ECSP066461A - Método para activar las poblaciones de célula especificas utilizando conjugados maitansinoides del agente de enlace celular enlazados a través de un enlazador no divisible, dichos conjugados, y métodos para hacer dichos conjugados - Google Patents
Método para activar las poblaciones de célula especificas utilizando conjugados maitansinoides del agente de enlace celular enlazados a través de un enlazador no divisible, dichos conjugados, y métodos para hacer dichos conjugadosInfo
- Publication number
- ECSP066461A ECSP066461A EC2006006461A ECSP066461A ECSP066461A EC SP066461 A ECSP066461 A EC SP066461A EC 2006006461 A EC2006006461 A EC 2006006461A EC SP066461 A ECSP066461 A EC SP066461A EC SP066461 A ECSP066461 A EC SP066461A
- Authority
- EC
- Ecuador
- Prior art keywords
- conjugates
- maitansinoid
- methods
- make
- agent linked
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 4
- 230000003213 activating effect Effects 0.000 title abstract 2
- 239000011230 binding agent Substances 0.000 abstract 3
Classifications
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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- C07K16/32—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against translation products of oncogenes
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Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50990103P | 2003-10-10 | 2003-10-10 | |
| US10/960,602 US8088387B2 (en) | 2003-10-10 | 2004-10-08 | Method of targeting specific cell populations using cell-binding agent maytansinoid conjugates linked via a non-cleavable linker, said conjugates, and methods of making said conjugates |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ECSP066461A true ECSP066461A (es) | 2007-05-30 |
Family
ID=34467962
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| EC2006006461A ECSP066461A (es) | 2003-10-10 | 2006-03-28 | Método para activar las poblaciones de célula especificas utilizando conjugados maitansinoides del agente de enlace celular enlazados a través de un enlazador no divisible, dichos conjugados, y métodos para hacer dichos conjugados |
Country Status (26)
| Country | Link |
|---|---|
| US (10) | US8088387B2 (OSRAM) |
| EP (4) | EP2596803A3 (OSRAM) |
| JP (10) | JP2007520450A (OSRAM) |
| KR (4) | KR20060130552A (OSRAM) |
| CN (3) | CN103223174A (OSRAM) |
| AU (2) | AU2004282491C1 (OSRAM) |
| BE (1) | BE2013C075I2 (OSRAM) |
| BR (1) | BRPI0415448A8 (OSRAM) |
| CA (3) | CA3237922A1 (OSRAM) |
| CY (2) | CY1113984T1 (OSRAM) |
| DK (1) | DK1689846T3 (OSRAM) |
| EA (1) | EA010508B1 (OSRAM) |
| EC (1) | ECSP066461A (OSRAM) |
| ES (1) | ES2404304T3 (OSRAM) |
| FR (1) | FR13C0068I2 (OSRAM) |
| HK (1) | HK1244452A1 (OSRAM) |
| HR (1) | HRP20130412T1 (OSRAM) |
| HU (1) | HUS1300075I1 (OSRAM) |
| IL (4) | IL173625A (OSRAM) |
| LU (1) | LU92336I2 (OSRAM) |
| NO (2) | NO337458B1 (OSRAM) |
| NZ (2) | NZ545195A (OSRAM) |
| PL (1) | PL1689846T3 (OSRAM) |
| PT (1) | PT1689846E (OSRAM) |
| SI (1) | SI1689846T1 (OSRAM) |
| WO (1) | WO2005037992A2 (OSRAM) |
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