DK163667C - Fremgangsmaade til fremstilling af 7-amino-3-chlor-3-cephem-4-carboxylsyreestere - Google Patents

Fremgangsmaade til fremstilling af 7-amino-3-chlor-3-cephem-4-carboxylsyreestere

Info

Publication number
DK163667C
DK163667C DK179991A DK179991A DK163667C DK 163667 C DK163667 C DK 163667C DK 179991 A DK179991 A DK 179991A DK 179991 A DK179991 A DK 179991A DK 163667 C DK163667 C DK 163667C
Authority
DK
Denmark
Prior art keywords
cephem
chlor
amino
preparing
carboxylic acid
Prior art date
Application number
DK179991A
Other languages
English (en)
Other versions
DK179991A (da
DK179991D0 (da
DK163667B (da
Inventor
Lowell Deloss Hatfield
Larry Chris Blaszczak
Jack Wayne Fisher
Charles Arthur Bunnell
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27358615&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK163667(C) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/008,647 external-priority patent/US4226986A/en
Priority claimed from US06/008,470 external-priority patent/US4211702A/en
Priority claimed from US06/008,645 external-priority patent/US4223133A/en
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK179991A publication Critical patent/DK179991A/da
Publication of DK179991D0 publication Critical patent/DK179991D0/da
Publication of DK163667B publication Critical patent/DK163667B/da
Application granted granted Critical
Publication of DK163667C publication Critical patent/DK163667C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/04—Preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/04—Preparation from compounds already containing the ring or condensed ring systems, e.g. by dehydrogenation of the ring, by introduction, elimination or modification of substituents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D505/00—Heterocyclic compounds containing 5-oxa-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. oxacephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK179991A 1979-02-01 1991-10-30 Fremgangsmaade til fremstilling af 7-amino-3-chlor-3-cephem-4-carboxylsyreestere DK163667C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US06/008,647 US4226986A (en) 1979-02-01 1979-02-01 Process for halogenation of β-lactam compounds
US06/008,470 US4211702A (en) 1979-02-01 1979-02-01 Process for preparation of penicillin and cephalosporin imino halides
US864579 1979-02-01
US847079 1979-02-01
US06/008,645 US4223133A (en) 1979-02-01 1979-02-01 Cephalosporin reduction process
US864779 1979-02-01

Publications (4)

Publication Number Publication Date
DK179991A DK179991A (da) 1991-10-30
DK179991D0 DK179991D0 (da) 1991-10-30
DK163667B DK163667B (da) 1992-03-23
DK163667C true DK163667C (da) 1992-08-17

Family

ID=27358615

Family Applications (2)

Application Number Title Priority Date Filing Date
DK041480A DK163513C (da) 1979-02-01 1980-01-31 Fremgangsmaade til fremstilling af penicillin- eller cephalosporiniminohalogenider
DK179991A DK163667C (da) 1979-02-01 1991-10-30 Fremgangsmaade til fremstilling af 7-amino-3-chlor-3-cephem-4-carboxylsyreestere

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK041480A DK163513C (da) 1979-02-01 1980-01-31 Fremgangsmaade til fremstilling af penicillin- eller cephalosporiniminohalogenider

Country Status (32)

Country Link
EP (1) EP0014567B1 (da)
JP (12) JPS55113789A (da)
KR (1) KR830001901B1 (da)
AT (1) AT372684B (da)
AU (1) AU538175B2 (da)
BE (1) BE881425A (da)
BG (1) BG35899A3 (da)
CA (1) CA1133468A (da)
CH (3) CH652405A5 (da)
DD (1) DD153374A5 (da)
DE (1) DE3066119D1 (da)
DK (2) DK163513C (da)
ES (1) ES488231A0 (da)
FI (1) FI74968C (da)
FR (1) FR2447924A1 (da)
GB (1) GB2044256B (da)
GR (1) GR72278B (da)
IE (1) IE49377B1 (da)
IL (1) IL59269A (da)
IT (1) IT1193908B (da)
LU (1) LU82120A1 (da)
MA (1) MA18715A1 (da)
MW (1) MW880A1 (da)
MY (1) MY8500598A (da)
NL (1) NL191791C (da)
NO (1) NO160660C (da)
NZ (1) NZ192749A (da)
OA (1) OA06451A (da)
PH (1) PH15158A (da)
PL (4) PL129604B1 (da)
PT (1) PT70744A (da)
YU (4) YU22580A (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0348124B1 (en) * 1988-06-22 1994-04-27 Eli Lilly And Company Intermediate for 1-carba(dethia)cephalosporin
EP1961636B1 (en) 2007-02-20 2013-04-24 Yamaha Hatsudoki Kabushiki Kaisha Hydraulic master cylinder and vehicle provided with the same
JP5319035B1 (ja) 2012-03-09 2013-10-16 真一郎 谷 トレーニングラダー
US9741942B2 (en) 2012-10-11 2017-08-22 Merck Patent Gmbh Materials for organic electroluminescent devices
JP6202969B2 (ja) * 2013-10-01 2017-09-27 富士電機株式会社 情報処理装置、暗号化方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK118506B (da) * 1963-02-18 1970-08-31 Ciba Geigy Fremgangsmåde til fremstilling af 7-aminocephalosporansyre eller estere deraf.
US3641014A (en) * 1968-10-03 1972-02-08 Lilly Co Eli Reduction of delta**3-cephalosporin sulfoxides
US3925372A (en) * 1973-02-23 1975-12-09 Lilly Co Eli Alpha-aminoacyl-3-halo cephalosporins

Also Published As

Publication number Publication date
IT1193908B (it) 1988-08-31
DK41480A (da) 1980-08-02
JPH0372633B2 (da) 1991-11-19
IL59269A0 (en) 1980-05-30
DK179991A (da) 1991-10-30
IT8019609A0 (it) 1980-01-31
MY8500598A (en) 1985-12-31
JPH0372631B2 (da) 1991-11-19
GR72278B (da) 1983-10-11
EP0014567A1 (en) 1980-08-20
DE3066119D1 (en) 1984-02-23
FR2447924B1 (da) 1983-10-21
PL128595B1 (en) 1984-02-29
MA18715A1 (fr) 1980-10-01
PH15158A (en) 1982-08-24
YU22580A (en) 1983-06-30
JPH0649706B2 (ja) 1994-06-29
EP0014567B1 (en) 1984-01-18
JPH0371435B2 (da) 1991-11-13
JPH0649705B2 (ja) 1994-06-29
ES8101603A1 (es) 1980-12-16
IE800190L (en) 1980-08-01
JPH0372634B2 (da) 1991-11-19
PL126947B1 (en) 1983-09-30
JPH04356490A (ja) 1992-12-10
IE49377B1 (en) 1985-10-02
YU16483A (en) 1984-02-29
MW880A1 (en) 1981-09-09
BG35899A3 (en) 1984-07-16
AT372684B (de) 1983-11-10
LU82120A1 (fr) 1980-04-23
PL129604B1 (en) 1984-05-31
JPH0334982A (ja) 1991-02-14
JPH0565513B2 (da) 1993-09-17
FR2447924A1 (fr) 1980-08-29
CH652405A5 (fr) 1985-11-15
CH656385A5 (fr) 1986-06-30
NL191791C (nl) 1996-08-02
DK163513B (da) 1992-03-09
YU18283A (en) 1984-02-29
JPH07121950B2 (ja) 1995-12-25
YU16383A (en) 1984-02-29
JPS55113789A (en) 1980-09-02
JPH04364187A (ja) 1992-12-16
ATA50280A (de) 1983-03-15
DK179991D0 (da) 1991-10-30
AU538175B2 (en) 1984-08-02
NO160660C (no) 1989-05-16
PT70744A (en) 1980-02-01
JPH0517483A (ja) 1993-01-26
JPH089629B2 (ja) 1996-01-31
GB2044256B (en) 1983-05-05
YU44734B (en) 1991-02-28
BE881425A (fr) 1980-07-30
JPH0334981A (ja) 1991-02-14
DD153374A5 (de) 1982-01-06
ES488231A0 (es) 1980-12-16
JPH0565514B2 (da) 1993-09-17
JPH0334984A (ja) 1991-02-14
OA06451A (fr) 1981-07-31
JPH0372632B2 (da) 1991-11-19
NL8000545A (nl) 1980-08-05
IL59269A (en) 1984-04-30
JPH0532669A (ja) 1993-02-09
NO160660B (no) 1989-02-06
JPH0334985A (ja) 1991-02-14
GB2044256A (en) 1980-10-15
DK163667B (da) 1992-03-23
NO800251L (no) 1980-08-04
KR830001943A (ko) 1983-05-19
FI74968C (fi) 1988-04-11
JPH054991A (ja) 1993-01-14
FI800303A (fi) 1980-08-02
PL221744A1 (da) 1980-12-01
DK163513C (da) 1992-07-27
NZ192749A (en) 1983-06-17
JPH054990A (ja) 1993-01-14
CH648318A5 (fr) 1985-03-15
NL191791B (nl) 1996-04-01
FI74968B (fi) 1987-12-31
AU5502980A (en) 1980-08-07
JPH0334983A (ja) 1991-02-14
JPH0372231B2 (da) 1991-11-18
CA1133468A (en) 1982-10-12
PL129399B1 (en) 1984-05-31
KR830001901B1 (ko) 1983-09-19

Similar Documents

Publication Publication Date Title
DK147735C (da) Analogifremgangsmaade til fremstilling af 3-oxo-androst-4-en-17beta-thiocarboxylsyreestere
DK478980A (da) Fremgangsmaade til fremstilling af imidazol-5-eddikesyrederivater
DK42480A (da) Fremgangsmaade til fremstilling af 1-aryl-2-acylamido-3-fluor-1-propanoler
DK157760C (da) Fremgangsmaade til fremstilling af 7-(substitueret)-amino-3-substitueret-thiomethyl-cephemcarboxylsyrer
DK156828C (da) Fremgangsmaade til fremstilling af cyclopropancarboxylsyreesterderivater
DK157009C (da) Fremgangsmaade til fremstilling af 1-(3-mercapto-2s-methylpropionyl)-pyrrolidin-2s-carboxylsyre
DK396880A (da) Fremgangsmaade til fremstilling af cyclohexancarboxylsyrederivater
DK99980A (da) Fremgangsmaade til fremstilling af mercaptoacyldihydropyrazolcarboxylsyrederivater
DK540781A (da) Fremgangsmaade til fremstilling af 2-hydronaphthalen-6-carboxylsyre
DK157677C (da) Fremgangsmaade til fremstilling af cyclopropancarboxylsyreesterderivater
DK154554C (da) Fremgangsmaade til fremstilling af alfa-methyl-carbazol-2-eddikesyrederivater
DK163667C (da) Fremgangsmaade til fremstilling af 7-amino-3-chlor-3-cephem-4-carboxylsyreestere
DK158312C (da) Fremgangsmaade til fremstilling af diacetoneketogulonsyre
DK444279A (da) Fremgangsmaade til fremstilling af 6-hydroxymethyl-2-(beta-aminoethylthio)-1-carbadethiapen-2-em-3-carboxylsyre
DK535781A (da) Fremgangsmaade til fremstilling af n-pyrimidinyl-carbaminsyreestre
DK429779A (da) Fremgangsmaade til fremstilling af cyklopropancarboxylsyreestere
DK87382A (da) Fremgangsmaade til fremstilling af 1,4,5,6,7,8-hexahydro-2-alkyl-4-aryl-5-oxo-1,7-naphthyridin-3-carboxylsyreestere
DK145741C (da) Fremgangsmaade til fremstilling af 6-chlor-alfa-methyl-carbazol-2-eddikesyre
DK60081A (da) Fremgangsmaade til fremstilling af diphenylethercarboxylsyrer
DK354680A (da) Fremgangsmaade til fremstilling af substituerede (cyclo) alkancarboxylsyre-(alfa-cyano-3-phenoxy-benzyl)-estere
DK157613C (da) Fremgangsmaade til fremstilling af cyclopropancarboxylsyreesterderivater
DK57381A (da) Fremgansmaade til fremstilling af bifenyloxypropionsyrederivater
DK290680A (da) Fremgangsmaade til fremstilling af 2-formyl-3,3-dimethyl-cyclopropan-1-carboxylsyreestere
DK149962C (da) Fremgangsmaade til fremstilling af 2,5-diketogluconsyre
DK553781A (da) Fremgangsmaade til fremstilling af 2-beta-d-ribofuranosulthiazol-4-carboxid-estere

Legal Events

Date Code Title Description
A0 Application filed
PUP Patent expired