|
US4444784A
(en)
*
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
JPS56150037A
(en)
|
1980-04-22 |
1981-11-20 |
Sankyo Co Ltd |
Hydronaphthalene compound
|
|
US4432996A
(en)
*
|
1980-11-17 |
1984-02-21 |
Merck & Co., Inc. |
Hypocholesterolemic fermentation products and process of preparation
|
|
JPS57185275A
(en)
*
|
1981-05-07 |
1982-11-15 |
Sankyo Co Ltd |
Tetrahydro-dum-4 and tetrahydro-isodum-4 and their derivatives
|
|
JPS57185276A
(en)
*
|
1981-05-11 |
1982-11-15 |
Sankyo Co Ltd |
Dihydro-dum-4 and dihydro-isodum-4 and their derivative
|
|
JPS5815968A
(ja)
*
|
1981-07-21 |
1983-01-29 |
Sankyo Co Ltd |
Ml−236b誘導体およびその製法
|
|
JPS5835144A
(ja)
*
|
1981-08-27 |
1983-03-01 |
Sankyo Co Ltd |
Mb−530b誘導体およびその製造法
|
|
JPS5889191A
(ja)
*
|
1981-11-20 |
1983-05-27 |
Sankyo Co Ltd |
3−ヒドロキシ−ml−236b誘導体の製造法
|
|
PH20405A
(en)
*
|
1983-07-21 |
1987-01-05 |
Fujisawa Pharmaceutical Co |
Anti-tumor agent container fr.900216 substance or its pharmaceutically acceptable salts thereof
|
|
EP0164049B1
(de)
*
|
1984-06-04 |
1990-12-12 |
Merck & Co. Inc. |
Herstellungsverfahren von Hemmstoffen der HMG-CoA-Reduktase mit einer 3,5-Dihydroxypentanoatteilstruktur
|
|
US4611068A
(en)
*
|
1984-11-19 |
1986-09-09 |
Merck Frosst Canada, Inc. |
Process for the preparation of HMG-CoA reductase inhibitors and intermediate compounds employed therein
|
|
EP0204287A3
(de)
*
|
1985-06-04 |
1987-07-01 |
Merck & Co. Inc. |
Herstellungsverfahren von HMG-CoA-Reduktase-Hemmstoffen mit 3,5-Dihydroxypentansäureeinheiten
|
|
US4611081A
(en)
*
|
1985-07-05 |
1986-09-09 |
Merck & Co., Inc. |
Process for the preparation of HMG-CoA reductase inhibitors intermediates
|
|
USRE33033E
(en)
*
|
1985-07-05 |
1989-08-22 |
Merck & Co., Inc. |
Process for the preparation of HMG-CoA reductase inhibitors intermediates
|
|
US4668699A
(en)
*
|
1985-08-05 |
1987-05-26 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
DE3682557D1
(de)
*
|
1985-09-13 |
1992-01-02 |
Sankyo Co |
Hydroxy-ml-236b-derivate, deren herstellung und anwendung.
|
|
US5272174A
(en)
*
|
1985-09-13 |
1993-12-21 |
Sankyo Company, Limited |
Hydroxy-ML-236B derivatives, their preparation and use
|
|
JPH0633312B2
(ja)
*
|
1986-05-02 |
1994-05-02 |
大正製薬株式会社 |
14−ハイドロキシエリスロマイシン誘導体およびその製造方法
|
|
EP0245003A3
(de)
*
|
1986-05-05 |
1989-07-19 |
Merck & Co. Inc. |
Antihypercholesterolemische Verbindungen
|
|
US4661483A
(en)
*
|
1986-05-05 |
1987-04-28 |
Merck & Co., Inc. |
Antihypercholesterolemic lactone compounds, compositions and use
|
|
US4771071A
(en)
*
|
1986-05-05 |
1988-09-13 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4766145A
(en)
*
|
1986-05-05 |
1988-08-23 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4847306A
(en)
*
|
1986-05-05 |
1989-07-11 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
EP0245990A3
(de)
*
|
1986-05-05 |
1989-07-19 |
Merck & Co. Inc. |
Antihypercholesterolemische Verbindungen
|
|
US4864038A
(en)
*
|
1986-05-05 |
1989-09-05 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US4937264A
(en)
*
|
1986-05-05 |
1990-06-26 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
EP0245004A3
(de)
*
|
1986-05-05 |
1989-07-26 |
Merck & Co. Inc. |
Antihypercholesterolemische Verbindungen
|
|
US5116870A
(en)
*
|
1986-06-23 |
1992-05-26 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
|
USRE36481E
(en)
*
|
1986-06-23 |
2000-01-04 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors
|
|
US4940727A
(en)
*
|
1986-06-23 |
1990-07-10 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
AU1422388A
(en)
*
|
1987-01-27 |
1988-08-10 |
Warner-Lambert Company |
Lipid regulating compositions
|
|
US4833258A
(en)
*
|
1987-02-17 |
1989-05-23 |
Merck & Co., Inc. |
Intermediates useful in the preparation of HMG-COA reductase inhibitors
|
|
EP0306263B1
(de)
*
|
1987-09-02 |
1992-03-18 |
Merck & Co. Inc. |
Inhibitoren von HMG-CoA-Reduktase
|
|
US4997848A
(en)
|
1987-10-27 |
1991-03-05 |
Sankyo Company, Limited |
Octahydronaphthalene oxime derivatives for cholesterol synthesis inhibition
|
|
US4857547A
(en)
*
|
1988-01-07 |
1989-08-15 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
|
US5021453A
(en)
*
|
1988-03-02 |
1991-06-04 |
Merck & Co., Inc. |
3-keto HMG-CoA reductase inhibitors
|
|
US4857522A
(en)
*
|
1988-03-21 |
1989-08-15 |
E. R. Squibb & Sons, Inc. |
Derivatives of pravastatin for inhibiting cholesterol biosynthesis
|
|
US5155229A
(en)
*
|
1988-03-21 |
1992-10-13 |
E. R. Squibb & Sons, Inc. |
Derivatives of pravastatin and method of making the same
|
|
US5047549A
(en)
*
|
1988-03-21 |
1991-09-10 |
E. R. Squibb & Sons, Inc. |
Derivatives of pravastatin for inhibiting cholesterol biosynthesis
|
|
US5030447A
(en)
*
|
1988-03-31 |
1991-07-09 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions having good stability
|
|
US5180589A
(en)
*
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
|
US4997755A
(en)
*
|
1988-04-15 |
1991-03-05 |
Merck & Co., Inc. |
HMG-CoA reductase inhibitors produced by Nocardia sp. (MA 6455)
|
|
US4963538A
(en)
*
|
1988-06-29 |
1990-10-16 |
Merck & Co., Inc. |
5-oxygenated HMG-CoA reductase inhibitors
|
|
US5075327A
(en)
*
|
1988-08-10 |
1991-12-24 |
Hoffmann-La Roche Inc. |
Antipsoriatic agents
|
|
US5073568A
(en)
*
|
1988-11-14 |
1991-12-17 |
Hoffmann-La Roche Inc. |
Antipsoriatic agents
|
|
US5200549A
(en)
*
|
1988-11-14 |
1993-04-06 |
Hoffman-La Roche Inc. |
Antipsoriatic agents
|
|
US5021451A
(en)
*
|
1988-11-14 |
1991-06-04 |
Hoffman-La Roche Inc. |
Method for inhibiting hyperproliferative diseases
|
|
US5376383A
(en)
*
|
1988-11-21 |
1994-12-27 |
Merck & Co., Inc. |
Method for enhancing the lowering of plasma-cholesterol levels
|
|
US5260305A
(en)
*
|
1988-12-12 |
1993-11-09 |
E. R. Squibb & Sons, Inc. |
Combination of pravastatin and nicotinic acid or related acid and method for lowering serum cholesterol using such combination
|
|
JP2763782B2
(ja)
*
|
1989-02-14 |
1998-06-11 |
旭電化工業株式会社 |
メバロン酸の製造方法
|
|
US5166364A
(en)
*
|
1989-02-27 |
1992-11-24 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives useful as antihypercholesterolemic agents and method for preparing same
|
|
CA2016467A1
(en)
|
1989-06-05 |
1990-12-05 |
Martin Eisman |
Method for treating peripheral atherosclerotic disease employing an hmg coa reductase inhibitor and/or a squalene synthetase inhibitor
|
|
US5001148A
(en)
*
|
1989-06-07 |
1991-03-19 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
|
US4937259A
(en)
*
|
1989-06-09 |
1990-06-26 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US5010105A
(en)
*
|
1989-06-09 |
1991-04-23 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
|
US5102911A
(en)
*
|
1989-06-09 |
1992-04-07 |
Merck & Co, Inc. |
4-Substituted HMG-CoA reductase inhibitors
|
|
US5001241A
(en)
*
|
1989-06-09 |
1991-03-19 |
Merck & Co., Inc. |
3-KETO HMG-CoA reductase inhibitors
|
|
US4970231A
(en)
*
|
1989-06-09 |
1990-11-13 |
Merck & Co., Inc. |
4-substituted HMG-CoA reductase inhibitors
|
|
US5041562A
(en)
*
|
1989-06-09 |
1991-08-20 |
Merck & Co., Inc. |
3-keto HMG-CoA reductase inhibitors
|
|
US4965200A
(en)
*
|
1989-06-23 |
1990-10-23 |
Merck & Co., Inc. |
Process for the preparation of 3-keto, 5-hydroxy simvastatin analogs
|
|
US4997849A
(en)
*
|
1989-06-23 |
1991-03-05 |
Merck & Co., Inc. |
Microbial transformation of simvastatin
|
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
|
US5316765A
(en)
*
|
1989-09-07 |
1994-05-31 |
Karl Folkers Foundation For Biomedical And Clinical Research |
Use of coenzyme Q10 in combination with HMG-CoA reductase inhibitor therapies
|
|
US5212296A
(en)
*
|
1989-09-11 |
1993-05-18 |
E. I. Du Pont De Nemours And Company |
Expression of herbicide metabolizing cytochromes
|
|
US5173487A
(en)
*
|
1989-11-13 |
1992-12-22 |
E. R. Squibb & Sons, Inc. |
Mevinic acid derivatives
|
|
US5177104A
(en)
*
|
1990-04-03 |
1993-01-05 |
E. R. Squibb & Sons, Inc. |
6-α-hydroxy derivatives of mevinic acids
|
|
GB9007738D0
(en)
*
|
1990-04-05 |
1990-06-06 |
British Bio Technology |
Compounds
|
|
US5089523A
(en)
*
|
1990-05-11 |
1992-02-18 |
E. R. Squibb & Sons, Inc. |
Fluorinated derivatives of mevinic acids
|
|
US6630502B2
(en)
|
1990-05-15 |
2003-10-07 |
E.R. Squibb & Sons, Inc. |
Method for preventing, stabilizing or causing regression of atherosclerosis employing a combination of a cholesterol lowering drug and an ace inhibitor
|
|
US5140012A
(en)
*
|
1990-05-31 |
1992-08-18 |
E. R. Squibb & Sons, Inc. |
Method for preventing onset of restenosis after angioplasty employing pravastatin
|
|
US5622985A
(en)
*
|
1990-06-11 |
1997-04-22 |
Bristol-Myers Squibb Company |
Method for preventing a second heart attack employing an HMG CoA reductase inhibitor
|
|
US5264455A
(en)
*
|
1990-07-06 |
1993-11-23 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
|
US5223415A
(en)
*
|
1990-10-15 |
1993-06-29 |
Merck & Co., Inc. |
Biosynthetic production of 7-[1',2',6',7',8',8a'(R)-hexahydro-2'(S),6'(R)-dimethyl-8'(S)-hydroxy-1'(S)-naphthyl]-3(R),5(R)-dihydroxyheptanoic acid (triol acid)
|
|
US5225202A
(en)
*
|
1991-09-30 |
1993-07-06 |
E. R. Squibb & Sons, Inc. |
Enteric coated pharmaceutical compositions
|
|
US5286746A
(en)
*
|
1991-12-20 |
1994-02-15 |
E. R. Squibb & Sons, Inc. |
Sulfur-substituted mevinic acid derivatives
|
|
US5620876A
(en)
*
|
1992-04-29 |
1997-04-15 |
E. R. Squibb & Sons, Inc. |
Enzymatic hydrolysis and esterification processes for the preparation of HMG-CoA reductase inhibitors and intermediates thereof
|
|
ZA933359B
(en)
|
1992-05-15 |
1993-12-08 |
Sankyo Co |
Octahydronaphthalene oxime derivatives for cholesterol biosynthesis inhibition, their preparation and use
|
|
US5369123A
(en)
*
|
1992-10-09 |
1994-11-29 |
E. R. Squibb & Sons, Inc. |
Nitrogen-substituted mevinic acid derivatives useful as HMG-CoA reductase inhibitors
|
|
NZ250609A
(en)
*
|
1992-12-28 |
1995-07-26 |
Sankyo Co |
Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments
|
|
IL108432A
(en)
*
|
1993-01-29 |
1997-09-30 |
Sankyo Co |
DERIVATIVES OF 3, 5-DIHYDROXY-7- £1, 2, 6, 7, 8, 8a-HEXAHYDRO-2- METHYL-8- (SUBSTITUTED ALKANOYLOXY)-1-NAPHTHYL| HEPTANOIC ACID AND THEIR LACTONES, THEIR PREPARATION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
|
|
FR2709126B1
(fr)
*
|
1993-08-18 |
1995-09-29 |
Adir |
Nouveaux dérivés de naphtalène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
|
|
US6043064A
(en)
*
|
1993-10-22 |
2000-03-28 |
Bristol-Myers Squibb Company |
Enzymatic hydroxylation process for the preparation of HMG-CoA reductase inhibitors and intermediates thereof
|
|
WO1995012661A1
(en)
*
|
1993-11-02 |
1995-05-11 |
Merck & Co., Inc. |
Dna encoding triol polyketide synthase
|
|
WO1995013063A1
(en)
*
|
1993-11-09 |
1995-05-18 |
Merck & Co., Inc. |
HMG-CoA REDUCTASE INHIBITORS IN THE NORMALIZATION OF VASCULAR ENDOTHELIAL DYSFUNCTION
|
|
US6369103B1
(en)
|
1994-01-18 |
2002-04-09 |
Bristol-Myers Squibb Company |
Method for preventing or reducing risk of onset of cardiovascular events employing an HMG CoA reductase inhibitor
|
|
US5681278A
(en)
*
|
1994-06-23 |
1997-10-28 |
Cormedics Corp. |
Coronary vasculature treatment method
|
|
US6642268B2
(en)
|
1994-09-13 |
2003-11-04 |
G.D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors
|
|
US6268392B1
(en)
|
1994-09-13 |
2001-07-31 |
G. D. Searle & Co. |
Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors
|
|
US6262277B1
(en)
*
|
1994-09-13 |
2001-07-17 |
G.D. Searle And Company |
Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake
|
|
US5616595A
(en)
*
|
1995-06-07 |
1997-04-01 |
Abbott Laboratories |
Process for recovering water insoluble compounds from a fermentation broth
|
|
US5942423A
(en)
|
1995-06-07 |
1999-08-24 |
Massachusetts Institute Of Technology |
Conversion of compactin to pravastatin by actinomadura
|
|
US5900433A
(en)
*
|
1995-06-23 |
1999-05-04 |
Cormedics Corp. |
Vascular treatment method and apparatus
|
|
HUP9601808A3
(en)
*
|
1995-07-03 |
2000-06-28 |
Sankyo Co |
Treatment of arteriosclerosis and xanthoma
|
|
KR100186758B1
(ko)
*
|
1996-08-09 |
1999-04-01 |
영진약품공업 주식회사 |
프라바스타틴(pravastatin)전구체의제조방법
|
|
AU727895B2
(en)
*
|
1997-01-17 |
2001-01-04 |
Bristol-Myers Squibb Company |
Method for treating atherosclerosis with an MPT inhibitor and cholesterol lowering drugs
|
|
US6066653A
(en)
*
|
1997-01-17 |
2000-05-23 |
Bristol-Myers Squibb Co. |
Method of treating acid lipase deficiency diseases with an MTP inhibitor and cholesterol lowering drugs
|
|
KR100210482B1
(ko)
*
|
1997-04-10 |
1999-07-15 |
김종인 |
스트렙토마이세스엑스포리아투스(streptomycesexfoliatus)yj-118과이를이용한프라바스타틴나트륨의제조방법
|
|
EP0877089A1
(de)
|
1997-05-07 |
1998-11-11 |
Gist-Brocades B.V. |
Verfahren zur Herstellung eines Inhibitors der Hmg-Coa Reduktase
|
|
US20010006644A1
(en)
|
1997-07-31 |
2001-07-05 |
David J. Bova |
Combinations of hmg-coa reductase inhibitors and nicotinic acid and methods for treating hyperlipidemia once a day at night
|
|
US6245535B1
(en)
|
1997-08-07 |
2001-06-12 |
Kyowa Hakko Kogyo Co., Ltd. |
Process for the preparation of HMG-COA reductase inhibitors
|
|
EP1015600A1
(de)
*
|
1997-08-22 |
2000-07-05 |
Dsm N.V. |
Fermentative herstellung von statin
|
|
GT199800127A
(es)
*
|
1997-08-29 |
2000-02-01 |
|
Combinaciones terapeuticas.
|
|
US6177121B1
(en)
|
1997-09-29 |
2001-01-23 |
Purdue Research Foundation |
Composition and method for producing low cholesterol eggs
|
|
US6147109A
(en)
*
|
1997-10-14 |
2000-11-14 |
The General Hospital Corporation |
Upregulation of Type III endothelial cell Nitric Oxide Synthase by HMG-CoA reductase inhibitors
|
|
US6083497A
(en)
|
1997-11-05 |
2000-07-04 |
Geltex Pharmaceuticals, Inc. |
Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers
|
|
US20080275104A1
(en)
*
|
1997-11-25 |
2008-11-06 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
|
US20040029962A1
(en)
*
|
1997-12-12 |
2004-02-12 |
Chih-Ming Chen |
HMG-COA reductase inhibitor extended release formulation
|
|
US20060141036A1
(en)
*
|
1997-12-12 |
2006-06-29 |
Andrx Labs Llc |
HMG-CoA reductase inhibitor extended release formulation
|
|
US6180597B1
(en)
|
1998-03-19 |
2001-01-30 |
Brigham And Women's Hospital, Inc. |
Upregulation of Type III endothelial cell nitric oxide synthase by rho GTPase function inhibitors
|
|
SI9800144A
(sl)
|
1998-05-21 |
1999-12-31 |
LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. |
Nov biotehnološki postopek pridobivanja 3-hidroksi-ML-236B derivatov poznanih kot M-4 in M-4'
|
|
US20030078211A1
(en)
*
|
1998-06-24 |
2003-04-24 |
Merck & Co., Inc. |
Compositions and methods for inhibiting bone resorption
|
|
CA2336201A1
(en)
|
1998-06-24 |
1999-12-29 |
Merck & Co., Inc. |
Compositions and methods for inhibiting bone resorption
|
|
US6423751B1
(en)
|
1998-07-14 |
2002-07-23 |
The Brigham And Women's Hospital, Inc. |
Upregulation of type III endothelial cell nitric oxide synthase by agents that disrupt actin cytoskeletal organization
|
|
US5985907A
(en)
*
|
1998-08-12 |
1999-11-16 |
Health Research, Inc. |
Method for inhibiting growth of methanogens
|
|
SI20070A
(sl)
*
|
1998-09-18 |
2000-04-30 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Nove soli inhibitorjev HMG-CoA reduktaze
|
|
SI20305A
(sl)
*
|
1999-08-06 |
2001-02-28 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Kristali natrijeve soli pravastatina
|
|
US8293277B2
(en)
*
|
1998-10-01 |
2012-10-23 |
Alkermes Pharma Ireland Limited |
Controlled-release nanoparticulate compositions
|
|
US20080213378A1
(en)
*
|
1998-10-01 |
2008-09-04 |
Elan Pharma International, Ltd. |
Nanoparticulate statin formulations and novel statin combinations
|
|
WO2000030616A1
(en)
|
1998-11-20 |
2000-06-02 |
Rtp Pharma Inc. |
Dispersible phospholipid stabilized microparticles
|
|
SI20109A
(sl)
*
|
1998-12-16 |
2000-06-30 |
LEK, tovarna farmacevtskih in kemi�nih izdelkov, d.d. |
Stabilna farmacevtska formulacija
|
|
US6391583B1
(en)
|
1998-12-18 |
2002-05-21 |
Wisconsin Alumni Research Foundation |
Method of producing antihypercholesterolemic agents
|
|
AU779264B2
(en)
*
|
1998-12-23 |
2005-01-13 |
G.D. Searle Llc |
Combinations for cardiovascular indications
|
|
WO2000038722A1
(en)
|
1998-12-23 |
2000-07-06 |
G.D. Searle & Co. |
COMBINATIONS OF CHOLESTERYL ESTER TRANSFER PROTEIN INHIBITORS AND HMG CoA REDUCTASE INHIBITORS FOR CARDIOVASCULAR INDICATIONS
|
|
ES2189529T3
(es)
|
1998-12-23 |
2003-07-01 |
Searle Llc |
Combinaciones de inhiidores para el transporte de acidos biliares en el ileon y agentes complejantes para indicaciones cardiovasculares.
|
|
ATE242009T1
(de)
|
1998-12-23 |
2003-06-15 |
Searle Llc |
Kombinationen von cholesteryl ester transfer protein inhibitoren und fibronsäure derivaten für kardiovaskuläre indikationen
|
|
ES2201822T3
(es)
*
|
1998-12-23 |
2004-03-16 |
G.D. Searle Llc |
Combinaciones de inhibididores de la proteina de transferencia de ester de colesterilo y de derivados de acido nicotinico para indicaciones cardiovasculares.
|
|
BR9916565A
(pt)
*
|
1998-12-23 |
2002-01-29 |
Searle Llc |
Combinações de inibidores do transporte ácido da bile ileal e derivados do ácido fìbrico para indicações cardiovasculares
|
|
PT1140185E
(pt)
|
1998-12-23 |
2003-10-31 |
Searle Llc |
Combinacoes de inibidores de proteina de transferencia de ester de colesterilo com agentes sequestrantes de acido biliar para indicacoes cardiovasculares
|
|
CA2356422C
(en)
|
1998-12-23 |
2008-09-16 |
G.D. Searle Llc |
Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications
|
|
CA2358927A1
(en)
|
1999-01-20 |
2000-07-27 |
Shin-Ichi Hashimoto |
Process for producing hmg-coa reductase inhibitors
|
|
CA2360080A1
(en)
|
1999-01-29 |
2000-08-03 |
Kyowa Hakko Kogyo Co. Ltd. |
Process for producing hmg-coa reductase inhibitor
|
|
US6682913B1
(en)
|
1999-02-03 |
2004-01-27 |
Institute For Drug Research Ltd. |
Microbial process for preparing pravastatin
|
|
US6569461B1
(en)
|
1999-03-08 |
2003-05-27 |
Merck & Co., Inc. |
Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors
|
|
HUP9902352A1
(hu)
*
|
1999-07-12 |
2000-09-28 |
Gyógyszerkutató Intézet Kft. |
Eljárás pravasztatin mikrobiológiai előállítására
|
|
SE9903028D0
(sv)
*
|
1999-08-27 |
1999-08-27 |
Astra Ab |
New use
|
|
BR0013704A
(pt)
*
|
1999-08-30 |
2002-05-07 |
Aventis Pharma Gmbh |
Uso de inibidores do sistema renina-angiotensina na prevenção de casos cardiovasculares
|
|
MXPA02005283A
(es)
|
1999-11-30 |
2003-10-06 |
Biogal Gyogyszergyar |
Proceso para recuperar compuestos estatina de un caldo de fermentacion.
|
|
CZ20021998A3
(cs)
*
|
1999-12-14 |
2003-02-12 |
Biogal Gyogyszergyar Rt. |
Nové formy sodné soli pravastatinu
|
|
IN191580B
(de)
*
|
1999-12-17 |
2003-12-06 |
Ranbaxy Lab Ltd |
|
|
CA2398199A1
(en)
*
|
2000-01-28 |
2001-08-02 |
Asahi Kasei Kabushiki Kaisha |
Novel therapeutic agents that use a .beta.3 agonist
|
|
EP1267914B2
(de)
*
|
2000-02-04 |
2013-11-06 |
Children's Hospital Research Foundation |
Verwendung von lysosomal acid lipase zur behandlung von atherosklerose und ähnlichen krankheiten
|
|
US6794544B2
(en)
|
2000-03-10 |
2004-09-21 |
Pharmacia Corporation |
Method for the preparation of tetrahydrobenzothiepines
|
|
US6395767B2
(en)
|
2000-03-10 |
2002-05-28 |
Bristol-Myers Squibb Company |
Cyclopropyl-fused pyrrolidine-based inhibitors of dipeptidyl peptidase IV and method
|
|
AU2001247331A1
(en)
*
|
2000-03-10 |
2001-09-24 |
Pharmacia Corporation |
Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
|
|
DK1274401T4
(da)
|
2000-04-10 |
2014-09-08 |
Teva Pharma |
Stabile farmaceutiske sammensætninger indeholdende 7-substituerede-3,5-dihydroxyheptansyrer eller 7-substituerede-3,5-dihydroxyheptensyrer
|
|
CA2406383A1
(en)
*
|
2000-04-13 |
2001-10-25 |
Mayo Foundation For Medical Education And Research |
A.beta.42 lowering agents
|
|
DE10030375A1
(de)
*
|
2000-06-21 |
2002-01-03 |
Bayer Ag |
Verwendung von MTP-Inhibitoren zur Senkung von ppTRL
|
|
EP1314425A4
(de)
*
|
2000-08-30 |
2004-06-02 |
Sankyo Co |
Medizinische zusammenstellung zur prophylaxe und behandlung von herzversagen
|
|
JO2654B1
(en)
|
2000-09-04 |
2012-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Multiple aryl caroxa amides are useful as lipid - lowering agents
|
|
US8586094B2
(en)
|
2000-09-20 |
2013-11-19 |
Jagotec Ag |
Coated tablets
|
|
US6936731B2
(en)
*
|
2000-10-05 |
2005-08-30 |
TEVA Gyógyszergyár Részvénytársaság |
Pravastatin sodium substantially free of pravastatin lactone and epi-pravastatin, and compositions containing same
|
|
CN1468098A
(zh)
*
|
2000-10-05 |
2004-01-14 |
�ݰ¸Ƕ�ҩ������˾ |
基本上无普伐他汀内酯和表普伐他汀的普伐他汀钠和包含普伐他汀钠的组合物
|
|
US20050215636A1
(en)
*
|
2000-10-05 |
2005-09-29 |
Vilmos Keri |
Pravastatin sodium substantially free of pravastatin lactone and EPI-pravastatin, and compositions containing same
|
|
US6534540B2
(en)
|
2000-10-06 |
2003-03-18 |
George Kindness |
Combination and method of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor
|
|
US20030162829A1
(en)
*
|
2000-10-06 |
2003-08-28 |
George Kindness |
Combination of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor
|
|
JP2002121172A
(ja)
*
|
2000-10-16 |
2002-04-23 |
Sankyo Co Ltd |
プラバスタチン又はその薬理上許容される塩の精製方法
|
|
JP3236282B1
(ja)
*
|
2000-10-16 |
2001-12-10 |
三共株式会社 |
プラバスタチンを精製する方法
|
|
US6916849B2
(en)
|
2000-10-23 |
2005-07-12 |
Sankyo Company, Limited |
Compositions for improving lipid content in the blood
|
|
CA2428204A1
(en)
|
2000-11-07 |
2002-05-16 |
Sankyo Company, Limited |
Lipid peroxide-lowering compositions
|
|
US6777552B2
(en)
|
2001-08-16 |
2004-08-17 |
Teva Pharmaceutical Industries, Ltd. |
Processes for preparing calcium salt forms of statins
|
|
JO2409B1
(en)
*
|
2000-11-21 |
2007-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Second-phenyl carboxy amides are useful as lipid-lowering agents
|
|
US20030232834A1
(en)
*
|
2001-03-08 |
2003-12-18 |
Keller Bradley T |
Combination therapy for the prophylaxis and treatment of hyperlipidemic conditions and disorders
|
|
EE200300468A
(et)
*
|
2001-03-27 |
2004-02-16 |
Ranbaxy Laboratories Limited |
Pravastatiini stabiilne farmatseutiline kompositsioon
|
|
JO2390B1
(en)
*
|
2001-04-06 |
2007-06-17 |
شركة جانسين فارماسوتيكا ان. في |
Diphenylcarboxamides act as lipid-lowering agents
|
|
ATE318272T1
(de)
|
2001-04-11 |
2006-03-15 |
Bristol Myers Squibb Co |
Aminosäurekomplexe von c-arylglycosiden zur behandlung von diabetes und verfahren
|
|
WO2002085382A1
(en)
|
2001-04-18 |
2002-10-31 |
Genzyme Corporation |
Methods of treating syndrome x with aliphatic polyamines
|
|
EP1390030A1
(de)
*
|
2001-05-31 |
2004-02-25 |
Cellegy Pharmaceuticals, Inc |
Speicherbetätigte calcium-einström-hemmer und verfahren zu ihrer anwendung
|
|
WO2003000239A1
(en)
*
|
2001-06-21 |
2003-01-03 |
Andrx Pharmaceuticals, Inc. |
Stable pharmaceutical compositions containing pravastatin
|
|
US20040180087A1
(en)
*
|
2001-06-21 |
2004-09-16 |
Boyong Li |
Stable controlled release pharmaceutical compositions containing pravastatin
|
|
US20040092565A1
(en)
*
|
2001-07-25 |
2004-05-13 |
George Kindness |
Composition and method of sustaining chemotherapeutic effect while reducing dose of chemotherapeutic agent using cox-2 inhibitor and statin
|
|
US20040077625A1
(en)
*
|
2001-07-25 |
2004-04-22 |
Tremont Samuel J. |
Novel 1,4-benzothiazepine and 1,5-benzothiazepine compounds as inhibitors of apical sodium codependent bile acid transport abd taurocholate uptake
|
|
EP1430138B1
(de)
|
2001-09-27 |
2006-01-18 |
Biocon Limited |
Verfahren zur herstellung von pravastatin-natriumsalz mittels streptomyces flavidovirens dsm 14455
|
|
KR100414334B1
(ko)
*
|
2001-09-29 |
2004-01-07 |
코바이오텍 (주) |
프라바스타틴 나트륨의 생산 방법
|
|
MXPA04003553A
(es)
*
|
2001-10-18 |
2004-07-22 |
Bristol Myers Squibb Co |
Mimeticos del peptido-1 similares aglucagon humano y su uso en tratamiento de diabetes y condiciones relacionadas.
|
|
US7238671B2
(en)
*
|
2001-10-18 |
2007-07-03 |
Bristol-Myers Squibb Company |
Human glucagon-like-peptide-1 mimics and their use in the treatment of diabetes and related conditions
|
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
|
JP2005518347A
(ja)
*
|
2001-11-02 |
2005-06-23 |
ジー.ディー. サール エルエルシー |
頂端ナトリウム共依存性胆汁酸輸送(asbt)およびタウロコール酸塩取り込みの阻害剤としての新規一および二フッ化ベンゾチエピン化合物
|
|
US6984645B2
(en)
*
|
2001-11-16 |
2006-01-10 |
Bristol-Myers Squibb Company |
Dual inhibitors of adipocyte fatty acid binding protein and keratinocyte fatty acid binding protein
|
|
US6831102B2
(en)
*
|
2001-12-07 |
2004-12-14 |
Bristol-Myers Squibb Company |
Phenyl naphthol ligands for thyroid hormone receptor
|
|
EP1465869B1
(de)
|
2001-12-21 |
2013-05-15 |
Exelixis Patent Company LLC |
Modulatoren von lxr
|
|
US7482366B2
(en)
|
2001-12-21 |
2009-01-27 |
X-Ceptor Therapeutics, Inc. |
Modulators of LXR
|
|
WO2003060078A2
(en)
*
|
2001-12-21 |
2003-07-24 |
X-Ceptor Therapeutics, Inc. |
Heterocyclic modulators of nuclear receptors
|
|
BR0306643A
(pt)
|
2002-01-17 |
2004-10-19 |
Pharmacia Corp |
Novos compostos de hidroxi alquil/aril ou ceto tiepina como inibidores do transporte co-dependente de ácido biliar-sódio apical
|
|
KR100379075B1
(en)
*
|
2002-03-07 |
2003-04-08 |
Jinis Biopharmaceuticals Co |
Method for producing low cholesterol animal food product and food product therefrom
|
|
JP4308021B2
(ja)
*
|
2002-03-18 |
2009-08-05 |
バイオコン・リミテッド |
望ましい粒子サイズのアモルファスHMG−CoAレダクターゼ阻害剤
|
|
EP1490029A4
(de)
*
|
2002-03-22 |
2006-02-22 |
Ranbaxy Lab Ltd |
Arzneimittelabgabesystem zur kontrollierten freisetzung von pravastatin
|
|
US20050113577A1
(en)
*
|
2002-04-16 |
2005-05-26 |
Karki Shyam B. |
Solid forms of slats with tyrosine kinase activity
|
|
US6747048B2
(en)
|
2002-05-08 |
2004-06-08 |
Bristol-Myers Squibb Company |
Pyridine-based thyroid receptor ligands
|
|
DK1532269T3
(da)
|
2002-05-09 |
2012-03-12 |
Brigham & Womens Hospital |
1L1RL-1 som markør for kardiovaskulær sygdom
|
|
EP1504525A2
(de)
*
|
2002-05-14 |
2005-02-09 |
Siemens Aktiengesellschaft |
Verfahren zum erzeugen eines sendesignals
|
|
US7057046B2
(en)
*
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
|
US7763278B2
(en)
*
|
2002-06-10 |
2010-07-27 |
Elan Pharma International Ltd. |
Nanoparticulate polycosanol formulations and novel polycosanol combinations
|
|
US20050182106A1
(en)
*
|
2002-07-11 |
2005-08-18 |
Sankyo Company, Limited |
Medicinal composition for mitigating blood lipid or lowering blood homocysteine
|
|
MXPA05000913A
(es)
*
|
2002-07-23 |
2005-03-23 |
Nutrinova Gmbh |
Agente reductor de colesterol hecho a partir de fibra dietetica y sustancias reductoras de colesterol.
|
|
US20050182036A1
(en)
*
|
2002-08-02 |
2005-08-18 |
Sankyo Company, Limited |
Medicinal composition containing an HMG-CoA reductase inhibitor
|
|
US20050187204A1
(en)
*
|
2002-08-08 |
2005-08-25 |
Sankyo Company, Limited |
Medicinal composition for lowering blood lipid level
|
|
UA79300C2
(en)
*
|
2002-08-12 |
2007-06-11 |
Janssen Pharmaceutica Nv |
N-aryl piperidine substituted biphenylcarboxamides as inhibitors of apolipoprotein b secretion
|
|
US20040138187A1
(en)
|
2002-08-28 |
2004-07-15 |
Reading Christopher L. |
Therapeutic treatment methods
|
|
US20060019269A1
(en)
*
|
2002-10-17 |
2006-01-26 |
Decode Genetics, Inc. |
Susceptibility gene for myocardial infarction, stroke, and PAOD, methods of treatment
|
|
US20080293750A1
(en)
*
|
2002-10-17 |
2008-11-27 |
Anna Helgadottir |
Susceptibility Gene for Myocardial Infarction, Stroke, Paod and Methods of Treatment
|
|
ATE469645T1
(de)
*
|
2002-10-23 |
2010-06-15 |
Bristol Myers Squibb Co |
Auf glycinnitril basierende hemmer der dipeptidylpeptidase iv
|
|
US20080145424A1
(en)
*
|
2002-10-24 |
2008-06-19 |
Enos Phramaceuticals, Inc. |
Sustained release L-arginine formulations and methods of manufacture and use
|
|
EP1562555A2
(de)
*
|
2002-10-24 |
2005-08-17 |
Enos Pharmaceuticals, Inc. |
L-arginin-formulierungen mit verzögerterfreisetzung und herstellungs- und verwendungsverfahren dafür
|
|
US7098235B2
(en)
*
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
|
US20040110241A1
(en)
*
|
2002-12-06 |
2004-06-10 |
Segal Mark S. |
Materials and methods for monitoring vascular endothelial function
|
|
US20040198800A1
(en)
*
|
2002-12-19 |
2004-10-07 |
Geoffrey Allan |
Lipoxygenase inhibitors as hypolipidemic and anti-hypertensive agents
|
|
CA2510319A1
(en)
*
|
2002-12-20 |
2004-07-15 |
Thomas J. Smith |
High pressure compaction for pharmaceutical formulations
|
|
US20040132771A1
(en)
*
|
2002-12-20 |
2004-07-08 |
Pfizer Inc |
Compositions of choleseteryl ester transfer protein inhibitors and HMG-CoA reductase inhibitors
|
|
JP2006513186A
(ja)
|
2002-12-20 |
2006-04-20 |
ファイザー・プロダクツ・インク |
Cetp阻害剤およびhmg−coaレダクターゼ阻害剤を含む剤形
|
|
DE10261061A1
(de)
*
|
2002-12-24 |
2004-07-15 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Diätetisches Lebensmittel zur positiven Beeinflussung der kardiovaskulären Gesundheit
|
|
DE10261067A1
(de)
*
|
2002-12-24 |
2004-08-05 |
Nutrinova Nutrition Specialties & Food Ingredients Gmbh |
Cholesterinsenkendes Mittel, enthaltend eine n-3-Fettsäure
|
|
JP2006516620A
(ja)
*
|
2003-01-24 |
2006-07-06 |
ブリストル−マイヤーズ スクイブ カンパニー |
甲状腺受容体におけるシクロアルキル含有アニリドリガンド
|
|
TW200504021A
(en)
*
|
2003-01-24 |
2005-02-01 |
Bristol Myers Squibb Co |
Substituted anilide ligands for the thyroid receptor
|
|
EP1603548A4
(de)
*
|
2003-02-05 |
2007-10-10 |
Myriad Genetics Inc |
Verfahren und zusammensetzung zur behandlung neurodegenerativer erkrankungen
|
|
EP1452602A1
(de)
*
|
2003-02-25 |
2004-09-01 |
Antibiotic Co., |
Fermentatives Verfahren zur Herstellung von Pravastatin
|
|
US7557143B2
(en)
*
|
2003-04-18 |
2009-07-07 |
Bristol-Myers Squibb Company |
Thyroid receptor ligands
|
|
WO2004096278A1
(ja)
|
2003-04-28 |
2004-11-11 |
Sankyo Company, Limited |
アディポネクチン産生増強剤
|
|
WO2004096276A1
(ja)
*
|
2003-04-28 |
2004-11-11 |
Sankyo Company, Limited |
糖取り込み能増強剤
|
|
AR041089A1
(es)
|
2003-05-15 |
2005-05-04 |
Merck & Co Inc |
Procedimiento y composiciones farmaceutiicas para tratar aterosclerosis, dislipidemias y afecciones relacionadas
|
|
US7459474B2
(en)
*
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
|
KR100470078B1
(ko)
*
|
2003-06-12 |
2005-02-04 |
씨제이 주식회사 |
컴팩틴을 프라바스타틴으로 전환할 수 있는 스트렙토마이세스 종(Streptomyces sp.)CJPV 975652 및 그를 이용한 프라바스타틴의 제조방법
|
|
US7368468B2
(en)
*
|
2003-06-18 |
2008-05-06 |
Teva Pharmaceutical Industries Ltd. |
Fluvastatin sodium crystal forms XIV, LXXIII, LXXIX, LXXX and LXXXVII, processes for preparing them, compositions containing them and methods of using them
|
|
EP1790634A3
(de)
*
|
2003-06-18 |
2007-06-13 |
Teva Pharmaceutical Industries Ltd. |
Fluvastatin-natrium im Kristallform und Verfahren zu dessen Herstellung
|
|
WO2005007110A2
(en)
*
|
2003-07-11 |
2005-01-27 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods for hydrophobic drug delivery
|
|
WO2005065069A2
(en)
*
|
2003-07-11 |
2005-07-21 |
Myriad Genetics, Inc. |
Pharmaceutical methods, dosing regimes and dosage forms for the treatment of alzheimer's disease
|
|
US20050037063A1
(en)
*
|
2003-07-21 |
2005-02-17 |
Bolton Anthony E. |
Combined therapies
|
|
US6995183B2
(en)
*
|
2003-08-01 |
2006-02-07 |
Bristol Myers Squibb Company |
Adamantylglycine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
CA2535359A1
(en)
|
2003-08-21 |
2005-03-03 |
Merck Frosst Canada Ltd. |
Cathepsin cysteine protease inhibitors
|
|
EP1510208A1
(de)
*
|
2003-08-22 |
2005-03-02 |
Fournier Laboratories Ireland Limited |
Metformin-Statin-Kombination enthaltende pharmazeutische Zusammensetzungen
|
|
EP1562912A2
(de)
*
|
2003-08-28 |
2005-08-17 |
Teva Pharmaceutical Industries Limited |
Verfahren zur herstellung von rosuvastatin-calcium
|
|
US7884106B2
(en)
|
2003-08-29 |
2011-02-08 |
Kowa Company, Ltd. |
Method of stabilizing lipid-rich plaque and method of preventing rupture thereof
|
|
US20050053664A1
(en)
*
|
2003-09-08 |
2005-03-10 |
Eliezer Zomer |
Co-administration of a polysaccharide with a chemotherapeutic agent for the treatment of cancer
|
|
US20050171207A1
(en)
*
|
2003-09-26 |
2005-08-04 |
Myriad Genetics, Incorporated |
Method and composition for combination treatment of neurodegenerative disorders
|
|
JP2007521324A
(ja)
*
|
2003-09-29 |
2007-08-02 |
エノス ファーマシューティカルズ, インク. |
徐放性l−アルギニン調合物並びにその製造法及び使用法
|
|
US8227434B1
(en)
|
2003-11-04 |
2012-07-24 |
H. Lee Moffitt Cancer Center & Research Institute, Inc. |
Materials and methods for treating oncological disorders
|
|
EP1680099B1
(de)
*
|
2003-11-07 |
2009-04-15 |
JJ Pharma, Inc. |
Hdl-verstärkende kombinationstherapie-komplexe
|
|
US20090110760A1
(en)
*
|
2003-11-07 |
2009-04-30 |
Toyo Shinyaku Co., Ltd. |
Lipometabolism improver containing pine bark extract
|
|
US7767828B2
(en)
*
|
2003-11-12 |
2010-08-03 |
Phenomix Corporation |
Methyl and ethyl substituted pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
US7317109B2
(en)
*
|
2003-11-12 |
2008-01-08 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
NZ547752A
(en)
*
|
2003-11-12 |
2009-12-24 |
Phenomix Corp |
Heterocyclic boronic acid compounds for inhibiting dipeptidyl peptidase-IV
|
|
US7576121B2
(en)
*
|
2003-11-12 |
2009-08-18 |
Phenomix Corporation |
Pyrrolidine compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
AU2004293013B2
(en)
|
2003-11-19 |
2011-04-28 |
Metabasis Therapeutics, Inc. |
Novel phosphorus-containing thyromimetics
|
|
PL1641447T3
(pl)
*
|
2003-11-24 |
2009-04-30 |
Teva Gyogyszergyar Zartkoerueen Muekoedoe Reszvenytarsasag |
Sposób oczyszczania prawastatyny
|
|
EP1601658A1
(de)
*
|
2003-11-24 |
2005-12-07 |
Teva Pharmaceutical Industries Limited |
Kristalline ammoniumsalze von rosuvastatin
|
|
EP1722780A4
(de)
*
|
2003-11-26 |
2008-12-17 |
Univ Duke |
Verfahren zur prävention oder behandlung von glaukom
|
|
CN1277826C
(zh)
*
|
2003-12-01 |
2006-10-04 |
叶红平 |
辉伐他汀及其合成方法和以辉伐他汀为原料药的制剂
|
|
CN1894221B
(zh)
*
|
2003-12-02 |
2012-08-08 |
特瓦制药工业有限公司 |
用于表征罗苏伐他汀的参照标准品
|
|
CA2548790A1
(en)
*
|
2003-12-17 |
2005-06-30 |
Dainippon Sumitomo Pharma Co., Ltd. |
Medicinal compositions and combinations
|
|
WO2005062824A2
(en)
|
2003-12-23 |
2005-07-14 |
Merck & Co., Inc. |
Anti-hypercholesterolemic compounds
|
|
US20070179166A1
(en)
*
|
2003-12-24 |
2007-08-02 |
Valerie Niddam-Hildesheim |
Process for preparation of statins with high syn to anti ratio
|
|
US7851624B2
(en)
*
|
2003-12-24 |
2010-12-14 |
Teva Pharamaceutical Industries Ltd. |
Triol form of rosuvastatin and synthesis of rosuvastatin
|
|
CA2550742A1
(en)
*
|
2003-12-24 |
2005-07-14 |
Teva Pharmaceutical Industries Ltd. |
Process for preparation of statins with high syn to anti ratio
|
|
US20070161700A1
(en)
*
|
2004-12-28 |
2007-07-12 |
Kowa Company, Ltd. |
Inhibitor for the formation of y-secretase complex
|
|
US8163797B2
(en)
*
|
2003-12-31 |
2012-04-24 |
Actavis Elizabeth Llc |
Method of treating with stable pravastatin formulation
|
|
TWI252253B
(en)
*
|
2004-01-09 |
2006-04-01 |
Chinese Petroleum Corp |
A novel Pseudonocardia sp RMRC PAH4 and a process for bioconverting compactin into pravastatin using the same
|
|
US8158362B2
(en)
*
|
2005-03-30 |
2012-04-17 |
Decode Genetics Ehf. |
Methods of diagnosing susceptibility to myocardial infarction and screening for an LTA4H haplotype
|
|
US20100216863A1
(en)
*
|
2004-01-30 |
2010-08-26 |
Decode Genetics Ehf. |
Susceptibility Gene for Myocardial Infarction, Stroke, and PAOD; Methods of Treatment
|
|
EP1563837A1
(de)
*
|
2004-02-03 |
2005-08-17 |
Ferrer Internacional, S.A. |
Hypocholesterolämische Zusammensetzungen enthaltend ein Statin und ein Antiflatulenzmittel
|
|
WO2005079314A2
(en)
*
|
2004-02-13 |
2005-09-01 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods used to treat acne and candida
|
|
US8309574B2
(en)
*
|
2004-02-25 |
2012-11-13 |
Kowa Company, Ltd. |
Nuclear transfer promoter for Rac protein and method of screening the same
|
|
JP4728226B2
(ja)
*
|
2004-02-25 |
2011-07-20 |
興和株式会社 |
Cdc42タンパク質の核内移行促進剤及びそのスクリーニング方法
|
|
AU2005221656B2
(en)
|
2004-03-05 |
2011-06-23 |
The Trustees Of The University Of Pennsylvania |
Methods for treating disorders or diseases associated with hyperlipidemia and hypercholesterolemia while minimizing side-effects
|
|
US20060211752A1
(en)
|
2004-03-16 |
2006-09-21 |
Kohn Leonard D |
Use of phenylmethimazoles, methimazole derivatives, and tautomeric cyclic thiones for the treatment of autoimmune/inflammatory diseases associated with toll-like receptor overexpression
|
|
US20070258969A1
(en)
*
|
2004-03-19 |
2007-11-08 |
Eliezer Zomer |
Compositions and methods for targeting metastatic tumors using multivalent ligand-linked carbohydrate polymers
|
|
ATE414071T1
(de)
*
|
2004-03-30 |
2008-11-15 |
Lupin Ltd |
Verbessertes verfahren zur herstellung von 4- hydroxypyran-2-onderivaten
|
|
EP1731147A4
(de)
*
|
2004-03-31 |
2010-06-30 |
Kowa Co |
Topisches präparat
|
|
KR100598326B1
(ko)
|
2004-04-10 |
2006-07-10 |
한미약품 주식회사 |
HMG-CoA 환원효소 억제제의 경구투여용 서방형 제제및 이의 제조방법
|
|
WO2006001877A2
(en)
*
|
2004-04-13 |
2006-01-05 |
Myriad Genetics, Inc. |
Combination treatment for neurodegenerative disorders comprising r-flurbiprofen
|
|
AU2005247195A1
(en)
*
|
2004-05-27 |
2005-12-08 |
Dexcel Pharma Technologies Ltd |
Localized controlled absorption of statins in the gastrointestinal tract for achieving high blood levels of statins
|
|
US7803838B2
(en)
*
|
2004-06-04 |
2010-09-28 |
Forest Laboratories Holdings Limited |
Compositions comprising nebivolol
|
|
UA87854C2
(en)
|
2004-06-07 |
2009-08-25 |
Мерк Энд Ко., Инк. |
N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators
|
|
US7145040B2
(en)
*
|
2004-07-02 |
2006-12-05 |
Bristol-Myers Squibb Co. |
Process for the preparation of amino acids useful in the preparation of peptide receptor modulators
|
|
US20070021346A1
(en)
*
|
2005-05-26 |
2007-01-25 |
Ewing William R |
N-terminally modified GLP-1 receptor modulators
|
|
TW200611704A
(en)
*
|
2004-07-02 |
2006-04-16 |
Bristol Myers Squibb Co |
Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions
|
|
US7534763B2
(en)
|
2004-07-02 |
2009-05-19 |
Bristol-Myers Squibb Company |
Sustained release GLP-1 receptor modulators
|
|
US7786163B2
(en)
*
|
2004-07-12 |
2010-08-31 |
Forest Laboratories Holdings Limited (BM) |
Constrained cyano compounds
|
|
CA2573857A1
(en)
*
|
2004-07-13 |
2006-02-16 |
Teva Pharmaceutical Industries Ltd. |
A process for the preparation of rosuvastatin involving a tempo-mediated oxidation step
|
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
|
KR100637762B1
(ko)
*
|
2004-07-30 |
2006-10-23 |
주식회사 지니스 |
저콜레스테롤 란을 생산하기 위한 가금류용 사료첨가제 및 이를 이용한 저콜레스테롤 란의 생산방법
|
|
US20110217412A1
(en)
*
|
2004-07-30 |
2011-09-08 |
Jinis Biopharmaceuticals Co. |
Cholesterol lowering supplement and low cholesterol egg produced by using the same
|
|
WO2006017417A2
(en)
*
|
2004-08-02 |
2006-02-16 |
Pro-Pharmaceuticals, Inc. |
Compositions and methods for the enhancement of chemotherapy with microbial cytotoxins
|
|
US20090042979A1
(en)
*
|
2004-08-06 |
2009-02-12 |
Transform Pharmaceuticals Inc. |
Novel Statin Pharmaceutical Compositions and Related Methods of Treatment
|
|
NZ552390A
(en)
*
|
2004-08-06 |
2010-01-29 |
Transform Pharmaceuticals Inc |
Novel fenofibrate formulations and related methods of treatment
|
|
EP1786414A4
(de)
*
|
2004-08-06 |
2008-04-09 |
Transform Pharmaceuticals Inc |
Neue pharmazeutische statin-zusammensetzungen und relevante behandlungsverfahren
|
|
WO2006020852A2
(en)
*
|
2004-08-11 |
2006-02-23 |
Myriad Genetics, Inc. |
Pharmaceutical composition and method for treating neurodegenerative disorders
|
|
WO2006020850A2
(en)
*
|
2004-08-11 |
2006-02-23 |
Myriad Genetics, Inc. |
Pharmaceutical composition and method for treating neurodegenerative disorders
|
|
WO2006020853A2
(en)
*
|
2004-08-11 |
2006-02-23 |
Myriad Genetics, Inc. |
Pharmaceutical composition and method for treating neurodegenerative disorders
|
|
US20070244107A1
(en)
*
|
2004-08-25 |
2007-10-18 |
Waters M Gerard |
Method of Treating Atherosclerosis, Dyslipidemias and Related Conditions
|
|
US20060058261A1
(en)
*
|
2004-09-15 |
2006-03-16 |
Andre Aube |
Chitin derivatives for hyperlipidemia
|
|
AR051446A1
(es)
*
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
|
AU2005294165B2
(en)
|
2004-10-06 |
2012-02-02 |
The Brigham And Women's Hospital, Inc. |
Relevance of achieved levels of markers of systemic inflammation following treatment
|
|
US7517991B2
(en)
*
|
2004-10-12 |
2009-04-14 |
Bristol-Myers Squibb Company |
N-sulfonylpiperidine cannabinoid receptor 1 antagonists
|
|
MX2007005129A
(es)
*
|
2004-10-27 |
2007-09-11 |
Daiichi Sankyo Co Ltd |
Compuesto de benceno que tiene 2 o mas sustituyentes.
|
|
US20090196889A1
(en)
*
|
2004-11-22 |
2009-08-06 |
Dexcel Pharma Technologies Ltd. |
Controlled absorption of statins in the intestine
|
|
TWI307360B
(en)
|
2004-12-03 |
2009-03-11 |
Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag |
Process for constructing strain having compactin hydroxylation ability
|
|
WO2006062876A2
(en)
|
2004-12-09 |
2006-06-15 |
Merck & Co., Inc. |
Estrogen receptor modulators
|
|
TW200619204A
(en)
*
|
2004-12-10 |
2006-06-16 |
Kowa Co |
Method for reduction, stabilization and prevention of rupture of lipid rich plaque
|
|
US7816347B2
(en)
*
|
2004-12-15 |
2010-10-19 |
Solvay Pharmaceuticals Gmbh |
Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous endothelin producing system and HMG CoA reductase inhibitors
|
|
US7635699B2
(en)
*
|
2004-12-29 |
2009-12-22 |
Bristol-Myers Squibb Company |
Azolopyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7589088B2
(en)
*
|
2004-12-29 |
2009-09-15 |
Bristol-Myers Squibb Company |
Pyrimidine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
CN101098700A
(zh)
*
|
2005-01-06 |
2008-01-02 |
默克公司 |
治疗炎性疾病的药物组合疗法和药用组合物
|
|
WO2006076568A2
(en)
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Thiazolopyridines as cannabinoid receptor modulators
|
|
WO2006076598A2
(en)
*
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
WO2006076597A1
(en)
*
|
2005-01-12 |
2006-07-20 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
US20060160850A1
(en)
*
|
2005-01-18 |
2006-07-20 |
Chongqing Sun |
Bicyclic heterocycles as cannabinoid receptor modulators
|
|
CA2596426A1
(en)
*
|
2005-01-31 |
2006-08-10 |
Mylan Laboratories, Inc. |
Pharmaceutical composition comprising hydroxylated nebivolol
|
|
CN101115706A
(zh)
*
|
2005-02-09 |
2008-01-30 |
特瓦药厂私人有限公司 |
制备普伐他汀钠的方法
|
|
ES2319461T3
(es)
*
|
2005-02-10 |
2009-05-07 |
Bristol-Myers Squibb Company |
Dihidroquinazolinonas como moduladores de 5ht.
|
|
US20070037979A1
(en)
*
|
2005-02-22 |
2007-02-15 |
Valerie Niddam-Hildesheim |
Preparation of rosuvastatin
|
|
US20070167625A1
(en)
*
|
2005-02-22 |
2007-07-19 |
Anna Balanov |
Preparation of rosuvastatin
|
|
MX2007010138A
(es)
*
|
2005-02-22 |
2007-09-27 |
Teva Pharma |
Preparacion de rosuvastatina.
|
|
US20070293535A1
(en)
*
|
2005-02-24 |
2007-12-20 |
Kowa Company, Ltd. |
Nuclear Transfer Promoter for Ddc42 Protein and Method of Screening the Dame
|
|
AU2006302797B2
(en)
|
2005-03-02 |
2012-02-02 |
Merck Canada Inc. |
Composition for inhibition of cathepsin K
|
|
AU2006228525A1
(en)
*
|
2005-03-28 |
2006-10-05 |
Dexcel Pharma Technologies Ltd. |
Controlled absorption of statins in the intestine
|
|
EP2527337A1
(de)
|
2005-04-14 |
2012-11-28 |
Bristol-Myers Squibb Company |
Hemmer des 11-Beta-Hydroxysteroid-Dehydrogenase-1-Enzyms
|
|
EP1888050B1
(de)
|
2005-05-17 |
2012-03-21 |
Merck Sharp & Dohme Ltd. |
Cis-4-[(4-chlorophenyl)sulfonyl]-4-(2,5-difluorophenyl)cyclohexanepropansäure zur Behandlug von Krebs
|
|
US7521557B2
(en)
|
2005-05-20 |
2009-04-21 |
Bristol-Myers Squibb Company |
Pyrrolopyridine-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US7825139B2
(en)
*
|
2005-05-25 |
2010-11-02 |
Forest Laboratories Holdings Limited (BM) |
Compounds and methods for selective inhibition of dipeptidyl peptidase-IV
|
|
US20060275356A1
(en)
*
|
2005-05-25 |
2006-12-07 |
Burgess James W |
Pharmaceutical compositions for treating or preventing coronary artery disease
|
|
CA2610694A1
(en)
|
2005-05-31 |
2006-12-07 |
Mylan Laboratories, Inc. |
Compositions comrising nebivolol
|
|
TW200726765A
(en)
*
|
2005-06-17 |
2007-07-16 |
Bristol Myers Squibb Co |
Triazolopyridine cannabinoid receptor 1 antagonists
|
|
US7452892B2
(en)
*
|
2005-06-17 |
2008-11-18 |
Bristol-Myers Squibb Company |
Triazolopyrimidine cannabinoid receptor 1 antagonists
|
|
US7317012B2
(en)
*
|
2005-06-17 |
2008-01-08 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoind-1 receptor modulators
|
|
US7629342B2
(en)
*
|
2005-06-17 |
2009-12-08 |
Bristol-Myers Squibb Company |
Azabicyclic heterocycles as cannabinoid receptor modulators
|
|
US7632837B2
(en)
*
|
2005-06-17 |
2009-12-15 |
Bristol-Myers Squibb Company |
Bicyclic heterocycles as cannabinoid-1 receptor modulators
|
|
US20060287342A1
(en)
*
|
2005-06-17 |
2006-12-21 |
Mikkilineni Amarendra B |
Triazolopyrimidine heterocycles as cannabinoid receptor modulators
|
|
KR20080028964A
(ko)
|
2005-06-27 |
2008-04-02 |
엑셀리시스, 인코포레이티드 |
피라졸계 lxr 변조제
|
|
US20070015832A1
(en)
*
|
2005-07-14 |
2007-01-18 |
Myriad Genetics, Incorporated |
Methods of treating overactive bladder and urinary incontinence
|
|
KR20080034171A
(ko)
*
|
2005-07-28 |
2008-04-18 |
브리스톨-마이어스 스큅 컴퍼니 |
세로토닌 수용체 효능제 및 길항제로서의 치환된테트라히드로-1h-피리도[4,3,b]인돌
|
|
RU2008108078A
(ru)
*
|
2005-08-04 |
2009-09-10 |
Трансформ Фармасьютикалз, Инк. (Us) |
Новые препаративные формы, включающие фенофибрат и статин, и соответствующие способы лечения
|
|
TW200800917A
(en)
*
|
2005-08-16 |
2008-01-01 |
Teva Pharma |
Crystalline rosuvastatin intermediate
|
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
|
TW200804345A
(en)
*
|
2005-08-30 |
2008-01-16 |
Novartis Ag |
Substituted benzimidazoles and methods of preparation
|
|
WO2007030302A2
(en)
*
|
2005-09-01 |
2007-03-15 |
Prescient Medical, Inc. |
Drugs coated on a device to treat vulnerable plaque
|
|
US20090297496A1
(en)
*
|
2005-09-08 |
2009-12-03 |
Childrens Hospital Medical Center |
Lysosomal Acid Lipase Therapy for NAFLD and Related Diseases
|
|
US20080139457A1
(en)
*
|
2005-09-16 |
2008-06-12 |
Virginia Commonwealth University |
Therapeutic compositions comprising chorionic gonadotropins and HMG CoA reductase inhibitors
|
|
US8119358B2
(en)
*
|
2005-10-11 |
2012-02-21 |
Tethys Bioscience, Inc. |
Diabetes-related biomarkers and methods of use thereof
|
|
DE102005049293A1
(de)
*
|
2005-10-15 |
2007-04-26 |
Bayer Healthcare Ag |
Kombinationspräparate von Salzen oder o-Acetylsalicylsäure
|
|
WO2007047725A2
(en)
*
|
2005-10-18 |
2007-04-26 |
Aegerion Pharmaceuticals |
Methods for treating disorders associated with hyperlipidemia in a mammal
|
|
US7741317B2
(en)
|
2005-10-21 |
2010-06-22 |
Bristol-Myers Squibb Company |
LXR modulators
|
|
AR056155A1
(es)
*
|
2005-10-26 |
2007-09-19 |
Bristol Myers Squibb Co |
Antagonistas del receptor 1 de la hormona de concentracion de melanina no basica
|
|
US7488725B2
(en)
|
2005-10-31 |
2009-02-10 |
Bristol-Myers Squibb Co. |
Pyrrolidinyl beta-amino amide-based inhibitors of dipeptidyl peptidase IV and methods
|
|
US8440695B2
(en)
*
|
2005-11-09 |
2013-05-14 |
St Jude Children's Research Hospital |
Use of chloroquine to treat metabolic syndrome
|
|
US7888376B2
(en)
|
2005-11-23 |
2011-02-15 |
Bristol-Myers Squibb Company |
Heterocyclic CETP inhibitors
|
|
CN101351551A
(zh)
*
|
2005-11-29 |
2009-01-21 |
协和发酵工业株式会社 |
新型蛋白质和编码该蛋白质的dna
|
|
US7592461B2
(en)
|
2005-12-21 |
2009-09-22 |
Bristol-Myers Squibb Company |
Indane modulators of glucocorticoid receptor, AP-1, and/or NF-κB activity and use thereof
|
|
EP1981849A1
(de)
*
|
2005-12-29 |
2008-10-22 |
LEK Pharmaceuticals D.D. |
Heterocyclische verbindungen
|
|
JP2009523177A
(ja)
*
|
2006-01-11 |
2009-06-18 |
ブリストル−マイヤーズ スクイブ カンパニー |
ヒトグルカゴン様ペプチド−1調節因子、並びに糖尿病および関連症状の治療におけるその使用
|
|
US7553836B2
(en)
*
|
2006-02-06 |
2009-06-30 |
Bristol-Myers Squibb Company |
Melanin concentrating hormone receptor-1 antagonists
|
|
GB0603041D0
(en)
|
2006-02-15 |
2006-03-29 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
|
CA2569776A1
(en)
*
|
2006-02-17 |
2007-08-17 |
Kos Life Sciences, Inc. |
Low flush niacin formulation
|
|
US20090069275A1
(en)
*
|
2006-02-17 |
2009-03-12 |
Rocca Jose G |
Low flush niacin formulation
|
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
|
MX2008013427A
(es)
|
2006-04-19 |
2008-11-04 |
Novartis Ag |
Compuestos de benzoxazole y benzotiazole sustituidos-6-0 y metodos para inhibir la señalizacion csf-1r.
|
|
WO2007124461A2
(en)
|
2006-04-20 |
2007-11-01 |
Amgen Inc. |
Glp-1 compounds
|
|
EP2012828A2
(de)
*
|
2006-04-28 |
2009-01-14 |
Resolvyx Pharmaceuticals, Inc. |
Zusammensetzungen und verfahren zur behandlung von herz-kreislauf-rkrankungen
|
|
US20070269503A1
(en)
*
|
2006-05-16 |
2007-11-22 |
James Walter Burgess |
Combinations of HMG CoA reductase inhibitors and negatively charged phospholipids and uses thereof
|
|
WO2007139589A1
(en)
|
2006-05-26 |
2007-12-06 |
Bristol-Myers Squibb Company |
Sustained release glp-1 receptor modulators
|
|
EP2030025A2
(de)
*
|
2006-06-07 |
2009-03-04 |
Tethys Bioscience, Inc. |
Mit arteriovaskulären ereignissen assoziierte marker und verfahren zu ihrer verwendung
|
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
|
US20080044326A1
(en)
*
|
2006-07-04 |
2008-02-21 |
Esencia Co., Ltd. |
Sterilizer for baby products
|
|
PT2363130E
(pt)
|
2006-07-05 |
2014-06-25 |
Takeda Gmbh |
Combinação de atorvastatina ou sinvastatina, inibidores de hmg-coa redutase, com um inibidor da fosfodiesterase 4, tal como roflumilaste, para o tratamento de doenças pulmonares inflamatórias
|
|
US20080033045A1
(en)
*
|
2006-07-07 |
2008-02-07 |
Myriad Genetics, Incorporated |
Treatment of psychiatric disorders
|
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
|
CN101511348B
(zh)
|
2006-08-30 |
2012-04-18 |
国立大学法人九州大学 |
含有包封他汀类之纳米颗粒的药物组合物
|
|
EP2083831B1
(de)
|
2006-09-22 |
2013-12-25 |
Merck Sharp & Dohme Corp. |
Verfahren zur behandlung von fettsäure-synthese-hemmern
|
|
US20080118572A1
(en)
*
|
2006-10-10 |
2008-05-22 |
Harold Richard Hellstrom |
Methods and compositions for reducing the risk of adverse cardiovascular events associated with the administration of artificial blood
|
|
WO2008044236A2
(en)
*
|
2006-10-10 |
2008-04-17 |
Dexcel Pharma Technologies Ltd. |
Improved release of statins in the intestine
|
|
EP2089355A2
(de)
|
2006-11-01 |
2009-08-19 |
Brystol-Myers Squibb Company |
Modulatoren der glucocorticoidrezeptor-, ap-1- und/oder nf-kappa-b-aktivität und deren verwendung
|
|
US20110218176A1
(en)
|
2006-11-01 |
2011-09-08 |
Barbara Brooke Jennings-Spring |
Compounds, methods, and treatments for abnormal signaling pathways for prenatal and postnatal development
|
|
AU2007338625A1
(en)
*
|
2006-12-21 |
2008-07-03 |
Aegerion Pharmaceuticals, Inc. |
Methods for treating obesity with a combination comprising a MTP inhibitor and a cholesterol absorption inhibitor
|
|
AR064777A1
(es)
|
2007-01-10 |
2009-04-22 |
Inst Di Reserche D Biolog Mole |
Indazoles sustituidos con amida como inhibidores de poli (adp- ribosa) polimerasa (parp)
|
|
WO2008106227A1
(en)
*
|
2007-03-01 |
2008-09-04 |
Concourse Health Sciences Llc |
Isomers of inositol niacinate and uses thereof
|
|
CA2679659C
(en)
|
2007-03-01 |
2016-01-19 |
Novartis Ag |
Pim kinase inhibitors and methods of their use
|
|
EP2134169A2
(de)
|
2007-03-09 |
2009-12-23 |
Indigene Pharmaceuticals Inc. |
Kombination von metformid-r-(+)-lipoat und antihyperlipidämika für die behandlung von diabetes-hyperglykämie und diabetesbedingte komplikationen
|
|
WO2008112887A1
(en)
*
|
2007-03-13 |
2008-09-18 |
Musc Foundation For Research Development |
Methods of treating juvenile type 1 diabetes mellitus
|
|
AR065809A1
(es)
|
2007-03-22 |
2009-07-01 |
Bristol Myers Squibb Co |
Formulaciones farmaceuticas que contienen un inhibidor sglt2
|
|
TWI407955B
(zh)
|
2007-03-29 |
2013-09-11 |
Kowa Co |
高脂血症之預防及/或治療劑
|
|
US20080249141A1
(en)
*
|
2007-04-06 |
2008-10-09 |
Palepu Nageswara R |
Co-therapy with and combinations of statins and 1,4-dihydropyridine-3,5-dicarboxydiesters
|
|
AU2008236616A1
(en)
*
|
2007-04-09 |
2008-10-16 |
Scidose, Llc |
Combinations of statins and anti-obesity agent
|
|
US20080249156A1
(en)
*
|
2007-04-09 |
2008-10-09 |
Palepu Nageswara R |
Combinations of statins and anti-obesity agent and glitazones
|
|
JP2010524953A
(ja)
|
2007-04-17 |
2010-07-22 |
ブリストル−マイヤーズ スクイブ カンパニー |
縮合ヘテロ環11−β−ヒドロキシステロイドデヒドロゲナーゼI型阻害剤
|
|
EP2541254B1
(de)
|
2007-04-18 |
2014-11-12 |
Health Diagnostic Laboratory, Inc. |
Diabetesassoziierte Biomarker und Verfahren zur deren Verwendung dafür
|
|
PE20090696A1
(es)
*
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
|
US20100086615A1
(en)
|
2007-04-27 |
2010-04-08 |
Kyushu University, National University Corporation |
Agent for treatment of pulmonary disease
|
|
JP2010528023A
(ja)
*
|
2007-05-18 |
2010-08-19 |
ブリストル−マイヤーズ スクイブ カンパニー |
Sglt2阻害剤の結晶構造およびその製造方法
|
|
MX2009012679A
(es)
|
2007-05-21 |
2009-12-11 |
Novartis Ag |
Inhibidores de csf-1r, composiciones y metodos de uso.
|
|
AU2008287542C1
(en)
|
2007-06-01 |
2015-01-22 |
The Trustees Of Princeton University |
Treatment of viral infections by modulation of host cell metabolic pathways
|
|
DE102007028320A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
AU2008266960A1
(en)
|
2007-06-20 |
2008-12-24 |
Merck Sharp & Dohme Corp. |
Diphenyl substituted alkanes
|
|
DE102007028319A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
DE102007028406A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
DE102007028407A1
(de)
|
2007-06-20 |
2008-12-24 |
Bayer Healthcare Ag |
Substituierte Oxazolidinone und ihre Verwendung
|
|
AU2008269154B2
(en)
|
2007-06-27 |
2014-06-12 |
Merck Sharp & Dohme Llc |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors
|
|
US20090011994A1
(en)
*
|
2007-07-06 |
2009-01-08 |
Bristol-Myers Squibb Company |
Non-basic melanin concentrating hormone receptor-1 antagonists and methods
|
|
JP2010534722A
(ja)
*
|
2007-07-27 |
2010-11-11 |
ブリストル−マイヤーズ スクイブ カンパニー |
新規グルコキナーゼ活性化薬およびその使用方法
|
|
US20090076148A1
(en)
*
|
2007-09-14 |
2009-03-19 |
Protia, Llc |
Deuterium-enriched pravastatin
|
|
JP5465177B2
(ja)
*
|
2007-09-20 |
2014-04-09 |
アイアールエム・リミテッド・ライアビリティ・カンパニー |
Gpr119活性のモジュレーターとしての化合物および組成物
|
|
US8309730B2
(en)
|
2007-11-01 |
2012-11-13 |
Bristol-Myers Squibb Company |
Nonsteroidal compounds useful as modulators of glucocorticoid receptor AP-1 and/or NF-kappab acitivity and use thereof
|
|
US20090163452A1
(en)
*
|
2007-12-20 |
2009-06-25 |
Schwartz Janice B |
Compositions and methods for lowering serum cholesterol
|
|
BRPI0821090B8
(pt)
|
2007-12-21 |
2021-05-25 |
Ligand Pharm Inc |
moduladores seletivos de receptores de androgênio (sarms) e uso do mesmo
|
|
US20090226516A1
(en)
*
|
2008-03-04 |
2009-09-10 |
Pharma Pass Ii Llc |
Sartan compositions
|
|
US20090226515A1
(en)
*
|
2008-03-04 |
2009-09-10 |
Pharma Pass Ii Llc |
Statin compositions
|
|
WO2009148709A1
(en)
*
|
2008-04-16 |
2009-12-10 |
University Of Utah Research Foundation |
Pharmacological targeting of vascular malformations
|
|
PE20091928A1
(es)
*
|
2008-05-29 |
2009-12-31 |
Bristol Myers Squibb Co |
Tienopirimidinas hidroxisustituidas como antagonistas de receptor-1 de hormona concentradora de melanina no basicos
|
|
ES2330184B1
(es)
|
2008-06-03 |
2010-07-05 |
Neuron Biopharma, S.A. |
Uso de estatinas como anticonvulsivantes, antiepilepticos y neuroprotectores.
|
|
EP2138178A1
(de)
|
2008-06-28 |
2009-12-30 |
Bayer Schering Pharma Aktiengesellschaft |
Oxazolidninone zur Behandlung der chronisch obstruktiven Lungenerkrankung (COPD) und/oder Asthma
|
|
EP2161024A1
(de)
|
2008-09-05 |
2010-03-10 |
Universitätsklinikum Hamburg-Eppendorf |
Kombinationspräparat zur Behandlung von Krebs
|
|
EP2341137B1
(de)
|
2008-10-06 |
2014-08-13 |
MicroBiopharm Japan Co., Ltd. |
Expressionsvektor für pseudonocardia autotrophica
|
|
WO2010093601A1
(en)
|
2009-02-10 |
2010-08-19 |
Metabasis Therapeutics, Inc. |
Novel sulfonic acid-containing thyromimetics, and methods for their use
|
|
AU2010229653A1
(en)
|
2009-03-27 |
2011-10-20 |
Astrazeneca Ab |
Methods for preventing major adverse cardiovascular events with DPP-IV inhibitors
|
|
US8691825B2
(en)
|
2009-04-01 |
2014-04-08 |
Merck Sharp & Dohme Corp. |
Inhibitors of AKT activity
|
|
TW201039815A
(en)
|
2009-04-13 |
2010-11-16 |
Resolvyx Pharmaceuticals Inc |
Compositions and methods for the treatment of inflammation
|
|
US8470805B2
(en)
*
|
2009-04-30 |
2013-06-25 |
Kaohsiung Medical University |
Processes for preparing piperazinium salts of KMUP and use thereof
|
|
CA2761934C
(en)
|
2009-05-28 |
2018-01-09 |
Exelixis Patent Company Llc |
Substituted 1-(biphenyl-4-yl)-2-benzyl-4-hydroxyalkyl-1h-imidazole compounds and their use as lxr modulators
|
|
WO2011014520A2
(en)
|
2009-07-29 |
2011-02-03 |
Irm Llc |
Compounds and compositions as modulators of gpr119 activity
|
|
MX2012004078A
(es)
|
2009-10-09 |
2012-07-25 |
Irm Llc |
Compuestos y composiciones como moduladores de la actividad de gpr119.
|
|
AU2010307198B9
(en)
|
2009-10-14 |
2014-02-13 |
Merck Sharp & Dohme Corp. |
Substituted piperidines that increase p53 activity and the uses thereof
|
|
RU2558798C2
(ru)
|
2009-11-13 |
2015-08-10 |
Астразенека Аб |
Составы таблетки с немедленным высвобождением
|
|
CN102711738A
(zh)
|
2009-11-13 |
2012-10-03 |
百时美施贵宝公司 |
质量得以减小的二甲双胍制剂
|
|
LT2498758T
(lt)
|
2009-11-13 |
2018-11-26 |
Astrazeneca Ab |
Dvisluoksnės tabletės formuluotės
|
|
US8394858B2
(en)
|
2009-12-03 |
2013-03-12 |
Novartis Ag |
Cyclohexane derivatives and uses thereof
|
|
US20130115622A1
(en)
|
2009-12-14 |
2013-05-09 |
Kyoto University |
Pharmaceutical composition for prevention and treatment of amyotrophic lateral sclerosis
|
|
KR20120139723A
(ko)
|
2010-02-01 |
2012-12-27 |
더 호스피탈 포 식 칠드런 |
재발협착증의 치료 및 예방을 위한 원격 허혈 처치
|
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
|
CN102939054A
(zh)
|
2010-03-31 |
2013-02-20 |
儿童医院 |
远端缺血处理改进心肌梗死之后的结果的用途
|
|
CA2800520A1
(en)
|
2010-04-08 |
2011-10-13 |
The Hospital For Sick Children |
Use of remote ischemic conditioning for traumatic injury
|
|
EP2558461B1
(de)
|
2010-04-14 |
2015-12-02 |
Bristol-Myers Squibb Company |
Neuartige glucokinase-aktivatoren und verfahren zu ihrer verwendung
|
|
US8372877B2
(en)
|
2010-04-16 |
2013-02-12 |
Cumberland Pharmaceuticals |
Stabilized statin formulations
|
|
EP2571860A1
(de)
|
2010-05-21 |
2013-03-27 |
Pfizer Inc |
2-phenyl-benzoylamide
|
|
EP2584903B1
(de)
|
2010-06-24 |
2018-10-24 |
Merck Sharp & Dohme Corp. |
Neue heterozyklische verbindungen als erk-hemmer
|
|
WO2012006398A2
(en)
|
2010-07-09 |
2012-01-12 |
Bhv Pharma, Inc. |
Combination immediate/delayed release delivery system for short half-life pharmaceuticals including remogliflozin
|
|
US8697739B2
(en)
|
2010-07-29 |
2014-04-15 |
Novartis Ag |
Bicyclic acetyl-CoA carboxylase inhibitors and uses thereof
|
|
JP6043285B2
(ja)
|
2010-08-02 |
2016-12-14 |
サーナ・セラピューティクス・インコーポレイテッドSirna Therapeutics,Inc. |
低分子干渉核酸(siNA)を用いたカテニン(カドヘリン結合型タンパク質)β1(CTNNB1)遺伝子発現のRNA干渉媒介性阻害
|
|
LT2606134T
(lt)
|
2010-08-17 |
2019-07-25 |
Sirna Therapeutics, Inc. |
Hepatito b viruso (hbv) geno raiškos slopinimas, tarpininkaujant rnr interferencijai naudojant mažą interferuojančią nukleorūgštį (sina)
|
|
EP2608669B1
(de)
|
2010-08-23 |
2016-06-22 |
Merck Sharp & Dohme Corp. |
Neue pyrazolo-[1,5-a-]pyrimidinderivate als mtor-hemmer
|
|
US8946216B2
(en)
|
2010-09-01 |
2015-02-03 |
Merck Sharp & Dohme Corp. |
Indazole derivatives useful as ERK inhibitors
|
|
EP2615916B1
(de)
|
2010-09-16 |
2017-01-04 |
Merck Sharp & Dohme Corp. |
Kondensierte pyrazolderivate als neue erk-hemmer
|
|
WO2012046772A1
(ja)
|
2010-10-06 |
2012-04-12 |
国立大学法人東京大学 |
リンパ浮腫予防治療剤
|
|
WO2012058210A1
(en)
|
2010-10-29 |
2012-05-03 |
Merck Sharp & Dohme Corp. |
RNA INTERFERENCE MEDIATED INHIBITION OF GENE EXPRESSION USING SHORT INTERFERING NUCLEIC ACIDS (siNA)
|
|
TWI462739B
(zh)
|
2010-11-02 |
2014-12-01 |
Univ Kaohsiung Medical |
Sildenafil-同族物四級銨哌嗪鹽類之製備及醫療用途
|
|
EP2654748B1
(de)
|
2010-12-21 |
2016-07-27 |
Merck Sharp & Dohme Corp. |
Indazolderivate als erk-hemmer
|
|
WO2012085191A1
(en)
|
2010-12-23 |
2012-06-28 |
Dsm Sinochem Pharmaceuticals Netherlands B.V. |
Crystalline form of pravastatine and process for the preparation thereof
|
|
TWI631963B
(zh)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
包含鈉-葡萄糖共同輸送體1與2之抑制劑的組合物與應用方法
|
|
EP2665707B1
(de)
|
2011-01-20 |
2017-01-18 |
Merck Sharp & Dohme Corp. |
Mineralkortikoid-rezeptorantagonisten
|
|
JP2014504610A
(ja)
|
2011-01-31 |
2014-02-24 |
カディラ ヘルスケア リミテッド |
脂肪異栄養症の処置
|
|
US8791162B2
(en)
|
2011-02-14 |
2014-07-29 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
US20130345392A1
(en)
|
2011-03-04 |
2013-12-26 |
Pfizer Inc |
Edn3-like peptides and uses thereof
|
|
TW201242953A
(en)
|
2011-03-25 |
2012-11-01 |
Bristol Myers Squibb Co |
Imidazole prodrug LXR modulators
|
|
WO2012139495A1
(en)
|
2011-04-13 |
2012-10-18 |
Merck Sharp & Dohme Corp. |
Mineralocorticoid receptor antagonists
|
|
EP2699568A1
(de)
|
2011-04-21 |
2014-02-26 |
Piramal Enterprises Limited |
Kristalline form eines morpholinsulfonylindolderivat-salzes und verfahren zu seiner herstellung
|
|
WO2013055606A1
(en)
|
2011-10-13 |
2013-04-18 |
Merck Sharp & Dohme Corp. |
Mineralocorticoid receptor antagonists
|
|
EP2770987B1
(de)
|
2011-10-27 |
2018-04-04 |
Merck Sharp & Dohme Corp. |
Neue verbindungen als erk-hemmer
|
|
KR101466617B1
(ko)
|
2011-11-17 |
2014-11-28 |
한미약품 주식회사 |
오메가-3 지방산 및 HMG-CoA 환원효소 억제제를 포함하는 안정성이 증가된 경구용 복합 제제
|
|
WO2013102193A1
(en)
|
2011-12-29 |
2013-07-04 |
Trustees Of Tufts College |
Functionalization of biomaterials to control regeneration and inflammation responses
|
|
AU2013214693B2
(en)
|
2012-02-02 |
2017-02-23 |
Kenneth Gek-Jin OOI |
Improvements in tear film stability
|
|
EP3453762B1
(de)
|
2012-05-02 |
2021-04-21 |
Sirna Therapeutics, Inc. |
Sina-zusammensetzungen
|
|
SI2847228T1
(sl)
|
2012-05-10 |
2018-11-30 |
Bayer Pharma Aktiengesellschaft |
Protitelesa zmožna vezave na faktor koagulacije XI in/ali njeno aktivirano obliko faktor XIa in njihove uporabe
|
|
RU2654484C1
(ru)
|
2012-05-11 |
2018-05-21 |
Ресет Терапьютикс, Инк. |
Карбазолсодержащие сульфонамиды в качестве модуляторов криптохрома
|
|
CA2881563C
(en)
|
2012-08-01 |
2021-07-20 |
Zahra TAVAKOLI |
Free flowing, frozen compositions comprising a therapeutic agent
|
|
US8729092B2
(en)
|
2012-09-24 |
2014-05-20 |
Terence J. Scallen |
Rosuvastatin enantiomer compounds
|
|
WO2014052619A1
(en)
|
2012-09-27 |
2014-04-03 |
Irm Llc |
Piperidine derivatives and compositions as modulators of gpr119 activity
|
|
EP2900241B1
(de)
|
2012-09-28 |
2018-08-08 |
Merck Sharp & Dohme Corp. |
Neuartige verbindungen als erk-hemmer
|
|
CA2891773C
(en)
|
2012-11-20 |
2021-01-19 |
Lexicon Pharmaceuticals, Inc. |
Inhibitors of sodium glucose cotransporter 1
|
|
AU2013352568B2
(en)
|
2012-11-28 |
2019-09-19 |
Merck Sharp & Dohme Llc |
Compositions and methods for treating cancer
|
|
ES2707305T3
(es)
|
2012-12-20 |
2019-04-03 |
Merck Sharp & Dohme |
Imidazopiridinas sustituidas como inhibidores de HDM2
|
|
US9540377B2
(en)
|
2013-01-30 |
2017-01-10 |
Merck Sharp & Dohme Corp. |
2,6,7,8 substituted purines as HDM2 inhibitors
|
|
EP2968275B1
(de)
|
2013-03-15 |
2017-11-29 |
Bristol-Myers Squibb Company |
Lxr-modulatoren
|
|
TWI686213B
(zh)
|
2013-03-21 |
2020-03-01 |
美商優普順藥物公司美國分部 |
可注射持續釋放組合物及使用其治療關節之發炎及與發炎有關之疼痛之方法
|
|
BR112015026513A2
(pt)
|
2013-04-17 |
2017-07-25 |
Pfizer |
derivados de n-piperidin-3-ilbenzamida para tratar as doenças cardiovasculares
|
|
US20160166539A1
(en)
|
2013-04-22 |
2016-06-16 |
Cadila Healthcare Limited |
A novel composition for nonalcoholic fatty liver disease (nafld)
|
|
ES2889916T3
(es)
|
2013-05-30 |
2022-01-14 |
Cadila Healthcare Ltd |
Un procedimiento para la preparación de pirroles con actividades hipolipidémicas e hipocolesterémicas
|
|
TW201636015A
(zh)
|
2013-07-05 |
2016-10-16 |
卡地拉保健有限公司 |
協同性組成物
|
|
IN2013MU02470A
(de)
|
2013-07-25 |
2015-06-26 |
Cadila Healthcare Ltd |
|
|
WO2015027021A1
(en)
|
2013-08-22 |
2015-02-26 |
Bristol-Myers Squibb Company |
Imide and acylurea derivatives as modulators of the glucocorticoid receptor
|
|
EP3041938A1
(de)
|
2013-09-03 |
2016-07-13 |
Moderna Therapeutics, Inc. |
Kreisförmige polynukleotide
|
|
IN2013MU02905A
(de)
|
2013-09-06 |
2015-07-03 |
Cadila Healthcare Ltd |
|
|
RU2692799C2
(ru)
|
2013-10-08 |
2019-06-27 |
Мерк Шарп И Доум Корп. |
Ингибиторы цистеинпротеаз катепсинов
|
|
WO2015051479A1
(en)
|
2013-10-08 |
2015-04-16 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
JP6536871B2
(ja)
|
2013-12-02 |
2019-07-03 |
国立大学法人京都大学 |
Fgfr3病の予防および治療剤ならびにそのスクリーニング方法
|
|
EP3094323A4
(de)
|
2014-01-17 |
2017-10-11 |
Ligand Pharmaceuticals Incorporated |
Verfahren und zusammensetzungen zur modulierung von hormonspiegeln
|
|
WO2015120580A1
(en)
|
2014-02-11 |
2015-08-20 |
Merck Sharp & Dohme Corp. |
Cathepsin cysteine protease inhibitors
|
|
TWI690521B
(zh)
|
2014-04-07 |
2020-04-11 |
美商同步製藥公司 |
作為隱花色素調節劑之含有咔唑之醯胺類、胺基甲酸酯類及脲類
|
|
CA2950390C
(en)
|
2014-05-30 |
2020-09-22 |
Pfizer Inc. |
Carbonitrile derivatives as selective androgen receptor modulators
|
|
JO3589B1
(ar)
|
2014-08-06 |
2020-07-05 |
Novartis Ag |
مثبطات كيناز البروتين c وطرق استخداماتها
|
|
WO2016044021A1
(en)
|
2014-09-15 |
2016-03-24 |
The Board Of Trustees Of The Leland Stanford Junior University |
Targeting aneurysm disease by modulating phagocytosis pathways
|
|
WO2016055901A1
(en)
|
2014-10-08 |
2016-04-14 |
Pfizer Inc. |
Substituted amide compounds
|
|
EP4218812A1
(de)
|
2015-02-27 |
2023-08-02 |
The Board of Trustees of the Leland Stanford Junior University |
Kombinationstherapie zur behandlung von atherosklerose
|
|
EP3288584A2
(de)
|
2015-04-30 |
2018-03-07 |
President and Fellows of Harvard College |
Anti-ap2-antikörper und antigenbindemittel zur behandlung von stoffwechselerkrankungen
|
|
US10385017B2
(en)
|
2015-10-14 |
2019-08-20 |
Cadila Healthcare Limited |
Pyrrole compound, compositions and process for preparation thereof
|
|
JP2018531951A
(ja)
|
2015-10-27 |
2018-11-01 |
ユープラシア ファーマシューティカルズ インク. |
局所麻酔薬の徐放性製剤
|
|
WO2018071283A1
(en)
|
2016-10-12 |
2018-04-19 |
Merck Sharp & Dohme Corp. |
Kdm5 inhibitors
|
|
WO2018104916A1
(en)
|
2016-12-09 |
2018-06-14 |
Cadila Healthcare Limited |
Treatment for primary biliary cholangitis
|
|
US20180346577A1
(en)
|
2017-05-30 |
2018-12-06 |
The Board Of Trustees Of The Leland Stanford Junior University |
Treatment of neuroinflammatory disease
|
|
US11098059B2
(en)
|
2017-11-08 |
2021-08-24 |
Merck Sharp & Dohme Corp. |
PRMT5 inhibitors
|
|
WO2019094311A1
(en)
|
2017-11-08 |
2019-05-16 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
US20210290598A1
(en)
|
2018-05-08 |
2021-09-23 |
National University Corporation Okayama University |
Medicament useful for cardiovascular disease
|
|
PE20210644A1
(es)
|
2018-07-19 |
2021-03-23 |
Astrazeneca Ab |
METODOS DE TRATAMIENTO DE HFpEF EMPLEANDO DAPAGLIFLOZINA Y COMPOSICIONES QUE COMPRENDEN LA MISMA
|
|
WO2020017575A1
(ja)
|
2018-07-19 |
2020-01-23 |
国立大学法人京都大学 |
多能性幹細胞由来の板状軟骨およびその製造方法
|
|
WO2020033284A1
(en)
|
2018-08-07 |
2020-02-13 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
US12173026B2
(en)
|
2018-08-07 |
2024-12-24 |
Merck Sharp & Dohme Llc |
PRMT5 inhibitors
|
|
US12552826B2
(en)
|
2018-08-07 |
2026-02-17 |
Merck Sharp & Dohme Llc |
PRMT5 inhibitors
|
|
US11993602B2
(en)
|
2018-08-07 |
2024-05-28 |
Merck Sharp & Dohme Llc |
PRMT5 inhibitors
|
|
CA3113037A1
(en)
|
2018-09-26 |
2020-04-02 |
Lexicon Pharmaceuticals, Inc. |
Crystalline forms of n-(1-((2-(dimethylamino)ethyl)amino)-2-methyl-1-oopropan-2-yl)-4-(4-(2-methyl-5-(2s,3r,4r,5s,6r)-3,4,5-trihydroxy-6-(methylthio)tetrahydro-2h-pyran-2-yl)benzyl)phenl)butanamide and methods of their synthesis
|
|
EP3900787A4
(de)
|
2018-12-21 |
2022-02-23 |
Kyoto University |
Lubricin-lokalisiertes knorpelähnliches gewebe, verfahren zur herstellung davon und zusammensetzung damit zur behandlung von gelenkknorpelschäden
|
|
CR20210441A
(es)
|
2019-01-18 |
2022-03-11 |
Astrazeneca Ab |
Inhibidores de la pcsk9 y métodos de uso de los mismos
|
|
MX2021010987A
(es)
|
2019-03-13 |
2021-12-15 |
National Univ Corporation Hamamatsu Univ School Of Medicine |
Composicion farmaceutica para el tratamiento contra aneurisma aortico.
|
|
EP3956309A4
(de)
|
2019-04-19 |
2023-06-07 |
Ligand Pharmaceuticals Inc. |
Kristalline formen und verfahren zur herstellung kristalliner formen einer verbindung
|
|
BR112021023782A2
(pt)
|
2019-05-27 |
2022-01-11 |
Immatics Us Inc |
Vetores, métodos de preparação de células t para imunoterapia, populações de células t expandidas e métodos para tratar de um paciente com câncer e para elicitar uma resposta imune
|
|
US12441730B2
(en)
|
2019-12-17 |
2025-10-14 |
Merck Sharp & Dohme Llc |
PRMT5 inhibitors
|
|
EP4076459A4
(de)
|
2019-12-17 |
2023-12-20 |
Merck Sharp & Dohme LLC |
Prmt5-inhibitoren
|
|
WO2021126732A1
(en)
|
2019-12-17 |
2021-06-24 |
Merck Sharp & Dohme Corp. |
Prmt5 inhibitors
|
|
CA3160153A1
(en)
|
2019-12-17 |
2021-06-24 |
Michelle Machacek |
Prmt5 inhibitors
|
|
US20230172996A1
(en)
|
2020-02-21 |
2023-06-08 |
Yoshikazu NAKAOKA |
Composition for alleviating pulmonary hypertension, method for predicting prognosis of pulmonary hypertension, method for assisting in determining severity of pulmonary hypertension, and method for assisting in diagnosing pulmonary hypertension
|
|
DE102020111571A1
(de)
|
2020-03-11 |
2021-09-16 |
Immatics US, Inc. |
Wpre-mutantenkonstrukte, zusammensetzungen und zugehörige verfahren
|
|
WO2022022865A1
(en)
|
2020-07-27 |
2022-02-03 |
Astrazeneca Ab |
Methods of treating chronic kidney disease with dapagliflozin
|
|
CA3116533A1
(en)
|
2020-07-27 |
2022-01-27 |
Astrazeneca Ab |
Methods of treating chronic kidney disease with dapagliflozin
|
|
CN116322682A
(zh)
|
2020-07-29 |
2023-06-23 |
艾米琳制药有限责任公司 |
在治疗儿科患者的高脂血症和高胆固醇血症的方法中使用的洛美他派
|
|
US20220056411A1
(en)
|
2020-08-21 |
2022-02-24 |
Immatics US, Inc. |
Methods for isolating cd8+ selected t cells
|
|
WO2023275715A1
(en)
|
2021-06-30 |
2023-01-05 |
Pfizer Inc. |
Metabolites of selective androgen receptor modulators
|
|
EP4469038A1
(de)
|
2022-01-26 |
2024-12-04 |
Astrazeneca AB |
Dapagliflozin zur verwendung bei der behandlung von prädiabetes oder zur verringerung des risikos der entwicklung von diabetes typ 2
|
|
CN120917311A
(zh)
|
2023-03-02 |
2025-11-07 |
卡西蒙生物技术有限责任公司 |
用于诊断癌症和/或急性炎性疾病的手段和方法
|
|
WO2025147589A1
(en)
|
2024-01-05 |
2025-07-10 |
Osanni Bio, Inc. |
Implants, compositions, and methods for treating retinal diseases and disorders
|
|
WO2025168652A1
(en)
|
2024-02-05 |
2025-08-14 |
Astrazeneca Ab |
Azd-0780 in combination with a statin for use in lowering ldl-c levels and treating cardiovacular diseases
|
|
TW202539678A
(zh)
|
2024-03-20 |
2025-10-16 |
瑞典商阿斯特捷利康公司 |
Pcsk9抑制劑及其使用方法
|
|
WO2025196155A1
(en)
|
2024-03-20 |
2025-09-25 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
WO2025196153A1
(en)
|
2024-03-20 |
2025-09-25 |
Astrazeneca Ab |
Pcsk9 inhibitors and methods of use thereof
|
|
WO2025238159A1
(en)
|
2024-05-16 |
2025-11-20 |
Astrazeneca Ab |
Combination therapy comprising azd0780 and ezetimibe
|