CY1118836T1 - Αντι-ιϊκα φωσφονικα αναλογα - Google Patents

Αντι-ιϊκα φωσφονικα αναλογα

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Publication number
CY1118836T1
CY1118836T1 CY20111100258T CY111100258T CY1118836T1 CY 1118836 T1 CY1118836 T1 CY 1118836T1 CY 20111100258 T CY20111100258 T CY 20111100258T CY 111100258 T CY111100258 T CY 111100258T CY 1118836 T1 CY1118836 T1 CY 1118836T1
Authority
CY
Cyprus
Prior art keywords
viscal
phosphone
analogues
compounds
administration
Prior art date
Application number
CY20111100258T
Other languages
English (en)
Inventor
Constantine G Boojamra
Carina E Cannizzaro
James M Chen
Xiaowu Chen
Aesop Cho
Lee S Chong
Maria Fardis
Haolun Jin
Ralph F Hirschmann
Alan X Huang
Choung U Kim
Thorsten A Kirschberg
Christopher P Lee
William A Lee
Richard L Mackman
David Y Markevitch
Vidya K Prasad
Hyung-Jung Pyun
Adrian S Ray
Rosemarie Sherlock
Sundaramoorthi Swaminathan
Will Watkins
Jennifer R Zhang
David Oare
Original Assignee
Gilead Sciences, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences, Inc. filed Critical Gilead Sciences, Inc.
Publication of CY1118836T1 publication Critical patent/CY1118836T1/el

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    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
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    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

Η εφεύρεση αναφέρεται σε ενώσεις υποκατεστημένες με φώσφορο με αντί-ιϊκή δραστικότητα, συνθέσεις που περιέχουν αυτές τις ενώσεις, και θεραπευτικές μεθόδους που περιλαμβάνουν τη χορήγηση αυτών των ενώσεων, καθώς επίσης σε διεργασίες και ενδιάμεσα χρήσιμα για την παρασκευή αυτών των ενώσεων.
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