HK1057543A1 - Pyrazole compounds useful as protein kinase inhibitors - Google Patents

Pyrazole compounds useful as protein kinase inhibitors

Info

Publication number
HK1057543A1
HK1057543A1 HK03108309A HK03108309A HK1057543A1 HK 1057543 A1 HK1057543 A1 HK 1057543A1 HK 03108309 A HK03108309 A HK 03108309A HK 03108309 A HK03108309 A HK 03108309A HK 1057543 A1 HK1057543 A1 HK 1057543A1
Authority
HK
Hong Kong
Prior art keywords
protein kinase
kinase inhibitors
compounds useful
pyrazole compounds
pyrazole
Prior art date
Application number
HK03108309A
Other languages
English (en)
Inventor
Ronald Knegtel
David Bebbington
Hayley Binch
Julian Golec
Sanjay Patel
Jean-Damien Charrier
David Kay
Robert Davies
Pan Li
Marion Wannamaker
Cornelia Forster
Albert C Pierce
Original Assignee
Vertex Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27398347&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1057543(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Vertex Pharma filed Critical Vertex Pharma
Publication of HK1057543A1 publication Critical patent/HK1057543A1/xx

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    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
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    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
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    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
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  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Obesity (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
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  • Urology & Nephrology (AREA)
  • Transplantation (AREA)
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HK03108309A 2000-09-15 2003-11-14 Pyrazole compounds useful as protein kinase inhibitors HK1057543A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US23279500P 2000-09-15 2000-09-15
US25788700P 2000-12-21 2000-12-21
US28694901P 2001-04-27 2001-04-27
PCT/US2001/028740 WO2002022601A1 (fr) 2000-09-15 2001-09-14 Composes pyrazoliques utiles comme inhibiteurs de la proteine kinase

Publications (1)

Publication Number Publication Date
HK1057543A1 true HK1057543A1 (en) 2004-04-08

Family

ID=27398347

Family Applications (8)

Application Number Title Priority Date Filing Date
HK03108309A HK1057543A1 (en) 2000-09-15 2003-11-14 Pyrazole compounds useful as protein kinase inhibitors
HK03108474A HK1057747A1 (en) 2000-09-15 2003-11-20 Pyrazole compounds useful as protein kinase inhbitors
HK03108524A HK1057887A1 (en) 2000-09-15 2003-11-21 Pyrazole compounds useful as protein kinase inhibitors
HK03108588A HK1057748A1 (en) 2000-09-15 2003-11-25 Pyrazole compounds useful as protein kinase inhibitors
HK03108639A HK1057888A1 (en) 2000-09-15 2003-11-26 Pyrazole compounds useful as protein kinase inhibitors
HK03108682A HK1057702A1 (en) 2000-09-15 2003-11-27 Triazole compounds useful as protein kinase inhibitors
HK03108726A HK1057890A1 (en) 2000-09-15 2003-11-28 Pyrazole compounds useful as protein kinase inhibitors.
HK03109140A HK1058356A1 (en) 2000-09-15 2003-12-15 Pyrazole compounds useful as protein kinase inhibitors

Family Applications After (7)

Application Number Title Priority Date Filing Date
HK03108474A HK1057747A1 (en) 2000-09-15 2003-11-20 Pyrazole compounds useful as protein kinase inhbitors
HK03108524A HK1057887A1 (en) 2000-09-15 2003-11-21 Pyrazole compounds useful as protein kinase inhibitors
HK03108588A HK1057748A1 (en) 2000-09-15 2003-11-25 Pyrazole compounds useful as protein kinase inhibitors
HK03108639A HK1057888A1 (en) 2000-09-15 2003-11-26 Pyrazole compounds useful as protein kinase inhibitors
HK03108682A HK1057702A1 (en) 2000-09-15 2003-11-27 Triazole compounds useful as protein kinase inhibitors
HK03108726A HK1057890A1 (en) 2000-09-15 2003-11-28 Pyrazole compounds useful as protein kinase inhibitors.
HK03109140A HK1058356A1 (en) 2000-09-15 2003-12-15 Pyrazole compounds useful as protein kinase inhibitors

Country Status (24)

Country Link
US (7) US6696452B2 (fr)
EP (8) EP1317444B1 (fr)
JP (9) JP4105948B2 (fr)
KR (4) KR100876069B1 (fr)
CN (3) CN1469875A (fr)
AP (1) AP2003002762A0 (fr)
AT (8) ATE294797T1 (fr)
AU (9) AU2001294558A1 (fr)
BR (1) BR0114088A (fr)
CA (8) CA2422367C (fr)
DE (8) DE60120198T2 (fr)
DK (1) DK1318997T3 (fr)
ES (3) ES2266258T3 (fr)
HK (8) HK1057543A1 (fr)
HU (4) HUP0401819A3 (fr)
IL (6) IL154747A0 (fr)
MX (8) MXPA03002289A (fr)
NO (4) NO20031188L (fr)
NZ (4) NZ525014A (fr)
PE (1) PE20020451A1 (fr)
PL (1) PL361676A1 (fr)
PT (2) PT1317448E (fr)
TW (1) TWI303636B (fr)
WO (8) WO2002022607A1 (fr)

Families Citing this family (401)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000516743A (ja) * 1996-09-04 2000-12-12 インタートラスト テクノロージーズ コーポレイション 信用インフラストラクチャストラクチャ支援システム、安全な電子交易、電子商取引、交易プロセス制御及び自動化のための方法及び技術、分散コンピューテーション及び権利管理
US6184226B1 (en) * 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
US6982260B1 (en) 1999-11-22 2006-01-03 Warner-Lambert Company Quinazolines and their use for inhibiting cyclin-dependent kinase enzymes
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