|
US4675189A
(en)
*
|
1980-11-18 |
1987-06-23 |
Syntex (U.S.A.) Inc. |
Microencapsulation of water soluble active polypeptides
|
|
US5366734A
(en)
*
|
1981-02-16 |
1994-11-22 |
Zeneca Limited |
Continuous release pharmaceutical compositions
|
|
CH660488A5
(en)
*
|
1982-12-17 |
1987-04-30 |
Sandoz Ag |
(Co)oligomeric hydroxycarboxylic acid derivatives, the preparation thereof, and the use thereof in pharmaceutical compositions
|
|
CA1196864A
(en)
*
|
1983-06-10 |
1985-11-19 |
Mattheus F.A. Goosen |
Controlled release of injectable and implantable insulin compositions
|
|
CH656884A5
(de)
*
|
1983-08-26 |
1986-07-31 |
Sandoz Ag |
Polyolester, deren herstellung und verwendung.
|
|
GB8416234D0
(en)
*
|
1984-06-26 |
1984-08-01 |
Ici Plc |
Biodegradable amphipathic copolymers
|
|
JPS6136321A
(ja)
*
|
1984-07-27 |
1986-02-21 |
Daicel Chem Ind Ltd |
新規なポリマ−およびその樹脂組成物
|
|
US4880635B1
(en)
*
|
1984-08-08 |
1996-07-02 |
Liposome Company |
Dehydrated liposomes
|
|
KR890002631B1
(ko)
*
|
1984-10-04 |
1989-07-21 |
몬산토 캄파니 |
생물학적으로 활성인 소마토트로핀을 지속적으로 유리하는 조성물
|
|
US5411951A
(en)
*
|
1984-10-04 |
1995-05-02 |
Monsanto Company |
Prolonged release of biologically active somatotropin
|
|
US5474980A
(en)
*
|
1984-10-04 |
1995-12-12 |
Monsanto Company |
Prolonged release of biologically active somatotropins
|
|
WO1986002271A1
(en)
*
|
1984-10-19 |
1986-04-24 |
Chiron Corporation |
Promotion of wound healing with human epidermal growth factor prepared from recombinant dna
|
|
US4895724A
(en)
*
|
1985-06-07 |
1990-01-23 |
Pfizer Inc. |
Chitosan compositions for controlled and prolonged release of macromolecules
|
|
US5036045A
(en)
*
|
1985-09-12 |
1991-07-30 |
The University Of Virginia Alumni Patents Foundation |
Method for increasing growth hormone secretion
|
|
US5102872A
(en)
*
|
1985-09-20 |
1992-04-07 |
Cetus Corporation |
Controlled-release formulations of interleukin-2
|
|
US4959217A
(en)
*
|
1986-05-22 |
1990-09-25 |
Syntex (U.S.A.) Inc. |
Delayed/sustained release of macromolecules
|
|
US4832686A
(en)
*
|
1986-06-24 |
1989-05-23 |
Anderson Mark E |
Method for administering interleukin-2
|
|
US4801457A
(en)
*
|
1986-08-01 |
1989-01-31 |
Sandoz Pharm. Corp. |
Polyacetal hydrogels formed from divinyl ethers and polyols
|
|
US4882168A
(en)
*
|
1986-09-05 |
1989-11-21 |
American Cyanamid Company |
Polyesters containing alkylene oxide blocks as drug delivery systems
|
|
JPH0725689B2
(ja)
*
|
1986-10-07 |
1995-03-22 |
中外製薬株式会社 |
顆粒球コロニ−刺激因子を含有する徐放性製剤
|
|
US5075109A
(en)
*
|
1986-10-24 |
1991-12-24 |
Southern Research Institute |
Method of potentiating an immune response
|
|
US5811128A
(en)
*
|
1986-10-24 |
1998-09-22 |
Southern Research Institute |
Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
|
|
US5183746A
(en)
*
|
1986-10-27 |
1993-02-02 |
Schering Aktiengesellschaft |
Formulation processes for pharmaceutical compositions of recombinant β-
|
|
US5037644A
(en)
*
|
1986-10-27 |
1991-08-06 |
Cetus Corporation |
Pharmaceutical compositions of recombinant interleukin-2 and formulation processes
|
|
US5688519A
(en)
*
|
1987-04-06 |
1997-11-18 |
Leonard; Robert J. |
Flash-flow fused medicinal implants
|
|
US5000886A
(en)
*
|
1987-05-26 |
1991-03-19 |
American Cyanamid Company |
Silicone-hardened pharmaceutical microcapsules and process of making the same
|
|
US5938654A
(en)
*
|
1987-06-25 |
1999-08-17 |
Alza Corporation |
Osmotic device for delayed delivery of agent
|
|
US5236689A
(en)
*
|
1987-06-25 |
1993-08-17 |
Alza Corporation |
Multi-unit delivery system
|
|
US5391381A
(en)
*
|
1987-06-25 |
1995-02-21 |
Alza Corporation |
Dispenser capable of delivering plurality of drug units
|
|
US5340590A
(en)
*
|
1987-06-25 |
1994-08-23 |
Alza Corporation |
Delivery system with bilayer osmotic engine
|
|
US4992418A
(en)
*
|
1987-07-17 |
1991-02-12 |
Mount Sinai School Of Medicine |
Superactive human insulin analogue-[10-Aspartic Acid-B]Human Insulin
|
|
GB2209937B
(en)
*
|
1987-09-21 |
1991-07-03 |
Depiopharm S A |
Water insoluble polypeptides
|
|
US5017560A
(en)
*
|
1987-11-06 |
1991-05-21 |
Pitman-Moore, Inc. |
Poultry growth promotion
|
|
US5004605A
(en)
*
|
1987-12-10 |
1991-04-02 |
Cetus Corporation |
Low pH pharmaceutical compositions of recombinant β-interferon
|
|
JPH01163135A
(ja)
*
|
1987-12-18 |
1989-06-27 |
Taki Chem Co Ltd |
徐放性基剤の製造方法
|
|
GB8801863D0
(en)
*
|
1988-01-28 |
1988-02-24 |
Fulmer Yarsley Ltd |
Pharmaceutical formulations with controlled drug release
|
|
US5137669A
(en)
*
|
1988-03-02 |
1992-08-11 |
Endocon, Inc. |
Manufacture of partially fused peptide pellet
|
|
US4996060A
(en)
*
|
1988-03-25 |
1991-02-26 |
Alza Corporation |
Device comprising liner for protecting fluid sensitive medicament
|
|
US4959218A
(en)
*
|
1988-03-25 |
1990-09-25 |
Alza Corporation |
Method for delivering somatotropin to an animal
|
|
US5078997A
(en)
*
|
1988-07-13 |
1992-01-07 |
Cetus Corporation |
Pharmaceutical composition for interleukin-2 containing physiologically compatible stabilizers
|
|
US5444113A
(en)
*
|
1988-08-08 |
1995-08-22 |
Ecopol, Llc |
End use applications of biodegradable polymers
|
|
US5216050A
(en)
*
|
1988-08-08 |
1993-06-01 |
Biopak Technology, Ltd. |
Blends of polyactic acid
|
|
US5252642A
(en)
*
|
1989-03-01 |
1993-10-12 |
Biopak Technology, Ltd. |
Degradable impact modified polyactic acid
|
|
US4925677A
(en)
*
|
1988-08-31 |
1990-05-15 |
Theratech, Inc. |
Biodegradable hydrogel matrices for the controlled release of pharmacologically active agents
|
|
JPH064540B2
(ja)
*
|
1988-09-14 |
1994-01-19 |
多木化学株式会社 |
医用組成物
|
|
US5037420A
(en)
*
|
1988-12-13 |
1991-08-06 |
Alza Corporation |
Delivery system comprising two sections for delivering somatotropin
|
|
US5059423A
(en)
*
|
1988-12-13 |
1991-10-22 |
Alza Corporation |
Delivery system comprising biocompatible beneficial agent formulation
|
|
US5135523A
(en)
*
|
1988-12-13 |
1992-08-04 |
Alza Corporation |
Delivery system for administering agent to ruminants and swine
|
|
US5034229A
(en)
*
|
1988-12-13 |
1991-07-23 |
Alza Corporation |
Dispenser for increasing feed conversion of hog
|
|
US5728088A
(en)
*
|
1988-12-13 |
1998-03-17 |
Alza Corporation |
Osmotic system for delivery of fluid-sensitive somatotropins to bovine animals
|
|
US5057318A
(en)
*
|
1988-12-13 |
1991-10-15 |
Alza Corporation |
Delivery system for beneficial agent over a broad range of rates
|
|
US5174999A
(en)
*
|
1988-12-13 |
1992-12-29 |
Alza Corporation |
Delivery system comprising fluid ingress and drug egress
|
|
US5110596A
(en)
*
|
1988-12-13 |
1992-05-05 |
Alza Corporation |
Delivery system comprising means for delivering agent to livestock
|
|
US4990336A
(en)
*
|
1989-02-08 |
1991-02-05 |
Biosearch, Inc. |
Sustained release dosage form
|
|
EP0461108B1
(en)
*
|
1989-03-09 |
1994-06-01 |
Endocon, Inc. |
Partially fused peptide pellet
|
|
US5538739A
(en)
*
|
1989-07-07 |
1996-07-23 |
Sandoz Ltd. |
Sustained release formulations of water soluble peptides
|
|
PH30995A
(en)
*
|
1989-07-07 |
1997-12-23 |
Novartis Inc |
Sustained release formulations of water soluble peptides.
|
|
HU221294B1
(en)
*
|
1989-07-07 |
2002-09-28 |
Novartis Ag |
Process for producing retarde compositions containing the active ingredient in a polymeric carrier
|
|
US5324519A
(en)
*
|
1989-07-24 |
1994-06-28 |
Atrix Laboratories, Inc. |
Biodegradable polymer composition
|
|
US5487897A
(en)
*
|
1989-07-24 |
1996-01-30 |
Atrix Laboratories, Inc. |
Biodegradable implant precursor
|
|
US5225205A
(en)
*
|
1989-07-28 |
1993-07-06 |
Debiopharm S.A. |
Pharmaceutical composition in the form of microparticles
|
|
EP0423484B1
(de)
*
|
1989-10-16 |
1993-11-03 |
PCD-Polymere Gesellschaft m.b.H. |
Pressling mit retardierter Wirkstofffreisetzung
|
|
DE3935736A1
(de)
*
|
1989-10-27 |
1991-05-02 |
Chemie Linz Deutschland |
Pressling mit retardierter wirkstofffreisetzung
|
|
US5126147A
(en)
*
|
1990-02-08 |
1992-06-30 |
Biosearch, Inc. |
Sustained release dosage form
|
|
US6552170B1
(en)
|
1990-04-06 |
2003-04-22 |
Amgen Inc. |
PEGylation reagents and compounds formed therewith
|
|
US5091185A
(en)
*
|
1990-06-20 |
1992-02-25 |
Monsanto Company |
Coated veterinary implants
|
|
US5360892A
(en)
*
|
1990-06-26 |
1994-11-01 |
Arch Development Corporation |
Water and UV degradable lactic acid polymers
|
|
US5234692A
(en)
*
|
1990-07-11 |
1993-08-10 |
Alza Corporation |
Delivery device with a protective sleeve
|
|
US5234694A
(en)
*
|
1990-07-11 |
1993-08-10 |
Alza Corporation |
Method for increasing feed efficiency in animals
|
|
US5234693A
(en)
*
|
1990-07-11 |
1993-08-10 |
Alza Corporation |
Delivery device with a protective sleeve
|
|
US5180591A
(en)
*
|
1990-07-11 |
1993-01-19 |
Alza Corporation |
Delivery device with a protective sleeve
|
|
US5238687A
(en)
*
|
1990-07-11 |
1993-08-24 |
Alza Corporation |
Delivery device with a protective sleeve
|
|
IE912365A1
(en)
*
|
1990-07-23 |
1992-01-29 |
Zeneca Ltd |
Continuous release pharmaceutical compositions
|
|
US6353030B1
(en)
*
|
1990-08-01 |
2002-03-05 |
Novartis Ag |
Relating to organic compounds
|
|
US5410016A
(en)
*
|
1990-10-15 |
1995-04-25 |
Board Of Regents, The University Of Texas System |
Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
|
|
US5626863A
(en)
*
|
1992-02-28 |
1997-05-06 |
Board Of Regents, The University Of Texas System |
Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
|
|
US5462990A
(en)
*
|
1990-10-15 |
1995-10-31 |
Board Of Regents, The University Of Texas System |
Multifunctional organic polymers
|
|
IT1243390B
(it)
*
|
1990-11-22 |
1994-06-10 |
Vectorpharma Int |
Composizioni farmaceutiche in forma di particelle atte al rilascio controllato di sostanze farmacologicamente attive e procedimento per la loro preparazione.
|
|
US5443459A
(en)
*
|
1991-01-30 |
1995-08-22 |
Alza Corporation |
Osmotic device for delayed delivery of agent
|
|
US5861166A
(en)
*
|
1991-03-12 |
1999-01-19 |
Alza Corporation |
Delivery device providing beneficial agent stability
|
|
HUT67238A
(en)
*
|
1991-05-14 |
1995-03-28 |
Endocon Inc |
Controlled realising implant preparations
|
|
US5137727A
(en)
*
|
1991-06-12 |
1992-08-11 |
Alza Corporation |
Delivery device providing beneficial agent stability
|
|
FR2678168B1
(fr)
|
1991-06-28 |
1993-09-03 |
Rhone Poulenc Rorer Sa |
Nanoparticules ayant un temps de capture par le dysteme reticulo endothelial allonge.
|
|
EP0596123A4
(en)
*
|
1991-10-31 |
1995-03-29 |
Kobe Steel Ltd |
BIODEGRADABLE PLASTIC MATERIAL.
|
|
NZ249770A
(en)
|
1992-02-28 |
1996-09-25 |
Univ Texas |
Biodegradable, polymerisable, substantially water soluble macromer comprising at least one water soluble region, at least one degradable region and at least two free radical polymerisable regions separated by at least one degradable region
|
|
US5573934A
(en)
*
|
1992-04-20 |
1996-11-12 |
Board Of Regents, The University Of Texas System |
Gels for encapsulation of biological materials
|
|
US5352515A
(en)
*
|
1992-03-02 |
1994-10-04 |
American Cyanamid Company |
Coating for tissue drag reduction
|
|
US5518730A
(en)
|
1992-06-03 |
1996-05-21 |
Fuisz Technologies Ltd. |
Biodegradable controlled release flash flow melt-spun delivery system
|
|
US5981719A
(en)
*
|
1993-03-09 |
1999-11-09 |
Epic Therapeutics, Inc. |
Macromolecular microparticles and methods of production and use
|
|
US6090925A
(en)
*
|
1993-03-09 |
2000-07-18 |
Epic Therapeutics, Inc. |
Macromolecular microparticles and methods of production and use
|
|
KR960015447B1
(ko)
*
|
1993-03-16 |
1996-11-14 |
주식회사 삼양사 |
의료용 생분해성 고분자
|
|
US6284727B1
(en)
|
1993-04-07 |
2001-09-04 |
Scios, Inc. |
Prolonged delivery of peptides
|
|
NZ250844A
(en)
*
|
1993-04-07 |
1996-03-26 |
Pfizer |
Treatment of non-insulin dependant diabetes with peptides; composition
|
|
US6191105B1
(en)
*
|
1993-05-10 |
2001-02-20 |
Protein Delivery, Inc. |
Hydrophilic and lipophilic balanced microemulsion formulations of free-form and/or conjugation-stabilized therapeutic agents such as insulin
|
|
US5359030A
(en)
*
|
1993-05-10 |
1994-10-25 |
Protein Delivery, Inc. |
Conjugation-stabilized polypeptide compositions, therapeutic delivery and diagnostic formulations comprising same, and method of making and using the same
|
|
US20050181976A1
(en)
*
|
1993-05-10 |
2005-08-18 |
Ekwuribe Nnochiri N. |
Amphiphilic oligomers
|
|
US5522841A
(en)
*
|
1993-05-27 |
1996-06-04 |
United States Surgical Corporation |
Absorbable block copolymers and surgical articles fabricated therefrom
|
|
JP3220331B2
(ja)
*
|
1993-07-20 |
2001-10-22 |
エチコン・インコーポレーテツド |
非経口投与用の吸収性液体コポリマー類
|
|
US5565215A
(en)
*
|
1993-07-23 |
1996-10-15 |
Massachusettes Institute Of Technology |
Biodegradable injectable particles for imaging
|
|
US5543158A
(en)
*
|
1993-07-23 |
1996-08-06 |
Massachusetts Institute Of Technology |
Biodegradable injectable nanoparticles
|
|
WO1995003356A1
(en)
*
|
1993-07-23 |
1995-02-02 |
Massachusetts Institute Of Technology |
Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
|
|
US5876438A
(en)
*
|
1993-08-02 |
1999-03-02 |
Houston Biotechnology Incorporated |
Polymeric device for the delivery of immunotoxins for the prevention of secondary cataract
|
|
US5563238A
(en)
*
|
1993-08-05 |
1996-10-08 |
Arch Development Corporation |
Water and UV degradable lactic acid polymers
|
|
KR0148704B1
(ko)
*
|
1994-01-10 |
1998-08-17 |
김상응 |
생체분해성 약물전달용 고분자
|
|
US5417982A
(en)
*
|
1994-02-17 |
1995-05-23 |
Modi; Pankaj |
Controlled release of drugs or hormones in biodegradable polymer microspheres
|
|
US5569468A
(en)
*
|
1994-02-17 |
1996-10-29 |
Modi; Pankaj |
Vaccine delivery system for immunization, using biodegradable polymer microspheres
|
|
US5527271A
(en)
*
|
1994-03-30 |
1996-06-18 |
Bristol-Myers Squibb Co. |
Thermoplastic hydrogel impregnated composite material
|
|
KR0141431B1
(ko)
*
|
1994-05-17 |
1998-07-01 |
김상웅 |
생분해성 하이드로겔 고분자
|
|
GB9412273D0
(en)
*
|
1994-06-18 |
1994-08-10 |
Univ Nottingham |
Administration means
|
|
US6007845A
(en)
*
|
1994-07-22 |
1999-12-28 |
Massachusetts Institute Of Technology |
Nanoparticles and microparticles of non-linear hydrophilic-hydrophobic multiblock copolymers
|
|
US6063116A
(en)
*
|
1994-10-26 |
2000-05-16 |
Medarex, Inc. |
Modulation of cell proliferation and wound healing
|
|
US5714573A
(en)
*
|
1995-01-19 |
1998-02-03 |
Cargill, Incorporated |
Impact modified melt-stable lactide polymer compositions and processes for manufacture thereof
|
|
US5618850A
(en)
*
|
1995-03-09 |
1997-04-08 |
Focal, Inc. |
Hydroxy-acid cosmetics
|
|
US5955159A
(en)
*
|
1995-03-15 |
1999-09-21 |
Acushnet Company |
Conforming shoe construction using gels and method of making the same
|
|
US5985383A
(en)
*
|
1995-03-15 |
1999-11-16 |
Acushnet Company |
Conforming shoe construction and gel compositions therefor
|
|
US5939157A
(en)
*
|
1995-10-30 |
1999-08-17 |
Acushnet Company |
Conforming shoe construction using gels and method of making the same
|
|
CA2215317C
(en)
|
1995-03-24 |
2002-07-23 |
Focal, Inc. |
Reduction of adhesions using controlled delivery of active oxygen inhibitors
|
|
US5612052A
(en)
*
|
1995-04-13 |
1997-03-18 |
Poly-Med, Inc. |
Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
|
|
US6413539B1
(en)
|
1996-10-31 |
2002-07-02 |
Poly-Med, Inc. |
Hydrogel-forming, self-solvating absorbable polyester copolymers, and methods for use thereof
|
|
US5690952A
(en)
*
|
1995-06-07 |
1997-11-25 |
Judy A. Magruder et al. |
Implantable system for delivery of fluid-sensitive agents to animals
|
|
US5904935A
(en)
*
|
1995-06-07 |
1999-05-18 |
Alza Corporation |
Peptide/protein suspending formulations
|
|
CA2197087C
(en)
*
|
1995-06-12 |
2006-02-07 |
Stephen T. Wellinghoff |
Sustained release, transparent biocidal compositions
|
|
EP0842209B1
(en)
|
1995-07-28 |
2006-10-11 |
Genzyme Corporation |
Multiblock biodegradable hydrogels for use as controlled release agents for drugs and tissue treatment agents
|
|
KR0180334B1
(ko)
*
|
1995-09-21 |
1999-03-20 |
김윤 |
블럭 공중합체 미셀을 이용한 약물전달체 및 이에 약물을 봉입하는 방법
|
|
US5773019A
(en)
*
|
1995-09-27 |
1998-06-30 |
The University Of Kentucky Research Foundation |
Implantable controlled release device to deliver drugs directly to an internal portion of the body
|
|
US5702717A
(en)
*
|
1995-10-25 |
1997-12-30 |
Macromed, Inc. |
Thermosensitive biodegradable polymers based on poly(ether-ester)block copolymers
|
|
US5665428A
(en)
*
|
1995-10-25 |
1997-09-09 |
Macromed, Inc. |
Preparation of peptide containing biodegradable microspheres by melt process
|
|
US5766704A
(en)
*
|
1995-10-27 |
1998-06-16 |
Acushnet Company |
Conforming shoe construction and gel compositions therefor
|
|
FR2741628B1
(fr)
|
1995-11-29 |
1998-02-06 |
Centre Nat Rech Scient |
Nouveaux hydrogels a base de copolymeres trisequences et leur application notamment a la liberation progressive de principes actifs
|
|
US5611344A
(en)
*
|
1996-03-05 |
1997-03-18 |
Acusphere, Inc. |
Microencapsulated fluorinated gases for use as imaging agents
|
|
ES2248847T3
(es)
*
|
1996-05-24 |
2006-03-16 |
Angiotech Pharmaceuticals, Inc. |
Composiciones y metodos para tratar o prevenir enfermedades de las vias de conduccion del cuerpo.
|
|
TW555765B
(en)
|
1996-07-09 |
2003-10-01 |
Amgen Inc |
Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
|
|
US5756651A
(en)
*
|
1996-07-17 |
1998-05-26 |
Chronopol, Inc. |
Impact modified polylactide
|
|
US5837221A
(en)
*
|
1996-07-29 |
1998-11-17 |
Acusphere, Inc. |
Polymer-lipid microencapsulated gases for use as imaging agents
|
|
ZA978537B
(en)
|
1996-09-23 |
1998-05-12 |
Focal Inc |
Polymerizable biodegradable polymers including carbonate or dioxanone linkages.
|
|
US6191236B1
(en)
|
1996-10-11 |
2001-02-20 |
United States Surgical Corporation |
Bioabsorbable suture and method of its manufacture
|
|
US20070185032A1
(en)
*
|
1996-12-11 |
2007-08-09 |
Praecis Pharmaceuticals, Inc. |
Pharmaceutical formulations for sustained drug delivery
|
|
US5968895A
(en)
*
|
1996-12-11 |
1999-10-19 |
Praecis Pharmaceuticals, Inc. |
Pharmaceutical formulations for sustained drug delivery
|
|
ZA9711385B
(en)
*
|
1996-12-20 |
1999-06-18 |
Takeda Chemical Industries Ltd |
Method of producing a sustained-release preparation
|
|
WO1998029506A1
(en)
|
1996-12-31 |
1998-07-09 |
Kimberly-Clark Worldwide, Inc. |
Water-responsive polymer compositions and method of making the same
|
|
US6402520B1
(en)
*
|
1997-04-30 |
2002-06-11 |
Unique Logic And Technology, Inc. |
Electroencephalograph based biofeedback system for improving learning skills
|
|
EP0986402A2
(en)
|
1997-06-06 |
2000-03-22 |
Battelle Memorial Institute |
Reversible geling co-polymer and method of making
|
|
US5945480A
(en)
*
|
1997-07-31 |
1999-08-31 |
Kimberly-Clark Worldwide, Inc. |
Water-responsive, biodegradable fibers comprising polylactide modified polylactide and polyvinyl alcohol, and method for making the fibers
|
|
US5952433A
(en)
*
|
1997-07-31 |
1999-09-14 |
Kimberly-Clark Worldwide, Inc. |
Modified polyactide compositions and a reactive-extrusion process to make the same
|
|
US6552162B1
(en)
|
1997-07-31 |
2003-04-22 |
Kimberly-Clark Worldwide, Inc. |
Water-responsive, biodegradable compositions and films and articles comprising a blend of polylactide and polyvinyl alcohol and methods for making the same
|
|
US6075118A
(en)
*
|
1997-07-31 |
2000-06-13 |
Kimberly-Clark Worldwide, Inc. |
Water-responsive, biodegradable film compositions comprising polylactide and polyvinyl alcohol, and a method for making the films
|
|
EP1024790A4
(en)
*
|
1997-08-08 |
2000-10-25 |
Univ Utah Res Found |
INJECTABLE BIODEGRADABLE BLOCK COPOLYMER GELS FOR USE IN DRUG ADMINISTRATION
|
|
US5852117A
(en)
*
|
1997-08-26 |
1998-12-22 |
National Starch And Chemical Investment Holding Corporation |
Process for making lactide graft copolymers
|
|
US6007565A
(en)
*
|
1997-09-05 |
1999-12-28 |
United States Surgical |
Absorbable block copolymers and surgical articles fabricated therefrom
|
|
US6201072B1
(en)
|
1997-10-03 |
2001-03-13 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
|
US6004573A
(en)
*
|
1997-10-03 |
1999-12-21 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly(lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
|
US6117949A
(en)
*
|
1998-10-01 |
2000-09-12 |
Macromed, Inc. |
Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties
|
|
US20020164374A1
(en)
*
|
1997-10-29 |
2002-11-07 |
John Jackson |
Polymeric systems for drug delivery and uses thereof
|
|
US6277927B1
(en)
|
1997-11-26 |
2001-08-21 |
United States Surgical Corporation |
Absorbable block copolymers and surgical articles fabricated therefrom
|
|
US6613358B2
(en)
|
1998-03-18 |
2003-09-02 |
Theodore W. Randolph |
Sustained-release composition including amorphous polymer
|
|
EP1073419A4
(en)
*
|
1998-03-18 |
2009-03-25 |
Univ Technology Corp |
COMPOSITION, CONTAINING AMORPHOUS POLYMER, FOR DELAYED RELEASE.
|
|
ES2359973T3
(es)
*
|
1998-03-19 |
2011-05-30 |
MERCK SHARP & DOHME CORP. |
Composiciones poliméricas líquidas para la liberación controlada de sustancias bioactivas.
|
|
CN1263435C
(zh)
*
|
1998-03-19 |
2006-07-12 |
麦克公司 |
控制释放生物活性物质的液态聚合物组合物
|
|
DE19812688A1
(de)
*
|
1998-03-23 |
1999-09-30 |
Basf Ag |
Verfahren zur Herstellung von festen Dosierungsformen
|
|
US6841617B2
(en)
*
|
2000-09-28 |
2005-01-11 |
Battelle Memorial Institute |
Thermogelling biodegradable aqueous polymer solution
|
|
US20040228794A1
(en)
*
|
1998-04-10 |
2004-11-18 |
Battelle Memorial Institute |
Therapeutic agent carrier compositions
|
|
US7087244B2
(en)
*
|
2000-09-28 |
2006-08-08 |
Battelle Memorial Institute |
Thermogelling oligopeptide polymers
|
|
US7128927B1
(en)
|
1998-04-14 |
2006-10-31 |
Qlt Usa, Inc. |
Emulsions for in-situ delivery systems
|
|
US6350518B1
(en)
|
1998-06-01 |
2002-02-26 |
Kimberly-Clark Worldwide, Inc. |
Methods of making blend compositions of an unmodified poly vinyl alcohol and a thermoplastic elastomer
|
|
KR100501817B1
(ko)
*
|
1998-07-21 |
2005-07-20 |
몬산토 테크놀로지 엘엘씨 |
음이온 폴리머성 응집제들을 사용한 단백질 침전물 현탁액의 청징화 방법
|
|
US20050147690A1
(en)
*
|
1998-09-25 |
2005-07-07 |
Masters David B. |
Biocompatible protein particles, particle devices and methods thereof
|
|
US7662409B2
(en)
*
|
1998-09-25 |
2010-02-16 |
Gel-Del Technologies, Inc. |
Protein matrix materials, devices and methods of making and using thereof
|
|
US6660843B1
(en)
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
|
US6143314A
(en)
*
|
1998-10-28 |
2000-11-07 |
Atrix Laboratories, Inc. |
Controlled release liquid delivery compositions with low initial drug burst
|
|
WO2002085337A1
(en)
*
|
2001-04-20 |
2002-10-31 |
The University Of British Columbia |
Micellar drug delivery systems for hydrophobic drugs
|
|
US6451346B1
(en)
*
|
1998-12-23 |
2002-09-17 |
Amgen Inc |
Biodegradable pH/thermosensitive hydrogels for sustained delivery of biologically active agents
|
|
JP4865947B2
(ja)
*
|
1999-02-19 |
2012-02-01 |
ウニフェルシテイト ユトレヒト |
ステレオコンプレックスヒドロゲル
|
|
JP4548623B2
(ja)
|
1999-02-24 |
2010-09-22 |
多木化学株式会社 |
生体材料
|
|
JP2002539172A
(ja)
|
1999-03-17 |
2002-11-19 |
ノバルティス アクチエンゲゼルシャフト |
Tgf−ベータを含む医薬組成物
|
|
US6217630B1
(en)
|
1999-05-03 |
2001-04-17 |
Cargill, Incorporated |
Conditioned fertilizer product, method for conditioning fertilizer, and method for using conditioned fertilizer product
|
|
JP4524923B2
(ja)
*
|
1999-05-19 |
2010-08-18 |
日油株式会社 |
ポリマー、生体内分解性材料および用途
|
|
US7169889B1
(en)
|
1999-06-19 |
2007-01-30 |
Biocon Limited |
Insulin prodrugs hydrolyzable in vivo to yield peglylated insulin
|
|
US6521431B1
(en)
|
1999-06-22 |
2003-02-18 |
Access Pharmaceuticals, Inc. |
Biodegradable cross-linkers having a polyacid connected to reactive groups for cross-linking polymer filaments
|
|
US7279176B1
(en)
|
1999-09-02 |
2007-10-09 |
Rice University |
Nitric oxide-producing hydrogel materials
|
|
US7052711B2
(en)
*
|
1999-09-02 |
2006-05-30 |
Rice University |
Nitric oxide-producing hydrogel materials
|
|
US8226598B2
(en)
*
|
1999-09-24 |
2012-07-24 |
Tolmar Therapeutics, Inc. |
Coupling syringe system and methods for obtaining a mixed composition
|
|
CA2398466A1
(en)
*
|
2000-01-27 |
2001-08-02 |
Medimmune, Inc. |
Ultra high affinity neutralizing antibodies
|
|
US7229619B1
(en)
|
2000-11-28 |
2007-06-12 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
WO2001064274A2
(en)
*
|
2000-03-01 |
2001-09-07 |
Glaxo Group Limited |
Metered dose inhaler
|
|
AU4002001A
(en)
*
|
2000-03-01 |
2001-09-12 |
Med Immune Inc |
High potency recombinant antibodies and method for producing them
|
|
US7193007B2
(en)
*
|
2000-03-15 |
2007-03-20 |
Yu-Ling Cheng |
Environment responsive gelling copolymer
|
|
US7018645B1
(en)
|
2000-04-27 |
2006-03-28 |
Macromed, Inc. |
Mixtures of various triblock polyester polyethylene glycol copolymers having improved gel properties
|
|
US20040023987A1
(en)
*
|
2000-06-14 |
2004-02-05 |
Yoshio Hata |
Sustained release compositions
|
|
AU7627601A
(en)
*
|
2000-06-29 |
2002-01-08 |
Rudiger Marcus Flaig |
Drug-delivery systems
|
|
US6338859B1
(en)
*
|
2000-06-29 |
2002-01-15 |
Labopharm Inc. |
Polymeric micelle compositions
|
|
KR100451910B1
(ko)
*
|
2000-10-05 |
2004-10-08 |
주식회사 바이오폴리테크 |
수용성 생체분해성 고분자 겔 및 그의 제조방법
|
|
DE10055742B4
(de)
*
|
2000-11-10 |
2006-05-11 |
Schwarz Pharma Ag |
Neue Polyester, Verfahren zu ihrer Herstellung und aus den Polyestern hergestellte Depot-Arzneiformen
|
|
US7179900B2
(en)
|
2000-11-28 |
2007-02-20 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
AU1994402A
(en)
|
2000-11-28 |
2002-06-11 |
Mediummune Inc |
Methods of administering/dosing anti-rsv antibodies for prophylaxis and treatment
|
|
US6855493B2
(en)
|
2000-11-28 |
2005-02-15 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
|
US6818216B2
(en)
|
2000-11-28 |
2004-11-16 |
Medimmune, Inc. |
Anti-RSV antibodies
|
|
JP4336498B2
(ja)
|
2000-12-12 |
2009-09-30 |
メディミューン,エルエルシー |
延長した半減期を有する分子ならびにその組成物および用途
|
|
ES2390425T3
(es)
|
2000-12-22 |
2012-11-12 |
MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. |
Uso de moléculas de orientación repulsivas (RGM) y sus moduladores
|
|
DE60117857D1
(de)
|
2000-12-27 |
2006-05-04 |
Genzyme Corp |
Kontrollierte freisetzung von anti-arrhythmica aus einem biodegradierbaren hydrogel für die lokale anwendung am herzen
|
|
US7060675B2
(en)
|
2001-02-15 |
2006-06-13 |
Nobex Corporation |
Methods of treating diabetes mellitus
|
|
WO2002098370A2
(en)
*
|
2001-03-02 |
2002-12-12 |
Medimmune, Inc. |
Methods of administering/dosing cd2 antagonists for the prevention and treatment of autoimmune disorders or inflammatory disorders
|
|
DE10111767B4
(de)
*
|
2001-03-12 |
2005-03-24 |
Schwarz Pharma Ag |
Verfahren zur Herstellung von Polyestern aus Hydroxycarbonsäuren und Polyolen durch Polykondensation
|
|
EP1418945A2
(en)
*
|
2001-03-13 |
2004-05-19 |
Angiotech Pharmaceuticals, Inc. |
Micellar drug delivery vehicles and uses thereof
|
|
US20030157170A1
(en)
*
|
2001-03-13 |
2003-08-21 |
Richard Liggins |
Micellar drug delivery vehicles and precursors thereto and uses thereof
|
|
US20040185101A1
(en)
*
|
2001-03-27 |
2004-09-23 |
Macromed, Incorporated. |
Biodegradable triblock copolymers as solubilizing agents for drugs and method of use thereof
|
|
US6835802B2
(en)
|
2001-06-04 |
2004-12-28 |
Nobex Corporation |
Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
|
|
US7713932B2
(en)
|
2001-06-04 |
2010-05-11 |
Biocon Limited |
Calcitonin drug-oligomer conjugates, and uses thereof
|
|
US6939564B2
(en)
*
|
2001-06-08 |
2005-09-06 |
Labopharm, Inc. |
Water-soluble stabilized self-assembled polyelectrolytes
|
|
CA2451187C
(en)
|
2001-06-22 |
2012-08-14 |
Southern Biosystems, Inc. |
Zero-order prolonged release coaxial implants
|
|
WO2003006081A1
(fr)
*
|
2001-07-13 |
2003-01-23 |
Mebiol Inc. |
Materiau de regeneration de tissus/organes et procede associe
|
|
US7309498B2
(en)
*
|
2001-10-10 |
2007-12-18 |
Belenkaya Bronislava G |
Biodegradable absorbents and methods of preparation
|
|
AU2002343681B2
(en)
*
|
2001-11-12 |
2006-07-06 |
Alkermes Controlled Therapeutics, Inc. |
Biocompatible polymer blends and uses thereof
|
|
US7763663B2
(en)
*
|
2001-12-19 |
2010-07-27 |
University Of Massachusetts |
Polysaccharide-containing block copolymer particles and uses thereof
|
|
DE60327752D1
(de)
|
2002-03-14 |
2009-07-09 |
Medrx Co Ltd |
Topisches medikament für wunden
|
|
US7018655B2
(en)
*
|
2002-03-18 |
2006-03-28 |
Labopharm, Inc. |
Amphiphilic diblock, triblock and star-block copolymers and their pharmaceutical compositions
|
|
US8623393B2
(en)
*
|
2002-04-29 |
2014-01-07 |
Gel-Del Technologies, Inc. |
Biomatrix structural containment and fixation systems and methods of use thereof
|
|
US7649023B2
(en)
|
2002-06-11 |
2010-01-19 |
Novartis Ag |
Biodegradable block copolymeric compositions for drug delivery
|
|
US20030228366A1
(en)
*
|
2002-06-11 |
2003-12-11 |
Chung Shih |
Reconstitutable compositions of biodegradable block copolymers
|
|
US7425618B2
(en)
*
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
|
WO2004010935A2
(en)
*
|
2002-07-25 |
2004-02-05 |
Medimmune, Inc. |
Methods of treating and preventing rsv, hmpv, and piv using anti-rsv, anti-hmpv, and anti-piv antibodies
|
|
WO2004016750A2
(en)
|
2002-08-14 |
2004-02-26 |
Macrogenics, Inc. |
FcϜRIIB-SPECIFIC ANTIBODIES AND METHODS OF USE THEREOF
|
|
CA2497628A1
(en)
*
|
2002-09-05 |
2004-03-18 |
Medimmune, Inc. |
Methods of preventing or treating cell malignancies by administering cd2 antagonists
|
|
EP2277551B1
(en)
|
2002-09-06 |
2013-05-08 |
Cerulean Pharma Inc. |
Cyclodextrin-based polymers for delivering the therapeutic agents covalently bound thereto
|
|
WO2004039425A1
(ja)
*
|
2002-10-29 |
2004-05-13 |
Toray Industries, Inc. |
血管塞栓材料
|
|
US7407672B2
(en)
*
|
2002-11-04 |
2008-08-05 |
National Heart Center |
Composition derived from biological materials and method of use and preparation
|
|
US20040152769A1
(en)
*
|
2002-11-09 |
2004-08-05 |
Ekwuribe Nnochiri Nkem |
Modified carbamate-containing prodrugs and methods of synthesizing same
|
|
US7648962B2
(en)
*
|
2002-11-26 |
2010-01-19 |
Biocon Limited |
Natriuretic compounds, conjugates, and uses thereof
|
|
BR0316560A
(pt)
|
2002-11-26 |
2005-10-04 |
Nobex Corp |
Conjugado de composto natriurético, formulação farmacêutica, método de tratar uma condição, método de preparação do conjugado de composto natriurético, conjugado de peptìdeo pró-polinatriurético modificado, análogo de peptìdeo natriurético, análogo de hbnp, composto, e, método de preparar um composto
|
|
EP2368578A1
(en)
|
2003-01-09 |
2011-09-28 |
Macrogenics, Inc. |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
CA2512974A1
(en)
|
2003-01-13 |
2004-07-29 |
Macrogenics, Inc. |
Soluble fc.gamma.r fusion proteins and methods of use thereof
|
|
US20040208869A1
(en)
*
|
2003-01-30 |
2004-10-21 |
Medimmune, Inc. |
Uses of anti-integrin alphanubeta3 antibody formulations
|
|
DE10303974A1
(de)
|
2003-01-31 |
2004-08-05 |
Abbott Gmbh & Co. Kg |
Amyloid-β(1-42)-Oligomere, Verfahren zu deren Herstellung und deren Verwendung
|
|
KR20110094361A
(ko)
|
2003-04-11 |
2011-08-23 |
메디뮨 엘엘씨 |
재조합 il9 항체 및 그의 용도
|
|
US20050112087A1
(en)
*
|
2003-04-29 |
2005-05-26 |
Musso Gary F. |
Pharmaceutical formulations for sustained drug delivery
|
|
US20060193825A1
(en)
*
|
2003-04-29 |
2006-08-31 |
Praecis Phamaceuticals, Inc. |
Pharmaceutical formulations for sustained drug delivery
|
|
US8465537B2
(en)
*
|
2003-06-17 |
2013-06-18 |
Gel-Del Technologies, Inc. |
Encapsulated or coated stent systems
|
|
US7326571B2
(en)
*
|
2003-07-17 |
2008-02-05 |
Boston Scientific Scimed, Inc. |
Decellularized bone marrow extracellular matrix
|
|
US20050013870A1
(en)
*
|
2003-07-17 |
2005-01-20 |
Toby Freyman |
Decellularized extracellular matrix of conditioned body tissues and uses thereof
|
|
US20050048617A1
(en)
|
2003-08-18 |
2005-03-03 |
Medimmune, Inc. |
Humanization of antibodies
|
|
US20060228350A1
(en)
*
|
2003-08-18 |
2006-10-12 |
Medimmune, Inc. |
Framework-shuffling of antibodies
|
|
US8153591B2
(en)
*
|
2003-08-26 |
2012-04-10 |
Gel-Del Technologies, Inc. |
Protein biomaterials and biocoacervates and methods of making and using thereof
|
|
ITMI20031872A1
(it)
*
|
2003-09-30 |
2005-04-01 |
Mediolanum Farmaceutici Srl |
Copolimeri di poliesteri e polivinilpirrolidone.
|
|
EP2267062B1
(en)
*
|
2003-11-04 |
2017-10-25 |
SupraPolix B.V. |
Supramolecular polymers containing quadruple hydrogen bonding units in the polymer backbone
|
|
US20060053516A1
(en)
*
|
2003-12-05 |
2006-03-09 |
The University Of Hong Kong |
Genetically modified plants comprising SARS-CoV viral nucleotide sequences and methods of use thereof for immunization against SARS
|
|
WO2005055945A2
(en)
*
|
2003-12-08 |
2005-06-23 |
Gel-Del Technologies, Inc. |
Mucoadhesive drug delivery devices and methods of making and using thereof
|
|
CA2552241C
(en)
*
|
2003-12-30 |
2013-10-01 |
Durect Corporation |
Co-polymeric devices for controlled release of active agents
|
|
KR20050077916A
(ko)
|
2004-01-29 |
2005-08-04 |
학교법인 성균관대학 |
pH 및 온도 민감성 하이드로겔
|
|
WO2005108471A1
(en)
*
|
2004-05-05 |
2005-11-17 |
Firmenich Sa |
Biodegradable grafted copolymers
|
|
WO2005115489A2
(en)
*
|
2004-05-24 |
2005-12-08 |
Genzyme Corporation |
Adherent polymeric compositions
|
|
US8012457B2
(en)
|
2004-06-04 |
2011-09-06 |
Acusphere, Inc. |
Ultrasound contrast agent dosage formulation
|
|
US20050271727A1
(en)
*
|
2004-06-07 |
2005-12-08 |
Callisyn Pharmaceuticals, Inc. |
Biodegradable and biocompatible crosslinked polymer hydrogel prepared from PVA and/or PEG macromer mixtures
|
|
US20060004185A1
(en)
*
|
2004-07-01 |
2006-01-05 |
Leese Richard A |
Peptide antibiotics and peptide intermediates for their prepartion
|
|
US8268952B2
(en)
*
|
2004-07-12 |
2012-09-18 |
Suprapolix B.V. |
Supramolecular ionomers
|
|
CA2574709A1
(en)
|
2004-07-21 |
2006-02-02 |
Tulane University Health Sciences Center |
Treatment of renal dysfunction and multiple myeloma using pacap compounds
|
|
US8357391B2
(en)
*
|
2004-07-30 |
2013-01-22 |
Advanced Cardiovascular Systems, Inc. |
Coatings for implantable devices comprising poly (hydroxy-alkanoates) and diacid linkages
|
|
US20060034889A1
(en)
|
2004-08-16 |
2006-02-16 |
Macromed, Inc. |
Biodegradable diblock copolymers having reverse thermal gelation properties and methods of use thereof
|
|
WO2006047639A2
(en)
|
2004-10-27 |
2006-05-04 |
Medimmune, Inc. |
Modulation of antibody specificity by tailoring the affinity to cognate antigens
|
|
US20060115485A1
(en)
*
|
2004-10-29 |
2006-06-01 |
Medimmune, Inc. |
Methods of preventing and treating RSV infections and related conditions
|
|
US20060149363A1
(en)
*
|
2005-01-06 |
2006-07-06 |
Scimed Life Systems, Inc. |
Optimally expanded, collagen sealed ePTFE graft with improved tissue ingrowth
|
|
US8128952B2
(en)
*
|
2005-01-12 |
2012-03-06 |
Clemson University Research Foundation |
Ligand-mediated controlled drug delivery
|
|
WO2006076471A2
(en)
*
|
2005-01-12 |
2006-07-20 |
Nobex Corporation |
Bnp conjugates and methods of use
|
|
EP1869192B1
(en)
|
2005-03-18 |
2016-01-20 |
MedImmune, LLC |
Framework-shuffling of antibodies
|
|
KR100665672B1
(ko)
*
|
2005-04-13 |
2007-01-09 |
성균관대학교산학협력단 |
새로운 온도 및 pH 민감성 블록 공중합체 및 이를 이용한고분자 하이드로겔
|
|
ES2707152T3
(es)
|
2005-04-15 |
2019-04-02 |
Macrogenics Inc |
Diacuerpos covalentes y usos de los mismos
|
|
ES2376888T3
(es)
|
2005-05-04 |
2012-03-20 |
Suprapolix B.V. |
Materiales supramoleculares activos biológicamente, modulares biorreabsorbibles o biomédicos
|
|
ES2367583T3
(es)
*
|
2005-05-04 |
2011-11-10 |
Suprapolix B.V. |
Hidrogeles con enlaces de hidrógeno.
|
|
KR20080025174A
(ko)
|
2005-06-23 |
2008-03-19 |
메디뮨 인코포레이티드 |
응집 및 단편화 프로파일이 최적화된 항체 제제
|
|
CN103146708A
(zh)
*
|
2005-06-30 |
2013-06-12 |
Abbvie公司 |
Il-12/p40结合蛋白
|
|
HUE029465T2
(en)
|
2005-08-10 |
2017-02-28 |
Macrogenics Inc |
Identification and engineering of antibodies with variant Fc regions and methods of using same
|
|
US20090215992A1
(en)
*
|
2005-08-19 |
2009-08-27 |
Chengbin Wu |
Dual variable domain immunoglobulin and uses thereof
|
|
JP5364870B2
(ja)
|
2005-08-19 |
2013-12-11 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリン及びその使用
|
|
US7612181B2
(en)
|
2005-08-19 |
2009-11-03 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
US8362086B2
(en)
|
2005-08-19 |
2013-01-29 |
Merial Limited |
Long acting injectable formulations
|
|
EP2500353A3
(en)
|
2005-08-19 |
2012-10-10 |
Abbott Laboratories |
Dual variable domain immunoglobulin and uses thereof
|
|
CN101277974A
(zh)
|
2005-09-30 |
2008-10-01 |
阿伯特有限及两合公司 |
排斥性引导分子(rgm)蛋白质家族的蛋白质的结合结构域及其功能性片段和它们的用途
|
|
US20070078480A1
(en)
*
|
2005-10-04 |
2007-04-05 |
Boston Scientific Scimed, Inc. |
Self-expanding biodegradable or water-soluble vaso-occlusive devices
|
|
US20070078479A1
(en)
*
|
2005-10-04 |
2007-04-05 |
Boston Scientific Scimed, Inc. |
Self-expanding vaso-occlusive devices with regulated expansion
|
|
JP5398112B2
(ja)
*
|
2005-10-27 |
2014-01-29 |
東レ株式会社 |
生分解性粒子およびその製造方法
|
|
US20070106271A1
(en)
*
|
2005-11-09 |
2007-05-10 |
Searete Llc, A Limited Liability Corporation |
Remote control of substance delivery system
|
|
WO2007061896A1
(en)
|
2005-11-17 |
2007-05-31 |
Zogenix, Inc. |
Delivery of viscous formulations by needle-free injection
|
|
BRPI0619249A2
(pt)
|
2005-11-30 |
2011-09-20 |
Abbott Lab |
anticorpos anti-globulÈmeros-aß, frações que se ligam a antìgeno destes, hibridomas correspondentes, ácidos nucléicos, vetores, células hospedeiras, métodos de produzir os ditos anticorpos, composições compreendendo os ditos anticorpos, usos dos ditos anticorpos e métodos de usar os ditos anticorpos
|
|
US9486408B2
(en)
|
2005-12-01 |
2016-11-08 |
University Of Massachusetts Lowell |
Botulinum nanoemulsions
|
|
KR100738083B1
(ko)
*
|
2005-12-20 |
2007-07-12 |
삼성전자주식회사 |
마이크로어레이용 기판 및 그의 제조방법
|
|
WO2007074604A1
(ja)
|
2005-12-26 |
2007-07-05 |
Ltt Bio-Pharma Co., Ltd. |
水溶性非ペプチド性低分子薬物含有ナノ粒子
|
|
US20070178137A1
(en)
*
|
2006-02-01 |
2007-08-02 |
Toby Freyman |
Local control of inflammation
|
|
US20070239194A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Boston Scientific Scimed, Inc. |
Vaso-occlusive devices having expandable fibers
|
|
US20070280986A1
(en)
*
|
2006-06-01 |
2007-12-06 |
Carlos Gil |
Intra-operative coating of implants
|
|
MX2008015771A
(es)
|
2006-06-14 |
2009-01-27 |
Macrogenics Inc |
Metodos para el tratamiento de padecimientos autoinmunes usando anticuerpos monoclonales con toxicidad reducida.
|
|
AU2007281876B2
(en)
|
2006-06-26 |
2013-09-05 |
Macrogenics, Inc. |
FcgammaRIIB-specific antibodies and methods of use thereof
|
|
EA021255B1
(ru)
|
2006-08-28 |
2015-05-29 |
Киова Хакко Кирин Ко., Лимитед |
Антагонистические моноклональные антитела человека, специфичные в отношении light человека
|
|
PL3339445T3
(pl)
*
|
2006-09-08 |
2020-12-14 |
Abbvie Bahamas Ltd. |
Białka wiążące interleukinę 13
|
|
JP2010504318A
(ja)
*
|
2006-09-22 |
2010-02-12 |
ラボファーム インコーポレイテッド |
pH標的化薬剤送達のための組成物及び方法
|
|
EP2064335A4
(en)
|
2006-10-16 |
2011-03-30 |
Medimmune Llc |
MOLECULES WITH REDUCED HALF TIME, COMPOSITIONS AND ITS USE
|
|
US20080138397A1
(en)
*
|
2006-10-24 |
2008-06-12 |
Aradigm Corporation |
Processes for taste-masking of inhaled formulations
|
|
CA2667890C
(en)
*
|
2006-10-31 |
2015-01-27 |
Surmodics Pharmaceuticals, Inc. |
Spheronized polymer particles
|
|
EP2087027B1
(en)
|
2006-11-20 |
2011-10-05 |
SupraPolix B.V. |
Supramolecular polymers from low-melting, easily processable building blocks
|
|
US20080176958A1
(en)
|
2007-01-24 |
2008-07-24 |
Insert Therapeutics, Inc. |
Cyclodextrin-based polymers for therapeutics delivery
|
|
US8628789B2
(en)
*
|
2007-03-23 |
2014-01-14 |
Suprapolix, B.V. |
Strong reversible hydrogels
|
|
ATE515538T1
(de)
|
2007-03-23 |
2011-07-15 |
Suprapolix Bv |
Starke umkehrbare hydrogels
|
|
KR100838809B1
(ko)
*
|
2007-05-03 |
2008-06-17 |
성균관대학교산학협력단 |
겔강도가 우수한 온도 및 피에치 민감성 블록 공중합체 및이의 제조방법과 이를 이용한 약물전달체
|
|
KR101513318B1
(ko)
|
2007-05-14 |
2015-04-17 |
가부시키가이샤 엘티티 바이오파마 |
서방성의 음하전기를 갖는 저분자 약물 함유 나노 입자
|
|
US20080287633A1
(en)
*
|
2007-05-18 |
2008-11-20 |
Drumheller Paul D |
Hydrogel Materials
|
|
EP1997830A1
(en)
|
2007-06-01 |
2008-12-03 |
AIMM Therapeutics B.V. |
RSV specific binding molecules and means for producing them
|
|
CA2691434C
(en)
|
2007-06-21 |
2020-07-21 |
Macrogenics, Inc. |
Covalent diabodies and uses thereof
|
|
US20090155275A1
(en)
|
2007-07-31 |
2009-06-18 |
Medimmune, Llc |
Multispecific epitope binding proteins and uses thereof
|
|
KR100941774B1
(ko)
*
|
2007-09-06 |
2010-02-11 |
성균관대학교산학협력단 |
인체안전성이 우수한 온도 및 피에치 민감성 블록공중합체및 이의 제조방법과 이를 이용한 약물전달체
|
|
WO2009086483A2
(en)
*
|
2007-12-26 |
2009-07-09 |
Gel-Del Technologies, Inc. |
Biocompatible protein particles, particle devices and methods thereof
|
|
ES2613963T3
(es)
|
2008-01-18 |
2017-05-29 |
Medimmune, Llc |
Anticuerpos manipulados con cisteína para conjugación específica de sitio
|
|
US8962803B2
(en)
|
2008-02-29 |
2015-02-24 |
AbbVie Deutschland GmbH & Co. KG |
Antibodies against the RGM A protein and uses thereof
|
|
WO2009134336A1
(en)
*
|
2008-04-28 |
2009-11-05 |
Zogenix, Inc. |
Novel formulations for treatment of migraine
|
|
US20100260668A1
(en)
*
|
2008-04-29 |
2010-10-14 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
|
JP5646457B2
(ja)
|
2008-04-29 |
2014-12-24 |
アッヴィ・インコーポレイテッド |
二重可変ドメイン免疫グロブリン及びその使用
|
|
RU2518351C2
(ru)
|
2008-05-09 |
2014-06-10 |
Эббви Дойчланд Гмбх Унд Ко.Кг, |
Антитела к рецептору конечных продуктов глубокого гликирования (rage) и их применения
|
|
EP3002299A1
(en)
|
2008-06-03 |
2016-04-06 |
AbbVie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
PE20100054A1
(es)
|
2008-06-03 |
2010-03-03 |
Abbott Lab |
Inmunoglobulina con dominio variable dual
|
|
US8754213B2
(en)
*
|
2008-07-04 |
2014-06-17 |
Suprapolix B.V. |
High flow supramolecular compounds
|
|
RU2559525C2
(ru)
|
2008-07-08 |
2015-08-10 |
Эббви Инк |
Белки, связывающие простагландин е2, и их применение
|
|
MX2010014574A
(es)
*
|
2008-07-08 |
2011-04-27 |
Abbott Lab |
Inmunoglobulinas de dominio variable dual para prostaglandina e2 y usos de las mismas.
|
|
CN102143736A
(zh)
|
2008-07-17 |
2011-08-03 |
梅里亚有限公司 |
增强聚原酸酯和它们的制剂的稳定性的方法
|
|
KR100987693B1
(ko)
*
|
2008-10-20 |
2010-10-13 |
서울대학교산학협력단 |
폴리(에틸렌 글리콜)-b-[폴리(L-세린)-g-폴리(D,L-락티드)]의 블록공중합체 및 이를 이용한 약물전달체용 나노입자의 제조 방법
|
|
WO2010057177A2
(en)
|
2008-11-17 |
2010-05-20 |
Gel-Del Technologies, Inc. |
Protein biomaterial and biocoacervate vessel graft systems and methods of making and using thereof
|
|
US20100233079A1
(en)
*
|
2008-12-04 |
2010-09-16 |
Abbott Laboratories |
Dual Variable Domain Immunoglobulins and Uses Thereof
|
|
ES2733067T3
(es)
|
2008-12-19 |
2019-11-27 |
Macrogenics Inc |
Diacuerpos covalentes y usos de los mismos
|
|
AR074874A1
(es)
|
2008-12-23 |
2011-02-16 |
Biosource Pharm Inc |
Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto.
|
|
CN102369217A
(zh)
*
|
2009-01-29 |
2012-03-07 |
雅培制药有限公司 |
Il-1结合蛋白
|
|
US20110165063A1
(en)
*
|
2009-01-29 |
2011-07-07 |
Abbott Laboratories |
Il-1 binding proteins
|
|
US8030026B2
(en)
|
2009-02-24 |
2011-10-04 |
Abbott Laboratories |
Antibodies to troponin I and methods of use thereof
|
|
TW201613969A
(en)
*
|
2009-03-05 |
2016-04-16 |
Abbvie Inc |
IL-17 binding proteins
|
|
US8283162B2
(en)
|
2009-03-10 |
2012-10-09 |
Abbott Laboratories |
Antibodies relating to PIVKAII and uses thereof
|
|
WO2010141329A1
(en)
|
2009-06-01 |
2010-12-09 |
Medimmune, Llc |
Molecules with extended half-lives and uses thereof
|
|
CA2766405A1
(en)
|
2009-06-22 |
2011-01-13 |
Medimmune, Llc |
Engineered fc regions for site-specific conjugation
|
|
US8623358B2
(en)
|
2009-08-29 |
2014-01-07 |
Abbvie Inc. |
Therapeutic DLL4 binding proteins
|
|
AR078254A1
(es)
*
|
2009-09-01 |
2011-10-26 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
CA2939165A1
(en)
|
2009-09-15 |
2011-03-24 |
Cerulean Pharma Inc. |
A cdp-camptothecin conjugate, particle or composition and uses thereof
|
|
US8568726B2
(en)
|
2009-10-06 |
2013-10-29 |
Medimmune Limited |
RSV specific binding molecule
|
|
AU2010303415B2
(en)
|
2009-10-07 |
2015-02-19 |
Macrogenics, Inc. |
Fc region-containing polypeptides that exhibit improved effector function due to alterations of the extent of fucosylation, and methods for their use
|
|
MX2012004415A
(es)
|
2009-10-15 |
2012-05-08 |
Abbott Lab |
Inmunoglobulinas de dominio variable doble y usos de las mismas.
|
|
UY32979A
(es)
*
|
2009-10-28 |
2011-02-28 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
WO2011053707A1
(en)
*
|
2009-10-31 |
2011-05-05 |
Abbott Laboratories |
Antibodies to receptor for advanced glycation end products (rage) and uses thereof
|
|
US8916517B2
(en)
|
2009-11-02 |
2014-12-23 |
The Administrators Of The Tulane Educational Fund |
Analogs of pituitary adenylate cyclase-activating polypeptide (PACAP) and methods for their use
|
|
CA2780274C
(en)
|
2009-11-09 |
2018-06-26 |
Spotlight Technology Partners Llc |
Fragmented hydrogels
|
|
WO2011057131A1
(en)
|
2009-11-09 |
2011-05-12 |
Spotlight Technology Partners Llc |
Polysaccharide based hydrogels
|
|
EP2503888A4
(en)
*
|
2009-11-23 |
2015-07-29 |
Cerulean Pharma Inc |
POLYMERS ON CYCLODEXTRINBASIS FOR THERAPEUTIC ADMINISTRATION
|
|
KR20120118002A
(ko)
|
2009-12-08 |
2012-10-25 |
애보트 게엠베하 운트 콤파니 카게 |
망막 신경 섬유 층 변성의 치료에 사용하기 위한 rgm a 단백질에 대한 모노클로날 항체
|
|
EP2542582A4
(en)
|
2010-03-02 |
2013-12-04 |
Abbvie Inc |
THERAPEUTIC PROTEINS LINKING TO DLL4
|
|
EP2558494B1
(en)
|
2010-04-15 |
2018-05-23 |
AbbVie Inc. |
Amyloid-beta binding proteins
|
|
CA2798432A1
(en)
|
2010-05-06 |
2011-11-10 |
Novartis Ag |
Compositions and methods of use for therapeutic low density lipoprotein -related protein 6 (lrp6) antibodies
|
|
EA201291181A1
(ru)
|
2010-05-06 |
2013-05-30 |
Новартис Аг |
Композиции и способы применения терапевтических поливалентных антител против белка, родственного рецептору липопротеинов низкой плотности 6 (lrp6)
|
|
AU2011252883B2
(en)
|
2010-05-14 |
2015-09-10 |
Abbvie Inc. |
IL-1 binding proteins
|
|
CN103037903A
(zh)
|
2010-05-18 |
2013-04-10 |
天蓝制药公司 |
用于治疗自身免疫性疾病或其它疾病的组合物和方法
|
|
US8415307B1
(en)
|
2010-06-23 |
2013-04-09 |
Biosource Pharm, Inc. |
Antibiotic compositions for the treatment of gram negative infections
|
|
WO2012006500A2
(en)
|
2010-07-08 |
2012-01-12 |
Abbott Laboratories |
Monoclonal antibodies against hepatitis c virus core protein
|
|
UY33492A
(es)
|
2010-07-09 |
2012-01-31 |
Abbott Lab |
Inmunoglobulinas con dominio variable dual y usos de las mismas
|
|
US9120862B2
(en)
|
2010-07-26 |
2015-09-01 |
Abbott Laboratories |
Antibodies relating to PIVKA-II and uses thereof
|
|
MX339622B
(es)
|
2010-08-02 |
2016-06-02 |
Macrogenics Inc |
Diacuerpos covalentes y sus usos.
|
|
US8735546B2
(en)
|
2010-08-03 |
2014-05-27 |
Abbvie Inc. |
Dual variable domain immunoglobulins and uses thereof
|
|
CN105348387B
(zh)
|
2010-08-14 |
2020-08-25 |
Abbvie 公司 |
β淀粉样蛋白结合蛋白
|
|
WO2012024650A2
(en)
|
2010-08-19 |
2012-02-23 |
Abbott Laboratories |
Anti-ngf antibodies and their use
|
|
SG187908A1
(en)
|
2010-08-20 |
2013-03-28 |
Novartis Ag |
Antibodies for epidermal growth factor receptor 3 (her3)
|
|
PH12013500337A1
(en)
|
2010-08-26 |
2017-08-23 |
Abbvie Inc |
Dual variable domain immunoglobulins and uses thereof
|
|
JP5999567B2
(ja)
|
2010-10-20 |
2016-09-28 |
ディーエスエム アイピー アセッツ ビー.ブイ. |
ペンダント型親水性物質を有する生分解性組成物および関連デバイス
|
|
EP2450394B1
(en)
|
2010-11-05 |
2017-06-07 |
SupraPolix B.V. |
A process for the preparation of a supramolecular polymer
|
|
US20130245233A1
(en)
|
2010-11-24 |
2013-09-19 |
Ming Lei |
Multispecific Molecules
|
|
EP2650026B1
(en)
|
2010-12-09 |
2019-03-27 |
Toray Industries, Inc. |
Biodegradable particles, vascular occlusion material, and method for producing biodegradable particles
|
|
JPWO2012086569A1
(ja)
|
2010-12-20 |
2014-05-22 |
東レ株式会社 |
医療用生分解性粒子及び血管塞栓材料
|
|
TW201307388A
(zh)
|
2010-12-21 |
2013-02-16 |
Abbott Lab |
Il-1結合蛋白
|
|
WO2012121775A2
(en)
|
2010-12-21 |
2012-09-13 |
Abbott Laboratories |
Dual variable domain immunoglobulins and uses thereof
|
|
MX347090B
(es)
|
2010-12-29 |
2017-04-11 |
Medincell |
Composiciones de suministro de farmacos biodegradables.
|
|
CA2831414C
(en)
|
2011-03-30 |
2016-03-22 |
Toray Industries, Inc. |
Biodegradable particle, vascular embolization material and method for producing biodegradable particles
|
|
SI2699264T1
(en)
|
2011-04-20 |
2018-08-31 |
Medimmune Llc |
Antibodies and other molecules that bind b7-h1 and pd-1
|
|
EA201391753A1
(ru)
|
2011-05-21 |
2014-08-29 |
Макродженикс, Инк. |
Домены, связывающиеся с деиммунизованной сывороткой, и их применение для увеличения времени полужизни в сыворотке
|
|
US8974560B2
(en)
|
2011-06-30 |
2015-03-10 |
Saint-Gobain Abrasives, Inc. |
Coated abrasive aggregates and products containg same
|
|
RU2640025C2
(ru)
|
2011-07-13 |
2017-12-25 |
Эббви Инк. |
Способы и композиции для лечения астмы с использованием антител против il-13
|
|
WO2013025779A1
(en)
|
2011-08-15 |
2013-02-21 |
Amplimmune, Inc. |
Anti-b7-h4 antibodies and their uses
|
|
BR112014006929A2
(pt)
|
2011-09-23 |
2017-04-04 |
Technophage Investigação E Desenvolvimento Em Biotecnologia Sa |
agentes anti-fator de necrose tumoral-alfa e seus usos
|
|
EP2771360A1
(en)
|
2011-10-24 |
2014-09-03 |
AbbVie Inc. |
Immunobinders directed against sclerostin
|
|
KR102083957B1
(ko)
|
2011-12-05 |
2020-03-04 |
노파르티스 아게 |
표피 성장 인자 수용체 3 (her3)에 대한 항체
|
|
JP2015500829A
(ja)
|
2011-12-05 |
2015-01-08 |
ノバルティス アーゲー |
上皮細胞増殖因子受容体3(her3)のドメインiiに対するher3の抗体
|
|
CN104144947B
(zh)
|
2011-12-14 |
2017-10-27 |
艾伯维德国有限责任两合公司 |
用于诊断和治疗铁相关病症的组合物和方法
|
|
EP2791175A2
(en)
|
2011-12-14 |
2014-10-22 |
Abbvie Deutschland GmbH & Co. KG |
Composition and method for the diagnosis and treatment of iron-related disorders
|
|
EP3539982B1
(en)
|
2011-12-23 |
2025-02-19 |
Pfizer Inc. |
Engineered antibody constant regions for site-specific conjugation and methods and uses therefor
|
|
US9120870B2
(en)
|
2011-12-30 |
2015-09-01 |
Abbvie Inc. |
Dual specific binding proteins directed against IL-13 and IL-17
|
|
EP3369746A1
(en)
|
2012-01-27 |
2018-09-05 |
AbbVie Deutschland GmbH & Co KG |
Composition and method for diagnosis and treatment of diseases associated with neurite degeneration
|
|
KR20130090950A
(ko)
|
2012-02-07 |
2013-08-16 |
성균관대학교산학협력단 |
듀얼 전이 고분자 하이드로젤 및 이의 이용
|
|
US10179173B2
(en)
*
|
2012-03-23 |
2019-01-15 |
Regents Of The University Of Minnesota |
Semi-solid delivery systems
|
|
CN104185480B
(zh)
|
2012-03-28 |
2016-04-20 |
东丽株式会社 |
生物降解性材料以及生物降解性材料的制造方法
|
|
JP6191455B2
(ja)
|
2012-03-28 |
2017-09-06 |
東レ株式会社 |
生分解性材料及び生分解性材料の製造方法
|
|
SG11201407017WA
(en)
|
2012-06-04 |
2014-12-30 |
Irm Llc |
Site-specific labeling methods and molecules produced thereby
|
|
TW201402608A
(zh)
|
2012-07-12 |
2014-01-16 |
Abbvie Inc |
Il-1結合蛋白質
|
|
US20140094432A1
(en)
|
2012-10-02 |
2014-04-03 |
Cerulean Pharma Inc. |
Methods and systems for polymer precipitation and generation of particles
|
|
AU2013337775B2
(en)
|
2012-11-01 |
2017-03-30 |
Abbvie Inc. |
Anti-VEGF/DLL4 dual variable domain immunoglobulins and uses thereof
|
|
KR20150082503A
(ko)
|
2012-11-09 |
2015-07-15 |
화이자 인코포레이티드 |
혈소판 유래 성장 인자 b 특이적 항체, 및 그의 조성물 및 용도
|
|
JP2016509582A
(ja)
|
2012-12-19 |
2016-03-31 |
アンプリミューン, インコーポレイテッド |
抗ヒトb7−h4抗体およびその使用
|
|
BR112015014621A2
(pt)
|
2012-12-21 |
2017-10-03 |
Amplimmune Inc |
Anticorpos anti-h7cr
|
|
WO2014124258A2
(en)
|
2013-02-08 |
2014-08-14 |
Irm Llc |
Specific sites for modifying antibodies to make immunoconjugates
|
|
CA2900755C
(en)
|
2013-02-08 |
2021-07-20 |
Irm Llc |
Specific sites for modifying antibodies to make immunoconjugates
|
|
US9498532B2
(en)
|
2013-03-13 |
2016-11-22 |
Novartis Ag |
Antibody drug conjugates
|
|
JP6505076B2
(ja)
|
2013-03-14 |
2019-04-24 |
アボット・ラボラトリーズAbbott Laboratories |
Hcv抗原−抗体組み合わせアッセイおよびこれに使用するための方法および組成物
|
|
JP2016514130A
(ja)
|
2013-03-14 |
2016-05-19 |
ノバルティス アーゲー |
Notch3に対する抗体
|
|
EP2970947A4
(en)
|
2013-03-14 |
2016-10-12 |
Abbott Lab |
RECOMBINANT HCV NS3 ANTIGENS AND THEIR MUTANTS FOR ENHANCED ANTIBODY DETECTION
|
|
CN105378099B
(zh)
|
2013-03-14 |
2021-05-11 |
雅培制药有限公司 |
Hcv核心脂质结合结构域单克隆抗体
|
|
BR112015021134A2
(pt)
|
2013-03-15 |
2017-10-10 |
Novartis Ag |
conjugados de fármaco e anticorpo
|
|
US9469686B2
(en)
|
2013-03-15 |
2016-10-18 |
Abbott Laboratories |
Anti-GP73 monoclonal antibodies and methods of obtaining the same
|
|
EP2970459A2
(en)
|
2013-03-15 |
2016-01-20 |
AbbVie Inc. |
Dual specific binding proteins directed against il-1beta and il-17
|
|
MX376808B
(es)
|
2013-05-24 |
2025-03-07 |
Medimmune Llc |
Anticuerpos anti-b7-h5 y sus usos.
|
|
SG10201708143QA
(en)
|
2013-06-06 |
2017-11-29 |
Pf Medicament |
Anti-c10orf54 antibodies and uses thereof
|
|
WO2014197885A2
(en)
|
2013-06-07 |
2014-12-11 |
Duke University |
Inhibitors of complement factor h
|
|
US11384149B2
(en)
|
2013-08-09 |
2022-07-12 |
Macrogenics, Inc. |
Bi-specific monovalent Fc diabodies that are capable of binding CD32B and CD79b and uses thereof
|
|
UA116479C2
(uk)
|
2013-08-09 |
2018-03-26 |
Макродженікс, Інк. |
БІСПЕЦИФІЧНЕ МОНОВАЛЕНТНЕ Fc-ДІАТІЛО, ЯКЕ ОДНОЧАСНО ЗВ'ЯЗУЄ CD32B I CD79b, ТА ЙОГО ЗАСТОСУВАННЯ
|
|
EP2840091A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific diabodies that are capable of binding gpA33 and CD3 and uses thereof
|
|
EP2839842A1
(en)
|
2013-08-23 |
2015-02-25 |
MacroGenics, Inc. |
Bi-specific monovalent diabodies that are capable of binding CD123 and CD3 and uses thereof
|
|
WO2015058868A1
(en)
|
2013-10-25 |
2015-04-30 |
Pangaea Biotech, S.L. |
Compositions and methods for the treatment of cancer
|
|
GB201318990D0
(en)
|
2013-10-28 |
2013-12-11 |
Omg Plc |
Optical sighting
|
|
EP3068801A1
(en)
|
2013-11-13 |
2016-09-21 |
Pfizer Inc. |
Tumor necrosis factor-like ligand 1a specific antibodies and compositions and uses thereof
|
|
WO2015084883A2
(en)
|
2013-12-02 |
2015-06-11 |
Abbvie, Inc. |
Compositions and methods for treating osteoarthritis
|
|
WO2015109212A1
(en)
|
2014-01-17 |
2015-07-23 |
Pfizer Inc. |
Anti-il-2 antibodies and compositions and uses thereof
|
|
PL3097122T3
(pl)
|
2014-01-24 |
2020-10-19 |
Ngm Biopharmaceuticals, Inc. |
Przeciwciała wiążące domenę 2 beta klotho oraz sposoby ich stosowania
|
|
KR20160135190A
(ko)
|
2014-02-14 |
2016-11-25 |
앤드류 에스. 카이 |
혈관형성 암의 치료를 위한 개선된 방법
|
|
EP3450571B1
(en)
|
2014-02-24 |
2023-04-05 |
Celgene Corporation |
Methods of using an activator of cereblon for neural cell expansion and the treatment of central nervous system disorders
|
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
|
WO2015138337A1
(en)
|
2014-03-09 |
2015-09-17 |
Abbvie, Inc. |
Compositions and methods for treating rheumatoid arthritis
|
|
CN106659800A
(zh)
|
2014-03-12 |
2017-05-10 |
诺华股份有限公司 |
用于修饰抗体以制备免疫缀合物的特定位点
|
|
EP3142700B1
(en)
|
2014-05-16 |
2021-03-03 |
Medimmune, LLC |
Molecules with altered neonate fc receptor binding having enhanced therapeutic and diagnostic properties
|
|
SG10201913680PA
(en)
|
2014-05-29 |
2020-03-30 |
Macrogenics Inc |
Tri-specific binding molecules that specifically bind to multiple cancer antigens and methods of use thereof
|
|
TWI693232B
(zh)
|
2014-06-26 |
2020-05-11 |
美商宏觀基因股份有限公司 |
與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
|
|
JP6755235B2
(ja)
|
2014-07-16 |
2020-09-16 |
デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド |
低悪性度漿液性癌におけるher3阻害
|
|
WO2016020791A1
(en)
|
2014-08-05 |
2016-02-11 |
Novartis Ag |
Ckit antibody drug conjugates
|
|
PE20170903A1
(es)
|
2014-08-12 |
2017-07-12 |
Novartis Ag |
Conjugados de farmacos con anticuerpos anti-cdh6
|
|
AP2017009823A0
(en)
|
2014-09-26 |
2017-03-31 |
Macrogenics Inc |
Bi-specific monovalent diabodies that are capable of binding cd19 and cd3, and uses thereof
|
|
PE20170912A1
(es)
|
2014-11-14 |
2017-07-12 |
Novartis Ag |
Conjugados de anticuerpo-farmaco
|
|
CN107208120B
(zh)
|
2014-12-09 |
2021-11-23 |
斯威特沃特能源公司 |
快速预处理
|
|
US10093733B2
(en)
|
2014-12-11 |
2018-10-09 |
Abbvie Inc. |
LRP-8 binding dual variable domain immunoglobulin proteins
|
|
WO2016094837A2
(en)
|
2014-12-11 |
2016-06-16 |
Igenica Biotherapeutics, Inc. |
Anti-c10orf54 antibodies and uses thereof
|
|
CN104479157B
(zh)
*
|
2015-01-06 |
2017-07-11 |
山东理工大学 |
一种聚己内酯与聚乙二醇改进聚肽膜亲水性与柔顺性的方法
|
|
WO2016118921A1
(en)
|
2015-01-24 |
2016-07-28 |
Abbvie, Inc. |
Compositions and methods for treating psoriatic arthritis
|
|
HK1247215A1
(zh)
|
2015-01-26 |
2018-09-21 |
Macrogenics, Inc. |
包含dr5-结合结构域的多价分子
|
|
KR102740384B1
(ko)
|
2015-03-03 |
2024-12-06 |
키맵 리미티드 |
항체, 용도 및 방법
|
|
RU2715597C2
(ru)
|
2015-05-29 |
2020-03-02 |
Эббви Инк. |
Антитела к cd40 и способы их применения
|
|
TWI773646B
(zh)
|
2015-06-08 |
2022-08-11 |
美商宏觀基因股份有限公司 |
結合lag-3的分子和其使用方法
|
|
TW201710286A
(zh)
|
2015-06-15 |
2017-03-16 |
艾伯維有限公司 |
抗vegf、pdgf及/或其受體之結合蛋白
|
|
WO2016203432A1
(en)
|
2015-06-17 |
2016-12-22 |
Novartis Ag |
Antibody drug conjugates
|
|
US11066481B2
(en)
|
2015-07-23 |
2021-07-20 |
The Regents Of The University Of California |
Antibodies to coagulation factor XIa and uses thereof
|
|
AU2016298227B9
(en)
|
2015-07-30 |
2019-10-31 |
Macrogenics, Inc. |
PD-1-binding molecules and methods of use thereof
|
|
US9862760B2
(en)
|
2015-09-16 |
2018-01-09 |
Novartis Ag |
Polyomavirus neutralizing antibodies
|
|
EP3355920A4
(en)
|
2015-09-29 |
2019-05-15 |
Celgene Corporation |
PD-1 BINDING PROTEINS AND METHOD OF USE THEREOF
|
|
WO2017070561A1
(en)
|
2015-10-23 |
2017-04-27 |
Pfizer Inc. |
Anti-il-2 antibodies and compositions and uses thereof
|
|
EP3370694A1
(en)
|
2015-11-06 |
2018-09-12 |
Fraunhofer Gesellschaft zur Förderung der angewandten Forschung e.V. |
Composition comprising a biocompatible and biodegradable polymer, nanocarries and a drug and methods of making and using the same
|
|
EP4374861A3
(en)
|
2015-11-16 |
2024-08-07 |
MedinCell S.A. |
A method for morselizing and/or targeting pharmaceutically active principles to synovial tissue
|
|
EP3383908A1
(en)
|
2015-12-02 |
2018-10-10 |
Stsciences, Inc. |
Antibodies specific to glycosylated btla (b- and t- lymphocyte attenuator)
|
|
MX2018006613A
(es)
|
2015-12-02 |
2019-01-30 |
Stcube & Co Inc |
Anticuerpos y moleculas que se unen inmunoespecificamente a btn1a1 y los usos terapeuticos de los mismos.
|
|
JP6955507B2
(ja)
|
2015-12-14 |
2021-10-27 |
マクロジェニクス,インコーポレーテッド |
Pd‐1及びctla‐4との免疫応答性を有する二重特異性並びにその使用方法
|
|
EP3405492B1
(en)
|
2016-01-21 |
2020-10-21 |
Novartis AG |
Multispecific molecules targeting cll-1
|
|
TWI762487B
(zh)
|
2016-06-08 |
2022-05-01 |
美商艾伯維有限公司 |
抗-b7-h3抗體及抗體藥物結合物
|
|
EP3468598A1
(en)
|
2016-06-08 |
2019-04-17 |
AbbVie Inc. |
Anti-cd98 antibodies and antibody drug conjugates
|
|
CA3027044A1
(en)
|
2016-06-08 |
2017-12-14 |
Abbvie Inc. |
Anti-b7-h3 antibodies and antibody drug conjugates
|
|
WO2018053405A1
(en)
|
2016-09-19 |
2018-03-22 |
Celgene Corporation |
Methods of treating immune disorders using pd-1 binding proteins
|
|
EP3515943A4
(en)
|
2016-09-19 |
2020-05-06 |
Celgene Corporation |
METHODS OF TREATING VITILIGO WITH PD-1 BINDING PROTEINS
|
|
US11779604B2
(en)
|
2016-11-03 |
2023-10-10 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses and methods
|
|
EP3541358A1
(en)
|
2016-11-21 |
2019-09-25 |
Eirion Therapeutics, Inc. |
Transdermal delivery of large agents
|
|
EP3544628A4
(en)
|
2016-11-23 |
2020-11-18 |
Immunoah Therapeutics, Inc. |
4-1BB BINDING PROTEINS AND THEIR USES
|
|
JOP20190187A1
(ar)
|
2017-02-03 |
2019-08-01 |
Novartis Ag |
مترافقات عقار جسم مضاد لـ ccr7
|
|
US11821047B2
(en)
|
2017-02-16 |
2023-11-21 |
Apalta Patent OÜ |
High pressure zone formation for pretreatment
|
|
WO2018185618A1
(en)
|
2017-04-03 |
2018-10-11 |
Novartis Ag |
Anti-cdh6 antibody drug conjugates and anti-gitr antibody combinations and methods of treatment
|
|
US10865238B1
(en)
|
2017-05-05 |
2020-12-15 |
Duke University |
Complement factor H antibodies
|
|
WO2018222685A1
(en)
|
2017-05-31 |
2018-12-06 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that immunospecifically bind to btn1a1
|
|
KR20250036941A
(ko)
|
2017-05-31 |
2025-03-14 |
주식회사 에스티큐브앤컴퍼니 |
Btn1a1에 면역특이적으로 결합하는 항체 및 분자 및 이의 치료적 용도
|
|
EP3635007A1
(en)
|
2017-06-06 |
2020-04-15 |
STCube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that bind to btn1a1 or btn1a1-ligands
|
|
BR112020010753A2
(pt)
|
2017-12-01 |
2020-11-24 |
The Regents Of The University Of California |
anticorpos anti-cxcr5 e composições e usos dos mesmos
|
|
CA3083363A1
(en)
|
2017-12-01 |
2019-06-06 |
Novartis Ag |
Polyomavirus neutralizing antibodies
|
|
MX2020009526A
(es)
|
2018-03-12 |
2020-10-28 |
Zoetis Services Llc |
Anticuerpos anti-ngf y metodos de estos.
|
|
CA3094756A1
(en)
|
2018-03-29 |
2019-10-03 |
Pfizer Inc. |
Lfa3 variants and compositions and uses thereof
|
|
US10654944B2
(en)
|
2018-04-10 |
2020-05-19 |
Y-Biologics Inc. |
Cell engaging binding molecules
|
|
CN112165974B
(zh)
|
2018-05-31 |
2024-11-08 |
诺华股份有限公司 |
乙型肝炎抗体
|
|
AU2019277029C1
(en)
|
2018-06-01 |
2024-01-04 |
Novartis Ag |
Binding molecules against BCMA and uses thereof
|
|
EP3807321A4
(en)
|
2018-06-18 |
2022-03-02 |
Anwita Biosciences, Inc. |
ANTI-MESOTHELIN CONSTRUCTS AND USES THEREOF
|
|
IL280199B2
(en)
|
2018-07-20 |
2025-08-01 |
Pf Medicament |
Receptor for vista
|
|
US11359024B2
(en)
|
2018-09-07 |
2022-06-14 |
Pfizer Inc. |
Anti-AVB8 antibodies and compositions and uses thereof
|
|
WO2020053742A2
(en)
|
2018-09-10 |
2020-03-19 |
Novartis Ag |
Anti-hla-hbv peptide antibodies
|
|
TW202028237A
(zh)
|
2018-09-27 |
2020-08-01 |
美商西建公司 |
SIRPα結合蛋白及其使用方法
|
|
US12492250B2
(en)
|
2018-09-28 |
2025-12-09 |
Emory University |
suPAR and prediction and treatment of acute kidney injury
|
|
TW202039554A
(zh)
|
2018-12-19 |
2020-11-01 |
瑞士商諾華公司 |
抗TNF-α抗體
|
|
PH12021551479A1
(en)
|
2018-12-21 |
2022-07-18 |
Novartis Ag |
Antibodies to pmel17 and conjugates thereof
|
|
KR102563319B1
(ko)
|
2019-03-08 |
2023-08-03 |
앱티스 주식회사 |
위치특이적 항체 콘쥬게이션 및 이의 구체예로서의 항체-약물 콘쥬게이트
|
|
WO2020205827A1
(en)
|
2019-04-01 |
2020-10-08 |
Rush University Medical Center |
Reagents and assays using modified integrin domains
|
|
TW202102526A
(zh)
|
2019-04-04 |
2021-01-16 |
美商銳進科斯生物股份有限公司 |
重組腺相關病毒及其用途
|
|
EP4004214A1
(en)
|
2019-07-26 |
2022-06-01 |
RegenxBio Inc. |
Engineered nucleic acid regulatory element and methods of uses thereof
|
|
CN114729045B
(zh)
|
2019-09-26 |
2025-09-09 |
斯特库比公司 |
对糖基化的ctla-4特异性的抗体及其使用方法
|
|
CN110615829B
(zh)
*
|
2019-09-29 |
2022-07-19 |
深圳市三浦天然化妆品有限公司 |
一种自组装抗菌肽水凝胶
|
|
CN114829404B
(zh)
|
2019-10-09 |
2025-09-09 |
斯特库比公司 |
对糖基化的lag3特异的抗体及其使用方法
|
|
US11692000B2
(en)
|
2019-12-22 |
2023-07-04 |
Apalta Patents OÜ |
Methods of making specialized lignin and lignin products from biomass
|
|
US20230181756A1
(en)
|
2020-04-30 |
2023-06-15 |
Novartis Ag |
Ccr7 antibody drug conjugates for treating cancer
|
|
US20230167193A1
(en)
|
2020-05-01 |
2023-06-01 |
Novartis Ag |
Immunoglobulin variants
|
|
US20230242647A1
(en)
|
2020-05-01 |
2023-08-03 |
Novartis Ag |
Engineered immunoglobulins
|
|
KR20230012539A
(ko)
|
2020-05-13 |
2023-01-26 |
디스크 메디슨, 인크. |
골수섬유증을 치료하기 위한 항-헤모주벨린 (hjv) 항체
|
|
CN116157510A
(zh)
|
2020-06-17 |
2023-05-23 |
詹森生物科技公司 |
用于制造多能干细胞的材料和方法
|
|
WO2022012680A1
(en)
|
2020-07-16 |
2022-01-20 |
Nanjing Legend Biotech Co., Ltd. |
Cd20 binding molecules and uses thereof
|
|
WO2022031576A1
(en)
|
2020-08-03 |
2022-02-10 |
Janssen Biotech, Inc. |
Materials and methods for multidirectional biotransportation in virotherapeutics
|
|
WO2022029220A1
(en)
|
2020-08-05 |
2022-02-10 |
Ellipses Pharma Ltd |
Treatment of cancer using a cyclodextrin-containing polymer-topoisomerase inhibitor conjugate and a parp inhibitor
|
|
CA3190987A1
(en)
|
2020-08-10 |
2022-02-17 |
Janssen Biotech, Inc. |
Materials and methods for producing bioengineered virus specific lymphocytes
|
|
WO2022076750A2
(en)
|
2020-10-07 |
2022-04-14 |
Regenxbio Inc. |
Recombinant adeno-associated viruses for cns or muscle delivery
|
|
AU2021356667A1
(en)
|
2020-10-07 |
2023-06-08 |
Regenxbio Inc. |
Adeno-associated viruses for ocular delivery of gene therapy
|
|
US12383246B2
(en)
|
2020-10-12 |
2025-08-12 |
Abbott Cardiovascular Systems, Inc. |
Vessel closure device with improved safety and tract hemostasis
|
|
JP2023547499A
(ja)
|
2020-11-06 |
2023-11-10 |
ノバルティス アーゲー |
抗体Fc変異体
|
|
AU2021374083A1
(en)
|
2020-11-06 |
2023-06-01 |
Novartis Ag |
Anti-cd19 agent and b cell targeting agent combination therapy for treating b cell malignancies
|
|
EP4240491A1
(en)
|
2020-11-06 |
2023-09-13 |
Novartis AG |
Cd19 binding molecules and uses thereof
|
|
JP2024502832A
(ja)
|
2020-12-31 |
2024-01-23 |
アラマー バイオサイエンシーズ, インコーポレイテッド |
高親和性及び/または特異性を有する結合剤分子ならびにその製造及び使用方法
|
|
AR124681A1
(es)
|
2021-01-20 |
2023-04-26 |
Abbvie Inc |
Conjugados anticuerpo-fármaco anti-egfr
|
|
GB202103785D0
(en)
*
|
2021-03-18 |
2021-05-05 |
UCB Biopharma SRL |
Formulations
|
|
WO2022221720A1
(en)
|
2021-04-16 |
2022-10-20 |
Novartis Ag |
Antibody drug conjugates and methods for making thereof
|
|
CN113354800A
(zh)
*
|
2021-06-22 |
2021-09-07 |
山东谷雨春生物科技有限公司 |
一种peg嵌段聚乙丙交酯及其应用
|
|
EP4413019A2
(en)
|
2021-10-07 |
2024-08-14 |
RegenxBio Inc. |
Recombinant adeno-associated viruses for cns tropic delivery
|
|
EP4413018A1
(en)
|
2021-10-07 |
2024-08-14 |
RegenxBio Inc. |
Recombinant adeno-associated viruses for targeted delivery
|
|
CN118119642A
(zh)
|
2021-10-28 |
2024-05-31 |
诺华股份有限公司 |
工程化Fc变体
|
|
WO2023077092A1
(en)
|
2021-10-28 |
2023-05-04 |
Regenxbio Inc. |
Engineered nucleic acid regulatory elements and methods and uses thereof
|
|
UY40097A
(es)
|
2022-01-07 |
2023-07-14 |
Johnson & Johnson Entpr Innovation Inc |
Materiales y métodos de proteínas de unión a il-1b
|
|
CA3251397A1
(en)
|
2022-02-09 |
2023-08-17 |
Janssen Biotech, Inc. |
METHODS AND COMPOSITIONS COMPRISING COMPONENTS FOR BRINGING BISORPOSE VΒ17 T LYMPHOCYTES TO CONTACT WITH BIOMODIFIED VIRUS-SPECIFIC LYMPHOCYTES
|
|
KR102707065B1
(ko)
|
2022-03-08 |
2024-09-19 |
동국제약 주식회사 |
코아세르베이션법을 이용하여 현탁성이 개선된 미립구의 제조방법
|
|
WO2023178053A1
(en)
|
2022-03-13 |
2023-09-21 |
Regenxbio Inc. |
Modified muscle-specific promoters
|
|
US20250249127A1
(en)
|
2022-04-14 |
2025-08-07 |
Regenxbio Inc. |
Gene therapy for treating an ocular disease
|
|
WO2023201277A1
(en)
|
2022-04-14 |
2023-10-19 |
Regenxbio Inc. |
Recombinant adeno-associated viruses for cns tropic delivery
|
|
US20250277004A1
(en)
|
2022-04-18 |
2025-09-04 |
Regenxbio Inc. |
Hybrid aav capsids
|
|
WO2023209568A1
(en)
|
2022-04-26 |
2023-11-02 |
Novartis Ag |
Multispecific antibodies targeting il-13 and il-18
|
|
EP4554969A1
(en)
|
2022-07-15 |
2025-05-21 |
Janssen Biotech, Inc. |
Material and methods for improved bioengineered pairing of antigen-binding variable regions
|
|
US20250188492A1
(en)
|
2022-07-22 |
2025-06-12 |
Janssen Biotech, Inc. |
Enhanced Transfer of Genetic Instructions to Effector Immune Cells
|
|
JP2025525969A
(ja)
|
2022-08-05 |
2025-08-07 |
ヤンセン バイオテツク,インコーポレーテツド |
脳腫瘍を治療するためのcd98結合構築物
|
|
CA3263784A1
(en)
|
2022-08-05 |
2024-02-08 |
Janssen Biotech, Inc. |
TRANSFERRIN RECEPTOR BINDING PROTEINS FOR THE TREATMENT OF BRAIN TUMORS
|
|
US20260055144A1
(en)
|
2022-08-24 |
2026-02-26 |
Regenxbio Inc. |
Recombinant adeno-associated viruses and uses thereof
|
|
JP2025534666A
(ja)
|
2022-10-11 |
2025-10-17 |
リジェネックスバイオ インコーポレイテッド |
操作された核酸調節エレメントならびにその使用方法
|
|
TW202448505A
(zh)
|
2023-03-01 |
2024-12-16 |
美商普泛森生技公司 |
用於治療第1型糖尿病的方法及組成物
|
|
TW202506177A
(zh)
|
2023-03-30 |
2025-02-16 |
美商普泛森生技公司 |
減少外源性胰島素使用之方法
|
|
WO2024216244A2
(en)
|
2023-04-13 |
2024-10-17 |
Regenxbio Inc. |
Targeting aav capsids, methods of manufacturing and using same
|
|
WO2024238853A1
(en)
|
2023-05-16 |
2024-11-21 |
Regenxbio Inc. |
Adeno-associated viruses for ocular delivery of gene therapy
|
|
AU2024299422A1
(en)
|
2023-07-27 |
2026-03-12 |
Provention Bio, Inc. |
Methods for treating type 1 diabetes
|
|
WO2025108407A2
(en)
|
2023-11-23 |
2025-05-30 |
Neuexcell Therapeutics (Suzhou) Co., Ltd. |
Gene therapy compositions and methods for treating glioma
|
|
WO2025217214A2
(en)
|
2024-04-08 |
2025-10-16 |
Regenxbio Inc. |
Recombinant adeno-associated viruses and uses thereof
|
|
WO2025262564A1
(en)
|
2024-06-17 |
2025-12-26 |
Pfizer Inc. |
Use of anti-cxcr5 antibodies
|
|
WO2026058155A1
(en)
|
2024-09-11 |
2026-03-19 |
Novartis Ag |
Antibodies targeting il-31
|
|
CN121896173A
(zh)
|
2024-10-21 |
2026-04-21 |
深圳市湾岛细胞科技有限公司 |
表达外源肌苷单磷酸脱氢酶的真核细胞
|