|
US4444784A
(en)
*
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
JPS56150037A
(en)
|
1980-04-22 |
1981-11-20 |
Sankyo Co Ltd |
Hydronaphthalene compound
|
|
US4432996A
(en)
*
|
1980-11-17 |
1984-02-21 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products and process of preparation
|
|
JPS57185275A
(en)
*
|
1981-05-07 |
1982-11-15 |
Sankyo Co Ltd |
Tetrahydro-dum-4 and tetrahydro-isodum-4 and their derivatives
|
|
JPS57185276A
(en)
*
|
1981-05-11 |
1982-11-15 |
Sankyo Co Ltd |
Dihydro-dum-4 and dihydro-isodum-4 and their derivative
|
|
JPS5815968A
(ja)
*
|
1981-07-21 |
1983-01-29 |
Sankyo Co Ltd |
Ml−236b誘導体およびその製法
|
|
JPS5835144A
(ja)
*
|
1981-08-27 |
1983-03-01 |
Sankyo Co Ltd |
Mb−530b誘導体およびその製造法
|
|
JPS5889191A
(ja)
*
|
1981-11-20 |
1983-05-27 |
Sankyo Co Ltd |
3−ヒドロキシ−ml−236b誘導体の製造法
|
|
PH20405A
(en)
*
|
1983-07-21 |
1987-01-05 |
Fujisawa Pharmaceutical Co |
Anti-tumor agent container fr.900216 substance or its pharmaceutically acceptable salts thereof
|
|
EP0164049B1
(en)
*
|
1984-06-04 |
1990-12-12 |
Merck & Co. Inc. |
Process for preparing hmg-coa reductase inhibtors with a 3,5-dihydroxypentanoate subunit
|
|
US4611068A
(en)
*
|
1984-11-19 |
1986-09-09 |
Merck Frosst Canada, Inc. |
Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein
|
|
EP0204287A3
(en)
*
|
1985-06-04 |
1987-07-01 |
Merck & Co. Inc. |
Process for the preparation of hmg-coa reductase inhibitors with a 3,5-dihydroxypentanoate subunit
|
|
USRE33033E
(en)
*
|
1985-07-05 |
1989-08-22 |
Merck & Co., Inc. |
Process for the preparation of HMG-CoA reductase inhibitors intermediates
|
|
US4611081A
(en)
*
|
1985-07-05 |
1986-09-09 |
Merck & Co., Inc. |
Process for the preparation of HMG-CoA reductase inhibitors intermediates
|
|
US4668699A
(en)
*
|
1985-08-05 |
1987-05-26 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
DE3682557D1
(de)
*
|
1985-09-13 |
1992-01-02 |
Sankyo Co |
Hydroxy-ml-236b-derivate, deren herstellung und anwendung.
|
|
US5272174A
(en)
*
|
1985-09-13 |
1993-12-21 |
Sankyo Company, Limited |
Hydroxy-ML-236B derivatives, their preparation and use
|
|
JPH0633312B2
(ja)
*
|
1986-05-02 |
1994-05-02 |
大正製薬株式会社 |
14−ハイドロキシエリスロマイシン誘導体およびその製造方法
|
|
US4766145A
(en)
*
|
1986-05-05 |
1988-08-23 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
EP0245004A3
(en)
*
|
1986-05-05 |
1989-07-26 |
Merck & Co. Inc. |
Antihypercholesterolemic compounds
|
|
EP0245990A3
(en)
*
|
1986-05-05 |
1989-07-19 |
Merck & Co. Inc. |
Antihypercholesterolemic compounds
|
|
EP0245003A3
(en)
*
|
1986-05-05 |
1989-07-19 |
Merck & Co. Inc. |
Antihypercholesterolemic compounds
|
|
US4864038A
(en)
*
|
1986-05-05 |
1989-09-05 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4847306A
(en)
*
|
1986-05-05 |
1989-07-11 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4937264A
(en)
*
|
1986-05-05 |
1990-06-26 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4771071A
(en)
*
|
1986-05-05 |
1988-09-13 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4661483A
(en)
*
|
1986-05-05 |
1987-04-28 |
Merck & Co., Inc. |
Antihypercholesterolemic lactone compounds, compositions and use
|
|
US4940727A
(en)
*
|
1986-06-23 |
1990-07-10 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
US5116870A
(en)
*
|
1986-06-23 |
1992-05-26 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
|
USRE36481E
(en)
*
|
1986-06-23 |
2000-01-04 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
|
AU1422388A
(en)
*
|
1987-01-27 |
1988-08-10 |
Warner-Lambert Company |
Lipid regulating compositions
|
|
US4833258A
(en)
*
|
1987-02-17 |
1989-05-23 |
Merck & Co., Inc. |
Intermediates useful in the preparation of HMG-COA reductase inhibitors
|
|
EP0306263B1
(en)
*
|
1987-09-02 |
1992-03-18 |
Merck & Co. Inc. |
Novel hmg-coa reductase inhibitors
|
|
US4997848A
(en)
|
1987-10-27 |
1991-03-05 |
Sankyo Company, Limited |
Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
|
|
US4857547A
(en)
*
|
1988-01-07 |
1989-08-15 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
US5021453A
(en)
*
|
1988-03-02 |
1991-06-04 |
Merck & Co., Inc. |
3-keto HMG-CoA reductase inhibitors
|
|
US5155229A
(en)
*
|
1988-03-21 |
1992-10-13 |
E. R. Squibb & Sons, Inc. |
Derivatives of pravastatin and method of making the same
|
|
US5047549A
(en)
*
|
1988-03-21 |
1991-09-10 |
E. R. Squibb & Sons, Inc. |
Derivatives of pravastatin for inhibiting cholesterol biosynthesis
|
|
US4857522A
(en)
*
|
1988-03-21 |
1989-08-15 |
E. R. Squibb & Sons, Inc. |
Derivatives of pravastatin for inhibiting cholesterol biosynthesis
|
|
US5030447A
(en)
*
|
1988-03-31 |
1991-07-09 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions having good stability
|
|
US5180589A
(en)
*
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
|
US4997755A
(en)
*
|
1988-04-15 |
1991-03-05 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors produced by Nocardia sp. (MA 6455)
|
|
US4963538A
(en)
*
|
1988-06-29 |
1990-10-16 |
Merck & Co., Inc. |
5-oxygenated HMG-CoA reductase inhibitors
|
|
US5075327A
(en)
*
|
1988-08-10 |
1991-12-24 |
Hoffmann-La Roche Inc. |
Antipsoriatic agents
|
|
US5021451A
(en)
*
|
1988-11-14 |
1991-06-04 |
Hoffman-La Roche Inc. |
Method for inhibiting hyperproliferative diseases
|
|
US5073568A
(en)
*
|
1988-11-14 |
1991-12-17 |
Hoffmann-La Roche Inc. |
Antipsoriatic agents
|
|
US5200549A
(en)
*
|
1988-11-14 |
1993-04-06 |
Hoffman-La Roche Inc. |
Antipsoriatic agents
|
|
US5376383A
(en)
*
|
1988-11-21 |
1994-12-27 |
Merck & Co., Inc. |
Method for enhancing the lowering of plasma-cholesterol levels
|
|
US5260305A
(en)
*
|
1988-12-12 |
1993-11-09 |
E. R. Squibb & Sons, Inc. |
Combination of pravastatin and nicotinic acid or related acid and method for lowering serum cholesterol using such combination
|
|
JP2763782B2
(ja)
*
|
1989-02-14 |
1998-06-11 |
旭電化工業株式会社 |
メバロン酸の製造方法
|
|
US5166364A
(en)
*
|
1989-02-27 |
1992-11-24 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
|
CA2016467A1
(en)
|
1989-06-05 |
1990-12-05 |
Martin Eisman |
Method for treating peripheral atherosclerotic disease employing an hmg coa reductase inhibitor and/or a squalene synthetase inhibitor
|
|
US5001148A
(en)
*
|
1989-06-07 |
1991-03-19 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
|
US4970231A
(en)
*
|
1989-06-09 |
1990-11-13 |
Merck & Co., Inc. |
4-substituted HMG-CoA reductase inhibitors
|
|
US5010105A
(en)
*
|
1989-06-09 |
1991-04-23 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US5041562A
(en)
*
|
1989-06-09 |
1991-08-20 |
Merck & Co., Inc. |
3-keto HMG-CoA reductase inhibitors
|
|
US5102911A
(en)
*
|
1989-06-09 |
1992-04-07 |
Merck & Co, Inc. |
4-Substituted HMG-CoA reductase inhibitors
|
|
US4937259A
(en)
*
|
1989-06-09 |
1990-06-26 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US5001241A
(en)
*
|
1989-06-09 |
1991-03-19 |
Merck & Co., Inc. |
3-KETO HMG-CoA reductase inhibitors
|
|
US4965200A
(en)
*
|
1989-06-23 |
1990-10-23 |
Merck & Co., Inc. |
Process for the preparation of 3-keto, 5-hydroxy simvastatin analogs
|
|
US4997849A
(en)
*
|
1989-06-23 |
1991-03-05 |
Merck & Co., Inc. |
Microbial transformation of simvastatin
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
US5316765A
(en)
*
|
1989-09-07 |
1994-05-31 |
Karl Folkers Foundation For Biomedical And Clinical Research |
Use of coenzyme Q10 in combination with HMG-CoA reductase inhibitor therapies
|
|
US5212296A
(en)
*
|
1989-09-11 |
1993-05-18 |
E. I. Du Pont De Nemours And Company |
Expression of herbicide metabolizing cytochromes
|
|
US5173487A
(en)
*
|
1989-11-13 |
1992-12-22 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
|
US5177104A
(en)
*
|
1990-04-03 |
1993-01-05 |
E. R. Squibb & Sons, Inc. |
6-α-hydroxy derivatives of mevinic acids
|
|
GB9007738D0
(en)
*
|
1990-04-05 |
1990-06-06 |
British Bio Technology |
Compounds
|
|
US5089523A
(en)
*
|
1990-05-11 |
1992-02-18 |
E. R. Squibb & Sons, Inc. |
Fluorinated derivatives of mevinic acids
|
|
US6630502B2
(en)
|
1990-05-15 |
2003-10-07 |
E.R. Squibb & Sons, Inc. |
Method for preventing, stabilizing or causing regression of atherosclerosis employing a combination of a cholesterol lowering drug and an ace inhibitor
|
|
US5140012A
(en)
*
|
1990-05-31 |
1992-08-18 |
E. R. Squibb & Sons, Inc. |
Method for preventing onset of restenosis after angioplasty employing pravastatin
|
|
US5622985A
(en)
*
|
1990-06-11 |
1997-04-22 |
Bristol-Myers Squibb Company |
Method for preventing a second heart attack employing an HMG CoA reductase inhibitor
|
|
US5264455A
(en)
*
|
1990-07-06 |
1993-11-23 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
|
US5223415A
(en)
*
|
1990-10-15 |
1993-06-29 |
Merck & Co., Inc. |
Biosynthetic production of 7-[1',2',6',7',8',8a'(R)-hexahydro-2'(S),6'(R)-dimethyl-8'(S)-hydroxy-1'(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid)
|
|
IE75349B1
(en)
*
|
1991-03-07 |
1997-08-27 |
Lonza Ag |
A process for the terminal hydroxylation of ethyl groups on aromatic 5- or 6-membered heterocyclic compounds
|
|
US5225202A
(en)
*
|
1991-09-30 |
1993-07-06 |
E. R. Squibb & Sons, Inc. |
Enteric coated pharmaceutical compositions
|
|
US5286746A
(en)
*
|
1991-12-20 |
1994-02-15 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
|
US5620876A
(en)
*
|
1992-04-29 |
1997-04-15 |
E. R. Squibb & Sons, Inc. |
Enzymatic hydrolysis and esterification processes for the preparation of HMG-CoA reductase inhibitors and intermediates thereof
|
|
FI932188L
(fi)
|
1992-05-15 |
1993-11-16 |
Sankyo Co |
Oktahydronaftalenoximderivat foer inhibering av kolesterolbiosyntesen, deras framstaellning och anvaendning
|
|
US5369123A
(en)
*
|
1992-10-09 |
1994-11-29 |
E. R. Squibb & Sons, Inc. |
Nitrogen-substituted mevinic acid derivatives useful as HMG-CoA reductase inhibitors
|
|
NZ250609A
(en)
*
|
1992-12-28 |
1995-07-26 |
Sankyo Co |
Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments
|
|
IL108432A
(en)
*
|
1993-01-29 |
1997-09-30 |
Sankyo Co |
DERIVATIVES OF 3, 5-DIHYDROXY-7- £1, 2, 6, 7, 8, 8a-HEXAHYDRO-2- METHYL-8- (SUBSTITUTED ALKANOYLOXY)-1-NAPHTHYL| HEPTANOIC ACID AND THEIR LACTONES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
|
|
FR2709126B1
(fr)
*
|
1993-08-18 |
1995-09-29 |
Adir |
Nouveaux dérivés de naphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
|
|
US6043064A
(en)
*
|
1993-10-22 |
2000-03-28 |
Bristol-Myers Squibb Company |
Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof
|
|
JPH09504436A
(ja)
|
1993-11-02 |
1997-05-06 |
メルク エンド カンパニー インコーポレーテッド |
トリオールポリケチドシンターゼをコードするdna
|
|
AU1095695A
(en)
*
|
1993-11-09 |
1995-05-29 |
Brigham And Women's Hospital |
Hmg-coa reductase inhibitors in the normalization of vascular endothelial dysfunction
|
|
US6369103B1
(en)
*
|
1994-01-18 |
2002-04-09 |
Bristol-Myers Squibb Company |
Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor
|
|
US5681278A
(en)
*
|
1994-06-23 |
1997-10-28 |
Cormedics Corp. |
Coronary vasculature treatment method
|
|
US6262277B1
(en)
*
|
1994-09-13 |
2001-07-17 |
G.D. Searle And Company |
Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
|
US6268392B1
(en)
|
1994-09-13 |
2001-07-31 |
G. D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
|
|
US6642268B2
(en)
|
1994-09-13 |
2003-11-04 |
G.D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
|
|
US5942423A
(en)
*
|
1995-06-07 |
1999-08-24 |
Massachusetts Institute Of Technology |
Conversion of compactin to pravastatin by actinomadura
|
|
US5616595A
(en)
*
|
1995-06-07 |
1997-04-01 |
Abbott Laboratories |
Process for recovering water insoluble compounds from a fermentation broth
|
|
US5900433A
(en)
*
|
1995-06-23 |
1999-05-04 |
Cormedics Corp. |
Vascular treatment method and apparatus
|
|
NO318765B1
(no)
*
|
1995-07-03 |
2005-05-02 |
Sankyo Co |
Anvendelse av en HMG-CoA reduktaseinhibitor og en insulinsensibilisator til fremstilling av et medikament for forebyggelse eller behandling av arteriosklerose eller xantom, samt pakket farmasoytisk preparat som omfatter de to midlene i separate porsjoner.
|
|
KR100186758B1
(ko)
*
|
1996-08-09 |
1999-04-01 |
영진약품공업 주식회사 |
프라바스타틴(pravastatin)전구체의제조방법
|
|
WO1998031366A1
(en)
*
|
1997-01-17 |
1998-07-23 |
Bristol-Myers Squibb Company |
Method for treating atherosclerosis with an mpt inhibitor and cholesterol lowering drugs
|
|
US6066653A
(en)
*
|
1997-01-17 |
2000-05-23 |
Bristol-Myers Squibb Co. |
Method of treating acid lipase deficiency diseases with an MTP inhibitor and cholesterol lowering drugs
|
|
KR100210482B1
(ko)
*
|
1997-04-10 |
1999-07-15 |
김종인 |
스트렙토마이세스엑스포리아투스(streptomycesexfoliatus)yj-118과이를이용한프라바스타틴나트륨의제조방법
|
|
EP0877089A1
(en)
|
1997-05-07 |
1998-11-11 |
Gist-Brocades B.V. |
HMG-CoA reductase inhibitor preparation process
|
|
US20010006644A1
(en)
|
1997-07-31 |
2001-07-05 |
David J. Bova |
Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
|
|
EP1020530B1
(en)
|
1997-08-07 |
2008-03-12 |
Kyowa Hakko Kogyo Co., Ltd. |
PROCESS FOR THE PREPARATION OF HMG-CoA REDUCTASE INHIBITORS
|
|
EP1015600A1
(en)
*
|
1997-08-22 |
2000-07-05 |
Dsm N.V. |
Statin production by fermentation
|
|
GT199800127A
(es)
*
|
1997-08-29 |
2000-02-01 |
|
Combinaciones terapeuticas.
|
|
US6177121B1
(en)
|
1997-09-29 |
2001-01-23 |
Purdue Research Foundation |
Composition and method for producing low cholesterol eggs
|
|
US6147109A
(en)
*
|
1997-10-14 |
2000-11-14 |
The General Hospital Corporation |
Upregulation of Type III endothelial cell Nitric Oxide Synthase by HMG-CoA reductase inhibitors
|
|
US6083497A
(en)
|
1997-11-05 |
2000-07-04 |
Geltex Pharmaceuticals, Inc. |
Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
|
|
US20080275104A1
(en)
*
|
1997-11-25 |
2008-11-06 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
|
US8679534B2
(en)
*
|
1997-12-12 |
2014-03-25 |
Andrx Labs, Llc |
HMG-CoA reductase inhibitor extended release formulation
|
|
US20040029962A1
(en)
*
|
1997-12-12 |
2004-02-12 |
Chih-Ming Chen |
HMG-COA reductase inhibitor extended release formulation
|
|
US6180597B1
(en)
|
1998-03-19 |
2001-01-30 |
Brigham And Women's Hospital, Inc. |
Upregulation of Type III endothelial cell nitric oxide synthase by rho GTPase function inhibitors
|
|
SI9800144A
(sl)
|
1998-05-21 |
1999-12-31 |
LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. |
Nov biotehnološki postopek pridobivanja 3-hidroksi-ML-236B derivatov poznanih kot M-4 in M-4'
|
|
CA2336201A1
(en)
|
1998-06-24 |
1999-12-29 |
Merck & Co., Inc. |
Compositions and methods for inhibiting bone resorption
|
|
US20030078211A1
(en)
*
|
1998-06-24 |
2003-04-24 |
Merck & Co., Inc. |
Compositions and methods for inhibiting bone resorption
|
|
US6423751B1
(en)
|
1998-07-14 |
2002-07-23 |
The Brigham And Women's Hospital, Inc. |
Upregulation of type III endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization
|
|
US5985907A
(en)
*
|
1998-08-12 |
1999-11-16 |
Health Research, Inc. |
Method for inhibiting growth of methanogens
|
|
SI20070A
(sl)
*
|
1998-09-18 |
2000-04-30 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Nove soli inhibitorjev HMG-CoA reduktaze
|
|
SI20305A
(sl)
*
|
1999-08-06 |
2001-02-28 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Kristali natrijeve soli pravastatina
|
|
US8293277B2
(en)
*
|
1998-10-01 |
2012-10-23 |
Alkermes Pharma Ireland Limited |
Controlled-release nanoparticulate compositions
|
|
US20080213378A1
(en)
*
|
1998-10-01 |
2008-09-04 |
Elan Pharma International, Ltd. |
Nanoparticulate statin formulations and novel statin combinations
|
|
BR9915738A
(pt)
|
1998-11-20 |
2001-10-02 |
Rtp Pharma Inc |
Micropartìculas estabilizadas em fosfolipìdeos dispersìveis
|
|
SI20109A
(sl)
*
|
1998-12-16 |
2000-06-30 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Stabilna farmacevtska formulacija
|
|
US6391583B1
(en)
*
|
1998-12-18 |
2002-05-21 |
Wisconsin Alumni Research Foundation |
Method of producing antihypercholesterolemic agents
|
|
HUP0104745A3
(en)
|
1998-12-23 |
2003-01-28 |
G D Searle Llc Chicago |
Combinations of ileal bile acid transport inhibitors and bile acid sequestring agents for cardiovascular indications
|
|
CZ20012342A3
(cs)
*
|
1998-12-23 |
2001-12-12 |
G. D. Searle Llc |
Kombinace inhibitorů transportu ľlučové kyseliny v ileu a derivátů kyseliny fibrové pro kardiovaskulární indikace
|
|
CA2356422C
(en)
|
1998-12-23 |
2008-09-16 |
G.D. Searle Llc |
Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications
|
|
AU2157500A
(en)
|
1998-12-23 |
2000-07-31 |
G.D. Searle Llc |
Combinations of cholesteryl ester transfer protein inhibitors and bile acid sequestering agents for cardiovascular indications
|
|
JP2002533411A
(ja)
*
|
1998-12-23 |
2002-10-08 |
ジー.ディー.サール エルエルシー |
心臓血管に適用するための組み合わせ
|
|
ES2201827T3
(es)
*
|
1998-12-23 |
2004-03-16 |
G.D. Searle Llc |
Combinaciones de inhibidores de la proteina de transferencia de ester de colesterilo y de derivados de acido fibrico para indicaciones cardiovasculares.
|
|
US6462091B1
(en)
|
1998-12-23 |
2002-10-08 |
G.D. Searle & Co. |
Combinations of cholesteryl ester transfer protein inhibitors and HMG coA reductase inhibitors for cardiovascular indications
|
|
ATE242007T1
(de)
*
|
1998-12-23 |
2003-06-15 |
Searle Llc |
Kombinationen von cholesteryl ester transfer protein inhibitoren und nicotinsäure derivaten für kardiovaskuläre indikationen
|
|
EP1146126B1
(en)
|
1999-01-20 |
2007-04-25 |
Kyowa Hakko Kogyo Co., Ltd. |
PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITORS
|
|
EP1148122B1
(en)
*
|
1999-01-29 |
2009-09-02 |
Kyowa Hakko Bio Co., Ltd. |
PROCESS FOR PRODUCING HMG-CoA REDUCTASE INHIBITOR
|
|
US6682913B1
(en)
*
|
1999-02-03 |
2004-01-27 |
Institute For Drug Research Ltd. |
Microbial process for preparing pravastatin
|
|
US6569461B1
(en)
*
|
1999-03-08 |
2003-05-27 |
Merck & Co., Inc. |
Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors
|
|
HUP9902352A1
(hu)
*
|
1999-07-12 |
2000-09-28 |
Gyógyszerkutató Intézet Kft. |
Eljárás pravasztatin mikrobiológiai előállítására
|
|
SE9903028D0
(sv)
*
|
1999-08-27 |
1999-08-27 |
Astra Ab |
New use
|
|
KR20020040795A
(ko)
*
|
1999-08-30 |
2002-05-30 |
로버트 흐라이탁, 미쉘 베스트 |
심혈관 사고 예방용 레닌-안지오텐신 시스템 억제제의 용도
|
|
MXPA02005283A
(es)
|
1999-11-30 |
2003-10-06 |
Biogal Gyogyszergyar |
Proceso para recuperar compuestos estatina de un caldo de fermentacion.
|
|
US7001919B2
(en)
|
1999-12-14 |
2006-02-21 |
Teva Gyogyszergyar Reszvenytarsasag |
Forms of pravastatin sodium
|
|
IN191580B
(enExample)
|
1999-12-17 |
2003-12-06 |
Ranbaxy Lab Ltd |
|
|
WO2001054728A1
(fr)
*
|
2000-01-28 |
2001-08-02 |
Asahi Kasei Kabushiki Kaisha |
NOUVEAUX REMEDES ET UTILISATION D'UN AGONISTE β3
|
|
ATE429927T1
(de)
*
|
2000-02-04 |
2009-05-15 |
Children S Hospital Res Founda |
Verwendung von lysosomal acid lipase zur behandlung von atherosklerose und ähnlichen krankheiten
|
|
WO2001068637A2
(en)
|
2000-03-10 |
2001-09-20 |
Pharmacia Corporation |
Method for the preparation of tetrahydrobenzothiepines
|
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
|
WO2001068096A2
(en)
*
|
2000-03-10 |
2001-09-20 |
Pharmacia Corporation |
Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
|
|
PT2382970E
(pt)
|
2000-04-10 |
2013-02-18 |
Teva Pharma |
Composições farmacêuticas estáveis que contêm ácidos 7- substituído-3,5-dihidroxiheptanóicos ou ácidos 7-substituído- 3,5-dihidroxiheptenóicos
|
|
AU2001257022B2
(en)
*
|
2000-04-13 |
2005-02-03 |
Mayo Foundation For Medical Education And Research |
Abeta 42 lowering agents
|
|
DE10030375A1
(de)
*
|
2000-06-21 |
2002-01-03 |
Bayer Ag |
Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
|
|
AU2001284413A1
(en)
*
|
2000-08-30 |
2002-03-13 |
Sankyo Company Limited |
Medicinal compositions for preventing or treating heart failure
|
|
JO2654B1
(en)
|
2000-09-04 |
2012-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Multiple aryl caroxa amides are useful as lipid - lowering agents
|
|
US8586094B2
(en)
|
2000-09-20 |
2013-11-19 |
Jagotec Ag |
Coated tablets
|
|
US20050215636A1
(en)
*
|
2000-10-05 |
2005-09-29 |
Vilmos Keri |
Pravastatin sodium substantially free of pravastatin lactone and EPI-pravastatin, and compositions containing same
|
|
US6936731B2
(en)
*
|
2000-10-05 |
2005-08-30 |
TEVA Gyógyszergyár Részvénytársaság |
Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
|
|
MXPA03002963A
(es)
*
|
2000-10-05 |
2005-01-25 |
Biogal Gyogyszergyar |
Pravastatina de sodio sustancialmente libre de pravastatina lactona y epi-pravastatina, y composiciones que la contienen.
|
|
US6534540B2
(en)
|
2000-10-06 |
2003-03-18 |
George Kindness |
Combination and method of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor
|
|
US20030162829A1
(en)
*
|
2000-10-06 |
2003-08-28 |
George Kindness |
Combination of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor
|
|
JP3236282B1
(ja)
*
|
2000-10-16 |
2001-12-10 |
三共株式会社 |
プラバスタチンを精製する方法
|
|
JP2002121172A
(ja)
*
|
2000-10-16 |
2002-04-23 |
Sankyo Co Ltd |
プラバスタチン又はその薬理上許容される塩の精製方法
|
|
US6916849B2
(en)
|
2000-10-23 |
2005-07-12 |
Sankyo Company, Limited |
Compositions for improving lipid content in the blood
|
|
AU2002211005A1
(en)
|
2000-11-07 |
2002-05-21 |
Sankyo Company Limited |
Lipid peroxide-lowering compositions
|
|
JO2409B1
(en)
|
2000-11-21 |
2007-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Second-phenyl carboxy amides are useful as lipid-lowering agents
|
|
US20030232834A1
(en)
*
|
2001-03-08 |
2003-12-18 |
Keller Bradley T |
Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
|
|
BR0208504A
(pt)
*
|
2001-03-27 |
2004-03-09 |
Ranbaxy Lab Ltd |
Composição farmacêutica estável de pravastatina
|
|
JO2390B1
(en)
*
|
2001-04-06 |
2007-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Diphenylcarboxamides act as lipid-lowering agents
|
|
ATE318272T1
(de)
|
2001-04-11 |
2006-03-15 |
Bristol Myers Squibb Co |
Aminosäurekomplexe von c-arylglycosiden zur behandlung von diabetes und verfahren
|
|
AU2002257147B9
(en)
|
2001-04-18 |
2005-08-18 |
Genzyme Corporation |
Methods of treating syndrome X with aliphatic polyamines
|
|
EP1390030A1
(en)
*
|
2001-05-31 |
2004-02-25 |
Cellegy Pharmaceuticals, Inc |
Store operated calcium influx inhibitors and methods of use
|
|
JP2005500307A
(ja)
*
|
2001-06-21 |
2005-01-06 |
アンドルックス ファーマスーティカルズ インコーポレーテッド |
プラバスタチンを含む安定な徐放性薬剤組成物
|
|
US20040180087A1
(en)
*
|
2001-06-21 |
2004-09-16 |
Boyong Li |
Stable controlled release pharmaceutical compositions containing pravastatin
|
|
US20040077625A1
(en)
*
|
2001-07-25 |
2004-04-22 |
Tremont Samuel J. |
Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake
|
|
US20040092565A1
(en)
*
|
2001-07-25 |
2004-05-13 |
George Kindness |
Composition and method of sustaining chemotherapeutic effect while reducing dose of chemotherapeutic agent using cox-2 inhibitor and statin
|
|
KR20040026705A
(ko)
*
|
2001-08-16 |
2004-03-31 |
테바 파마슈티컬 인더스트리즈 리미티드 |
스타틴의 칼슘 염 형태의 제조 방법
|
|
US7189558B2
(en)
*
|
2001-09-27 |
2007-03-13 |
Biocon Limited |
Process for producing pravastatin sodium salt using streptomyces flavidovirens dsm 14455
|
|
KR100414334B1
(ko)
*
|
2001-09-29 |
2004-01-07 |
코바이오텍 (주) |
프라바스타틴 나트륨의 생산 방법
|
|
US7238671B2
(en)
*
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
JP2005514337A
(ja)
*
|
2001-10-18 |
2005-05-19 |
ブリストル−マイヤーズ スクイブ カンパニー |
ヒトグルカゴン様ペプチド−1模倣体、並びに糖尿病および関連疾患の処置におけるその使用
|
|
MXPA04003524A
(es)
*
|
2001-11-02 |
2004-07-23 |
Searle Llc |
Compuestos de benzotiepina monofluorados y difluorados novedosos como inhibidores de transporte de acido biliar co-dependiente de sodio apical (asbt) y captacion de taurocolato.
|
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
|
US6984645B2
(en)
*
|
2001-11-16 |
2006-01-10 |
Bristol-Myers Squibb Company |
Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
|
|
US6831102B2
(en)
*
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
|
JP5082033B2
(ja)
|
2001-12-21 |
2012-11-28 |
エグゼリクシス パテント カンパニー エルエルシー |
Lxrのモジュレーター
|
|
EP1465882B1
(en)
*
|
2001-12-21 |
2011-08-24 |
X-Ceptor Therapeutics, Inc. |
Hetrocyclic modulators of nuclear receptors
|
|
US7482366B2
(en)
|
2001-12-21 |
2009-01-27 |
X-Ceptor Therapeutics, Inc. |
Modulators of LXR
|
|
AU2003207431A1
(en)
|
2002-01-17 |
2003-09-02 |
Pharmacia Corporation |
Novel alkyl/aryl hydroxy or keto thiepines.
|
|
KR100379075B1
(en)
*
|
2002-03-07 |
2003-04-08 |
Jinis Biopharmaceuticals Co |
Method for producing low cholesterol animal food product and food product therefrom
|
|
US7230120B2
(en)
*
|
2002-03-18 |
2007-06-12 |
Biocon |
Amorphous HMG-CoA reductase inhibitors of desired particle size
|
|
US20050089572A1
(en)
*
|
2002-03-22 |
2005-04-28 |
Manoj Kumar |
Controlled release drug delivery system of pravastatin
|
|
JP2005528400A
(ja)
*
|
2002-04-16 |
2005-09-22 |
メルク エンド カムパニー インコーポレーテッド |
チロシンキナーゼ活性を有する塩の固体形態
|
|
AU2003225305A1
(en)
|
2002-05-08 |
2003-11-11 |
Bristol-Myers Squibb Company |
Pyridine-based thyroid receptor ligands
|
|
ES2685697T3
(es)
|
2002-05-09 |
2018-10-10 |
The Brigham And Women's Hospital, Inc. |
1L1RL-1 como un marcador de enfermedades cardiovasculares
|
|
US7672397B2
(en)
*
|
2002-05-14 |
2010-03-02 |
Otmar Irscheid |
Method for producing a transmission signal
|
|
US7057046B2
(en)
*
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
|
CA2488498A1
(en)
*
|
2002-06-10 |
2003-12-18 |
Elan Pharma International Limited |
Nanoparticulate polycosanol formulations and novel polycosanol combinations
|
|
US20050182106A1
(en)
*
|
2002-07-11 |
2005-08-18 |
Sankyo Company, Limited |
Medicinal composition for mitigating blood lipid or lowering blood homocysteine
|
|
AU2003254354A1
(en)
*
|
2002-07-23 |
2004-02-09 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Cholesterol-reducing agent made of dietary fibre and cholesterol-reducing substances
|
|
US20050182036A1
(en)
*
|
2002-08-02 |
2005-08-18 |
Sankyo Company, Limited |
Medicinal composition containing an HMG-CoA reductase inhibitor
|
|
US20050187204A1
(en)
*
|
2002-08-08 |
2005-08-25 |
Sankyo Company, Limited |
Medicinal composition for lowering blood lipid level
|
|
UA79300C2
(en)
*
|
2002-08-12 |
2007-06-11 |
Janssen Pharmaceutica Nv |
N-aryl piperidine substituted biphenylcarboxamides as inhibitors of apolipoprotein b secretion
|
|
EP2298316A1
(en)
|
2002-08-28 |
2011-03-23 |
Harbor BioSciences, Inc. |
Therapeutic treatment methods
|
|
US20060019269A1
(en)
*
|
2002-10-17 |
2006-01-26 |
Decode Genetics, Inc. |
Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
|
|
US20080293750A1
(en)
*
|
2002-10-17 |
2008-11-27 |
Anna Helgadottir |
Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
|
|
WO2004037181A2
(en)
*
|
2002-10-23 |
2004-05-06 |
Bristol-Myers Squibb Company |
Glycinenitrile-based inhibitors of dipeptidyl peptidase iv and methods
|
|
US20080145424A1
(en)
*
|
2002-10-24 |
2008-06-19 |
Enos Phramaceuticals, Inc. |
Sustained release L-arginine formulations and methods of manufacture and use
|
|
WO2005035001A1
(en)
*
|
2003-09-29 |
2005-04-21 |
Enos Pharmaceuticals, Inc. |
Sustained release l-arginine formulations and methods of manufacture and use
|
|
CA2503284A1
(en)
*
|
2002-10-24 |
2004-05-06 |
Enos Pharmaceuticals, Inc. |
Sustained release l-arginine formulations and methods of manufacture and use
|
|
US7098235B2
(en)
*
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
|
US20040110241A1
(en)
*
|
2002-12-06 |
2004-06-10 |
Segal Mark S. |
Materials and methods for monitoring vascular endothelial function
|
|
US20040198800A1
(en)
*
|
2002-12-19 |
2004-10-07 |
Geoffrey Allan |
Lipoxygenase inhibitors as hypolipidemic and anti-hypertensive agents
|
|
JP2006513186A
(ja)
|
2002-12-20 |
2006-04-20 |
ファイザー・プロダクツ・インク |
Cetp阻害剤およびhmg−coaレダクターゼ阻害剤を含む剤形
|
|
CA2510320C
(en)
|
2002-12-20 |
2012-10-09 |
St. James Associates Llc/Faber Research Series |
Coated particles for sustained-release pharmaceutical administration
|
|
US20040132771A1
(en)
*
|
2002-12-20 |
2004-07-08 |
Pfizer Inc |
Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
|
|
DE10261061A1
(de)
*
|
2002-12-24 |
2004-07-15 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Diätetisches Lebensmittel zur positiven Beeinflussung der kardiovaskulären Gesundheit
|
|
DE10261067A1
(de)
*
|
2002-12-24 |
2004-08-05 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Cholesterinsenkendes Mittel, enthaltend eine n-3-Fettsäure
|
|
US20040176425A1
(en)
*
|
2003-01-24 |
2004-09-09 |
Washburn William N. |
Cycloalkyl containing anilide ligands for the thyroid receptor
|
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
|
WO2004071431A2
(en)
*
|
2003-02-05 |
2004-08-26 |
Myriad Genetics, Inc. |
Method and composition for treating neurodegenerative disorders
|
|
EP1452602A1
(en)
*
|
2003-02-25 |
2004-09-01 |
Antibiotic Co., |
Method for production of pravastatin by fermentation
|
|
US7557143B2
(en)
*
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
|
AU2004233693B2
(en)
*
|
2003-04-28 |
2007-07-19 |
Funahashi, Toru |
Adiponectin production enhancer
|
|
EP1618893A4
(en)
*
|
2003-04-28 |
2009-08-12 |
Sankyo Co |
MEANS FOR INCREASING SUGAR CAPACITY
|
|
AR041089A1
(es)
|
2003-05-15 |
2005-05-04 |
Merck & Co Inc |
Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas
|
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
|
KR100470078B1
(ko)
*
|
2003-06-12 |
2005-02-04 |
씨제이 주식회사 |
컴팩틴을 프라바스타틴으로 전환할 수 있는 스트렙토마이세스 종(Streptomyces sp.)CJPV 975652 및 그를 이용한 프라바스타틴의 제조방법
|
|
US7368468B2
(en)
*
|
2003-06-18 |
2008-05-06 |
Teva Pharmaceutical Industries Ltd. |
Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them
|
|
MXPA05013895A
(es)
|
2003-06-18 |
2006-03-09 |
Teva Pharma |
Formas cristalinas de fluvastatina de sodio, procesos para prepararlas, composiciones que las contienen y metodos de usarlas.
|
|
US20050043272A1
(en)
*
|
2003-07-11 |
2005-02-24 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods for hydrophobic drug delivery
|
|
WO2005065069A2
(en)
*
|
2003-07-11 |
2005-07-21 |
Myriad Genetics, Inc. |
Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease
|
|
US20050037063A1
(en)
*
|
2003-07-21 |
2005-02-17 |
Bolton Anthony E. |
Combined therapies
|
|
US6995183B2
(en)
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
CN1839114A
(zh)
|
2003-08-21 |
2006-09-27 |
默克弗罗斯特加拿大有限公司 |
组织蛋白酶半胱氨酸蛋白酶抑制剂
|
|
EP1510208A1
(en)
|
2003-08-22 |
2005-03-02 |
Fournier Laboratories Ireland Limited |
Pharmaceutical composition comprising a combination of metformin and statin
|
|
US7396927B2
(en)
*
|
2003-08-28 |
2008-07-08 |
Teva Pharmaceutical Industries Ltd. |
Process for preparation of rosuvastatin calcium
|
|
RU2358734C2
(ru)
*
|
2003-08-29 |
2009-06-20 |
Кова Ко., Лтд. |
Способ стабилизации бляшки с высоким содержанием липидов и способ профилактики ее разрушения
|
|
US20050053664A1
(en)
*
|
2003-09-08 |
2005-03-10 |
Eliezer Zomer |
Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
|
|
US20050171207A1
(en)
*
|
2003-09-26 |
2005-08-04 |
Myriad Genetics, Incorporated |
Method and composition for combination treatment of neurodegenerative disorders
|
|
US8227434B1
(en)
|
2003-11-04 |
2012-07-24 |
H. Lee Moffitt Cancer Center & Research Institute, Inc. |
Materials and methods for treating oncological disorders
|
|
ATE428411T1
(de)
*
|
2003-11-07 |
2009-05-15 |
Jj Pharma Inc |
Hdl-verstärkende kombinationstherapie-komplexe
|
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
BRPI0416444B8
(pt)
*
|
2003-11-12 |
2021-05-25 |
Chiesi Farm Spa |
composto de ácido borônico heterocíclico, composição farmacêutica, e, combinação farmacêutica compreendendo o mesmo
|
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
JPWO2005046706A1
(ja)
*
|
2003-11-17 |
2007-05-31 |
株式会社東洋新薬 |
松樹皮抽出物を含む脂質代謝改善剤
|
|
RU2422450C2
(ru)
|
2003-11-19 |
2011-06-27 |
Метабазис Терапеутикс, Инк. |
Новые фосфорсодержащие тиромиметики
|
|
US7777034B2
(en)
*
|
2003-11-24 |
2010-08-17 |
Teva Pharmaceutical Industries Ltd. |
Crystalline ammonium salts of rosuvastatin
|
|
ATE412409T1
(de)
*
|
2003-11-24 |
2008-11-15 |
Teva Gyogyszergyar Zartkoeruee |
Verfahren zur reinigung von pravastatin
|
|
US8415364B2
(en)
*
|
2003-11-26 |
2013-04-09 |
Duke University |
Method of preventing or treating glaucoma
|
|
CN1277826C
(zh)
*
|
2003-12-01 |
2006-10-04 |
叶红平 |
辉伐他汀及其合成方法和以辉伐他汀为原料药的制剂
|
|
PT1689723E
(pt)
*
|
2003-12-02 |
2011-07-06 |
Teva Pharma |
Padrão referência para a caracterização de rosuvastatina
|
|
KR20060118557A
(ko)
*
|
2003-12-17 |
2006-11-23 |
다이닛본 스미토모 세이야꾸 가부시끼가이샤 |
의약 조성물 및 조합물
|
|
WO2005062824A2
(en)
|
2003-12-23 |
2005-07-14 |
Merck & Co., Inc. |
Anti-hypercholesterolemic compounds
|
|
US20070179166A1
(en)
*
|
2003-12-24 |
2007-08-02 |
Valerie Niddam-Hildesheim |
Process for preparation of statins with high syn to anti ratio
|
|
US20050159615A1
(en)
*
|
2003-12-24 |
2005-07-21 |
Entire Interest. |
Process for preparation of statins with high syn to anti ratio
|
|
US7851624B2
(en)
*
|
2003-12-24 |
2010-12-14 |
Teva Pharamaceutical Industries Ltd. |
Triol form of rosuvastatin and synthesis of rosuvastatin
|
|
US20070161700A1
(en)
*
|
2004-12-28 |
2007-07-12 |
Kowa Company, Ltd. |
Inhibitor for the formation of y-secretase complex
|
|
US8163797B2
(en)
*
|
2003-12-31 |
2012-04-24 |
Actavis Elizabeth Llc |
Method of treating with stable pravastatin formulation
|
|
TWI252253B
(en)
*
|
2004-01-09 |
2006-04-01 |
Chinese Petroleum Corp |
A novel Pseudonocardia sp RMRC PAH4 and a process for bioconverting compactin into pravastatin using the same
|
|
US20100216863A1
(en)
*
|
2004-01-30 |
2010-08-26 |
Decode Genetics Ehf. |
Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
|
|
US8158362B2
(en)
*
|
2005-03-30 |
2012-04-17 |
Decode Genetics Ehf. |
Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
|
|
EP1563837A1
(en)
*
|
2004-02-03 |
2005-08-17 |
Ferrer Internacional, S.A. |
Hypocholesterolemic compositions comprising a statin and an antiflatulent agent
|
|
US20070078109A1
(en)
*
|
2004-02-13 |
2007-04-05 |
David Platt |
Compositions and methods used to treat acne and candida
|
|
US8309574B2
(en)
*
|
2004-02-25 |
2012-11-13 |
Kowa Company, Ltd. |
Nuclear transfer promoter for Rac protein and method of screening the same
|
|
EP1719525B1
(en)
|
2004-02-25 |
2014-12-10 |
Kowa Company, Ltd. |
Nuclear transfer promoter for cdc42 protein and method of screening the same
|
|
HRP20130115T4
(hr)
|
2004-03-05 |
2016-04-22 |
The Trustees Of The University Of Pennsylvania |
Postupci liječenja poremećaja ili bolesti povezanih sa hiperlipidemijom i hiperkolesterolemijom uz minimizaciju sporednih efekata
|
|
US20060211752A1
(en)
|
2004-03-16 |
2006-09-21 |
Kohn Leonard D |
Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
|
|
EP1734819A1
(en)
*
|
2004-03-19 |
2006-12-27 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods for targeting metastatic tumors using multivalent ligand-linked carbohydrate polymers
|
|
US7777056B2
(en)
*
|
2004-03-30 |
2010-08-17 |
Lupin Ltd. |
Method for manufacture of 4-hydroxy pyran-2-one derivatives
|
|
EP1731147A4
(en)
*
|
2004-03-31 |
2010-06-30 |
Kowa Co |
TOPICAL PREPARATION
|
|
KR100598326B1
(ko)
|
2004-04-10 |
2006-07-10 |
한미약품 주식회사 |
HMG-CoA 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법
|
|
WO2006001877A2
(en)
*
|
2004-04-13 |
2006-01-05 |
Myriad Genetics, Inc. |
Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
|
|
WO2005115380A2
(en)
*
|
2004-05-27 |
2005-12-08 |
Dexcel Pharma Technologies Ltd |
Localized controlled absorption of statins in the gastrointestinal tract for achieving high blood levels of statins
|
|
US7803838B2
(en)
*
|
2004-06-04 |
2010-09-28 |
Forest Laboratories Holdings Limited |
Compositions comprising nebivolol
|
|
UA87854C2
(en)
|
2004-06-07 |
2009-08-25 |
Мерк Энд Ко., Инк. |
N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
|
|
TW200611704A
(en)
*
|
2004-07-02 |
2006-04-16 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
|
US7145040B2
(en)
*
|
2004-07-02 |
2006-12-05 |
Bristol-Myers Squibb Co. |
Process for the preparation of amino acids useful in the preparation of peptide receptor modulators
|
|
US7534763B2
(en)
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
|
US7786163B2
(en)
*
|
2004-07-12 |
2010-08-31 |
Forest Laboratories Holdings Limited (BM) |
Constrained cyano compounds
|
|
EP1673351A1
(en)
*
|
2004-07-13 |
2006-06-28 |
Teva Pharmaceutical Industries Ltd. |
A process for the preparation of rosuvastatin involving a tempo-mediated oxidation step
|
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
|
US20110217412A1
(en)
*
|
2004-07-30 |
2011-09-08 |
Jinis Biopharmaceuticals Co. |
Cholesterol lowering supplement and low cholesterol egg produced by using the same
|
|
KR100637762B1
(ko)
*
|
2004-07-30 |
2006-10-23 |
주식회사 지니스 |
저콜레스테롤 란을 생산하기 위한 가금류용 사료첨가제 및 이를 이용한 저콜레스테롤 란의 생산방법
|
|
US20080286251A1
(en)
*
|
2004-08-02 |
2008-11-20 |
Propharmaceuticals, Inc. |
Compositions and Methods for the Enhancement of Chemotherapy with Microbial Cytotoxins
|
|
AU2005271407A1
(en)
*
|
2004-08-06 |
2006-02-16 |
Transform Pharmaceuticals, Inc. |
Novel fenofibrate formulations and related methods of treatment
|
|
US20090042979A1
(en)
*
|
2004-08-06 |
2009-02-12 |
Transform Pharmaceuticals Inc. |
Novel Statin Pharmaceutical Compositions and Related Methods of Treatment
|
|
WO2006017698A2
(en)
*
|
2004-08-06 |
2006-02-16 |
Transform Pharmaceuticals, Inc. |
Novel statin pharmaceutical compositions and related methods of treatment
|
|
CA2618985A1
(en)
*
|
2004-08-11 |
2006-02-23 |
Myriad Genetics, Inc. |
Pharmaceutical composition and method for treating neurodegenerative disorders
|
|
WO2006020850A2
(en)
*
|
2004-08-11 |
2006-02-23 |
Myriad Genetics, Inc. |
Pharmaceutical composition and method for treating neurodegenerative disorders
|
|
WO2006020852A2
(en)
*
|
2004-08-11 |
2006-02-23 |
Myriad Genetics, Inc. |
Pharmaceutical composition and method for treating neurodegenerative disorders
|
|
US20070244107A1
(en)
*
|
2004-08-25 |
2007-10-18 |
Waters M Gerard |
Method of Treating Atherosclerosis, Dyslipidemias and Related Conditions
|
|
US20060058261A1
(en)
*
|
2004-09-15 |
2006-03-16 |
Andre Aube |
Chitin derivatives for hyperlipidemia
|
|
AR051446A1
(es)
*
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
|
EP2343553A1
(en)
|
2004-10-06 |
2011-07-13 |
The Brigham and Women's Hospital |
Relevance of achieved levels of markers of systemic inflammation following treatment
|
|
US7517991B2
(en)
*
|
2004-10-12 |
2009-04-14 |
Bristol-Myers Squibb Company |
N-sulfonylpiperidine cannabinoid receptor 1 antagonists
|
|
TW200619191A
(en)
*
|
2004-10-27 |
2006-06-16 |
Sankyo Co |
Phenyl compounds with more than 2 substitutes
|
|
AU2005305459A1
(en)
*
|
2004-11-22 |
2006-05-26 |
Dexcel Pharma Technologies Ltd. |
Controlled absorption of statins in the intestine
|
|
TWI307360B
(en)
|
2004-12-03 |
2009-03-11 |
Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag |
Process for constructing strain having compactin hydroxylation ability
|
|
KR20070085874A
(ko)
|
2004-12-09 |
2007-08-27 |
머크 앤드 캄파니 인코포레이티드 |
에스트로겐 수용체 조절제
|
|
TW200619204A
(en)
*
|
2004-12-10 |
2006-06-16 |
Kowa Co |
Method for reduction, stabilization and prevention of rupture of lipid rich plaque
|
|
CA2590278A1
(en)
*
|
2004-12-15 |
2006-06-22 |
Solvay Pharmaceuticals Gmbh |
Pharmaceutical compositions comprising nep-inhibitors, inhibitors of the endogenous endothelin producing system and hmg coa reductase inhibitors
|
|
US7589088B2
(en)
*
|
2004-12-29 |
2009-09-15 |
Bristol-Myers Squibb Company |
Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7635699B2
(en)
*
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
AU2006204038A1
(en)
*
|
2005-01-06 |
2006-07-13 |
Merck & Co., Inc. |
Drug combination therapy and pharmaceutical compositions for treating inflammatory disorders
|
|
US7368458B2
(en)
*
|
2005-01-12 |
2008-05-06 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
US7314882B2
(en)
*
|
2005-01-12 |
2008-01-01 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
US7220859B2
(en)
|
2005-01-12 |
2007-05-22 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
WO2006078697A1
(en)
*
|
2005-01-18 |
2006-07-27 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
RU2433823C2
(ru)
*
|
2005-01-31 |
2011-11-20 |
Милан Лэборетериз, Инк. |
Фармацевтическая композиция, содержащая гидроксилированный небиволол
|
|
JP2007533663A
(ja)
*
|
2005-02-09 |
2007-11-22 |
テバ ジョジセルジャール ザ−トケルエン ムケド レ−スベニュタ−ルシャシャ−グ |
プラバスタチンナトリウムの製造方法
|
|
ES2319461T3
(es)
*
|
2005-02-10 |
2009-05-07 |
Bristol-Myers Squibb Company |
Dihidroquinazolinonas como moduladores de 5ht.
|
|
WO2006091770A2
(en)
*
|
2005-02-22 |
2006-08-31 |
Teva Pharmaceutical Industries Ltd. |
Rosuvastatin and salts thereof free of rosuvastatin alkylether and a process for the preparation thereof
|
|
US20070167625A1
(en)
*
|
2005-02-22 |
2007-07-19 |
Anna Balanov |
Preparation of rosuvastatin
|
|
US20070037979A1
(en)
*
|
2005-02-22 |
2007-02-15 |
Valerie Niddam-Hildesheim |
Preparation of rosuvastatin
|
|
US20070293535A1
(en)
*
|
2005-02-24 |
2007-12-20 |
Kowa Company, Ltd. |
Nuclear Transfer Promoter for Ddc42 Protein and Method of Screening the Dame
|
|
CN104188952A
(zh)
|
2005-03-02 |
2014-12-10 |
默沙东公司 |
抑制组织蛋白酶k的组合物
|
|
CA2603105A1
(en)
*
|
2005-03-28 |
2006-10-05 |
Dexcel Pharma Technologies Ltd. |
Controlled absorption of statins in the intestine
|
|
WO2006113261A2
(en)
|
2005-04-14 |
2006-10-26 |
Bristol-Myers Squibb Company |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type i
|
|
WO2006123182A2
(en)
|
2005-05-17 |
2006-11-23 |
Merck Sharp & Dohme Limited |
Cyclohexyl sulphones for treatment of cancer
|
|
US7521557B2
(en)
|
2005-05-20 |
2009-04-21 |
Bristol-Myers Squibb Company |
Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7825139B2
(en)
*
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
WO2006125304A1
(en)
*
|
2005-05-25 |
2006-11-30 |
Liponex, Inc. |
Pharmaceutical compositions for treating or preventing coronary artery disease
|
|
TW200716679A
(en)
*
|
2005-05-26 |
2007-05-01 |
Bristol Myers Squibb Co |
N-terminally modified GLP-1 receptor modulators
|
|
NZ563759A
(en)
|
2005-05-31 |
2010-06-25 |
Mylan Lab Inc |
Compositions comprising nebivolol, a hydralazine compound and an isosorbide nitrate
|
|
US7629342B2
(en)
*
|
2005-06-17 |
2009-12-08 |
Bristol-Myers Squibb Company |
Azabicyclic heterocycles as cannabinoid receptor modulators
|
|
US7632837B2
(en)
*
|
2005-06-17 |
2009-12-15 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid-1 receptor modulators
|
|
US7452892B2
(en)
*
|
2005-06-17 |
2008-11-18 |
Bristol-Myers Squibb Company |
Triazolopyrimidine cannabinoid receptor 1 antagonists
|
|
US7572808B2
(en)
*
|
2005-06-17 |
2009-08-11 |
Bristol-Myers Squibb Company |
Triazolopyridine cannabinoid receptor 1 antagonists
|
|
US7317012B2
(en)
*
|
2005-06-17 |
2008-01-08 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoind-1 receptor modulators
|
|
US20060287342A1
(en)
*
|
2005-06-17 |
2006-12-21 |
Mikkilineni Amarendra B |
Triazolopyrimidine heterocycles as cannabinoid receptor modulators
|
|
JP5237799B2
(ja)
|
2005-06-27 |
2013-07-17 |
エグゼリクシス パテント カンパニー エルエルシー |
ピラゾールベースのlxrモジュレーター
|
|
US20070015832A1
(en)
*
|
2005-07-14 |
2007-01-18 |
Myriad Genetics, Incorporated |
Methods of treating overactive bladder and urinary incontinence
|
|
JP2009502959A
(ja)
*
|
2005-07-28 |
2009-01-29 |
ブリストル−マイヤーズ スクイブ カンパニー |
セロトニン受容体アゴニストおよびアンタゴニストとしての置換テトラヒドロ−1h−ピリド[4,3,b]インドール
|
|
AU2006278444A1
(en)
*
|
2005-08-04 |
2007-02-15 |
Transform Pharmaceuticals, Inc. |
Novel formulations comprising fenofibrate and a statin, and related methods of treatment
|
|
KR20070062996A
(ko)
*
|
2005-08-16 |
2007-06-18 |
테바 파마슈티컬 인더스트리즈 리미티드 |
결정성 로수바스타틴 중간체
|
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
|
TWI387592B
(zh)
*
|
2005-08-30 |
2013-03-01 |
Novartis Ag |
經取代之苯并咪唑及其作為與腫瘤形成相關激酶之抑制劑之方法
|
|
WO2007030302A2
(en)
*
|
2005-09-01 |
2007-03-15 |
Prescient Medical, Inc. |
Drugs coated on a device to treat vulnerable plaque
|
|
WO2007030375A2
(en)
*
|
2005-09-08 |
2007-03-15 |
Children's Hospital Medical Center |
Lysosomal acid lipase therapy for nafld and related diseases
|
|
US20080139457A1
(en)
*
|
2005-09-16 |
2008-06-12 |
Virginia Commonwealth University |
Therapeutic compositions comprising chorionic gonadotropins and HMG CoA reductase inhibitors
|
|
US8119358B2
(en)
|
2005-10-11 |
2012-02-21 |
Tethys Bioscience, Inc. |
Diabetes-related biomarkers and methods of use thereof
|
|
DE102005049293A1
(de)
*
|
2005-10-15 |
2007-04-26 |
Bayer Healthcare Ag |
Kombinationspräparate von Salzen oder o-Acetylsalicylsäure
|
|
EP1951224A2
(en)
*
|
2005-10-18 |
2008-08-06 |
Aegerion Pharmaceuticals |
Methods for treating disorders associated with hyperlipidemia in a mammal
|
|
US7741317B2
(en)
|
2005-10-21 |
2010-06-22 |
Bristol-Myers Squibb Company |
LXR modulators
|
|
AR056155A1
(es)
|
2005-10-26 |
2007-09-19 |
Bristol Myers Squibb Co |
Antagonistas del receptor 1 de la hormona de concentracion de melanina no basica
|
|
EP2487154B1
(en)
|
2005-10-31 |
2013-10-16 |
Bristol-Myers Squibb Company |
Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US8440695B2
(en)
*
|
2005-11-09 |
2013-05-14 |
St Jude Children's Research Hospital |
Use of chloroquine to treat metabolic syndrome
|
|
US7888376B2
(en)
|
2005-11-23 |
2011-02-15 |
Bristol-Myers Squibb Company |
Heterocyclic CETP inhibitors
|
|
JP5631534B2
(ja)
*
|
2005-11-29 |
2014-11-26 |
協和発酵バイオ株式会社 |
新規蛋白質および該蛋白質をコードするdna
|
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
|
EP1981849A1
(en)
*
|
2005-12-29 |
2008-10-22 |
LEK Pharmaceuticals D.D. |
Heterocyclic compounds
|
|
WO2007082264A2
(en)
*
|
2006-01-11 |
2007-07-19 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
|
US7553836B2
(en)
*
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
CA2569776A1
(en)
*
|
2006-02-17 |
2007-08-17 |
Kos Life Sciences, Inc. |
Low flush niacin formulation
|
|
US20090069275A1
(en)
*
|
2006-02-17 |
2009-03-12 |
Rocca Jose G |
Low flush niacin formulation
|
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
|
CA2649288C
(en)
|
2006-04-19 |
2015-11-24 |
Novartis Ag |
6-o-substituted benzoxazole and benzothiazole compounds and methods of inhibiting csf-1r signaling
|
|
JP2009534423A
(ja)
|
2006-04-20 |
2009-09-24 |
アムジェン インコーポレイテッド |
Glp−1化合物
|
|
US20070254897A1
(en)
*
|
2006-04-28 |
2007-11-01 |
Resolvyx Pharmaceuticals, Inc. |
Compositions and methods for the treatment of cardiovascular disease
|
|
US20070269503A1
(en)
*
|
2006-05-16 |
2007-11-22 |
James Walter Burgess |
Combinations of HMG CoA reductase inhibitors and negatively charged phospholipids and uses thereof
|
|
EP2021014A1
(en)
*
|
2006-05-26 |
2009-02-11 |
Brystol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
EP2030025A2
(en)
*
|
2006-06-07 |
2009-03-04 |
Tethys Bioscience, Inc. |
Markers associated with arteriovascular events and methods of use thereof
|
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
|
US20080044326A1
(en)
*
|
2006-07-04 |
2008-02-21 |
Esencia Co., Ltd. |
Sterilizer for baby products
|
|
RS53084B
(sr)
|
2006-07-05 |
2014-06-30 |
Takeda Gmbh |
Kombinacija inhibitora hmg-coa reduktaze rosuvastatina sa inhibitorom fosfodiesteraze 4, kao što je roflumilast, roflumilast-n-oksid za lečenje inflamatornih plućnih obolenja
|
|
EP2046119A2
(en)
*
|
2006-07-07 |
2009-04-15 |
Myriad Genetics, Inc. |
Treatment of psychiatric disorders
|
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
WO2008026702A1
(fr)
|
2006-08-30 |
2008-03-06 |
Kyushu University, National University Corporation |
Composition pharmaceutique contenant une nanoparticule de statine encapsulée
|
|
US8173629B2
(en)
|
2006-09-22 |
2012-05-08 |
Merck Sharp & Dohme Corp. |
Method of treatment using fatty acid synthesis inhibitors
|
|
EP2079448A2
(en)
*
|
2006-10-10 |
2009-07-22 |
Dexcel Pharma Technologies Ltd. |
Improved release of statins in the intestine
|
|
US20080118572A1
(en)
*
|
2006-10-10 |
2008-05-22 |
Harold Richard Hellstrom |
Methods and compositions for reducing the risk of adverse cardiovascular events associated with the administration of artificial blood
|
|
WO2008057862A2
(en)
|
2006-11-01 |
2008-05-15 |
Bristol-Myers Squibb Company |
MODULATORS OF GLUCOCORTICOID RECEPTOR, AP-1, AND/OR NF-ϰB ACTIVITY AND USE THEREOF
|
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
|
AU2007338625A1
(en)
*
|
2006-12-21 |
2008-07-03 |
Aegerion Pharmaceuticals, Inc. |
Methods for treating obesity with a combination comprising a MTP inhibitor and a cholesterol absorption inhibitor
|
|
EP2336120B1
(en)
|
2007-01-10 |
2014-07-16 |
MSD Italia S.r.l. |
Combinations containing amide substituted indazoles as poly(adp-ribose)polymerase (parp) inhibitors
|
|
CA2679403A1
(en)
*
|
2007-03-01 |
2008-09-04 |
Concourse Health Sciences Llc |
Isomers of inositol niacinate and uses thereof
|
|
JP5330274B2
(ja)
|
2007-03-01 |
2013-10-30 |
ノバルティス アーゲー |
Pimキナーゼ阻害剤およびその使用方法
|
|
CL2008000684A1
(es)
|
2007-03-09 |
2008-08-01 |
Indigene Pharmaceuticals Inc |
Composicion farmaceutica que comprende metformina r-(+) lipoato y un inhibidor de reductasa hmg-coa; formulacion de dosis unitaria; y uso en el tratamiento de una complicacion diabetica.
|
|
US20080227846A1
(en)
*
|
2007-03-13 |
2008-09-18 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
|
PE20090185A1
(es)
|
2007-03-22 |
2009-02-28 |
Bristol Myers Squibb Co |
Formulaciones farmaceuticas que contienen un inhibidor sglt2
|
|
TWI407955B
(zh)
|
2007-03-29 |
2013-09-11 |
Kowa Co |
高脂血症之預防及/或治療劑
|
|
US20080249141A1
(en)
*
|
2007-04-06 |
2008-10-09 |
Palepu Nageswara R |
Co-therapy with and combinations of statins and 1,4-dihydropyridine-3,5-dicarboxydiesters
|
|
WO2008124122A1
(en)
*
|
2007-04-09 |
2008-10-16 |
Scidose, Llc |
Combinations of statins and anti-obesity agent and glitazones
|
|
CN101795684A
(zh)
*
|
2007-04-09 |
2010-08-04 |
赛多斯有限责任公司 |
他汀类化合物与抗肥胖药的组合
|
|
US8546394B2
(en)
|
2007-04-17 |
2013-10-01 |
Bristol-Myers Squibb Company |
Substituted [1,2,4]triazolo[4,3-A]pyrazine 11-beta-hydroxysteroid dehydrogenase inhibitors
|
|
CN102317786A
(zh)
|
2007-04-18 |
2012-01-11 |
特提斯生物科学公司 |
糖尿病相关性生物学标记物及其使用方法
|
|
PE20090696A1
(es)
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
|
WO2008139703A1
(ja)
|
2007-04-27 |
2008-11-20 |
Kyushu University, National University Corporation |
肺疾患治療薬
|
|
CN101754972A
(zh)
*
|
2007-05-18 |
2010-06-23 |
百时美施贵宝公司 |
Sglt2抑制剂的晶体结构及其制备方法
|
|
US8293769B2
(en)
|
2007-05-21 |
2012-10-23 |
Novartis Ag |
CSF-1R inhibitors, compositions, and methods of use
|
|
AU2008287542C1
(en)
|
2007-06-01 |
2015-01-22 |
The Trustees Of Princeton University |
Treatment of viral infections by modulation of host cell metabolic pathways
|
|
DE102007028407A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
DE102007028320A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
DE102007028406A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
DE102007028319A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
WO2008156721A1
(en)
|
2007-06-20 |
2008-12-24 |
Merck & Co., Inc. |
Diphenyl substituted alkanes
|
|
JP5501227B2
(ja)
|
2007-06-27 |
2014-05-21 |
メルク・シャープ・アンド・ドーム・コーポレーション |
ヒストンデアセチラーゼ阻害剤としての4−カルボキシベンジルアミノ誘導体
|
|
US20090011994A1
(en)
*
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
|
EP2173717B9
(en)
*
|
2007-07-27 |
2013-06-26 |
Bristol-Myers Squibb Company |
Novel glucokinase activators and methods of using same
|
|
US20090076148A1
(en)
*
|
2007-09-14 |
2009-03-19 |
Protia, Llc |
Deuterium-enriched pravastatin
|
|
MX2010003117A
(es)
*
|
2007-09-20 |
2010-04-01 |
Irm Llc |
Compuestos y composiciones como moduladores de la actividad de gpr119.
|
|
JP2011503081A
(ja)
|
2007-11-01 |
2011-01-27 |
ブリストル−マイヤーズ スクイブ カンパニー |
グルココルチコイド受容体、AP−1および/またはNF−κB活性の調節剤として有用な非ステロイド性化合物、並びにその使用
|
|
US20090163452A1
(en)
*
|
2007-12-20 |
2009-06-25 |
Schwartz Janice B |
Compositions and methods for lowering serum cholesterol
|
|
EP2222636B1
(en)
|
2007-12-21 |
2013-04-10 |
Ligand Pharmaceuticals Inc. |
Selective androgen receptor modulators (sarms) and uses thereof
|
|
US20090226516A1
(en)
*
|
2008-03-04 |
2009-09-10 |
Pharma Pass Ii Llc |
Sartan compositions
|
|
US20090226515A1
(en)
*
|
2008-03-04 |
2009-09-10 |
Pharma Pass Ii Llc |
Statin compositions
|
|
EP2288378A4
(en)
*
|
2008-04-16 |
2011-12-14 |
Univ Utah Res Found |
PHARMACOLOGICAL TARGETING OF VEGETABLE ILLNESS
|
|
PE20091928A1
(es)
*
|
2008-05-29 |
2009-12-31 |
Bristol Myers Squibb Co |
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
|
|
ES2330184B1
(es)
|
2008-06-03 |
2010-07-05 |
Neuron Biopharma, S.A. |
Uso de estatinas como anticonvulsivantes, antiepilepticos y neuroprotectores.
|
|
EP2138178A1
(en)
|
2008-06-28 |
2009-12-30 |
Bayer Schering Pharma Aktiengesellschaft |
Oxazolidninones for the treatment fo chronic obstructive pulmonary disease (COPD) and/or asthma
|
|
EP2161024A1
(de)
|
2008-09-05 |
2010-03-10 |
Universitätsklinikum Hamburg-Eppendorf |
Kombinationspräparat zur Behandlung von Krebs
|
|
US9006412B2
(en)
|
2008-10-06 |
2015-04-14 |
Microbiopharm Japan Co., Ltd. |
Expression vector for pseudonocardia autotrophica
|
|
WO2010093601A1
(en)
|
2009-02-10 |
2010-08-19 |
Metabasis Therapeutics, Inc. |
Novel sulfonic acid-containing thyromimetics, and methods for their use
|
|
EA201101231A1
(ru)
|
2009-03-27 |
2012-06-29 |
Бристол-Майерс Сквибб Компани |
Способы предотвращения или снижения риска смертности
|
|
US8691825B2
(en)
|
2009-04-01 |
2014-04-08 |
Merck Sharp & Dohme Corp. |
Inhibitors of AKT activity
|
|
TW201039815A
(en)
|
2009-04-13 |
2010-11-16 |
Resolvyx Pharmaceuticals Inc |
Compositions and methods for the treatment of inflammation
|
|
US8470805B2
(en)
*
|
2009-04-30 |
2013-06-25 |
Kaohsiung Medical University |
Processes for preparing piperazinium salts of KMUP and use thereof
|
|
PE20120797A1
(es)
|
2009-05-28 |
2012-07-08 |
Exelisis Patent Company Llc |
Derivados de 1-[(3'-fluoro-4'-hidroximetil-5'-metilsulfonil)bifenil-4-il]-2-bencil-4-[(1-hidroxi-1-metil)etil]-1h-imidazol como moduladores de lxr
|
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
|
AU2010303780B2
(en)
|
2009-10-09 |
2014-02-20 |
Irm Llc |
Compounds and compositions as modulators of GPR119 activity
|
|
BR112012008849A2
(pt)
|
2009-10-14 |
2015-09-22 |
Schering Corp |
composto, composição farmacêutica, e, uso de um composto
|
|
CN102711738A
(zh)
|
2009-11-13 |
2012-10-03 |
百时美施贵宝公司 |
质量得以减小的二甲双胍制剂
|
|
RS57926B1
(sr)
|
2009-11-13 |
2019-01-31 |
Astrazeneca Ab |
Formulacije tablete sa trenutnim oslobađanjem
|
|
LT2498758T
(lt)
|
2009-11-13 |
2018-11-26 |
Astrazeneca Ab |
Dvisluoksnės tabletės formuluotės
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
US20130115622A1
(en)
|
2009-12-14 |
2013-05-09 |
Kyoto University |
Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis
|
|
EP2531163A1
(en)
|
2010-02-01 |
2012-12-12 |
The Hospital For Sick Children |
Remote ischemic conditioning for treatment and preventon of restenosis
|
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
|
JP2013523240A
(ja)
|
2010-03-31 |
2013-06-17 |
ザ・ホスピタル・フォー・シック・チルドレン |
心筋梗塞後の結果を改善するための遠隔虚血コンディショニングの使用
|
|
EP2555692A2
(en)
|
2010-04-08 |
2013-02-13 |
The Hospital For Sick Children |
Use of remote ischemic conditioning for traumatic injury
|
|
WO2011130459A1
(en)
|
2010-04-14 |
2011-10-20 |
Bristol-Myers Squibb Company |
Novel glucokinase activators and methods of using same
|
|
US8372877B2
(en)
|
2010-04-16 |
2013-02-12 |
Cumberland Pharmaceuticals |
Stabilized statin formulations
|
|
WO2011145022A1
(en)
|
2010-05-21 |
2011-11-24 |
Pfizer Inc. |
2-phenyl benzoylamides
|
|
EP2584903B1
(en)
|
2010-06-24 |
2018-10-24 |
Merck Sharp & Dohme Corp. |
Novel heterocyclic compounds as erk inhibitors
|
|
RU2016125229A
(ru)
|
2010-07-09 |
2018-12-04 |
БиЭйчВи ФАРМА, ИНК. |
Комбинированная система доставки с немедленным/замедленным высвобождением для лекарственных средств с коротким периодом полувыведения, в том числе для ремоглифлозина
|
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
|
AU2011285909B2
(en)
|
2010-08-02 |
2016-11-10 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of catenin (cadherin-associated protein), beta 1 (CTNNB1) gene expression using short interfering nucleic acid (siNA)
|
|
US9029341B2
(en)
|
2010-08-17 |
2015-05-12 |
Sirna Therapeutics, Inc. |
RNA interference mediated inhibition of hepatitis B virus (HBV) gene expression using short interfering nucleic acid (siNA)
|
|
US8883801B2
(en)
|
2010-08-23 |
2014-11-11 |
Merck Sharp & Dohme Corp. |
Substituted pyrazolo[1,5-a]pyrimidines as mTOR inhibitors
|
|
EP2613782B1
(en)
|
2010-09-01 |
2016-11-02 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as erk inhibitors
|
|
US9242981B2
(en)
|
2010-09-16 |
2016-01-26 |
Merck Sharp & Dohme Corp. |
Fused pyrazole derivatives as novel ERK inhibitors
|
|
KR20130137623A
(ko)
|
2010-10-06 |
2013-12-17 |
고쿠리츠다이가쿠호우진 도쿄다이가쿠 |
림프 부종 예방 치료제
|
|
DK2632472T3
(en)
|
2010-10-29 |
2018-03-19 |
Sirna Therapeutics Inc |
RNA INTERFERENCE-MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERRING NUCLEIC ACIDS (SINA)
|
|
TWI462739B
(zh)
|
2010-11-02 |
2014-12-01 |
Univ Kaohsiung Medical |
Sildenafil-同族物四級銨哌嗪鹽類之製備及醫療用途
|
|
WO2012087772A1
(en)
|
2010-12-21 |
2012-06-28 |
Schering Corporation |
Indazole derivatives useful as erk inhibitors
|
|
WO2012085191A1
(en)
|
2010-12-23 |
2012-06-28 |
Dsm Sinochem Pharmaceuticals Netherlands B.V. |
Crystalline form of pravastatine and process for the preparation thereof
|
|
TWI631963B
(zh)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
包含鈉-葡萄糖共同輸送體1與2之抑制劑的組合物與應用方法
|
|
RU2598842C2
(ru)
|
2011-01-20 |
2016-09-27 |
Мерк Шарп Энд Домэ Корп. |
Антагонисты рецептора минералокортикоидов
|
|
EP3009136A1
(en)
|
2011-01-31 |
2016-04-20 |
Cadila Healthcare Limited |
Treatment for lipodystrophy
|
|
WO2012112363A1
(en)
|
2011-02-14 |
2012-08-23 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
WO2012120414A2
(en)
|
2011-03-04 |
2012-09-13 |
Pfizer Inc. |
Edn3-like peptides and uses thereof
|
|
TW201242953A
(en)
|
2011-03-25 |
2012-11-01 |
Bristol Myers Squibb Co |
Imidazole prodrug LXR modulators
|
|
WO2012139495A1
(en)
|
2011-04-13 |
2012-10-18 |
Merck Sharp & Dohme Corp. |
Mineralocorticoid receptor antagonists
|
|
AU2012245971A1
(en)
|
2011-04-21 |
2013-10-17 |
Piramal Enterprises Limited |
A crystalline form of a salt of a morpholino sulfonyl indole derivative and a process for its preparation
|
|
WO2013055606A1
(en)
|
2011-10-13 |
2013-04-18 |
Merck Sharp & Dohme Corp. |
Mineralocorticoid receptor antagonists
|
|
WO2013063214A1
(en)
|
2011-10-27 |
2013-05-02 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
|
KR101466617B1
(ko)
|
2011-11-17 |
2014-11-28 |
한미약품 주식회사 |
오메가-3 지방산 및 HMG-CoA 환원효소 억제제를 포함하는 안정성이 증가된 경구용 복합 제제
|
|
EP2797641B1
(en)
|
2011-12-29 |
2019-07-10 |
Trustees Of Tufts College |
Functionalization of biomaterials to control regeneration and inflammation responses
|
|
JP6224624B2
(ja)
|
2012-02-02 |
2017-11-01 |
ザ・ユニバーシティ・オブ・シドニー |
涙膜安定性における改善
|
|
WO2013165816A2
(en)
|
2012-05-02 |
2013-11-07 |
Merck Sharp & Dohme Corp. |
SHORT INTERFERING NUCLEIC ACID (siNA) COMPOSITIONS
|
|
ES2698950T3
(es)
|
2012-05-10 |
2019-02-06 |
Bayer Pharma AG |
Anticuerpos capaces de unirse al Factor XI de coagulación y/o a su forma activada, Factor XIa, y usos de los mismos
|
|
CN104640856B
(zh)
|
2012-05-11 |
2017-09-15 |
复位治疗公司 |
作为隐花色素调节剂的含有咔唑的磺酰胺类
|
|
AU2013296803B2
(en)
|
2012-08-01 |
2018-03-08 |
Eric Ostertag |
Free flowing, frozen compositions comprising a therapeutic agent
|
|
US8729092B2
(en)
|
2012-09-24 |
2014-05-20 |
Terence J. Scallen |
Rosuvastatin enantiomer compounds
|
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
|
EP2900241B1
(en)
|
2012-09-28 |
2018-08-08 |
Merck Sharp & Dohme Corp. |
Novel compounds that are erk inhibitors
|
|
ES2728246T3
(es)
|
2012-11-20 |
2019-10-23 |
Lexicon Pharmaceuticals Inc |
Inhibidores del cotransportador 1 de sodio-glucosa
|
|
ES2651347T3
(es)
|
2012-11-28 |
2018-01-25 |
Merck Sharp & Dohme Corp. |
Composiciones y métodos para el tratamiento del cáncer
|
|
CA2895504A1
(en)
|
2012-12-20 |
2014-06-26 |
Merck Sharp & Dohme Corp. |
Substituted imidazopyridines as hdm2 inhibitors
|
|
EP2951180B1
(en)
|
2013-01-30 |
2018-05-02 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as hdm2 inhibitors
|
|
WO2014144037A1
(en)
|
2013-03-15 |
2014-09-18 |
Bristol-Myers Squibb Company |
Lxr modulators
|
|
CN105517536B
(zh)
|
2013-03-21 |
2019-08-16 |
优普顺药物公司美国分部 |
可注射的持续释放组合物及其用于治疗关节炎症及相关疼痛的方法
|
|
BR112015026513A2
(pt)
|
2013-04-17 |
2017-07-25 |
Pfizer |
derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
|
|
AU2013387996B2
(en)
|
2013-04-22 |
2015-12-10 |
Cadila Healthcare Limited |
A novel composition for nonalcoholic fatty liver disease (NAFLD)
|
|
EP3004053B1
(en)
|
2013-05-30 |
2021-03-24 |
Cadila Healthcare Limited |
A process for preparation of pyrroles having hypolipidemic hypocholesteremic activities
|
|
TW201636015A
(zh)
|
2013-07-05 |
2016-10-16 |
卡地拉保健有限公司 |
協同性組成物
|
|
IN2013MU02470A
(enExample)
|
2013-07-25 |
2015-06-26 |
Cadila Healthcare Ltd |
|
|
US9593113B2
(en)
|
2013-08-22 |
2017-03-14 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
|
EP3041938A1
(en)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Circular polynucleotides
|
|
IN2013MU02905A
(enExample)
|
2013-09-06 |
2015-07-03 |
Cadila Healthcare Ltd |
|
|
WO2015054089A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
WO2015051479A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
JP6536871B2
(ja)
|
2013-12-02 |
2019-07-03 |
国立大学法人京都大学 |
Fgfr3病の予防および治療剤ならびにそのスクリーニング方法
|
|
EP3613418A1
(en)
|
2014-01-17 |
2020-02-26 |
Ligand Pharmaceuticals, Inc. |
Methods and compositions for modulating hormone levels
|
|
WO2015120580A1
(en)
|
2014-02-11 |
2015-08-20 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
TWI690521B
(zh)
|
2014-04-07 |
2020-04-11 |
美商同步製藥公司 |
作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
|
|
US10328082B2
(en)
|
2014-05-30 |
2019-06-25 |
Pfizer Inc. |
Methods of use and combinations
|
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
|
EP3194024B1
(en)
|
2014-09-15 |
2020-08-05 |
The Board of Trustees of the Leland Stanford Junior University |
Targeting aneurysm disease by modulating phagocytosis pathways
|
|
WO2016055901A1
(en)
|
2014-10-08 |
2016-04-14 |
Pfizer Inc. |
Substituted amide compounds
|
|
EP4218812A1
(en)
|
2015-02-27 |
2023-08-02 |
The Board of Trustees of the Leland Stanford Junior University |
Combination therapy for treatment of atherosclerosis
|
|
BR112017023158A2
(pt)
|
2015-04-30 |
2018-07-24 |
Harvard College |
anticorpos anti-ap2 e agentes de ligação de antígeno para tratar distúrbios metabólicos
|
|
US10385017B2
(en)
|
2015-10-14 |
2019-08-20 |
Cadila Healthcare Limited |
Pyrrole compound, compositions and process for preparation thereof
|
|
EP3206672B1
(en)
|
2015-10-27 |
2018-03-14 |
Eupraxia Pharmaceuticals Inc. |
Sustained release formulations of local anesthetics
|
|
WO2018071283A1
(en)
|
2016-10-12 |
2018-04-19 |
Merck Sharp & Dohme Corp. |
Kdm5 inhibitors
|
|
US20180243263A1
(en)
|
2016-12-09 |
2018-08-30 |
Cadila Healthcare Ltd. |
Treatment for primary biliary cholangitis
|
|
CN110869051A
(zh)
|
2017-05-30 |
2020-03-06 |
小利兰·斯坦福大学托管委员会 |
对神经炎症性疾病的治疗
|
|
WO2019094312A1
(en)
|
2017-11-08 |
2019-05-16 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
WO2019094311A1
(en)
|
2017-11-08 |
2019-05-16 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
JP7356968B2
(ja)
|
2018-05-08 |
2023-10-05 |
国立大学法人 岡山大学 |
心血管疾患に有用な医薬
|
|
EP3824912A4
(en)
|
2018-07-19 |
2022-04-20 |
Kyoto University |
PLATEFORM CARTILAGE DERIVED FROM PLURIPOTENTS STEM CELLS AND METHODS FOR PRODUCTION OF PLATEFORM CARTILAGE
|
|
BR112021000139A2
(pt)
|
2018-07-19 |
2021-04-06 |
Astrazeneca Ab |
Métodos de tratamento da hfpef empregando dapagliflozina e composições compreendendo a mesma
|
|
EP3833667B1
(en)
|
2018-08-07 |
2024-03-13 |
Merck Sharp & Dohme LLC |
Prmt5 inhibitors
|
|
US12173026B2
(en)
|
2018-08-07 |
2024-12-24 |
Merck Sharp & Dohme Llc |
PRMT5 inhibitors
|
|
WO2020033282A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
BR112021004839A2
(pt)
|
2018-09-26 |
2021-06-08 |
Lexicon Pharmaceuticals, Inc. |
formas cristalinas de n-(1-((2-(dimetilamino)etil)amino)-2-metil-1-oxopropan-2-il)-4-(4-(2-metil-5-((2s,3r,4r,5s,6r)-3,4,5-triidróxi-6-(metiltio)tetraidro-2h-piran-2-il)benzil)fenil)butanamida e métodos de sua síntese
|
|
WO2020130147A1
(ja)
|
2018-12-21 |
2020-06-25 |
国立大学法人京都大学 |
ルブリシン局在軟骨様組織、その製造方法及びそれを含む関節軟骨損傷治療用組成物
|
|
CA3125765A1
(en)
|
2019-01-18 |
2020-07-23 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
TW202100155A
(zh)
|
2019-03-13 |
2021-01-01 |
國立大學法人濱松醫科大學 |
主動脈瘤的治療用醫藥組成物
|
|
MX2021012690A
(es)
|
2019-04-19 |
2022-01-31 |
Ligand Pharm Inc |
Formas cristalinas y metodos para producir formas cristalinas de un compuesto.
|
|
MA56036A
(fr)
|
2019-05-27 |
2022-04-06 |
Immatics Us Inc |
Vecteurs viraux et leur utilisation dans une thérapie cellulaire adoptive
|
|
US12441730B2
(en)
|
2019-12-17 |
2025-10-14 |
Merck Sharp & Dohme Llc |
PRMT5 inhibitors
|
|
JP7589247B2
(ja)
|
2019-12-17 |
2024-11-25 |
メルク・シャープ・アンド・ドーム・エルエルシー |
Prmt5阻害剤
|
|
WO2021126728A1
(en)
|
2019-12-17 |
2021-06-24 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
EP4108260A4
(en)
|
2020-02-21 |
2024-03-06 |
JSR Corporation |
Composition for alleviating pulmonary hypertension, method for predicting prognosis of pulmonary hypertension, method for assisting in determining severity of pulmonary hypertension, and method for assisting in diagnosing pulmonary hypertension
|
|
DE102020111571A1
(de)
|
2020-03-11 |
2021-09-16 |
Immatics US, Inc. |
Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
|
|
TW202220672A
(zh)
|
2020-07-27 |
2022-06-01 |
瑞典商阿斯特捷利康公司 |
用達格列淨治療慢性腎臟病之方法
|
|
AU2021316011A1
(en)
|
2020-07-29 |
2023-02-09 |
Amryt Pharmaceuticals Inc. |
Lomitapide for use in methods of treating hyperlipidemia and hypercholesterolemia in pediatric patients
|
|
US20220056411A1
(en)
|
2020-08-21 |
2022-02-24 |
Immatics US, Inc. |
Methods for isolating cd8+ selected t cells
|
|
WO2023275715A1
(en)
|
2021-06-30 |
2023-01-05 |
Pfizer Inc. |
Metabolites of selective androgen receptor modulators
|
|
WO2023144722A1
(en)
|
2022-01-26 |
2023-08-03 |
Astrazeneca Ab |
Dapagliflozin for use in the treatment of prediabetes or reducing the risk of developing type 2 diabetes
|
|
IL322769A
(en)
|
2023-03-02 |
2025-10-01 |
Carcimun Biotech Gmbh |
Means and methods for diagnosing cancer and/or acute inflammatory disease
|
|
WO2025147589A1
(en)
|
2024-01-05 |
2025-07-10 |
Osanni Bio, Inc. |
Implants, compositions, and methods for treating retinal diseases and disorders
|
|
WO2025168652A1
(en)
|
2024-02-05 |
2025-08-14 |
Astrazeneca Ab |
Azd-0780 in combination with a statin for use in lowering ldl-c levels and treating cardiovacular diseases
|
|
WO2025196153A1
(en)
|
2024-03-20 |
2025-09-25 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
WO2025196154A1
(en)
|
2024-03-20 |
2025-09-25 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
WO2025196155A1
(en)
|
2024-03-20 |
2025-09-25 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
WO2025238159A1
(en)
|
2024-05-16 |
2025-11-20 |
Astrazeneca Ab |
Combination therapy comprising azd0780 and ezetimibe
|