase
|
|
US6825190B2
(en)
|
2001-06-15 |
2004-11-30 |
Vertex Pharmaceuticals Incorporated |
Protein kinase inhibitors and uses thereof
|
|
JP2005500294A
(ja)
|
2001-06-19 |
2005-01-06 |
ブリストル−マイヤーズ スクイブ カンパニー |
ホスホジエステラーゼ７に対するピリミジン阻害剤
|
|
EP1408978A4
(en)
|
2001-06-21 |
2005-07-13 |
Ariad Pharma Inc |
NOVEL PHENYLAMINO-PYRIMIDINES AND THEIR USE
|
|
GB0115109D0
(en)
|
2001-06-21 |
2001-08-15 |
Aventis Pharma Ltd |
Chemical compounds
|
|
KR100875380B1
(ko)
|
2001-06-23 |
2008-12-23 |
아벤티스 파마슈티칼스 인크. |
단백질 키나제 억제제로서의 피롤로피리미딘
|
|
GB0115393D0
(en)
|
2001-06-23 |
2001-08-15 |
Aventis Pharma Ltd |
Chemical compounds
|
|
US20030139435A1
(en)
|
2001-06-26 |
2003-07-24 |
Gulzar Ahmed |
N-heterocyclic inhibitors of TNF-alpha expression
|
|
JO3429B1
(ar)
|
2001-08-13 |
2019-10-20 |
Janssen Pharmaceutica Nv |
مشتقات برميدينات مثبطة فيروس الايدز
|
|
US6939874B2
(en)
|
2001-08-22 |
2005-09-06 |
Amgen Inc. |
Substituted pyrimidinyl derivatives and methods of use
|
|
US7115617B2
(en)
|
2001-08-22 |
2006-10-03 |
Amgen Inc. |
Amino-substituted pyrimidinyl derivatives and methods of use
|
|
US7070996B2
(en)
|
2001-08-31 |
2006-07-04 |
Rigel Pharmaceuticals, Inc. |
Production of cultured human mast cells and basophils for high throughput small molecule drug discovery
|
|
US6433018B1
(en)
|
2001-08-31 |
2002-08-13 |
The Research Foundation Of State University Of New York |
Method for reducing hypertrophy and ischemia
|
|
WO2003020698A2
(en)
|
2001-09-06 |
2003-03-13 |
Prochon Biotech Ltd. |
Protein tyrosine kinase inhibitors
|
|
EP1436259A1
(en)
|
2001-09-10 |
2004-07-14 |
Congxin Liang |
3-(4,5,6,7-tetrahydroindol-2-ylmethylidiene)-2-indolinone derivatives as kinase inhibitors
|
|
WO2003030909A1
(en)
|
2001-09-25 |
2003-04-17 |
Bayer Pharmaceuticals Corporation |
2- and 4-aminopyrimidines n-substtituded by a bicyclic ring for use as kinase inhibitors in the treatment of cancer
|
|
WO2003026664A1
(en)
*
|
2001-09-26 |
2003-04-03 |
Bayer Corporation |
2-phenylamino-4- (5-pyrazolylamino) -pyramidine derivatives as kinase inhibitors, in particular, src kinase inhibitors
|
|
WO2003040141A1
(en)
*
|
2001-09-28 |
2003-05-15 |
Bayer Pharmaceuticals Corporation |
Oxazolyl-phenyl-2,4-diamino-pyrimidine compounds and methods for treating hyperproliferative disorders
|
|
EP1453516A2
(de)
|
2001-10-17 |
2004-09-08 |
Boehringer Ingelheim Pharma GmbH & Co.KG |
5-substituierte 4-amino-2-phenylamino-pyrimdinderivate und ihre verwendung als beta-amyloid modulatoren
|
|
ATE407678T1
(de)
|
2001-10-17 |
2008-09-15 |
Boehringer Ingelheim Pharma |
Pyrimidinderivate, arzneimittel enthaltend diese verbindungen, deren verwendung und verfahren zu ihrer herstellung
|
|
US6897208B2
(en)
|
2001-10-26 |
2005-05-24 |
Aventis Pharmaceuticals Inc. |
Benzimidazoles
|
|
US7589105B2
(en)
|
2001-11-28 |
2009-09-15 |
Btg International Limited |
Preventives or remedies for alzheimer's disease, or amyloid protein fibril-formation inhibitors, which include a nitrogen-containing heteroaryl compound
|
|
PY0228255A
(es)
|
2001-12-06 |
2004-06-01 |
Pfizer Prod Inc |
Compuestos cristalinos novedosos
|
|
SE0104140D0
(sv)
|
2001-12-07 |
2001-12-07 |
Astrazeneca Ab |
Novel Compounds
|
|
AU2002367172A1
(en)
*
|
2001-12-21 |
2003-07-15 |
Bayer Pharmaceuticals Corporation |
2,4-diamino-pyrimidine derivative compounds as inhibitors of prolylpeptidase, inducers of apoptosis and cancer treatment agents
|
|
US20030158195A1
(en)
|
2001-12-21 |
2003-08-21 |
Cywin Charles L. |
1,6 naphthyridines useful as inhibitors of SYK kinase
|
|
JP4469179B2
(ja)
|
2002-01-23 |
2010-05-26 |
バイエル ファーマセチカル コーポレーション |
Ｒｈｏキナーゼ阻害剤としてのピリミジン誘導体
|
|
TWI329105B
(en)
|
2002-02-01 |
2010-08-21 |
Rigel Pharmaceuticals Inc |
2,4-pyrimidinediamine compounds and their uses
|
|
US6998391B2
(en)
|
2002-02-07 |
2006-02-14 |
Supergen.Inc. |
Method for treating diseases associated with abnormal kinase activity
|
|
CA2476281A1
(en)
|
2002-02-08 |
2003-08-14 |
Smithkline Beecham Corporation |
Pyrimidine compounds
|
|
AU2003220970A1
(en)
|
2002-03-01 |
2003-09-16 |
Smithkline Beecham Corporation |
Diamino-pyrimidines and their use as angiogenesis inhibitors
|
|
US7288547B2
(en)
|
2002-03-11 |
2007-10-30 |
Schering Ag |
CDK-inhibitory 2-heteroaryl-pyrimidines, their production and use as pharmaceutical agents
|
|
AU2003212282A1
(en)
|
2002-03-11 |
2003-09-22 |
Schering Aktiengesellschaft |
Cdk inhibiting 2-heteroaryl pyrimidine, the production thereof, and use thereof as a medicament
|
|
GB0206215D0
(en)
|
2002-03-15 |
2002-05-01 |
Novartis Ag |
Organic compounds
|
|
HRP20040853A2
(en)
|
2002-03-20 |
2004-12-31 |
Bristol Myers Squibb Co |
Phosphate prodrugs of fluorooxindoles
|
|
AU2003301758A1
(en)
|
2002-05-06 |
2004-05-25 |
Bayer Pharmaceuticals Corporation |
Use of pyrimidine derivates for the manifacture of a medicament for the treatment of hyper-proliferative disorders
|
|
WO2003095448A1
(en)
|
2002-05-06 |
2003-11-20 |
Bayer Pharmaceuticals Corporation |
Pyridinyl amino pyrimidine derivatives useful for treating hyper-proliferative disorders
|
|
AR039540A1
(es)
|
2002-05-13 |
2005-02-23 |
Tibotec Pharm Ltd |
Compuestos microbicidas con contenido de pirimidina o triazina
|
|
JP2005528443A
(ja)
|
2002-05-30 |
2005-09-22 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Ｊａｋキナーゼおよびｃｄｋ２プロテインキナーゼのインヒビター
|
|
AU2003236720A1
(en)
|
2002-06-14 |
2003-12-31 |
Altana Pharma Ag |
Substituted diaminopyrimidines
|
|
PL374963A1
(en)
|
2002-06-17 |
2005-11-14 |
Smithkline Beecham Corporation |
Chemical process
|
|
AU2003244098A1
(en)
|
2002-06-28 |
2004-01-19 |
Yamanouchi Pharmaceutical Co., Ltd. |
Diaminopyrimidinecarboxa mide derivative
|
|
US6758434B2
(en)
*
|
2002-07-03 |
2004-07-06 |
Kimberly-Clark Worldwide, Inc. |
Dispenser for multiple rolls of sheet material
|
|
EP1523607B1
(en)
|
2002-07-23 |
2011-08-24 |
Welldynamics, B.V. |
Subterranean well pressure and temperature measurement
|
|
ES2445208T3
(es)
|
2002-07-29 |
2014-02-28 |
Rigel Pharmaceuticals, Inc. |
Compuestos de 2,4-pirimidindiamina para uso en métodos para tratar o prevenir enfermedades autoinmunitarias
|
|
AU2003249539A1
(en)
|
2002-08-13 |
2004-02-25 |
Warner-Lambert Company Llc |
Cyclic compounds containing zinc binding groups as matrix metalloproteinase inhibitors
|
|
MXPA05001804A
(es)
|
2002-08-14 |
2005-05-27 |
Vertex Pharma |
Inhibidores de proteinas cinasas y usos de los mismos.
|
|
DE10243291B4
(de)
*
|
2002-09-18 |
2015-04-30 |
Mann + Hummel Gmbh |
Ventil, insbesondere für den Ölkreislauf einer Brennkraftmaschine
|
|
JP2006512314A
(ja)
|
2002-11-01 |
2006-04-13 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
Ｊａｋインヒビターおよび他のプロテインキナーゼインヒビターとしての組成物の使用
|
|
EP1562938B1
(en)
|
2002-11-04 |
2007-08-29 |
Vertex Pharmaceuticals Incorporated |
Heteroaryl-pyrimidine derivatives as jak inhibitors
|
|
EP1560824A1
(en)
|
2002-11-05 |
2005-08-10 |
Vertex Pharmaceuticals Incorporated |
Compounds useful as inhibitors of jak and other protein kinases
|
|
GB0226582D0
(en)
|
2002-11-14 |
2002-12-18 |
Cyclacel Ltd |
Anti-viral compounds
|
|
GB0226583D0
(en)
|
2002-11-14 |
2002-12-18 |
Cyclacel Ltd |
Compounds
|
|
CL2003002353A1
(es)
|
2002-11-15 |
2005-02-04 |
Vertex Pharma |
Compuestos derivados de diaminotriazoles, inhibidores d ela proteina quinasa; composicion farmaceutica; procedimiento de preparacion; y su uso del compuesto en el tratamiento de enfermedades de desordenes alergicos, proliferacion, autoinmunes, condic
|
|
KR100678800B1
(ko)
|
2002-11-21 |
2007-02-05 |
화이자 프로덕츠 인코포레이티드 |
3-아미노-피페리딘 유도체 및 그의 제조 방법
|
|
NZ539901A
(en)
|
2002-11-26 |
2007-09-28 |
Pfizer Prod Inc |
Method of treatment of transplant rejection
|
|
BR0316680A
(pt)
|
2002-11-28 |
2005-10-18 |
Schering Ag |
Pirimidinas inibidoras de chk, pdk e akt, sua produção e uso como agentes farmacêuticos
|
|
AU2002350719A1
(en)
|
2002-11-29 |
2004-06-23 |
Janssen Pharmaceutica N.V. |
Pharmaceutical compositions comprising a basic respectively acidic drug compound, a surfactant and a physiologically tolerable water-soluble acid respectively base
|
|
JP2006514021A
(ja)
|
2002-12-09 |
2006-04-27 |
ザ・ボード・オブ・リージェンツ・オブ・ザ・ユニバーシティ・オブ・テキサス・システム |
Ｊａｎｕｓチロシンキナーゼ３（Ｊａｋ３）を選択的に阻害するための方法
|
|
JPWO2004054617A1
(ja)
|
2002-12-13 |
2006-04-20 |
協和醗酵工業株式会社 |
中枢疾患の予防および／または治療剤
|
|
US7226919B2
(en)
|
2002-12-18 |
2007-06-05 |
Vertex Pharmaceuticals Inc. |
Compositions useful as inhibitors of protein kinases
|
|
US7098332B2
(en)
|
2002-12-20 |
2006-08-29 |
Hoffmann-La Roche Inc. |
5,8-Dihydro-6H-pyrido[2,3-d]pyrimidin-7-ones
|
|
UA80767C2
(en)
|
2002-12-20 |
2007-10-25 |
Pfizer Prod Inc |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
|
ATE440087T1
(de)
|
2003-01-30 |
2009-09-15 |
Boehringer Ingelheim Pharma |
2,4-diaminopyrimidinderivate, die sich als inhibitoren von pkc-theta eignen
|
|
BRPI0407329A
(pt)
|
2003-02-07 |
2006-01-10 |
Janssen Pharmaceutica Nv |
Derivados de pirimidina para a prevenção de infecção de hiv
|
|
ES2325440T3
(es)
|
2003-02-20 |
2009-09-04 |
Smithkline Beecham Corporation |
Compuestos de pirimidina.
|
|
CL2004000303A1
(es)
|
2003-02-20 |
2005-04-08 |
Tibotec Pharm Ltd |
Compuestos derivados de pirimidinas y triazinas; proceso de preparacion; composicion farmaceutica; y su uso para inhibir la replicacion del vih.
|
|
GB0305929D0
(en)
|
2003-03-14 |
2003-04-23 |
Novartis Ag |
Organic compounds
|
|
WO2004092154A1
(en)
|
2003-04-03 |
2004-10-28 |
Vertex Pharmaceuticals Incorporated |
Compositions useful as inhibitors of protein kinases
|
|
CA2524221A1
(en)
|
2003-04-30 |
2004-11-18 |
The Institutes For Pharmaceutical Discovery, Llc |
Substituted heteroaryls as inhibitors of protein tyrosine phosphatases
|
|
GB0311274D0
(en)
|
2003-05-16 |
2003-06-18 |
Astrazeneca Ab |
Chemical compounds
|
|
GB0311276D0
(en)
|
2003-05-16 |
2003-06-18 |
Astrazeneca Ab |
Chemical compounds
|
|
US7915293B2
(en)
|
2003-05-30 |
2011-03-29 |
Rigel Pharmaceuticals, Inc. |
Ubiquitin ligase inhibitors
|
|
CA2531401A1
(en)
|
2003-07-10 |
2005-01-27 |
Neurogen Corporation |
Substituted heterocyclic diarylamine analogues
|
|
MXPA06000540A
(es)
|
2003-07-16 |
2006-03-30 |
Janssen Pharmaceutica Nv |
Derivados de triazolopirimidinas como inhibidores de la glucogeno sintasa cinasa 3.
|
|
EP1781659B1
(en)
|
2003-07-16 |
2008-11-05 |
Janssen Pharmaceutica N.V. |
Triazolopyrimidine derivatives as glycogen synthase kinase 3 inhibitors
|
|
AU2004259346A1
(en)
|
2003-07-22 |
2005-02-03 |
Neurogen Corporation |
Substituted pyridin-2-ylamine analogues
|
|
US7442698B2
(en)
|
2003-07-24 |
2008-10-28 |
Amgen Inc. |
Substituted heterocyclic compounds and methods of use
|
|
EP1651599A4
(en)
|
2003-07-24 |
2008-09-24 |
Merck & Co Inc |
TYROSINE KINASE INHIBITORS
|
|
EP1648875A1
(en)
|
2003-07-30 |
2006-04-26 |
Cyclacel Limited |
2-aminophenyl-4-phenylpyrimidines as kinase inhibitors
|
|
BRPI0413018B8
(pt)
|
2003-07-30 |
2021-05-25 |
Rigel Pharmaceuticals Inc |
composto, e, uso de um composto
|
|
WO2005013982A1
(en)
|
2003-08-06 |
2005-02-17 |
Vertex Pharmaceuticals Incorporated |
Aminotriazole compounds useful as inhibitors of protein kinases
|
|
WO2005013996A2
(en)
|
2003-08-07 |
2005-02-17 |
Rigel Pharmaceuticals, Inc. |
2,4-pyrimidinediamine compounds and uses as anti-proliferative agents
|
|
OA13235A
(en)
|
2003-08-14 |
2006-12-13 |
Pfizer |
Piperazine derivatives for the treatment of HIV infections.
|
|
NZ585188A
(en)
|
2003-08-15 |
2011-09-30 |
Novartis Ag |
2,4-Pyrimidinediamines useful in the treatment of neoplastic diseases, inflammatory and immune system disorders
|
|
AR045595A1
(es)
|
2003-09-04 |
2005-11-02 |
Vertex Pharma |
Composiciones utiles como inhibidores de proteinas quinasas
|
|
WO2005028467A1
(en)
|
2003-09-15 |
2005-03-31 |
Anadys Pharmaceuticals, Inc. |
Antibacterial 3,5-diaminopiperidine-substitute aromatic and heteroaromatic compounds
|
|
GB0321710D0
(en)
|
2003-09-16 |
2003-10-15 |
Novartis Ag |
Organic compounds
|
|
MXPA06003054A
(es)
|
2003-09-18 |
2006-05-31 |
Novartis Ag |
2,4-di-(fenil-amino)-pirimidinas utiles en el tratamiento de trastornos proliferativos.
|
|
WO2005027848A2
(en)
|
2003-09-19 |
2005-03-31 |
Barnes-Jewish Hospital |
Methods for screening osteogenic compounds targeting syk kinase and/or vav3 and uses of syk modulators and/or vav modulators
|
|
DE602004031641D1
(de)
|
2003-09-25 |
2011-04-14 |
Janssen Pharmaceutica Nv |
Die replikation von hiv hemmende purinderivate
|
|
EP1682545B1
(en)
|
2003-10-03 |
2007-12-12 |
Pfizer Limited |
Imidazopyridine substituted tropane derivatives with ccr5 receptor antagonist activity for the treatment of hiv and inflammation
|
|
DE10349423A1
(de)
|
2003-10-16 |
2005-06-16 |
Schering Ag |
Sulfoximinsubstituierte Parimidine als CDK- und/oder VEGF-Inhibitoren, deren Herstellung und Verwendung als Arzneimittel
|
|
JP2007515400A
(ja)
|
2003-11-28 |
2007-06-14 |
ノバルティス アクチエンゲゼルシャフト |
タンパク質キナーゼ依存性疾患の処置におけるジアリール尿素誘導体
|
|
MY141255A
(en)
|
2003-12-11 |
2010-03-31 |
Memory Pharm Corp |
Phosphodiesterase 4 inhibitors, including n-substituted diarylamine analogs
|
|
JP2007514775A
(ja)
|
2003-12-19 |
2007-06-07 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
１−（２，４−ピリミジンジアミノ）−２−シクロペンタンカルボキサイミド合成中間体の立体異性体および立体異性体混合物
|
|
NZ546058A
(en)
|
2004-01-12 |
2010-09-30 |
Ym Biosciences Australia Pty |
Benzimidazole and other fused ring derivatives as selective janus kinase inhibitors
|
|
GB0402653D0
(en)
|
2004-02-06 |
2004-03-10 |
Cyclacel Ltd |
Compounds
|
|
EP1713806B1
(en)
|
2004-02-14 |
2013-05-08 |
Irm Llc |
Compounds and compositions as protein kinase inhibitors
|
|
US7745625B2
(en)
|
2004-03-15 |
2010-06-29 |
Bristol-Myers Squibb Company |
Prodrugs of piperazine and substituted piperidine antiviral agents
|
|
WO2005107760A1
(en)
|
2004-04-30 |
2005-11-17 |
Irm Llc |
Compounds and compositions as inducers of keratinocyte differentiation
|
|
EP1763514A2
(en)
|
2004-05-18 |
2007-03-21 |
Rigel Pharmaceuticals, Inc. |
Cycloalkyl substituted pyrimidinediamine compounds and their uses
|
|
EP1598343A1
(de)
*
|
2004-05-19 |
2005-11-23 |
Boehringer Ingelheim International GmbH |
2-Arylaminopyrimidine als PLK Inhibitoren
|
|
GB0419161D0
(en)
|
2004-08-27 |
2004-09-29 |
Novartis Ag |
Organic compounds
|
|
US20060047135A1
(en)
|
2004-08-30 |
2006-03-02 |
Chadwick Scott T |
Process for preparing chloromethyl di-tert-butylphosphate
|
|
JP2008511659A
(ja)
|
2004-09-01 |
2008-04-17 |
ライジェル ファーマシューティカルズ， インコーポレイテッド |
２，４−ピリミジンジアミン化合物の合成
|
|
EP1794134A1
(de)
|
2004-09-29 |
2007-06-13 |
Bayer Schering Pharma Aktiengesellschaft |
Substituierte 2-anilinopyrimidine als zellzyklus -kinase oder rezeptortyrosin-kinase inhibitoren, deren herstellung und verwendung als arzneimittel
|
|
CN101031550B
(zh)
|
2004-09-30 |
2015-05-27 |
泰博特克药品有限公司 |
抑制hiv的5-碳环-或杂环取代的嘧啶类
|
|
US7585883B2
(en)
|
2004-10-29 |
2009-09-08 |
Rigel Pharmaceuticals, Inc. |
Substituted pyridines and their uses
|
|
EP1814878B1
(en)
|
2004-11-24 |
2012-01-04 |
Rigel Pharmaceuticals, Inc. |
Spiro-2, 4-pyrimidinediamine compounds and their uses
|
|
US7442716B2
(en)
|
2004-12-17 |
2008-10-28 |
Merck Frosst Canada Ltd. |
2-(phenyl or heterocyclic)-1H-phenantrho[9,10-d]imidazoles as mPGES-1 inhibitors
|
|
AU2005322855B2
(en)
|
2004-12-30 |
2012-09-20 |
Exelixis, Inc. |
Pyrimidine derivatives as kinase modulators and method of use
|
|
DE602006010979D1
(de)
|
2005-01-19 |
2010-01-21 |
Rigel Pharmaceuticals Inc |
Prodrugs aus 2,4-pyrimidindiamin-verbindungen und ihre verwendungen
|
|
EP1883302A4
(en)
|
2005-05-03 |
2009-05-20 |
Rigel Pharmaceuticals Inc |
JAK KINASE HEMMER AND ITS USE
|
|
US20060251285A1
(en)
|
2005-05-05 |
2006-11-09 |
Mrs. Yen-Chen Chan |
[surge-proof damper]
|
|
WO2006133426A2
(en)
*
|
2005-06-08 |
2006-12-14 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
US20070203161A1
(en)
|
2006-02-24 |
2007-08-30 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
EP1896134A2
(en)
|
2005-06-13 |
2008-03-12 |
Rigel Pharmaceuticals, Inc. |
Methods and compositions for treating degenerative bone disorders
|
|
MX2008000574A
(es)
|
2005-07-11 |
2008-03-14 |
Sanofi Aventis |
Nuevos derivados de 2,4-dianilinopirimidinas, la preparacion de los mismos, su uso como medicamentos, composiciones farmaceuticas y, en particular, como inhibidores ikk.
|
|
CA2616512A1
(en)
|
2005-07-28 |
2007-02-08 |
Intervet International B.V. |
Novel benzimidazole (thio) carbamates with antiparasitic activity and the synthesis thereof
|
|
JP4981673B2
(ja)
|
2005-09-13 |
2012-07-25 |
エーザイ・アール・アンド・ディー・マネジメント株式会社 |
安定性が改善されたクロロメチルフォスフェイト誘導体を含む組成物およびその製造方法
|
|
CN103626742B
(zh)
|
2005-11-01 |
2017-04-26 |
塔格根公司 |
激酶的联-芳基间-嘧啶抑制剂
|
|
US7713987B2
(en)
|
2005-12-06 |
2010-05-11 |
Rigel Pharmaceuticals, Inc. |
Pyrimidine-2,4-diamines and their uses
|
|
AU2006327871A1
(en)
|
2005-12-21 |
2007-06-28 |
Pfizer Products Inc. |
Pyrimidine derivatives for the treatment of abnormal cell growth
|
|
TW200736232A
(en)
|
2006-01-26 |
2007-10-01 |
Astrazeneca Ab |
Pyrimidine derivatives
|
|
WO2007085540A1
(en)
|
2006-01-27 |
2007-08-02 |
Glaxo Group Limited |
1h-indaz0l-4-yl-2 , 4-pyrimidinediamine derivatives
|
|
ES2439948T3
(es)
|
2006-02-17 |
2014-01-27 |
Rigel Pharmaceuticals, Inc. |
Compuestos de 2,4-pirimidindiamina para el tratamiento o la prevención de enfermedades autoinmunitarias
|
|
CA2642229C
(en)
|
2006-02-24 |
2015-05-12 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
EP2019675A4
(en)
|
2006-05-02 |
2011-03-02 |
Merck Frosst Canada Ltd |
METHOD FOR THE TREATMENT OR PREVENTION OF NEOPLASIA
|
|
US7776855B2
(en)
|
2006-07-27 |
2010-08-17 |
Janssen Pharmaceutica N.V. |
Antimicrobial oxazolidinone prodrugs
|
|
EP2089369B1
(en)
|
2006-10-19 |
2011-02-02 |
Rigel Pharmaceuticals, Inc. |
2,4 -pyrimidinediamine derivatives as inhibitors of jak kinases for the treatment of autoimmune diseases
|
|
EP2420505A1
(en)
*
|
2006-11-21 |
2012-02-22 |
Rigel Pharmaceuticals, Inc. |
Prodrug salts of 2, 4- pyrimidinediamine compounds and their uses
|
|
CA2670645A1
(en)
|
2006-12-19 |
2008-07-03 |
Genentech, Inc. |
Pyrimidine kinase inhibitors
|
|
AR065015A1
(es)
|
2007-01-26 |
2009-05-13 |
Smithkline Beecham Corp |
Derivados de antranilamida, composiciones farmaceuticas que los contienen, y usos para el tratamiento del cancer
|
|
US7947698B2
(en)
|
2007-03-23 |
2011-05-24 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the JAK pathway
|
|
WO2008118823A2
(en)
|
2007-03-26 |
2008-10-02 |
Rigel Pharmaceuticals, Inc. |
Compositions and methods for inhibition of the jak pathway
|
|
CA2693594A1
(en)
*
|
2007-07-17 |
2009-01-22 |
Rigel Pharmaceuticals, Inc. |
Cyclic amine substituted pyrimidinediamines as pkc inhibitors
|