DK3280729T3 - Cd20-behandlinger, cd22-behandlinger og kombinationsbehandlinger med en cd19-kimær antigenreceptor (car)-udtrykkende celle - Google Patents

Cd20-behandlinger, cd22-behandlinger og kombinationsbehandlinger med en cd19-kimær antigenreceptor (car)-udtrykkende celle Download PDF

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DK3280729T3
DK3280729T3 DK16719611.2T DK16719611T DK3280729T3 DK 3280729 T3 DK3280729 T3 DK 3280729T3 DK 16719611 T DK16719611 T DK 16719611T DK 3280729 T3 DK3280729 T3 DK 3280729T3
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treatments
car
antigen receptor
chimeric antigen
expressing cell
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DK16719611.2T
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English (en)
Inventor
Hans Bitter
Jennifer Mary Bordeaux
Barbara Brannetti
Jennifer Brogdon
Naveen Kumar Dakappagari
Saar Gill
Steven Highfill
Lu Huang
Carl H June
Ming Lei
Na Li
Elena Orlando
Marco Ruella
Thai Tran
Jimin Zhang
Li Zhou
Andreas Loew
Ju Young Kim
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Novartis Ag
Univ Pennsylvania
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/30—Cellular immunotherapy characterised by the recombinant expression of specific molecules in the cells of the immune system
    • A61K40/31—Chimeric antigen receptors [CAR]
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    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
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DK16719611.2T 2015-04-08 2016-04-08 Cd20-behandlinger, cd22-behandlinger og kombinationsbehandlinger med en cd19-kimær antigenreceptor (car)-udtrykkende celle DK3280729T3 (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US201562144639P 2015-04-08 2015-04-08
US201562144497P 2015-04-08 2015-04-08
US201562144615P 2015-04-08 2015-04-08
US201562207255P 2015-08-19 2015-08-19
US201562263423P 2015-12-04 2015-12-04
PCT/US2016/026655 WO2016164731A2 (en) 2015-04-08 2016-04-08 Cd20 therapies, cd22 therapies, and combination therapies with a cd19 chimeric antigen receptor (car) - expressing cell

Publications (1)

Publication Number Publication Date
DK3280729T3 true DK3280729T3 (da) 2022-07-25

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DK16719611.2T DK3280729T3 (da) 2015-04-08 2016-04-08 Cd20-behandlinger, cd22-behandlinger og kombinationsbehandlinger med en cd19-kimær antigenreceptor (car)-udtrykkende celle

Country Status (23)

Country Link
US (4) US10253086B2 (https=)
EP (3) EP4491715A3 (https=)
JP (4) JP6961490B2 (https=)
KR (1) KR20170134642A (https=)
CN (3) CN108350058B (https=)
AU (2) AU2016245958B2 (https=)
BR (1) BR112017021500A2 (https=)
CA (1) CA2981751A1 (https=)
CO (1) CO2017010190A2 (https=)
DK (1) DK3280729T3 (https=)
ES (2) ES2923894T3 (https=)
HR (1) HRP20220893T1 (https=)
HU (1) HUE059218T2 (https=)
IL (2) IL254817B2 (https=)
LT (1) LT3280729T (https=)
MX (2) MX2017012939A (https=)
PL (1) PL3280729T3 (https=)
PT (1) PT3280729T (https=)
RU (2) RU2752918C2 (https=)
SG (2) SG10201913731UA (https=)
SI (1) SI3280729T1 (https=)
TW (1) TWI746437B (https=)
WO (1) WO2016164731A2 (https=)

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DK2958943T3 (da) 2013-02-20 2019-12-09 Univ Pennsylvania Behandling af cancer ved anvendelse af humaniseret anti-EGFRvIII kimær antigenreceptor
EP2970426B1 (en) 2013-03-15 2019-08-28 Michael C. Milone Targeting cytotoxic cells with chimeric receptors for adoptive immunotherapy
UY35468A (es) 2013-03-16 2014-10-31 Novartis Ag Tratamiento de cáncer utilizando un receptor quimérico de antígeno anti-cd19
ES2918501T3 (es) 2013-12-19 2022-07-18 Novartis Ag Receptores de antígenos quiméricos de mesotelina humana y usos de los mismos
US10287354B2 (en) 2013-12-20 2019-05-14 Novartis Ag Regulatable chimeric antigen receptor
US11028143B2 (en) 2014-01-21 2021-06-08 Novartis Ag Enhanced antigen presenting ability of RNA CAR T cells by co-introduction of costimulatory molecules
SG10201900002QA (en) 2014-01-24 2019-02-27 Dana Farber Cancer Institue Inc Antibody molecules to pd-1 and uses thereof
CN106459990B (zh) 2014-02-07 2021-06-01 麦克马斯特大学 三功能t细胞抗原偶联物及其制备方法和用途
US20150259420A1 (en) 2014-03-14 2015-09-17 Novartis Ag Antibody molecules to lag-3 and uses thereof
AU2015244039B2 (en) 2014-04-07 2021-10-21 Novartis Ag Treatment of cancer using anti-CD19 chimeric antigen receptor
BR112016024072B1 (pt) 2014-04-16 2021-02-09 Juno Therapeutics Gmbh método in vitro de estimular uma população de células
RU2763795C2 (ru) 2014-04-23 2022-01-11 Джуно Терапьютикс, Инк. Способы выделения, культивирования и генетической инженерии популяций клеток иммунной системы для адоптивной терапии
SG10201913765YA (en) 2014-07-21 2020-03-30 Novartis Ag Treatment of cancer using a cd33 chimeric antigen receptor
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CN119925616A (zh) 2025-05-06
SG11201708191XA (en) 2017-11-29
PT3280729T (pt) 2022-08-01
AU2016245958B2 (en) 2021-09-09
IL254817B2 (en) 2023-12-01
AU2016245958A8 (en) 2019-08-08
US10253086B2 (en) 2019-04-09
MX2017012939A (es) 2018-05-22
KR20170134642A (ko) 2017-12-06
TW201639963A (zh) 2016-11-16
US12344657B2 (en) 2025-07-01
RU2752918C2 (ru) 2021-08-11
JP2026053671A (ja) 2026-03-25
RU2021121771A (ru) 2022-01-12
US20190292238A1 (en) 2019-09-26
ES3009008T3 (en) 2025-03-25
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WO2016164731A3 (en) 2016-11-10
EP4056588B1 (en) 2024-09-25

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